* Heroes with heavy magical nukes will take advantage of Slark's poor HP or force him to use Shadow Dance early: Lina, Lion, Zeus

* Heroes with magic immune abilities can negate most of Visage's attacks like Pangolier and Lifestealer.

* Lion may upgrade Mana Drain, Hex and Finger of Death through Talent Tree and Aghanim's itens to make them affect secondary targets or turn them into AoE abilities. This can make things difficult for heroes like Phantom Lancer, Naga Siren and Terrorblade, who rely on illusion armies.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Finger of Death can instantly shred many targets, especially fragile Heroes like Keeper of the Light, Ancient Apparition or Bounty Hunter.

* Long range disables are really effective against dangerous area controllers and channeling Heroes, like Enigma, Faceless Void or Crystal Maiden, as it may cancel them or prevent enemies from doing further damage while keeping Lion in a relatively safe distance in the warzone.

* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.

* Backline supports (Lion,Crystal Maiden) can keep Puck pinned long enough for a kill.

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar, and Tusk have spells which allow them to easily escape Dream Coil.

* Sniper lacks any protection against Lion's disables early in the game.
* Lion's Earth Spike and Finger of Death may roughly hit Sniper at the latter increased attack range, making it possible to gank and to disable him from afar in clashes.
* Finger of Death is incredibly dangerous for Sniper as it may shred him away from fights, or in the worst scenario, cause his death.

* Lifestealer can close the distance to Sniper by using Infest on a fast or durable creep to tank Sniper's damage.
* Open Wounds and Ghoul Frenzy will reduce Sniper's mobility heavily, and Rage's movement speed bonus helps in closing the gap to Sniper. It also protects him from Assassinate and Shrapnel.
* Infest can dodge an incoming Assassinate.

* Hex and Mana Drain can be used to immediately destroy Spectre's illusion when she Haunts. A fast fingered Lion can protect himself and a teammate.
* Hex and Earth Spike are good lockdown spells to control and kill Spectre, especially if she doesn't buy defensive items like Linken's Sphere and Black King Bar.
* Finger of Death can be used to burst down Spectre when she is low on life as she has very poor magic resistance.

* Feast deals damage and heals lifestealer based on the target max health. Because Spectre often emphasises on building stat items to increase her HP pool, lifestealer can deal a lot of damage to her and heal himself at the same time.
* Ghoul Frenzy slows target, which is bad for Spectre if she does not have Spectral Dagger ready.
* Spectre cannot response to infest if lifestealer choose to stay inside his high mobility allies to approach the backline. Rage's bonus movement speed and spell immunity make it even more frustrating.

* Heroes with forced movement abilities or non-interrupting forced movement, such as Lion, Drow Ranger, Magnus, Mars, as they can cancel blast-off mid air, removing his ability to initiate or escape.

* Rage protects Lifestealer from all of Techies' abilities. Reactive Tazer's disarm will also not work on Lifestealer under Rage.
* Rage can also be used to trigger Techies' Proximity Mines safely.
Additional:
* Lifestealer's Rage lets him clear Proximity Mines without taking damage, and allows him to hit heroes whom Techies has used Reactive Tazer on.

* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:Lion, Crystal Maiden ,Venomancer etc.

* Being a strength hero with a high strength gain means Feast can give her a hard time,especially later in the game.
* However,Starbreaker's physical damage can control him in the laning phase.

* Lion's instant cast point shuts down his initiation and buys time for his allies to catch up.
* Void Spirit has to be cautious when fighting, as he has no protection against Finger of Death. If caught out in a stun, the high magic damage could end him quickly.

* Heroes with burst damage of their own won't be afraid to go toe to toe with Void Spirit, like Ursa, Lifestealer, or Axe.

* Ranged heroes that can easily harass Axe: Drow Ranger, Sniper, Lion.

* Feast makes it impossible to for Lifestealer to be culled with Culling Blade and also deals high damage to Axe due to his naturally high health. However, Rage can still be pierced by Berserker's Call and Counter Helix.

* Heroes that can drain mana negatively affect Viper's ability to use Poison Attack, Nethertoxin and Viper Strike: Lion, Anti-Mage

* Rage ignores all of Viper's magical damage, although Viper Strike can pierce spell immunity and slows him down.
* Feast and Open Wounds from Aghanim's Shard can be combined to heal through Viper's physical damage.
* Aghanim's Scepter upgraded Infest can be used to disarm Viper, preventing him from using Poison Attack on Lifestealer's allies.

* Heroes with high magical burst damage will kill Gyrocopter before he gets to do much: Lina, Lion, Zeus

* Rage ignores all of Gyrocopter's magical attacks.
* Feast helps Lifestealer out-damage Gyrocopter at close range.

* Heroes that can keep Marci for a long time in one place so she can't pursue her targets, like Bane, Lion, Shadow Shaman, Invoker, Disruptor and Kunkka.

* Lifestealer's Rage renders him immune to all of Marci's disables and magic damage for a good duration.
* His passive Feast deals bonus damage based on the enemy's max health and heals for the same amount. As a tanky Strength hero, Marci's own strength will be her undoing as well.

* Heroes with high magical burst can easily kill Huskar when he is at low health: Lion, Lina, Skywrath Mage

* Rage renders Lifestealer immune to the damage from Burning Spears.
* Feast makes Lifestealer one of few heroes that can outlast Huskar in a one-on-one fight.

* Heroes with channeling spells, for Chen has no disables on his own, hates buying disabling items and his creeps are often not fast enough to cancel them: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.

* Rage gives Lifestealer spell immunity, Chen and his converted creeps have little to no ways of fighting back against Lifestealer whenever he activates it.
* Feast allows Lifestealer to recover himself by damaging Chen's creeps.
* Chen has no escape mechanisms, so he will often be unable to escape from slows applied with Ghoul Frenzy.
* Open Wounds from Aghanim's Shard can severely slow down Chen, and allow Lifestealer and his team to heal themselves by attacking Chen. Open Wounds can also fester and spread if Chen takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest allows Lifestealer to infest into one of Chen's converted creeps and take control of it, which allows Lifestealer to either escape from Chen or surprise him. Aghanim's Scepter upgraded Infest can disarm Chen and allow Lifestealer to attack Chen from within, even if Chen is spell immune.

* Lion can continuously Mana Drain Tiny in the early game, depleting his small mana pool for his abilities.

* Feast will deal a enormous amount of damage because of Tiny's huge health pool.
* Rage protects Lifestealer from Tiny's magical burst damage.

* Long range disables are really effective against dangerous area controllers and channeling Heroes, like Enigma, Faceless Void or Crystal Maiden, as it may cancel them or prevent enemies from doing further damage while keeping Lion in a relatively safe distance in the warzone.

* Juggernaut and Lifestealer have abilities (Blade Fury and Rage respectively) that prevent Crystal Maiden from using her spells on them in the early game, before Black King Bar and other magical reduction is even an issue.

Additional:
* Crystal Maiden is an ideal target for Lifestealer due to her poor mobility and low health pool. Lifestealer can usually catch up to her simply by casting Rage, as none of her abilities pierce through magic immunity. Freezing Field can potentially make her even more vulnerable to Lifestealer while under Rage as she is even more immobile while channeling it.
* Lifestealer commonly buys Abyssal Blade, which allows him to cancel Freezing Field, even if Crystal Maiden is spell immune.
* Alternatively, Aghanim's Scepter upgraded Infest combined with Abyssal Blade and with items that provide attack speed which Lifestealer commonly buys allow him to to cancel Freezing Field from within the Crystal Maiden.

* Finger of Death can instantly shred many targets, especially fragile Heroes like Keeper of the Light, Ancient Apparition or Bounty Hunter.

* Heroes who have most or all their abilities (damage or disable) unable to pierce spell immunity: Keeper of the Light, Lina, Lion, Zeus.

Additional:
* Rage allows him to be immune to all of Ezalor's abilities. Also, the increased movement speed combined with the slow from Ghoul Frenzy and the squishy nature of Ezalor allows Lifestealer to take him down very quickly.

* Finger of Death can instantly shred many targets, especially fragile Heroes like Keeper of the Light, Ancient Apparition or Bounty Hunter.

* Lifestealer with Rage and Infest
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Feast deals damage and heals Lifestealer based on the target's maximum HP, which is greatly effective against naturally high HP heroes such as Doom.
* Rage allows Lifestealer to become spell immune to negate the magical damage of Infernal Blade and Scorched Earth.
* Doom has no effective means of escape from Open Wounds. This is particularly devastating in lane, where Doom may have to play a much more passive, conservative play style as a result.

* Hex greatly reduces Timbersaw's mobility.
* In addition, Lion can follow up with his Earth Spike and Mana Drain combo, preventing Timbersaw to escape with Timber Chain. And he can finish Timbersaw off with Finger of Death if the latter's HP is low enough.

* Rage, acting as a pseudo-Black King Bar, completely negates Mars' initiation if used in time.
* Feast does damage and heals based on max health, perfect against high-health strength heroes like Mars.
* Infest allows Lifestealer to potentially save allies from Mars' initiation with a quick burst of extra health.

* With Feast and Rage, Lifestealer is nearly impossible for Clockwerk to bring down, and is the last hero Clockwerk wants to be trapped with in Power Cogs.

* Rage protects Lifestealer from all of Dark Willow's abilities.
Additional:
* Rage protects and dispels all of Dark Willow's abilities.

* Drow Ranger has a very low health pool, allowing Lion to burst her down.
* Lack of any innate escape mechanism makes her an easy target for Lion's disables.
* Early on she can't deal as much damage to be life threatning. Her Gust is her best weapon against Lion.

* The lifesteal of Feast scales accordingly to the max health of its target, which is effective against Pudge due to his high health and further health granted by stacks of Flesh Heap.
* Lifestealer can activate Rage to be spell immune, making Rot deal no damage.
* Pudge's plentiful health makes him an ideal target for Lifestealer's Aghanim's Shard ability, Open Wounds.

* Feast is good against high health strength heroes such as Alchemist.
* Rage allows Lifestealer to not be targetable by Unstable Concoction, possibly making Alchemist stun himself.

* Rage protects Lifestealer from all of Lina's abilities (except an upgraded Laguna Blade).
* Open Wounds is great to keep Lina in place because she has no abilities to help her escape.

* Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Lion has used all his crowd control before entering a fight. His direct magic burst also makes Brewmaster's Drunken Brawler worthless versus Lion.

* Rage protects Lifestealer from all of Invoker's spells (except for Sun Strike).
Additional:
* Rage grants immunity from Invoker's spells and can dispel most of the disables such as the armor loss from Forge Spirit and the constant stuns of Cold Snap.

* Lifestealer's Rage makes him immune to all of Ogre's magical debuffs and also dispels them.
* Ogre's high health pool makes him an ideal target for Feast.
Additional:
* Ogre Magi has nothing against Rage and his high health pool amplifies Feast.

* Lifestealer is able to endure Undying, especially in the laning phase, where Undying is strongest. Feast can offset Decay's strength steal for its percentage lifesteal. Rage delays Undying from stealing strength and can help Lifestealer destroy Undying's Tombstone uninterrupted. As well, none of Undying's abilities pierce magic immunity.

* Centaur Warrunner's active abilities cannot pierce magic immunity. Hoof Stomp's slow wind up can also be anticipated and negated with Rage.
* Lifestealer can offset Retaliate's damage return simply with Feast. Centaur's high strength gain and therefore big health pool makes him an ideal target to Feast on, especially in the late-game.
Additional:
* Feast is an effective tool against Centaur Warrunner, who generally has high health and low armor, and compensates the reflected damage of Retaliate.
* If activated, Rage can protect Lifestealer from Hoof Stomp, Double Edge, and Stampede.

* Rage prevents Earthshaker from damaging and stunning Lifestealer.
* Feast is very effective against Earthshaker, because of him being a strength hero, allowing Lifestealer to heavily harass and kill him.
* Open Wounds prevents Earthshaker from escaping after he initiated.
* Infest gives Lifestealer an easy way to escape should he get caught out by Earthshaker. And against carry Earthshaker, Aghanim's Scepter upgraded Infest can be used to disarm Earthshaker and attack him from within, rendering him unable to attack with Enchant Totem.

* Mana Drain depletes Nercophos's mana pool, preventing him from using his abilities.
* Finger of Death deals high magical damage, which becomes amplified by Ghost Shroud.

* Like with Juggernaut's Blade Fury, Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if Vendetta is on cooldown. Nyx Assassin cannot counter Rage with Spiked Carapace because Rage gives Lifestealer spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
* Open Wounds from Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with Dust of Appearance or a Gem of True Sight. And similarly to Juggernaut's Omnislash and Swiftslash from Aghanim's Scepter, Aghanim's Scepter upgraded Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. and Nyx Assassin cannot counter this with Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
* Like with Juggernaut, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.

* Rage is very useful against Zeus, as it negates magic damage and provides spell immunity. In addition, the increased attack speed can tear Zeus apart in combination with Open Wounds.
* Lifestealer can avoid Thundergod's Wrath with Infest.

* With a lot of disables with good range, he might cancel your Echo Stomp.
* Mana Drain can be used to drain Elder Titan's already low mana pool.

* Wraith King has a very low mana pool and is extremely dependant on it to cast his high mana cost abilities, so Mana Drain will make him struggle way too hard, even not being able to active his passive ability Reincarnation, forcing the Wraith King to buy Aghanim's Shard as soon as possible.
* Althought Wraith King may not be as fragile to struggle against Lion's damage, it's much easier to disable and harass him, as Wraith King doesn't have any mobility at all, his only gap closer being Wraithfire Blast which costs too much mana for his mana pool, and may only affect one target.
Additional:
* While not being able to confront Wraith King by himself, Lion's Mana Drain helps in draining Wraith King's mana, preventing him from reincarnating unless he has his Aghanim's Shard.
* Lion's Earth Spike and Hex provide decent lockdown against Wraith King as well, preventing the latter from benefiting from Vampiric Spirit bonuses.

* If Meepo ganks Lion with Poof and Earthbind, he will be an easy target for Earth Spike & AoE Hex from his level 25 talent.

* Lifestealer is not affected by Earthbind or Poof during Rage, making him a difficult target to work around.

* High priority targets like Queen of Pain, Drow Ranger, Ember Spirit can't get caught out from Lion's long range disables, making it harder to them fulfill their roles, and making it easy to target them.

Additional:
* Lion possesses two strong disables in Earth Spike and Hex and heavy magic burst with Finger of Death which help lock him down and prevent him from escaping with Activate Fire Remnant. When getting his Blink Dagger Lion can punish Ember Spirit's overextension immediately, or initiate a fight on him with disables.

* Despite her high mobility, Hex or Earth Spike can lock Phantom Assassin down, make her vulnerable and mitigate her damage output.
* Although she has high evasion through Blur, Phantom Assassin has a rather low health pool, making her weak to Lion's magical burst.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Sven is very vulnerable to chain stun such as Lion, Shadow Shaman or Magnus.

* In general, heroes with spell immunity abilities won't be caught inside by Pit of Malice: Juggernaut, Lifestealer.

* Heroes that can kill Death Prophet with nukes can prevent her from using Exorcism to its full duration or using it at all: Lina, Lion, Puck, Morphling.

* Lion has two low cast point disables (Hex and Earth Spike) to control Ursa before he buys a Black King Bar.
* Hex is one of the few abilities that cannot be dispelled even with an Aghanim's Scepter upgraded Enrage.
* Lion can control Ursa's low mana pool via Mana Drain.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* High priority targets like Queen of Pain, Drow Ranger, Ember Spirit can't get caught out from Lion's long range disables, making it harder to them fulfill their roles, and making it easy to target them.

* Skywrath's pitiful defences also make him easy meat to heroes with high burst like Juggernaut, Lion, or Phantom Assassin, the latter occasionally downing a support Skywrath in a single Stifling Dagger.

* Heroes with spell immunity-granting spells will render Phoenix useless against them, as Phoenix has almost no spell immunity-piercing ability, other than the stun at the end of Supernova: Lifestealer, Juggernaut.

* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin.

* Mana Drain has an fair long range and low cooldown. It can easily deplete most heroes of their entire mana pools, especially those with smaller mana pools such as Tiny or Spirit Breaker.

* Heroes with high burst damage through their physical attacks or spells can kill Dazzle or his allies before he has a chance to use Shallow Grave. (Lina, Lion, etc.)

* Heroes with built-in spell immunity can become immune to all of Outworld Destroyer's spells: Lifestealer's Rage and Juggernaut's Blade Fury.

* Heroes with good escape mechanisms are a nuisance to deal with in the early phase of the game: Slark, Lifestealer, Morphling

* All of Lion's abilities are active making Demonic Purge break from Aghanim's Scepter useless.
* Hex and Mana Drain can make quick work of whatever illusions you're creating, especially when he acquires his Talents at level 20 and 25.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Earth Spike or Finger of Death with Aghanim's Scepter for the enemy.

* Lifestealer can activate Rage to become spell immune, making Pierce the veil do no damage and preventing Dead Shot from fearing or doing damage.
* Lifestealer can use Infest to avoid Muerta's Gunslinger shots, Dead Shot's fear and surprise Muerta. Aghanim's Scepter upgraded Infest can be used to disarm Muerta while she has Pierce the Veil and even through Black King Bar.
* However, Lifestealer has no way of hurting Muerta through Pierce the Veil outside of Infest, Lifestealer's only source of dealing magical damage.

* Leshrac's high magic damage is ignored by Rage.
* Lifestealer can get in Leshrac's face with Rage and mitigate any other damage taken by Leshrac with Open Wounds.

* Rage can protect Lifestealer from most of the Silencer's abilities with the exception of Global Silence, as it will still silence if cast while the target is magic immune. However, it will not work if Lifestealer is infesting a unit.
* Silencer is vulnerable to Open Wounds due to his lack of an innate escape.
* Against a carry Silencer, Aghanim's Scepter upgraded Infest can disarm him and allow Lifestealer to attack Silencer from within, even if Silencer is spell immune.
Additional:
* Rage can protect Lifestealer from most of the Silencer's abilities with the exception of Global Silence.
* If Lifestealer can Infest himself on any unit, he can literally avoid being affected by Global Silence.
* Against a carry Silencer, Aghanim's Scepter upgraded Infest can disarm him and allow Lifestealer to attack Silencer from within, even if Silencer is spell immune.
* Open Wounds from Aghanim's Shard can severely slow down Silencer, and allow Lifestealer and his team to heal themselves by attacking Silencer.

* Rage will dispel Laser's blind and turns him spell immune for the duration so Tinker cannot damage him.
* Feast will quickly bring down Tinker due to being so fragile.
Additional:
* Lifestealer's Rage makes him immune to all of Tinker's damage and debuffs.
* Lifestealer can infest a mobile ally (teams usually pick one against Tinker), which may ensure that Tinker will die if he is caught.

* Rage negates Kunkka's X Marks the Spot.
* As a strength hero with high strength gain and very little armor, as well as low agility gain, Kunkka is vulnerable to Lifestealer's Feast and Open Wounds.

* Lion may upgrade Mana Drain, Hex and Finger of Death through Talent Tree and Aghanim's itens to make them affect secondary targets or turn them into AoE abilities. This can make things difficult for heroes like Phantom Lancer, Naga Siren and Terrorblade, who rely on illusion armies.

* With Aghanim's Scepter upgraded Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.

* Long range disables are really effective against dangerous area controllers and channeling Heroes, like Enigma, Faceless Void or Crystal Maiden, as it may cancel them or prevent enemies from doing further damage while keeping Lion in a relatively safe distance in the warzone.

* Enigma lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Enigma finishes his initiation: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.

* Enchantress is very fragile without any form of magic resistance, allowing Lion to easily burst her down.
* Nature's Attendants is a slow heal, making not as much effective against Lion's burst as it could be.
* Her raw movement speed is a fair escape/mobility mechanism, which may allow her to avoid a blindly cast Earth Spike, but does nothing against the rest of Lion's abilities, since they are single target and can't miss.
* Since Lion's damage comes mostly from his skills, Untouchable does nothing to mitigate it.

* Medusa lacks mobility or escape mechanisms. Earth Spike and Hex can neutralize her strong damage potential and allow for Lion's team to focus her down.
* In addition to easily breaking her commonly bought Linken's Sphere with its low cooldown, Mana Drain can quickly drain her Mana Shield, making her far less tanky.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.

* Mana Drain rapidly saps Morphling's already low mana pool, making him unable to use Waveform or Adaptive Strike. Additionally, Hex prevents these abilities as well.
* An Earth Spike and Finger of Death combo can burst an unwary Morphling down if he has his strength fully shifted to agility.

* Heroes with mana burn: Nyx Assassin, Invoker, Outworld Destroyer, Pugna, Lion

* Rage can be used to escape from a Glimpse and to move out of Kinetic Field.
* Infest allows Lifestealer to dodge Glimpse.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes with long or multiple disables will prevent Legion Commander from winning Duels: Shadow Shaman, Lion

* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Lion's Mana Drain is a headache for Bristleback to deal with during the laning stage, as it denies him the ability to get last hits with Quill Spray.

* Weaver's exceptional ability to elude and survive through clashes and ganks is hard countered by Lion in every aspect.
* Weaver is very mana dependent and has a rather small mana pool in the beginning of the game, of which Mana Drain can deplete and lessen his early game presence.
* Earth Spike followed by Finger of Death in the huge majority of the time is enough to kill Weaver.
* Earth Spike can be point targeted to hit through Shukuchi.
* Hex's has a fair long duration, by which Weaver will not be able to deal damage, or even survive a coordinated attack, and it is single target, of which cannot be dodged.
* Mana Drain easily breaks Linken's Sphere. Its low cooldown allows Lion to infinitely break it whenever it recharges.
* Earth Spike and Hex when paired for the longer lengths of disables may diminish Time Lapse efficiency, possibly causing Weaver to not undo as much damage as he would.

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* Lifestealer's Rage negates Sand King's spells which do magical damage.

* Lion may upgrade Mana Drain, Hex and Finger of Death through Talent Tree and Aghanim's itens to make them affect secondary targets or turn them into AoE abilities. This can make things difficult for heroes like Phantom Lancer, Naga Siren and Terrorblade, who rely on illusion armies.

Additional:
* Both Hex and Mana Drain destroy Naga Siren's illusions in an instant, making it hard for her to teamfight or push against a team with Lion. If Lion chooses the AoE effect talent for Hex or the shard for multi-target Mana Drain, it can negate her pushing potential entirely.
* Earth Spike is an AoE disable with good damage. If used well, it can help distinguish the true Naga Siren by the damage they take (illusions take more damage).

* Hex and Earth Spike can hold Clinkz down, giving him no chance to use Black King Bar or Skeleton Walk.
* Finger of Death quickly kills Clinkz due to his low health.

* Rage grants Lifestealer immunity to all of Jakiro's spells. Note: magic resistance will not dispel the attack speed slow effects from Dual Breath and Liquid Fire.

* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Lion, Silencer, Shadow Shaman, Grimstroke, Witch Doctor, Riki, Faceless Void, Skywrath Mage, Puck.

* Heroes with long disables, like Lion, Night Stalker, or Legion Commander, can prevent Oracle from using spells or items.