* Grave Chill will make Crystal Maiden's bad movement speed even worse.
* Soul Assumption charges can easily be stacked up from Freezing Field, allowing Visage to nuke enemies multiple times throughout the fight.
* {U:Familiar}'s Stone Form can also be used to interrupt Freezing Field, even while Crystal Maiden is under the effects of Glimmer Cape. Crystal Maiden must purchase a Black King Bar, which is far more costly.

* Even though Visage's Familiars from Summon Familiars are fragile and can be killed quickly with Nyx Assassin's high burst damage, they can deal many instances of damage quickly, minimizing the effectiveness of Spiked Carapace.
* Gravekeeper's Cloak and tanky item builds make Visage hard for Nyx to kill with his burst damage. Aghanim's Shard upgraded Gravekeeper's Cloak also allows Visage to use Stone Form to both recover himself and stun Nyx Assassin if he is close enough to Visage.
* Visage's long range on Soul Assumption and Grave Chill make him hard to escape from, and Soul Assumption's low cooldown outmatches Spiked Carapace.

* Lucent Beam allows Luna to easily cancel Freezing Field.
* Without Black King Bar protection, Lucent Beam and Eclipse can make a short work out of Crystal Maiden's abysmal health.
* Skilled Luna will always buy Dust of Appearance, allowing her team to have a vision on Crystal Maiden while invisible and during channeling Freezing Field.
* Even with Black King Bar, Luna can still inflict considerable damage on Crystal Maiden with her attacks, which get empowered with Moon Glaives and Lunar Blessing, also smart and skilled Luna will buy Abyssal Blade to cancel Freezing Field even through Black King Bar in case of emergency. And since Crystal Maiden rarely buys Linken's Sphere, this can be a very big problem for her.
Additional:
* Lucent Beam allows Luna to easily cancel Freezing Field.
* Without Black King Bar protection, Lucent Beam and Eclipse can make a short work out of Crystal Maiden's abysmal health.
* Skilled Luna will always buy Dust of Appearance, allowing her team to have a vision on Crystal Maiden while invisible and during channeling Freezing Field.
* Even with Black King Bar, Luna can still inflict considerable damage on Crystal Maiden with her attacks, which get empowered with Moon Glaives and Lunar Blessing, also smart and skilled Luna will buy Abyssal Blade to cancel Freezing Field even through Black King Bar in case of emergency. Forcing Crystal Maiden to buy Linken's Sphere.

* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Additional:
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.

* Duel is a great initiation to target Crystal Maiden with, as it prevents her from using Freezing Field or any other abilities and allowing the enemy team to quickly kill her before she can aid her team in a fight.

* Duel's long duration prevents Nyx Assassin escaping from Vendetta. With Aghanim's Scepter, she can also bypass Spiked Carapace.

* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.

* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and fighting back with Spiked Carapace.
* Doom's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off.

* Crystal Maiden's already low armor and easily interruptible ultimate, Freezing Field can make Slardar her worst nightmare. Crystal Maiden also often builds Glimmer Cape which is revealed by Corrosive Haze.

* Corrosive Haze hinders Nyx Assassin's ganking attempts with Vendetta, as well as reducing his armor and make him very vulnerable due to his low health pool.

* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of his abilities without a Black King Bar.
* With the Aghanim's Scepter upgraded Macropyre, Black King Bar becomes nearly useless for Crystal Maiden, as its high pure damage over time, long duration and ability to pierce spell immunity will either force Crystal Maiden to forcefully cancel Freezing Field or even discourage her from using it at all.
Additional:
* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of Jakiro's abilities without a Black King Bar.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, making Black King Bar nearly useless for Crystal Maiden, as its high damage over time and long duration can discourage Crystal Maiden to use Freezing Field. Remember, however, that Crystal Maiden can partially solve this issue by buying Aghanim's Shard, which will allow her to simply walk out of Macropyre.

* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.

* Mirror Image can dispel Frostbite.
* Song of the Siren can stop Freezing Field regardless of any kind of invisibility as well as allow Naga Siren's team to quickly close the gap on Crystal Maiden.
* With Aghanim's Scepter, Naga Siren can get access to Reel In ability, which can allow her to pull Crystal Maiden toward herself and her team and cancel Freezing Field even through Black King Bar.
Additional:
* Mirror Image can dispel Frostbite.
* Song of the Siren can stop Freezing Field regardless of any kind of invisibility as well as allow Naga Siren's team to quickly close the gap on Crystal Maiden.
* Ensnare allows Naga Siren and her team to quickly catch up with Crystal Maiden and kill her.
* With Aghanim's Scepter, Naga Siren can get access to Reel In ability , which can allow her to pull Crystal Maiden toward herself and her team and cancel Freezing Field even through Black King Bar.

* Nyx Assassin's skillset is mostly single-targeted, therefore he will have difficulties against heroes with illusions and summons: Naga Siren, Broodmother, Lycan, Visage, Phantom Lancer. And to make things worse, Nyx Asassin is not a common Battle Fury, Maelstrom, Mjollnir, Gleipnir or Radiance wielder to counter this problem.

* Juggernaut and Lifestealer have abilities (Blade Fury and Rage respectively) that prevent Crystal Maiden from using her spells on them in the early game, before Black King Bar and other magical reduction is even an issue.

Additional:
* Crystal Maiden is an ideal target for Lifestealer due to her poor mobility and low health pool. Lifestealer can usually catch up to her simply by casting Rage, as none of her abilities pierce through magic immunity. Freezing Field can potentially make her even more vulnerable to Lifestealer while under Rage as she is even more immobile while channeling it.
* Lifestealer commonly buys Abyssal Blade, which allows him to cancel Freezing Field, even if Crystal Maiden is spell immune.
* Alternatively, Aghanim's Scepter upgraded Infest combined with Abyssal Blade and with items that provide attack speed which Lifestealer commonly buys allow him to to cancel Freezing Field from within the Crystal Maiden.

* Like with Juggernaut's Blade Fury, Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if Vendetta is on cooldown. Nyx Assassin cannot counter Rage with Spiked Carapace because Rage gives Lifestealer spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
* Open Wounds from Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with Dust of Appearance or a Gem of True Sight. And similarly to Juggernaut's Omnislash and Swiftslash from Aghanim's Scepter, Aghanim's Scepter upgraded Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. and Nyx Assassin cannot counter this with Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
* Like with Juggernaut, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.

* Heroes who can easily harass Crystal Maiden out of lane in the early game (Clinkz, Viper) can prevent Crystal Maiden from being able to level effectively, and can ultimately slow down her level 6, 12, and 18 to a point where enemy carries already have items to address her ultimate.

* Corrosive Skin minimizes the damage from Impale and Mind Flare.
* Nyx Assassin cannot survive several poison damage-over-time, even Spiked Carapace is activated.

* Juggernaut and Lifestealer have abilities (Blade Fury and Rage respectively) that prevent Crystal Maiden from using her spells on them in the early game, before Black King Bar and other magical reduction is even an issue.

* Blade Fury makes Juggernaut immune to all Nyx's abilities, except Vendetta.
* Omnislash. and Swiftslash can burst Nyx down, ignoring Spiked Carapace. However, Vendetta can be used to escape, canceling Omnislash/Swiftslash.
Additional:
* Juggernaut's entire skillset greatly counters Nyx Assassin's Spiked Carapace, his most important ability.
* Blade Fury allows Juggernaut to freely attack Nyx Assassin, and deal heavy damage to Nyx Assassin. Nyx Assassin cannot counter Blade Fury with Spiked Carapace because Blade Fury gives Juggernaut spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Juggernaut while he is spell immune.
* Healing Ward allows Juggernaut to recover himself and his allies from Nyx Assassin's damage output.
* Omnislash and Swiftslash from Aghanim's Scepter can quickly finish off Nyx Assassin, and just like Blade Fury, Nyx Assassin cannot counter neither Omnislash and Swiftslash from Aghanim's Scepter with Spiked Carapace because both abilities render Juggernaut invulnerable. And if Nyx Assassin has no Vendetta available to use for escaping, both abilities will kill him very quickly before he can do anything.
* Overall, any attempt for Nyx Assassin to gank and kill Juggernaut will hurt Nyx Assassin more than Juggernaut.

* Heroes with low mobility that rely on spells: Zeus, Lina, Crystal Maiden.

* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.

* In general, heroes with AoE or long range disables (such as Faceless Void with Chronosphere, Pudge with Meat Hook and Elder Titan with Echo Stomp) hinder Crystal Maiden, preventing her from using Freezing Field to help her team in a fight.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Lycan's high health allows him to easily shrug off Nyx Assassin's burst damage and fend him off.
* As Lycan commonly buys Black King Bar, he can use it to freely attack Nyx Assassin and chase after him with Shapeshift.

* Low mobility heroes: Heroes with no/little means of traveling fast have difficulty getting to/away from Bounty Hunter due to his slowing Jinada and hastening Track. Few examples of such heroes are: Crystal Maiden, Sniper, Ursa, Witch Doctor, etc.

Additional:
* Shuriken Toss's stun is useful for cancelling Freezing Field from a distance.
* Track can be used for revealing Crystal Maiden when she uses Glimmer Cape.
* Jinada does burst physical damage (which is even bigger if dealt under Track's crits), which is effective due to Crystal Maiden's low HP and armor.
* Bounty Hunter likes to stay hidden from the fight and is less likely to get caught by Crystal Maiden's spells.

* Nyx Assassin wants to start ganking as soon as he gets his Vendetta. Keeping him Tracked prevents him from ganking, and thus from doing his job in the game.
* Nyx Assassin has a lot of armor and health regen, making the nuke damage from Shuriken Toss very good against him.
Additional:
* Track hinders Nyx Assassin's ganking attempts with Vendetta, making him an easy kill for gold as well.

* Phantom's Embrace can silence Crystal Maiden and disrupt Freezing Field's channeling. Her slow movement speed and fragile nature will also make her an easy target for Stroke of Fate and Ink Swell.

* Centaur's low Intelligence makes Mind Flare do low damage.
* With some creative skill builds, Centaur's Hoof Stomp stun duration should always last longer than Spiked Carapace stun, so escaping unscathed is hard for Nyx.
* With Blink Dagger and detection, Centaur can devastate Nyx in the open.
* However, bear in mind that Nyx can also easily initiate on Centaur Warrunner as well if he uses Spiked Carapace in anticipation, and with Vendetta. The damage from Retaliate will be reflected back to Centaur Warrunner, stunning him with no chance to react after he's revealed himself, and should guarantee a successful Impale.

* Viscous Nasal Goo can hinder Crystal Maiden's already abysmal mobility, which allows Bristleback (or his teammates) to run her down and kill her.
* Bristleback frequently builds Blade Mail, which can quickly kill Crystal Maiden if her ultimate is used while he is under its effect.
* The passive part of Bristleback will trigger many, many times under the damage from Freezing Field, and as the stacks increase, the damage output from each successive cast (or proc) will eat away at Crystal Maiden's small HP pool.

* Cyclone from Storm in Primal Split can waste Nyx's Spiked Carapace, since its duration is shorter than the Cyclone's.

* Boulder Smash and Geomagnetic Grip allow Earth Spirit to easily disrupt Freezing Field, regardless of where Crystal Maiden is due to their incredible range. Earth Spirit is quite possibly the best hero for stopping long channeling abilities, and Crystal Maiden is vulnerable to him without a Black King Bar.
* All of Earth Spirit's spells allow him to easily close in on Crystal Maiden and kill her. Since she is a low health support, she generally stays behind in teamfights, but Earth Spirit can easily close the distance.
* Crystal Maiden has low movement speed and no other escape mechanism, rendering her extremely vulnerable to Earth Spirit's arsenal of long-range, damaging spells.

* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If Frostbite has already been used, Mirana can Leap away even when slowed by Crystal Nova or Freezing Field.

* Crystal Maiden will be not able to cast her Freezing Field while being constantly stunned by Enigma's Malefice.
* Enigma's Black Hole can cancel Freezing Field's channeling regardless of her Glimmer Cape and Black King Bar.

* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.

* Battery Assault, Power Cogs, and Hookshot can interrupt Freezing Field, the latter two being able to go through invisibility should Crystal Maiden use Glimmer Cape.
* Rocket Flare can be used to find Crystal Maiden should she try to hide in the trees to try to safely cast Freezing Field.
* Hookshot allows Clockwerk to easily close in on Crystal Maiden and kill her.

* Snowball allows Tusk to easily cancel Freezing Field from a safe distance without putting himself in any danger.
* Walrus PUNCH! is most certainly a high enough damage nuke to easily kill off Crystal Maiden.
* Ice Shards can prevent the already immobile Crystal Maiden from escaping, making her an easy kill for either Tusk or a teammate.
Additional:
* Crystal Maiden's low health and armor make her an easy target for Walrus PUNCH!
* Tusk's Snowball can protect allies and cancel Freezing Field.
* Snowball and Walrus PUNCH! can interrupt Freezing Field.

* Dragon Knight's heavy armor negates Vendetta's burst physical damage. His large HP pool also gives him a good chance of surviving Nyx Assassin's follow-up nuke damage.

* Crystal Nova helps on farming while applies an area slow.
* Frostbite extends Rubick's lockdown duration while providing extra damage, also serves as a farming ability.
* Freezing Field deals much greater damage thanks to Arcane Supremacy in teamfights.
* Freezing Field is a channeling ability and therefore can be stolen easily.
* Crystal Maiden has no innate ability to interrupt Freezing Field, though it may not be the case for her teammates; Yet a well-times Telekinesis lift or drop can interrupt Freezing Field.
* Consider build items that strengthens Freezing Field, such as Aghanim's Shard, Black King Bar and Aghanim's Scepter to reach its full potential.

* Lone Druid's early game is good against slow, squishy supports since his bear is very strong early game and an Entangling Claws proc almost always guarantees a kill: Ancient Apparition, Crystal Maiden, Shadow Shaman, etc.

* Heroes with little health or magic resistance are easily picked off with Oracle's magic burst, such as Skywrath Mage, Crystal Maiden, or Enchantress.

* In general, heroes with AoE or long range disables (such as Faceless Void with Chronosphere, Pudge with Meat Hook and Elder Titan with Echo Stomp) hinder Crystal Maiden, preventing her from using Freezing Field to help her team in a fight.

* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.

* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: Lich, Crystal Maiden, Silencer, Keeper of the Light, Venomancer, etc.

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* Heroes with large health pools (Pudge) or good innate magic resistance (Anti-Mage) can be very problematic for Crystal Maiden, since even if they are under the effect of her ultimate for the entire duration, the damage output is simply not enough to kill or force them to retreat.

* Heroes who build mana boosting items but have low mana regeneration are especially vulnerable against Mana Break and Mana Void: Timbersaw, Slark, Shadow Fiend, Clinkz, Bristleback Nyx Assassin, Magnus

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* Heroes with very little to no area-of-effect abilities will struggle greatly against Broodmother: Sniper, Phantom Assassin, Nyx Assassin, Bane, Visage, Bounty Hunter.

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* Heroes with channeled abilities can be interrupted by a long-range Fissure: Crystal Maiden, Witch Doctor, Bane, Pugna, Pudge.

* Generally, any fragile heroes will have a hard time dealing with Undying's tankiness, and even more so if Decay is used on them. Some examples are Crystal Maiden and Witch Doctor.

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* Heroes with invisibility will be detected by Thirst when they have low enough health: Bounty Hunter, Templar Assassin, Riki, Clinkz, Weaver, Treant Protector, Nyx Assassin.

Additional:
* While Burrowing, Nyx is an easy target for a Blood Rite, although he can at least partially counter it with a well-timed Spiked Carapace.
* Thirst is always a threat to Nyx Assassin, hindering his attempt of escape using Vendetta.
* Rupture also prevents Nyx Assassin from escaping with Vendetta, as it forces him to stay still.

* Being a hero with low health and abysmal mobility, Lina can nuke her down easily.
* Since Crystal Maiden's Freezing Field is a channeled ability, Lina can use her Light Strike Array to cancel it easily.

* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.

* In the same vein, heroes with silences — especially with the AoE ones like Death Prophet's Silence — can also prevent Crystal Maiden from being able to impact a fight.

* In general, attacks of the melee heroes who are entirely reliant on dealing physical damage and/or have very little to no area-of-effect abilities will make Underlord tickle and will have no effect against him, and will be unable to ambush Underlord and his team if Underlord chooses to use Fiend's GAte to get to a designated point of the map: Phantom Assassin, Terrorblade, Troll Warlord, Drow Ranger, Phantom Lancer, Chaos Knight, Sven, Wraith King, Bounty Hunter, Alchemist, Templar Assassin, Nyx Assassin, Bane.

* Long range disables are really effective against dangerous area controllers and channeling Heroes, like Enigma, Faceless Void or Crystal Maiden, as it may cancel them or prevent enemies from doing further damage while keeping Lion in a relatively safe distance in the warzone.

* Some abilities deals damage from an independent source and not from the hero itself, so Nyx cannot counter them with Spiked Carapace: illusions or summoning units, Homing Missile, Nimbus, Mass Serpent Ward, Death Ward and especially Techies's mines.

* Fragile supports who die in a few hits against Sven's high physical damage: Crystal Maiden, Vengeful Spirit, Dark Willow.

* Crystal Maiden is extremely fragile and she's an easy target for him. She has no real disables that can lock Ember Spirit down, and all of her skill damage can be negated with Flame Guard. The damage from Searing Chains, Flame Guard, and Sleigh of Fist can easily take her down.

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* Impale and Spiked Carapace stun can be instantly dispelled by Aphotic Shield.
* Abaddon can use Borrowed Time and easily heal for the duration of Borrowed Time by Nyx's burst damage.

* As Crystal Maiden is squishy with very bad movement speed, Spectre can easily stay on Crystal Maiden with Haunt and Spectral Dagger.
* Late game, with enough farm, Spectre can withstand an entire Freezing Field, possibly even causing Crystal Maiden to kill herself from Dispersion.

* Smoke Screen effectively disables Crystal Maiden's channeling spell: Freezing Field.
* Due to her low health and armor throughout the game, Riki can kill her easily.

* Cold feet can be used to ensure that the full channel of Freezing Field doesn't go off.

* A well-timed Berserker's Call can expose Nyx Assassin while he is invisible with Vendetta, and prevent him from using Spiked Carapace.
* Axe can use Battle Hunger's damage over time to minimialize effects of Spiked Carapace.
* Axe's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off. Especially since Axe is a common Heart of Tarrasque wielder, which can completely eliminate any chance for Nyx Assassin to kill Axe alone.
* Culling Blade can often kill Nyx Assassin as he is very fragile and vulnerable to damage while Spiked Carapace is on cooldown.
Additional:
* A well-timed Berserker's Call can expose Nyx Assassin while he is invisible with Vendetta, and prevent him from using Spiked Carapace.
* Axe can use Battle Hunger's damage over time to minimialize effects of Spiked Carapace.
* Axe's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off. Especially since Axe is a common Heart of Tarrasque wielder, which can completely eliminate any chance for Nyx Assassin to kill Axe alone.
* Culling Blade can often kill Nyx Assassin as he is very fragile and vulnerable to damage while Spiked Carapace is on cooldown.

* Heroes with a low attack speed or are fragile will find themselves unable to deal with Troll Warlord's high physical damage and attack speed, like Crystal Maiden or Sven.

* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.

* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.

* Crystal Maiden's low health pool and slow movement speed make her a tempting and easy target.
* However, it may be wise to build Black King Bar first before attempting to fight her alone, as she can disable you and retaliate with Freezing Field.

* Puck has both Waning Rift and Dream Coil to stop Freezing Field's channel regardless of whether or not Crystal Maiden has a Glimmer Cape, as both spells fully affect invisible units.

* Heroes with a low health pool (Crystal Maiden, Skywrath Mage etc)

* Heroes with low health are especially vulnerable to Marksmanship's high damage output: Clinkz, Crystal Maiden.

* Heroes with channeled abilities which Assassinate may cancel at long range: Witch Doctor, Crystal Maiden, Shadow Shaman, Pugna

* Fragile supports with low armor are always a good prey, also her Psionic Trap will wear down most attempts to flee with their built-in disables: Silencer, Crystal Maiden, Warlock, Ancient Apparition, Grimstroke, Witch Doctor

* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.

* Heroes with slow movement speeds and small health pools (supports like Crystal Maiden or Witch Doctor) are easy targets for Phoenix. Should they be inflicted by its DOT debuffs, they will be very quickly killed without even getting a chance to fight back.

* Heroes with strong channeling spells like Crystal Maiden's Freezing Field, Bane's Fiend's Grip, and Enigma's Black Hole can easily be interrupted from a long range by Nether Swap, assuming they don't have a Linken's Sphere.

* Channeling heroes will not go well against Warlock, especially those who build Black King Bar as Warlock's ultimate ability stun goes through spell immunity. E.g.: Crystal Maiden, Witch Doctor, Enigma, etc.

* Heroes that have small health pools and little to no escape mechanisms are even easier prey for Necrophos. Ghost Shroud's slow will allow him to catch him with them, and get nuked down with his abilities, even preventing retaliation due to Reaper's Scythe's stun. Such heroes include Crystal Maiden, Witch Doctor, Warlock or Shadow Fiend.

* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, Enchantress, Gyrocopter, Lion, Riki, Techies, Terrorblade, Necrophos, Invoker.

* Heroes who rely on channeling abilities can be interrupted in teamfights by Rolling Thunder: Crystal Maiden, Pugna, Witch Doctor

* Gush can make Crystal Maiden's already weak armor even weaker.
* Kraken Shell can dispel Frostbite, preventing him from getting stuck inside Freezing Field.
* Ravage is very useful for interrupting Freezing Field, even while Crystal Maiden is under the effects of Glimmer Cape. Crystal Maiden must purchase a Black King Bar, which is far more costly.

* Even with Black King Bar or Linken's Sphere, Pudge's Meat Hook can still cancel Crystal Maiden's Freezing Field as she is a very easy target while channeling it.
* Pudge's Rot can make Crystal Maiden's already bad movement speed even worse.
* Many stacks of Flesh Heap will make it nearly impossible for Crystal Maiden to kill Pudge.
* Pudge's Dismember can also be used to cancel Crystal Maiden's Freezing Field, and alternatively, Pudge can also use it to save allies from getting killed by Crystal Maiden and heal them when upgraded with Aghanim's Shard.
* Crystal Maiden is prone to ganks in the lane or in the off-lane without proper vision. Pudge can take advantage of Crystal Maiden's lack of mobility, and gank her often.
Additional:
* Meat Hook can cancel Freezing Field, even if Crystal Maiden has Glimmer Cape.
* She is also slow and fragile, making her a good target for ganking.

* Any hero with low mobility and max healthsuch as Silencer, Crystal Maiden etc.

* Crystal Maiden is squishy, is heavily spell reliant, has low base Intelligence, and is naturally slow, making her an ideal target for Silencer.
* Crystal Maiden's Freezing Field has a similar cooldown to Global Silence, therefore, Freezing Field can almost always be canceled to ruin aggressive Crystal Maiden initiations.

* Nyx Assassin's skillset is mostly single-targeted, therefore he will have difficulties against heroes with illusions and summons: Naga Siren, Broodmother, Lycan, Visage, Phantom Lancer. And to make things worse, Nyx Asassin is not a common Battle Fury, Maelstrom, Mjollnir, Gleipnir or Radiance wielder to counter this problem.

* Heroes who can easily harass Crystal Maiden out of lane in the early game (Clinkz, Viper) can prevent Crystal Maiden from being able to level effectively, and can ultimately slow down her level 6, 12, and 18 to a point where enemy carries already have items to address her ultimate.

* Innately fragile heroes will die almost instantly to Reality Rift while Chaos Knight has illusions active: Drow Ranger, Bane, Necrophos, Crystal Maiden.