Huskar
* 
Blade Fury makes Juggernaut immune to the damage from Life Break and Burning Spears.
* It can be instantly activated the second Juggernaut sees Huskar flying towards him with Life Break, blocking all damage.
* 
Healing Ward effectively negates any damage-over-time from Burning Spears.
* Huskar has no defense against 
Omnislash and takes heavy damage due to his low armor.
Nyx Assassin
* Blade Fury makes Juggernaut immune to all Nyx's abilities, except 
Vendetta.
* Omnislash. and 
Swiftslash can burst Nyx down, ignoring 
Spiked Carapace. However, Vendetta can be used to escape, canceling Omnislash/Swiftslash.
Additional:
* Juggernaut's entire skillset greatly counters Nyx Assassin's Spiked Carapace, his most important ability.
* Blade Fury allows Juggernaut to freely attack Nyx Assassin, and deal heavy damage to Nyx Assassin. Nyx Assassin cannot counter Blade Fury with Spiked Carapace because Blade Fury gives Juggernaut spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Juggernaut while he is spell immune.
* Healing Ward allows Juggernaut to recover himself and his allies from Nyx Assassin's damage output.
* Omnislash and Swiftslash from 
Aghanim's Scepter can quickly finish off Nyx Assassin. And just like Blade Fury, Nyx Assassin cannot counter neither Omnislash and Swiftslash from Aghanim's Scepter with Spiked Carapace because both abilities render Juggernaut invulnerable. And if Nyx Assassin has no Vendetta available to use for escaping, both abilities will kill him very quickly before he can do anything.
* Overall, any attempt for Nyx Assassin to gank and kill Juggernaut will hurt Nyx Assassin more than Juggernaut.
Huskar
* 
Corrosive Haze and 
Bash of the Deep will make short work of Huskar's low armor, even if Slardar is alone.
Nyx Assassin
* Corrosive Haze hinders Nyx Assassin's ganking attempts with Vendetta, as well as reducing his armor and make him very vulnerable due to his low health pool.
* 
Guardian Sprint allows Slardar to catch up with Nyx Asssassin and finish him off if he has vision over him.
Huskar
* Huskar is often played at low health to maximize the bonuses from 
Berserker's Blood, and also because his abilities cost health to use. This makes him especially vulnerable to Culling Blade.
* Berserker's Blood gives Huskar no protection against the pure damage of Culling Blade. Its attack speed bonus also means that Counter Helix will proc more often.
* Axe's tankiness and base health regeneration makes it hard for Huskar to take him down with 
Burning Spears.
Additional:
* 
Berserker's Call and 
Blade Mail can be used immediately after Huskar jumps on Axe with Life Break.
* Huskar's high attack speed procs 
Counter Helix repeatedly.
* Huskar's health loss from using his abilities make him a frequent target for 
Culling Blade.
Nyx Assassin
* A well-timed Berserker's Call can expose Nyx Assassin while he is invisible with Vendetta, and prevent him from using Spiked Carapace.
* Axe can use 
Battle Hunger's damage over time to minimialize effects of Spiked Carapace.
* Axe's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off. Especially since Axe is a common 
Heart of Tarrasque wielder, which can completely eliminate any chance for Nyx Assassin to kill Axe alone.
* Culling Blade can often kill Nyx Assassin as he is very fragile and vulnerable to damage while Spiked Carapace is on cooldown.
Additional:
* A well-timed Berserker's Call can expose Nyx Assassin while he is invisible with Vendetta, and prevent him from using Spiked Carapace.
* Axe can use Battle Hunger's damage over time to minimialize effects of Spiked Carapace.
* Axe's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off. Especially since Axe is a common Heart of Tarrasque wielder, which can completely eliminate any chance for Nyx Assassin to kill Axe alone.
* Culling Blade can often kill Nyx Assassin as he is very fragile and vulnerable to damage while Spiked Carapace is on cooldown.
Huskar
* His 
Poison Attack is very useful against Huskar, since he tends to stay at low health.
* 
Nethertoxin disables passive skills like Berserker's Blood.
* It is dangerous for Huskar to jump on Viper because 
Corrosive Skin and 
Viper Strike with the slowdown of movement and attack speed which usually will be deadly for Huskar.
Additional:
* Viper Strike can disable Berserker's Blood, which Huskar relies upon for attack speed and healing.
* The damage from Burning Spear and 
Life Break is largely absorbed by Corrosive Skin. It also will return some damage, making it risky to use Burning Spears in the laning stage.
* Because Huskar wants to be on low health for Berserker's Blood, he is particularly vulnerable to Poison Attack.
Nyx Assassin
* Corrosive Skin minimizes the damage from 
Impale and 
Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from Poison Attack, Nethertoxin, Corrosive Skin and Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common 
Silver Edge wielder to counter this problem at all.
Additional:
* Corrosive Skin minimizes the damage from Impale and Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from Poison Attack, Nethertoxin, Corrosive Skin and Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common Silver Edge wielder to counter this problem at all.
Huskar
* Brewmaster can use Cyclone to disable Huskar's healer for much longer than most other heroes can, to make Huskar vulnerable.
* Huskar has no way to stop Brewmaster from using Primal Split by himself, but can cut a good amount of his high health away if Huskar's team wants to burst Brewmaster down during a different disable.
Nyx Assassin
* 
Cyclone from Storm in 
Primal Split can waste Nyx's Spiked Carapace, since its duration is shorter than the Cyclone's.
Huskar
* Carries that can out damage Huskar will do well against him: 
Legion Commander, 
Faceless Void, 
Troll Warlord, 
Phantom Assassin.
Additional:
* Life Break is almost suicidal when used on Legion Commander, as it invites an instant Duel and Legion Commander herself is a natural Blade Mail carrier.
* Huskar's low survivability and mostly on low health make him particularly vulnerable to Legion Commander's high physical damage.
Nyx Assassin
* Duel's long duration prevents Nyx Assassin escaping from Vendetta. With Aghanim's Scepter, she can also bypass Spiked Carapace.
Huskar
* Huskar is often at low health, providing large Thirst bonuses.
* Life Break triggers Rupture's damage.
Additional:
* Huskar is often at low health, providing large 
Thirst bonuses to Bloodseeker.
* Life Break can trigger 
Rupture's damage.
* A self applied 
Bloodrage together with Blademail means it's almost suicidal for Huskar to jump on Bloodseeker with Life Break
Nyx Assassin
* Heroes with invisibility will be detected by Thirst when they have low enough health: 
Bounty Hunter, 
Templar Assassin, 
Riki, 
Clinkz, 
Weaver, 
Treant Protector, 
Nyx Assassin.
Additional:
* While Burrowing, Nyx is an easy target for a 
Blood Rite, and his only way to counter it is a well-timed Spiked Carapace.
* Thirst is always a threat to Nyx Assassin, hindering his attempt of escape using Vendetta and rendering him unable to surprise Bloodseeker's allies.
* Rupture also prevents Nyx Assassin from escaping with Vendetta, as it forces him to stay still.
Huskar
* 
Doom with the {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent} talent can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, 
Enchantress, 
Huskar, 
Underlord.
Nyx Assassin
* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and fighting back with Spiked Carapace.
* Doom's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off.
Huskar
* Heroes with low armor and little mobility, like Huskar, 
Io, etc. will also have an unfortunate fate.
Nyx Assassin
* Lycan's high health allows him to easily shrug off Nyx Assassin's burst damage and fend him off.
* As Lycan commonly buys 
Black King Bar, he can use it to freely attack Nyx Assassin and chase after him with 
Shapeshift.
* Lycan can also use his wolves from 
Summon Wolves to attack Nyx Assassin while he has Spiked Carapace active without getting stunned himself.
Huskar
* 
Mirror Image can cause Huskar to Life Break the wrong target.
* 
Rip Tide reduces Huskar's already low armor.
* 
Song of the Siren allows teams to recover from Huskar's initiation, as well as the damage over time from Burning Spears.
Nyx Assassin
* Nyx Assassin's skillset is mostly single-targeted, therefore he will have difficulties against heroes with illusions and summons: 
Naga Siren, 
Broodmother, 
Lycan, 
Visage, 
Phantom Lancer. And to make things worse, Nyx Asassin is not a common 
Battle Fury, 
Maelstrom, 
Mjollnir, 
Gleipnir or 
Radiance wielder to counter this problem.
Huskar
* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.
Nyx Assassin
* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, 
Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Huskar
* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.
Additional:
* Whirling Axes (Melee) provides a 60% miss chance, resulting in Huskar's attacks missing a lot of the time if it isn't dispelled.
* Troll Warlord's Fervor ramps up in a very similar way as Huskar's Berserker's Blood: as soon as Huskar has high enough health regeneration, Troll Warlord has a high enough attack speed to negate it.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: 
Axe, Broodmother, 
Dawnbreaker, 
Enigma, Huskar, 
Jakiro, Legion Commander, 
Lina, 
Luna, Lycan, 
Slardar, 
Slark, Troll Warlord, 
Witch Doctor.
Huskar
* Heroes with illusions can overwhelm Huskar: Phantom Lancer, 
Anti-Mage, 
Arc Warden, 
Chaos Knight.
Nyx Assassin
* Nyx Assassin's skillset is mostly single-targeted, therefore he will have difficulties against heroes with illusions and summons: Naga Siren, Broodmother, Lycan, Visage, Phantom Lancer. And to make things worse, Nyx Asassin is not a common Battle Fury, Maelstrom, Mjollnir, Gleipnir or Radiance wielder to counter this problem.
Huskar
* Heroes that deal damage over time will also fail to bring down Abaddon and his allies, such as Huskar, 
Venomancer, or 
Phoenix.
Additional:
* Huskar's damage over time gives Abaddon the opportunity to shield and heal his allies.
* 
Borrowed Time also makes Abaddon a hard support to gank, thus negating Huskar's early game dominance.
Nyx Assassin
* Impale and Spiked Carapace stun can be instantly dispelled by Aphotic Shield.
* Abaddon can use Borrowed Time and easily heal for the duration of Borrowed Time by Nyx's burst damage.
Nyx Assassin
* Nyx Assassin might not kill Abaddon with his nuke, but a support Abaddon will struggle to protect an ally from him.
Huskar
* Jumping on Ursa with Life Break is often suicide for Huskar, as he will be immediately bursted down with 
Fury Swipes.
Additional:
* Huskar likes fights with a long duration and is usually at low health, making him vulnerable against Ursa's physical damage.
* Jumping in with Life Break against Ursa is suicide, as Enrage, Overpower, and Fury Swipes will easily shred Huskar.
Huskar
* Chemical Rage mitigates damage from Burning Spear.
Additional:
* 
Chemical Rage negates almost all damage from Burning Spears.
Huskar
* Huskar's Berserker's Blood provides no protection against Clinkz's physical damage output.
* Huskar has no way to disrupt Clinkz's attacks and no way to kill Clinkz alone, as Clinkz can easily go invisible, teleport away, or even fight back.
* Clinkz will often build the items that counter Huskar and the items he usually builds. These include Black King Bar or 
Monkey King Bar for 
Heaven's Halberd, or a disable item like 
Scythe of Vyse or 
Bloodthorn to prevent him from using 
Inner Fire to disarm.
Huskar
* Shadow Demon's 
Shadow Poison can quickly stack to the point where Huskars generally low health is easily finished off.
* Shadow Demon's 
Disruption can turn Huskar's high attack speed and regeneration against him, It also makes him an easy target for Shadow Poison,
* Shadow Demon commonly builds a 
Meteor Hammer, allowing him to land a heavy stun on Huskar
* Shadow Demon's upgraded 
Demonic Purge breaks Huskar, It also pierces Spell Immunity, Without his passive for 7 seconds Huskar quickly falls in battle
* However note that Shadow Demon is a squishy target and you can often overwhelm him if he is alone, But he can still Disrupt you to escape
Additional:
* Shadow Poison can quickly stack up on Huskar, And with his naturally low health you don't need as many stacks to be effective.
* Disruption turns Huskars high attack speed against him, They also have the highest survivability as illusions due to his passive Berserker's Blood, It also allows you to put Shadow Poison stacks on him,
* Dissimulate turns Huskar's burning damage against his team, You can cast it on an ally who is taking a bunch of Burning Spear stacks and cause Huskar to take high amounts of damage as well
* Scepter upgraded Demonic Purge is your most effective weapon against him, It's 7 second Break causes him to quickly die in battle
Huskar
* Huskar's low armor and movement speed make an easy target for Chaos Knight to initiate on with 
Reality Rift and 
Chaos Bolt.
* Other than Inner Fire, Huskar has no reliable area of effect ability to clear Phantasm illusions.
* Huskar likes to stay at low health to benefit from his Berserker's Blood, thus making him vulnerable to Chaos Knight's high burst physical damage.
Additional:
* Chaos Bolt can stun Huskar when he jump in with Life break, giving 4 seconds maximum for Chaos Knight to deliver a beatdown.
* Reality Rift further reduces Huskar's low armor, boosting Chaos Knight's damage even more.
* Berserker's Blood offer no protection against 
Chaos Strike, which deal physical damage.
* 
Phantasm can be used to dispel the disarm from Inner Fire.
* Although Huskar can use this to disarm the illusion instead, buying himself some times.
Nyx Assassin
* Centaur's low Intelligence makes Mind Flare do low damage.
* With some creative skill builds, Centaur's Hoof Stomp stun duration should always last longer than Spiked Carapace stun, so escaping unscathed is hard for Nyx.
* With 
Blink Dagger and detection, Centaur can devastate Nyx in the open.
* However, bear in mind that Nyx can also easily initiate on Centaur Warrunner as well if he uses Spiked Carapace in anticipation, and with Vendetta. The damage from Retaliate will be reflected back to Centaur Warrunner, stunning him with no chance to react after he's revealed himself, and should guarantee a successful Impale.
Nyx Assassin
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* 
Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy 
Eye of Skadi and 
Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid 
Eclipse, smart Luna will always buy 
Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Additional:
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Huskar
* The damage from Burning Spear can be reduced by turning away from Huskar.
* Bristleback can bait Huskar into using Life Break on him, then turn around and receive very little damage.
Additional:
* Bristleback's tankiness and 
Bristleback allow him to outlast Burning Spears' damage-over-time at almost any point in the game. In addition, if Huskar chooses to cast Life Break on Bristleback, Bristleback can simply turn around before it hits and receive little damage.
* 
Viscous Nasal Goo will reduce Huskar's low armor even further, and 
Quill Spray and 
Warpath will tear him down extremely quickly.
Huskar
* Heroes who rely on magical damage resistance may have a hard time laning against Dazzle as all of Dazzle's abilities deal physical damage instead of magical: Anti-Mage, Huskar, 
Viper.
Nyx Assassin
* Heroes that have a weak laning stage: 
Spectre, Nyx Assassin, 
Clockwerk, 
Spirit Breaker, 
Omniknight, 
Pudge.
Nyx Assassin
* With Aghanim's Scepter, Broodmother will gain access to 
Spinner's Snare, which will allow her to create invisible lines on her webs from 
Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, 
Tusk, 
Ursa, 
Nature's Prophet, Enigma, 
Void Spirit, 
Magnus etc.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, 
Ember Spirit, 
Dark Seer, 
Sand King, 
Doom, Dawnbreaker. However, this also means they are easily stunned.
Huskar
* Heroes with illusions can overwhelm Huskar: Phantom Lancer, Anti-Mage, Arc Warden, Chaos Knight.
Nyx Assassin
* Heroes who build mana boosting items but have low mana regeneration are especially vulnerable against Mana Break and Mana Void: 
Timbersaw, Slark, 
Shadow Fiend, Clinkz, 
Bristleback Nyx Assassin, Magnus
Huskar
* Huskar does not need any mana to fight Anti-Mage as most of his skills cost HP instead. He is a good counter to take away Anti-mage's farm in early to mid-game. He, however, struggles to kill Anti-Mage in the late game.
Additional:
* Huskar is not very reliant on mana to cast his spells, therefore, 
Mana Break is not very effective against him.
* Huskar also has low mana pool, he will take less damage once his mana pool is completely depleted. 
Mana Void is also ineffective against him.
* Huskar comes online earlier than Anti-Mage, and can take over the game before Anti-Mage can farm up.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Huskar
* Heroes with high magical burst can easily kill Huskar when he is at low health: 
Lion, Lina, 
Skywrath Mage
Huskar
* Heroes with illusions can overwhelm Huskar: Phantom Lancer, Anti-Mage, Arc Warden, Chaos Knight.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Nyx Assassin
* Some abilities deals damage from an independent source and not from the hero itself, so Nyx cannot counter them with Spiked Carapace: illusions or summoning units, 
Homing Missile, 
Nimbus, 
Mass Serpent Ward, 
Death Ward and especially 
Techies's mines.
Huskar
* Lina interrupts Huskar on the center line because of her attack range, she can constantly be at a long distance, punching Huskar with her hand, while Huskar needs a very close distance to use Burning Spear
Additional:
* Lina can interrupt Huskar on the center line because of her attack range, she can constantly be at a long distance, punching Huskar with her hand, while Huskar needs a very close distance to use Burning Spear.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Nyx Assassin
* Mind Flare does tons of damage against Lina because of her high intelligence.
* Vendetta can deal heavy damage to Lina while also burning her mana, preventing Lina from casting her abilities.
* Spiked Carapace can easily be used to counter Lina's abilities because of their long cast animation, and could probably kill Lina outright if Laguna Blade is reflected. However, Lina can counter this with 
Eul's Scepter of Divinity, a common item on Lina.
Huskar
* Ice Blast prevents Huskar from healing with Berserker's Blood and negates any lifesteal, making him significantly weaker in battle.
* Burning Spear and Life Break cost Huskar his own health, killing him under the effects from Ice Blast.
* Huskar often builds 
Armlet of Mordiggian which can be deadly during Ice Blast.
Additional:
* 
Ice Blast prevents Huskar from healing, regeneration, health gained from activating an Armlet of Mordiggian and will kill him when his health dips below a threshold. This makes it very dangerous for him to use his abilities.
Nyx Assassin
* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: 
Invoker, 
Silencer, Nyx Assassin, Skywrath Mage, 
Shadow Shaman, Lion and etc.
Nyx Assassin
* Even though Visage's Familiars from 
Summon Familiars are fragile and can be killed quickly with Nyx Assassin's high burst damage, they can deal many instances of damage quickly, minimizing the effectiveness of Spiked Carapace.
* 
Gravekeeper's Cloak and tanky item builds make Visage hard for Nyx to kill with his burst damage. 
Aghanim's Shard upgraded Gravekeeper's Cloak also allows Visage to use 
Stone Form to both recover himself and stun Nyx Assassin if he is close enough to Visage.
* Visage's long range on 
Soul Assumption and 
Grave Chill make him hard to escape from, and Soul Assumption's low cooldown outmatches Spiked Carapace.
Huskar
* Heroes with damage over time abilities can quickly eat through Gravekeeper's Cloak charges like Huskar, Jakiro and 
Queen of Pain.
Huskar
* Mass Serpent Ward rips apart Huskar quickly due to his poor armor.
* As soon as Huskar jumps in, he will be vulnerable to Shadow Shaman's disables if he does not have Black King Bar.
Nyx Assassin
* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill Shadow Shaman, Nyx being particularly deadly. Shadow Shaman must watch out for Slark carefully, as he can break either (but not both unless he makes a mistake) of Shadow Shaman's disables, with 
Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn Shadow Shaman from prey to predator.
Nyx Assassin
* Dragon Knight's heavy armor negates Vendetta's burst physical damage. His large HP pool also gives him a good chance of surviving Nyx Assassin's follow-up nuke damage.
Huskar
* Huskar can burn down Dragon Knight's health quickly during the early to mid game, but is not as effective during the late game. However, Life Break remains a constant threat due to the slow and percentage-based damage.
Additional:
* Huskar can negate Dragon Knight's passive with multiple trades of Burning Spear.
Nyx Assassin
* Nyx Assassin wants to start ganking as soon as he gets his Vendetta. Keeping him Tracked prevents him from ganking, and thus from doing his job in the game.
* Nyx Assassin has a lot of armor and health regen, making the nuke damage from Shuriken Toss very good against him.
Additional:
* 
Track hinders Nyx Assassin's ganking and escaping attempts with Vendetta, making him an easy kill for gold as well.
* Bounty Hunter can also use Track on Nyx Assassin while he has Spiked Carapace active without getting stunned as Track deals no damage at all before using 
Shuriken Toss.
Huskar
* Huskar with Life Break
* Heroes that can remove the Track debuff with their skills:
* 
Abaddon with 
Aphotic Shield and Borrowed Time
* Huskar with Life Break
* 
Juggernaut with Blade Fury
* Legion Commander with 
Press the Attack
* 
Lifestealer with 
Rage and 
Infest
* Naga Siren with Mirror Image
* Omniknight with 
Heavenly Grace
* 
Oracle with 
Fortune's End and 
False Promise
* Phantom Lancer with 
Doppelganger
* Slark with Dark Pact
* Ursa with 
Enrage
* Weaver with 
Time Lapse
* 
Tidehunter with 
Kraken Shell when damage received reaches the threshold.
Huskar
* Huskar's high attack speed can counteract 
Fire Spirits, and easily destroy the 
Supernova.
Additional:
* Berserker's Blood will let Huskar easily face down a Supernova with increased attack speed.
* 
Icarus Dive may not be an easy escape from Huskar either as he can chase Phoenix during it with Life Break if Huskar times it right.
* However, Phoenix can buy items which can
Nyx Assassin
* Spiked Carapace reacts on any of the damage over time from Phoenix's abilities and can interrupt 
Sun Ray and Icarus Dive.
Huskar
* Life Break closes the distance between Huskar and Drow Ranger, dealing large amounts of damage and disabling Marksmanship.
* Berserker's Blood and Burning Spear allow Huskar to beat Drow Ranger directly and pile on damage.
Nyx Assassin
* Nyx Assassin has a lot of burst damage from his Impale, Mind Flare, 
Dagon, and the bonus damage from Vendetta. All of this damage is enough to kill Drow Ranger.
* Nyx Assassin is usually invisible most of the time thanks to his ability Vendetta, which allows him to gank Drow Ranger easily.
* However, 
Gust is extremely dangerous for Nyx Assassin, as it's silence can render Nyx Assassin unable to lock down Drow Ranger. And if Gust hits Nyx Assassin while he is invisible with Vendetta, Drow Ranger will be able to detect him and foil his ganking attempts on her because Gust reveals invisible units.
Huskar
* Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.
Nyx Assassin
* Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive 
Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious 
Stone Gaze.
* Mana Burn quickly destroys 
Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from 
Mystic Snake and Split Shot can trigger Spiked Carapace.
* 
Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Huskar
* Inner Fire can damage and disarm Chen's creeps.
* Burning Spear's high damage over time that grows stronger the more it stacks can force Chen to use Hand of God prematurely, potentially wasting a chance to save his allies during a teamfight.
* Berserker's Blood makes it impossible for Chen and his creeps to kill Huskar.
* Life Break can deal huge damage to Chen and slow him down.
Nyx Assassin
* Heroes with either magical, physical or pure damage burst can often kill Chen or his allies before he can use Hand of God: Lina, Luna, Techies, Shadow Fiend, 
Pugna, Nyx Assassin.
Huskar
* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: 
Lich, 
Crystal Maiden, Silencer, 
Keeper of the Light, Venomancer, etc.
Nyx Assassin
* Crystal Maiden has a very bad movement speed, so Impale is easy to land against her. Furthermore, even while trapped by Frostbite, Nyx Assassin can still cast Impale.
* Crystal Maiden has very low armor, so Vendetta is very effective.
* Nyx Assassin has two ways to stop Freezing Field, provided she doesn't get a Black King Bar. He can either pop Spiked Carapace and simply walk into the field, or he can use Impale to interrupt the field, since Crystal Maiden has to channel it.
Additional:
* Spiked Carapace easily interrupts 
Freezing Field.
* 
Frostbite's damage over time sets up an easy Spiked Carapace stun.
* Crystal Maiden is extremely fragile and dies quickly to Nyx Assassin's burst damage.
Huskar
* Axe, Bristleback, 
Centaur Warrunner, Spirit Breaker, Pudge, Huskar, 
Wraith King, Doom: These heroes are too tanky for Puck to burst down. Also, all of them have spells which can deal with and shut Puck down reliably.
Nyx Assassin
* 
Illusory Orb is easy to reflect with Spiked Carapace, either stunning Puck and setting up an easy Impale or forcing a premature 
Phase Shift.
* Puck is an intelligence hero that tends to build intelligence items, making it vulnerable to Mana Burn.
* An ill-timed Phase Shift can easily set Puck up to be stunned by Impale.
* Puck's low base armor and below average agility gain mean it is always susceptible to Vendetta.
Additional:
* Nyx Assassin can take advantage of every one of Puck's weaknesses. His entire skill set is very effective in countering Puck.
* Because Illusory Orb is such a slow moving projectile, Nyx Assassin can simply walk into the orb and activate Spiked Carapace, stunning Puck and setting up an easy Impale. This can be circumvented by using Phase Shift while the orb is traveling, however, that means that Puck cannot use Phase Shift to dodge any other skill nor use it to safely blink away from a fight.
* Puck is an intelligence hero that likes to build intelligence items such as Eul's Scepter of Divinity, Scythe of Vyse, and Dagon. This makes Mind Flare that much more deadly against Puck.
* An ill-timed Phase Shift can turn into an easy setup for Impale.
Huskar
* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: Lich, Crystal Maiden, Silencer, Keeper of the Light, Venomancer, etc.
Nyx Assassin
* Spiked Carapace can be used to reflect Illuminate damage and stun Keeper of the Light.
* Vendetta allows Nyx Assassin to follow Keeper of the Light around if he tries to split-push.
* Keeper of the Light is very squishy and will very quickly die to Vendetta and it's followup abilities.
Huskar
* 
Sprout will not protect Nature's Prophet from Huskar if he has already locked on with Life Break.
* Even a farmed Nature's Prophet is usually not durable enough to fight Huskar alone.
Nyx Assassin
* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin.
Huskar
* Heroes with spell immunity: Juggernaut, 
Pangolier, Huskar.
Nyx Assassin
* Nyx Assassin's Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* Mind Flare deals high damage due to Leshrac's high intelligence gain.
* Vendetta burns a large amount of Leshrac's essential mana pool.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Huskar
* Huskar can destroy Ember Spirit both on the line and in the game. It will be extremely difficult for Ember Spirit to finish off the creeps, because Huskar will not let him approach them, and if Ember Spirit does come up, Huskar just shuts him up with his Burning Spear and Ember Spirit will have to go to the base or bring himself treatment, or continue to stand and die. In all cases, Ember Spirit will go into negative
Additional:
* Ember Spirit does minimal damage to Huskar until the very late game.
* Huskar can destroy Ember Spirit both on the line and in the game. It will be extremely difficult for Ember Spirit to finish off the creeps, because Huskar will not let him approach them, and if Ember Spirit does come up, Huskar just shuts him up with his Burning Spear and Ember Spirit will have to go to the base or bring himself treatment, or continue to stand and die. In all cases, Ember Spirit will go into negative
Nyx Assassin
* With Vendetta, Nyx Assassin can move closely to Ember Spirit when he's farming with his Flame Guard and use Spiked Carapace with Impale to provide a reliable and long disable.
Additional:
* Spiked Carapace can be easily triggered by 
Flame Guard or Battle Fury, setting up a deadly Impale.
Huskar
* Heroes with abilities that reduce armor will make Huskar very vulnerable: Weaver, 
Dazzle, Bristleback, 
Vengeful Spirit.
Huskar
* Weaver cannot Time Lapse out of Huskar's burn damage.
Nyx Assassin
* Spiked Carapace allows Nyx to get an easy long-duration stun on Weaver once he uses Shukuchi, and then he can follow up with Impale.
* Vendetta works as a great setup for both Impale and Spiked Carapace and can deal decent damage to Weaver. Additionally he can neutralize The Swarm beetles due to his invisibility duration.
Huskar
* Huskar's burn damage from Burning Spear is incredibly strong against Templar Assassin as it completely cancels out her Refraction from the burning over time which results in making her very vulnerable to ganks and harassments, and in turn forcing her out of the lane.
Nyx Assassin
* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity, even if Batrider is focusing on other enemy hero.
Huskar
* Since Tidebringer has a 4 second cooldown, Kunkka has little availability to manfight Huskar.
Huskar
* Burning Spear's magical damage is very troublesome for Mars in the laning stage.
* Life Break's percentage-based magical damage bypasses Bulwark, and can also be used to jump in or out of Arena Of Blood.
Huskar
* Sunder can prevent Terrorblade's or an ally's death by swapping health, making damage-over-time abilities inefficient. Heroes that rely on damage-over-time abilities like Venomancer and Huskar will have a hard time against Sunder.
Huskar
* As Terrorblade's damage output comes mainly from direct attacks, he will struggle greatly against heroes who have abilities that give evasion, trigger on attack or which can disarm an enemy hero: Centaur Warrunner, 
Hoodwink, Huskar, Invoker, 
Leshrac with 
Nihilism from Aghanim's Scepter, Lifestealer with Aghanim's Scepter upgraded Infest, Pangolier, Phantom Assassin, Pugna, Techies, 
Windranger etc.
Nyx Assassin
* Nyx Assassin deals large amounts of pure damage with Vendetta and magical damage with Impale and Mind Flare, allowing him to ignore Terrorblade's armor and burst his low health pool down before he can use 
Sunder.
* Nyx Assassin commonly buys 
Urn of Shadows, Dagon and Meteor Hammer which deal magic damage that ignore Terrorblade's armor.
* However, Terrorblade is a natural Eye of Skadi and Black King Bar wielder, and once he gets those items, Nyx Assassin's solo kill potential against Terrorblade will be gone.
Nyx Assassin
* Nyx Assassin's high burst damage, excellent ganking potential and multiple disables pose a threat to Muerta at all stages of the game.
* Mind Flare allows Nyx Assassin to take advantage of Muerta's high intelligence and make a short work of her low health.
* Spiked Carapace and Vendetta allow Nyx to escape or initiate well against Muerta's low mobility.
* As with most retaliation based abilities, Spiked Carapace can easily take advantage of 
Gunslinger's stray shots.
* However, Muerta is a natural Black King Bar wielder. And if she succeeds to activate it before Nyx Assassin can ambush her, he will go down very quickly against Muerta as Spiked Carapace cannot pierce through debuff immunity at all.
Nyx Assassin
* Impale and Spiked Carapace can be used to cancel Dismember easily, and can even do so when Pudge uses it on Nyx Assassin, if timed correctly.
Huskar
* Heroes with high magical burst can easily kill Huskar when he is at low health: Lion, Lina, Skywrath Mage
Huskar
* Skywrath Mage's armor and agility gain is very low, so when Huskar's Burning Spears stack they can take him down very quickly at any point of the game.
* Berserker's Blood grants bonuses as Huskar uses Burning Spears to harass Skywrath Mage, granting him attack speed, magic resistance, and strength as health regen, making it possible that Huskar can harass Skywrath Mage out of lane and sustain through his magic burst through staying injured throughout lane, or even the game.
* Life Break allows Huskar to jump onto Skywrath Mage, closing the distance between them and busting him down so he cannot run. This can be combed with Inner Fire, adding a movement speed slow if Aghanim's Shard is applied so Skywrath Mage cannot escape.
Nyx Assassin
* Slow-moving projectiles: Skywrath Mage, 
Tinker, 
Necrophos
Additional:
* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* Mind Flare turns Skywrath Mage's high intelligence growth against him and deals heavy damage.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.
Nyx Assassin
* Mana Burn removes much-needed mana for 
Ball Lightning.
* Spiked Carapace triggers on 
Static Remnant for an easy stun.
Additional:
* Vendetta is capable of removing most of Storm Spirit's large mana pool, along with dealing heavy damage and quickly depleting his chances of escaping a gank or fight.
Huskar
* Life Break along with Burning Spear can quickly kill Razor before Static Link steals enough damage for Razor to take down Huskar.
* Berserker's Blood can make stealing Huskar's damage and using it against him somewhat dangerous, as Huskar will be able to inflict more and more Burning Spears rapidly.
Nyx Assassin
* Spiked Carapace stops Snapfire's 
Mortimer Kisses.
Huskar
* Life Break and Burning Spear usually kills Gyrocopter before he can do much damage to Huskar.
* Inner Fire applies a disarm on all enemies, which can be a hindrance to Gyrocopter.
Nyx Assassin
* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.
Huskar
* Magnus cannot manfight Huskar even with Empower, Berserker's Blood's high attack speed and health regeneration, combined with Huskar's high health and Burning Spear stacks will allow Huskar to kill Magnus before he can kill him.
* From a safe distance, Huskar can surprise and counter Magnus's initiation with Life Break and Burning Spear.
* Burning Spear also deals damage over time, disabling Blink Dagger and preventing him from initiating or escaping.
Huskar
* Earthshaker's stuns will rarely save him once Huskar has initiated on him with Life Break.
* A full initiation combo will not kill Huskar, only lower his health and increase his attack speed.
Huskar
* Huskar's Burning Spears chip through his low health pool quickly.Consequently, he is forced to either invest on health regen or abandon the lane.
* Reliant on magic damage, there is little he can do against Huskar.
* Huskar will usually kill him if he gets Life Break off,given Zeus' poor mobility.
Nyx Assassin
* 
Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel 
Life Drain, making him easy to hit with Impale.
Additional:
* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mind Flare will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Huskar
* Inner Fire can damage and disarm Enigma's eidolons, which can then be cleared out with Burning Spears.
* Huskar's Burning Spears can deal serious damage over time to Enigma during laning and teamfights, and it can also disable Blink Dagger for a long time.
* Berserker's Blood that provides Huskar with magic resistance and bonus health regeneration makes it difficult for Enigma to take down Huskar. Huskar is also a common 
Satanic wielder, which can help him recover from Enigma's 
Black Hole in case he survives it. Enigma's only source of dealing Pure Damage that can bypass Berserker's Blood. This forces Enigma to buy Silver Edge, the only item that can help him against Huskar's Berserker's Blood.
* However, Huskar does not have any way to cancel Black Hole outside from Aghanim's Scepter upgraded Life Break that can force Enigma to attack Huskar if used on him.
Nyx Assassin
* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Luna, 
Puck, Slark, Nyx Assassin, etc.
Additional:
* Enigma's uncontrollable damage from 
Malefice and 
Midnight Pulse make him easy to stun with Spiked Carapace.
* Black Hole can be easily interrupted by Impale or Spiked Carapace.
Huskar
* Clockwerk cannot go head-to-head with Huskar in Power Cogs, as Berserker's Blood and Life Break will destroy him faster than the other way around.
Additional:
* Clockwerk's abilities cannot handle Huskar in a one-on-one fight, even if he gets the jump on him.
Huskar
* Heroes with pure damage can kill Huskar when he inevitably gets low on health: 
Outworld Destroyer, Silencer.
Huskar
* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: Lich, Crystal Maiden, Silencer, Keeper of the Light, Venomancer, etc.
Nyx Assassin
* 
Last Word is extremely easy to reflect with Spiked Carapace for large amounts damage, due to triggering when Nyx Assassin casts a spell, but can still silence Nyx Assassin. It also has the added bonus of dealing more damage the more Intelligence Silencer has.
* 
Glaives of Wisdom quickly builds Silencer's Intelligence, making him a particularly prime target for Mana Burn.
* Silencer rarely builds survivability items, nor is he able to steal much Intelligence while surrounded by his team, and so is an excellent target for Vendetta.
* Silencer has no reliable way of dealing with a burrowed Nyx, and also lacks the ability to prevent Nyx from escaping with Vendetta,
Additional:
* Silencer is rather squishy and has poor mobility without items, making him an easy target for Nyx.
* Silencer's intelligence steal ability is a complete disadvantage against Nyx Assassin as Mind Flare will deal increasing damage for each point of intelligence Silencer has stolen, turning Silencer's intelligence steal against him.
Huskar
* Huskar jumps on the hero without any problems, throwing the 
Summon Spirit Bear away from him and forbidding him to beat, which knocks down the regeneration of Lone Druid from the 
Spirit Link ability, in addition, Huskar instantly deals fatal damage to Lone Druid, in some cases he does not even have time to squeeze the 
True Form
Additional:
* Huskar jumps on the hero without any problems, throwing the Summon Spirit Bear away from him and forbidding him to beat, which knocks down the regeneration of Lone Druid from the Spirit Link ability, in addition, Huskar instantly deals fatal damage to Lone Druid, in some cases he does not even have time to squeeze the True Form
Nyx Assassin
* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with Spiked Carapace.
* Vendetta can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.
Huskar
* Certain heroes can mess up with Pangolier's positioning and timing (especially if he intends to use Rolling Thunder during combat): Vengeful Spirit, Keeper of the Light, Huskar, Dark Seer
Huskar
* Burning Spears can put 
Monkey King's 
Tree Dance on cooldown.
Huskar
* Heroes who can take advantage of God's Strength being on cooldown are also not great matchups, such as Templar Assassin, 
Morphling and Huskar.
Nyx Assassin
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light, Dawnbreaker.
Huskar
* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: Lich, Crystal Maiden, Silencer, Keeper of the Light, Venomancer, etc.
Additional:
* Lich is going to have a hard time nuking Huskar because of his high health regeneration from Berserker's Blood.
* Lich is a squishy support without an escape mechanism, making Lich an easy kill thanks to Life Break and Burning Spear.
* Once Huskar has Armlet of Mordiggian, even a maxed out Frost Blast will struggle to finish Huskar off.
Nyx Assassin
* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin.
Nyx Assassin
* Heroes with either magical, physical or pure damage burst: 
Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Huskar
* Huskar's huge damage output and attack speed can get rid of Undying and Tombstone quickly.
Nyx Assassin
* Heroes that can pick you off: Clinkz, Nyx Assassin, Puck, Riki.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Nyx Assassin
* Spiked Carapace can stop Dawnbreaker's Solar Guardian which will eliminate her global presence and limits her movement around the map.
Additional:
* Spiked Carapace interrupts 
Starbreaker before Dawnbreaker has her Aghanim's Shard, as well as 
Solar Guardian during the initial channel, making her ineffective at joining and dealing damage in teamfights.
* The slow projectile and damage over time effect of 
Celestial Hammer makes it easy to stun Dawnbreaker if she attemps to engage or chase.
Huskar
* Heroes with abilities that reduce armor will make Huskar very vulnerable: Weaver, Dazzle, Bristleback, Vengeful Spirit.
Additional:
* Huskar struggles against heroes that output high physical damage due to his low armor. Vengeful Spirit's Wave of Terror and Vengeance Aura help increase the physical damage of her team.
Nyx Assassin
* Vendetta disables Vengeance Aura and allows him to attack Vengeful Spirit with Impale and Mind Flare.
* Spiked Carapace is easy to use against a Wave of Terror or Magic Missile.
Huskar
* Heroes who rely on basic attacks will suffer from Laser: Phantom Assassin, Wraith King, Huskar.
Nyx Assassin
* 
Heat-Seeking Missile allow easy Spiked Carapace stuns.
* As a fragile hero that relies on mana and intelligence items, Tinker is vulnerable to Mana Burn.
* Nyx Assassin's stuns can interrupt 
Rearm and leave Tinker helpless.
Additional:
* Nyx Assassin's whole skillset is good against Tinker:
* Impale prevents Tinker from blinding Nyx Assassin or fighting back, while giving Nyx' allies time to catch up to Tinker's position.
* Mind Flare generally deals more damage to intelligence based heroes like Tinker.
* Spiked Carapace can stun Tinker at a moment of Nyx Assassin's choosing if March of the Machines has been cast. It is also quite easy to time Spiked Carapace against Heat Seeking Missiles.
* Vendetta allows Nyx to approach Tinker in the trees or wait for him in common hiding spots and deal heavy damage to his low armor.
Huskar
* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, Silencer.
Additional:
* Outworld Destroyer can dodge Life Break with Astral Imprisonment, leaving him unharmed while Huskar loses HP.
* Sanity's Eclipse can deal massive damage to Huskar before he builds up his Berserker's Blood stacks due to Huskar's low mana pool.
Nyx Assassin
* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* 
Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed 
Sanity's Eclipse and/or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used Black King Bar beforehand.
Additional:
* Outworld Destroyer's high intelligence makes him a good target for Mind Flare.
* If timed correctly, Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.
Huskar
* 
Untouchable makes it near impossible to stack Burning Spears.
* 
Impetus' pure damage puts an instant end to Huskar's low-health brinkmanship.
Nyx Assassin
* Vendetta can deal great damage against her. However, it requires an direct attack, so Nyx Assassin may have difficulties applying Vendetta on her.
* Enchantress's lack of mobility makes her a primary target for ganking with Vendetta.
* Mind Flare can deal a great damage against her due to being an Intelligence hero.
* Spiked Carapace can reflect Impetus and stun Enchantress.
Additional:
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.
Huskar
* 
Windrun makes it impossible to hit Windranger with Burning Spears.
* Huskar cannot toggle Armlet of Mordiggian to regain health while taking constant damage from 
Focus Fire.
Additional:
* Windranger prevents Huskar from landing Burning Spears by using Windrun.
* Because Huskar tends to be at low health, Focus Fire and Powershot are good abilities against him.
Nyx Assassin
* Many of Nyx Assassin's abilities are good against Windranger.
* Impale is great for stunning Windranger and allowing additional disables to be landed.
* Mind Flare is useful against Windranger's decent intelligence growth.
* Spiked Carapace is easy to use against Powershot.
* Vendetta allows Nyx Assassin to sneak up on and deal massive damage to Windranger without giving Windranger a chance to use Windrun to evade it.
* Nyx Assassin's item build allows him to easily deal with Windranger.
Huskar
* Huskar’s low health play style put him at extreme risk to 
Sharpshooter's extreme damage. In addition, it breaks Berserker's Blood, nullifying Huskar's power source.
Nyx Assassin
* Nyx's Spiked Carapace can reflect the damage of Sharpshooter, instantly killing hoodwink. Nyx can also use Vendetta to position himself in such a way to screen allies from Sharpshooter and catch Hoodwink by surprise.
Huskar
* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.
Nyx Assassin
* Heroes with heavy early and mid-game magical damage are also problematic for Phantom Assassin due to being able to easily kill her before she can gain an item advantage over them: Lina, Necrophos, Nyx Assassin, 
Gyrocopter, Jakiro, 
Death Prophet.
Huskar
* Sniper just doesn't give Huskar a chance, as he always just keeps his opponents at a great distance. However, in such a game you will need to have a 
Concussive Grenade and a 
Hurricane Pike in order to avoid the Life Break of Huskar
Additional:
* Sniper just doesn't give Huskar a chance, as he always just keeps his opponents at a great distance. However, in such a game you will need to have a Concussive Grenade and a Hurricane Pike in order to avoid the Life Break of Huskar
Nyx Assassin
* 
Assassinate is easy to reflect with Spiked Carapace for massive damage.
* 
Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Huskar
* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: Lich, Crystal Maiden, Silencer, Keeper of the Light, Venomancer, etc.
Additional:
* Huskar can easily regenerate lost health from DoT spells through Berserker's Blood rendering them ineffective
* Venomancer has little armor and mobility, and rarely builds Linken's Sphere, so he is quite vulnerable to Life Break.
Huskar
* Husker is the kind of hero that likes to remain at low health, which is perfect for Queen of Pain to burst with Sonic Wave.
* She should be able to Blink away after he jumps on her with Life Break.
Nyx Assassin
* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.
Huskar
* Spirit Breaker's stuns pierce spell immunity, making him a good choice against heroes that heavily rely on Black King Bar; Huskar
Huskar
* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, Dazzle, Arc Warden, Lion, Huskar, Shadow Shaman, Visage, 
Undying, Jakiro.
Huskar
* Because Huskar tends to stay at low health to gain the maximum bonuses from Berserker's Blood, it makes him an exceptionally prime target for 
Reaper's Scythe.
Additional:
* Huskar is often at low health, making him easy prey for Reaper's Scythe.
* Ghost Shroud prevents Huskar from stacking Burning Spear, and if Heartstopper Aura stacks are active, can regenerate health lost to existing stacks.
Nyx Assassin
* The huge physical damage taken from Vendetta will force Necrophos to use Ghost Shroud, which is good for a followup with Dagon and 
Ethereal Blade, both of which are common items on Nyx Assassin.
* Using Ghost Shroud also sets Necrophos up for a Mind Flare or Impale.
Nyx Assassin
* Heroes who are entirely reliant on dealing physical damage and/or have very little to no area-of-effect abilities will make Underlord tickle and will have no effect against him thanks to his 
Atrophy Aura, and will also be unable to ambush Underlord and his team if Underlord chooses to use 
Fiend's Gate to get to a designated point of the map: Phantom Assassin, 
Terrorblade, Troll Warlord, 
Drow Ranger, Phantom Lancer, Chaos Knight, 
Sven, Wraith King, Bounty Hunter, 
Alchemist, Templar Assassin, Nyx Assassin, Bane.
Nyx Assassin
* Heroes with magical or pure damage output will not have any problems against Atrophy Aura at all: Luna, Lina, Jakiro, Pugna, Bane, 
Snapfire, 
Muerta, Nyx Assassin, Enigma, Tinker, Witch Doctor, 
Zeus, Crystal Maiden.
Huskar
* Warlock Golems do plenty of physical and pure damage to bring down Huskar when he is at low health. Warlock is always a hazard for Huskar to initiate by using Life Break, because Chaotic Offering can stun him instantly, even when Black King Bar is activated, and allows Warlock's team to gather their wit and retaliate.
* After using Life Break to jump in, Huskar will not have any means to escape Upheaval. Which since he is an attack-dependent hero, this will nullify his impact in fights.
Nyx Assassin
* Impale and Spiked Carapace interrupts Upheaval with ease.
* Warlock's low health pool, mobility, and high intelligence gain makes him a prime target for Nyx Assassin's burst damage.
Huskar
* Quas Exort Invoker has high physical damage in the form of Cold Snap and Forged Spirits that allows him to trade hits with Huskar.
* Although Huskar can dispel Cold Snap with Life Break.
* Sun Strike deals pure damage and pierces spell immunity, and Huskar tends to drain his HP, making him a susceptible target.
Nyx Assassin
* Nyx Assassin can simply activate Spiked Carapace while under many Invoker's abilities to stun him.
* Nyx Assassin takes advantage of Invoker's massive intelligence gain to do tons of damage using Mind Flare, as the spell does more damage based on the target's intelligence.
* Vendetta burns a large amount of Invoker's essential mana pool.
Huskar
*
Rage renders Lifestealer immune to the damage from Burning Spears.
Feast makes Lifestealer one of few heroes that can outlast Huskar in a one-on-one fight.
*
Nyx Assassin
*
Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if Vendetta is on cooldown. Nyx Assassin cannot counter 
Rage with Spiked Carapace because 
Rage gives Lifestealer spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
Open Wounds from 
Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. 
Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with 
Open Wounds.
Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with 
Dust of Appearance or a 
Gem of True Sight. 
Aghanim's Scepter upgraded 
Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. and Nyx Assassin cannot counter this with Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
Blade Fury, 
Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if 
Vendetta is on cooldown. Nyx Assassin cannot counter 
Rage with 
Spiked Carapace because 
Rage gives Lifestealer spell immunity. And besides 
Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
Open Wounds from 
Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. 
Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with 
Open Wounds.
Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with 
Dust of Appearance or a 
Gem of True Sight. And similarly to Juggernaut's 
Omnislash and 
Swiftslash from 
Aghanim's Scepter, 
Aghanim's Scepter upgraded 
Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. And Nyx Assassin cannot counter this with 
Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
*
*
* Overall, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.
Additional:
* Like with Juggernaut's
*
*
* Like with Juggernaut, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.