Lich
* Bloodseeker is not affected by slows when he is affected by 
Thirst.
* If he sees Chain Frost is targeting him, he can easily isolate himself with the movement speed buff from Thirst so that it stops bouncing around.
* Lich heavily relies on his abilities to contribute to team fights, making 
Blood Rite effective against him.
Lich
* Chain Frost can bounce to the Spiderlings that Broodmother spawns.
Lich
* Lich is going to have a hard time nuking Huskar because of his high health regeneration from 
Berserker's Blood.
* Lich is a squishy support without an escape mechanism, making Lich an easy kill thanks to 
Life Break and 
Burning Spear.
* Once Huskar has 
Armlet of Mordiggian, even a maxed out Frost Blast will struggle to finish Huskar off.
Lich
* Lycan doesn't care much about Lich's slows thanks to 
Shapeshift.
* Chain Frost can bounce to the wolves that Lycan summons.
Additional:
* 
Lich possesses a lot of slows, which Lycan doesn't care about when he Shapeshifts.
* Lich has no in-built escape, which makes him a good target for Lycan.
Lich
* Chain Frost can bounce to the treants that Nature's Prophet summons.
* Nature's Prophet's 
Sprout can be used to isolate and burst down the squishy Lich.
Additional:
* His treants can prevent 
Chain Frost from jumping to Nature's Prophet or his allies.
Primal Beast
* Oracle can negate and shut down Primal Beast simply with Fate's Edict, especially in the early game, as a majority of his damage-dealing spells are magic.
* Oracle can interrupt Primal Beast's 
Onslaught charge with a well-timed Fortune's End.
* Primal Beast's lethal burst damage combos can be further stalled with False Promise; combined with Fate's Edict and regen from Purifying Flames, Oracle can even completely negate Primal Beast's offense.
Lich
* Phantom Assassin can easily escape Lich's slows with 
Phantom Strike.
* Phantom Assassin's 
Coup De Grace can be used to burst down the squishy Lich.
Lich
* Queen of Pain can easily escape Chain Frost thanks to 
Blink.
* His low survivability makes an easy kill for 
Shadow Strike, 
Scream of Pain & 
Sonic Wave.
Lich
* Weaver doesn't care much about Lich's slows thanks to 
Shukuchi.
* If he sees Chain Frost is targeting him, he can easily isolate himself with Shukuchi so that it stops bouncing around.
* Unless Lich bursts Weaver immediately, Lich has no hard disables or silences to prevent him from using 
Time Lapse.
Lich
* Heroes with powerful nuke can waste their precious abilites on her Refraction during a ganking attempt or chaos combat: Lich, 
Lina, 
Sniper, 
Outworld Destroyer 
Zeus
Lich
* Heroes with low health: Lich, 
Crystal Maiden, 
Lion.
Lich
* The haste provided by 
Dark Seer's 
Surge or a {Rune:Haste} renders Lich's slows ineffective.
Lich
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: 
Disruptor, 
Death Prophet, 
Enigma, 
Faceless Void, 
Invoker, Lich, 
Magnus, 
Mars, 
Medusa, Outworld Destroyer, 
Phoenix, 
Puck, 
Queen of Pain, 
Shadow Fiend, 
Treant Protector, 
Underlord, 
Winter Wyvern, 
Witch Doctor, Zeus.
Lich
* Anti-Mage can withstand magical burst damage much better than other carries, making him effective against nukers: Lich, 
Necrophos, 
Oracle, and 
Leshrac.
Additional:
* Although he can be effective against Anti-Mage in an aggro offlane, Lich has a hard time nuking down Anti-Mage in the midgame due to his Counterspell.
* All of Lich's abilities are also targeted, which makes it much harder to disable Anti-Mage.
* In the lategame, Anti-Mage can easily pick off Lich with 
Blink, and the high mana cost of Chain Frost along with Lich's large mana pool makes him vulnerable to 
Mana Void.
* Blink allows Anti-Mage to escape Chain Frost.
Lich
* Heroes with low health will die easily during Duels, and can be farmed for damage in the early game: Crystal Maiden, Lich, 
Techies, 
Rubick
Lich
* Lich is heavily reliant on his abilities to contribute to team fights, so be wary of enemies that can Silence: 
Bloodseeker, Death Prophet, 
Silencer, 
Drow Ranger, 
Skywrath Mage.
Lich
* Lich is heavily reliant on his abilities to contribute to team fights, so be wary of enemies that can Silence: Bloodseeker, Death Prophet, Silencer, Drow Ranger, Skywrath Mage.
Lich
* Heroes who lack burst damage will have a hard time against Mars: 
Phantom Lancer, 
Nature's Prophet, Lich.
Lich
* Lich is heavily reliant on his abilities to contribute to team fights, so be wary of enemies that can Silence: Bloodseeker, Death Prophet, Silencer, Drow Ranger, Skywrath Mage.
Lich
* Chain Frost can deliver high amounts of damage to Arc Warden and his double if they do not separate fast from each other.
Lich
* 
Frost Shield helps offset the armor reduction from Natural Order.
Lich
* Lich's Chain Frost forces Io to either give up providing buff to his ally with 
Tether or suffer devastating damage with his Tethered ally.
* Lich can easily use 
Sinister Gaze to disable Io from getting away with Tether or 
Relocate.
Lich
* Chain Frost can eliminate Chaos Knight's 
Phantasm army, especially after he clumped up using 
Reality Rift.
* Frost Shield will heavily reduce his army's effectiveness.
Additional:
* Lich's Chain Frost, especially after obtaining its respective talent that provides unlimited bounces, can take out all of Chaos Knight's illusions quickly.
* An 
Aghanim's Scepter-upgraded Sinister Gaze can hypnotize Chaos Knight and his illusions while also draining his already low mana pool.
Lich
* Chain Frost can deliver high amounts of damage to Lone Druid itself and his bear if they do not separate fast from each other.
Additional:
* Chain Frost will bounce between Lone Druid and his bear, forcing them to separate or suffer high amounts of damage.
Lich
* 
Poof combo puts all of the Meepos very close together, making them vulnerable to Frost Blast's AoE slow and multiple bounces from Chain Frost.
Lich
* 
Frost Blast and Chain Frost can kite Troll Warlord effectively.
* Frost Shield can single-handedly waste most of the duration of Battle Trance, due to the extreme resistance to physical damage Frost Shield provides. In addition, Troll Warlord is incapable of switching targets during Battle Trance, so he cannot pick an easier target.
* Troll Warlord has little to no ability to regenerate HP, so Frost Blast together with Frost Shield can harass him effectively.
Lich
* Lich's constant slows with Frost Blast and Chain Frost will slow Dragon Knight to a crawl, especially in a crowded teamfight.
Primal Beast
* Long lockdown is a great way to deal with Axe to prevent Berserker's Call from being used, heroes such as 
Legion Commander, 
Beastmaster and 
Primal Beast are good examples of this.
Primal Beast
* Heroes with abilities that can lock down Terrorblade and prevent him from using Sunder: 
Bane, 
Batrider, 
Earthshaker, 
Elder Titan, Faceless Void, Invoker, Legion Commander, Mars, Primal Beast, 
Riki, 
Shadow Shaman, Silencer, 
Vengeful Spirit, 
Void Spirit.
Primal Beast
* Durable heroes: 
Axe, 
Dawnbreaker, 
Bristleback, Mars, 
Omniknight, 
Tidehunter, 
Wraith King, Primal Beast, Underlord.
Primal Beast
* Heroes who have high health are a problem for Sniper because he likes to attack the closest target and sit at the back, much like a 
Terrorblade so when that hero doesn't die; he's forced to show his position for a very long time: 
Centaur Warrunner, Legion Commander, Primal Beast.
Lich
* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage
Lich
* Heroes with large magical AoE damage will fare well against Omniknight: Lich, 
Ancient Apparition, 
Jakiro, Disruptor.
Lich
* Lich is heavily reliant on his abilities to contribute to team fights, so be wary of enemies that can Silence: Bloodseeker, Death Prophet, Silencer, Drow Ranger, Skywrath Mage.
Primal Beast
* Heroes who have low or high armor but very high health will be difficult for drow to burst down quickly: Primal Beast, Axe, Centaur Warrunner.
Lich
* Lich does not pose a big threat to Zeus in teamfights, as his spells don't have great cast range and Zeus should be too far back for a
Chain Frost to bounce among him and his allies.
* Lich has a low health pool, allowing Zeus to burst him down quickly.