Jakiro
* Kraken Shell dispels 
Dual Breath, 
Ice Path, 
Liquid Frost, 
Liquid Fire and even 
Macropyre's Burn.
* It also completely negates the damage from Liquid Fire and Ice path, while heavily reducing the damage from all of his other abilities
* Jakiro is a naturally slow hero, Gush will allow you to easily catch him, while also reducing his Armor
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: 
Tidehunter, 
Bristleback, 
Slardar.
Jakiro
* Heroes with good counter-push abilities to clear creep waves can hinder Jakiro's early pushing ability: 
Death Prophet, 
Sniper, 
Tinker, 
Windranger.
Medusa
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.
Additional:
* Medusa is a fairly immobile hero that deals damage around her with 
Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her 
Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Jakiro
* Heroes with good mobility to avoid Jakiro's abilities and with good chase to punish Jakiro from pushing a tower: 
Bloodseeker, 
Ember Spirit, 
Juggernaut, 
Phantom Assassin, 
Weaver.
Medusa
* Heroes that build 
Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: 
Riki, 
Naga Siren, 
Terrorblade, Juggernaut, 
Spectre, 
Slark.
Jakiro
* 
Fate's Edict allows Oracle to make allies spell immune, allowing him to save allies from Jakiro's spells.
* Fate's Edict can be cast onto Jakiro to disarm him and prevent him from pushing with his Liquid Fire.
* 
False Promise allows Oracle to free allies from Jakiro's Ice Path.
Medusa
* 
Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* 
Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.
Jakiro
* 
Astral Imprisonment can be used to protect allies from Jakiro's various abilities, It can also be cast on Jakiro to break his combos (Macropyre into Ice path into Dual Breath), while at the same time, stealing his much needed mana.
* 
Aghanim's Shard upgraded Astral Imprisonment allows Outworld Destroyer and his allies to move while imprisoned, which allows them to leave the area of Jakiro's abilities.
* As Outworld Destroyer is prone to buying 
Meteor Hammer, he can combine it with Astral Imprisonment and 
Arcane Orb's high pure damage that can quickly decimate Jakiro, And unlike most heroes, Outworld doesn't particularly care who he targets.
* Outworld is also a common Black King's Bar carrier, and Jakiro's only tool to counter it is the 
Aghanim's Scepter upgraded Macropyre
Medusa
* E.M.P. allows Invoker to burn Medusa's mana to weaken 
Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* 
E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* 
Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* 
Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.
Medusa
* Ursa's status resistance from 
Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with 
Fury Swipes easily against her Mana Shield in a prolonged team match.
Additional:
* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Medusa
* He can use either his own or his double's 
Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + 
Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double 
Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.
Jakiro
* 
Ancient Seal can silence Jakiro and make him vulnerable to magical spells up to 6 seconds.
* Skywrath Mage can usually burst down Jakiro with his high damage magical spells.
Jakiro
* 
Fade Bolt can hinder Jakiro's early pushing power by clearing creep waves.
* All of Jakiro's spells are great for Rubick to 
Spell Steal.
* Ice Path is a great spell for Rubick so steal, since Rubick has no cast time on stolen abilities, making Rubick's version of Ice Path much more reliable than Jakiro's.
* Macropyre is a great way for Rubick to farm.
Additional:
* One of Jakiro's weakness is his long cast animation, which gives enemy team extra time window to react. Rubick uses his fixed 0.15 second cast time for all Jakiro's stolen abilities, making the spells much easier to target.
* Dual Breath is a solid damage-over-time that is good for farming and helps with ganking.
* Ice Path is the go-to spell for Rubick to steal in teamfights - a sudden long range 2.5 second area stun is of no joke, especially if being casted out of vision. The control time is extended combined with 
Telekinesis.
* Macropyre is a solid damage source (an area to avoid at least) for Rubick's side, and the damage benefits from 
Arcane Supremacy, even further with Aghanim's Scepter.
* It is not uncommon that the enemy team mistakenly treated the Macropyre ground effect as that of Jakiro's, and has already taken a lot of damage before they noticed their significant HP loss.
* Combined with Rubick's Level 15 talent (-25% Stolen Spells Cooldown, as of 7.31c), Macropyre can be used to clear creep waves and camps with ease, increasing his farming progress if a fight is not imminent.
Medusa
* With 
Static Link, Razor can effectively make Medusa useless in teamfights by reducing her main damage output. It can, however, be blocked by a 
Linken's Sphere.
* 
Plasma Field allows Razor to get on top of Medusa, slowing her already slow movement speed to a mere crawl.
* 
Eye of the Storm capitilizes on Medusa's low armor and causes her to be very vulnerable, even through Mana Shield.
Jakiro
* Heroes with long cast animations can be continuously interrupted by Battery Assault: 
Centaur Warrunner, 
Jakiro, 
Leshrac, Naga Siren, 
Underlord.
Additional:
* 
Battery Assault prevents Jakiro from casting spells as all his spells have very long cast times.
* Jakiro is also an easy target for Clockwerk's Hookshot + Power Cogs combo, as he has little mobility and no escape without items.
* Alternatively, if the enemy Clockwerk traps one of his own allies or Jakiro's allies in the cogs, it gives Jakiro an ideal setup to punish Clockwerk and his ally or to save Jakiro's ally, respectively.
Jakiro
* Macropyre's frequent damage ticks causes Bristleback to activate repeatedly, resulting in free damage as long as Bristleback faces away from Jakiro.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Jakiro
* While Jakiro's damage is going to be little more then average against him due to his 
Bristleback. His large quantity of stuns can prevent Bristleback from getting his much needed 
Warpath stacks, while also giving his allies a chance to counter his high defense.
* Dual Breath and Liquid Frost both reduce Movement Speed, removing one of Bristlebacks greatest strengths.
* Liquid Fire reduces Bristlebacks Attack Speed, making it harder for him to burst down a hero with Warpath.
* However Bristleback can generally catch and kill a lone Jakiro. And Jakiro is only effective in a group.
Medusa
* Heroes who take a long time to become strong are in for a rough mid game, such as 
Outworld Destroyer, 
Magnus, 
Medusa, and 
Anti-Mage.
Jakiro
* Heroes with good counter-push abilities to clear creep waves can hinder Jakiro's early pushing ability: Death Prophet, Sniper, Tinker, Windranger.
Jakiro
* Heroes with good mobility to avoid Jakiro's abilities and with good chase to punish Jakiro from pushing a tower: Bloodseeker, Ember Spirit, Juggernaut, Phantom Assassin, Weaver.
Jakiro
* Heroes with no mobility will take some good damage from Sand King's spells: 
Dragon Knight, Jakiro, 
Pugna, 
Earthshaker.
Medusa
* 
Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's 
Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from 
Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Jakiro
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, 
Viper, 
Venomancer, 
Huskar, Ember Spirit, 
Dark Seer, 
Sand King, 
Doom, 
Dawnbreaker. However, this also means they are easily stunned.
Medusa
* Medusa is especially vulnerable to 
Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* 
Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.
Additional:
* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift particularly removes 1 intelligence point per hit, thus lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Jakiro
* Heroes with AoE abilities will hit Slark in Shadow Dance: 
Lina, Jakiro, Underlord, Leshrac, Dark Seer, Earthshaker, 
Timbersaw, 
Crystal Maiden.
Medusa
* 
Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* 
Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* 
Arena Of Blood blocks Medusa's attacks from outside the arena.
Medusa
* Medusa's Stone Gaze forces Mars to choose between getting petrified, or turning his vulnerable back on Medusa.
Jakiro
* Dual Breath, Liquid Fire, Liquid Frost from Aghanim's Shard and Macropyre allows Jakiro can clear Chen's creeps, and kill his allies before he uses Hand of God.
* Macropyre can quickly clear Chen's creeps and deal intense damage to his allies, Aghanim's Scepter upgraded Macropyre can also deal pure damage to Chen and his creeps and allies and pierce spell immunity.
Additional:
* Jakiro's damage over time force Chen to use 
Hand of God prematurely, potentially wasting chance to save his allies during teamfight.
* Dual Breath and Macropyre can be used to disrupt Chen's jungling work.
Medusa
* Medusa's Split Shot can easily kill Chen's creeps.
* Mystic Snake can quickly kill Chen's creeps and deal intense damage for every killed creep while also draining their mana with each bounce. Aghanim's Scepter upgraded Mystic Snake can also disable both, Chen and his creeps upon impact.
* Mana Shield will make it impossible for Chen to burst down Medusa.
* Stone Gaze can disable Chen from using Hand of God to save himself or his allies.
Jakiro
* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* Dual Breath and Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her 
Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use 
Eclipse by casting Ice Path on Luna.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.
Additional:
* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* Dual Breath and Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use Eclipse by casting Ice Path on Luna.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.
Medusa
* Should Luna choose to buy 
Manta Style, Medusa will be able to kill illusions from them with Split Shot and 
Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, which can cause Luna to struggle greatly in bursting down Medusa and force her to buy Diffusal Blade and it's upgrade 
Disperser.
* Even with 
Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Jakiro
* Most of the of Jakiro's damage-over-time abilities put 
Blink Dagger on cooldown, potentially forcing Enigma to prematurely activate Black King Bar.
* Jakiro's Dual Breath, Liquid Fire, Macropyre and Liquid Frost from Aghanim's Shard can take out Enigma's Eidolons, reduce Enigma's attack speed and put Enigma's Blink Dagger on cooldown.
* Jakiro can easily cancel 
Black Hole with Ice Path as Enigma is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Most of the of Jakiro's damage-over-time abilities put Enigma's Blink Dagger on cooldown, potentially forcing him to prematurely activate Black King Bar.
* Jakiro's Dual Breath, Liquid Fire, Macropyre and Liquid Frost from Aghanim's Shard can take out Enigma's Eidolons, reduce Enigma's attack speed and put Enigma's Blink Dagger on cooldown.
* Jakiro can easily cancel Black Hole with Ice Path as Enigma is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Medusa
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating and landing an effective Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult. Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.
Jakiro
* All of Jakiro's skills are Area of Effect, which can easily affect all Meepos in a targeted area.
Medusa
* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.
Jakiro
* Jakiro's abilities all deal magical damage over time, which allows him to attack Muerta even through 
Pierce the Veil.
* Dual Breath and Liquid Fire can be used to harass Muerta on lane.
* Ice Path can be used to stun Muerta when she uses Pierce the Veil, giving his allies time to escape or counter-initiate against Muerta.
* Aghanim's Scepter upgraded Macropyre can deal pure damage and pierce debuff immunity, rendering both, Pierce the Veil and Black King Bar useless.
* However, Jakiro is vulnerable to Muerta's 
The Calling as it can easily silence him due to his low mobility. In addition, Liquid Fire and Liquid Frost from Aghanim's Shard will not be able to be used on Muerta while Pierce the Veil is active unless she is near the enemy hero Jakiro targets with Liquid Fire and Liquid Frost or until Jakiro buys 
Revenant's Brooch.
Medusa
* Any long duration disables that can pierce through both, Pierce The Veil and Black King Bar are devastating against Muerta: 
Enigma's Black Hole, Dawnbreaker's 
Solar Guardian, 
Axe's 
Berserker's Call, Naga Siren's Aghanim's Scepter upgraded 
Ensnare and 
Reel In from Aghanim's Scepter, Jakiro's Aghanim's Scepter upgraded Macropyre, 
Bane's 
Fiend's Grip, 
Pudge's 
Dismember, 
Batrider's 
Flaming Lasso, 
Beastmaster's 
Primal Roar, 
Grimstroke's 
Soulbind, Medusa's Stone Gaze, Magnus's 
Reverse Polarity.
Jakiro
* Jakiro's abilities deal damage over time, which can disrupt Magnus's attempts to initiate with Blink Dagger and Reverse Polarity.
* Macropyre not only disables Blink Dagger for a considerable duration, but can also destroy Trees, revealing Magnus's cover and position.
Medusa
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: 
Sven, 
Omniknight, Enigma, 
Luna, Naga Siren, 
Mars, Jakiro, Venomancer, 
Elder Titan, 
Faceless Void, 
Rubick, 
Keeper of the Light, Pugna, 
Invoker, Spectre, 
Alchemist, 
Treant Protector, Lina, 
Oracle, 
Zeus, 
Shadow Shaman, 
Phoenix, 
Razor, Huskar, Batrider, 
Kunkka, Tidehunter, 
Wraith King, Sand King, Medusa, Dawnbreaker.
Jakiro
* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, 
Dazzle, 
Arc Warden, 
Lion, Huskar, Shadow Shaman, 
Visage, 
Undying, Jakiro.
Medusa
* If Medusa activates Stone Gaze before Spirit Breaker reaches her with Charge of Darkness, the charge will inevitably fail.
* Medusa has three ways to counter Spirit Breaker's Charge of Darkness: Stone Gaze can disable Spirit Breaker's Charge of Darkness if he faces Medusa directly. Aghanim's Scepter upgraded Mystic Snake can disable Spirit Breaker and cancel his Charge of Darkness if it hits him. And 
Cold Blooded provided by Aghanim's Shard that can cast a single-targeted Mystic Snake at Spirit Breaker if he uses Charge of Darkness on her.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation. And to make things worse, Spirit Breaker is not a common Diffusal Blade nor Disperser wielder to counter this problem at all.
* Overall, any attempt for Spirit Breaker to gank and kill Medusa will hurt him more than the other way around.
Jakiro
* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren 
Chaos Knight, 
Phantom Lancer, 
Broodmother, 
Nature's Prophet, 
Lycan, Wraith King, Visage.
Medusa
* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake
Jakiro
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys 
Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Medusa
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Jakiro
* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.
Medusa
* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Jakiro
* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of 
Song of the Siren.
* Naga Siren is not a hero that likes to go for Black King Bar, and that makes her very vulnerable to Jakiro's damage over time in every phase of the game.
Additional:
* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of Song of the Siren.
* Since Naga Siren is a hero who barely goes for Black King Bar, this can make her very vulnerable to Jakiro's damage over time in every phase of the game.
Medusa
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Additional:
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Jakiro
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's 
Light Strike Array, Broodmother's 
Spinner's Snare from Aghanim's Scepter, Elder Titan's 
Earth Splitter and 
Echo Stomp, Alchemist's 
Unstable Concoction and 
Acid Spray, 
Queen of Pain's 
Sonic Wave, Dark Seer's 
Wall of Replica and 
Vacuum, Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from Aghanim's Shard, Bloodseeker's 
Blood Rite, Enigma's Black Hole and 
Midnight Pulse, 
Shadow Fiend's 
Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, 
Ancient Apparition's 
Ice Blast, Sand King's 
Epicenter, 
Sand Storm and 
Burrowstrike, 
Gyrocopter's 
Call Down, Ember Spirit's 
Sleight of Fist, Death Prophet's 
Exorcism and 
Silence, 
Monkey King's 
Wukong's Command, Crystal Maiden's 
Freezing Field, 
Muerta's The Calling, Medusa's Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, 
Pangolier's 
Swashbuckle, Grimstroke's Soulbind, 
Ink Swell and 
Stroke of Fate, Earthshaker's 
Echo Slam and 
Fissure, 
Puck's 
Dream Coil and 
Waning Rift, 
Winter Wyvern's 
Winter's Curse, Magnus's Reverse Polarity.
Medusa
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.
Medusa
* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.
Medusa
* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.
Jakiro
* Batrider has poor survivablilty, relying on his mobility from Firefly to survive. Stunning him with Ice Path of Liquid Frost can easily spell his doom.
* Batrider tends to cast Flaming Lasso on the squishest or the tankiest hero. Which Jakiro is not squishy, nor his generally the tank of the team, Due to this, Jakiro can usually save allies with Ice Path and Liquid Frost, while also potentially removing an entire hero from play for a short period of time.
* Even if Batrider does cast Flaming Lasso on Jakiro, Batrider will generally drag Jakiro into a great setup for Ice Path and Macropyre.
Medusa
* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.
Jakiro
* Dual Breath and Liquid Fire reduces Tiny's already abysmal Attack Speed.
* If Tiny 
Tosses a hero onto Jakiro, he can react with Ice Path, and potentially Macropyre.
* Tiny's 
Avalanche is easily countered with Ice Path.
* As Tiny has a very high Health, Liquid Frost is particularly effective against him.
Jakiro
* Jakiro's skill arsenal can ruin Nature's Prophet's gameplay: Dual Breath and Liquid Fire can clear treants from 
Nature's Call while simultaneously slowing Nature's Prophet, Ice Path can disrupt Nature's Prophet's escaping attempt with 
Teleportation, and Macropyre can easily clear treants from Nature's Call.
* Jakiro is a common 
Hurricane Pike wielder, which allows him to escape from 
Sprout.
Additional:
* Jakiro's Macropyre can help him to escape from Sprout and quickly clears Treants.
* Jakiro can disrupt Nature's Prophet's escape attempt with Sprout and Teleportation by using Ice Path.
Medusa
* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to fight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalize on his commitment in a fight.
Jakiro
* Despite Jakiro's fragileness, he can easily harass Shadow Fiend with Dual Breath and Liquid Fire than Shadow Fiend can harass Jakiro with 
Shadowraze.
* Jakiro can easily cancel Requiem of Souls with Ice Path as Shadow Fiend is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Shadow Fiend from even trying to initiate with Requiem of Souls.
Additional:
* Despite Jakiro's fragileness, he can easily harass Shadow Fiend with Dual Breath and Liquid Fire than Shadow Fiend can harass Jakiro with Shadowraze.
* Jakiro can easily cancel Requiem of Souls with Ice Path as Shadow Fiend is a very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Shadow Fiend from even trying to initiate with Requiem of Souls.
Jakiro
* With his AoE damage, Jakiro can easily kill Chaos Knight's 
Phantasm illusions.
* Chaos Knight usually doesn't buy a Black King Bar, making him vulnerable to an Ice Path into Macropyre combination.
Additional:
* With his AoE damage, Jakiro can easily kill Chaos Knight's Phantasm illusions.
* Chaos Knight usually doesn't buy a Black King Bar, making him vulnerable to an Ice Path into Macropyre combination.
Jakiro
* With Dual Breath, Liquid Fire and Macropyre Jakiro can quickly remove all 
Living Armor from a target.
* Ice Path allows Jakiro to prevent Treant Protector from using 
Overgrowth while staying at a safe distance.
Jakiro
* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of his abilities without a Black King Bar.
* With the Aghanim's Scepter upgraded Macropyre, Black King Bar becomes nearly useless for Crystal Maiden, as its high pure damage over time, long duration and ability to pierce spell immunity will either force Crystal Maiden to forcefully cancel Freezing Field or even discourage her from using it at all.
Additional:
* Ice Path allows Jakiro to easily cancel Freezing Field.
* Freezing Field makes Crystal Maiden an easy target for all of Jakiro's abilities without a Black King Bar.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, making Black King Bar nearly useless for Crystal Maiden, as its high damage over time and long duration can discourage Crystal Maiden to use Freezing Field. Remember, however, that Crystal Maiden can partially solve this issue by buying Aghanim's Shard, which will allow her to simply walk out of Macropyre.
Jakiro
* Jakiro's area of effect abilities can hit Dark Willow even while she is hidden during the 
Shadow Realm.
* Waiting about 2 seconds after Dark Willow casts Shadow Realm to cast Ice Path will stun her while her Shadow Realm is at it's maximum damage.
* Jakiro can stun Dark Willow when there is about 1 second left on 
Cursed Crown, Jakiro's Ice Path stun lasts slightly longer then Cursed Crown.
Medusa
* Mana Shield can tank most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.
Jakiro
* 
Death Ward can be easily canceled by Jakiro, or even turned against him with Macropyre, due to it's attack range being smaller then Jakiro's cast range. And Crystal Maiden, his Scepter does not allow him to move while using it. 
Voodoo Switcheroo is even easier to land Jakiro's Macropyro/Ice Path combo. And unlike Crystal Maiden, Witch Doctor's Aghanim's Scepter upgraded Death Ward does not allow him to move while using it.
* While 
Maledict can be quite effective on Jakiro, along with repetitive stuns from Paralyzing Cask, it is very difficult to get a strong Maledict on him. Although Witch Doctor's Paralizying Cask, Maledict and Death Ward combo will still quickly eliminate Jakiro.
* On the other hand. 
Voodoo Restoration will partly protect his allies from Jakiro spells, as it heals based on their Max Health once he gets his Talent (Level 25). Before then though, it won't make a dent in the damage Jakiro deals.
Jakiro
* Both Jakiro's Ice Path and Liquid Frost can be used to cancel 
Life Drain from either Jakiro or an ally.
* 
Decrepify only makes Pugna even more vulnerable to Jakiro's magical damage, And it has no adverse effects on Jakiro himself.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce debuff immunity, which can discourage Pugna from even trying to use Life Drain.
* Bear in mind, however, that 
Nether Ward can do some considerable damage to Jakiro due to high mana costs on his abilities.
Jakiro
* Jakiro has 3 damage over time spells, 2 of which are from debuffs on Puck (Dual Breath and Liquid Fire) and 1 affecting an entire area (Macropyre), making it easy for him to disable the Blink Dagger.
* Ice Path is also strong against Puck, as he can cast it towards Puck during Phase Shift, who then gets instantly stunned once Phase Shift ends.
Additional:
* Jakiro has 3 damage over time spells, 3 of which are from debuffs on Puck: Dual Breath, Liquid Fire and Liquid Frost from Aghanim's Shard from and 1 affecting an entire area (Macropyre), making it easy for him to disable the blink dagger.
* Ice Path is also strong against Puck, as he can cast it towards Puck during Phase Shift, who then gets instantly stunned once Phase Shift ends.
Medusa
* Axe can take advantage of Medusa's awfully low HP to insta-kill her with 
Culling Blade, making it extremely difficult for her to farm for items to compensate for the lack of strength during early and mid-game while Axe is continuously harassing around.
Jakiro
* Ice Path is a great stun for Berserker's Call and with a 
Eul's Scepter of Divinity can really catch Axe off guard.
* Dual Breath and Liquid Fire can be a devastating combination for Axe (especially if he takes Battle Hunger at level 1) before he has any natural regeneration sustain from items.
Additional:
* Ice Path neutralizes initiation attempts with Berserker's Call, and its long area of effect discourages follow-ups from Axe's teammates until Axe buys Black King Bar.
* Ice Path serves as a large obstacle to stop Axe from chasing down fleeing stragglers to kill with Culling Blade until Axe buys Black King Bar.
* Jakiro's many damage-per-second skills prevent Axe from initiating with his Blink Dagger. Forcing Axe to buy Black King Bar prematurely to protect himself against Jakiro's abilities and counter-initiaions.
Medusa
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.
Jakiro
* Jakiro's area-of-effect abilities that deal magical damsge make it hard for Omniknight to save multiple enemy heroes at once with 
Purification and 
Repel, and 
Guardian Angel and to harass Omniknight on lane.
* Aghanim's Scepter upgraded Macropyre allows Jakiro to deal pure damage and slow enemy heroes which can pierce debuff immunity, rendering both Repel and Guardian Angel useless.
Medusa
* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.
Jakiro
* Both Ice Path and Macropyre are the good setup against Earthshaker after he jumps in with Blink Dagger, and stay out of Echo Slam initiation radius.
* Jakiro's damage over time abilities can potentially disable Earthshaker's Blink Dagger.
Medusa
* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.
Jakiro
* All of Jakiro's active skills can be targeted on an area, which is effective at forcing Templar Assassin to move should she 
Meld away.
* Many of Jakiro's spells utilize damage-over-time mechanics, which makes it easy to strip away layers of 
Refraction.
Jakiro
* Heroes with good mobility to avoid Jakiro's abilities and with good chase to punish Jakiro from pushing a tower: Bloodseeker, Ember Spirit, Juggernaut, Phantom Assassin, Weaver.
Jakiro
* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, 
Troll Warlord, Keeper of the Light.
Medusa
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, 
Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa, 
Warlock.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Medusa
* Heroes with Linken's Sphere as core item: Weaver, 
Morphling, Medusa.
Jakiro
* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.
Jakiro
* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Jakiro
* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.
Jakiro
* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.
Jakiro
* Jakiro's early pushing ability from Liquid Fire makes Jakiro very strong against heroes, that take a long time to get online: Morphling, Naga Siren, Spectre.
Jakiro
* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, Enigma, Pudge, Shadow Fiend, Shadow Shaman, Warlock.
Jakiro
* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Jakiro
* Jakiro's wide area-of-effect abilities allow him to clear the waves of Terrorblade's illusions and to damage real Terroblade.
* Both, Liquid Fire and Liquid Frost from Aghanim's Shard deal magical damage, which can bypass Terrorblade's high armor.
* Jakiro often buys Hurricane Pike, which combined with +275 Attack Range talent allows Jakiro to harass Terrorblade from safe distance without getting in range of 
Sunder and outrange Terrorblade greatly, even during 
Metamorphosis.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Terrorblade and his illusions and can hurt real Terrorblade even if he is protected by Black King Bar thanks to it's ability to pierce spell immunity when upgraded.
* Just bear in mind, however, that Jakiro's abilites are all dealing damage-over-time, so a well-timed Sunder may spell a doom for Jakiro if Terrorblade can get close to him unless Jakiro builds Black King Bar or Linken's Sphere and other items that can give him a burst damage.
Additional:
* Jakiro's wide area-of-effect abilities allow him to clear the waves of Terrorblade's illusions and to damage real Terroblade.
* Both, Liquid Fire and Liquid Frost from Aghanim's Shard deal magical damage, which can bypass Terrorblade's high armor.
* Jakiro often buys Hurricane Pike, which combined with +275 Attack Range talent allows Jakiro to harass Terrorblade from safe distance without getting in range of Sunder and outrange Terrorblade greatly, even during Metamorphosis.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Terrorblade and his illusions and can hurt real Terrorblade even if he is protected by Black King Bar thanks to it's ability to pierce spell immunity when upgraded.
* Just bear in mind, however, that Jakiro's abilites are all dealing damage-over-time, so a well-timed Sunder may spell a doom for Jakiro if Terrorblade can get close to him unless Jakiro builds Black King Bar or Linken's Sphere and other items that can give him a burst damage.
Jakiro
* Heroes with good mobility to avoid Jakiro's abilities and with good chase to punish Jakiro from pushing a tower: Bloodseeker, Ember Spirit, Juggernaut, Phantom Assassin, Weaver.
Jakiro
* Weaver has poor health, relying on 
Shukuchi and 
Time Lapse to survive, With Jakiro's considerable arsenal of stuns, Weaver cannot initiate on Jakiro without being punished heavily or even killed in return.
* While difficult, Ice Path can catch Weaver during Shukuchi, And since Shukuchi only lasts 4 seconds while Ice Path's stun lasts 3.5, the stun from Ice Path will strip him of his escape.
* Weaver has to be very careful casting Time Lapse around Jakiro, as it could very easily put him inside of a Macropyre or Ice Path.
Jakiro
* Heroes with good mobility to avoid Jakiro's abilities and with good chase to punish Jakiro from pushing a tower: Bloodseeker, Ember Spirit, Juggernaut, Phantom Assassin, Weaver.
Medusa
* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.
Jakiro
* Heroes with good counter-push abilities to clear creep waves can hinder Jakiro's early pushing ability: Death Prophet, Sniper, Tinker, Windranger.
Jakiro
* Tinker's 
Laser has very little effect on Jakiro.
* Tinker has to sit still for a short period of time due to 
Rearm, not only making it easy to catch him with Ice Path, but also by stunning him while he is Rearming, Jakiro generally spell Tinker's doom.
* With s high area-of-effect and strong damage-over-time capabilties, Jakiro can quickly burn through his 
Defense Matrix, and at the same time lock down his Blink Dagger. Both of which he relies heavily to survive on.
Medusa
* Phantom Lancer with Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* 
Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.
Jakiro
* Jakiro's spells inflict AoE damage, meaning he can take down Phantom Lancer's illusion army very quickly.
* Bear in mind, however, that once Phantom Lancer buys Diffusal Blade which can burn Jakiro's mana, Jakiro will be vulnerable to Phantom Lancer 's counter-attacks if he runs out of mana.
Additional:
* Jakiro's AoE abilities are great against Phantom Lancer:
* Dual Breath slows down and damages Phantom Lancer and his illusions.
* Liquid Fire will not only deal AoE damage but also lowers Phantom Lancer's attack speed.
* Ice Path and Macropyre combo can easily clear all of Phantom Lancer's illusions.
* Jakiro can predict Doppelganger and Ice Path on top.
Jakiro
* Heroes with good counter-push abilities to clear creep waves can hinder Jakiro's early pushing ability: Death Prophet, Sniper, Tinker, Windranger.
Jakiro
* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.
Medusa
* With 
Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
* He can deal a huge amount of damage through 
Cloak and Dagger, even through Mana Shield.
Jakiro
* Riki can easily be caught in an Ice Path and Macropyre combo as he finishes 
Tricks of the Trade, Jakiro just has to be careful about Riki's Smoke Screen when dealing with Riki.
Medusa
* Heroes with extremely slow movement speed will cripple against Solar Bind: Medusa, Viper
Additional:
* 
Will-O-Wisp will keep Medusa busy after she got hit by 
Blinding Light.
Jakiro
* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, Keeper of the Light.
Medusa
* Medusa lacks mobility or escape mechanisms. 
Earth Spike and 
Hex can neutralize her strong damage potential and allow for Lion's team to focus her down.
* 
Mana Drain is a perfect ability to weaken Medusa's durability as it can quickly drain her Mana Shield, making her far less tanky. Mana Drain can also be used to restore mana of Lion's allies, which can nullify the mana steal from Mystic Snake.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.
Jakiro
* Mana Drain can be easily canceled with Ice Path. However, Lion can counter this by buying his Aghanim's Shard though, that is no longer possible, but Jakiro can counter this too with Aghanim's Scepter upgraded Macropyre will deal pure damage through the debuff immunity forcing Lion to cancel it or die.
* Lion has very strong single target capabilities, but usually struggles against multiple heroes, while Jakiro has good multi-target capabilities, His abilities also have a much shorter cast range then Jakiro's, allowing Jakiro to cast his abilities before he can get off his Hex or Earth Spike.
* Jakiro can also save an ally who Lion is attempting to 
Finger of Death by casting Ice Path on Lion.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Jakiro
* Jakiro's early pushing ability from Liquid Fire makes Jakiro very strong against heroes, that take a long time to get online: Morphling, Naga Siren, Spectre.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.
Medusa
* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, 
Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away all of Medusa's mana.
Additional:
* 
Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.
Jakiro
* Broodmother and her Spiderlings need to be very careful during the laning stage against Jakiro, as Jakiro can take down Broodmother's Spiderlings, preventing her from pushing as well as gaining a good amount of gold.
Medusa
* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* 
Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. He can force her to use Manta Style before he has cast 
Global Silence and Medusa usually does not want to build Black King Bar.
Jakiro
* Even though carry Silencer can easily take down a support Jakiro with his 
Glaives of Wisdom, Jakiro can also do the same to Silencer if he is not careful and if Jakiro is not played as support. As Silencer is rather squishy and lacks escape mechanisms without items, and Jakiro's damage over time abilities can take advantage of this.
* Ice Path can be used to prevent Silencer from escaping. And if Jakiro uses Ice Path along with Macropyre and Dual Breath in anticipation right before Silencer uses his abilities to disable Jakiro, Jakiro will be able to kill Silencer before he even gets a chance to do anything to Jakiro.
* Dual Breath, Liquid Fire and Liquid Frost from Aghanim's Shard can greatly reduce Silencer's attack speed.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Silencer even if Silencer is spell immune.
* Bear in mind, however, that Jakiro should approach Silencer carefully as Silencer's Arcane Curse, 
Last Word and Global Silence prevents Jakiro from casting any spell. Jakiro, however, can counter this by going for 
Guardian Greaves, a common item on support Jakiro, and with Black King Bar and Manta Style, a situational items on Jakiro.
Additional:
* Even though carry Silencer can easily take down a support Jakiro with his Glaives of Wisdom, Jakiro can also do the same to Silencer if he is not careful and if Jakiro is not played as support. As Silencer is rather squishy and lacks escape mechanisms without items, and Jakiro's damage over time abilities can take advantage of this.
* Ice Path can be used to prevent Silencer from escaping. And if Jakiro uses Ice Path along with Macropyre and Dual Breath in anticipation right before Silencer uses his abilities to disable Jakiro, Jakiro will be able to kill SIlencer before he even gets a chance to do anything to Jakiro.
* Dual Breath, Liquid Fire and Liquid Frost from Aghanim's Shard can greatly reduce Silencer's attack speed.
* Aghanim's Scepter upgraded Macropyre can deal huge pure damage to Silencer even if Silencer is spell immune.
* Bear in mind, however, that Jakiro should approach Silencer carefully as Silencer's Arcane Curse, Last Word and Global Silence prevents Jakiro from casting any spell. Jakiro, however, can counter this by going for Guardian Greaves, a common item on support Jakiro, and with Black King Bar and Manta Style, a situational items on Jakiro.
Medusa
* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.
Jakiro
* Jakiro relies entirely on dealing damage through his area-of-effect abilities, making 
Enfeeble less effective against him, although it will still reduce his cast range.
* An ill-timed 
Nightmare can give Jakiro a good setup for all of his ablities.
* Jakiro can easily cancel Fiend's Grip with Ice Path, as Bane is very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Bane from even trying to use Fiend's Grip.
Additional:
* Jakiro relies entirely on dealing damage through his area-of-effect abilities, making Enfeeble less effective against him, although it will still reduce his cast range.
* An ill-timed Nightmare can give Jakiro a good setup for all of his ablities.
* Jakiro can easily cancel Fiend's Grip with Ice Path, as Bane is very easy target while channeling it.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Bane from even trying to use Fiend's Grip.
Jakiro
* 
Rage grants Lifestealer immunity to all of Jakiro's spells. Note: magic resistance will not dispel the attack speed slow effects from Dual Breath and Liquid Fire.
Medusa
* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces Rage, wasting its cooldown and making Lifestealer unable to fight.
Jakiro
*
Blink allows Anti-Mage to both, escape from Jakiro and to hunt down Jakiro, who has no way to escape without items.
Counterspell protects Anti-Mage against Jakiro's mostly-magical damage.
Mana Void and 
Mana Burn is very hazardous for Jakiro because of his high mana.
*
* Both
Medusa
* Anti-Mage easily destroys
Mana Shield with Mana Break, especially once he has 
Manta Style.
Stone Gaze with Blink, and can reinitiate after its duration is over.
Mana Break burns Medusa's mana easily, especially when coupled with a 
Manta Style.
Blink, burning her mana or forcing her to use Stone Gaze.
Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.
* Anti-Mage effectively avoids
Additional:
*
* Can easily initiate on Medusa with
*