* X Marks the Spot is good to prevent a single meepo from escaping from a deadly situation.
* Tidebringer, Torrent and Ghostship destroys Meepo's clones.
Additional:
* Tidebringer's cleave damage can wear down Meepo's clones quickly. It can also give Meepo problems in the lane, due to his melee range and initially low health pool.
* Ghostship and Torrent can effectively disable Meepo while dealing heavy damage.
* X Marks the Spot prevents attempts to escape using Poof.

* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.

* Tidebringer's cleave will cripple any of his summons.
* Could potentially build Heaven's Halberd to cripple Lycan even more.
Additional:
* Tidebringer can be used to kill Lycan's summons.
* Can also build into Heaven's Halberd which will disable Lycan's auto attacks, crippling him even more.

* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake

* Heroes with cleave or multi-target attacks can quickly take on Familiars and reduce Visage's firepower like Gyrocopter, Kunkka, Magnus and Medusa.

* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.

* Heroes with long range abilities are also able to touch Zeus, such as Clockwerk, Kunkka, Puck, Skywrath Mage, Spirit Breaker, Tusk and others.

* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Heroes with strong area-of-effect damage can make quick work of Chen's converted creeps and at same time gain farm: Magnus, Jakiro, Shadow Fiend, Kunkka, Luna, Dragon Knight, Medusa, Alchemist.

* Heroes with strong area-of-effect damage can make quick work of Chen's converted creeps and at same time gain farm: Magnus, Jakiro, Shadow Fiend, Kunkka, Luna, Dragon Knight, Medusa, Alchemist.

* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.

* Ghostship helps your team soak up damage from Sonic Wave and Scream of Pain.
* Queen of Pain can't escape easily from X Marks the Spot - Torrent combo.

* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.

* Tidebringer will deal lots of damage to Alchemist before he builds physical survivability items.
* Torrent and X Marks the Spot can control Alchemist at all stages of the game before he has Black King Bar.
* Ghostship's rum buff will greatly reduce the Alchemist's damage output in teamfights including his Radiance.

* Tidebringer, Torrent and Ghostship destroys Chaos Knight's Phantasm army all through the game.

* Ghostship can stun Faceless Void and give damage reduction to allies that are trapped during Chronosphere.
* Torrent can stun Faceless Void from outside Chronosphere.
* X Marks the Spot can bring back Faceless Void if he escapes using Time Walk.
* If the timing is right and there are allies to attack, a combination of X Marks the Spot, Ghostship, Torrent and Tidebringer can kill Faceless Void instantly.

* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.

* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to manfight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalise on his commitment in a fight.

* X Marks the Spot breaks Flaming Lasso when used on ally and can break if used on Batrider.

* X Marks The Spot allows Kunkka or his teammates to fight back under effect of Glimpse.

* Using X Marks the spot Kunkka can prevent Ember Spirit from escaping with Activate Fire Remnant, until he purchase Eul's Scepter of Divinity or Linken's Sphere.

* If Medusa activates Stone Gaze, the charge will inevitably fail.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation.

* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.

* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.

* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.

* Ghostship helps your team soak up damage from Epicenter, especially if he initiates during the battle.
* Sand King can't dodge X Marks the Spot - Torrent combo by his abilities. Torrent drags him out of his Sand Storm

* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult.
* Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.

* Mana Shield tanks most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.

* Ghostship helps your team soak up damage from Chaotic Offering and hit summons hard.
* Tidebringer clears summons later in the game.
* Most of your spells can interrupt Upheaval.

* X Marks the Spot will return Underlord or his teammate if they escape with Dark Rift.

* X Marks the Spot negates Stampede.

* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.

* X Marks the Spot prevents Dark Seer or his allies from escaping with Surge.

* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa.

* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.
* In general, highly mobile heroes like Earth Spirit or Storm Spirit are at a disadvantage against X Marks the Spot.
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.

* Heroes that can negate Hoodwink's mobility: Kunkka, Disruptor, Mars.

* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.

* Heroes with long channeling abilities like Witch Doctor are easy targets for Kunkka to interrupt in team fights.

Additional:
* Torrent can cancel Death Ward from a far distance.

* In general, highly mobile heroes like Earth Spirit or Storm Spirit are at a disadvantage against X Marks the Spot.
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.

* In general, highly mobile heroes like Earth Spirit or Storm Spirit are at a disadvantage against X Marks the Spot.
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.

* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.

* Heroes with Linken's Sphere as core item: Weaver, Morphling, Medusa.

* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.
* In general, highly mobile heroes like Earth Spirit or Storm Spirit are at a disadvantage against X Marks the Spot.
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.

Additional:
* X Marks the Spot can be used to prevent Tinker from escape with Blink Dagger or Boots of Travel, discourage him from snapping farm and snapping gank. However, in later game, it'll be much more difficult because Tinker can buy Black King Bar or Linken's Sphere to prevent Kunkka from placing X on him, or Eul's Scepter of Divinity to prevent the recall

* Medusa's Split Shot will whittle down all of Naga Siren's illusions, including Naga Siren herself.

* Spectre can't escape with Spectral Dagger under X Marks the Spot.
* Kunkka can dominate Spectre's lane using Tidebringer and gain an advantage.
* Ghostship helps your team soak up damage from Haunt.

* Kunkka's Ghostship and Torrent disrupt fights in Arena Of Blood.

* Medusa's Stone Gaze forces Mars to choose between getting petrified, or turning his vulnerable back on Medusa.

* Tidebringer pressures Invoker easily in lane due to Invoker's low health and armor in the early game.

* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces Rage, wasting its cooldown and making Lifestealer unable to fight.

* Tidebringer, Torrent and Ghostship destroys Phantom Lancer's illusion army.
* Phantom Lancer can't escape with Doppelganger under your X Marks the Spot, but can use it to dodge it.
Additional:
* Tidebringer and Kunkka's AoE abilities in general are effective in clearing Phantom Lancer's illusions.

* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.

* X Marks the Spot prevents Broodmother from escaping.
* Tidebringer can clear Broodmother's spiders if they get in range.
Additional:
* Kunkka's entire kit is great for taking out multiple units at once.
* Tidebringer's cleave will split through a wave of spiderlings.
* X Marks the Spot is great for dragging Broodmother back out of her web for Kunkka's team to set up on her.
* Torrent and Ghostship will demolish any spiderlings within the radius.