* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

* Magnus has very mediocre damage against Alchemist, because he can survive the stun duration of Reverse Polarity with Chemical Rage.

* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.

* Chemical Rage mitigates damage from Burning Spear.
Additional:
* Chemical Rage negates almost all damage from Burning Spears.

* Time Dilation prevents Bristleback from spamming his low-cooldown abilities, greatly reducing his damage and effectiveness.
* Chronosphere allows allies to reposition and hit Bristleback from the front, bypassing his defensive bonus from behind.
* Bristleback has no way to prevent Void from using Time Walk.
Additional:
* Time Dilation while Quill Spray and Viscous Nasal Goo are on cooldown will make these abilities unusable for a long time, rendering Bristleback nearly useless.
* Bristleback cannot turn inside the Chronosphere, which makes it easy to attack him from the front, completely bypassing his passive damage reduction.

* Time Dilation affects Morphling's low cooldown spells, making them unusable for a long time, rendering Morphling nearly useless.
* Morphling cannot use Attribute Shift while he is inside Chronosphere which makes it easy to kill him.

* Time Dilation while Spear of Mars and God's Rebuke are on cooldown will make these abilities unusable for a long time, rendering Mars nearly useless.
* Mars cannot turn inside the Chronosphere, which makes it easy to attack him from the back, bypassing Bulwark completely.
Additional:
* Time Walk allows Faceless Void to escape or enter Arena Of Blood, and helps him recover from Mars' burst damage.
* Time Lock's magical damage ignores Bulwark.
* Chronosphere allows Faceless Void to reposition behind Mars, ignoring his Bulwark while he is helplessly frozen in time.

* Time Dilation is similar to a long duration silence, making Timbersaw useless in team fights, or forcing him to adapt his build.
* Time Walk negates Timbersaw's burst damage.
* Time Lock provides magical damage and lock down, and is effective against both Reactive Armor and Timber Chain.
* In conjunction with Time Lock's magical damage, Chronosphere can destroy Timbersaw before he has time to react, and creates a large obstacle that obstruct's Timber Chain's mobility.

* Time Dilation affects Queen of Pain's low cooldown abilities, making them unusable for a long time, rendering Queen of Pain nearly useless.
* Chronosphere provides excellent lockdown against Queen of Pain, allowing for reliable kills in all stages of the game.
Additional:
* Time Walk and Backtrack allows Faceless Void to easily negate Queen of Pain's burst damage.
* Chronosphere prevents Queen of Pain from escaping with Blink, and her low survivability makes her an easy kill.
* Time Dilation will prevent Queen of Pain from using her low-cooldown spells or force her to buy Black King Bar or a Eul's Scepter of Divinity to dispel the debuff and re-engage.

* Time Dilation, while Spell Steal with Aghanim's Scepter is on cooldown will make it unusable for a long time, reducing Rubick's potential.
* Rubick's own Chronosphere stolen with Spell Steal cannot stun Faceless Void.

* Beware of placing the Death Ward if Chronosphere is off cooldown, as it will cancel the effect and leave Witch Doctor vulnerable if he does not react in time.

* Time Dilation while Static Remnant and Electric Vortex are on cooldown will make these abilities unusable for a long time, reducing Storm Spirit's potential.
* Faceless Void can catch Storm Spirit during Ball Lightning with a well-timed Chronosphere or Time Walk.

* Time Dilation can limit Zeus to casting his abilities only once in a fight, effectively serving as a 6/8/10/12 second silence.
* Time Walk negates Zeus's burst damage.
* Chronosphere makes Zeus the best target for Void because of his low mobility.

* Time Walk makes it impossible for Primal Beast to stay on top of Faceless Void with his abilities and allows him to heal burst damage dealt to him.
* Once Faceless Void has an Aghanim's Shard, Onslaught can be easily escaped. He could also choose to get a lower cooldown on Time Walk, making it even harder for Primal Beast to catch him in fights or stop his initiations.
* Time Dilation will make Primal Beast useless for an extended time after casting his abilities if he does not have a dispel.
* Chronosphere has many uses such as stopping Primal Beast from casting abilities on him or allies or even on a teammate, since Primal Beast has no way to assist allies trapped within the sphere.

* Blade Fury will not protect Juggernaut against Chronosphere or Time Lock.
* Faceless Void can Time Walk out of the range of Omnislash at all points of the game and with ease.

* Time Walk will easily backtrack Lina's burst damage (especially Laguna Blade) if not timed correctly.
* During Chronosphere, squishy heroes like Lina will be main target of Faceless Void in his ultimate.

* Time Dilation while Shukuchi and Geminate Attack are on cooldown will make these abilities unusable for a long time, reducing Weaver's escape potential.
* Chronosphere will reveal Weaver during Shukuchi.
Additional:
* The wide range of Chronosphere makes it difficult for Weaver to avoid it with Shukuchi and, once caught, his low survivability makes him an easy kill.
* With no significant source of burst damage, it is easy for Void to survive combat with Weaver using Time Walk.
* Time Dilation will prevent Weaver from using Shukuchi or force him to use Time Lapse to dispel the debuff and re-engage.

* Time Walk makes it hard for Gyrocopter to pin down Faceless Void. With Backtrack it also negates most of his attacks.
* Time Dilation will prevent Gyrocopter from using his cooldown spells.

* Time Walk could be used to close the distance within Drow Ranger, hindering her Marksmanship bonus.
* Faceless Void could lock down Drow Ranger with Chronosphere before she has the chance to retaliate due to her low health pool.

* Alchemist's Acid Spray can heavily damage Chen's creeps and disrupt his jungling.
* Alchemist builds items like Radiance and Battle Fury, allowing him to quickly clear Chen's creeps.
* Alchemist's Greevil's Greed will grant him more bonus gold as he kills Chen's creeps.

* Chemical Rage will take down Tombstone in no time.
Additional:
* With Greevil's Greed, Alchemist can farm Tombstone zombies and gain a significant gold advantage.

* Alchemist can easily farm Spiderlings with Acid Spray and Greevil's Greed.
* Alchemist's Chemical Rage nullifies Broodmother's Insatiable Hunger
Additional:
* Greevil's Greed makes Broodmother’s spiderlings far more valuable to Alchemist making it important that he does farm them as opposed to other heroes where the spider's bounties are negligible.
* Acid Spray makes it difficult to attack Alchemist in lane without losing some spiderlings to the damage over time, potentially giving him farm he wouldn't have otherwise.

* Frail heroes who lack mobility can also be an easy target to lock down with Chronosphere, such as Drow Ranger, Luna, Sniper, Terrorblade.

* Heroes that can reliably kite out Dispose, Unleash and dodge Rebound, like Ember Spirit, Void Spirit, Storm Spirit, Anti-Mage, Faceless Void, Puck or always build items like Blink Dagger and Force Staff.

* He can quickly take out heroes with low armor (Tiny) with his great physical damage.

* In general, heroes with AoE or long range disables (such as Faceless Void with Chronosphere, Pudge with Meat Hook and Elder Titan with Echo Stomp) hinder Crystal Maiden, preventing her from using Freezing Field to help her team in a fight.

* Clockwerk lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Clockwerk finishes his initiation. Additionally, Clockwerk hates buying Dagon and Ethereal Blade, which are the only itmes that can help him deal with heroes who can recover themselves and turn the fight around to their advantage: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* Enigma lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Enigma finishes his initiation: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Heroes that require burst damage to kill will be difficult for Phantom Lancer to take down: Timbersaw, Axe, Bristleback, Alchemist and Underlord

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Lion, Silencer, Shadow Shaman, Grimstroke, Witch Doctor, Riki, Faceless Void, Skywrath Mage, Puck.

Additional:
* Chronosphere provides excellent lockdown against Anti-Mage, allowing for reliable kills in all stages of the game.
* Time Dilation while Blink and Counterspell are on cooldown will make these abilities unusable for a long time, shutting down his mobility and defensiveness.
* Faceless Void's low mana pool makes him a poor target for Mana Void, although he is very vulnerable should Anti-Mage burn all of his mana.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Faceless Void can lock Lycan down with his Chronosphere pinning him down as long as his ultimate is up.

* Acid Spray and Greevil's Greed will quickly destroy pushes with treants.
* Because of his poor movement speed,Alchemist can catch up and kill him with Chemical Rage.

* Chronosphere's large obstacle denies Pangolier the room to roll around during teamfights, as well as wasting his ultimate's duration.

* Puck cannot use spells if affected by Time Dilation, especially Phase Shift for main survivability as it effectively triples its cooldown.
* Chronosphere can end Puck's life quickly, as stun, more than 3 seconds will be a death sentence to Puck.
* If not silenced, Faceless Void can just Time Walk to undo Puck's Burst damage.
Additional:
* Hard lockdowns such as Chronosphere can end a Puck's life quickly. A Puck stunned for longer than 3 seconds usually ends up dead.
* As the type of hero that spams spells, Time Dilation counters Puck very effectively. Phase Shift is Puck's main ability for survivability, and Time Dilation effectively triples its cooldown.
* If not silenced, Time Walk can easily undo the damage dealt by Illusory Orb, Dream Coil and Dagon.

* Time Walk negates Rupture's damage.
* Chronosphere prevents Bloodseeker from running down and picking off weak enemies during teamfights.
Additional:
* Time Walk will not make Rupture deal damage for the distance jumped and can be used to quickly escape from Blood Rite.

* Time Walk and Backtrack allow Faceless Void to easily negate Oracle's burst damage.
* Time Dilation is effective against Oracle's low-cooldown spells. Although dispellable with Fortune's End, it can still catch Oracle off guard if Fortune's End is on cooldown.

* Frail heroes who lack mobility can also be an easy target to lock down with Chronosphere, such as Drow Ranger, Luna, Sniper, Terrorblade.

* The health regeneration and bonus movespeed from Chemical Rage allows Alchemist to survive through Doom very easily.
* Doom's low armor makes him weak against Alchemist's high physical damage output.
Additional:
* Chemical Rage out-heals Doom to a large degree throughout all stages of the game. Should Alchemist be chemically enraged before being Doomed, Alchemist can become a difficult target to effectively lockdown and kill, thanks to the health regeneration and movement speed bonuses granted by his ultimate.
* Alchemist is an ineffective target for Doom. Alchemist isn't totally reliant on his skills to be effective during a teamfight, due to the right-click nature of the hero.

* Time Walk can easily avoid Invoker's combo damage if doesn't have disables.
* Chronosphere will reveal Invoker during Ghost Walk.
* All of Invoker's hidden cooldowns are affected by Time Dilation, so Faceless Void can easily slow him down a lot.
Additional:
* Time Dilation prevents Invoker from further invoking for the entire duration of the debuff, as well as massively slowing Invoker based on the large amount of spells he has.
* Time Walk will completely negate Invoker's combo damage.
* If Invoker is caught in Chronosphere, he will most likely be the primary target due to the large teamfight contribution he can provide.

* Faceless Void is one of the best heroes against Ember Spirit, providing a lot of ways of dealing with him. Ember Spirit becomes a lot weaker if affected by Time Dilation, as he can no longer spam Sleight of Fist.
* Chronosphere is also a reliable lockdown for Ember Spirit, although it can be evaded sometimes by Activate Fire Remnant. Additionally, Void can easily negate Sleight of Fist damage with Time Walk.
* And finally, Void is a great Diffusal Blade carrier. Not only Manabreak's physical damage not negated by Flame Guard, but it also burns Ember Spirit's mana. That, in turn, prevents him from escaping if he survived Chronosphere.

* Chronosphere provides excellent lockdown against Rage.
* Faceless Void's Time Lock stops Lifestealer from getting health regeneration from auto-attacks

* Time Dilation while Death Pulse and Reaper's Scythe are on cooldown will make these abilities unusable for a long time, rendering Necrophos nearly useless.
* Necrophos cannot use Ghost Shroud while he is inside Chronosphere which makes it easy to kill him.

* Chemical Rage kills Phoenix very quickly in Supernova.

* Time Walk can easily avoid Dawnbreaker's abilities or to escape her gank attempts and backtrack any damage she deals.
* Time Dilation can prevent Dawnbreaker from using her abilities after initiating, and slowing her down severely.
* Time Lock combined with his high attack speed can lock Dawnbreaker in place, preventing her escape with Celestial Hammer.
* Chronosphere locks down Dawnbreaker in place right after she uses Solar Guardian.
* On the other hand, if Solar Guardian is cast beforehand from afar, it may discourage Faceless Void from casting Chronosphere in its location

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.