* Alchemist's Acid Spray can heavily damage Chen's creeps and disrupt his jungling.
* Alchemist builds items like Radiance and Battle Fury, allowing him to quickly clear Chen's creeps.
* Alchemist's Greevil's Greed will grant him more bonus gold as he kills Chen's creeps.

* Aphotic Shield can nullify Chen's combo, while clearing Chen's creeps simultaneously.

* Chemical Rage kills Phoenix very quickly in Supernova.

* Heroes that deal damage over time will also fail to bring down Abaddon and his allies, such as Huskar, Venomancer, or Phoenix.

* Magnus has very mediocre damage against Alchemist, because he can survive the stun duration of Reverse Polarity with Chemical Rage.

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

* Chemical Rage mitigates damage from Burning Spear.
Additional:
* Chemical Rage negates almost all damage from Burning Spears.

* Heroes that deal damage over time will also fail to bring down Abaddon and his allies, such as Huskar, Venomancer, or Phoenix.

Additional:
* Huskar's damage over time gives Abaddon the opportunity to shield and heal his allies.
* Borrowed Time also makes Abaddon a hard support to gank, thus negating Huskar's early game dominance.

* Borrowed Time mitigates the damage by Pierce the Veil for most of its duration.
* Muerta has no control over Gunslinger, making her one of the best heroes for Abaddon to regenerate from via Borrowed Time

* Abaddon could punish Chaos Knight for using his Phantasm and Reality Rift combo on him with Aphotic Shield. Additionally, it provides extra protection against Chaos Knight's potential to take Abaddon down quickly.
* Furthermore, Abaddon's Borrowed Time makes it utterly impossible to burst Abaddon down, effectively reducing the amount of targets Chaos Knight can threaten by 1 for the entire game.

* Sticky Napalm, Flaming Lasso, and Flamebreak can all be instantly dispelled by Aphotic Shield.
* Firefly will continuously heal Abaddon under Borrowed Time.
Additional:
* Aphotic Shield and Borrowed Time can both dispel Flaming Lasso.

* Nightmare and Fiend's Grip can be instantly dispelled by Aphotic Shield.
* Bane lacks mobility, therefore becoming helpless when silenced by Curse of Avernus.
Additional:
* Aphotic Shield applies a strong dispel on the allied target and can be used to remove both Fiend's Grip & Nightmare.
* Borrowed Time applies a strong dispel on Abaddon and can instantly remove both Fiend's Grip & Nightmare when activated.
* Bane, when caught by Curse of Avernus struggles to escape because of his innately low mobility.

* Aphotic Shield dispels Thunder Strike.
* Mist Coil can be used to heal an ally trapped by Static Storm-Kinetic Field combo.
* Borrowed Time makes Abaddon nearly impossible to gank.

* Aphotic Shield prevents damage and dispels the slow from Snapfire's Mortimer Kisses.
* Borrowed Time allows Abaddon to gain HP during Snapfire's Mortimer Kisses.

* Aphotic Shield makes it less likely for allies to be killed by mines.
* Because they explode in very short intervals, a stack of Remote Mines will always trigger Borrowed Time, making them impossible to kill Abaddon unless his resistances are lowered enough or Abaddon is affected by Break.
* Abaddon can easily dispel the long-lasting root of Stasis Trap on himself and on an ally, while at the same also providing protection against the other mines' damage.
Additional:
* Borrowed Time's automatic activation will help Abaddon survive a field of Proximity Mines or a Blast Off combo. However, the damage from a single mine can kill him if his HP is low enough.
* Aphotic Shield's can easily break Techies' Etheral Blade combo.

* If Rupture is used on Abaddon, Abaddon can use Borrowed Time and easily heal for the duration of Borrowed Time by simply moving.
Additional:
* Borrowed Time makes Abaddon nearly impossible to gank.
* Aphotic Shield and Mist Coil prevents Bloodseeker from gaining his Thirst bonuses.

* Aphotic Shield is a strong dispel, meaning it can save allies from Earth Spirit's stun, slow, silence, and Magnetize.
* Borrowed Time makes it nearly impossible for Earth Spirit to kill Abaddon.

* Borrowed Time can give Abaddon a second chance after a Black Hole combo.
* Aphotic Shield can be used to save allies or Abaddon himself from Malefice.
* Abaddon can easily heal himself as well as his allies during a team fight, especially with Aghanim's Scepter upgraded Borrowed Time.

* Primal Roar can be instantly dispelled by Aphotic Shield.
* The debuffs from Wild Axes and Poison from Call of the Wild: Boar can also be dispelled by Aphotic Shield.
Additional:
* Aphotic Shield effectively nullifies Primal Roar's single-target initiation on allies.
* Even being initiated by Primal Roar, Borrowed Time can make Abaddon extremely difficult to kill.

* If he isn't broken (break), Abaddon can use Borrowed Time to waste Legion Commander's Duel, As Borrowed Time has a shorter cooldown, Legion Commander can't win duels, effectively reducing her targets by one, Duel also means that Borrowed Time heals Abaddon for the duration of the duel, as Legion can't stop attacking.
Additional:
* Aphotic Shield and Mist Coil makes it hard for Legion Commander to kill Abaddon's teammates in Duels.
* Borrowed Time makes Abaddon nearly impossible to kill in Duels, and often replenishes much of his health because Legion Commander cannot manually stop attacking during Duels.

* Chemical Rage will take down Tombstone in no time.
Additional:
* With Greevil's Greed, Alchemist can farm Tombstone zombies and gain a significant gold advantage.

* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with Aphotic Shield, or remove it from himself with Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.

* Alchemist can easily farm Spiderlings with Acid Spray and Greevil's Greed.
* Alchemist's Chemical Rage nullifies Broodmother's Insatiable Hunger
Additional:
* Greevil's Greed makes Broodmother’s spiderlings far more valuable to Alchemist making it important that he does farm them as opposed to other heroes where the spider's bounties are negligible.
* Acid Spray makes it difficult to attack Alchemist in lane without losing some spiderlings to the damage over time, potentially giving him farm he wouldn't have otherwise.

* Exorcism will continuously heal Abaddon under Borrowed Time, and cannot be turned off.
* {Ability ID:Spirit Siphon|Death Prophet} will continuously heal Abaddon under Borrowed Time, for a percentage of his maximum health.

* Both Lion's Finger of Death and Lina's Laguna Blade have a 0.25 second delay before the damage is dealt.

Additional:
* Although Finger of Death can potentially bypass Borrowed Time, Finger's delayed damage allows an Abaddon with fast enough reaction time to activate Borrowed Time and heal from Finger.
* Aphotic Shield is extremely effective against both Earth Spike and Hex, nullifying the stun or hex while preventing further damage.
* Lion's lack of escape mechanisms allows Abaddon and his allies to pursue him with Curse of Avernus.

* The health regeneration and bonus movespeed from Chemical Rage allows Alchemist to survive through Doom very easily.
* Doom's low armor makes him weak against Alchemist's high physical damage output.
Additional:
* Chemical Rage out-heals Doom to a large degree throughout all stages of the game. Should Alchemist be chemically enraged before being Doomed, Alchemist can become a difficult target to effectively lockdown and kill, thanks to the health regeneration and movement speed bonuses granted by his ultimate.
* Alchemist is an ineffective target for Doom. Alchemist isn't totally reliant on his skills to be effective during a teamfight, due to the right-click nature of the hero.

* Heroes with the ability to heal allies, or those with good defensive abilities: Chen, Dazzle, Io, Oracle, Omniknight, Witch Doctor, Winter Wyvern, Abaddon, etc.

* Abaddon's constant heals and protection can save himself and his allies from burst-focused heroes, such as Legion Commander, Faceless Void, and Pudge.

Additional:
* Mist Coil and Aphotic Shield enable Abaddon to keep an ally alive during Chronosphere.
* Borrowed Time prevents Faceless Void from killing Abaddon during his Chronosphere.

* Heroes that can purge his slow and disables are very difficult to go on and their team: Abaddon, Oracle.

* He can quickly take out heroes with low armor (Tiny) with his great physical damage.

* In general, heroes that deal burst in multiple instances will trigger Borrowed Time and heal Abaddon for a large amount, such as Skywrath Mage, Techies, Juggernaut, Shadow Shaman, or Ogre Magi.

* By simply using Aphotic Shield, Abaddon can easily save his allies from heroes that apply long disables, such as Lion or Shadow Shaman.

* Abaddon's constant heals and protection can save himself and his allies from burst-focused heroes, such as Legion Commander, Faceless Void, and Pudge.

Additional:
* Abaddon can activate Borrowed Time to dispel Dismember; breaking the disable and potentially allowing Abaddon to escape.
* Aphotic Shield can be cast on an ally to dispel the stun of Dismember, which can make kills difficult to secure, given that Dismember is Pudge's only reliable disable.
* Pudge lacks a mobility without a Blink Dagger, causing him to be easily chased with Curse of Avernus. The silence also prevents him from toggling off his Rot.

* Clockwerk lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Clockwerk finishes his initiation. Additionally, Clockwerk hates buying Dagon and Ethereal Blade, which are the only itmes that can help him deal with heroes who can recover themselves and turn the fight around to their advantage: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* In general, heroes that deal burst in multiple instances will trigger Borrowed Time and heal Abaddon for a large amount, such as Skywrath Mage, Techies, Juggernaut, Shadow Shaman, or Ogre Magi.

* Heroes that require burst damage to kill will be difficult for Phantom Lancer to take down: Timbersaw, Axe, Bristleback, Alchemist and Underlord

* Heroes that deal damage over time will also fail to bring down Abaddon and his allies, such as Huskar, Venomancer, or Phoenix.

Additional:
* Borrowed Time & Aphotic Shield can dispel Venomous Gale and Poison Sting.

* Abaddon with Aphotic Shield and Borrowed Time
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Acid Spray and Greevil's Greed will quickly destroy pushes with treants.
* Because of his poor movement speed,Alchemist can catch up and kill him with Chemical Rage.

* Impale and Spiked Carapace stun can be instantly dispelled by Aphotic Shield.
* Abaddon can use Borrowed Time and easily heal for the duration of Borrowed Time by Nyx's burst damage.

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* If he isn't silenced, Abaddon can use Borrowed Time to escape Reaper's Scythe during the delay.

* Abaddon can cast Aphotic Shield on any of his allies to immediately dispel Corrosive Haze and/or the stun and the slow components of Slithereen Crush.
* All of Slardar's debuffs are also removed if Abaddon's Borrowed Time triggers.