* Sniper is very fragile, along with his low movement speed, make an exceptionally easy target for Chaos Knight to initiate on.
* Sniper has no innate ability to deal with Phantasm or escape a Reality Rift and Chaos Bolt combo.
* In most cases, Sniper likes to stay far in the backline to deal damage, thus he is vulnerable if Chaos Knight manages to jump in the back line, which will usually spell a quick end for Sniper.

* Assassinate is easy to reflect with Spiked Carapace for massive damage.
* Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.

* Life Drain does not instantly kill the illusions from Phantasm
* Chaos Bolt and Reality Rift can easily interrupt the channeling from Life Drain.
* Reality Rift makes it harder for Pugna to keep his distance between Chaos Knight.
* Nether Ward barely deals any significant damage on Chaos Knight as Chaos Knight's abilities do not cost a lot of mana
* The overwhelming damage of Chaos Knight and his illusions will do a quick work on Pugna's poor HP pool, or safely remove the Nether Ward from the battlefield.

* Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel Life Drain, making him easy to hit with Impale.
Additional:
* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mana Burn will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.

* Phantasm's illusions make it difficult to land Meat Hook and Dismember.
* Chaos Bolt is a comparatively low cooldown tool to interrupt Dismember.
* Chaos Strike's lifesteal offsets Rot's damage.
Additional:
* Unlike any other illusion heroes, Chaos Knight is the worst target for Pudge to hook as it will definitely backfire him.
* Phantasm are significantly tankier than most illusion and deal full damage, which will quickly kill Pudge due to his low armor.
* it becomes worse if pudge is affected with Reality Rift, which reduces his already abysmal base armor even lower.
* Low movement speed and low mobility means Pudge will struggle to escape or outrun Chaos Knight in most cases.

* Mana Burn drains Pudge's little mana which may render Meat Hook and Dismember unusable.
* Impale and Spiked Carapace can be used to cancel Dismember easily, and can even do so when Pudge uses it on Nyx Assassin, if timed correctly.

* Unlike with other heroes who can summon illusions of themselves, Terrorblade's illusions from Conjure Image have different colors than other illusions which can be seen even by enemy team, which can also make Terrorblade weak even against heroes he naturally counters: Bane, Lifestealer, Spectre, Chaos Knight, Spirit Breaker, Sniper. Terrorblade's only solution to counter this problem is to get Manta Style as quickly as possible.

* Nyx Assassin deals large amounts of pure damage with Vendetta and magical damage with Impale and Mana Burn, allowing him to ignore Terrorblade's armor and burst his low health pool down before he can use Sunder.
* Nyx Assassin commonly buys Urn of Shadows, Dagon and Meteor Hammer which deal magic damage that ignore Terrorblade's armor.
* Mana Burn might drain too much mana for Terrorblade to be able to use Sunder if he isn't careful in the early to mid game.

* Phantasm removes Glimpse and dispels Thunder Strike. Additionally, the Phantasm illusions make it difficult to use Glimpse and Thunder Strike on the real Chaos Knight.
* Disruptor's lack of mobility, combined with his lack of innate defense, sets him up for a Reality Rift and a beatdown by Chaos Knight and his illusions.

* Heroes that can pick you off: Clinkz, Nyx Assassin, Puck, Riki.

* Heroes who relies on illusions and summons (Beastmaster, Chaos Knight, etc.).

* Vendetta disables Vengeance Aura and allows him to attack Vengeful Spirit with Impale and Mana Burn.
* Spiked Carapace is easy to use against a Wave of Terror or Magic Missile.

* Warlock is a very strong hero when positioned correctly, and his long cast range helps him with this. However, some Heroes might disrupt or sneakily pass through his allies and deal with him, preventing him from doing his job. Such heroes include Chaos Knight, Spirit Breaker, Riki, and more.

* Impale and Spiked Carapace interrupts Upheaval with ease.
* Warlock's low health pool, mobility, and high intelligence gain makes him a prime target for Nyx Assassin's burst damage.

* Innately fragile heroes will die almost instantly to Reality Rift while Chaos Knight has illusions active: Drow Ranger, Bane, Necrophos, Crystal Maiden.

Additional:
* Reality Rift will disable Drow Ranger's Marksmanship, along with Chaos Bolt he can keep her locked for enough time to be killed.

* Nyx Assassin has a lot of burst damage from his Impale, Mana Burn, Dagon, and the bonus damage from Vendetta. All of this damage is enough to kill Drow Ranger.
* Nyx Assassin is usually invisible most of the time thanks to his ability Vendetta, which allows him to gank Drow Ranger easily.

* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Naga Siren, Terrorblade.

* Heroes with heavy early and mid-game magical damage are also problematic for Phantom Assassin due to being able to easily kill her before she gains an item advantage: Lina, Necrophos, Nyx Assassin, Gyrocopter. Should be noted these heroes are usually quite squishy and don't scale well with health. So to some respect, they are on a time crunch.

* Single-target disablers will have difficulty locking down a Chaos Knight with Phantasm active: Bane, Beastmaster, Bloodseeker, Clockwerk, Doom, Shadow Shaman.

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill Shadow Shaman, Nyx being particularly deadly. Shadow Shaman must watch out for Slark carefully, as he can break either (but not both unless he makes a mistake) of Shadow Shaman's disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn Shadow Shaman from prey to predator.

* Skywrath Mage also has a terrible time fighting against anything that isn't a hero. His skills are mostly target-based and he has terrible strength and agility, he can easily be kited or harassed by illusion-based heroes like Chaos Knight and Phantom Lancer, or by Heroes that summon other units like Lone Druid, Lycan and Beastmaster.

* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos

Additional:
* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* Mana Burn is annoying at all stages of the game as it turns Skywrath Mage's high intelligence growth against him.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirit's weak area-of-effect: Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Illusion and heroes with summons are difficult to kill with Chen's single-target offensive spells: Terrorblade, Phantom Lancer, Chaos Knight, Broodmother, Naga Siren, Lycan, Visage. And even though Chen can convert enemy summons with Holy Persuasion, their much greater numbers will often overwhelm Chen and his creeps.

* Heroes with damage burst can often kill Chen or his allies before he can use Hand of God: Lina, Luna, Techies, Shadow Fiend, Pugna, Nyx Assassin.

* As a counter to most casters,Nyx will shut down Muerta with only a few items.
* Nyx's Mana Burn can make short work of Muerta's high intelligence pool.
* Spiked Carapace and Vendetta can help Nyx escape or imitate when needed.

* Level 4 Mana Burn burns of Medusa's mana every 5 seconds if Medusa only increases her mana pool with intelligence. Additionally, 70% of the Mana Burn damage gets mitigated by Mana Shield, burning even more mana.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.

* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.

* Nyx's Spiked Carapace can reflect the damage of Sharpshooter, instantly killing hoodwink. Nyx can also use Vendetta to position himself in such a way to screen allies from Sharpshooter and catch Hoodwink by surprise.

* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity, even if Batrider is focusing on other enemy hero.

* Chaos Bolt and Reality Rift makes Tiny's low mobility non existent.
* Chaos Strike means Chaos Knight will most likely survive longer in a duel between the two because Tiny has much lower attack speed.
* Chaos Knight has a 3.2 strength growth, making him one of the most tanky heroes and a very difficult target for Tiny to burst.

* Nyx Assassin takes advantage of Invoker's massive intelligence gain and mana pool to do tons of damage using Mana Burn, as the spell does more damage based on the target's intelligence.
* Nyx Assassin can simply activate Spiked Carapace while under many Invoker's abilities to stun him.

* Phantasm dispels Ignite and makes targeting the real Chaos Knight much harder.

* Spiked Carapace can be used to reflect Illuminate damage and stun Keeper of the Light.
* Vendetta allows Nyx Assassin to follow Keeper of the Light around if he tries to split-push.
* Keeper of the Light is very squishy and will very quickly die to Vendetta and it's followup abilities.
* However, Mana Burn's Mana Burn can be more or less mitigated with Chakra Magic.

* Mana Burn removes much-needed mana for Ball Lightning.
* Spiked Carapace triggers on Static Remnant for an easy stun.
Additional:
* Mana Burn is capable of removing most of Storm Spirit's large mana pool, along with dealing heavy damage and quickly depleting his chances of escaping a gank or fight.

* Innately fragile heroes will die almost instantly to Reality Rift while Chaos Knight has illusions active: Drow Ranger, Bane, Necrophos, Crystal Maiden.

* Crystal Maiden has a very bad movement speed, so Impale is easy to land against her. Furthermore, even while trapped by Frostbite, Nyx Assassin can still cast Impale.
* Crystal Maiden has very low armor, so Vendetta is very effective.
* Nyx Assassin has two ways to stop Freezing Field, provided she doesn't get a Black King Bar. He can either pop Spiked Carapace and simply walk into the field, or he can use Impale to interrupt the field, since Crystal Maiden has to channel it.
Additional:
* Spiked Carapace easily interrupts Freezing Field.
* Frostbite's damage over time sets up an easy Spiked Carapace stun.
* Crystal Maiden is extremely fragile and dies quickly to Nyx Assassin's burst damage.

* Chaos Knight's high health pool makes him resistant to Zeus' burst damage. Phantasm can dispel Veil of Discord, a typical item purchased by Zeus.
* Zeus is easily overwhelmed by Chaos Knight's strong illusions, as Arc Lightning is not enough to kill them fast enough to have any impact.
* Zeus' low base armor makes him extremely vulnerable to Chaos Knight's high damage output and armor reduction.

* Nyx Assassin's Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* Mana Burn deals high damage due to Leshrac's high intelligence gain and burns a large amount of Leshrac's essential mana pool.

* Mana Burn does tons of damage against Lina because of her high intelligence. The mana burn also prevents Lina from casting her full combo.
* Spiked Carapace can easily be used to counter Lina's abilities because of their long cast animation, and could probably kill Lina outright if Laguna Blade is reflected.

* Innately fragile heroes will die almost instantly to Reality Rift while Chaos Knight has illusions active: Drow Ranger, Bane, Necrophos, Crystal Maiden.

* The huge physical damage taken from Vendetta will force Necrophos to use Ghost Shroud, which is good for a followup with Dagon and Ethereal Blade, both of which are common items on Nyx Assassin.
* Using Ghost Shroud also sets Necrophos up for a Mana Burn or Impale.

* Spiked Carapace allows Nyx to get an easy long-duration stun on Weaver once he uses Shukuchi, and then he can follow up with Impale.
* Vendetta works as a great setup for both Impale and Spiked Carapace and can deal decent damage to Weaver. Additionally he can neutralize The Swarm beetles due to his invisibility duration.

* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.

* Dark Pact is minimally effective against Phantasm illusions, and Slark lacks area damage otherwise.
* Pounce can be counteracted by Reality Rift.
* Slark is naturally frail and dies quickly to Chaos Knight's burst damage before he can build Essence Shift stacks.
* Be aware, however, that Shadow Dance can make Slark hard to kill as he can't be targeted during its duration.
Additional:
* Phantasms have enough health to survive Dark Pact, and Slark has no other source of AoE damage to deal with them.

* Razor has no way to deal with Chaos Knight's multiple illusions from Phantasm.

* Ursa cannot effectively fight against Phantasm's illusions with his single-target damage.
* Chaos Bolt's potentially long stun with Chaos Bolt gives Ursa little opportunity to Enrage.
Additional:
* Ursa has no way to clear illusion quickly, making him vulnerable to Chaos bolt and Phantasm combo.
* Reality Rift can quickly relocate or reinitiate on Ursa once the duration of Enrage is over.
* Phantasm can be used to dispel Earthshock's slow. Manta Style is another item that counter Ursa greatly.
* Ursa has low mobility, once jumped on by Reality Rift, Ursa struggles to escape.

* Last Word is extremely easy to reflect with Spiked Carapace for large amounts damage, due to triggering when Nyx Assassin casts a spell, but can still silence Nyx Assassin. It also has the added bonus of dealing more damage the more Intelligence Silencer has.
* Glaives of Wisdom quickly builds Silencer's Intelligence, making him a particularly prime target for Mana Burn.
* Silencer rarely builds survivability items, nor is he able to steal much Intelligence while surrounded by his team, and so is an excellent target for Vendetta.
* Silencer has no reliable way of dealing with a burrowed Nyx, and also lacks the ability to prevent Nyx from escaping with Vendetta,
Additional:
* Silencer is rather squishy and has poor mobility without items, making him an easy target for Nyx.
* Silencer's intelligence steal ability is a complete disadvantage against Nyx Assassin as Mana Burn will deal increasing damage for each point of intelligence Silencer has stolen, turning Silencer's intelligence steal against him.

* Huskar's low armor and movement speed make an easy target for Chaos Knight to initiate on with Reality Rift and Chaos Bolt.
* Beside Inner Fire, Huskar has no reliable area of effect ability to clear Phantasm illusions.
* Huskar likes to fight at low health to benefit from his Berserker's Blood, thus vulnerable to Chaos Knight's high burst physical damage.
Additional:
* Chaos Bolt can stun Huskar when he jump in with Life break, giving 4 seconds maximum for Chaos Knight to deliver a beatdown.
* Reality Rift further reduces Huskar's low armor, boosting Chaos Knight's damage even more.
* Berserker's Blood offer no protection against Chaos Strike, which deal physical damage.
* Phantasm can be used to dispel the disarm from Inner Fire.
* Although Huskar can use this to disarm the illusion instead, buying himself some times.

* Nyx Assassin can reflect Life Break with Spiked Carapace.

* Chaos Knight can dispel Flux with Phantasm.
* Chaos Knight can use Reality Rift to pull Arc Warden out of Magnetic Field.
* Once Chaos Knight jumps on Arc Warden with Reality Rift, Arc Warden will struggle to escape due to low mobility and lack of stun.

* Reality Rift lets Chaos Knight bypass the Spirit Bear and jump onto Lone Druid.
* The Spirit Bear's lack of scaling means it dies quickly to Chaos Knight during the late-game.

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin.

* Chaos Knight, Lone Druid, Meepo and Arc Warden can be hard targets since Shadow Demon's spells are ill-suited to fight many enemies at once.

* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna

* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light, Dawnbreaker.

* Heroes with illusions and summons can swarm Bane, who has no area abilities outside from Aghanim's Shard upgraded Brain Sap: Broodmother, Chaos Knight, Naga Siren, Nature's Prophet, Phantom Lancer, Terrorblade, Visage, Warlock, Wraith King.

Additional:
* Phantasm's illusions make it difficult for Bane to target Chaos Knight with Nightmare, Enfeeble, and Fiend's Grip.
* Chaos Bolt is a comparatively low cooldown tool to interrupt Fiend's Grip.
* Nightmare can be transferred by Phantasm illusions.

* Phantasm gives Chaos Knight a significant advantage against single-target damage dealers: Lifestealer, Wraith King, Night Stalker, Troll Warlord.

Additional:
* Wraith King has no form of AoE to clear Chaos Knight's illusions from Phantasm.
* Wraith King is very vulnerable if he reincarnates in the middle of his illusions.

* Single-target disablers will have difficulty locking down a Chaos Knight with Phantasm active: Bane, Beastmaster, Bloodseeker, Clockwerk, Doom, Shadow Shaman.

* Phantasm gives Chaos Knight a significant advantage against single-target damage dealers: Lifestealer, Wraith King, Night Stalker, Troll Warlord.

Additional:
* Chaos Knight's tanky illusions easily take advantage of Troll Warlord's lack of AoE damage.
* Chaos Bolt can stun Troll for up to 4 seconds and Reality Rift prevents Troll Warlord from chasing down foes.
* Phantasm increases Chaos Knight's physical damage output up to 4 times and can easily kill Troll Warlord before he has a chance to use Battle Trance or a Black King Bar.

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Single-target disablers will have difficulty locking down a Chaos Knight with Phantasm active: Bane, Beastmaster, Bloodseeker, Clockwerk, Doom, Shadow Shaman.

* Chaos Knight's multiple illusions from Phantasm can destroy Undying, as Soul Rip can't offset the damage from the high amount of damage from his illusions.

* Illusion heroes, such as Naga Siren, Phantom Lancer, Chaos Knight, Terrorblade will become strong against Tinker in the late game when Tinker's only area of effect damage, March of the Machines, ceases to kill illusions quickly. Without Aghanim's Scepter Tinker is forced to defensively disarm heroes with Laser, leaving illusions free to deal physical damage which Tinker's low armor makes highly effective. In addition, Mjollnir or Battle Fury, two common pickups against illusion heroes, don't work well on Tinker at all.

* Heat-Seeking Missile allow easy Spiked Carapace stuns.
* As a fragile hero that relies on mana and intelligence items, Tinker is vulnerable to Mana Burn.
* Nyx Assassin's stuns can interrupt Rearm and leave Tinker helpless.
Additional:
* Nyx Assassin's whole skillset is good against Tinker:
* Impale prevents Tinker from blinding Nyx Assassin or fighting back, while giving Nyx' allies time to catch up to Tinker's position.
* Mana Burn generally deals more damage to intelligence based heroes like Tinker.
* Spiked Carapace can stun Tinker at a moment of Nyx Assassin's choosing if March of the Machines has been cast. It is also quite easy to time Spiked Carapace against Heat Seeking Missiles.
* Vendetta allows Nyx to approach Tinker in the trees or wait for him in common hiding spots and deal heavy damage to his low armor.

* Faceless Void's lack of strong area-of-effect spells makes it difficult for him to fight against Chaos Knight and his Phantasms.
* From a safe distance and if not caught, Chaos Knight can use Reality Rift to pull Faceless Void out of the Chronosphere which combined with Chaos Bolt can expose him to being bursted down by Chaos Knight's team before Void even succeeds to escape with Time Walk.

* Spiked Carapace stops Snapfire's Mortimer Kisses.

* Many of Nyx Assassin's abilities are good against Windranger.
* Impale is great for stunning Windranger and allowing additional disables to be landed.
* Mana Burn is useful against Windranger's decent intelligence growth and also burns some mana, preventing her from using more abilities.
* Spiked Carapace is easy to use against Powershot.
* Vendetta allows Nyx Assassin to sneak up on and deal massive damage to Windranger without giving Windranger a chance to use Windrun to evade it.
* Nyx Assassin's item build allows him to easily deal with Windranger.

* Spiked Carapace reacts on any of the damage over time from Phoenix's abilities and can interrupt Sun Ray and Icarus Dive.

* Spiked Carapace can stop Dawnbreaker's Solar Guardian which will eliminate her global presence and limits her movement around the map.
Additional:
* Spiked Carapace interrupts Starbreaker before Dawnbreaker has her Aghanim's Shard, as well as Solar Guardian during the initial channel, making her ineffective at joining and dealing damage in teamfights.
* The slow projectile and damage over time effect of Celestial Hammer makes it easy to stun Dawnbreaker if she attemps to engage or chase.

* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed Sanity's Eclipse and/or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used Black King Bar beforehand.
Additional:
* Outworld Destroyer's high mana pool and high intelligence makes him a prime target for Mana Burn.
* If timed correctly, Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.

* Vendetta can deal great damage against her. However, it requires an direct attack, so Nyx Assassin may have difficulties applying Vendetta on her.
* Enchantress's lack of mobility makes her a primary target for ganking with Vendetta.
* Spiked Carapace can reflect Impetus and stun Enchantress.
* Mana Burn can deal tremendous damage against her due to being an Intelligence hero.
Additional:
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.

* Illusory Orb is easy to reflect with Spiked Carapace, either stunning Puck and setting up an easy Impale or forcing a premature Phase Shift.
* Puck is an intelligence hero that tends to build intelligence items, making it vulnerable to Mana Burn.
* An ill-timed Phase Shift can easily set Puck up to be stunned by Impale.
* Puck's low base armor and below average agility gain mean it is always susceptible to Vendetta.
Additional:
* Nyx Assassin can take advantage of every one of Puck's weaknesses. His entire skill set is very effective in countering Puck.
* Because Illusory Orb is such a slow moving projectile, Nyx Assassin can simply walk into the orb and activate Spiked Carapace, stunning Puck and setting up an easy Impale. This can be circumvented by using Phase Shift while the orb is traveling, however, that means that Puck cannot use Phase Shift to dodge any other skill nor use it to safely blink away from a fight.
* Puck is an intelligence hero that likes to build intelligence items such as Eul's Scepter of Divinity, Scythe of Vyse, and Dagon. This makes Mana Burn that much more deadly against Puck.
* An ill-timed Phase Shift can turn into an easy setup for Impale.

* Mana Burn can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.
* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with Spiked Carapace.

* Level 20 talent allows Reality Rift to bypass spell immunity provided by Rage, thus negating the advantage Lifestealer has in his kit.
* The fact that Lifestealer lacks wave clearing and reliable lockdown makes it difficult to fight Chaos Knight's illusions.
* Feast is largely negated by Chaos Knight's high burst damage from Chaos Strike.
Additional:
* Chaos Strike is a strong burst damage passive that allows Chaos Knight to stand up and even survive Lifestealer's attacks. Level 20 Talent: Reality Rift Pierces Spell Immunity allows him to burst down Lifestealer even while he is in Rage.
* Lifestealer's single-target nature will struggle against Chaos Knight's Phantasm illusions and will be forced to itemize for them.

* Heroes with illusion and clone abilities may confuse Bloodseeker, causing him to waste time in fights: Phantom Lancer, Chaos Knight, Arc Warden

* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* While Blade Fury is on cooldown, Juggernaut can be easily killed by a standard Chaos Bolt & Reality Rift combo.
* Phantasm illusions can tank Omnislash.

* Phantasm dispels Track, and the illusions make it difficult to Track the real Chaos Knight.
* Bounty Hunter is fragile and can easily be killed by Chaos Knight and Phantasm's illusions.

* Phantasm gives Chaos Knight a significant advantage against single-target damage dealers: Lifestealer, Wraith King, Night Stalker, Troll Warlord.

Additional:
* Chaos Bolt can stun Night Stalker outside of Crippling Fears relatively small radius.
* Reality Rift is a great way to force Night Stalker to fight Chaos Knight, a hero with massive health and damage output. It also forces Night Stalker's Crippling Fear off his primary target.
* Night Stalker doesn't have a lot of ways to deal with multiple targets, which makes him vulnerable to Phantasm illusions unless Night Stalker buys Aghanim's Scepter.