Io
* 
Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.
Dark Willow
* Quill Spray's constant AoE damage will hit Dark Willow even in Shadow Realm. Its automatic damage will hurt her if she tries to get close and use Bedlam.
Io
* Heroes with either magical, physical or pure damage burst: 
Bane, 
Ember Spirit, 
Leshrac, 
Lina, 
Luna, 
Nyx Assassin, 
Phantom Assassin, 
Skywrath Mage, 
Tinker, 
Ursa, 
Void Spirit.
Dark Willow
* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* 
Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.
Io
* 
Phantom Strike allows Phantom Assassin jump directly to Io.
* 
Coup de Grace can make a short work of Io's low health and armor.
Dark Willow
* Heroes with high burst damage and 
Black King Bar can take down Dark Willow quickly: Phantom Assassin, 
Sven, 
Wraith King
Io
* Heroes that can easily bypass Io's allies to get to Io: 
Riki, 
Tusk, 
Clinkz, 
Sniper, 
Slark, Phantom Assassin, Void Spirit, 
Storm Spirit, Ember Spirit, 
Earth Spirit, 
Spirit Breaker.
Dark Willow
* 
Smoke Screen prevents Dark Willow from using her abilities, rendering her defenseless and unable to deal any serious damage.
* 
Blink Strike lets Riki jump past Bramble Maze.
Io
* Heroes that are hard to gank: 
Axe, 
Death Prophet, 
Phantom Lancer
Dark Willow
* 
Berserker's Call forces Dark Willow to attack, cancelling Shadow Realm.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Dark Willow
* 
Ancient Seal instantly shuts down Dark Willow's abilities, rendering her defenseless against his high burst damage spells, while she cannot cast spells of her own.
* 
Mystic Flare deals immense burst damage in an area, damaging Dark Willow through Shadow Realm.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Dark Willow
* 
Ball Lightning allows Storm Spirit to bypass Bramble Maze into the backline, and zip back into battle if he gets hit by Terrorize.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Dark Willow
* 
Flame Guard blocks Dark Willow's magical burst damage, and harms her if she tries to get close to attack with Bedlam.
* 
Sleight of Fist and 
Fire Remnant makes it hard for Dark Willow to fully disable Ember Spirit.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: 
Beastmaster, 
Broodmother, 
Chaos Knight, 
Lycan, 
Naga Siren, 
Nature's Prophet, Phantom Lancer, 
Shadow Shaman, 
Terrorblade, 
Visage, 
Warlock, Wraith King.
Dark Willow
* Heroes with high burst damage and Black King Bar can take down Dark Willow quickly: Phantom Assassin, Sven, Wraith King
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer
Dark Willow
* Heroes who can silence will shut down Dark Willow entirely: Death Prophet, 
Silencer, 
Drow Ranger
Io
* 
Living Armor can be used to save a hero from a Relocate gank.
Dark Willow
* 
Fortune's End not being disjointable is almost an ensured disable if Dark Willow tries to escape with Shadow Realm. Dispels Cursed Crown and Terrorize.
* 
Fate's Edict negates all her magic damage in case she catches a single hero.
* 
False Promise's strong dispel removes Dark Willow's disables.
Additional:
* Fortune's End can easily dispel 
Cursed Crown before it times out and stuns. He can also save a stunned ally with False Promise.
* Fate's Edict can easily negate 
Bedlam's over-time damage, since the spell provides no form of control. Similarly, he can also negate the magic burst from 
Shadow Realm.
* Fortune's End can dispel the fear effect from 
Terrorize, and it can remove the root from 
Bramble Maze if cast quick enough. Be mindful that Fortune's End only dispels your allies' debuffs on the primary target.
Dark Willow
* 
Magnetic Field lets Arc Warden or allies evade Dark Willow's shadow realm attacks. The duration of the evasion can be extended with the clone.
* 
Spark Wraith also exploits Dark Willow's low mobility.
Io
* 
Burning Barrage and 
Searing Arrows allow Clinkz to quickly kill Io due to its low armor.
* Clinkz iz a hero that very often goes for 
Orchid Malevolence, and its upgrade 
Bloodthorn. Alternatively, Clinkz also loves to buy 
Gleipnir. And if Clinkz has both of them, he will be able to root and silence Io and prevent him from escaping with either 
Tether or 
Relocate.
Io
* 
Ensnare and 
Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* 
Rip Tide combined with illusions from 
Mirror Image often finish off Io before he can save himself.
* 
Spirits's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys 
Aghanim's Scepter, she can gain access to 
Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's 
Flaming Lasso.
* 
Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his tethered targed try to gank.
Additional:
* Ensnare and Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* Rip Tide combined with illusions from Mirror Image often finish off Io before he can save himself.
* Spirit's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys Aghanim's Scepter, she can gain access to Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's Flaming Lasso.
* Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his tethered targed try to gank.
Io
* Ice Blast prevents Io from healing an ally with Tether and prevents healing from 
Overcharge
* Io is a common 
Mekansm builder which is useless if he is affected by Ice Blast.
Additional:
* 
Ice Blast prevents Io from healing the target.
* Ancient Apparition can easily harass Io on lane with 
Chilling Touch due to it's high range and damage. This can get even worse if Ancient Apparition buys Aghanim's Scepter and combines it with items that can give him bonus attack damage and attack speed.
* Chilling Touch combined with 
Ice Vortex makes it nearly impossible for Io to escape from 
Cold Feet. Ice Vortex can also make Io and it's tethered target more vulnerable to Ancient Apparition and his allies's magical damage.
Dark Willow
* 
Last Word and 
Arcane Curse have the range to hit Dark Willow beyond Bramble Maze.
* 
Global Silence renders Dark Willow useless in teamfights.
Io
* Lich's 
Chain Frost forces Io to either give up providing buff to his ally with Tether or suffer devastating damage with his tethered ally.
* Lich can easily use 
Sinister Gaze to disable Io from getting away with Tether or Relocate.
Io
* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.
Additional:
* Grimstroke can catch Io and his ally easily with 
Soulbind as Io has a tendency to tether himself with an ally frequently.
* Io is highly vulnerable to disables. Hence, Grimstroke's 
Phantom's Embrace is a great ability to hinder Io's potential.
Io
* Fireblast is a good tool to interrupt Io during its escapes through Tether.
* Ignite can be one of the few spells with enough total damage to out-trade the sustained healing Io provides for its fellow laner.
* However, picking other supports that focus less on the laning phase is generally a better choice against Io.
Dark Willow
* 
Rage protects and dispels all of Dark Willow's abilities.
Additional:
* Rage protects Lifestealer from all of Dark Willow's abilities.
Io
* 
Cold Embrace can render the extra attack speed from Overcharge meaningless.
* 
Splinter Blast and 
Winter's Curse are very affective against Io, as it has to stay close to its tethered hero.
Dark Willow
* 
Counterspell negates Dark Willow's high magic burst damage. Its active blocks Cursed Crown.
* 
Blink allows Anti-Mage to dodge Terrorize during its long cast animation, as well as avoiding the obstacles from Bramble Maze. On the other hand, if Anti-Mage gets caught inside Bramble Maze, he's unable to Blink away.
* Dark Willow's chained magic burst requires a lot of mana, setting her up for damaging 
Mana Voids.
Io
* Io is a hero who needs to be close to it's tethered target to make it effective, and that's where Leshrac gets the advantage thanks to many of his area-of-effect abilities.
* 
Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* 
Diabolic Edict and 
Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to both, Io and its tethered target.
Additional:
* Lightning Storm will usually hit both Io and his Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.
Dark Willow
* All of Puck's abilities are area-targeted, and will hit Dark Willow when she uses Shadow Realm.
* 
Illusory Orb allows Puck to bypass Bramble Maze, close the gap and silence Dark Willow with 
Waning Rift.
* 
Phase Shift helps Puck dodge attacks charged by Shadow Realm, and is easily timed against Terrorize's long cast time.
Io
* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.
Additional:
* 
Glimpse directly negates Relocate.
* 
Kinetic Field prevents Io from escaping with Tether.
* 
Static Storm can silence and damage both, Io and it's tethered target. And it can also mute both, Io and it's tethered target when upgraded with Aghanim's Scepter
Io
* 
Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's Diabolic Edict, Lightning Storm and Pulse Nova abilities. Luna's 
Moon Glaives and 
Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Additional:
* Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse can be used to cancel both, Tether and Relocate.
* Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Io
* Terrorblade can easily take advantage of Io's weak durability with 
Reflection and 
Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from 
Conjure Image and 
Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with 
Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and it's Tethered target to escape with Relocate besides 
Terror Wave from Aghanim's Scepter.
Additional:
* Terrorblade can easily take advantage of Io's weak durability with Reflection and Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from Conjure Image and Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and it's Tethered target to escape with Relocate besides Terror Wave from Aghanim's Scepter.
Io
* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying 
Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Additional:
* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes whose abilities can affect multiple enemies at once: 
Dawnbreaker, Ember Spirit, Lina, Luna, 
Jakiro, Leshrac, 
Invoker.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Dark Willow
* Heroes with high burst damage and Black King Bar can take down Dark Willow quickly: Phantom Assassin, Sven, Wraith King
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:
Crystal Maiden, 
Pugna, Skywrath Mage, 
Io, 
Witch Doctor, etc.
Io
* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Io
* Squishy heroes (Io, Crystal Maiden, Lina...), as Earth Spirit can deal tons of damage with Magnetize.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* 
Take Aim and 
Assassinate allow Sniper to reach Io even if it stays in the backline.
Io
* Heroes with high mobility can approach Sniper: 
Anti-Mage, Earth Spirit, Io, Nature's Prophet, 
Pangolier, 
Puck, 
Queen of Pain and most notably Riki.
Dark Willow
* 
Blade Fury dispels most of Dark Willow's abilities, allowing Juggernaut to pass through Bramble Maze and cancel out Cursed Crown before the stun occurs.
* However, Dark Willow can tank 
Omnislash with Shadow Realm. As she is a valid target, but invulnerable to right clicks.
Additional:
* None of Dark Willow's spells pierce Spell Immunity, making Blade Fury a good counter against her. Additionally, it dispels Cursed Crown and Bramble Maze.
* Dark Willow is generally fragile, which results in Omnislash being devastating against her.
* However, if Shadow Realm is activated during Omnislash, then the attack damage is negated (though Omnislash can still jump to other enemies).
Io
* Heroes with abilities that can save teammates are also effective such as 
Shadow Demon, 
Dazzle, 
Oracle, Bane, Pugna, Tusk, 
Winter Wyvern, Io, 
Underlord, 
Treant Protector and 
Keeper of the Light.
Io
* Tether helps Io escape from Earthbind even if Meepo has Blink Dagger.
* Io's Spirits can pressure Meepo while laning and will usually hit at least one of his clones.
Dark Willow
* Casting Bramble Maze on top of Meepo guarantees a root, as it is nearly impossible to leave the thorns with all of Meepo's clones.
* Terrorize and Cursed Crown offer great disables against the grouped Meepos and can prevent them from using 
Poof to escape.
Dark Willow
* Bramble Maze prevents Timbersaw from 
Timber Chaining away without getting rooted.
* Cursed Crown can still catch Timbersaw if he Timber Chains away.
* 
Reactive Armor offers little protection against Dark Willow's high magical damage.
Dark Willow
* Terrorize forces Monkey King out of 
Wukong's Command.
Dark Willow
* 
Windrun does not protect Windranger from Cursed Crown's stun or Dark Willow's magical nukes.
* 
Focus Fire cannot target Dark Willow in Shadow Realm and will be interrupted if targeted earlier, wasting the ultimate.
Additional:
* Windrun does not protect Windranger from Cursed Crown stun or Dark Willow's magical nukes.
* Focus Fire cannot target Dark Willow in Shadow Realm and will be interrupted if targeted earlier, wasting the ultimate.
Io
* Io can escape from Pit of Malice with Tether or Relocate.
* Relocate can counter Dark Rift's split pushing.
Dark Willow
* Bramble Maze will very likely catch Marci midair, disabling Marci's chasing/fleeing ability.
* Shadow Realm prevents Marci from bursting Willow down since she relies on physical attacks and unit target spells. With Aghanim's Scepter, Willow can hit Marci while Marci can't hit Willow.
* Bedlam and 
Eul's Scepter of Divinity allows Willow to manfight if Marci initiates with Rebound.
* Terrorize and Cursed Crown combo can waste Marci's ultimate for almost half of its duration.
Dark Willow
* Terrorize forces Faceless Void out of 
Chronosphere.
Io
* Phoenix's limit AoE, damage-over-time abilities give Io plenty of time to save allies with Relocate.
Dark Willow
* Terrorize, Bedlam and Cursed Crown ignore Pierce the Veil.
* Shadow Realm can be used to escape Pierce the Veil's high damage, as Muerta cannot attack her while she is in it.
Dark Willow
* Dark Willow's burst damage and stun prevents Troll Warlord from approaching her until he has Black King Bar.
* Troll Warlord's lack of burst damage makes it hard for him to kill Dark Willow before she slips into Shadow Realm.
Io
* Heroes with the ability to heal allies, or those with good defensive abilities: 
Chen, Dazzle, Io, Oracle, 
Omniknight, Witch Doctor, Winter Wyvern, 
Abaddon, etc.
Dark Willow
* Heroes with high magical or pure damage will bypass Bulwark: 
Timbersaw, 
Dark Willow, 
Enigma, Invoker, Pugna, Skywrath Mage, Tinker, 
Zeus, Oracle.
Dark Willow
* Heroes with powerful rooting abilities will disable most of Pangolier's skills, a bonus point if it pierces spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, 
Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren
Dark Willow
* Primal Beast really suffers against supports he cannot bully in the lane: this includes Dazzle, Shadow Demon and Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Nature's Prophet is extremely easy to gank with Relocate while he's split pushing.
* Tether on a friendly unit can destroy Nature Prophet's trees should he surround himself with 
Sprout as a defense.
Dark Willow
* 
Gust can hit Dark Willow beyond a defensive Bramble Maze, and before she gets close enough to hit Drow Ranger with Bedlam.
* Drow Ranger's long range allows her to hit Dark Willow's team without venturing into her Bramble Maze.
Io
* Drow Ranger's lack of escape abilities makes her an easy target for Relocate ganks.
Dark Willow
* 
Rot and 
Meat Hook hits Dark Willow even when she uses Shadow Realm.
* 
Flesh Heap reduces Dark Willow's magic burst damage.
Io
* Tether and Overcharge makes it much harder for Pudge to kill a target with Meat Hook, and Relocate can save the Io's ally while 
Dismember is being channeled.
Io
* 
Thirst allows Bloodseeker to see where Io relocated to, should either Io or the tethered hero have low health.
* 
Rupture forces Io to stay in place, preventing it from using the Tether bonus movement speed to escape.
Dark Willow
* Bramble Maze greatly hinders Bloodseeker's ability to run around in teamfights and pick off dying allies.
* Shadow Realm prevents Bloodseeker from attacking dark Willow, allowing her to safely teleport away.
Io
* 
Duel is very effective against Io due to its low health and armor.
Io
* Tethered heroes are much harder for Legion Commander to kill in Duels.
* Relocate can cancel Duels and save allies.
Io
* 
Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* 
Greater Bash and 
Nether Strike is devastating due to Io's low armor, and can even knock it away from tethered target.
Dark Willow
* Bramble Maze stops Charge of Darkness in its tracks. Its very long duration means it can be used as an obstacle to block off an incoming Spirit Break during teamfights.
* Shadow Realm and Bedlam can be activated when Dark Willow sees Charge of Darkness coming, preventing Spirit Breaker from using Nether Strike after the initial stun.
Io
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
Ice Path can be used to cancel both, Tether and Relocate.
Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for 
Ice Path and 
Macropyre.
Ice Path can be used to cancel both, Tether and Relocate.
Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for 
Ice Path and 
Macropyre.
*
* Jakiro commonly buys
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
*
* Jakiro commonly buys
Dark Willow
* Jakiro's area of effect abilities can hit Dark Willow even while she is hidden during the
Shadow Realm.
Cursed Crown, Jakiro's Ice Path stun lasts slightly longer then Cursed Crown.
* Waiting about 2 seconds after Dark Willow casts Shadow Realm to cast Ice Path will stun her while her Shadow Realm is at it's maximum damage.
* Jakiro can stun Dark Willow when there is about 1 second left on