Io
* Disruptor can always Glimpse back Io or his target after he 
Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that 
Tethered away in the fog of war.
Additional:
* 
Glimpse directly negates Relocate.
* 
Kinetic Field prevents Io from escaping with Tether.
* 
Static Storm can silence and damage both, Io and it's tethered target. And it can also mute both, Io and it's tethered target when upgraded with 
Aghanim's Scepter.
Primal Beast
* Glimpse can prevent Primal Beast from initiating for most of the game with Onslaught.
* While Static Storm is not much of a threat in terms of damage, it does prevent Primal Beast from casting any spells for a long period of time if also trapped in Kinetic Field.
* Overall, Disruptor forces Primal Beast to buy a 
Black King Bar much earlier than he might like but becomes a major threat to Disruptor once he does.
Io
* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.
Additional:
* Grimstroke can catch Io and his Tethered ally easily with 
Soulbind as Io has a tendency to Tether himself with an ally frequently, which also makes them easier targets for Soulbind.
* Io is highly vulnerable to disables. Hence, Grimstroke's 
Phantom's Embrace is a great ability to hinder Io's potential.
Primal Beast
* Soulbind prevents Primal Beast from being able to use Onslaught or his abilities to great effect for a lengthy amount of time.
* Phantom's Embrace is very difficult for Primal Beast to remove due to his slow attack speed and Trample preventing him from attacking.
Io
* 
Cold Embrace can render the extra attack speed from 
Overcharge meaningless.
* 
Splinter Blast and 
Winter's Curse are very affective against Io, as it has to stay close to his Tethered target.
Primal Beast
* Supports who can slow him to the point Trample does very little damage in the lane are also not fun: 
Lich, 
Ogre Magi, 
Winter Wyvern.
Io
* Lich's 
Chain Frost forces Io to either give up providing buff to his ally with Tether or suffer devastating damage with his Tethered ally.
* Lich can easily use 
Sinister Gaze to disable Io from getting away with Tether or Relocate.
Primal Beast
* Supports who can slow him to the point Trample does very little damage in the lane are also not fun: Lich, Ogre Magi, Winter Wyvern.
Io
* Fireblast is a good tool to interrupt Io during its escapes through Tether.
* Ignite can be one of the few spells with enough total damage to out-trade the sustained healing Io provides for its fellow laner.
* However, picking other supports that focus less on the laning phase is generally a better choice against Io.
Primal Beast
* Supports who can slow him to the point Trample does very little damage in the lane are also not fun: Lich, Ogre Magi, Winter Wyvern.
Io
* 
Poison Touch allows Dazzle to harass both, Io and it's tethered target on lane. 
Aghanim's Shard upgraded Poison Touch can also hex both, Io and it's tethered target, preventing them from escaping with Relocate, and also disarming them, silencing them, muting them and rendering them helpless against Dazzle and his allies.
* Io's damage output is one of the weakest, therefore Dazzle will have plenty of time to save an ally with 
Shallow Grave from gank by Io and it's tethered target.
* 
Shadow Wave will always hit both, Io and it's tethered target if they are near the ally Dazzle uses Shadow Wave on, while healing Dazzle's allies near them. Aghanim's Scepter upgraded Shadow Wave can bounce on both, Io and it's tethered target, causing them both to take damage and to be attacked by Dazzle. And unlike Io who doesn't get healed while using Tether, Shadow Wave will always heal Dazzle no matter on which of his allies he uses it on.
* 
Bad Juju will cause both, Io and it's tethered target to lose armor every time Dazzle casts a spell while strengthening armor of Dazzle's allies.
Additional:
* Poison Touch allows Dazzle to harass both, Io and it's Tethered target on lane. Aghanim's Shard upgraded Poison Touch can also hex both, Io and it's Tethered target, preventing them from escaping with Relocate, and also disarming them, silencing them, muting them and rendering them helpless against Dazzle and his allies.
* Io's damage output is one of the weakest, therefore Dazzle will have plenty of time to save an ally with Shallow Grave from gank by Io and it's Tethered target.
* Shadow Wave will always hit both, Io and it's Tethered target if they are near the ally Dazzle uses Shadow Wave on, while healing Dazzle's allies near them. Aghanim's Scepter upgraded Shadow Wave allows Dazzle Shadow Wave directly on Io and it's Tethered target which can also bounce on both, Io and it's tethered target, causing them both to take damage and to be attacked by Dazzle. And unlike Io who doesn't get healed while using Tether, Shadow Wave will always heal Dazzle no matter on which of his allies he uses it on.
* Bad Juju will cause both, Io and it's tethered target to lose armor every time Dazzle casts a spell while strengthening armor of Dazzle's allies.
Primal Beast
* Primal Beast really suffers against supports he cannot bully in the lane: this includes 
Dazzle, 
Shadow Demon and 
Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.
Io
* Heroes whose abilities can affect multiple enemies at once: 
Dawnbreaker, 
Ember Spirit, 
Lina, 
Luna, 
Jakiro, 
Leshrac, 
Invoker, 
Muerta, Dazzle.
Primal Beast
* Invoker's numerous area-of-effect abilities can interrupt Primal Beast, especially while he is in the middle of a team fight, where Primal Beast thrives. (
Tornado, 
Cold Snap, and 
Ice Wall all help to disable Primal Beast and control him from a distance.
* 
E.M.P. disintegrates Primal Beast's low mana pool.
* However, Invoker is quite a slow-paced hero and not particularly known for being survivable against a rampaging Primal Beast with Black King Bar.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: 
Beastmaster, 
Broodmother, 
Chaos Knight, 
Lycan, 
Naga Siren, 
Nature's Prophet, 
Phantom Lancer, 
Shadow Shaman, 
Terrorblade, 
Visage, 
Warlock, 
Wraith King.
Primal Beast
* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, 
Lion, 
Nyx Assassin.
Io
* Squishy heroes (
Io, 
Crystal Maiden, Lina...), as Earth Spirit can deal tons of damage with Magnetize.
Primal Beast
* Any ganking heavy support can be a big problem for Primal Beast, such as: 
Earth Spirit, 
Grimstroke before he has a Black King Bar.
Io
* Heroes with either magical, physical or pure damage burst: 
Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, 
Phantom Assassin, 
Skywrath Mage, 
Tinker, 
Ursa, 
Void Spirit.
Primal Beast
* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.
Primal Beast
* 
Borrowed Time allows him to both exit his stuns prematurely and turn Trample into healing for himself. His Aghanim Scepter only prevents the automation of the spell, Abaddon himself can still manually activate it.
* 
Aphotic Shield will immediately debuff any stuns Primal Beast has put on allies but won't stop him from being stunned if casted on Abaddon.
Primal Beast
* Oracle can negate and shut down Primal Beast simply with Fate's Edict, especially in the early game, as a majority of his damage-dealing spells are magic.
* Oracle can interrupt Primal Beast's 
Onslaught charge with a well-timed Fortune's End.
* Primal Beast's lethal burst damage combos can be further stalled with False Promise; combined with Fate's Edict and regen from Purifying Flames, Oracle can even completely negate Primal Beast's offense.
Additional:
* 
Fate's Edict completely negates all of Primal Beast's major damage-dealing spells in the early game and can render Primal Beast useless when cast on a target he is focusing, or in Oracle's defense against Primal Beast himself.
* 
Fortune's End keeps Primal Beast in place, especially while trampling or in the middle of an Onslaught charge.
* 
False Promise can interrupt Primal Beast's abilities, as well as further delay Primal Beast from dealing lethal burst damage. In combination with Fortune's End, Oracle can potentially save an ally from Primal Beast's spell combos.
Io
* 
Living Armor and 
Leech Seed can be used to save a hero from a Relocate gank.
* 
Overgrowth can be used to cancel escape attempts with Relocate.
* Once Treant Protector buys Aghanim's Scepter, he will gain access to 
Eyes in the Forest, that will allow him to enchant a tree which will grant him unobstructed vision in that location, allowing him to keep his allies alerted on Io and his Tethered's attempts to gank them, and which can also allow Overgrowth to damage them and root them if they are within a 800 radius of an tree affected by Eyes in the Forest.
Primal Beast
* 
Malefice will prevent Primal Beast from doing anything for a long duration even in the early game when at his strongest.
* 
Midnight Pulse will scale with his max health so will do a ton of damage combined with any generic stun or Enigma's own abilities.
* Primal Beast relies completely on mobility to do damage, 
Black Hole makes sure he cannot use any abilities or threaten heroes he is typically good against.
Io
* 
Strafe, 
Tar Bomb and 
Burning Barrage from Aghanim's Shard allow Clinkz to quickly kill Io due to its low armor.
* Clinkz iz a hero that very often goes for 
Orchid Malevolence, and its upgrade 
Bloodthorn. Alternatively, Clinkz also loves to buy 
Gleipnir. And if Clinkz has both of them, he will be able to root and silence Io and prevent him from escaping with either Tether or Relocate.
Primal Beast
* 
Power Cogs keeps Primal Beast pinned down, preventing him from doing damage with Trample. Primal Beast's slow attack speed makes it hard for him to break the cogs and get away. In addition, Power Cogs' knockback is forced movement and thus will intercept Primal Beast's Onslaught if placed well.
* 
Battery Assault on a lone Primal Beast in the early game effectively keeps him from winding up Onslaught or basic attacking.
* 
Rocket Flare and 
Jetpack (from purchasing Aghanim's Shard) give Clockwerk many options to scout for Primal Beast, whose kit benefits greatly from ambushing.
Primal Beast
* 
Shukuchi allows Weaver to have faster movement speed and can outrun Primal Beast in most instances, such as while he is trampling.
* Trample disarms Primal Beast, so casting 
The Swarm can make him vulnerable to ranged attacks. Primal Beast also has an innately slow attack speed and will take a long time destroying the bugs.
* 
Time Lapse allows Weaver to negate and heal burst damage, which Primal Beast is reliant on.
Primal Beast
* The ensnare from melee 
Berserker's Rage can prevent Primal Beast from dealing further Trample damage and can allow Troll Warlord to relentlessly build 
Fervor on him.
* 
Whirling Axes (Ranged) can slow down Primal Beast while trampling and allow Troll Warlord to better control him from range.
* 
Whirling Axes (Melee) can blind Primal Beast if he attempts to auto-attack Troll Warlord after a fully charged Uproar.
* 
Battle Trance will make Primal Beast a sitting duck should he be rooted and attacked to death.
Io
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* 
Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys 
Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and 
Macropyre.
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Primal Beast
* 
Time Walk makes it impossible for Primal Beast to stay on top of Faceless Void with his abilities and allows him to heal burst damage dealt to him.
* Once Faceless Void has an Aghanim's Shard, Onslaught can be easily escaped. He could also choose to get a lower cooldown on Time Walk, making it even harder for Primal Beast to catch him in fights or stop his initiations.
* 
Time Dilation will make Primal Beast useless for an extended time after casting his abilities if he does not have a dispel.
* 
Chronosphere has many uses such as stopping Primal Beast from casting abilities on him or allies or even on a teammate, since Primal Beast has no way to assist allies trapped within the sphere.
Io
* 
Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.
Io
* Batrider's 
Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying 
Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Additional:
* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Primal Beast
* Heroes who can do scaling health damage to Primal Beast are very threatening for the hero. Such as: 
Phoenix, Tinker etc.
Primal Beast
* Heroes with unorthodox escapes will struggle against Primal Beast, such as Nature's Prophet, Tinker, and 
Templar Assassin.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Primal Beast
* Primal Beast is mostly played in the offlane role, so picking a carry who can escape from him is essential. Heroes such as 
Troll Warlord, 
Lone Druid and 
Outworld Destroyer, or generally any carry with a stun, slow or ability to fight back will stop him from having the good start he needs.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:Crystal Maiden, 
Pugna, Skywrath Mage, Io, 
Witch Doctor, etc.
Primal Beast
* Primal Beast is mostly played in the offlane role, so picking a carry who can escape from him is essential. Heroes such as Troll Warlord, Lone Druid and Outworld Destroyer, or generally any carry with a stun, slow or ability to fight back will stop him from having the good start he needs.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes that are hard to gank: 
Axe, 
Death Prophet, Phantom Lancer, 
Slark, 
Centaur Warrunner, 
Bristleback, 
Medusa, 
Mars.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Primal Beast
* Primal Beast really suffers against supports he cannot bully in the lane: this includes Dazzle, Shadow Demon and Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Primal Beast
* Primal Beast really suffers against supports he cannot bully in the lane: this includes Dazzle, Shadow Demon and Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.
Io
* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker, Muerta, Dazzle.
Io
* Heroes that can easily bypass Io's allies to get to Io: 
Riki, 
Tusk, 
Clinkz, 
Sniper, Slark, Phantom Assassin, Void Spirit, 
Storm Spirit, Ember Spirit, Earth Spirit, 
Spirit Breaker, 
Lifestealer.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Primal Beast
* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Io
* Heroes with the ability to heal allies will not be able to heal heroes affected by 
Doom: 
Chen, Dazzle, Io, 
Oracle, 
Omniknight, Witch Doctor, Winter Wyvern, 
Abaddon, etc.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Io is a hero who needs to be close to it's tethered target to make it effective, and that's where Leshrac gets the advantage thanks to many of his area-of-effect abilities.
* 
Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* 
Diabolic Edict and 
Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to both, Io and its tethered target.
Additional:
* Lightning Storm will usually hit both Io and his Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.
Primal Beast
* Heroes who rely on burst damage with magical damage will struggle to kill Primal Beast: Spirit Breaker, 
Gyrocopter, Leshrac
Io
* 
Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* 
Greater Bash and 
Nether Strike is devastating due to Io's low armor, and can even knock it away from his Tethered target.
Primal Beast
* Heroes who rely on burst damage with magical damage will struggle to kill Primal Beast: Spirit Breaker, Gyrocopter, Leshrac
Io
* 
Homing Missile can be used to cancel escape attempts with Relocate.
* 
Flak Cannon allows Gyrocopter to attack both, Io and his Tethered target, especially when upgraded with Aghanim's Scepter.
* 
Rocket Barrage and 
Call Down allow Gyrocopter to deal serious damage to both Io and his Tethered target.
Additional:
* Homing Missile can be used to cancel escape attempts with Relocate.
* Flak Cannon allows Gyrocopter to attack both, Io and his Tethered target, especially when upgraded with Aghanim's Scepter.
* Rocket Barrage and Call Down allow Gyrocopter to deal serious damage to both Io and his Tethered target.
Primal Beast
* Heroes who rely on burst damage with magical damage will struggle to kill Primal Beast: Spirit Breaker, Gyrocopter, Leshrac
Io
* 
Ensnare and 
Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* 
Rip Tide combined with illusions from 
Mirror Image often finish off Io before he can save himself with Tether or Relocate.
* 
Spirits's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys Aghanim's Scepter, she can gain access to 
Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's Flaming Lasso.
* Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his Tethered targed try to gank.
Additional:
* Ensnare and Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
* Rip Tide combined with illusions from Mirror Image often finish off Io before he can save himself.
* Spirit's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from Mirror Image.
* Once Naga Siren buys Aghanim's Scepter, she can gain access to Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with Ensnare, similarly to Batrider's Flaming Lasso.
* Aghanim's Shard upgraded Song of the Siren can also heal the hero Io and his tethered targed try to gank.
Primal Beast
* Illusion heroes will struggle against Primal Beast's area damage capability, such as Chaos Knight, Naga Siren, Terrorblade.
Io
* Drow Ranger's lack of escape abilities makes her an easy target for Relocate ganks.
Primal Beast
* Heroes who have low or high armor but very high health will be difficult for drow to burst down quickly: 
Primal Beast, Axe, Centaur Warrunner.
Io
* Heroes with abilities that can save teammates are also effective such as Shadow Demon, Dazzle, Oracle, Bane, Pugna, Tusk, Winter Wyvern, Io, 
Underlord, 
Treant Protector and 
Keeper of the Light.
Primal Beast
* Primal Beast can use Uproar to tank a portion of 
Omnislash, making him much more likely to survive it. Primal Beast can also charge away from Omnislash using Onslaught as the spell ends.
* 
Blade Fury will never do more damage than Uproar once the stacks are activated.
* Primal Beast is very commonly buying items that are good against Juggernaut, such as 
Ethereal Blade and 
Heart of Tarrasque.
* Primal Beast has one of the few ultimates that can prevent Juggernaut from spinning away with a teleport.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Nature's Prophet is extremely easy to gank with Relocate while he's split pushing.
* Tether on a friendly unit can destroy Nature Prophet's trees should he surround himself with 
Sprout as a defense.
Primal Beast
* Sprout gets destroyed by Trample and Onslaught.
Primal Beast
* Magnus is not tanky and struggles against burst damage, something Primal Beast excels at in the early-to-mid game. Primal Beast is also able to out-damage Magnus's 
Empower and can even contribute to his Uproar stacks.
* Using 
Skewer to drag Primal Beast while he is trampling will count as movement and will trigger a rapid number of slams, which could prove lethal to Magnus.
Primal Beast
* 
Dispersion reduces damage based on a percentage, which is very minimal against large amounts of small instances of damage such as Trample. It reduces each tick by about 14 at the maximum level, which is very small.
* 
Desolate is never a threat to Primal Beast due to his large health pool and Uproar is still out-damaging the ability.
* Onslaught can allow Primal Beast to chase Spectre fleeing with 
Spectral Dagger, as both skills phase through trees and terrain.
* Primal Beast can also dispel Spectral Dagger's slow with his left level 15 talent, making it completely useless against him.
* Primal Beast excels at early aggression, pushing weak carries out of lane and farming areas he wants to control. Overall just not a pleasant matchup for Spectre.
* Should Primal Beast buy an Aghanim's Scepter he can also break both passive abilities.
Primal Beast
* Primal Beast has multiple ways to cancel 
Life Drain very quickly.
* Pugna has a very low strength gain and as a support does not have much gold to buy health items, making him vulnerable to Primal Beast's onslaught of magical damage.
* Ironically, 
Decrepify actually just increases Primal Beast's damage on the targeted ally if Trample is activated. However, it can be used to slow him down and prevent any further Trample damage.
Io
* Tether and Overcharge makes it much harder for Pudge to kill a target with 
Meat Hook, and Relocate can save the Io's ally while 
Dismember is being channeled.
Primal Beast
* Onslaught prevents all of Razor's abilities from being effective against him, especially in the laning stage.
Io
* Tether helps Io escape from Earthbind even if Meepo has Blink Dagger.
* Io's Spirits can pressure Meepo while laning and will usually hit at least one of his clones.
Primal Beast
* Any hero who lanes very poorly will struggle with Primal Beast's potential snowball in the very early levels, like Keeper of the Light, Luna, Templar Assassin...
Io
* 
Take Aim and 
Assassinate allow Sniper to reach Io even if it stays in the backline.
Io
* Heroes with high mobility can approach Sniper: 
Anti-Mage, Earth Spirit, Io, Nature's Prophet, 
Pangolier, 
Puck, 
Queen of Pain and most notably Riki.
Primal Beast
* Primal Beast is one of Sniper's greatest counters, as he has no real means of escape and is very squishy, especially in the early game. Sniper's potshots and 
Shrapnel can contribute to Primal Beast's Uproar and further make him tankier than he already is. Onslaught allows him to close the gap on Sniper at his own volition, and Trample can deal serious damage to his meager health pool.
Primal Beast
* Any hero with low mobility and max healthsuch as 
Silencer, Crystal Maiden etc.
Primal Beast
* Any hero who lanes very poorly will struggle with Primal Beast's potential snowball in the very early levels, like Keeper of the Light, Luna, Templar Assassin...
Primal Beast
* Any hero with low mobility and max healthsuch as Silencer, Crystal Maiden etc.
Primal Beast
* Heroes who cannot escape from Trample early might be easy first blood. Heroes like Witch Doctor and Omniknight should play very cautiously alone...
Primal Beast
* Heroes who cannot escape from Trample early might be easy first blood. Heroes like Witch Doctor and Omniknight should play very cautiously alone...
Io
* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker, Muerta, Dazzle.
Primal Beast
* 
Pierce the Veil does not prevent Primal Beast from using any of his spells to their fullest and is one of the few heroes that can disable her during her ultimate and a common Black King Bar purchase. She will also likely be fatal to herself if Primal Beast has a 
Blade Mail active.
* 
Gunslinger will be disabled if Primal Beast buys an Aghanim's Scepter.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Primal Beast
* 
Dark Pact, 
Shadow Dance and 
Depth Shroud will do nothing against Onslaught and Trample, as they are both ground area-of-effect spells.
* Primal Beast has a gigantic hitbox, which could be difficult for Slark to escape with 
Pounce should Primal Beast choose to block him. Pounce also does not completely prevent Primal Beast from trampling offensively, as he still has some room to move.
* Primal Beast has a huge health pool making it difficult to shed it with 
Essence Shift and may allow Primal Beast to build Uproar stacks against him very rapidly.
* If Primal Beast buys an Aghanim's Scepter he can also break Essence Shift from working on attacks which is a big part of Slark's damage output.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Primal Beast
* While Broodmother can hide in the trees with 
Spin Web, Primal Beast's ability to trample trees down can give him an edge in catching her.
* 
Insatiable Hunger will not do much vs Primal Beast's onslaught of disables.
* While 
Silken Bola can slow Primal Beast down, it's not enough to stop Trample from doing more damage than Broodmother can do back.
* 
Spawn Spiderlings will be destroyed by Onslaught and Trample very easily.
Io
* Terrorblade can easily take advantage of Io's weak durability with 
Reflection and 
Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from 
Conjure Image and 
Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with 
Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and his Tethered target to escape with Relocate besides 
Terror Wave from Aghanim's Scepter.
Additional:
* Terrorblade can easily take advantage of Io's weak durability with Reflection and Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from Conjure Image and Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and it's Tethered target to escape with Relocate besides Terror Wave from Aghanim's Scepter.
Primal Beast
* Terrorblade has no stun and is vulnerable to Primal Beast's spell comboes due to his low health points in the laning stage and mid game.
* Reflection can be dispelled using Primal Beast's level 15 left talent.
* Sunder is the only real threat Terrorblade has against Primal Beast but he may die before he can even use it.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Primal Beast
* Illusion heroes will struggle against Primal Beast's area damage capability, such as Chaos Knight, Naga Siren, Terrorblade.
Io
* 
Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's Diabolic Edict, Lightning Storm and Pulse Nova abilities. Luna's 
Moon Glaives and 
Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Additional:
* Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse can be used to cancel both, Tether and Relocate.
* Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Primal Beast
* Primal Beast has a massive healthpool making it very difficult to get through it with a nuke such as Eclipse or Lucent Beam.
* Primal Beast is faster than Luna, as one of her main ways to escape danger, is very problematic for her in the laning stage especially.
* His ultimate goes through debuff immunity, making Luna's Black King Bar less effective.
* Primal Beast commonly buys Blade Mail which is a big problem for a single target bursting hero like Luna.
Primal Beast
* Primal Beast is disarmed during Trample so will be unable to destroy a 
Supernova no matter how close it is to him.
* The same ability can also be used to save allies with the help of an Aghanim's Scepter.
* 
Sun Ray will do thousands of damage to Primal Beast if surviving a full channel time due to his high health scaling for the ability.
* 
Icarus Dive is a fantastic way to escape Primal Beast after he has used Onslaught.
* Phoenix has a naturally very high health pool making it hard for Primal Beast to deal with him with his magical damage.
Io
* Phoenix's limit AoE, damage-over-time abilities give Io plenty of time to save allies with Relocate.
Io
* Ice Blast prevents Io from healing an ally with Tether and prevents healing from Overcharge
* Io is a common 
Mekansm builder which is useless if he is affected by Ice Blast.
Additional:
* 
Ice Blast prevents Io from healing the target.
* Ancient Apparition can easily harass Io on lane with 
Chilling Touch due to it's high range and damage. This can get even worse if Ancient Apparition buys Aghanim's Scepter and combines it with items that can give him bonus attack damage and attack speed.
* Chilling Touch combined with 
Ice Vortex makes it nearly impossible for Io to escape from 
Cold Feet. Ice Vortex can also make Io and it's tethered target more vulnerable to Ancient Apparition and his allies's magical damage.
Primal Beast
* Since Primal Beast is highly mobile with Onslaught alone, he will be difficult to catch with both Cold Feet and Ice Blast.
* Ice Blast is less effective due to Primal Beast's massive health pool and resistance to taking damage.
* While Chilling Touch can be used to slow Primal Beast briefly, it is not enough to beat him back, and can also contribute to his Uproar stacks.
* Primal Beast has a dispel talent at level 15 that will remove Cold Feet immediately when Uproar is used.
Io
* 
Phantom Strike allows Phantom Assassin jump directly to Io.
* 
Coup de Grace can make a short work of Io's low health and armor.
Primal Beast
* Phantom Assassin is known to be weak against bursts of magical damage, something Primal Beast excels at from the beginning of the game. He can use this to his advantage by constantly hunting Phantom Assassin down, especially if she is left alone to farm.
* Primal Beast is a good carrier of Ethereal Blade, 
Vanguard and 
Shiva's Guard all of which are very good against Coup de Grace and Phantom Strike.
* Even though Primal Beast does a lot of physical damage early on, later once 
Blur becomes more potent, she may find herself being overwhelmed by Trample and Onslaught instead.
* Primal Beast's ultimate goes through spell immunity and his level 25 talent makes it even more devistating against Phantom Assassin.
* Primal Beast can dispel 
Stifling Dagger and any attack modifers it applies with his left level 15 talent.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Primal Beast
* Special mention to Lifestealer who can use 
Rage to prevent Trample damage, but Primal Beast's ultimate can still be casted during the spell.
Io
* 
Duel is very effective against Io due to its low health and armor.
Io
* Tethered heroes are much harder for Legion Commander to kill in Duels.
* Relocate can cancel Duels and save allies.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Primal Beast
* Long lockdown is a great way to deal with Axe to prevent Berserker's Call from being used, heroes such as 
Legion Commander, Beastmaster and Primal Beast are good examples of this.
Additional:
* 
Berserker's Call will be a stun for Primal Beast and not much else due to Trample making him unable to attack.
* 
Battle Hunger is neglitable because Primal Beast has a much bigger health than Axe, so he does not need to fear being slowed, or his other abilities including 
Counter Helix or even a Blade Mail.
* Getting Primal Beast low enough to use a successful 
Culling Blade can be very difficult due to his massive health advantage over most heroes.
* Not ability related but Primal Beast does not need to fear Axe in lane, as Trample, combined with Uproar and Onslaught will do a ton of damage even if Axe has a Vanguard.
Primal Beast
* 
Pit of Malice is very good at preventing Primal Beast from entering the fight and stopping Trample damage at all stages of the game.
Io
* Io can escape from Pit of Malice with Tether or Relocate.
* Relocate can counter Dark Rift's split pushing.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Primal Beast
* Hard carries who just want to farm and be left alone will not appreciate Primal Beast, heroes such as Medusa, 
Drow Ranger...
Io
*
Thirst allows Bloodseeker to see where Io relocated to, should either Io or the tethered hero have low health.
Rupture forces Io to stay in place, preventing it from using the Tether bonus movement speed to escape.
*
Primal Beast
* Primal Beast's abilities require movement to deal damage, making
Rupture potentially deadly and debilitating. Furthermore, its initial damage based on the target's current health is devastating to a full-health Primal Beast with his high strength gain and thus high HP.
Blood Rite's powerful silence without items to counter it.
* Due to his reliance on spells, Primal Beast is vulnerable to