Lich
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: 
Disruptor, 
Death Prophet, 
Enigma, 
Faceless Void, 
Invoker, 
Lich, 
Magnus, 
Mars, 
Medusa, 
Outworld Destroyer, 
Phoenix, 
Puck, 
Queen of Pain, 
Shadow Fiend, 
Treant Protector, 
Underlord, 
Winter Wyvern, 
Witch Doctor, 
Zeus.
Brewmaster
* After Brewmaster has committed Thunder Clap and Cinder Brew to gank, Bane can use 
Nightmare on Brewmaster to wait out the debuffs, and might even turn the tables by buying time for allied reinforcements.
* Bane can also prevent Brewmaster from using Primal Split with his long disables.
Lich
* Queen of Pain can easily escape Chain Frost thanks to 
Blink.
* His low survivability makes an easy kill for 
Shadow Strike, 
Scream of Pain & 
Sonic Wave.
Brewmaster
* Blinking heroes like 
Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.
Lich
* Anti-Mage can withstand magical burst damage much better than other carries, making him effective against nukers: Lich, 
Necrophos, 
Oracle, and 
Leshrac.
Additional:
* Although he can be effective against Anti-Mage in an aggro offlane, Lich has a hard time nuking down Anti-Mage in the midgame due to his Counterspell.
* All of Lich's abilities are also targeted, which makes it much harder to disable Anti-Mage.
* In the lategame, Anti-Mage can easily pick off Lich with 
Blink, and the high mana cost of Chain Frost along with Lich's large mana pool makes him vulnerable to 
Mana Void.
* Blink allows Anti-Mage to escape Chain Frost.
Brewmaster
* Blinking heroes like Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.
Lich
* Lich does not pose a big threat to Zeus in teamfights, as his spells don't have great cast range and Zeus should be too far back for a 
Chain Frost to bounce among him and his allies.
* Lich has a low health pool, allowing Zeus to burst him down quickly.
Brewmaster
* 
Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Shaman has used all his crowd control before entering a fight.
* Brewmaster also has no defense against Shadow Shaman lockdowns.
Brewmaster
* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.
Brewmaster
* 
Ancient Seal's instant cast time will often silence Brewmaster before he can do anything.
* Brewmaster also has no defense against Skywrath Mage's massive magical damage.
Lich
* If 
Thirst activated, Lich doesn't slow Bloodseeker.
* If he sees Chain Frost is targeting him, he can easily isolate himself with Thirst or forces Bloodseeker to build 
Blade Mail can cause Lich to accidentally kill himself with Chain Frost.
* Even Lich builds 
Glimmer Cape or 
Force Staff are suicidal item against Bloodseeker when he is affected by 
Rupture.
Brewmaster
* 
Exorcism kills Primal Split's units very quickly.
Brewmaster
* 
Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Lion has used all his crowd control before entering a fight. His direct magic burst also makes Brewmaster's Drunken Brawler worthless versus Lion.
Lich
* Heroes with low health: Lich, 
Crystal Maiden, 
Lion.
Lich
* The haste provided by 
Dark Seer's 
Surge or a {Rune:Haste} renders your slows ineffective.
Lich
* Heroes with low health will die easily during Duels, and can be farmed for damage in the early game: Crystal Maiden, Lich, 
Techies, 
Rubick
Brewmaster
* Heroes with strong team-fight abilities (especially ultimates) like 
Tidehunter, 
Brewmaster, Death Prophet, etc.
Lich
* Heroes who lack burst damage will have a hard time against Mars: 
Phantom Lancer, 
Nature's Prophet, Lich.
Lich
* Chain Frost can bounce to the Spiderlings that Broodmother spawns.
Brewmaster
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: 
Broodmother, Enigma, Nature's Prophet.
Lich
* Chain Frost can bounce to the treants that Nature's Prophet summons.
* Nature's Prophet's 
Sprout can be used to isolate and burst down the squishy Lich.
Additional:
* His treants can prevent Chain Frost from jumping to Nature's Prophet or his allies.
Brewmaster
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.
Lich
* Phantom Assassin can easily escape Lich's slows with 
Phantom Strike.
* Phantom Assassin's 
Coup De Grace can be used to burst down the squishy Lich.
Brewmaster
* In general, Brewmaster's Cinder Brew and Thunder Clap makes him good against physical damage carries: 
Ursa, 
Clinkz, Faceless Void, 
Troll Warlord, 
Templar Assassin, 
Phantom Assassin.
Lich
* 
Frost Shield helps offset the armor reduction from Natural Order.
Brewmaster
* {U:Earth} has passive 
Spell Immunity, allowing him to walk into the Echo Stomp radius to stun Elder Titan with his 
Hurl Boulder.
* {U:Storm}'s 
Cyclone can cancel the channeling of Echo Stomp and take Elder Titan out of the fight for {show:A|Storm|Cyclone|value2} seconds.
Lich
* Chain Frost can eliminate Chaos Knight's 
Phantasm army, especially after he clumped up using 
Reality Rift.
* Frost Shield will heavily reduce his army's effectiveness.
Additional:
* Lich's Chain Frost, especially after obtaining its respective talent that provides unlimited bounces, can take out all of Chaos Knight's illusions quickly.
* An 
Aghanim's Scepter-upgraded 
Sinister Gaze can hypnotize Chaos Knight and his illusions while also draining his already low mana pool.
Brewmaster
* Storm's Dispel Magic combined with Thunder Clap deals high damage against Chaos Knight's illusions even in the late game.
* Chaos Knight's reliance on physical damage is easily hindered by Drunken Brawler.
* Chaos Knight's lack of area effect and mobility makes him easily overwhelmed by Primal Split.
Additional:
* 
Dispel Magic from {U:Storm} can instantly kill Phantasms early on, and can still deal a lot of damage to them late game, revealing the real Chaos Knight.
Lich
* Chain Frost can deliver high amounts of damage to Lone itself and his bear if they do not separate fast from each other.
Additional:
* Chain Frost will bounce between Lone Druid and his bear, forcing them to separate or suffer high amounts of damage.
Brewmaster
* Brewmaster can make the Spirit Bear a much smaller threat with Cinder Brew.
* Cyclone removes the bear from a fight so that his team can easily focus on the hero.
* While most heroes would be worn down by a Spirit Bear 
Radiance in the time it takes to kill Lone Druid, Brewmaster is protected in Primal Split.
Lich
* Heroes with large magical AoE damage will fare well against Omniknight: Lich, 
Ancient Apparition, 
Jakiro, Disruptor.
Brewmaster
* Dispel Magic from {U:Storm} instantly removes Heavenly Grace and Guardian Angel from Omniknight's allies in its radius of effect.
Lich
* 
Frost Blast and Chain Frost can kite Troll Warlord effectively.
* Frost Shield can single-handedly waste most of the duration of Battle Trance, due to the extreme resistance to physical damage Frost Shield provides. In addition, Troll Warlord is incapable of switching targets during Battle Trance, so he cannot pick an easier target.
* Troll Warlord has little to no ability to regenerate HP, so Frost Blast together with Frost Shield can harass him effectively.
Brewmaster
* In general, Brewmaster's Cinder Brew and Thunder Clap makes him good against physical damage carries: Ursa, Clinkz, Faceless Void, Troll Warlord, Templar Assassin, Phantom Assassin.
Lich
* Lich's constant slows with Frost Blast and Chain Frost will slow Dragon Knight to a crawl, especially in a crowded teamfight.
Brewmaster
* 
Cinder Brew and 
Drunken Brawler makes it hard for Monkey King to stack Jingu Mastery.
* Cyclone can remove Monkey king for 6 seconds if his allies lack dispels.
* Dispel Magic can dispel Jingu Mastery's bonuses.
Brewmaster
* 
Thunder Clap and Drunken Brawler prevent Faceless Void from maximising his damage potential in fights.
* Cyclone disables Faceless Void during Chronosphere or in general.
Brewmaster
* 
Primal Split makes Brewmaster invulnerable for the duration, rendering effects of Cold Feet and Ice Blast useless.
* Dispel Magic can dispel Cold Feet from allies.
* Brewmaster can easily run Ancient Apparition down with the slow from Thunder Clap and Cinder Brew.
Brewmaster
* Cyclone from Storm in Primal Split can waste Nyx's Spiked Carapace, since its duration is shorter than the Cyclone's.
Lich
* Lich's Chain Frost forces Io to either give up providing buff to his ally with 
Tether or suffer devastating damage with his tethered ally.
* Lich can easily use Sinister Gaze to disable Io from getting away with Tether or 
Relocate.
Brewmaster
* Dispel Magic can remove Abaddon's 
Aphotic Shield or 
Curse of Avernus on an allied hero.
* Cyclone's lengthy duration wastes much of 
Borrowed Time's duration.
Additional:
* {U:Storm} can use Cyclone on Abaddon when he activates Borrowed Time, wasting its duration.
* Drunken Brawler and Thunder Clap hinder Abaddon from applying Curse of Avernus' silence on him.
Lich
* Chain Frost can deliver high amounts of damage to Arc and his clone
Lich
* 
Poof combo puts all of the Meepos very close together, making them vulnerable to Frost Blast's AoE slow and multiple bounces from Chain Frost.
Lich
* Heroes with nukes: 
Bane, Lich, Lion, 
Skywrath Mage
Brewmaster
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.
Brewmaster
* Brewmaster with Primal Split
* Heroes that can dodge Glimpse:
* Puck with 
Phase Shift
* 
Riki with 
Tricks of the Trade
* Phantom Lancer with 
Doppelganger
* 
Ember Spirit with 
Sleight of Fist and 
Activate Fire Remnant
* 
Chaos Knight with Phantasm
* 
Naga Siren with 
Mirror Image
* 
Tusk with 
Snowball
* 
Juggernaut with 
Omnislash
* Brewmaster with Primal Split
* 
Lifestealer with 
Infest
* Phoenix with 
Supernova
Brewmaster
* Heroes with evasions: Phantom Assassin, Brewmaster, 
Hoodwink, 
Windranger.
Additional:
* If Ursa uses 
Enrage Brewmaster can use Cyclone to render him harmless during his ultimate.
* Brewmaster has two spells to slow down Ursa, allowing his team to kite around him easily.
Lich
* Supports who can slow him to the point Trample does very little damage in the lane are also not fun: Lich, 
Ogre Magi, Winter Wyvern.
Brewmaster
* Heroes that excel at grouping up with their team very early will be able to take advantage of a Clinkz that tries to pick off heroes that are alone: Brewmaster, 
Dazzle, Tidehunter.
Brewmaster
* Heroes with area dispel can kill multiple skeletons at once: Brewmaster, Oracle.
Lich
* Heroes with powerful nuke can waste their precious abilites on her Refraction during a ganking attempt or chaos combat: Lich, 
Lina, 
Sniper, Outworld Destroyer Zeus
Brewmaster
* The three Primal Split brewlings all attacking Templar Assassin at once will remove her 
Refraction quickly, especially with Fire's Permanent Immolation.
* Templar Assassin has no way to stop Brewmaster from using Primal Split by herself, and may get unlucky and miss her 
Meld if trying to burst him during her ally's disable.
Lich
* Lycan doesn't care much about Lich's slows thanks to 
Shapeshift.
* Chain Frost can bounce to the wolves that Lycan summons.
Additional:
* Lich possesses a lot of slows, which Lycan doesn't care about when he Shapeshifts.
* Lich has no in-built escape, which makes him a good target for Lycan.
Brewmaster
* Brewmaster can waste a large portion of Lycan's ultimate by putting him in Cyclone.
* Lycan has no way to stop Brewmaster from using Primal Split by himself.
* Lycan's team often tries to push towers as a group, and Brewmaster excels at winning teamfights while trying to defend a tower.
Lich
* Lich is going to have a hard time nuking Huskar because of his high health regeneration from 
Berserker's Blood.
* Lich is a squishy support without an escape mechanism, making Lich an easy kill thanks to 
Life Break and 
Burning Spear.
* Once Huskar has 
Armlet of Mordiggian, even a maxed out Frost Blast will struggle to finish Huskar off.
Brewmaster
* Brewmaster can use Cyclone to disable Huskar's healer for much longer than most other heroes can, to make Huskar vulnerable.
* Huskar has no way to stop Brewmaster from using Primal Split by himself, but can cut a good amount of his high health away if Huskar's team wants to burst Brewmaster down during a different disable.
Lich
* Weaver doesn't care much about Lich's slows thanks to
Shukuchi.
Time Lapse.
* If he sees Chain Frost is targeting him, he can easily isolate himself with Shukuchi so that it stops bouncing around.
* Unless Lich bursts Weaver immediately, Lich has no hard disables or silences to prevent him from using
Brewmaster
* Brewmaster is slow and has low armor, making his laning stage very difficult against Geminate Attack.
Hurl Boulder, which can be disjointed, he has no control to catch Weaver.
* Apart from the slow moving