* Supports who can slow him to the point Trample does very little damage in lane are also not fun: Lich, Ogre Magi, Winter Wyvern.

* Silence can be used to interrupt Primal Beast while he is channeling Pulverize.
* Spirit Siphon can whittle down Primal Beast's health and can potentially heal back any burst damage he deals to her.
* Exorcism can shed Primal Beast's health down while he attempts to complete any skill combos during a fight with it active.

* Lich's Chain Frost forces Io to either give up providing buff to his ally with Tether or suffer devastating damage with his tethered ally.
* Lich can easily use Sinister Gaze to disable Io from getting away with Tether or Relocate.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Lich's constant slows with Frost Blast and Chain Frost will slow Dragon Knight to a crawl, especially in a crowded teamfight.

* Because Timbersaw relies heavily on his spells to deal damage, Silence can easily disable him in a team fight.
* Exorcism's spirits do not count as regular attacks, and will not add stacks of Reactive Armor.

* Lich's Chain Frost, especially after obtaining its respective talent that provides unlimited bounces, can take out all of Chaos Knight's illusions quickly.
* An Aghanim's Scepter-upgraded Sinister Gaze can hypnotize Chaos Knight and his illusions while also draining his already low mana pool.
Additional:
* Chain Frost can eliminate Chaos Knight's Phantasm army, especially after he clumped up using Reality Rift.
* Frost Shield will heavily reduce his army's effectiveness.

* Spirit Siphon exploits her naturally high HP to deal a good amount of DPS. She may break the link with Rebound, but Silence covers that problem.
* Marci's poor armor makes her vulnerable to Exorcism.

* Spirit Siphon and Exorcism can damage through his Resonant Pulse shields.
* Silence can prevent Void Spirit escape or contributing much in fights.

* Quas-Exort Invoker is also a good matchup due to the fact he has no Wex to run faster due to the movement impairment on his stealth. The Forge Spirit and Cold Snap combo doesn't harm her as well since you can drain Invoker's HP with Spirit Siphon which forces him to retreat.
* Silence also prevents Invoker from using Invoke or casting his main spells temporarily. There is no way Invoker can block it unless he has Eul's Scepter of Divinity to cyclone himself or has help from allies.

* Exorcism's ghosts will automatically clear all Proximity Mines revealed when Death Prophet walks near them, provided that the ghosts do not have a specific target at that time.
* Death Prophet is a natural Eul's Scepter of Divinity carrier, meaning she can easily escape a Blast Off initiation.

* Kraken Shell neither dispels nor provides damage reduction against Spirit Siphon. This ability also drains health based on percentage damage, making Tidehunter's large healthpool a very appealing target. Furthermore, the health gained from the Siphon is independent from the amount of damage dealt, so Death Prophet will always heal a large amount of from Tidehunter's pool even if Tidehunter has magic reduction items or abilities on him, which makes her an untargetable enemy for you as this easily outweights any damage output you can provide.
* Exorcism is yet another ability from which Kraken Shell provides no useful protection, as the spirits completely ignore the damage block and are unaffected by the dispel. This ability also creates an unfriendly area where your blink will be constantly cancelled, reducing your ability to land a good Ravage.
* Ravage does not stop neither Spirit Siphon nor Exorcism, making the ability mostly ineffective against her. Additionally, Death Prophet usually builds Eul's Scepter of Divinity, which can be used to dodge the stun entirely.

* Frost Blast and Chain Frost can kite Troll Warlord effectively.
* Frost Shield can single-handedly waste most of the duration of Battle Trance, due to the extreme resistance to physical damage Frost Shield provides. In addition, Troll Warlord is incapable of switching targets during Battle Trance, so he cannot pick an easier target.
* Troll Warlord has little to no ability to regenerate HP, so Frost Blast together with Frost Shield can harass him effectively.

* Frost Shield helps offset the armor reduction from Natural Order.

* Death Prophet abilities disables Earthshaker's Blink Dagger.
* Silence can be used to silence Earthshaker after he blinks in, preventing him from executing his combo.

* Death Prophet's Silence allows her to prevent Bounty Hunter from escaping with Shadow Walk.
* If Bounty Hunter cannot escape with Shadow Walk while affected by Silence, she will be able to burst him down with Crypt Swarm and Spirit Siphon.

* Silence will prevent Chen from activating Hand of God.
* Crypt Swarm and Exorcism can clear Chen's creeps and heavily damage Chen.
* Spirit Siphon heavily damages Chen and slows him, while healing Death Prophet.

* Exorcism kills Primal Split's units very quickly.

* Chain Frost can deliver high amounts of damage to Arc and his clone

* Chain Frost can deliver high amounts of damage to Lone itself and his bear if they do not separate fast from each other.
Additional:
* Chain Frost will bounce between Lone Druid and his bear, forcing them to separate or suffer high amounts of damage.

* Poof combo puts all of the Meepos very close together, making them vulnerable to Frost Blast's AoE slow and multiple bounces from Chain Frost.

* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage

* Spirit Siphon does a lot of magical damage, especially in the early game. This allows her to demolish low health heroes such as Zeus, Pugna, especially when combined with her other spells.

* Death Prophet is a terrible Flaming Lasso target if Exorcism has already been used, since it can still damage Batrider and his teammates, but if Batrider manages to Lasso her before that, it can lead to Death Prophet being quickly burst down.

* Windranger heavily relies on her abilities for any form of tactical advantage and damage. A well timed silence will make her useless: Puck,Silencer, Death Prophet, Skywrath Mage, Drow Ranger, Earth Spirit, Grimstroke.

* Any heroes with stuns or silences: Death Prophet, Lion, Shadow Shaman, Skywrath Mage

* With 4 active abilities, Shadow Shaman is weak against silencing foes such as Silencer, Drow Ranger and Death Prophet.

* In the same vein, heroes with silences — especially with the AoE ones like Death Prophet's Silence — can also prevent Crystal Maiden from being able to impact a fight.

* A couple of long-range heroes with excellent laning like Mirana, Lina, Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.

* Heroes who can clear the waves of Enigma's Eidolons: Lina, Luna, Dawnbreaker, Jakiro, Shadow Shaman, Death Prophet, Keeper of the Light, Invoker, Leshrac, Puck.

* Silence (and mana burns) will be a persistent problem for Phoenix, as it is heavily reliant on its abilities whether defensively or offensively, so heroes like Death Prophet, Skywrath Mage, and even Nyx Assassin must be closely observed to prevent being shut down by these heroes.
* Hexes are a greater threat to Phoenix as they also disable items, preventing Phoenix from dispelling the debuff on its own.

* Because all of Warlock's abilities are active abilities, silences can make his impact in fights minimal. Be cautious of heroes that carry silences like Death Prophet, Puck, and the aforementioned Silencer.

* Heroes with good counter-push abilities to clear creep waves can hinder Jakiro's early pushing ability: Death Prophet, Sniper, Tinker, Windranger.

* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .

* Heroes who can silence will shut down Dark Willow entirely: Death Prophet, Silencer, Drow Ranger

* Heroes with silencing abilities can be particularly deadly when Slark is trying to escape: Silencer, Death Prophet, Puck, Doom.

* Death Prophet is able to Silence Undying up to 6 seconds. Besides, due to Undying's high strength during a team fight, Spirit Siphon is a powerful ability against Undying thanks to the percentage health drain.

* While Morphling can burst her down with Adaptive Strike (Agility), Death Prophet does have tools to disrupt him. A Morphling affected by Silence makes it unable to use Attribute Shift (Strength Gain) to increase its health pool or use Waveform to escape.

* Crypt Swarm can quickly kill any Treants. Silence also prevents him from using Teleportation to escape or Sprout to lock you down.
Additional:
* Crypt Swarm helps clear waves of Treants.
* Silence prevents Nature's Prophet from using Sprout or Teleportation.
* Exorcism kills Treants with ease.

* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, Pugna, Death Prophet.