Invoker
* Broodmother can kill Invoker easily in the early game with her 
Spawn Spiderlings and her spiderlings.
* Broodmother is both an 
Orchid Malevolence and a 
Nullifier carrier. As she can farm it early, she can kill Invoker easily.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: 
Beastmaster, 
Broodmother, 
Chaos Knight, 
Lycan, 
Naga Siren, 
Nature's Prophet, 
Phantom Lancer, 
Shadow Shaman, 
Terrorblade, 
Visage, 
Warlock, 
Wraith King.
Invoker
* A good choice against Invoker, as it has some advantage with the help of abilities.
* With the 
Dissimilate, Voidspirit can evade Invoker's skills, going to another world where he does not receive damage. The same ability to run away or attack quickly.
* 
Astral Step moves quickly from point to point, which also reduces the Invoker's probability that he will hit him with skills and cause at least some damage.
Additional:
* A good choice against Invoker, as it has some advantage with the help of abilities.
* With the Dissimilate, Voidspirit can evade Invoker's skills, like 
Chaos Meteor or 
E.M.P., going to another world where he does not receive damage. The same ability to run away or attack quickly.
* Astral Step moves quickly from point to point, which also reduces the Invoker's probability that he will hit him with skills and cause at least some damage.
Io
* Heroes with either magical, physical or pure damage burst: 
Bane, 
Ember Spirit, 
Leshrac, 
Lina, 
Luna, 
Nyx Assassin, 
Phantom Assassin, 
Skywrath Mage, 
Tinker, 
Ursa, 
Void Spirit.
Invoker
* Earth Spirit is a dangerous foe to encounter for Invoker in the early stages of the game. Since Invoker needs to gain levels as fast as possible and is not very strong in the early game, Earth Spirit can use his incredible early game power to gank Invoker and ruin his game plan.
* Earth Spirit combines stuns and silences with his spells and can apply them from a great distance. This is bad for Invoker as he is dependent on a smart usage of his spells with 
Invoke and Earth Spirit can disrupt his combos easily.
Io
* Squishy heroes (
Io, 
Crystal Maiden, Lina...), as Earth Spirit can deal tons of damage with Magnetize.
Invoker
* Quas-Exort Invoker is also a good matchup due to the fact he has no 
Wex to run faster due to the movement impairment on his stealth. The 
Forge Spirit and 
Cold Snap combo doesn't harm her as well since you can drain Invoker's HP with Spirit Siphon which forces him to retreat.
* Silence also prevents Invoker from using Invoke or casting his main spells temporarily. There is no way Invoker can block it unless he has 
Eul's Scepter of Divinity to cyclone himself or has help from allies.
Io
* Heroes that are hard to gank: 
Axe, 
Death Prophet, Phantom Lancer
Invoker
* Heroes with silence: Death Prophet, 
Riki, 
Drow Ranger.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, 
Tusk, 
Clinkz, 
Sniper, 
Slark, Phantom Assassin, Void Spirit, 
Storm Spirit, Ember Spirit, 
Earth Spirit, 
Spirit Breaker.
Invoker
* Heroes with long lockdowns: Shadow Shaman, 
Legion Commander.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Invoker
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: 
Disruptor, Death Prophet, 
Enigma, 
Faceless Void, 
Invoker, 
Lich, 
Magnus, 
Mars, 
Medusa, 
Outworld Destroyer, 
Phoenix, 
Puck, 
Queen of Pain, 
Shadow Fiend, 
Treant Protector, 
Underlord, 
Winter Wyvern, 
Witch Doctor, 
Zeus.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Invoker
* 
Bounty Hunter and 
Slardar both have ultimates (
Corrosive Haze and 
Track) that reveal Invoker through Ghost Walk.
Io
* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:Crystal Maiden, 
Pugna, Skywrath Mage, Io, Witch Doctor, etc.
Invoker
* Lone Druid has a very large reserve of health against Invoker abilities, this allows him to survive a large number of attacks from Invoker and kill him, also 
Entangling Claws reveal invisibility from 
Ghost Walk, which allows the Lone Druid team to catch the popular QW-Invoker
Additional:
* Lone Druid has a very large reserve of health against Invoker abilities, this allows him to survive a large number of attacks from Invoker and kill him, also Entangling Claws reveal invisibility from Ghost Walk, which allows the Lone Druid team to catch the popular QW-Invoker
Io
* 
Living Armor can be used to save a hero from a Relocate gank.
Invoker
* 
Tidebringer pressures Invoker easily in lane due to Invoker's low health and armor in the early game.
Invoker
* Zeus greatly hinders Invoker on the line with his long-range abilities. QW- and QE-Invoker have a very long recharge on abilities, and Zeus' 
Arc Lightning ability recharges too quickly, which is why he quickly kills a pack of creeps and drives Invoker under his tower, punching and not letting finish off creeps
* 
Lightning Bolt and 
Thundergod's Wrath abilities reveal invisibility of enemies, for example Invoker invisibility from Ghost Walk ability
Additional:
* Zeus greatly hinders Invoker on the line with his long-range abilities. QW- and QE-Invoker have a very long recharge on abilities, and Zeus' Arc Lightning ability recharges too quickly, which is why he quickly kills a pack of creeps and drives Invoker under his tower, punching and not letting finish off creeps
* Lightning Bolt and Thundergod's Wrath abilities reveal invisibility of enemies, for example Invoker invisibility from Ghost Walk ability
Io
* 
Burning Barrage and 
Tar Bomb allow Clinkz to quickly kill Io due to its low armor.
* Clinkz iz a hero that very often goes for Orchid Malevolence, and its upgrade 
Bloodthorn. Alternatively, Clinkz also loves to buy 
Gleipnir. And if Clinkz has both of them, he will be able to root and silence Io and prevent him from escaping with either 
Tether or 
Relocate.
Io
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* 
Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys 
Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and 
Macropyre.
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Invoker
* Anti-Mage's mobility and magic resistance make him nearly impossible to kill alone.
* Invoker's spells cost a lot of mana, and Invoker himself has a lot of mana. This means Invoker and his team are vulnerable to 
Mana Void's heavy damage.
* 
Blink allows Anti-Mage to escape from Invoker's combo if he doesn't have disables.
Io
* 
Ensnare and 
Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* 
Rip Tide combined with illusions from 
Mirror Image often finish off Io before he can save himself.
* 
Spirits's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys 
Aghanim's Scepter, she can gain access to 
Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's 
Flaming Lasso.
* 
Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his tethered targed try to gank.
Additional:
* Ensnare and Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* Rip Tide combined with illusions from Mirror Image often finish off Io before he can save himself.
* Spirit's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys Aghanim's Scepter, she can gain access to Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's Flaming Lasso.
* Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his tethered targed try to gank.
Invoker
* 
Crippling Fear is a good way to shut down and gank Invoker in the early game..
* 
Void deals good damage to Invoker and makes escaping harder.
* With 
Hunter in the Night and Void, Invoker can't get away from Night Stalker and won't be able to catch him with Sun Strike during the night.
Invoker
* 
Rage grants immunity from Invoker's spells and can dispel most of the disables such as the armor loss from Forge Spirit and the constant stuns of Cold Snap.
Additional:
* Rage protects Lifestealer from all of Invoker's spells (except for 
Sun Strike).
Invoker
* 
Nether Ward on its own can greatly hinder Invoker from casting many of his abilities, at least until he gets a significant amount of HP or is under the protection of spell immunity from 
Black King Bar
* 
Life Drain provides True sight, revealing Invoker through Ghost Walk, and forcing him or his allies to use an ability or item to interrupt its channeling
* Outside of Nether Ward's range, Invoker shall have the advantage, as Invoker has Tornado to purge Pugna's 
Decrepify when it is used defensively, Tornado or Cold Snap to prevent Pugna from channeling Life Drain
* A poorly used Decrepify on Pugna's allies means Invoker's abilities can be used to deal more damage to them.
Additional:
* Because Invoker relies on casting a large amount of spells to contribute to fights, Nether Ward can force him to not cast anything at all or take a large amount of damage to cast spells.
Io
* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.
Additional:
* Grimstroke can catch Io and his ally easily with 
Soulbind as Io has a tendency to tether himself with an ally frequently.
* Io is highly vulnerable to disables. Hence, Grimstroke's 
Phantom's Embrace is a great ability to hinder Io's potential.
Io
* Lich's 
Chain Frost forces Io to either give up providing buff to his ally with Tether or suffer devastating damage with his tethered ally.
* Lich can easily use 
Sinister Gaze to disable Io from getting away with Tether or Relocate.
Io
* 
Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's 
Diabolic Edict, 
Lightning Storm and 
Pulse Nova abilities. Luna's 
Moon Glaives and 
Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Additional:
* Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse can be used to cancel both, Tether and Relocate.
* Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Io
* Fireblast is a good tool to interrupt Io during its escapes through Tether.
* Ignite can be one of the few spells with enough total damage to out-trade the sustained healing Io provides for its fellow laner.
* However, picking other supports that focus less on the laning phase is generally a better choice against Io.
Invoker
* Invoker is heavily dependent on his spells, making him useless during 
Global Silence, as well as interrupting Invoker during his combo.
* 
Arcane Curse is particularly deadly, because Invoker will continuously lose health if he keeps invoking and casting new spells.
* 
Last Word will silence Invoker when he casts Invoke, interrupting his combo.
Io
* Io is a hero who needs to be close to it's tethered target to make it effective, and that's where Leshrac gets the advantage thanks to many of his area-of-effect abilities.
* Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to both, Io and its tethered target.
Additional:
* Lightning Storm will usually hit both Io and his Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.
Invoker
* Time Walk can easily avoid Invoker's combo damage if doesn't have disables.
* Chronosphere will reveal Invoker during Ghost Walk.
* All of Invoker's hidden cooldowns are affected by Time Dilation, so Faceless Void can easily slow him down a lot.
Additional:
* 
Time Dilation prevents Invoker from further invoking for the entire duration of the debuff, as well as massively slowing Invoker based on the large amount of spells he has.
* 
Time Walk will completely negate Invoker's combo damage.
* If Invoker is caught in 
Chronosphere, he will most likely be the primary target due to the large teamfight contribution he can provide.
Io
* 
Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.
Io
* 
Thirst allows Bloodseeker to see where Io relocated to, should either Io or the tethered hero have low health.
* 
Rupture forces Io to stay in place, preventing it from using the Tether bonus movement speed to escape.
Invoker
* Queen of Pain usually outlanes Invoker, giving her team a significant early game advantage while Invoker is still farming.
* 
Blink allows Queen of Pain to escape from Invoker's combo if he doesn't have disables.
Invoker
* Templar Assassin can easily counter Invoker's last hitting process in the early game with 
Refraction. Refraction also negates the stun from Cold Snap, since it will need to deal damage in order to apply its stun.
* Additionally, Refraction completely blocks damage from Sun Strike should Invoker try to finish her off, provided she activate Refraction beforehand.
Io
* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.
Additional:
* 
Glimpse directly negates Relocate.
* 
Kinetic Field prevents Io from escaping with Tether.
* 
Static Storm can silence and damage both, Io and it's tethered target. And it can also mute both, Io and it's tethered target when upgraded with Aghanim's Scepter
Invoker
* Puck Outlanes Invoker with his abilities: 
Illusory Orb, 
Waning Rift finishing off all creeps on the line and getting a higher level than him
* Puck dodges Invoker's magic attacks with his abilities: Illusory Orb, 
Phase Shift in a fight, preventing Invoker from doing damage
Additional:
* Puck Outlanes Invoker with his abilities: Illusory Orb, Waning Rift finishing off all creeps on the line and getting a higher level than him
* Puck dodges Invoker's magic attacks with his abilities: Illusory Orb, Phase Shift in a fight, preventing Invoker from doing damage
Invoker
* In the early to mid game, Invoker is defenseless against Storm Spirit's ganking with 
Ball Lightning and Orchid Malevolence.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Invoker
* Heroes with mana burn: Nyx Assassin, Invoker, Outworld Destroyer, Pugna, 
Lion
Io
* 
Phantom Strike allows Phantom Assassin jump directly to Io.
* 
Coup de Grace can make a short work of Io's low health and armor.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Invoker
* Bounty Hunter and Slardar both have ultimates (Corrosive Haze and Track) that reveal Invoker through Ghost Walk.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Io
* Heroes whose abilities can affect multiple enemies at once: 
Dawnbreaker, Ember Spirit, Lina, Luna, 
Jakiro, Leshrac, Invoker.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Invoker
* Heroes with abilities which have a built-in spell immunity: 
Lifestealer, 
Juggernaut, 
Pangolier.
Invoker
* 
Astral Imprisonment allows Outworld Destroyer to save himself or ally from Invoker's combo, or remove Invoker from a fight temporarily.
* 
Arcane Orb's pure damage will deal a lot of damage against Invoker's mediocre strength gain.
* E.M.P. is useless against Outworld Destroyer by activating 
Equilibrium.
* However, be aware that 
Sanity's Eclipse will most likely not deal any damage at all, due to Invoker's high intelligence gain compared to Outworld Destroyer's.
Invoker
* Any heroes with high intelligence, such as Invoker and Pugna.
Io
* Ice Blast prevents Io from healing an ally with Tether and prevents healing from 
Overcharge
* Io is a common 
Mekansm builder which is useless if he is affected by Ice Blast.
Additional:
* 
Ice Blast prevents Io from healing the target.
* Ancient Apparition can easily harass Io on lane with 
Chilling Touch due to it's high range and damage. This can get even worse if Ancient Apparition buys Aghanim's Scepter and combines it with items that can give him bonus attack damage and attack speed.
* Chilling Touch combined with 
Ice Vortex makes it nearly impossible for Io to escape from 
Cold Feet. Ice Vortex can also make Io and it's tethered target more vulnerable to Ancient Apparition and his allies's magical damage.
Invoker
* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, 
Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.
Io
* 
Poison Touch allows Dazzle to harass both, Io and it's tethered target on lane. Aghanim's Shard upgraded Poison Touch can also hex both, Io and it's tethered target, preventing them from escaping with Relocate, and also disarming them, silencing them, muting them and rendering them helpless against Dazzle and his allies.
* Io's damage output is one of the weakest, therefore Dazzle will have plenty of time to save an ally with 
Shallow Grave from gank by Io and it's tethered target.
* 
Shadow Wave will always hit both, Io and it's tethered target if they are near the ally Dazzle uses Shadow Wave on, while healing Dazzle's allies near them. Aghanim's Scepter upgraded Shadow Wave can bounce on both, Io and it's tethered target, causing them both to take damage and to be attacked by Dazzle. And unlike Io who doesn't get healed while using Tether, Shadow Wave will always heal Dazzle no matter on which of his allies he uses it on.
* 
Bad Juju will cause both, Io and it's tethered target to lose armor every time Dazzle casts a spell while strengthening armor of Dazzle's allies.
Additional:
* Poison Touch allows Dazzle to harass both, Io and it's tethered target on lane. Aghanim's Shard upgraded Poison Touch can also hex both, Io and it's tethered target, preventing them from escaping with Relocate, and also disarming them, silencing them, muting them and rendering them helpless against Dazzle and his allies.
* Io's damage output is one of the weakest, therefore Dazzle will have plenty of time to save an ally with Shallow Grave from gank by Io and it's tethered target.
* Shadow Wave will always hit both, Io and it's tethered target if they are near the ally Dazzle uses Shadow Wave on, while healing Dazzle's allies near them. Aghanim's Scepter upgraded Shadow Wave can bounce on both, Io and it's tethered target, causing them both to take damage and to be attacked by Dazzle. And unlike Io who doesn't get healed while using Tether, Shadow Wave will always heal Dazzle no matter on which of his allies he uses it on.
* Bad Juju will cause both, Io and it's tethered target to lose armor every time Dazzle casts a spell while strengthening armor of Dazzle's allies.
Invoker
* Some heroes with extreme range, like Zeus, Invoker or 
Clockwerk, can snipe your allies from anywhere after your Grave has expired.
Invoker
* 
Blade Fury, similar to Rage, grants immunity to Invoker's spells and can dispel some debuffs as well.
* 
Omnislash renders Juggernaut invulnerable to Invoker's spells and can easily take Invoker down.
Additional:
* Juggernaut's instant spell immunity from Blade Fury. helps him dodge Invoker's combos. He can dispel the disables from Cold Snap and 
Deafening Blast and dodge the damage from Chaos Meteor, as well as walk through 
Ice Wall.
* Juggernaut's high DPS allows him to kill split pushing Forge Spirit(s) effortlessly, and his high armor prevents them from being a threat to him.
* However, Invoker can hit Juggernaut with Sun Strike through Blade Fury, making the 
Tornado and Sun Strike combo a threat if he does not dodge Tornado.
Io
* Heroes with abilities that can save teammates are also effective such as 
Shadow Demon, 
Dazzle, 
Oracle, Bane, Pugna, Tusk, Winter Wyvern, Io, Underlord, Treant Protector and 
Keeper of the Light.
Io
* Terrorblade can easily take advantage of Io's weak durability with 
Reflection and 
Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from 
Conjure Image and 
Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with 
Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and it's Tethered target to escape with Relocate besides 
Terror Wave from Aghanim's Scepter.
Additional:
* Terrorblade can easily take advantage of Io's weak durability with Reflection and Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from Conjure Image and Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and it's Tethered target to escape with Relocate besides Terror Wave from Aghanim's Scepter.
Invoker
* Heroes who can summon illusions and summons because Terrorblade has no abilities to deal with multiple enemies at once outside Reflection: Shadow Shaman, Naga Siren, Broodmother, Lycan, Enigma, Chaos Knight, Phantom Lancer, Shadow Demon, 
Dark Seer, Nature's Prophet, Invoker, 
Morphling, Visage, 
Grimstroke with Aghanim's Scepter.
Invoker
* 
Doom completely takes Invoker out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Additional:
* Doom is a good way to shut down Invoker, preventing from casting spells and using items for a lengthy time, thus forcing him to invest on 
Linken's Sphere.
Io
* Heroes with the ability to heal allies, or those with good defensive abilities: 
Chen, Dazzle, Io, Oracle, 
Omniknight, Witch Doctor, Winter Wyvern, 
Abaddon, etc.
Invoker
* Any hero with a low HP pool is easy for Tinker to nuke down: Crystal Maiden, 
Enchantress, 
Gyrocopter, Lion, Riki, 
Techies, Terrorblade, 
Necrophos, Invoker.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Invoker
* Tinker is relatively helpless against Invoker, as his 
Rearm and 
Boots of Travel can be easily interrupted by Invoker's long range disables, even if he blinks away.
Invoker
* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and 
Sand King.
Io
* Tether helps Io escape from Earthbind even if Meepo has Blink Dagger.
* Io's Spirits can pressure Meepo while laning and will usually hit at least one of his clones.
Invoker
* Cold Snap can prevent Timbersaw from using both Timber Chain and Chakram due to the frequent stuns interrupting the lengthy cast animations, as well as stopping him mid-chain. This can negate Timbersaw's attempts to escape or dole out extra ability damage.
* Later in the game, Invoker's heavy magical and pure damage can be difficult to avoid, meaning Timbersaw's armor is less useful.
Invoker
* Invoker is a big problem for Tiny the whole game because of its multiple disables. For example, the Cold Snap ability can catch an attack from Tiny's hand by surprise, because it becomes slower with the pumping of 
Grow. has a giant deceleration, creating a condition for the kite, which Tiny is very afraid of. In addition, Invoker has a Deafening Blast that disables Tiny's main weapon - strong blows from the hand
Additional:
* Invoker is a big problem for Tiny the whole game because of its multiple disables. For example, such as Tornado + E.M.P. create unrealistic conditions for Tiny with mana, which is very necessary for Tiny at least for some attacks in a fight. The Cold Snap ability can catch an attack from Tiny's hand by surprise, because it becomes slower with the pumping of Grow. has a giant deceleration, creating a condition for the kite, which Tiny is very afraid of. In addition, Invoker has a Deafening Blast that disables Tiny's main weapon - strong blows from the hand
Invoker
* E.M.P. allows Invoker to burn Medusa's mana to weaken 
Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.
Io
* Io can escape from Pit of Malice with Tether or Relocate.
* Relocate can counter Dark Rift's split pushing.
Io
* Tether and Overcharge makes it much harder for Pudge to kill a target with 
Meat Hook, and Relocate can save the Io's ally while 
Dismember is being channeled.
Invoker
* 
Quas-
Exort Invoker can win the mid lane easily against Alchemist because Quas regeneration will nullify Acid Spray's damage over time and Exort damage bonus will allow Invoker to out last hit Alchemist.
Invoker
* Invoker's numerous area-of-effect abilities can interrupt Primal Beast, especially while he is in the middle of a team fight, where Primal Beast thrives. (Tornado, Cold Snap, and Ice Wall all help to disable Primal Beast and control him from a distance.
* E.M.P. disintegrates Primal Beast's low mana pool.
* However, Invoker is quite a slow-paced hero and not particularly known for being survivable against a rampaging Primal Beast with Black King Bar.
Io
* Phoenix's limit AoE, damage-over-time abilities give Io plenty of time to save allies with Relocate.
Invoker
* Tornado allows Invoker to purge Necrophos's 
Ghost Shroud, nullifying any benefits he could get out of it
* E.M.P. allows Invoker to burn Necrophos's mana, preventing him from using his abilities constantly
Invoker
* Quas Exort Invoker has high physical damage in the form of Cold Snap and Forged Spirits that allows him to trade hits with Huskar.
* Although Huskar can dispel Cold Snap with Life Break.
* Sun Strike deals pure damage and pierces spell immunity, and Huskar tends to drain his HP, making him a susceptible target.
Invoker
* Invoker's Forge Spirit can negate 
Flux.
* Provided he does a right combo with Chaos Meteor, Invoker can easily burst down Arc Warden (plus his clone if he spawns it.)
* An early Orchid Malevolence can shut down Arc Warden pretty hard, especially when Invoker has a good lane against him if he kills him early on.
* Deafening Blast and Ice Wall limit's Arc Wardens mobility and damage, crippling him greatly.
Invoker
* Heroes with high magical or pure damage will bypass Bulwark: 
Timbersaw, 
Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.
Invoker
* Heroes with naturally low mana can be easily shut down by E.M.P.: 
Sven, 
Tiny, Wraith King, Omniknight
Invoker
* Heroes with long animations can be frequently interrupted with Cold Snap: 
Earthshaker, 
Monkey King, Shadow Fiend Lina
Invoker
* Heroes who can clear the waves of Enigma's Eidolons: Lina, Luna, Dawnbreaker, Jakiro, Shadow Shaman, Death Prophet, Keeper of the Light, Invoker, Leshrac, Puck.
Io
* 
Take Aim and 
Assassinate allow Sniper to reach Io even if it stays in the backline.
Invoker
* Invoker's arsenal of magical spells are troublesome for Sniper who has low HP and high armor, which does not benefit him much against Invoker.
* Besides magical damage, he can be disarmed and repeatedly mini-stunned with Cold Snap, preventing him from reacting.
* Leveling Quas can allow Invoker to lane effectively against Sniper despite right-click harassment.
Io
* Heroes with high mobility can approach Sniper: 
Anti-Mage, Earth Spirit, Io, Nature's Prophet, Pangolier, Puck, Queen of Pain and most notably Riki.
Invoker
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, 
Venomancer, 
Elder Titan, Faceless Void, 
Rubick, Keeper of the Light, Pugna, Invoker, 
Spectre, 
Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, 
Razor, 
Huskar, 
Batrider, 
Kunkka, 
Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.
Invoker
* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina
Invoker
* Heroes with naturally low mana can be easily shut down by E.M.P.: Sven, Tiny, Wraith King, Omniknight
Additional:
* Tornado dispels Heavenly Grace and Guardian Angel from multiple targets.
* Guardian Angel is generally useless against Invoker as he primarily relies on magical damage.
* E.M.P. depletes Omniknight's already small mana pool.
* Invoker's many disables keep Omniknight's team occupied until Guardian Angel times out.
Invoker
* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.
Invoker
* Invoker's multiple spells can lock down Undying and disable him from doing much.
Invoker
* Invoker's E.M.P. is extremely effective against Earthshaker due to his low natural mana.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Invoker
* Ember Spirit has a small mana pool, which is why QW-Invoker can burn it out very effectively with his own E.M.P., do not give Ember Spirit the opportunity to play with his abilities and cause damage with them in a fight.
* QW-Invoker Destroys Ember Spirit's 
Flame Guard with his own Tornado, which is why Ember Spirit cannot defend against Invoker's strong magic damage.
Additional:
* Ember Spirit has a small mana pool, which is why QW-Invoker can burn it out very effectively with his own E.M.P., do not give Ember Spirit the opportunity to play with his abilities and cause damage with them in a fight.
* QW-Invoker Destroys Ember Spirit's Flame Guard with his own Tornado, which is why Ember Spirit cannot defend against Invoker's strong magic damage.
Invoker
* Heroes with silence: Death Prophet, Riki, Drow Ranger.
Io
* Drow Ranger's lack of escape abilities makes her an easy target for Relocate ganks.
Invoker
* Heroes with long lockdowns: Shadow Shaman, Legion Commander.
Io
* 
Duel is very effective against Io due to its low health and armor.
Invoker
* Invoker's spells will disable and destroy Legion Commander while she's locked in a Duel.
Io
* Tethered heroes are much harder for Legion Commander to kill in Duels.
* Relocate can cancel Duels and save allies.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Nature's Prophet is extremely easy to gank with Relocate while he's split pushing.
* Tether on a friendly unit can destroy Nature Prophet's trees should he surround himself with 
Sprout as a defense.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Invoker
* E.M.P. allows Invoker to burn Wraith King's mana to prevent 
Reincarnation from triggering (only until Wraith King gets his Aghanim's Shard).
* Ice Wall and Cold Snap are particularly crippling for Wraith King as they allow to kite him very effectively, preventing him from dealing melee attack damage.
Additional:
* Invoker can drain Wraith King's mana with E.M.P., preventing him from reincarnating unless Wraith King has his Aghanim's Shard.
* Even if Wraith King survives and reincarnates, Invoker still has an arsenal of spells to lockdown Wraith King, including an easily setup Ice Wall.
* Tornado applies an area dispel to clear skeletons.
Io
* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Additional:
* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Invoker
* QW-Invoker perfectly resists Batrider in his attacks, since Batrider has a small mana reserve and depends very much on him - E.M.P. perfectly allows Invoker to deprive her, and he also has the abilities of Tornado and Cold Snap, which can help him fend off his attack, and possibly even kill along with his team
Additional:
* QW-Invoker perfectly resists Batrider in his attacks, since Batrider has a small mana reserve and depends very much on him - E.M.P. perfectly allows Invoker to deprive her, and he also has the abilities of Tornado and Cold Snap, which can help him fend off his attack, and possibly even kill along with his team
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Invoker
* Heroes with long animations can be frequently interrupted with Cold Snap: Earthshaker, Monkey King, Shadow Fiend Lina
Invoker
* 
Corrosive Skin makes Viper receive less damage from Invoker's spells
* Viper can harass Invoker with his 
Poison Attack in the early game.
* 
Viper Strike and Poison Attack can kill Invoker easily if Ghost Walk is on cooldown.
Invoker
* Ice Wall and Ghost Walk can be used to kite and escape from Viper.
* Chaos Meteor and Sun Strike deal heavy damage and can quickly bring Viper down.
* Cold Snap, Tornado, and Deafening Blast are powerful disables that reduce Viper's effectiveness.
* E.M.P. burns Viper's limited mana pool, reducing his potential poison damage.
* Forge Spirits can melt Viper's armor and reduce his durability.
Io
* 
Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* 
Greater Bash and 
Nether Strike is devastating due to Io's low armor, and can even knock it away from tethered target.
Invoker
* Ice Wall can slow down Charge of Darkness in its tracks at max level, allowing counterplays such as Cold Snap to end the charge, bursting down with Tornado, Meteor, and right clicks, or even teleporting back to spawn to drag Spirit Breaker into the fountain.
* Cold Snap (if timed right) and Invoker's other disables like Tornado can interrupt Charge of Darkness, especially since Charge is telegraphed by the symbol appearing over head.
Additional:
* Cold Snap allows Invoker to interrupt Charge of Darkness and Nether Strike.
* Tornado's long range can be used to cancel Charge of Darkness.
* Deafening Blast prevents Spirit Breaker from right clicking and thus proccing his Greater Bash.
Io
* 
Cold Embrace can render the extra attack speed from Overcharge meaningless.
* 
Splinter Blast and 
Winter's Curse are very affective against Io, as it has to stay close to its tethered hero.
Invoker
* Cold Embrace is the perfect setup for all his nukes - Chaos Meteor, E.M.P. and especially global Sun Strike.
Invoker
* Nyx Assassin can simply activate
Spiked Carapace while under many Invoker's abilities to stun him.
Mind Flare, as the spell does more damage based on the target's intelligence.
Vendetta burns a large amount of Invoker's essential mana pool.
* Nyx Assassin takes advantage of Invoker's massive intelligence gain to do tons of damage using
*
Io
* Heroes with either magical, physical or pure damage burst:
Bane, 
Ember Spirit, 
Leshrac, 
Lina, 
Luna, 
Nyx Assassin, 
Phantom Assassin, 
Skywrath Mage, 
Tinker, 
Ursa, 
Void Spirit.