* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Lion, Silencer, Shadow Shaman, Grimstroke, Witch Doctor, Riki, Faceless Void, Skywrath Mage, Puck.

* Backline supports (Lion,Crystal Maiden) can keep Puck pinned long enough for a kill.

* Heroes with long disables, like Lion, Night Stalker, or Legion Commander, can prevent Oracle from using spells or items.

* Ranged heroes that can easily harass Axe: Drow Ranger, Sniper, Lion.

* Lion's Mana Drain is a headache for Bristleback to deal with during the laning stage, as it denies him the ability to get last hits with Quill Spray.

* Skywrath's pitiful defences also make him easy meat to heroes with high burst like Juggernaut, Lion, or Phantom Assassin, the latter occasionally downing a support Skywrath in a single Stifling Dagger.

* Heroes with heavy magical nukes will take advantage of Slark's poor HP or force him to use Shadow Dance early: Lina, Lion, Zeus

* Heroes with mana burn: Nyx Assassin, Invoker, Outworld Destroyer, Pugna, Lion

* Hex greatly reduces Timbersaw's mobility.
* In addition, Lion can follow up with his Earth Spike and Mana Drain combo, preventing Timbersaw to escape with Timber Chain. And he can finish Timbersaw off with Finger of Death if the latter's HP is low enough.

* Bramble Maze prevents Timbersaw from Timber Chaining away without getting rooted.
* Cursed Crown can still catch Timbersaw if he Timber Chains away.
* Reactive Armor offers little protection against Dark Willow's high magical damage.

* If Meepo ganks Lion with Poof and Earthbind, he will be an easy target for Earth Spike & AoE Hex from his level 25 talent.

* Casting Bramble Maze on top of Meepo guarantees a root, as it is nearly impossible to leave the thorns with all of Meepo's clones.
* Terrorize and Cursed Crown offer great disables against the grouped Meepos and can prevent them from using Poof to escape.

* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.

* Windrun does not protect Windranger from Cursed Crown's stun or Dark Willow's magical nukes.
* Focus Fire cannot target Dark Willow in Shadow Realm and will be interrupted if targeted earlier, wasting the ultimate.
Additional:
* Windrun does not protect Windranger from Cursed Crown stun or Dark Willow's magical nukes.
* Focus Fire cannot target Dark Willow in Shadow Realm and will be interrupted if targeted earlier, wasting the ultimate.

* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.

* Bramble Maze will very likely catch Marci midair, disabling Marci's chasing/fleeing ability.
* Shadow Realm prevents Marci from bursting Willow down since she relies on physical attacks and unit target spells. With Aghanim's Scepter, Willow can hit Marci while Marci can't hit Willow.
* Bedlam and Eul's Scepter of Divinity allows Willow to manfight if Marci initiates with Rebound.
* Terrorize and Cursed Crown combo can waste Marci's ultimate for almost half of its duration.

* Long range disables are really effective against dangerous area controllers and channeling Heroes, like Enigma, Faceless Void or Crystal Maiden, as it may cancel them or prevent enemies from doing further damage while keeping Lion in a relatively safe distance in the warzone.

* Terrorize forces Faceless Void out of Chronosphere.

* Mana Drain has an fair long range and low cooldown. It can easily deplete most heroes of their entire mana pools, especially those with smaller mana pools such as Tiny or Spirit Breaker.

* Bramble Maze stops Charge of Darkness in its tracks. Its very long duration means it can be used as an obstacle to block off an incoming Spirit Break during teamfights.
* Shadow Realm and Bedlam can be activated when Dark Willow sees Charge of Darkness coming, preventing Spirit Breaker from using Nether Strike after the initial stun.

* Terrorize, Bedlam and Cursed Crown can damage Muerta through Pierce the Veil.
* Even if Muerta has Black King Bar and Pierce the Veil active, Dark Willow can still use Shadow Realm to protect herself against the Pierce the Veil's high damage, as Muerta cannot attack her for it's duration.

* Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Lion has used all his crowd control before entering a fight. His direct magic burst also makes Brewmaster's Drunken Brawler worthless versus Lion.

* Sniper lacks any protection against Lion's disables early in the game.
* Lion's Earth Spike and Finger of Death may roughly hit Sniper at the latter increased attack range, making it possible to gank and to disable him from afar in clashes.
* Finger of Death is incredibly dangerous for Sniper as it may shred him away from fights, or in the worst scenario, cause his death.

* Terrorize forces Monkey King out of Wukong's Command.

* All of Lion's abilities are active making Demonic Purge break from Aghanim's Scepter useless.
* Hex and Mana Drain can make quick work of whatever illusions you're creating, especially when he acquires his Talents at level 20 and 25.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Earth Spike or Finger of Death with Aghanim's Scepter for the enemy.

* Dark Willow's burst damage and stun prevents Troll Warlord from approaching her until he has Black King Bar.
* Troll Warlord's lack of burst damage makes it hard for him to kill Dark Willow before she slips into Shadow Realm.

* Lion's instant cast point shuts down his initiation and buys time for his allies to catch up.
* Void Spirit has to be cautious when fighting, as he has no protection against Finger of Death. If caught out in a stun, the high magic damage could end him quickly.

* Weaver's exceptional ability to elude and survive through clashes and ganks is hard countered by Lion in every aspect.
* Weaver is very mana dependent and has a rather small mana pool in the beginning of the game, of which Mana Drain can deplete and lessen his early game presence.
* Earth Spike followed by Finger of Death in the huge majority of the time is enough to kill Weaver.
* Earth Spike can be point targeted to hit through Shukuchi.
* Hex's has a fair long duration, by which Weaver will not be able to deal damage, or even survive a coordinated attack, and it is single target, of which cannot be dodged.
* Mana Drain easily breaks Linken's Sphere. Its low cooldown allows Lion to infinitely break it whenever it recharges.
* Earth Spike and Hex when paired for the longer lengths of disables may diminish Time Lapse efficiency, possibly causing Weaver to not undo as much damage as he would.

* Mana Drain depletes Necrophos's mana pool, preventing him from using his abilities.
* Finger of Death deals high magical damage, which becomes amplified by Ghost Shroud.

* Hex and Earth Spike can hold Clinkz down, giving him no chance to use Black King Bar or Skeleton Walk.
* Finger of Death quickly kills Clinkz due to his low health.

* Hex and Mana Drain can be used to immediately destroy Spectre's illusion when she Haunts. A fast fingered Lion can protect himself and a teammate.
* Hex and Earth Spike are good lockdown spells to control and kill Spectre, especially if she doesn't buy defensive items like Linken's Sphere and Black King Bar.
* Finger of Death can be used to burst down Spectre when she is low on life as she has very poor magic resistance.

* Lion has two low cast point disables (Hex and Earth Spike) to control Ursa before he buys a Black King Bar.
* Hex is one of the few abilities that cannot be dispelled even with an Aghanim's Scepter upgraded Enrage.
* Lion can control Ursa's low mana pool via Mana Drain.

* Medusa lacks mobility or escape mechanisms. Earth Spike and Hex can neutralize her strong damage potential and allow for Lion's team to focus her down.
* Mana Drain is a perfect ability to weaken Medusa's durability as it can quickly drain her Mana Shield, making her far less tanky. Mana Drain can also be used to restore mana of Lion's allies, which can nullify the mana steal from Mystic Snake.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.

* Bramble Maze greatly hinders Bloodseeker's ability to run around in teamfights and pick off dying allies.
* Shadow Realm prevents Bloodseeker from attacking dark Willow, allowing her to safely teleport away.

* Mana Drain rapidly saps Morphling's already low mana pool, making him unable to use Waveform or Adaptive Strike. Additionally, Hex prevents these abilities as well.
* An Earth Spike and Finger of Death combo can burst an unwary Morphling down if he has his strength fully shifted to agility.

* With a lot of disables with good range, he might cancel your Echo Stomp.
* Mana Drain can be used to drain Elder Titan's already low mana pool.

* Heroes with forced movement abilities or non-interrupting forced movement, such as Lion, Drow Ranger, Magnus, Mars, as they can cancel blast-off mid air, removing his ability to initiate or escape.

* Lion may upgrade Mana Drain, Hex and Finger of Death through Talent Tree and Aghanim's itens to make them affect secondary targets or turn them into AoE abilities. This can make things difficult for heroes like Phantom Lancer, Naga Siren and Terrorblade, who rely on illusion armies.

* Heroes with channeling spells, for Chen has no disables on his own, hates buying disabling items and his creeps are often not fast enough to cancel them: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.

* Lion may upgrade Mana Drain, Hex and Finger of Death through Talent Tree and Aghanim's itens to make them affect secondary targets or turn them into AoE abilities. This can make things difficult for heroes like Phantom Lancer, Naga Siren and Terrorblade, who rely on illusion armies.

Additional:
* Both Hex and Mana Drain destroy Naga Siren's illusions in an instant, making it hard for her to teamfight or push against a team with Lion. If Lion chooses the AoE effect talent for Hex or the shard for multi-target Mana Drain, it can negate her pushing potential entirely.
* Earth Spike is an AoE disable with good damage. If used well, it can help distinguish the true Naga Siren by the damage they take (illusions take more damage).

* Heroes with nukes: Bane, Lich, Lion, Skywrath Mage

Additional:
* Enchantress is very fragile without any form of magic resistance, allowing Lion to easily burst her down.
* Nature's Attendants is a slow heal, making not as much effective against Lion's burst as it could be.
* Her raw movement speed is a fair escape/mobility mechanism, which may allow her to avoid a blindly cast Earth Spike, but does nothing against the rest of Lion's abilities, since they are single target and can't miss.
* Since Lion's damage comes mostly from his skills, Untouchable does nothing to mitigate it.

* Heroes with powerful rooting abilities will disable most of Pangolier's skills, a bonus point if it pierces spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren

* Heroes that can drain mana negatively affect Viper's ability to use Poison Attack, Nethertoxin and Viper Strike: Lion, Anti-Mage

* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Long range disables are really effective against dangerous area controllers and channeling Heroes, like Enigma, Faceless Void or Crystal Maiden, as it may cancel them or prevent enemies from doing further damage while keeping Lion in a relatively safe distance in the warzone.

* Lion may upgrade Mana Drain, Hex and Finger of Death through Talent Tree and Aghanim's itens to make them affect secondary targets or turn them into AoE abilities. This can make things difficult for heroes like Phantom Lancer, Naga Siren and Terrorblade, who rely on illusion armies.

* Heroes with high magical burst damage will kill Gyrocopter before he gets to do much: Lina, Lion, Zeus

* High priority targets like Queen of Pain, Drow Ranger, Ember Spirit can't get caught out from Lion's long range disables, making it harder to them fulfill their roles, and making it easy to target them.

* Finger of Death can instantly shred many targets, especially fragile Heroes like Keeper of the Light, Ancient Apparition or Bounty Hunter.

* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Luna, Puck, Slark, Nyx Assassin, etc.

* Finger of Death can instantly shred many targets, especially fragile Heroes like Keeper of the Light, Ancient Apparition or Bounty Hunter.

* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:Lion, Crystal Maiden ,Venomancer etc.

* Heroes with high burst damage through their physical attacks or spells can kill Dazzle or his allies before he has a chance to use Shallow Grave. (Lina, Lion, etc.)

* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin.

* Hex abilities can cancel the channelling of Fiend's Grip : Lion, Shadow Shaman, Dazzle from Aghanim's Shard with upgraded Poison Touch.

* Heroes with high magical burst can easily kill Huskar when he is at low health: Lion, Lina, Skywrath Mage

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Despite her high mobility, Hex or Earth Spike can lock Phantom Assassin down, make her vulnerable and mitigate her damage output.
* Lion relies entirely on his abilities to be effective, rendering Phatnom Assassin's high evasion through ineffective against him. And Phantom Assassin's low health pool makes her vulnerable to Lion's magical burst without Black King Bar.

* Wraith King has a very low mana pool and is extremely dependant on it to cast his high mana cost abilities, so Mana Drain will make him struggle way too hard, even not being able to active his passive ability Reincarnation, forcing the Wraith King to buy Aghanim's Shard as soon as possible.
* Althought Wraith King may not be as fragile to struggle against Lion's damage, it's much easier to disable and harass him, as Wraith King doesn't have any mobility at all, his only gap closer being Wraithfire Blast which costs too much mana for his mana pool, and may only affect one target.
Additional:
* While not being able to confront Wraith King by himself, Lion's Mana Drain helps in draining Wraith King's mana, preventing him from reincarnating unless he has his Aghanim's Shard.
* Lion's Earth Spike and Hex provide decent lockdown against Wraith King as well, preventing the latter from benefiting from Vampiric Spirit bonuses.

* Mana Drain has an fair long range and low cooldown. It can easily deplete most heroes of their entire mana pools, especially those with smaller mana pools such as Tiny or Spirit Breaker.

Additional:
* Lion can continuously Mana Drain Tiny in the early game, depleting his small mana pool for his abilities.

* Sven is very vulnerable to chain stun such as Lion, Shadow Shaman or Magnus.

* Lion possesses two strong disables in Earth Spike and Hex and heavy magic burst with Finger of Death which help lock him down and prevent him from escaping with Activate Fire Remnant. When getting his Blink Dagger Lion can punish Ember Spirit's overextension immediately, or initiate a fight on him with disables.

* Heroes that can kill Death Prophet with nukes can prevent her from using Exorcism to its full duration or using it at all: Lina, Lion, Puck, Morphling.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes with long or multiple disables will prevent Legion Commander from winning Duels: Shadow Shaman, Lion

* Drow Ranger has a very low health pool, allowing Lion to burst her down.
* Lack of any innate escape mechanism makes her an easy target for Lion's disables.
* Early on she can't deal as much damage to be life threatning. Her Gust is her best weapon against Lion.