* Meepo lacks the disengages to escape a well-timed Echo Stomp, in particular if Elder Titan is his current target.
* Clones are counted as heroes, increasing massively the power of Astral Spirit's buffs, including Aghanim's Scepter's spell immunity buff.
* Meepo relies heavily on high agility and his mediocre strength gain makes him a very prized target for Natural Order.
* Meepo and his clones like to group up to hunt and kill in teamfights or ganks and can be easily disabled together with Echo Stomp.
Additional:
* Echo Stomp can completely disable multiple Meepos for 5 seconds.
* Astral Spirit will affect Meepo clones, as they don’t count as illusions. Elder Titan can receive a massive amount of damage, armor and movement speed from each Meepo.
* With Natural Order, Elder Titan’s mere existence causes Meepo to be disadvantaged, due to the aura that completely negates his base armor and magic resistance. Combining Astral Spirit with Natural Order allows Elder Titan to easily kill any Meepo within a second, depending on how much damage he gains from Astral Spirit.
* Earth Splitter deals over 30%/40%/50% of each Meepo’s max hp, and is even stronger if the Meepos are near Elder Titan due to Natural Order.

* Casting Bramble Maze on top of Meepo guarantees a root, as it is nearly impossible to leave the thorns with all of Meepo's clones.
* Terrorize and Cursed Crown offer great disables against the grouped Meepos and can prevent them from using Poof to escape.

* Morphling's high armor is primarily from morphing agility, which is reduced by Natural Order therefore making the hero very vulnerable when it has morphed a lot into agility.
* Morphling usually will Morph into high agility and low strength. This can be taken advantage of with a good stun or silence or by bursting him down before he has the time to Morph back to strength.
* Morphling is very vulnerable to Blade Mail under Natural Order and can easily burst himself down with his own auto-attacks or his magical damage combo.
Additional:
* Most of Morphling's armor comes from his high agility and it is reduced by Natural Order.
* However, the aura has only 350 range and Elder Titan can be bursted down by Morphling's nuke combo if he isn't careful.

* Terrorblade has a high base armor, and relies on many ultimate orb-based items (Manta Style and Eye of Skadi). Natural Order affects armor gained from agility, essentially reducing armor to zero if all armor is gained from agility. That effect combined with Terrorblade's low health can make a Elder Titan with an early value point in Natural Order a dangerous foe.
* Terrorblade's illusions are often grouped up in teamfight, making them more vulnerable to Echo Stomp.
Additional:
* Echo Stomp and Astral Spirit allow the enemy team to coordinate a kill on Terrorblade before he can Sunder.
* Natural Order cripples Terrorblade's armor that he crucially needs to survive due to his low strength gain.

* Terrorize, Bedlam and Cursed Crown ignores Pierce the Veil.
* Shadow Realm can be used to escape Pierce the Veil's high damage, as Muerta cannot attack her while she is in it

* Bramble Maze prevents Timbersaw from Timber Chaining away without getting rooted.
* Cursed Crown can still catch Timbersaw if he Timber Chains away.
* Reactive Armor offers little protection against Dark Willow's high magical damage.

* Astral Spirit can give Elder Titan a lot of damage and movement speed if Nature's Prophet sends all of his Treants together.
* Not only does Echo Stomp prevent Nature's Prophet from escaping using Teleportation, but Astral Spirit can be used to bypass Sprout and cancel Teleportation with it's own Echo Stomp from long distances.
* Earth Splitter can clear Nature's Prophet's Treants effectively.

* Terrorize forces Monkey King out of Wukong's Command.

* Terrorize forces Faceless Void out of Chronosphere.

* Bramble Maze will very likely catch Marci midair, disabling Marci's chasing/fleeing ability.
* Shadow Realm prevents Marci from bursting Willow down since she relies on physical attacks and unit target spells. With Aghanim's Scepter, Willow can hit Marci while Marci can't hit Willow.
* Bedlam and Eul's Scepter of Divinity allows Willow to manfight if Marci initiates with Rebound.
* Terrorize and Cursed Crown combo can waste Marci's ultimate for almost half of its duration.

* Bramble Maze stops Charge of Darkness in its tracks. Its very long duration means it can be used as an obstacle to block off an incoming Spirit Break during teamfights.
* Shadow Realm and Bedlam can be activated when Dark Willow sees Charge of Darkness coming, preventing Spirit Breaker from using Nether Strike after the initial stun.

* Windrun does not protect Windranger from Cursed Crown's stun or Dark Willow's magical nukes.
* Focus Fire cannot target Dark Willow in Shadow Realm and will be interrupted if targeted earlier, wasting the ultimate.
Additional:
* Windrun does not protect Windranger from Cursed Crown stun or Dark Willow's magical nukes.
* Focus Fire cannot target Dark Willow in Shadow Realm and will be interrupted if targeted earlier, wasting the ultimate.

* Bramble Maze greatly hinders Bloodseeker's ability to run around in teamfights and pick off dying allies.
* Shadow Realm prevents Bloodseeker from attacking dark Willow, allowing her to safely teleport away.

* Viper is an agility hero, and his item build mostly includes agility items, so Natural Order can be devastating, removing all armor and greatly decreasing the effectiveness of Corrosive Skin, weakening Viper's magic resistance. Additionally, Echo Stomp and Earth Splitter deal both magical and physical damage, and can help bringing Viper down fast.
* Aghanim's Scepter may be necessary to take Viper down due to Nethertoxin's break.

* Dark Willow's burst damage and stun prevents Troll Warlord from approaching her until he has Black King Bar.
* Troll Warlord's lack of burst damage makes it hard for him to kill Dark Willow before she slips into Shadow Realm.

* Phantom Lancer's lack of disables makes it hard for him to stop Echo Stomp's channelling.
* However, due to the long cast time of his abilities, a good Phantom Lancer can use Manta Style and/or Doppelganger to dodge the abilities.
* Phantom Lancer's high agility and relatively low strength make him very vulnerable to Natural Order.
* Additionally, Echo Stomp and Earth Splitter can clear his wave of illusions.
* Should Phantom Lancer tries to increase his health by investing for Heart of Tarrasque, Earth Splitter does more damage to him and his illusions.

* Natural Order aura prevents Slark from gaining armor from the agility stolen with Essence Shift.
* Echo Stomp and Earth Splitter can hit Slark through his Shadow Dance ultimate.
* Slark's stats gain is relatively low compared to most agility carries making him quite squishy without his agility-based armor.

* Elder Titan's Astral Spirit ability gives him bonus damage for each converted creep it passes through.
* Echo Stomp and Earth Splitter will often kill him or any of his allies quickly before he has time to use Hand of God.

* Echo Stomp can impede Broodmother's ability to push towers due to its low cooldown and long sleep duration.
* Astral Spirit can provide Elder Titan large amounts of damage, armor, and movement speed from her spiderlings.
* Natural Order negates Broodmother and her spiderling's base armor and magic resistance, increasing most damage dealt to them.

* Elder Titan's Natural Order completely nullifies Dragon Knight's high armor.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with powerful rooting abilities will disable most of Pangolier's skills, a bonus point if it pierces spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren

* Slow heroes that have a hard time escaping the Echo Stomp radius: Crystal Maiden, Pudge, Techies.

* In general, heroes with AoE or long range disables (such as Faceless Void with Chronosphere, Pudge with Meat Hook and Elder Titan with Echo Stomp) hinder Crystal Maiden, preventing her from using Freezing Field to help her team in a fight.

* Primal Beast really suffers against supports he cannot bully in the lane; this includes Dazzle, Shadow Demon and Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.