* Diabolic Edict and Pulse Nova hit all units around Leshrac, making it very easy for him to kill the Summon Familiars.
* Diabolic Edict and Pulse Nova also deal many instances of damage, nullifying Gravekeeper's Cloak.
* Split Earth and Lightning Storm makes it difficult for Visage to kite Leshrac, even while under the effects of Grave Chill.

* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.

* Pulse Nova deals an insane amount of damage in an area around him, which can quickly wear down Meepo clones.
* Leshrac can catch multiple Meepos in Split Earth and follow up with the rest of his area damage spells making Meepo unable to get close to Leshrac.
* Diabolic Edict is a strong ability that can wear down a lone Meepo clone quickly.

* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.

* Heroes who continue dealing damage while being stunned: Luna, Razor, Axe, Bristleback, Leshrac,

* If Medusa activates Stone Gaze, the charge will inevitably fail.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation.

* Heroes who can clear the waves of Enigma's Eidolons: Lina, Luna, Dawnbreaker, Jakiro, Shadow Shaman, Death Prophet, Keeper of the Light, Invoker, Leshrac, Puck.

* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult.
* Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult.
* Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.

* Leshrac's AoE abilities make quick work of Chen's creep army.

* Heroes with cleave abilities and area of effect damage can make quick work of Chen's converted creeps and at same time gain farm: Magnus, Jakiro, Shadow Fiend, Kunkka, Luna, Dragon Knight, Medusa, Alchemist.

* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,Beastmaster

* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake

* All of Leshrac's abilities, especially Pulse Nova, can easily deal with Naga Siren's illusions.

* Medusa's Split Shot will whittle down all of Naga Siren's illusions, including Naga Siren herself.

* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,Beastmaster

* Heroes with Linken's Sphere as core item: Weaver, Morphling, Medusa.

* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.

* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.

* Pulse Nova can easily burn Templar Assassin's Refraction charges quickly, and can also hit her with her Meld.

* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.

* Diabolic Edict and Pulse Nova will tear apart any illusions spawned from Disruption
* Split Earth can punish improper usage of Disruption.
* Leshrac does not have any buffs that can be removed by Demonic Purge.
Additional:
* Pulse Nova makes quick work of any illusions with amplified damage, and deals damage even if Leshrac is in Disruption.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Split Earth for the enemy.
* Disruption does not stop Diabolic Edict and Pulse Nova once they start pulsing, and even worse it provides a safe shelter for Leshrac to keep pumping up his powerful AoE damage onto the battlefield.
* Leshrac usually builds Eul's Scepter of Divinity to dispel Shadow Poison and Soul Catcher and Linken's Sphere to block Disruption and Demonic Purge.
* Shadow Demon doesn't have the burst damage to take Leshrac out of the fight quickly, although Demonic Purge can help his allies kill a squishy Leshrac.

* Mana Shield tanks most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.

* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to manfight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalise on his commitment in a fight.

* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.

* Io is a hero who needs to be close to it's tethered target to make it effective, and that's where Leshrac gets the advantage thanks to many of his area-of-effect abilities.
* Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to both, Io and its tethered target.
Additional:
* Lightning Storm will usually hit both Io and his Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.

* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.

* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa.

* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain

* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, Phoenix, Alchemist, Earthshaker, Razor, Tinker, Leshrac, Queen of Pain

* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,Beastmaster

* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.

* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.

* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.

* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, Pugna, Death Prophet.

* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.

* Diabolic Edict makes Leshrac very effective at threatening early towers and objectives which can directly cause unfavourable conflicts with Primal Beast early before he has Black King Bar to deal with the magical damage.
* Pulse Nova and the rest of Leshrac's spells can overwhelm Primal Beast with magical damage.
* Leshrac has generally faster movement speed than Primal Beast, especially if he has items such as Boots of Travel and Eul's Scepter of Divinity.
* Bloodstone also makes him heal much more than Primal Beast can damage him at any stage of the game.

* Heroes that have strong area-of-effect abilities and can stall pushes: Invoker, Keeper of the Light, Jakiro, Lina, Luna, Leshrac, Shadow Shaman.

* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces Rage, wasting its cooldown and making Lifestealer unable to fight.

* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.

* Leshrac can easily clear Phantom Lancer's illusions with his huge area of effect damage.
Additional:
* Leshrac's AoE abilities destroy Phantom Lancer's illusions.
* Diabolic Edict and Pulse Nova require no targeting, thus hitting Phantom Lancer whenever he's nearby.

* Your AoE abilities should make quick work of her spiderlings.