* Heroes who can provide constant vision inside the Roshan Pit can negate one of the strongest advantages of Ursa, which is the possibility of quickly killing Roshan at the early game, with minimum itemization needed (Clockwerk, Beastmaster, etc).

* Heroes with high physical damage can damage Lifestealer more than he can heal: Bristleback, Clinkz, Luna,Shadow Fiend, Slardar, Terrorblade

* Enemies that possess high defenses through magic resistance, damage reduction, or high regeneration will make it difficult to whittle their health down to get to Reaper's Scythe's threshold. Such heroes include Bristleback (although only from behind), Spectre, Ursa, and Dragon Knight.

* Some heroes with extreme range, like Zeus, Invoker or Clockwerk, can snipe your allies from anywhere after your Grave has expired.

* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with Hookshot) can easily avoid Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.

* Battery Assault, Power Cogs, and Hookshot can interrupt Freezing Field, the latter two being able to go through invisibility should Crystal Maiden use Glimmer Cape.
* Rocket Flare can be used to find Crystal Maiden should she try to hide in the trees to try to safely cast Freezing Field.
* Hookshot allows Clockwerk to easily close in on Crystal Maiden and kill her.

* Viscous Nasal Goo can hinder Crystal Maiden's already abysmal mobility, which allows Bristleback (or his teammates) to run her down and kill her.
* Bristleback frequently builds Blade Mail, which can quickly kill Crystal Maiden if her ultimate is used while he is under its effect.
* The passive part of Bristleback will trigger many, many times under the damage from Freezing Field, and as the stacks increase, the damage output from each successive cast (or proc) will eat away at Crystal Maiden's small HP pool.

* Meat Hooking a Clockwerk can backfire for Pudge, as Battery Assault and Blade Mail will hurt Pudge more than he hurts Clockwerk.

* Bristleback is one of the hardest heroes to gank with a Meat Hook and Dismember combo, and attempts to do so sometimes backfire on Pudge.
Additional:
* Pudge is particularly susceptible to Bristleback's Viscous Nasal Goo and Quill Spray due to his naturally low armor and poor agility gain.
* Bristleback, in combination with his strength gain, high health, common itemization for magic resistance and damage reduction from Bristleback makes him a poor target for Pudge.

* Power Cogs prevent Windranger from fleeing with Windrun.
* Battery Assault repeatedly interrupts Focus Fire, disrupting Windranger's damage output.
Additional:
* Windranger cannot escape with Windrun when she is trapped inside Power Cogs.
* Battery Assault repeatedly interrupts Focus Fire, disrupting Windranger's damage output.

* Combo Quill Spray and items Blade Mail can easily trigger from Focus Fire damage.
Additional:
* Using Focus Fire on Bristleback tends to fare badly for Windranger, as he can trigger passive Quill Sprays many times, especially when she attacks him from behind. In addition, Windrun does not protect her from both Viscous Nasal Goo and Quill Spray, rendering her helpless.
* Bristleback's natural tankiness makes it hard for Windranger to effectively burst her down throughout the game.
* Bristleback tends to continuously spam Viscous Nasal Goo to slow down Windranger when she uses Windrun to escape, potentially allowing him to outrun her with his Warpath stacks.
* Bristleback can build Lotus Orb to reflect Shackleshot and Focus Fire back at Windranger.

* Black Hole requires channelling, making it easy to be interrupted with Hookshot.
* Enigma lacks mobility without a Blink Dagger and also is squishy, making him fall easily when ganked by Clockwerk.
Additional:
* Hookshot's stun pierces through spell immunity and Enigma's channeling can be easily cancelled from a safe distance, assuming none of his allies are in the way, and the Black Hole is not centered directly on Enigma.

* Bristleback's constant harass from Quill Spray will greatly hurt Enigma's laning and kill his Eidolons.
* However, Bristleback has no way of canceling Black Hole at all. And Bristleback is not a hero that goes for disabling items to counter that problem.

* Clockwerk's long range initiation and catch makes it incredibly difficult for Nature's Prophet to split push and show on the map alone.
* Rocket Flare can be used to scout Nature's Prophet if he is hiding in the forest, and can provide vision inside of Sprout.

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* Quill Spray usually hits Meepo's clones, although Bristleback cannot turn his back when rooted with Earthbind.

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* Heroes with damage-over-time abilities easily allow Bristleback to turn his back in order to proc Bristleback continuously and to massively reduce to damage dealt to him: Arc Warden, Venomancer, Luna.

Additional:
* Quill Spray and Bristleback harass Luna more efficiently than she does with Lucent Beam.
* Bristleback helps return a lot of damage to Luna’s team if she uses her nukes on him and he has his back to her.
* Viscous Nasal Goo and Warpath are enough to outrun a speedy Luna.
* Bristleback tends to be a frequent carrier of Crimson Guard and Eternal Shroud, which are good protection from Moon Glaives and Eclipse.
* For the same reasons, Bristleback makes a very powerful ally for Luna when they are in the same team.

* Power Cogs pushes Monkey King out of Wukong's Command, ending his ultimate.
* Rocket Flare allows Clockwerk to scout Monkey King in the trees, and chase him with Hookshot.

* Viscous Nasal Goo slows down Dragon Knight and lowers armor, locking him down and making him more vulnerable.

* Clockwerk is also the least optimal target for Sniper to attack in a teamfight, although more experienced players will rarely make this mistake.
* With no mobility or disable skills, getting trapped in Power Cogs is a death sentence for Sniper.

* Tiny's nonexistent armor in the early game makes him very vulnerable to Quill Spray's large amounts of physical damage.
* Bristleback decreases Tiny's high burst damage against Bristleback.
* Viscous Nasal Goo can slow Tiny to a crawl and allows Bristleback to easily kite him with his high movement speed and Quill Spray's long range, as Tiny has no ability to escape.

* Lycan's wolves deal little damage to Bristleback, and are easily killed by Quill Spray, even when they're invisible.
* Lycan's lack of burst damage makes it very hard for him to kill Bristleback, especially when his back is turned.
Additional:
* Quill Spray can be used to kill Lycan's summons.
* Bristleback allows him to stay alive against Lycan while dishing out counter attacks
* He can overpower Lycan with his Warpath instead.

* Bristleback's abilities are nearly useless for Rubick to Spell Steal, as he does not gain the bonuses from Warpath.
Additional:
* Rubick deals little damage on his own, and Bristleback can simply shrug off all his spells and chase Rubick down with his Quill Spray and the damage bonus from Warpath.
* Rubick does not tend to charge forward in teamfights, stay in the front lines under most circumstances, yet effective casts of Quill Spray and Viscous Nasal Goo requires the opposite as they require multiple casts and close range to add up stacks.
* Rubick does not benefit from Warpath through casting the stolen spell.

* Pugna's squishiness and lack of mobility make him easy prey for a Hookshot initiation.
* Clockwerk's high health, low mana costs, and lack of reliance on Blink Dagger make Nether Ward ineffective.
* Battery Assault shuts down Aghanim's Scepter upgraded Life Drain, as the repeated ministuns prevent Pugna from channeling for an extended length of time.
Additional:
* Clockwerk loves to Hookshot low health, immobile targets like Pugna.
* Pugna's Life Drain gets immediately and repeatedly (if an Aghanim's Scepter was purchased) cancelled due to Battery Assault, especially if Pugna is trapped inside Power Cogs.
* Clockwerk also loves to build Blade Mail, which will deal more damage to Pugna than Clockwerk due to Pugna's low health pool.
* Finally, both Hookshot and Rocket Flare can allow him to finish off Pugna out of range of his Nether Ward.

* Power Cogs keeps Primal Beast pinned down, preventing him from doing damage with Trample. Primal Beast's slow attack speed makes it hard for him to break the cogs and get away. In addition, Power Cogs' knockback is forced movement and thus will intercept Primal Beast's Onslaught if placed well.
* Battery Assault on a lone Primal Beast in the early game effectively keeps him from winding up Onslaught or basic attacking.
* Rocket Flare and Jetpack (from purchasing Aghanim's Shard) give Clockwerk many options to scout for Primal Beast, whose kit benefits greatly from ambushing.

* Getting trapped in Power Cogs usually means the end for Drow Ranger.
Additional:
* Hookshot lets Clockwerk close the gap to Drow Ranger, disabling her Marksmanship bonus.
* Power Cogs and Battery Assault keep Drow Ranger from escaping.
* Power Cogs and Battery Assault also keep Drow Ranger close, nullifying Marksmanship.

* Quill Spray will hit Riki even when he is invisible.
* Cloak and Dagger's bonus backstab damage is rendered irrelevant against Bristleback.
* Smoke Screen does not stop Bristleback's passive from activating.
* Due to Bristleback's natural tankiness, he is an ideal Gem of True Sight carrier, directly countering Riki's invisibility.
Additional:
* The bonus Backstab damage from Cloak and Dagger is rendered irrelevant with Bristleback and hurts Riki more than him because of the passive Quill Spray.
* Riki can still get damaged by Bristleback's Quill Spray while invisible, and it can be hard to deal with in lane.
* Bristleback is not too bothered by Smoke Screen. Though he cannot use Quill Spray manually inside it, it still procs passively when he takes damage from the back. The movement speed from Warpath allows him to get out of the area easily.
* Due to Bristleback's natural tankiness, he is an ideal Gem of True Sight carrier.
* Riki rarely buys Silver Edge to break Bristleback's passive because the invisibility aspect of it is redundant.

* Clockwerk can use Power Cogs to repel Spirit Breaker when he charges in with Charge of Darkness.
* Spirit Breaker's slow 0.6 second attack animation attacks do little damage against Clockwerk. It can also constantly be interrupted by Battery Assault.
* Nether Strike's 1.2 second charge time gives Clockwerk plenty of time to activate Blade Mail and for Battery Assault to cancel it.
Additional:
* Battery Assault will continuously prevent Spirit Breaker from using Nether Strike, Charge of Darkness and even right clicking because of his slow base attack speed.

* Heroes who can continue dealing damage even while being stunned: Luna, Razor, Axe, Bristleback, Leshrac, Death Prophet, Jakiro.

* Quill Spray's constant AoE damage will hit Dark Willow even in Shadow Realm. Its automatic damage will hurt her if she tries to get close and use Bedlam.

* Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.

* Clockwerk's Battery Assault disables Earth Spirit's Rolling Boulder, while his Power Cogs ensure, that Earth Spirit can't move away from it.
* His Hookshot allows him to chase after Earth Spirit, while using Rocket Flare to gain vision.

* Battery Assault will continuously interrupt Earthshaker's long cast animations.
* Power Cogs can also trap Earthshaker after he initiates.
Additional:
* Battery Assault interrupts Earthshaker's long cast animations, preventing him from using any abilities apart from Echo Slam.
* Power Cogs often separate the battlefield so that both enemies and allies are unlikely to cluster.
* Rocket Flare allows Clockwerk to scout Earthshaker before a fight starts and potentially cancel his Blink Dagger.
* Hookshot enables Clockwerk to catch Earthshaker before he gets a chance to initiate a fight.

* Battery Assault easily interrupts Centaur Warrunner due to his poor cast animation.
* Power Cogs can negate Stampede.

* Quill Spray will hit Sand King inside Sand Storm, damaging him and putting Sand King's Blink Dagger on cooldown, preventing him from escaping.
* Epicenter's numerous damage ticks will trigger Bristleback's passive repeatedly during teamfights.

* Lone Druid and The Spirit Bear cannot burst down Bristleback due to Bristleback
* Bristleback can easily run to Lone Druid without any hesitation, with Viscous Nasal Goo to reduce armor and slow the Spirit Bear or Lone Druid and Quill Spray can deal damage to both Lone Druid and the Spirit Bear at the same time

* Battery Assault's continuous mini-stun makes it hard for Elder Titan to cast his spells due to his poor cast animation.
* Elder Titan's channelling with Echo Stomp makes a good setup for Hookshot if timed correctly.

* Arc Warden has relatively lower armor and mobility, which makes him an easy target to apply Quill Spray and Viscous Nasal Goo stacks.
* Arc Warden also does not like to build a Silver Edge as it takes a long time to build up and may slow down the timings for other important items needed in the game like Gleipnir.
* However, do note that in a game where Arc Warden's team has many jumping capabilities or good passives, like a Tidehunter or Spectre, a Silver Edge becomes incredibly valuable on Arc Warden as not only can he run away from the jumps, he effectively gets 2 breaks, and Bristleback may not be the best pick.

* Fortune's End cannot dispel Warpath stacks on Bristleback or Quill Spray stacks on allies.
* Bristleback can heavily reduce Oracle's damage output. With it, Oracle may accidentally heal Bristleback with Purifying Flames, especially if Bristleback has bonus magic resistance.

* Rocket Flare can find Tinker if he blinks into the treeline, and Hookshot will prevent him from teleporting out.
* Battery Assault makes Tinker unable to Rearm by stunning him repeatedly.
Additional:
* Clockwerk can easily catch a split pushing Tinker with his Hookshot and prevent him from escaping with Power Cogs and Battery Assault. Clockwerk can also find a Tinker hiding in trees with his Rocket Flare.
* Clockwerk usually buys a Blade Mail, which does lots of damage to Tinker if he gets hit by his abilities (especially March of the Machines).

* Heroes with damage-over-time abilities easily allow Bristleback to turn his back in order to proc Bristleback continuously and to massively reduce to damage dealt to him: Arc Warden, Venomancer, Luna.

* Heroes with nukes that can jump her: Clockwerk, Snapfire, Spirit Breaker, Techies

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

* Axe, Bristleback, Centaur Warrunner, Spirit Breaker, Pudge, Huskar, Wraith King, Doom: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

Additional:
* Battery Assault prevents Jakiro from casting spells as all his spells have very long cast times.
* Jakiro is also an easy target for Clockwerk's Hookshot + Power Cogs combo, as he has little mobility and no escape without items.
* Alternatively, if the enemy Clockwerk traps one of his own allies or Jakiro's allies in the cogs, it gives Jakiro an ideal setup to punish Clockwerk and his ally or to save Jakiro's ally, respectively.

* Macropyre's frequent damage ticks causes Bristleback to activate repeatedly, resulting in free damage as long as Bristleback faces away from Jakiro.

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

Additional:
* Clockwerk naturally builds Blade Mail, reflecting Leshrac's high magic damage output back at him.
* Power Cogs will prevent Leshrac from reaching Clockwerk's team and dealing large AOE damage to them.
* Power Cogs will also keep Leshrac close, wasting his Diabolic Edict on just Clockwerk.
* Battery Assault interrupts Leshrac's long cast times of Split Earth and Lightning Storm.

* Bristleback's Viscous Nasal Goo can catch and slow Bounty Hunter. Warpath and Quill Spray can defeat him quickly due to his small HP pool when compared to Bristleback's.

* Heroes who can stun Sven even with an activated Black King Bar can be an issue: Clockwerk, Beastmaster.

* Heroes who can stop Axe from getting close will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Heroes who can stop Axe from getting close will severely inhibit his presence in fights: Bristleback, Crystal Maiden, Batrider, Arc Warden, Winter Wyvern, Clockwerk

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Quill Spray quickly destroys Chaos Knight's Phantasms.

* Quill Spray destroys spiderlings, and hits Broodmother even when she's regenerating in her webs. This makes Bristleback one of her hardest counters in lane.
Additional:
* Bristleback reduces most of Broodmother's and her spiderlings' damage.
* Quill Spray will hit any spiders in its proximity, hindering Broodmother's fighting and farming capabilities.

* Bristleback's tankiness and damage reduction from the rear makes him very hard for Phantom Lancer to chase and finish off, due to his lack of burst damage.
* Quill Spray quickly destroys Phantom Lancer's illusions.
* Bristleback's passive costs no mana, meaning that it will continue to trigger even if Phantom Lancer drains Bristleback's mana with Diffusal Blade.
Additional:
* Bristleback's tankiness and damage reduction from the rear makes him very hard for Phantom Lancer to chase and finish off, due to his lack of burst damage.
* Quill Spray destroys Phantom Lancer's illusions.
* Bristleback's passive costs no mana, meaning that it will continue to trigger even if Phantom Lancer drains Bristleback's mana with Diffusal Blade.

* The damage from Burning Spear can be reduced by turning away from Huskar.
* Bristleback can bait Huskar into using Life Break on him, then turn around and receive very little damage.
Additional:
* Bristleback's tankiness and Bristleback allow him to outlast Burning Spears' damage-over-time at almost any point in the game. In addition, if Huskar chooses to cast Life Break on Bristleback, Bristleback can simply turn around before it hits and receive little damage.
* Viscous Nasal Goo will reduce Huskar's low armor even further, and Quill Spray and Warpath will tear him down extremely quickly.

* Battery Assault's mini-stuns can severely disrupt Legion Commander's attack animation when she enters a Duel, potentially saving Clockwerk (or his allies) and possibly even giving him an edge in securing a win himself.
* Power Cogs pushes Legion Commander away from Clockwerk's allies when she enters a Duel.