* Lone Druid and his Spirit Bear lack mobility, and are easy overwhelmed after being slowed by Diffusal Blade.
* Savage Roar is useless since Phantom Lancer can return to fight him again with his Phantom Rush.

* Phantom Lancer's many illusions will easily destroy Tombstone, provided he has sufficient farm.
* He also has no ways of dealing with the illusions, since Decay doesn't steal strength from illusions.

* Ghost Shroud can be use both offensively to slow Lone Druid or Defensively to prevent Lone Druid and The Spirit Bear from attacking him.
* Heartstopper aura burns the Spirit bear High HP over time. Additionally, it can deal decent damage to Lone Druid during his True Form.

* Necrophos is a dangerous opponent to go against with. Regardless of how much strength Undying has gained from Decay, Necrophos can finish off Undying with Reaper's Scythe once Undying's HP falls below a certain threshold.
* Heartstopper Aura will do more damage to Undying if he gained strength from Decay, as it does damage based on a hero's maximum health.

* Firestorm's percentage damage can quickly demolish the Spirit Bear's high HP
* Pit of Malice will allow allies to easily kite Lone Druid due to his low mobility

* In general, melee heroes without blink mechanisms or spell immunity will have a hard time positioning against Pit of Malice: Sven, Tiny, Wraith King, Dragon Knight, Meepo, Doom, Bounty Hunter, Dark Seer, Undying, Alchemist, Legion Commander.

* Reality Rift lets Chaos Knight bypass the Spirit Bear and jump onto Lone Druid.
* The Spirit Bear's lack of scaling means it dies quickly to Chaos Knight during the late-game.

* Chaos Knight's multiple illusions from Phantasm can destroy Undying, as Soul Rip can't offset the damage from the high amount of damage from his illusions.

* Timbersaw: Lone Druid will have a hard time dealing with Timbersaw due to his tankiness and high Armor from Reactive Armor

* Reactive Armor makes Timbersaw very effective against heroes that control a lot of units, such as Broodmother, Lycan and Undying.

* Laser blinds Lone Druid, making his attacks miss.

* Tombstone's zombies rarely inhibit Anti-Mage, as he can either Blink away or onto the Tombstone and destroy it.

* Brewmaster can make the Spirit Bear a much smaller threat with Cinder Brew.
* Cyclone removes the bear from a fight so that his team can easily focus on the hero.
* While most heroes would be worn down by a Spirit Bear Radiance in the time it takes to kill Lone Druid, Brewmaster is protected in Primal Split.

* Unless Lone Druid purchases a Black King Bar for his Spirit Bear, Ensnare will easily kite the Bear.
* Song of the Siren allows Naga Siren and her team to completely bypass the Spirit Bear and hunt for the Druid himself when starting a fight.
* Lone Druid's lack of innate AoE capabilities mean that Naga Siren's illusions have no problem against him.

* Zombies summoned from Tombstone will amplify the damage of Echo Slam due to them increasing the echo damage.

* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.

* Chain Frost can deliver high amounts of damage to Lone itself and his bear if they do not separate fast from each other.
Additional:
* Chain Frost will bounce between Lone Druid and his bear, forcing them to separate or suffer high amounts of damage.

* Flak Cannon rips through Tombstone's zombies.
Additional:
* Flak Cannon enables Gyrocopter to clear the zombies easily.

* Lone druid's bear attacks on Phoenix's Supernova Egg don't increase the hit count. Given that Lone Druid's main hero often doesn't have much farm, the Supernova Egg is less likely to get killed.

* Geminate Attack works on Tombstone, allowing Weaver to kill it quickly.
* Zombies attacking Weaver disappear once he goes invisible with Shukuchi.
* Undying has no way to catch a mobile Weaver.

* Due to Fervor and Battle Trance, Troll Warlord has a significant attack speed, enabling him to crush Tombstone quickly.
* Undying usually stays at the front line with no disables, making him an easy target for Troll Warlord.

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.
Additional:
* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.

* Lifestealer is able to endure Undying, especially in the laning phase, where Undying is strongest. Feast can offset Decay's strength steal for its percentage lifesteal. Rage delays Undying from stealing strength and can help Lifestealer destroy Undying's Tombstone uninterrupted. As well, none of Undying's abilities pierce magic immunity.

* Tidehunter takes close to no damage from Undying's zombies once he maxes out his Kraken Shell, especially if he gets the level 20 Kraken Shell upgrading talent. This might allow him to blink away to safety.

* Tombstone can be stolen to counter-initiate the enemy team in skirmishes.
* Tombstone provides vision over the enemy around, use this to Rubick's advantage for more spells.
* Since Undying is melee and has low attack speed, the tombstone can be hard to taken down by Undying himself.
* Flesh Golem provides Rubick with increased Health pool and a powerful attack modifier.
* Rubick can apply the Flesh Golem debuff much more easily as a ranged hero.
* Decay is a decent damaging ability, making Rubick somewhat tankier in teamfights.
* Soul Rip can be used for extra heal or burst damage.

* Grimstroke's Soulbind will always reliably connect onto both of them if they are close together.

* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.

* Sniper can easily destroy Tombstone from long range.

* Meepo can quickly destroy Tombstone thanks to Divided We Stand.

* Familiars will easily be able to kite heroes with a short range or with low attack speed. For example, Tiny and Undying have a very hard time killing Familiars.

* Death Prophet is able to Silence Undying up to 6 seconds. Besides, due to Undying's high strength during a team fight, Spirit Siphon is a powerful ability against Undying thanks to the percentage health drain.

* Riki: Smoke Screen can prevent Lone Druid from using True Form and Savage Roar, additionally it cause the spirit bear to miss on attacks which reduce the chances of getting rooted from it, with diffusal Blade, he can keep Lone Druid or the Spirit Bear inside the Smoke.

* Clinkz, Sniper, Lone Druid, Troll Warlord, Legion Commander and Wraith King are some of the Heroes that base themselves on attacks with little or no spell power, so they suffer in the grassy hands of Overgrowth.

* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.

* Huskar's huge damage output and attack speed can get rid of Undying and Tombstone quickly.

* Heroes with summons that are destroyed by a fixed number of attacks: Undying's Tombstone, Gyrocopter's Homing Missile, and Zeus's Nimbus.

* Invoker's multiple spells can lock down Undying and disable him from doing much.

* Pugna: Decrepify prevent the Spirit bear from attacking or protect allies from it.

* Heroes that have doubles or clones such as Arc Warden, Meepo or Lone Druid are vulnerable to Muerta's Gunslinger

* Terrorblade can destroy Tombstone with his Conjure Image and Metamorphosis.

* Mystic Flare can be used to effectively ignore the Spirit Bear entirely and burst Lone Druid during the early mid game.
* Concussive Shot and Arcane Bolt will provide vision of Lone Druid allowing for better chase in teamfights before the Spirit Bear can do too much damage.
* Ancient Seal denies the ability to transform into True Form and receive bonus HP from the skill.

* Paralyzing Cask is likely to bounce between him and his bear every single time.
* Lone Druid's lack of mobility makes him vulnerable to Death Ward and Maledict.

* Morphling can ignore Spirit Bear and shorten the distance to Lone Druid with Waveform.
* Morphling can use his nukes to burst Lone Druid down, provided he is not rooted/disabled by Spirit Bear beforehand.