* Enchantress's lack of AoE abilities allows Broodmother to swarm her with Spiderlings.
* Spawn Spiderlings can kill enchanted creeps.
* However, keep in mind that Untouchable makes it harder for Brood to actually hit Enchantress, even if Broodmother is spell immune.
Additional:
* Enchantress can be easily overwhelmed with Broodmother's spiderlings from Spawn Spiderlings and Enchantress can only control one of them with Enchant and she has no good waveclear (Spawn Spiderlings can also kill creeps controlled with Enchant).
* However, Untouchable's attack speed reduction can make it difficult for Broodmother to kill Enchantress even with any form of spell immunity.

* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.

* Broodmother can kill Enigma's Eidolons with Spawn Spiderlings, and spawn her spiderlings in their place. But remember that Enigma can do the same to Broodmother's spiderlings with Demonic Conversion and Midnight Pulse.
* Without the protection from Black King Bar, Broodmother can cancel Enigma's Black Hole with Bloodthorn and make him more vulnerable to damage. Broodmother can also buy Abyssal Blade to cancel Enigma's Black Hole even through Black King Bar.
* Silken Bola causes Enigma's attacks to miss a lot and renders him more vulnerable to magical damage. And if Broodmother takes 400 AoE Silken Bola, then she will be able to use to cause Enigma's Eidolons to miss their attacks as well. In addition, Enigma does not like to buy items to provide him true strike such as Bloodthorn, Monkey King Bar, Witch Blade and it's upgrade Revenant's Brooch.
* If Broodmother is lucky enough to survive being trapped in Black Hole, she will be able to recover her lost health with Insatiable Hunger.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Enigma, deal damage over time to Enigma and reveal Enigma if he unwittingly steps on them, disrupting his attempts to initiate with Black Hole, prevent him from using Blink Dagger, while also alerting Broodmother on his attempts to ambush her and her allies.
Additional:
* Broodmother can kill Enigma's Eidolons with Spawn Spiderlings, and spawn her spiderlings in their place. But remember that Enigma can do the same to Broodmother's spiderlings with Demonic Conversion and Midnight Pulse.
* Without the protection from Black King Bar, Broodmother can cancel Enigma's Black Hole with Bloodthorn and make him more vulnerable to damage. Broodmother can also buy Abyssal Blade to cancel Enigma's Black Hole even through Black King Bar.
* Silken Bola causes Enigma's attacks to miss a lot and renders him more vulnerable to magical damage. And if Broodmother takes 400 AoE Silken Bola, then she will be able to use to cause Enigma's Eidolons to miss their attacks as well. In addition, Enigma does not like to buy items to provide him true strike such as Bloodthorn, Monkey King Bar, Witch Blade and it's upgrade Revenant's Brooch.
* If Broodmother is lucky enough to survive being trapped in Black Hole, she will be able to recover her lost health with Insatiable Hunger.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Enigma, deal damage over time to Enigma and reveal Enigma if he unwittingly steps on them, disrupting his attempts to initiate with Black Hole, prevent him from using Blink Dagger, while also alerting Broodmother on his attempts to ambush her and her allies.

* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult.
* Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.

* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.
Additional:
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa.

* Heroes with summons: Lycan, Broodmother, Visage, Nature's Prophet, Warlock.

* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces Rage, wasting its cooldown and making Lifestealer unable to fight.

* Chen's low mobility and lack of AoE abilities makes him an easy target for Broodmother and her Spiderlings.
* Broodmother can easily pick off Chen's creeps with Spawn Spiderlings, and by ambushing them through terrain in her web.
Additional:
* Chen has no area-of-effect spells to deal with Broodmother's spiderlings and must rely on his creeps to take care of them.
* Spawn Spiderlings can kill Chen's creeps and spawn spiderlings in their place.
* Spin Web allows Broodmother to disrupt Chen's jungling.

* Heroes with strong area-of-effect damage can make quick work of Chen's converted creeps and at same time gain farm: Magnus, Jakiro, Shadow Fiend, Kunkka, Luna, Dragon Knight, Medusa, Alchemist.

* Heroes with very little to no area-of-effect abilities will struggle greatly against Broodmother: Sniper, Phantom Assassin, Nyx Assassin, Bane, Visage, Bounty Hunter.

* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.

* Sprout cannot protect Nature's Prophet if Broodmother puts down a web.
* Nature's Prophet's low mobility means he is defenseless against Incapacitating Bite.
* Spiderlings can absorb much of the damage from Wrath of Nature.
Additional:
* Broodmother can destroy Nature's Prophet's Treants with Spawn Spiderlings and summon spiderlings in their place.
* Broodmother loves buying Orchid Malevolence, which can prevent Nature's Prophet from escaping with Sprout and Teleportation.

* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.

* Broodmother can easily clear Wraith King's skeletons with Spawn Spiderlings and summon spiderlings in their place.
* With Diffusal Blade, Broodmother can prevent Wraith King from reincarnating unless Wraith King has his Aghanim's Shard.

* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.

* Viper's lack of escape and durability means he can be ran over in a laning stage by Spawn Spiderlings.
* Broodmother can bring Viper down quickly with Insatiable Hunger activated.

* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.

* Bounty Hunter's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to stop Bounty Hunter from escaping with Shadow Walk.
Additional:
* Like with Bane, Bounty Hunter's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to stop Bounty Hunter from escaping with Shadow Walk.

* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.

* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.

* Spiderlings melt away Living Armor almost instantly.
* The vision from Eyes In The Forest may prove dangerous for Broodmother, however.

* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

* Heroes with blind of some sort can be a bad choice for Monkey King to go on: Broodmother, Riki, Keeper of the Light.

* Illusion-based and multi-unit heroes can take advantage of Chaos Knight's lack of area damage: Naga Siren, Phantom Lancer, Broodmother

* Heroes with plenty of summons, such as Broodmother or Nature's Prophet can have their minions soak up most of your Paralyzing Cask.

* Heroes with summons like Broodmother, Enigma, Nature's Prophet; or illusions, like Naga Siren, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity Mines.

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.

* Clockwerk lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Clockwerk finishes his initiation. Additionally, Clockwerk hates buying Dagon and Ethereal Blade, which are the only itmes that can help him deal with heroes who can recover themselves and turn the fight around to their advantage: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

Additional:
* Chain Frost can bounce to the Spiderlings that Broodmother spawns.

* Heroes with Linken's Sphere as core item: Weaver, Morphling, Medusa.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirit's weak area-of-effect: Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock.

* Oracle cannot easily deal with swarms of units, making him weak against heroes like Phantom Lancer or Broodmother.

* Heroes with illusions and summons can manfight Night Stalker: Terrorblade, Beastmaster, Broodmother.

* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.

* If Medusa activates Stone Gaze, the charge will inevitably fail.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation.

* Drow Ranger's lack of mobility makes her easy prey for Broodmother and her Spiderlings.

* Medusa's Split Shot will whittle down all of Naga Siren's illusions, including Naga Siren herself.

* Sniper is completely helpless against Broodmother's abilities, and can be seriously damaged by Spiderlings in lane, especially when Shrapnel is on cooldown.

* Heroes who can summon illusions and summons because Terrorblade has no abilities to deal with multiple enemies at once outside Reflection: Shadow Shaman, Naga Siren, Broodmother, Lycan, Enigma, Chaos Knight, Phantom Lancer, Shadow Demon, Dark Seer, Nature's Prophet, Invoker, Morphling, Visage, Grimstroke with Aghanim's Scepter.

* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.

* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to manfight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalise on his commitment in a fight.

* Broodmother can kill Invoker easily in the early game with her Spawn Spiderlings and her spiderlings.
* Broodmother is both an Orchid Malevolence and a Nullifier carrier. As she can farm it early, she can kill Invoker easily.

* Bane's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to cancel Fiend's Grip, and completely shut Bane down.
Additional:
* Bane's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to cancel Fiend's Grip, and completely shut Bane down.

* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.

* Mana Shield tanks most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.

* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.

* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.

* Broodmother relies less on abilities and more on right-clicks.
* Spiderlings can overwhelm Silencer, who has mediocre armor and no escape tool.

* None of Arc Warden's abilities are very effective against Broodmother and her spiderlings.
* A good Broodmother looks to end the match early while Arc Warden, a very item reliant hero, thrives in longer matches.
* Arc Warden has no innate disables to stop Broodmother from lifestealing with Insatiable Hunger and shredding through his relatively lower armor.

* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.