Enchantress
* Heroes with haste can negate Enchant's slow: 
Weaver, 
Dark Seer, 
Lycan, 
Centaur Warrunner.
Doom
* Whenever Doom casts his ultimate, Centaur Warrunner can cast Stampede and allow the 
Doomed hero to run away, wasting Doom's ultimate.
Additional:
* 
Stampede can be used to free an ally from the grasp of Doom. Without any means of effective lockdown, kills can be difficult to secure when against an enemy Centaur Warrunner. Also, Centaur's tendency to have lots of health and HP regen tend to help counter Doom.
Enchantress
* Heroes with break can disable Untouchable for a while: 
Doom and 
Shadow Demon (via 
Aghanim's Scepter), 
Viper, 
Shadow Shaman with Hex Breaks talent.
Doom
* The slow applied from 
Corrosive Skin offsets the movement speed bonus granted by Scorched Earth and the tick-based damage from Infernal Blade and Doom will continually slow Doom down. This allows Viper, much like Sniper, to 'kite' Doom and keep him at a safe distance between the two. Additionally, Corrosive Skin applies an attack-speed slow which is fairly crippling to a hero such as Doom that, naturally, has a high base attack-time, poor agility gain and builds little attack-speed items.
* Since Doom does not disable auto-cast abilities, Viper's 
Poison Attack will continue to work. Doom may find it hard to close the distance between himself and Viper, and thusly difficult to effectively lockdown and continually deal damage through his abilities.
Enchantress
* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.
Doom
* Heroes who often build 
Linken's Sphere: Weaver, 
Morphling, 
Medusa.
Doom
* Wraith King has three passive abilities and only a single active ability, so Doom does not hinder him significantly.
* Doom expires upon death, so it is effectively removed after 
Reincarnation activates.
Additional:
* Even if he is Doomed, Wraith King can tear down Doom with physical attacks, and can still reincarnate as long as it is off-cooldown.
Enchantress
* Enchantress's lack of area-of-effect abilities allows Broodmother to swarm her with Spiderlings.
* 
Spawn Spiderlings can kill enchanted creeps and create Spiderlings in their place.
* However, bear in mind that 
Untouchable makes it harder for Broodmother to actually hit Enchantress, even if Broodmother is spell immune. And Broodmother's only way to counter this is either by buying 
Silver Edge, buying items that deal high magical damage like 
Dagon, or by buying items that give high attack speed like 
Moon Shard.
Additional:
* Enchantress can be easily overwhelmed with Broodmother's spiderlings from Spawn Spiderlings and Enchantress can only control one of them with 
Enchant and she has no good waveclear (Spawn Spiderlings can also kill creeps controlled with Enchant).
* However, Untouchable's attack speed reduction can make it difficult for Broodmother to kill Enchantress even with any form of spell immunity.
Enchantress
* Enchantress has a very small health pool and cannot tank Lina's heavy magic burst.
* Untouchable is decently countered by 
Fiery Soul, exposing Enchantress's weakness to physical damage due to her low armor.
* Lina is decent at clearing creeps and can kill Enchantress's creeps quickly.
Additional:
* Enchantress has pitiful health, and cannot tank Lina's heavy magic damage.
* Untouchable is decently countered by Fiery Soul, exposing Enchantress's weakness to physical damage due to her low armor.
* Lina is decent at clearing creeps and can kill Enchantress' creeps quickly.
Enchantress
* Untouchable doesn't work against Unleash, as Marci gains 1000+ attack speed for the fury combo.
* Enchantress' low health makes her a fragile target for Marci's damage blasts.
* Marci can use Rebound on one of her enchanted creeps to easily reach the Enchantress and negate the bonus damage dealt by her 
Impetus. It helps that most of her best creeps have a low attack range, creating a makeshift bridge towards their master.
Enchantress
* 
Blade Fury dispels the slow from Enchant, and can burst Enchantress down during the laning stage.
* 
Omnislash and 
Swiftslash's physical damage burst ignore untouchable.
* Silver Edge is a common item for Juggernaut for dealing with Untouchable.
Additional:
* Blade Fury dispels the slow from Enchant, spell immunity and used to burst her down during the early laning stage.
* Omnislash and Swiftslash's physical damage burst ignore Untouchable.
* Silver Edge is an ideal item for Juggernaut to deal with Untouchable, making her vulnerable to melee attacks.
Enchantress
* 
Battle Trance and 
Fervor can help Troll Warlord deal with Enchantress through Untouchable.
Additional:
* Untouchable's attack speed slow is easily remedied by Fervor stacks and Battle Trance.
* Troll Warlord is a natural Silver Edge carrier, disabling Enchantress' Untouchable.
Enchantress
* Riki usually buys 
Diffusal Blade to initiate, which renders Enchantress' movement speed useless, and is usually followed with 
Smoke Screen.
* Riki can effectively hit Enchantress by 
Tricks of the Trade alongside with Diffusal Blade and Smoke Screen's initiation. For a hero like Enchantress, 3 to 4 hits from Riki is a big deal, unless Enchantress built 
Force Staff earlier.
Enchantress
* Amazingly, Enchantress has even lower health than Pugna. Though she does pack quite a punch through Impetus, she can't use it if she is under Decrepify.
* Pugna's Magical DPS is way greater than the heal from 
Nature's Attendants, which will also harm her quite a bit if she's next to Nether Ward.
Doom
* Due to Doom's naturally high health, strength gain and common itemization for durability, 
Heartstopper Aura is particularly effective. The health loss is also large enough that, throughout all stages of the game, the aura effectively neuters the health regeneration granted by Devour.
* Necrophos can help to keep both himself and his allies alive during Doom through his natural regeneration granted by Heartstopper Aura (which is not disabled by Doom), or in the case of an ally, through his 
Death Pulse. Additionally, Necrophos is an ideal 
Mekansm carrier. Should one be bought, kills against Necrophos' team can be difficult to secure due to the damage-over-time nature of Doom and his abilities.
* Doom typically wants to be a hero that soaks attention from the enemy team and takes the role of an initiator and disabler. As such, Doom is an ideal target for 
Reaper's Scythe, as it is likely Doom will be at the fore-front of any fight.
Enchantress
* Enchantress has a very low health pool, allowing Zeus to burst her down quickly before she can heal off the damage with Nature's Attendants.
* Zeus will not be affected by Untouchable, as he won't try to attack her with right clicks anyway.
* Zeus can stay out of her attack range while trying to kill her, especially if he has bought an 
Aether Lens.
* Most heroes would want to get on top of Zeus to kill him, but Enchantress does not have this option as doing so would severely limit her damage from Impetus.
* The exception is the laning phase, where Enchantress can gank Zeus if she Enchants a good creep.
Additional:
* Enchantress has a very low health pool, allowing Zeus to burst her down quickly before she can heal off the damage.
* Zeus will not be affected by Untouchable, as he won't try to attack her with right clicks anyway.
* Zeus can stay out of her attack range while trying to kill her, especially if he has bought an Aether Lens.
* Most heroes would want to get on top of Zeus to kill him, but Enchantress does not have this option as doing so would severely limit her Impetus damage.
* The exception is the laning phase, where Enchantress can gank Zeus if she Enchants a good creep.
Enchantress
* Untouchable won't mitigate Venomancer's magical damage, and Enchantress is vulnerable to magic damage.
* Both 
Venomous Gale and 
Poison Nova lower the amount of healing received by Enchantress and her allies from Nature's Attendants.
Enchantress
* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.
Enchantress
* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.
Enchantress
* Heroes with nukes: 
Bane, 
Lich, 
Lion, 
Skywrath Mage
Doom
* Heroes with a slow attack rate will find themselves struggling to take out Tombstone, like Doom.
Enchantress
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: 
Phantom Assassin, 
Clinkz, 
Sniper, 
Enchantress.
Enchantress
* Heroes with nukes that can jump her: 
Clockwerk, 
Snapfire, 
Spirit Breaker, 
Techies
Enchantress
* Heroes with break can disable Untouchable for a while: Doom and Shadow Demon (via Aghanim's Scepter), Viper, Shadow Shaman with Hex Breaks talent.
Enchantress
* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage
Additional:
* Untouchable is useless versus constant Arcane Bolts, and it doesn't help that her strength gain is the lowest in the game.
* A jungle Enchantress can weaken lanes and make Skywrath Mage's job easier.
* The magic amplification from Ancient Seal makes her even squishier to Skywrath and his allies' magic nukes.
Doom
* Heroes with low mana pools (eg.Doom and
Tidehunter) will feel the effects of Silencer's Intelligence Steal far more than others.
Enchantress
* Heroes that can jump on her: 
Slark, 
Queen of Pain, 
Anti-Mage
Additional:
* Queen of Pain often relies more on abilities than right-clicks, making Untouchable nearly useless against her.
* Enchantress also has a lower health pool than Queen of Pain, making her vulnerable to Queen of Pain's damage burst.
Enchantress
* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage
Additional:
* Enchantress is very fragile without any form of magic resistance, allowing Lion to easily burst her down.
* Nature's Attendants is a slow heal, making not as much effective against Lion's burst as it could be.
* Her raw movement speed is a fair escape/mobility mechanism, which may allow her to avoid a blindly cast 
Earth Spike, but does nothing against the rest of Lion's abilities, since they are single target and can't miss.
* Since Lion's damage comes mostly from his skills, Untouchable does nothing to mitigate it.
Doom
* Heroes who can disable Mars but cannot do any damage to him, meaning he just tanks their abilities: Doom, 
Magnus.
Enchantress
* Heroes with nukes that can jump her: Clockwerk, Snapfire, Spirit Breaker, Techies
Additional:
* Techies does huge amounts of magical damage, which will bypass Untouchable.
* Enchantress depends on abilities to do damage and heal, which Blast Off's silence prevents.
Enchantress
* Heroes with nukes that can jump her: Clockwerk, Snapfire, Spirit Breaker, Techies
Doom
* Heroes who often build Linken's Sphere: Weaver, Morphling, Medusa.
Doom
* Lone Druid is essentially two heroes. Dooming one over the other still leaves Lone Druid or his bear able to do their job during a fight. Additionally, Lone Druid is not hindered as much as other heroes by the silence and mute of Doom since the hero relies more on attacks than abilities.
Additional:
* Doom will be very hestitant to use Doom on the Spirit Bear, and using it on Lone Druid himself will not stop the bear from attacking him especially if True Form has already been used.
* 
Devour does not work on the Spirit Bear and pushes the lane so Lone Druid can safely farm under tower.
Doom
* Besides 
Lone Druid and 
Meepo, Doom is potentially good versus every hero since Doom will render any hero helpless for up to 16 seconds. This is particularly true for fragile heroes that heavily rely on mobility to stay alive.
Enchantress
* Enchant can not control golem 
Chaotic Offering from Warlock.
Doom
* Supports with useful teamfight or contribution spells will be helpless against Doom: 
Dazzle, 
Oracle, 
Warlock.
Additional:
* Doom will not only prevent Warlock from casting his abilities in team fights, but also it reduces the healing from Shadow Word.
* Devour allows Doom to acquire a stun from neutral creeps, allowing him to interrupt Upheaval without having to use Doom.
Doom
* Drow Ranger can be difficult to get on top of, thanks to her 
Frost Arrows and 
Gust. With these two abilities, Drow Ranger is able to effectively 'kite' Doom and minimize his impact during team fights and laning stage.
* Much of Drow Ranger's effectiveness comes from her passive 
Marksmanship, which is not disabled by Doom.
Enchantress
* Range-reliant heroes: Sniper, 
Drow Ranger
Doom
* Due to the nature of the hero, Sniper is typically situated in the back of the fight, potentially making him a difficult target to initiate on and fight.
* Sniper is largely a right-click hero, and as such isn't as an effective of a Doom target as other heroes.
* Thanks to 
Shrapnel and 
Headshot, Sniper is able to effectively 'kite' Doom, preventing him from closing the distance between the two.
Enchantress
* Range-reliant heroes: Sniper, Drow Ranger
Doom
* Phantom Lancer's illusions can make it difficult to Doom the real hero. Should Doom figure out the real hero, the illusions can make it difficult to cast any abilities, as their hitboxes can be used to body-block the real Phantom Lancer.
* Phantom Lancer is an ideal Diffusal Blade carrier. With it, he can quite easily deplete Doom's already poor mana pool, potentially making him unable to cast his abilities to escape, retaliate or heal.
* Doom lacks any effective ability to clear waves of creeps and illusions, as the vast majority of his abilities are single-target. Without an answer, Doom may find it difficult to deal with Phantom Lancer's presence.
Doom
* Doom's Doom marks Phantom Lancer with a highly visible effect, and also silences and mutes him.
* Heroes with undispellable debuffs will help identify the real Phantom Lancer through visual effects or debuff indicators, provided that it was cast on the real Phantom Lancer to begin with:
* Doom's Doom marks Phantom Lancer with a highly visible effect, and also silences and mutes him.
* 
Bloodseeker's 
Rupture shows a clear red trail effect on the real Phantom Lancer.
* 
Ancient Apparition's 
Ice Blast will only debuff Phantom Lancer and not his illusions.
* 
Grimstroke's 
Soulbind is undispellable.
* Shadow Demon's 
Demonic Purge is undispellable.
* 
Monkey King's 
Jingu Mastery is undispellable and puts a big yellow Mark over his head.
Enchantress
* Enchantress can turn Chen's own creeps against him with Enchant. The creeps still keep the health buff Holy Persuasion granted them. 
Aghanim's Shard gives Enchantress 
Little Friends ability, which allows her to turn multiple of Chen's creeps all at once against him.
* Untouchable and Nature's Attendants make her difficult to kill.
Additional:
* Even though Chen can use 
Holy Persuasion on creeps controlled by Enchant, Enchantress can also use Enchant on Chen's creeps, making it somewhat of a double-edged sword type of matchup.
* Aghanim's Shard gives Enchantress Little Friends ability, which she can use to turn all of Chen's creeps against him for a short time when casted on him.
* Impetus's high burst damage can often kill any of Chen's allies before he can save them with 
Hand of God.
Doom
* Doom can easily kill Chen's creeps and obtain their abilities with Devour.
* 
Scorched Earth's area-of-effect can clear multiple of Chen's creeps at once.
* Doom renders Chen completely helpless, and unable to save himself or his allies with Hand of God. Aghanim's Scepter upgraded Doom also allows Doom to cast Doom on himself and disable both, Chen and his creeps around him.
Enchantress
* Untouchable prevents Clinkz from harassing Enchantress in lane by lowering his attack speed.
* Nature's Attendants helps Enchantress to sustain through Clinkz's harassment in lane.
Doom
* Scorched Earth deals damage to Clinkz during Skeleton Walk.
* Doom shuts down Clinkz entirely, as it prevents him from casting any of his spells and contributing a large amount of damage in teamfights.
Enchantress
* Impetus will deal huge amounts of damage when he uses a 
Fire Remnant to escape.
* 
Flame Guard is useless against Impetus as it deals Pure damage.
* Enchant can be used to dispel Flame Guard.
Doom
* Ember Spirit cannot use his 
Activate Fire Remnant to escape while affected by Doom.
Enchantress
* Untouchable makes her heavily reduce Elder Titan's physical damage output on her without Spell Immunity.
* Enchant can purge 
Astral Spirit's buff without Spell immunity.
* Nature's Attendants can protect her if she survives the full combo and manages to juke around.
Doom
* Infernal Blade deals scaling damage and is useful against high HP targets such as Elder Titan. It also can interrupt 
Echo Stomp if quick enough.
* Doom has very low base armor and naturally high HP, so he isn't significantly affected by 
Natural Order.
Enchantress
* Impetus is not blocked by 
Guardian Angel. A {U:Satyr Banisher} can also be controlled to dispel Guardian Angel.
Additional:
* Enchantress's Impetus deals pure damage instead of physical damage and ignores Guardian Angel, thus fully negating one of Omniknight's most important abilities for teamfights.
* Similar to Doom, Enchantress can use Enchant on Satyr Banisher, which will give her access to Satyr Banisher's 
Purge, and allow her to remove Heavenly Grace and Guardian Angel.
Doom
* Doom applies a basic dispel upon cast, so it can remove Guardian Angel.
* Casting Doom on Omniknight will also prevent him from healing allies with 
Purification, or casting buffs like 
Repel and Guardian Angel, basically turning him into a harmless creep.
Additional:
* Doom turns Omniknight into a walking creep, or completely takes out his buffed cores, also removing Heavenly Grace and Guardian Angel in the process.
* With Devour used on Satyr Banisher, Doom will have access to Satyr Banisher's Purge, which will allow him to remove Heavenly Grace and Guardian Angel.
Enchantress
* Untouchable makes it near impossible to stack Burning Spears.
* Impetus' pure damage puts an instant end to Huskar's low-health brinkmanship.
Doom
* Doom with the {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent} talent can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, 
Huskar, 
Underlord.
Enchantress
* Heroes that have an escape that doesn't disjoint projectiles: 
Mirana, 
Faceless Void, Magnus
Doom
* Faceless Void relies on 
Time Walk for mobility and survivability but he can be prevented from utilizing it through Doom.
* Doom has a high cooldown duration for every ability except Infernal Blade, so he is not significantly affected by 
Time Dilation.
Doom
* High health heroes (
Axe, Doom) fall fast with Fury Swipes stacks.
Enchantress
* Enchant can dispel 
Overpower.
* Enchant's slow can help kite Ursa in fights and also in lane.
* Enchantress can out harass Ursa in lane by using her long attack range and Untouchable, as well as out sustaining him with Nature's Attendants.
Doom
* Doom makes Ursa less disruptive, and it cannot be dispelled with Enrage upgraded with Aghanim's Scepter.
Enchantress
* Untouchable negates Inner Beast's attack speed bonus, making her hard to kill even if stunned by Primal Roar.
* Enchantress can also take control of Beastmaster's summons.
Additional:
* Enchant can control Beastmaster's boars with Enchant, mitigating his effectiveness during the laning stage and teamfights.
Enchantress
* Impetus pure damage ignores the extra armor granted from Wukong's Command.
* Enchant can dispel Monkey King's Jingu Mastery bonuses.
* Untouchable makes it hard for Monkey King to land Jingu Mastery stacks.
* 
Sproink allows Enchantress to escape from Wukong's Command.
Enchantress
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of 
Chen or Enchantress.
Enchantress
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, Magnus
Doom
* Doom completely takes Mirana out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Doom
* 
Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With his upgraded level 25 talent, it also breaks Bristleback's passive, rendering him more vulnerable.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing 
Warpath.
* If Doom chooses the Level 25 talent {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent}, he can disable 
Bristleback and Warpath, taking away much of his durability and damage potential in team fights.
Doom
* Doom completely takes Invoker out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on Linken's Sphere.
Doom
* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom can buy 
Radiance or use his Scorched Earth to quickly wipe out a swarm of Treants.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.
Doom
* Doom is generally tanky and has naturally high health, allowing him to survive Puck's onslaught in any stage of the game.
* His namesake ultimate Doom is one of the best solutions to counter Puck, as it will silence Puck for a lengthy duration. A Puck silenced for more than 3 seconds usually ends up dead.
* In addition, if Doom chooses the Level 25 talent Doom applies Mute, Puck will not be able to use items altogether, most especially 
Blink Dagger and 
Eul's Scepter of Divinity, making Doom a nightmare to deal with as Puck.
Doom
* Doom can completely shut down Dazzle through Doom, as it prevents him from casting his abilities and, by extension, gaining Bad Juju stacks.
Doom
* Infernal Blade's damage is calculated by percentage of maximum health. Since Spectre is usually tanky, it will hurt her more than most normal attacks.
* Doom can take out Spectre out of a teamfight completely. When combined with the level 25 talent {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent}, it will disable both 
Desolate and 
Dispersion, taking away her extra damage and durability.
Additional:
* Infernal Blade's damage is calculated by percentage of maximum health, meaning that it will hurt Spectre more than most normal attacks, negating some of her tankiness.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Spectre.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom makes Spectre less disruptive. Combined with Aghanim's Scepter, it will disable Spectre passive skills, reducing her potential in teamfights.
Doom
* Doom prevents Storm Spirit from using all of his abilities and items, rendering Storm Spirit useless in a fight.
Doom
* Doom has several disable abilities to choose from jungle creeps (e.g. 
War Stomp, 
Ensnare) to deal with Shadow Fiend who lacks escape abilities.
* When Doom combines creep abilities with Scorched Earth, Infernal Blade, and Doom, Shadow Fiend most likely will die as he cannot use Shadowraze and Requiem of Souls to protect himself, and also cannot even flee by using 
Shadow Blade or Blink Dagger.
* Although Shadow Fiend has a high physical damage output, Doom has a large health pool to survive it, meaning Doom's combo with high magical damage output will shutdown Shadow Fiend first.
* Doom usually buys Radiance to improve his damage, making his nuke combo more deadly to Shadow Fiend. The blind also prevents Shadow Fiend from landing his attacks often.
Doom
* Infernal Blade deals high damage to Pudge due to his scaling health and strength gain from 
Flesh Heap.
* Using Doom with timing against Pudge who had just activated 
Rot would usually kill him.
Additional:
* Doom disables the toggling of Rot and, if cast at the right time, may leave Pudge with a potentially lethal health drain.
* Doom's naturally high health, strength gain and damage output makes him a poor target for Pudge.
* The damage of Doom's Infernal Blade scales with the target's maximum health, which is particularly effective against Pudge due to his naturally high health and further health granted by stacks of Flesh Heap.
Doom
* Infernal Blade deals scaling damage and is useful against high HP targets such as Tidehunter.
* Doom prevents Tidehunter from casting his 
Gush, 
Anchor Smash and 
Ravage, making him useless in team fights.
* If Doom chooses the Level 25 talent {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent}, he can also disable 
Kraken Shell, reducing his survivability.
Doom
* Doom can stop Death Prophet from casting spells, which makes her useless during team fights if she didn't cast Exorcism before the fight, and also nullifies healing from Exorcism and Spirit Syphon. Furthermore, Doom can use Scorched Earth to chase after her.
Doom
* Doom is effective against every hero, and Void Spirit is no exception. Being unable to cast spells or items during fights for 16 seconds nullifies his impact entirely.
* Doom has a very versatile build and can consume creeps which has abilities that can stun or provide additional magic resistance.
* Doom's high strength gain and versatility in items can be effective against Void Spirit's magical damage.
Doom
* Doom's low armor makes him weak against Alchemist's high physical damage output.
Enchantress
* Untouchable greatly reduces Chemical Rage's attack speed advantage.
Doom
* Doom can disable 
Chemical Rage's increased healing, rendering Alchemist helpless against Doom.
* Attacks from Infernal Blade can deal serious damage to Alchemist as it deals damage based on the hero's maximum health.
Doom
* Doom makes Ogre Magi less disruptive.
* Infernal Blade effectively negates Ogre Magi's durability.
* With Aghanim's Scepter, he can disable Multicast.
Doom
* Doom pierces spell immunity and can prevent Enigma from casting any spells or using items until the duration of the spell depletes, as well as cancelling a 
Black Hole.
* While Doom can be blocked by a Linken's Sphere, which is a common item on Enigma, Aghanim's Scepter upgraded Doom allows Doom to cast Doom on himself to affect enemies near him, and if Doom can combine this with Blink Dagger, he will be able to jump on Enigma while he is channeling Black Hole. Aghanim's Scepter upgraded Doom can also cancel Black Hole if any of Enigma's allies affected by Doom gets too close to him for it's duration, ignoring both, 
Black King Bar and Linken's Sphere.
Doom
* Infernal Blade's damage is calculated by a percentage of maximum health, meaning that it will hurt Axe more than most normal attacks, negating some of his durability.
* Doom can pick up several different abilities from neutral creeps using Devour, some of which can be annoying to Axe.
* Mud Golem, Dark Troll Summoner, Harpy Stormcrafter, Satyr Mindstealer or Satyr Tormenter are good examples.
* Doom's naturally low attack speed makes Counter Helix less likely to proc, and his high base health allows him to take a few Helixes with no danger.
* Doom makes Axe less disruptive, preventing him from using his skills or items. At level 25, there is a branch of the talent tree that makes Doom apply Break, allowing Doom to disable Counter Helix, making Axe effectively useless for a lengthy duration.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Axe.
* Doom has low attack speed because of his high Base-Attack-Time, poor agility gain and limited attack-speed granting items which are commonly built. This means Doom will trigger 
Counter Helix less often and thus is an unideal target for initiation.
* Doom has naturally high HP so it takes longer for Doom to be brought down to the killing threshold of 
Culling Blade.
* Axe is highly reliant on his abilities and items to be effective during a fight. Without the usage of 
Berserker's Call and Blink Dagger due to Doom, Axe offers very little in the way of damage, effectively removing him from a fight.
Doom
* Scorched Earth can be used to engage Visage while removing Gravekeeper's Cloak charges.
* Infernal Blade will deal tremendous amounts of damage over time due to Visage's high health pool.
* Doom completely nullifies Gravekeeper's Cloak and prevents Visage from casting spells.
Doom
* Doom will make Abaddon unable to use Mist Coil, Aphotic Shield, and the active component of Borrowed Time, also upgraded with Aghanim's Scepter can break Curse of Avernus and the passive component of Borrowed Time ,which means his allies could be easily disabled or killed.
Doom
* Weak damage but high tick rate or persist in a long time: Slark, 
Gyrocopter, Queen of Pain, Shadow Shaman (
Shackles), 
Jakiro, 
Pugna, Doom
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, 
Witch Doctor, Lycan, 
Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: 
Phantom Lancer, 
Chaos Knight, 
Naga Siren (bonus for her 
Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna, Doom
Enchantress
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, Magnus
Doom
* Heroes with silences: 
Puck, Doom, 
Riki.
Enchantress
* The burst damage from Timbersaw's abilities is more than enough to deal with Enchantress and her creeps.
* Timbersaw doesn't rely on his physical attacks, which makes Untouchable useless against him.
* 
Timber Chain can close the gap between them and minimize damage from Impetus.
* Bear in mind, however, that Timber Chain can also work against Timbersaw if used to escape and that Impetus can ignore 
Reactive Armor if Enchantress is not a primary target for Timbersaw or if he is disabled.
* Timbersaw is a common wielder of 
Lotus Orb, which will allow him to reflect Enchant back at Enchantress and dispel most debuffs as well.
Enchantress
* Timbersaw has a difficult time against magical and pure damage: 
Lina, 
Leshrac, Enchantress, Queen of Pain
Doom
* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a team fight - both for mobility, damage and crowd control. Timbersaw offers very little, impactful right-click damage, and thus Doom is particularly crippling against him.
* Additionally, when Doom chooses the {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent} talent, Doom disables Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.
Additional:
* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. Also it's useful since Timbersaw has high HP due to the damage scales based on max HP.
Doom
* Heroes with the ability to heal allies will not be able to heal heroes affected by Doom: Chen, Dazzle, 
Io, Oracle, 
Omniknight, Witch Doctor, 
Winter Wyvern, 
Abaddon, etc.
Doom
* Heroes with the ability to heal allies will not be able to heal heroes affected by Doom: Chen, Dazzle, Io, Oracle, Omniknight, Witch Doctor, Winter Wyvern, Abaddon, etc.
Doom
* Doom with the {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent} talent can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, Huskar, Underlord.
Doom
* 
Silencer's 
Global Silence and Doom's Doom makes Earthshaker temporarily useless.
Doom
* Heroes with the ability to heal allies will not be able to heal heroes affected by Doom: Chen, Dazzle, Io, Oracle, Omniknight, Witch Doctor, Winter Wyvern, Abaddon, etc.
Doom
* Single-target disablers will have difficulty locking down a Chaos Knight with Phantasm active: Bane, 
Beastmaster, Bloodseeker, Clockwerk, Doom, Shadow Shaman.
Enchantress
* Untouchable will significantly slow down Chaos Knight's physical damage with Phantasm.
* Impetus deals double damage to illusions, making it effective against Phantasm.
Additional:
* Untouchable makes all of Chaos Knight's attacks slow therefore he is unable to deal damage, especially his critical damage of 
Chaos Strike, also enables Enchantress to escape easily from his attacks.
* However, 
Reality Rift can still pose a danger to Enchantress because Chaos Knight can decrease a good amount of armor, making it dangerous because of her little armor stat, as he can burst down Enchantress easily if any of Chaos Knight's allies can apply a break on Enchantress.
Enchantress
* Heroes like Enchantress and Chen, or heroes that make use of 
Helm of the Dominator are weak to Crystal Maiden, as Frostbite can do wonders against Enchant, Holy Persuasion, or dominated creeps. Careful though, as an army of carefully controlled creeps (Enchantress and Chen) can hold many stuns that will cancel Freezing Field.
Additional:
* 
Frostbite does 1000 magical damage to Enchantress's creeps and roots them for 10 seconds, which hinders her ability to gank.
Doom
* Doom alone can easily pick off Crystal Maiden since she is fairly fragile, even with using only basic attacks, Infernal Blade, and Scorched Earth.
* Doom prevents her from using any abilities in a fight, making her impact negligible.
* Devour allows Doom to acquire a stun, allowing him to cancel Freezing Field without having to use Doom.
Enchantress
* Heroes with haste can negate Enchant's slow: Weaver, Dark Seer, Lycan, Centaur Warrunner.
Enchantress
* Lycan relies heavily on right clicks making Untouchable very effective against him.
* If he tries to run away Impetus will do huge amounts of damage.
Additional:
* She can Enchant one of the wolves to her side.
* Lycan will struggle greatly to harm Enchantress through her Untouchable which can seriously slow down Lycan's attack speed even if Lycan is spell immune.
Enchantress
* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage
Doom
* Doom shuts down Anti-Mage's escape capabilities with Blink. The ability also deals pure damage, which ignores the protection from Counterspell.
* However, a well-timed Counterspell can reflect it back.
* If Doom has Aghanim's Scepter, Doom can break Mana Break and Counterspell, weakening both his offense and defense.
* Doom's low mana pool causes him to take little damage from Mana Void.
Additional:
* Doom prevents Anti-Mage from maneuvering around a fight or escaping from an initiation using 
Blink. Additionally, Doom deals pure damage, which is not affected by 
Counterspell. This can quickly whittle away Anti-Mage's naturally poor health pool.
* However, Doom must be careful when using Doom as a well-timed Counterspell can block and reflect it back against Doom himself.
* The Level 25 talent {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent} will also disable 
Mana Break and Counterspell's passive component, which makes Anti-Mage significantly less effective in fights and more susceptible to the high magical damage of Doom's abilities and his allies.
Enchantress
* Heroes with nukes that can jump her: Clockwerk, Snapfire, Spirit Breaker, Techies
Enchantress
* Spirit Breaker won’t do much harm to Enchantress because of Untouchable and Nature's Attendants. Unless Enchantress is low on HP, Spirit Breaker won’t be able to catch her with mere spells.
Enchantress
* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage
Doom
* Both Infernal Blade and Doom can be used to disable Bane while he is channeling Fiend's Grip.
* A similar effect can be achieved by using Devour on {U:Centaur Conqueror}, which will give him access to War Stomp.
Enchantress
* Enchantress has pitiful HP, even more pitiful than Luna, so 
Lucent Beam and 
Eclipse will often harass and/or kill her through her Untouchable.
* With 
Moon Glaives, Luna can clear Enchantress's creep wave efficiently.
Additional:
* Though Enchantress's Untouchable can greatly reduce Luna's attack speed, and can go through any form of Spell Immunity, she has a pitiful HP so Lucent Beam and Eclipse can kill her very quickly.
* Moon Glaives allows Luna to clear Enchantress's creeps very efficiently.
Enchantress
* Heroes that create illusions: 
Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, 
Terrorblade) or bring other units into the fight (such as 
Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and 
Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Doom
* Heroes that can keep Luna locked down for a long time can be a threat (she is very item and spell dependent): Faceless Void, 
Legion Commander, Doom.
Enchantress
* Meepo can quickly kill Enchantress with a 
Poof combo, rendering Untouchable useless.
Enchantress
* Enchantress's Untouchable slows down Meepos attacks and Impetus can deal heavy pure damage to a single Meepo, however once Meepo has closed the gap she is an easy target for Poof.
Doom
* Besides Lone Druid and Meepo, Doom is potentially good versus every hero since Doom will render any hero helpless for up to 16 seconds. This is particularly true for fragile heroes that heavily rely on mobility to stay alive.
Doom
* Terrorblade can use 
Sunder to save his allies who are Doomed.
Enchantress
* Heroes that can dominate his illusions or create their own illusions of him: Dark Seer, Morphling, Enchantress, Shadow Demon, Grimstroke with Aghanim's Scepter.
Enchantress
* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage
Doom
* Heroes with silencing abilities can be particularly deadly when Slark is trying to escape: Silencer, 
Death Prophet, Puck, Doom.
Enchantress
* 
Vendetta can deal great damage against her. However, it requires an direct attack, so Nyx Assassin may have difficulties applying Vendetta on her.
* Enchantress's lack of mobility makes her a primary target for ganking with Vendetta.
* 
Mind Flare can deal a great damage against her due to being an Intelligence hero.
* 
Spiked Carapace can reflect Impetus and stun Enchantress.
Additional:
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.
Doom
* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and fighting back with Spiked Carapace.
* Doom's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off.
Enchantress
* 
Windrun's speed allows easy pursuit or escape, while the evasion greatly reduces the threat of Enchantress's Impetus, especially when retreating.
* 
Shackleshot is a powerful disable if Enchantress gets too close to one of her own minions.
* 
Focus Fire can negate Untouchable.
Doom
* Doom completely takes Windranger out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Additional:
* Doom completely takes Windranger out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Doom
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, 
Troll Warlord.
Doom
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, 
Night Stalker, Drow Ranger, Doom .
Doom
* 
Feast deals damage and heals Lifestealer based on the target's maximum HP, which is greatly effective against naturally high HP heroes such as Doom.
* 
Rage allows Lifestealer to become spell immune to negate the magical damage of Infernal Blade and Scorched Earth.
* Doom has no effective means of escape from 
Open Wounds and 
Ghoul Frenzy. This is particularly devastating in the laning stage, where Doom may have to play a much more passive, conservative play style as a result.
Enchantress
* Since Untouchable pierces Spell Immunity, Lifestealer cannot burst her down even with Rage; meaning she can heal herself back to full HP.
Doom
* Doom generally does not impede Sven in almost any way, provided he has activated God's Strength beforehand.
Enchantress
* Against her Untouchable, Sven is barely able to hit Enchantress even with his Black King Bar.
Doom
* Heroes without blink mechanisms or spell immunity will have a hard time positioning against 
Pit of Malice: 
Sven, 
Tiny, 
Wraith King, 
Dragon Knight, Meepo, Doom, 
Bounty Hunter, Dark Seer, 
Undying, 
Alchemist, Legion Commander.
Doom
* Doom with the {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent} talent can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, Enchantress, Huskar, Underlord.
Additional:
* Infernal Blade does damage based on percentage health, and is useful against high health pool hero like Underlord.
* Doom can prevent Underlord from spamming his abilities and most important is to prevent him from using Fiend's Gate to escape.
Enchantress
* Magnetic Field makes Impetus miss; if Enchantress decides to enter the field, she is giving up bonus damage since Impetus deals greater damage at higher distance away from targets.
Doom
* Arc Warden relies on items and abilities, as well as his 
Tempest Double, to deal damage to enemies. Doom effectively denies that and makes Arc Warden useless in fights.
Enchantress
* Heroes with little health or magic resistance are easily picked off with Oracle's magic burst, such as Skywrath Mage, 
Crystal Maiden, or Enchantress.
Doom
* Heroes with the ability to heal allies will not be able to heal heroes affected by Doom: Chen, Dazzle, Io, Oracle, Omniknight, Witch Doctor, Winter Wyvern, Abaddon, etc.
Enchantress
* All of Tinker's damage is magic/pure and completely ignores Enchantress's Untouchable. And Tinker's nukes can quickly decimate her small HP pool, sometimes even preventing Enchantress from even responding.
* As Enchantress relies solely on her primary attacks to deal damage, and rarely builds something to dispel it, Laser's Blind is particularly effective.
* However, Enchantress will probably build a Linken's Sphere against Tinker's Laser, so getting an additional disable is highly recommended.
Doom
* Tinker is heavily dependent on his abilities and Doom prevents him from using any of them.
* This becomes even worse if Doom chooses the level 25 talent {ValueColor:1|Doom applies Mute|25tal} {Symbol:Talent}, which will prevent Tinker from using items such as Blink Dagger.
Additional:
* Tinker is heavily reliant on casting his spells and Doom can disable all of his abilities and items. An Aghanim's Scepter only makes it harder for Tinker to survive.
Enchantress
* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.
Doom
* Doom does not disable
Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target. 
Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.
* Medusa is an ideal