Luna
* Heroes that outrange Luna can be a problem for her: 
Drow Ranger, 
Sniper.
Outworld Destroyer
* As Outworld Destroyer has short cast ranges, a short attack range, and no gap-closing abilities, Sniper can kite and harass Outworld Destroyer in lane with his long range and zone him out in fights. The continuous area damage from 
Shrapnel also prevents Astral-Blink escapes.
* However, in the late game, Outworld Destroyer's massive damage can overwhelm Sniper once he obtains 
Blink Dagger, 
Force Staff etc. to close the gap.
Luna
* 
Demonic Purge takes off Luna's superior mobility, removing the need for chasing her and allowing your team to reposition in team fights or escape when at low HP. If Shadow Demon has Aghanim's Scepter it will also take away glaive bounces and extra damage from Luna's passive. And Luna's commonly items Manta Style and Black King Bar does not work dispell to Demonic Purge
* Luna's illusions created by Disruption are very valuable with their 
Moon Glaives. These will effectively counter her pushing attempts and are painfully effective in team fights.
* Disruption can be used to save an ally from 
Eclipse.
* For the same reasons, Shadow Demon makes a very powerful ally for Luna when they are in the same team.
Additional:
* Demonic Purge takes off Luna's superior mobility, removing the need for chasing her and allowing your team to reposition in team fights or escape when at low HP. If Shadow Demon has Aghanim's Sceptre it will also take away glaive bounces and extra damage from Luna's passive.
* Luna's illusions created by Disruption are very valuable with their Moon Glaives. These will effectively counter her pushing attempts and are painfully effective in team fights.
* Disruption can be used to save an ally from Eclipse.
* For the same reasons, Shadow Demon is a very good ally for Luna when they are in the same team.
Outworld Destroyer
* Shadow Demon's 
Disruption will allow his allies to maneuver around you. It can also be used to protect an ally from your abilities, or Astral Imprisonment - 
Meteor Hammer combo.
* 
Disseminate turns your high damage Arcane Orb and Sanitiy's Eclipse against you and your teammates.
* Scepter upgraded Demonic Purge will break your Essence Flux passive for 7 seconds, preventing you from regaining mana, and severely hindering your damage output.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include 
Spectre, 
Shadow Demon, 
Phantom Lancer, 
Naga Siren, 
Chaos Knight, 
Terrorblade) or bring other units into the fight (such as 
Nature's Prophet, 
Lone Druid, 
Chen, 
Enchantress, 
Meepo and 
Arc Warden).
Luna
* Even though Luna can clear Phantom Lancer's illusions with Moon Glaives, Phantom Lancer can create too many illusions to tank Luna's Eclipse and for Luna to handle overall.
* 
Doppelganger can be used to dodge a number of Lucent Beams during Eclipse.
* Phantom Lancer can chase Luna effectively regardless of her high movement speed thanks to 
Phantom Rush and 
Spirit Lance.
* Luna's low health pool is easily exploited by the sheer damage output from Phantom Lancer's illusions. Additionally, Phantom Lancer can often create more illusions for Luna to handle.
* For the same reasons, Phantom Lancer makes a very powerful ally for Luna when they are in the same team.
Outworld Destroyer
* Doppelganger and 
Juxtapose allow Phantom Lancer to initiate on Outworld Destroyer, and, although Arcane Orb will normally destroy his illusions instantly, Phantom Lancer will spawn too many to deal with without using Sanity's Eclipse.
* Outworld Destroyer has very little AOE ability; His Astral Imprisonment with 
Aghanim's Scepter is his primary AOE, and it does too little damage to eliminate Phantom Lancer's illusions.
Additional:
* Although Outworld Destroyer will typically destroy Phantom Lancer's illusions in one shot, Phantom Lancer spawns too many of them for Outworld Destroyer to deal with. However, be careful about initating on Outworld, as 
Sanity's Eclipse will erase your illusions and deal massive damage to you. He can then follow up with 
Astral Imprisonment and Meteor Hammer.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Luna
* A couple of long-range heroes with excellent laning like 
Mirana, 
Lina, 
Necrophos, 
Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, 
Night Stalker, Drow Ranger, 
Doom .
Luna
* Every hero that can withstand or prevent Eclipse at level 7: 
Juggernaut, 
Riki, 
Clockwerk, Drow Ranger, 
Abaddon, 
Faceless Void, 
Weaver, 
Outworld Destroyer.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .
Luna
* Should Luna choose to buy 
Manta Style, Medusa will be able to kill illusions from them with 
Split Shot and 
Mjollnir, which is a common item on Medusa.
* 
Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with 
Lucent Beam.
* Medusa can survive Eclipse thanks to 
Mana Shield, which can cause Luna to struggle greatly in bursting down Medusa and force her to buy 
Diffusal Blade and it's upgrade 
Disperser.
* Even with 
Black King Bar, Medusa's 
Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Luna
* 
Burrowstrike allows Sand King to escape from Eclipse or to close the gap on Luna and finish her off.
* 
Sand Storm allows Sand King to harass Luna more efficiently than she does with Lucent Beam, as it makes him invisible for it's duration and while in it, rendering him safe from both, Lucent Beam and Eclipse and forcing Luna to buy 
Dust of Appearance more often.
* 
Caustic Finale allows Sand King to deal serious damage to both, Luna and her allies, which is especially hazardous in laning stage as Luna's attack range is short.
* 
Epicenter combined with Burrowstrike and Sand Storm can often kill Luna before she can do anything because of her low health and strength gain.
* Overall, Sand King forces Luna to play more defensively instead of offensively, and for the same reasons, Sand King makes a very powerful ally for Luna when they are in the same team.
Additional:
* Burrowstrike allows Sand King to escape from Eclipse or to close the gap on Luna and finish her off.
* Sand Storm allows Sand King to harass Luna more efficiently than she does with Lucent Beam, as it makes him invisible for it's duration and while in it, rendering him safe from both, Lucent Beam and Eclipse and forcing Luna to buy Dust of Appearance more often.
* Caustic Finale allows Sand King to deal serious damage to both, Luna and her allies, which is especially hazardous for Luna during the laning stage as Luna's attack range is short.
* Epicenter combined with Burrowstrike and Sand Storm can often kill Luna before she can do anything because of her low health and strength gain.
* Overall, Sand King forces Luna to play more defensively instead of offensively, and for the same reasons, Sand King makes a very powerful ally for Luna when they are in the same team.
Luna
* Lina has very high magic burst damage to use against the low-health-pool Luna. 
Laguna Blade can also be upgraded with Laguna Blade damage is Pure and pierces Spell Immunity to bypass Black King Bar, making Lina even more of a threat. Luna however, can easily counter this problem with 
Linken's Sphere, which is a common item for her.
* For the same reasons, Lina makes a very powerful ally for Luna when they are in the same team.
Luna
* Despite Ancient Apparition's fragileness, he can easily harass Luna on lane with 
Chilling Touch due to it's high range and damage. This can get even worse if Ancient Apparition buys Aghanim's Scepter and combines it with items that can give him bonus attack damage and attack speed.
* Chilling Touch combined with 
Ice Vortex can make it difficult for Luna to escape from 
Cold Feet
* 
Ice Blast can nullify any healing Luna receives and any attempt for her to save herself with 
Satanic, even through Black King Bar.
* For the same reasons, Ancient Apparition makes a very powerful ally for Luna when they are in the same team.
Outworld Destroyer
* Silencer's 
Intelligence Steal will heavily reduce Outworld Destroyer's damage output, particularly from Sanity's Eclipse.
* 
Last Word and 
Global Silence will take Outworld Destroyer out of the fight unless he has built Black King Bar.
Additional:
* Silencer's intelligence steal will heavily reduce Outworld Destroyer's damage output, especially if Destroyer dies a lot near Silencer and loses intelligence permanently.
* Global Silence and Last Word will render Outworld Destroyer helpless unless he has an item/ally to dispel silence.
Luna
* Zeus's highly damaging nuke spells with low cooldowns is not something Luna can go against, though Luna can win against Zeus in late game.
* 
Thundergod's Wrath can be used before a fight to harm Luna before she activates Black King Bar, reducing her survivability for that fight.
* For the same reasons, Zeus makes a very powerful ally for Luna when they are in the same team.
Outworld Destroyer
* 
Refraction blocks most of the damage dealt with Arcane Orb and Sanity's Eclipse if used correctly, and is difficult for Outworld Destroyer to deal with.
* If Astral Imprisonment is on cooldown, then an Outworld Destroyer slowed by 
Psionic Trap is an easy kill for Templar Assassin, especially during the laning stage.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .
Luna
* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.
Outworld Destroyer
* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, 
Magnus, 
Medusa, and 
Anti-Mage.
Luna
* Escape-type carries: 
Slark, 
Storm Spirit, Weaver.
Luna
* Because of her low range, Luna cannot easily destroy 
Healing Ward.
* Both 
Blade Fury and 
Omnislash are direct counters to Eclipse, offering Juggernaut spell immunity and invulnerabilty. Therefore, Luna will need assistance in taking down Juggernaut as going solo will not be successful.
* For the same reasons, Juggernaut makes a very powerful ally for Luna when they are in the same team.
Outworld Destroyer
* Heroes with built-in spell immunity can become immune to all of Outworld Destroyer's spells: 
Lifestealer's 
Rage and Juggernaut's Blade Fury.
Outworld Destroyer
* Astral Imprisonment allows Outworld Destroyer to save himself or his teamates during Omnislash.
* Juggernaut's low mana from his low intelligence gain means that he'll take a lot of damage from Sanity's Eclipse.
Luna
* Hard-hitters who relies mostly on raw stats or good passive and therefore make a perfect target for 
Dark Portrait: Naga Siren, Faceless Void, Terrorblade, 
Luna, Anti-Mage
Luna
* Heroes that can keep Luna locked down for a long time can be a threat (she is very item and spell dependent): Faceless Void, 
Legion Commander, Doom.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .
Outworld Destroyer
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, 
Phantom Assassin, 
Troll Warlord.
Luna
* Even though Moon Glaives can bounce between Meepo and his clones, Meepo can tank Eclipse because of his clones.
* 
Earthbind takes away Luna's mobility advantage.
* Meepo can shutdown Luna's split-push ability with his global presence.
* For the same reasons, Meepo makes a very powerful ally for Luna when they are in the same team.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Luna
* Primal Beast has a massive healthpool making it very difficult to get through it with a nuke such as Eclipse or Lucent Beam.
* Primal Beast is faster than Luna, as one of her main ways to escape danger, is very problematic for her in the laning stage especially.
* His ultimate goes through debuff immunity, making Luna's Black King Bar less effective.
* Primal Beast commonly buys 
Blade Mail which is a big problem for a single target bursting hero like Luna.
Outworld Destroyer
* Primal Beast is mostly played in the offlane role, so picking a carry who can escape from him is essential. Heroes such as Troll Warlord, Lone Druid and Outworld Destroyer, or generally any carry with a stun, slow or ability to fight back will stop him from having the good start he needs.
Outworld Destroyer
* Batrider prevents sharp and brazen attacks of the opponent. First he catches him in a 
Flaming Lasso, and then causes huge damage, in some cases even incompatible with life.
Additional:
* Batrider prevents sharp and brazen attacks of the opponent. First he catches him in a Flaming Lasso, and then causes huge damage, in some cases even incompatible with life.
Outworld Destroyer
* Shadow Demon, Outworld Destroyer and 
Tusk can all save a Lasso'd teammate with their defensive spells.
Luna
* Lucent Beam can be used to harass Muerta in lane.
* Luna's high movement speed can make it difficult for Muerta to hit her with 
Dead Shot and keep her trapped in 
The Calling.
* 
Pierce the Veil will not save Muerta from Luna at all. Instead, it will sentence her to death as it will amplify the magical damage from both, Lucent Beam and Eclipse, potentially turning Muerta's most powerful ability against her. Aghanim's Scepter upgraded Eclipse can also be used to counter-initiate against Muerta.
* Luna can use 
Aghanim's Shard upgraded Moon Glaives to reduce all the damage Muerta inflicts on Luna while also damaging Muerta if she is too close to Luna. Bear in mind, however, Aghanim's Shard upgraded Moon Glaives cannot damage Muerta while she is under effects of Pierce the Veil.
* As Luna naturally buys Black King Bar, she will be able to defend herself from Muerta's abilities. Luna can also buy 
Revenant's Brooch to attack Muerta even through Pierce the Veil.
* Overall, most of the attempts for Muerta to gank and kill Luna will hurt Muerta more than Luna.
Additional:
* Lucent Beam can be used to harass Muerta in lane.
* Luna's high movement speed can make it difficult for Muerta to hit her with Dead Shot and keep her trapped in The Calling.
* Pierce the Veil will not save Muerta from Luna at all. Instead, it will sentence her to death as it will amplify the magical damage from both, Lucent Beam and Eclipse, potentially turning Muerta's most powerful ability against her. Aghanim's Scepter upgraded Eclipse can also be used to counter-initiate against Muerta until Muerta buys Black King Bar.
* Luna can use Aghanim's Shard upgraded Moon Glaives to reduce all the damage Muerta inflicts on Luna while also damaging Muerta if she is too close to Luna. Bear in mind, however, Aghanim's Shard upgraded Moon Glaives cannot damage Muerta while she is under effects of Pierce the Veil as they deal physical damage.
* As Luna naturally buys Black King Bar, she will be able to defend herself from Muerta's abilities. Luna can also buy Revenant's Brooch to attack Muerta even through Pierce the Veil.
* Overall, most of the attempts for Muerta to gank and kill Luna will hurt Muerta more than Luna.
Outworld Destroyer
* Astral Imprisonment allows Outworld Destroyer to waste over half of Pierce the Veil, or protect an ally from Dead Shot's fear while also reducing Muerta's maximum mana.
* Sanity's Eclipse will deal massive damage to Muerta if her maximum mana gets too low. And even if she survives it, Sanity's Eclipse's Mana Allergy debuff will discourage her from using abilities as that will result in healing Outworld Destroyer.
Luna
* Although Anti-Mage can survive Luna's magical damage output with 
Counterspell, Luna's physical damage from Moon Glaives and 
Lunar Blessing can be fair enough to deal with him.
* Reckless use of 
Blink will allow Luna Eclipse can finish off Anti-Mage from early-to-mid stages of the game until Anti-Mage gets Manta Style, Aghanim's Scepter that will give him access to 
Blink Fragment and Aghanim's Shard which will allow Counterspell to weaken enemy spell damage.
* However, Luna needs to finish the match as quickly as possible, because Anti-Mage is a hero who has a big advantage in longer matches once he farms items he needs for teamfights.
Outworld Destroyer
* 
Arcane Orb's pure damage, making Counterspell ineffective.
* Sanity's Eclipse will hit Anti-Mage while he is disabled from Astral Imprisonment, and forces him to take heavy damage due to his low intelligence.
* 
Essence Flux keeps Outworld Destroyer at high mana, thus greatly reducing the damage from Mana Void.
Additional:
* Counterspell doesn't work versus Arcane Orb because it does pure damage.
* Anti-Mage cannot burn all of Outworld Destroyer's mana without disables due to Essence Flux.
* Anti-Mage's Manta Style illusions are quickly destroyed by Arcane Orb.
* However, if the enemy has multiple means of removing mana, 
Mana Void becomes a threat to Outworld Destroyer, Anti-Mage has better mobility than Outworld Destroyer with Blink, and Counterspell blocks a large portion of the damage from Sanity's Eclipse.
Luna
* If Luna chooses to use Eclipse in anticipation right before Spirit Breaker gets to her with Charge of Darkness, she will be able to kill Spirit Breaker before he will be able to kill her as Spirit Breaker's attack speed is rather low.
* Meanwhile, when Spirit Breaker is focusing on any of Luna's allies with Charge of Darkness, Aghanim's Scepter upgraded Eclipse can be used to counter-initate against Spirit Breaker.
* Aghanim's Shard upgraded Moon Glaives allows Luna to reduce damage from Greater Bash and Nether Strike inflicts on her, and damage Spirit Breaker whenever he is close to her, even while he is invisible.
* Lucent Beam can be used to cancel Spirit Breaker's Charge of Darkness under the condition that Luna is able to cast it on time. Lucent Beam can also be used to cancel Nether Strike. But bear in mind, however, that Spirit Breaker can counter this with 
Planar Pocket from Aghanim's Shard which can be used to reflect Lucent Beam back at Luna.
* If Luna buys Linken's Sphere, it will become nearly impossible for Spirit Breaker to reach Luna unless some of Spirit Breaker's allies can pop it and put it on a cooldown.
* Even though Spirit Breaker can evade all of Luna's abilities with 
Shadow Blade, smart Luna will always buy Dust of Appearance to provide vision on Spirit Breaker to her and her team. Luna can also buy 
Gleipnir to counter Spirit Breaker's Charge of Darkness and Shadow Blade combo.
Additional:
* If Luna chooses to use Eclipse in anticipation right before Spirit Breaker gets to her with Charge of Darkness, she will be able to kill Spirit Breaker before he will be able to kill her as Spirit Breaker's attack speed is rather low.
* Meanwhile, when Spirit Breaker is focusing on any of Luna's allies with Charge of Darkness, Aghanim's Scepter upgraded Eclipse can be used to counter-initate against Spirit Breaker.
* Aghanim's Shard upgraded Moon Glaives allows Luna to reduce damage from Greater Bash and Nether Strike inflicts on her, and damage Spirit Breaker whenever he is close to her, even while he is invisible.
* Lucent Beam can be used to cancel Spirit Breaker's Charge of Darkness under the condition that Luna is able to cast it on time. Lucent Beam can also be used to cancel Nether Strike. But bear in mind, however, that Spirit Breaker can counter this with Planar Pocket from Aghanim's Shard which can be used to reflect Lucent Beam back at Luna.
* If Luna buys Linken's Sphere, it will become nearly impossible for Spirit Breaker to reach Luna unless some of Spirit Breaker's allies can pop it and put it on a cooldown.
* Even though Spirit Breaker can evade all of Luna's abilities with Shadow Blade, smart Luna will always buy Dust of Appearance to provide vision on Spirit Breaker to her and her team. Luna can also buy Gleipnir to counter Spirit Breaker's Charge of Darkness and Shadow Blade combo.
Outworld Destroyer
* Astral Imprisonment can be used to protect allies by imprisoning either them or Spirit Breaker.
* Arcane Orb will heavily drain Spirit Breaker's maximum mana, rendering him almost useless and unable to cast spells. And considering how Spirit Breaker's intelligence is very low, Sanity's Eclipse will deal a lot of damage to him.
* Even if Spirit Breaker survives Sanity's Eclipse, mana allergy applied by the Sanity's Eclipse will discourage Spirit Breaker from using his abilities as it will cause him to lose health and heal Outworld Destroyer.
Luna
* Luna's Lucent Beams and Eclipse will prevent Earthshaker from initiating or re-initiating.
* Aghanim's Scepter upgraded Eclipse can be used to counter-initiate against Earthshaker after he uses Aghanim's Scepter upgraded 
Enchant Totem.
* Skilled Luna can buy either {I|Gleipnir
Additional:
* Luna's Lucent Beams and Eclipse will prevent Earthshaker from initiating or re-initiating.
* Aghanim's Scepter upgraded Eclipse can be used to counter-initiate against Earthshaker after he uses Aghanim's Scepter upgraded Enchant Totem.
* Skilled Luna can buy either {I|Gleipnir
Outworld Destroyer
* Outworld Destroyer's pure and magical damage is particularly effective against Earthshaker.
* Astral Imprisonment catches Earthshaker while he blinks in, preventing him from executing his combo.
* Earthshaker has mana troubles, and Outworld Destroyer's abilities can press this by stealing intelligence comes from Arcane Orb, therefore depleting his mana pool and mana regeneration.
* Sanity's Eclipse deals high damage to Earthshaker, due to his low intelligence and mana pool.
Luna
* Without Black King Bar, Luna will be able to cancel Enigma's 
Black Hole from safe distance with her Lucent Beam or with 0.25s Eclipse Lucent Ministun talent for Eclipse and counter-initiate with Eclipse. This can get even worse for Enigma once Luna gets Aghanim's Scepter and combines it with 0.25s Eclipse Lucent Ministun talent that will allow Luna to use Eclipse from safe distance.
* If Luna chooses to use Eclipse in anticipation right after Enigma jumps in with Blink Dagger, she will be able to kill Enigma before he even gets a chance to use Black Hole. Aghanim's Scepter upgraded Eclipse can be used to counter-initiate against Enigma from safe distance if he has no Black King Bar available to use.
* Luna commonly buys Satanic, which can help her recover from Enigma's Black Hole in case she survives it.
* Moon Glaives combined with Lunar Blessing can make a short work of Enigma's Eidolons before Luna uses Eclipse. Aghanim's Shard upgraded Moon Glaives can be used to reduce damage Luna will take from Enigma's Eidolons and Black Hole if used in anticipation while also clearing waves of Enigma's Eidolons and damaging Enigma if he is too close to Luna.
* Bear in mind, however, that once Enigma gets Black King Bar, Luna will be out of solutions to cancel Black Hole, and going for 
Abyssal Blade on Luna can be risky due to Abyssal Blade's very short cast range.
Additional:
* Without Black King Bar, Luna will be able to cancel Enigma's Black Hole from safe distance with her Lucent Beam or with 0.25s Eclipse Lucent Ministun talent and counter-initiate with Eclipse. This can get even worse for Enigma once Luna gets Aghanim's Scepter and combines it with 0.25s Eclipse Lucent Ministun talent that will allow Luna to use Eclipse from safe distance.
* If Luna chooses to use Eclipse in anticipation right after Enigma jumps in with Blink Dagger, she will be able to kill Enigma before he even gets a chance to use Black Hole.
* Luna commonly buys Satanic, which can help her recover from Enigma's Black Hole in case she survives it.
* Moon Glaives combined with Lunar Blessing can make a short work of Enigma's Eidolons before Luna uses Eclipse.
* Bear in mind, however, that once Enigma gets Black King Bar, Luna will be out of solutions to cancel Black Hole, and going for Abyssal Blade on Luna can be risky due to Abyssal Blade's very short cast range.
Outworld Destroyer
* Astral Imprisonment can save allies from a Black Hole combo. When upgraded with Aghanim's Scepter and Aghanim's Shard, it becomes exceedingly difficult for Enigma to land a good Black Hole against Outworld Destroyer and his team.
* Astral Imprisonment can also cancel Black Hole while Enigma does not have Black King Bar.
* Arcane Orb and Sanity's Eclipse can often make a short work out of Enigma and his Eidolons.
Luna
* Even though Wraith King can easily get a chance to retaliate with 
Reincarnation after Luna uses Eclipse against him, smart Luna can also turn Reincarnation against him by using Eclipse right after Reincarnation triggers and gets on cooldown, giving Luna an element of surprise she can use against Wraith King.
* Moon Glaives can be used to clear the waves of Wraith King's skeleton warriors summoned from 
Vampiric Spirit.
Additional:
* Even though Wraith King can easily get a chance to retaliate with Reincarnation after Luna uses Eclipse against him, smart Luna can also turn Reincarnation against him by using Eclipse right after Reincarnation triggers and gets on cooldown, giving Luna an element of surprise she can use against Wraith King.
* Moon Glaives can be used to clear the waves of Wraith King's skeleton warriors summoned from Vampiric Spirit.
Outworld Destroyer
* Sanity's Eclipse does massive damage to Wraith King who naturally has a low mana pool and typically doesn't build items to increase it.
* 
Wraithfire Blast's slow projectile speed makes it easy to avoid using Astral Imprisonment.
Luna
* Cold Embrace is no salvation against Lucent Beam and Eclipse.
* Moon Glaives will not hit a hero affected by Winter's Curse, making it weak against allies, but strong versus enemies.
* Luna has better night vision provided by Lunar Blessing than Winter Wyvern when affected by Arctic Burn.
Additional:
* Cold Embrace is no salvation against Lucent Beam and Eclipse.
* Moon Glaives will not hit a hero affected by Winter's Curse, making it weak against allies, but strong versus enemies.
* Luna has better night vision provided by Lunar Blessing than Winter Wyvern when affected by Arctic Burn.
Outworld Destroyer
* Outworld Destroyer's pure damage from Arcane Orb can go through 
Cold Embrace.
* Outworld Destroyer can negate the healing from Cold Embrace using Astral Imprisonment, and steal mana while doing so.
* Outworld Destroyer's damage during 
Winter's Curse is reduced due to Arcane Orb being unable to target allies.
Additional:
* Winter Wyvern must never put her allies in Cold Embrace against Outworld Destroyer as Arcane Orb will continue to deal damage to the defenseless hero.
* Arcane Orb does not hit his allies when he is taunted by Winter's Curse, making it weak against allies, but strong versus enemies.
* Astral Imprisonment can protect a target inflicted with Winter's Curse.
Luna
* Guardian Angel does not offer protection from Eclipse, though it will negate damage from Moon Glaives.
* Luna's high magical damage from Lucent Beam and Eclipse can often finish allied heroes before Omniknight can save them with 
Purification.
* Likewise, Luna's high physical damage from Moon Glaives and Lunar Blessing is strong enough to counter debuff immunity from 
Repel.
Additional:
* Guardian Angel does not offer protection from Eclipse, though it will negate damage from Moon Glaives.
* Luna's high magical damage from Lucent Beam and Eclipse can often finish allied heroes before Omniknight can save them with Purification.
Outworld Destroyer
* Arcane Orb's pure damage penetrates Guardian Angel's defense.
* Astral Imprisonment's mana steal is devastating to Omniknight's already low mana pool.
Luna
* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: 
Monkey King, 
Alchemist, 
Timbersaw.
Outworld Destroyer
* Arcane Orb's pure damage ignores Timbersaw's 
Reactive Armor.
* Astral Imprisonment, if timed correctly, can interrupt 
Timber Chain, preventing him from escaping.
Additional:
* Arcane Orb deals constant pure damage, which bypasses Timbersaw's Reactive Armor.
* Sanity's Eclipse can hit targets inside Astral Imprisonment, which helps Outworld Destroyer finish off Timbersaw before he escapes with Timber Chain. It can also drain his mana, limiting his ability to escape should he survive.
Luna
* Lunar Blessing gives allies bonus damage and armor required to endure against Atrophy Aura early on.
* Eclipse can be devastating for Underlord's team when they're grouped up for Fiend's Gate, it can also be used to intercept arrivals with Fiend's Gate. And Pit of Malice does not prevent Luna to use it.
* To make things even better, Aghanim's Scepter upgraded Eclipse can finish off Underlord or any of his teammates escape attempts with Fiend's Gate if timed correctly.
Additional:
* Lunar Blessing gives allies bonus damage required to endure against 
Atrophy Aura in most stages of the game.
* Eclipse can be devastating for Underlord's team when they're grouped up for 
Fiend's Gate. It can also be used to intercept arrivals with Fiend's Gate. And 
Pit of Malice does not prevent Luna from using it.
* To make things even worse, Aghanim's Scepter upgraded Eclipse can finish off Underlord or any of his teammates escape attempts with Fiend's Gate if timed correctly.
Outworld Destroyer
* Tanky melee heroes that can easily be kited, which allows Outworld Destroyer to deal heavy damage with Arcane Orb from a distance: 
Sven, 
Underlord, 
Bristleback.
Additional:
* Arcane Orb's pure damage can do great damage to Underlord.
* Sanity's Eclipse can tear down Underlord's health by a large amount, since his mana pool is very low compare to Outworld Destroyer's high mana pool.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Luna's Moon Glaives combined with Lunar Blessing can easily kill Chen's creeps.
* Eclipse can be used after Luna clears all of Chen's creeps to easily kill Chen or any of his allies before he can save them with 
Hand of God. This can get even worse if Luna buys Aghanim's Scepter. And Chen is not a hero that likes to buy Black King Bar to counter this problem.
Additional:
* Luna's Moon Glaives combined with Lunar Blessing can easily kill Chen's creeps.
* Eclipse can be used after Luna clears all of Chen's creeps to easily kill Chen or any of his allies before he can save them with Hand of God. This can get even worse if Luna buys Aghanim's Scepter. And Chen is not a hero that likes to buy Black King Bar to counter this problem.
Outworld Destroyer
* Arcane Orb and Sanity's Eclipse can often kill Chen or his allies before he can save them with Hand of God.
* Arcane Orb, Astral Imprisonment and Sanity's Eclipse can clear waves of Chen's converted creeps.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Luna's Moon Glaives and Lunar Blessing can clear waves of Naga Siren's illusions from 
Mirror Image.
* Once Naga Siren's illusions are cleared with Aghanim's Shard upgraded Moon Glaives, Eclipse can often finish off Naga Siren before she can escape with 
Song of the Siren.
* A well-timed Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Lucent Ministun talent can be casted at long range and allow Luna to burst down Naga Siren faster and repetively stun Naga Siren, preventing her from escaping with Song of the Siren and 
Town Portal Scroll without getting caught in it's range.
* Luna is a natural Black King Bar wielder unlike Naga Siren who barely goes for it, which allows Luna to freely attack Naga Siren during Song of the Siren and potentially get rid of the most of the damage and crowd-control from Naga Siren.
Additional:
* Luna's Moon Glaives and Lunar Blessing can clear waves of Naga Siren's illusions from Mirror Image, especially when combined with Gleipnir and Manta Style. Aghanim's Shard upgraded Moon Glaives can also be used to destroy Naga Siren's illusions and damage the real Naga Siren if they are too close to Luna while also reducing any damage Naga Siren inflicts on Luna for their duration.
* Once Naga Siren's illusions are cleared, Eclipse can often finish off Naga Siren before she can escape with Song of the Siren.
* A well-timed Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Lucent Ministun talent can be casted at long range and allow Luna to burst down Naga Siren faster and repetively stun Naga Siren, preventing her from escaping with Song of the Siren and Town Portal Scroll without getting caught in it's range.
* Luna is a natural Black King Bar wielder unlike Naga Siren who barely goes for it, which allows Luna to freely attack Naga Siren during Song of the Siren and potentially get rid of the most of the damage and crowd-control from Naga Siren.
Outworld Destroyer
* Arcane Orb allows Outworld Destroyer's attacks to deal pure damage that can bypass Naga Siren's armor, and which can clear her illusions in no time.
* Astral Imprisonment can be used to harass Naga Siren by reducing her maximum mana and to prevent Naga Siren from escaping with Song of the Siren. Outworld Destroyer can also use Astral Imprisonment to protect himself from Naga Siren.
* Sanity's Eclipse will most likely instantly kill Naga Siren along with her illusions. Even if Naga Siren survives Sanity's Eclipse, it's mana allergy debuff will discourage Naga Siren from using her abilities as the mana allergy will heal Outworld Destroyer if she uses them for it's duration.
Luna
* A couple of long-range heroes with excellent laning like Mirana, Lina, Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Luna
* Even though Luna has a hard time laning against Necrophos, his 
Ghost Shroud won’t protect him in teamfights because it will increase the damage from Lucent Beam and Eclipse.
* Luna is a natural Black King Bar wielder, and none of Necrophos's spells can bypass spell immunity outside of 
Heartstopper Aura.
Additional:
* Even though Luna has a hard time laning against Necrophos, his Ghost Shroud won’t protect him in teamfights because it will increase the damage from Lucent Beam and Eclipse.
* Luna is a natural Black King Bar wielder, and none of Necrophos's spells can bypass spell immunity outside of Heartstopper Aura.
Outworld Destroyer
* Outworld Destroyer is not exceptionally dangerous to Necrohpos because of his Ghost Shroud, but his Astral Imprisonment can save his allies from Necrophos's Reaper's Scythe, though only if he uses it at the right time, If an Outworld Destroyer is nearby, Necrophos should not use Reaper's Scythe unless he has banished himself, or has banished two heroes within 15 seconds
Luna
* Heroes that rely on base damage: Luna, Phantom Lancer are easily countered with Anchor Smash.
Luna
* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though 
Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that Lucent Beam and Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's 
Kraken Shell.
Additional:
* Luna often builds Black King Bar, and none of Tidehunter's spells can bypass spell immunity.
* Though Anchor Smash can weaken Luna's physical damage, it does not weaken her magical damage, which means that Lucent Beam and Eclipse deal a lot of magic damage in the early and mid-game, which can bypass Tidehunter's Kraken Shell.
Outworld Destroyer
* Kraken Shell's dispel does not restore mana lost through Astral Imprisonment, and the stolen mana can really hurt Tidehunter's ability to initiate
* Arcane Orb high pure damage ignores Tidehunter's Armor, and is barely affected by his Kraken Shell's damage block
* It is also completely unaffected by Anchor Smash, due to it relying on Outworlds Mana pool
* Sanity's Eclipse is effective on Tidehunter's poor mana pool, While it is reduced by Kraken Shell, the damage reduction is negligible.
Luna
* Heroes that can keep Luna locked down for a long time can be a threat (she is very item and spell dependent): Faceless Void, Legion Commander, Doom.
Luna
* A well-timed Eclipse before a Duel usually prevents Legion Commander from winning Duels, if Luna is the target.
* Meanwhile, when Luna is not a target, Eclipse and Lucent Beam can also help an ally win a Duel against Legion Commander.
* However, skilled Legion Commander will always buy a Black King Bar to block Eclipse and Lucent Beam or Aghanim's Scepter to reduce it's damage.
Additional:
* A well-timed Eclipse before a Duel usually prevents Legion Commander from winning Duels if Luna is the target. Luna can also buy Linken's Sphere to block Duel.
* Meanwhile, when Luna is not a target, Eclipse and Lucent Beam can also help an ally win a Duel against Legion Commander.
* Bear in mind, however, that skilled Legion Commander will always buy a Black King Bar to block Eclipse and Lucent Beam or Aghanim's Scepter to reduce their damage.
Outworld Destroyer
* Astral Imprisonment prevents Legion Commander from killing her opponents in Duels.
Additional:
* Outworld Destroyer can save an ally hero caught by 
Duel with Astral Imprisonment, and he can inflict heavy damage on Legion Commander with Arcane Orb to aid his ally. However, if he gets caught, he is unlikely to survive the duel, due to his lack of durability.
Outworld Destroyer
* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from 
Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* If carefully timed, Aghanim's Scepter upgraded Eclipse combined with 0.2s Eclipse Lucent Ministun talent can quickly finish off Terrorblade before he can get a chance to save himself with 
Sunder due to its high magical damage as long as Terrorblade has no Black King Bar.
* Moon Glaives allows Luna to clear Terrorblade's illusions from both, Conjure Image and Manta Style, this can be particularly advantegous for Luna if she has Manta Style. Just bear in mind, however, that 
Reflection can be used to turn Moon Glaives against Luna during laning phase.
* Luna very often builds Satanic and Black King Bar, which allows it either to protect herself from Sunder or nullify it's effects.
* Luna can also buy 
Monkey King Bar to help her deal with Terrorblade's high armor, which is a common item on Luna.
Additional:
* If carefully timed, Aghanim's Scepter upgraded Eclipse can quickly finish off Terrorblade before he can get a chance to save himself with Sunder due to its high magical damage if Terrorblade has no Black King Bar available to use.
* Moon Glaives allows Luna to clear Terrorblade's illusions from both, Conjure Image and Manta Style, this can be particularly advantegous for Luna if she has Manta Style. Just bear in mind, however, that Reflection can be used to turn Moon Glaives against Luna during laning phase. Aghanim's Shard upgraded Moon Glaives can be used to reduce damage Luna will take from Terrorblade and his illusions while also clearing waves of them and damaging Terrorblade if he is too close to Luna.
* Luna very often bulds Satanic and Black King Bar as well as it's alternative item Linken's Sphere, which allows her either to protect herself from Sunder or nullify it's effects.
* Luna can also buy Monkey King Bar to help her deal with Terrorblade's high armor, which is a common item on Luna. Likewise Luna can also buy Revenant's Brooch or Gleipnir whose attacks can also ignore Terrorblade's high armor.
Outworld Destroyer
* Most Illusion based heroes (like Chaos Knight and Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.
Additional:
* Arcane Orb deals pure damage against the real Terrorblade, which allows it to bypass his high base armor.
* Arcane Orb and Sanity's Eclipse will make very short work of Terrorblade and his illusions.
* Aghanim's Shard upgraded Astral Imprisonment can be used to save an ally on which Terrorblade has used Sunder.
Outworld Destroyer
* Astral Imprisonment protects an ally for much of Rolling Thunder's duration, especially at the lower levels. As Rolling Thunder has a considerable cast animation, an Outworld Destroyer with Blink Dagger can initiate on him and destroy his timing.
Luna
* A couple of long-range heroes with excellent laning like Mirana, Lina, Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Luna
* Even though Luna is the kind of hero that Mirana can handle due to 
Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade 
Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with 
Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Outworld Destroyer
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Luna
* If Luna can use Eclipse in anticipation, Magnus will be killed before he can even manages to cast 
Reverse Polarity.
* Aghanim's Scepter upgraded Eclipse is a very good counter-initiation tool against Magnus when he casts Reverse Polarity, granted as long as Luna can cast it from safe distance.
Outworld Destroyer
* Arcane Orb's constant pure damage output is devastating to Dragon Knight.
* Dragon Knight's relatively low mana pool leads to heavy damage from Sanity's Eclipse, which also bypasses his armor.
Outworld Destroyer
* Astral Imprisonment is a versatile nuisance:
* If it is cast on a low-enough-health unit at least 1 second into Shallow Grave's duration, the Shallow Grave will end during the imprisonment, and the target will take lethal damage when released.
* It can be used remove Dazzle from the fight at a time he could have saved someone.
* It lets himself or an ally dodge all of Poison Touch's effects, for long enough to recover their Blink Dagger.
Luna
* Lucent Beam allows Luna to easily cancel Freezing Field.
* Without Black King Bar protection, Lucent Beam and Eclipse can make a short work out of Crystal Maiden's abysmal health.
* Skilled Luna will always buy Dust of Appearance, allowing her team to have a vision on Crystal Maiden while invisible and during channeling Freezing Field.
* Even with Black King Bar, Luna can still inflict considerable damage on Crystal Maiden with her attacks, which get empowered with Moon Glaives and Lunar Blessing, also smart and skilled Luna will buy Abyssal Blade to cancel Freezing Field even through Black King Bar in case of emergency. And since Crystal Maiden rarely buys Linken's Sphere, this can be a very big problem for her.
Additional:
* Lucent Beam allows Luna to easily cancel Freezing Field.
* Without Black King Bar protection, Lucent Beam and Eclipse can make a short work out of Crystal Maiden's abysmal health.
* Skilled Luna will always buy Dust of Appearance, allowing her team to have a vision on Crystal Maiden while invisible and during channeling Freezing Field.
* Even with Black King Bar, Luna can still inflict considerable damage on Crystal Maiden with her attacks, which get empowered with Moon Glaives and Lunar Blessing, also smart and skilled Luna will buy Abyssal Blade to cancel Freezing Field even through Black King Bar in case of emergency. Forcing Crystal Maiden to buy Linken's Sphere.
Luna
* Lucent Beam and Eclipse with ministun talent can be used to cancel Requiem of Souls if Shadow Fiend does not have Black King Bar. Likewise, since Shadow Fiend is prone to buying Blink Dagger, an ill-timed Blink Dagger can give Luna a free chance to counter-initiate with Eclipse.
* Moon Glaives and Lunar Blessing allow Luna to outfarm Shadow Fiend in lane and the high physical damage output they provide her can also help her deal with Shadow Fiend even when he buys Black King Bar in late game.
* A well timed Eclipse will burst and kill Shadow Fiend before he even either initiates or gets a chance to retaliate, especially when equipped with Aghanim's Scepter and 
Ethereal Blade, this could become even worse for Shadow Fiend if he does not have Black King Bar. But bear in mind however, that smart and skilled Shadow Fiend can buy 
Wind Waker to counter this issue.
* Even though Shadow Fiend can evade all of Luna's abilities with Shadow Blade, smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.
Additional:
* Lucent Beam and Eclipse with ministun talent can be used to cancel Requiem of Souls if Shadow Fiend does not have Black King Bar. Likewise, since Shadow Fiend is prone to buying Blink Dagger, an ill-timed Blink Dagger can give Luna a free chance to counter-initiate with Eclipse.
* Moon Glaives and Lunar Blessing allow Luna to outfarm Shadow Fiend in lane and the high physical damage output they provide her can also help her deal with Shadow Fiend even when he buys Black King Bar in late game.
* A well timed Eclipse will burst and kill Shadow Fiend before he even either initiates or gets a chance to retaliate, especially when equipped with Aghanim's Scepter and Ethereal Blade, this could become even worse for Shadow Fiend if he does not have Black King Bar. But bear in mind however, that smart and skilled Shadow Fiend can buy Wind Waker to counter this issue.
* Even though Shadow Fiend can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.
Luna
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Additional:
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Outworld Destroyer
* Outworld Destroyer doesn't care if Razor steals his damage because he does most of his damage through Arcane Orb.
* Astral Imprisonment can prevent Razor from using the stolen damage from Static Link or chasing with Eye of the Storm.
* Sanity's Eclipse will do a ton of damage to Razor due to his low mana pool.
Outworld Destroyer
* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.
Luna
* Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's 
Diabolic Edict, 
Lightning Storm and 
Pulse Nova abilities. Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Additional:
* Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse can be used to cancel both, Tether and Relocate.
* Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Luna
* All assassin-type carries in a one against one situation: Meepo, Phantom Assassin, Riki, 
Ursa. Luna's only chances are that she buys Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.
Luna
* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned 
Phantom Strike will make Phantom Assassin an easy target for counter-attack with Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even better if Luna buys Aghanim's Scepter.
* Moon Glaives can ignore 
Blur's evasion if Luna attacks an enemy near Phantom Assassin.
* Luna can counter Blur's evasion by buying either 
Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about 
Fan of Knives from Aghanim's Shard and 
Coup De Grace, as Fan of Knives can disable Moon Glaives and Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be solved by buying Ethereal Blade, which is a situational item on Luna.
Additional:
* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned Phantom Strike will make Phantom Assassin an easy target for counter-attack with Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even worse if Luna buys Aghanim's Scepter.
* Moon Glaives can ignore Blur's evasion if Luna attacks an enemy near Phantom Assassin. Aghanim's Shard upgraded Moon Glaives can also reduce damage from Coup De Grace and Moon Glaives Phantom Assassin inflicts on Luna and damage Spirit Phantom Assassin she is close to her. And the Aghanim's Shard upgraded Moon Glaives have true strike for their duration, which renders Blur's evasion insignificant.
* Luna can counter Blur's evasion by buying either Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can deal health-based damage to Luna and disable Moon Glaives and Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be partially solved by buying Ethereal Blade, which is a situational item on Luna.
Outworld Destroyer
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.
Outworld Destroyer
* Outworld Destroyer can steal more mana with Astral Imprisonment from 
Skywrath Mage with 
Shield of the Scion (granted by Aghanim's Shard). Shield of the Scion grants Skywrath Mage bonus intelligence every time he deals magic damage to an enemy hero with his abilities. The higher his intelligence, the larger his mana pool. Since Astral Imprisonment steals based on the target's max mana, Outworld Destroyer can steal much more mana from Skywrath Mage.
Luna
* Even though Luna has a hard time laning against Viper due to 
Nethertoxin being able to disable Moon Glaives and Lunar Blessing, Luna can take out Viper once she builds either Black King Bar or Silver Edge which will allow her to attack Viper freely.
* Eclipse can often finish off Viper from early-to-mid stages of the game before he can retaliate as 
Corrosive Skin gives little magic resistance to him early on.
* Manta Style is an item that Luna commonly buys in most of the games, which lets her disjoint 
Viper Strike. Additionally, illusions from Manta Style can make Viper waste time attacking them.
Additional:
* Even though Luna has a hard time laning against Viper due to Nethertoxin being able to disable Moon Glaives and Lunar Blessing, Luna can take out Viper once she builds either Black King Bar or Silver Edge which will allow her to attack Viper freely.
* Eclipse can often finish off Viper from early-to-mid stages of the game before he can retaliate as Corrosive Skin gives little magic resistance to him early on.
* Manta Style is an item that Luna commonly buys in most of the games, which lets her disjoint Viper Strike. Additionally, illusions from Manta Style can make Viper waste time attacking them.
Outworld Destroyer
* Astral Imprisonment can allow Outworld Destroyer to save himself or allies from Kunkka's full kit.
* Sanity's Eclipse deal a large amount of damage, as Kunkka's mana pool is much smaller than Outworld Destroyer's.
* Arcane Orb deals pure damage, shredding through Kunkka and his team even with Ghostship's buff.
Luna
* Luna's Moon Glaives will not trigger 
Retaliate if they hit some other target first. Also Luna commonly buys items that provide lifesteal such as Satanic, which lets her heal from the damage of Retaliate, meaning that Retaliate has little effect against her.
* Eclipse can be used to counter-initiate against Centaur Warrunner after he jumps in with Blink Dagger, and initiates with 
Hoof Stomp. But remember that Centaur Warrunner can resolve this problem by buying 
Hood of Defiance and it's upgrade 
Pipe of Insight to diminish its damage. Or Blade Mail to reflect the damage of the Eclipse back at Luna.
* Luna also commonly buys Black King Bar, which will allow her to protect herself from both, Centaur Warrunner's abilities (except for the Retaliate), and damage reflect from Blade Mail.
Additional:
* Luna's Moon Glaives will not trigger Retaliate if they hit some other target first. Also Luna commonly buys items that provide lifesteal such as Satanic, which lets her heal from the damage of Retaliate, meaning that Retaliate has limited effect against her.
* Eclipse can be used to counter-initiate against Centaur Warrunner after he jumps in with Blink Dagger, and initiates with Hoof Stomp. But remember that Centaur Warrunner can resolve this problem by buying Hood of Defiance and it's upgrade Pipe of Insight to diminish its damage. Or Blade Mail to reflect the damage of the Eclipse back at Luna.
* Luna also commonly buys Black King Bar, which will allow her to protect herself from both, Centaur Warrunner's abilities (except for the Retaliate), and damage reflect from Blade Mail.
Outworld Destroyer
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: 
Disruptor, Death Prophet, 
Enigma, Faceless Void, 
Invoker, 
Lich, Magnus, 
Mars, Medusa, Outworld Destroyer, 
Phoenix, 
Puck, 
Queen of Pain, 
Shadow Fiend, 
Treant Protector, Underlord, 
Winter Wyvern, 
Witch Doctor, 
Zeus.
Luna
* Though Bane's 
Enfeeble can weaken Luna's physical damage output, it still does not weaken her magical damage output, although it will still reduce her cast range.
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Bane while he is channeling Fiend's Grip.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetively stun Bane, and can even discourage him from even trying to use Fiend's Grip.
Additional:
* Though Bane's Enfeeble can weaken Luna's physical damage output, it still does not weaken her magical damage output (although it can still disable her cast range).
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Bane while he is channeling Fiend's Grip.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetively stun Bane, and can even discourage him from even trying to use Fiend's Grip.
* Smart and skilled Luna can buy Abyssal Blade to cancel 
Fiend's Grip even through Black King Bar in case of emergency. Forcing Bane to buy Linken's Sphere.
Outworld Destroyer
* Heroes with hiding abilities can protect disabled allies: Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter.
Luna
* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.
Additional:
* Luna's Moon Glaives and Lunar Blessing can help her destroy Tombstone easily, and this becomes more effective if Luna is equipped with Manta Style.
* Spell Immunity of Zombies from Tombstone is a total disadvantage against Luna because Eclipse will strike only Undying, which can turn Undying's own ability against him.
* Though Undying often builds Blade Mail which can turn Luna's burst damage against her, Luna often builds Black King Bar which will allow her to attack Undying freely because Blade Mail cannot pierce spell immunity.
Luna
* Even though Luna is the kind of hero that Bounty Hunter can handle due to Shadow Walk rendering him safe from Eclipse, smart Luna will always buy Dust of Appearance, allowing her to provide vision on him to her team, and possibly, kill Bounty Hunter with Eclipse.
Outworld Destroyer
* The pure damage provided by Arcane Orb is a great addition for killing Ember Spirit.
* Astral Imprisonment fully negates all magic damage of Flame Guard and Searing Chains and will temporarily save himself from Sleight of Fist's physical damage, and Ember Spirit is not a hero that can counter these skills.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Outworld Destroyer
* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.
Outworld Destroyer
* Outworld Destroyer's pure and magical damage is particularly effective against Axe.
* Astral Imprisonment is an excellent way to defend against an initiating Axe.
* Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* 
Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Destroyer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.
Luna
* Moon Glaives is very effective against Visage because not only it can easily destroy Visage's Familiars, but can also remove one instance of Gravekeeper's Cloak upon each hit to Visage, leaving him susceptible to damage.
* Once Visage's Familiars are picked off and all instances of Gravekeeper's Cloak are removed, Luna will be able to easily kill Visage with Eclipse.
Additional:
* Moon Glaives is very effective against Visage because not only it can easily destroy Visage's Familiars, but can also remove one instance of Gravekeeper's Cloak upon each hit to Visage, leaving him susceptible to damage.
* Once Visage's Familiars are picked off and all instances of Gravekeeper's Cloak are removed, Luna will be able to easily kill Visage with Eclipse.
Luna
* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: Monkey King, Alchemist, Timbersaw.
Luna
* Moon Glaives can ignore certain abilities that either trigger on attack or give evasion under the condition that the heroes who have them are not primary targets. Examples include: 
Centaur Warrunner, 
Windranger, Phantom Assassin, 
Hoodwink etc.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Outworld Destroyer
* Most Illusion based heroes (like Chaos Knight and Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's 
Death Ward, 
Shadow Shaman's 
Shackles, 
Lion's 
Mana Drain, 
Bane's Fiend's Grip, 
Pudge's 
Dismember, 
Crystal Maiden's 
Freezing Field, 
Pugna's 
Life Drain, 
Dawnbreaker's 
Solar Guardian, and Naga Siren's 
Reel In from Aghanim's Scepter.
Outworld Destroyer
* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, 
Silencer.
Additional:
* Outworld Destroyer can dodge 
Life Break with Astral Imprisonment, leaving him unharmed while Huskar loses HP.
* Sanity's Eclipse can deal massive damage to Huskar before he builds up his 
Berserker's Blood stacks due to Huskar's low mana pool.
Luna
* Illusion heroes like the aforementioned Phantom Lancer or Naga Siren, or heroes that tend to buy Manta Style, like Luna or Juggernaut, will give Slardar a hard time, as his damage is single-targeted.
Luna
* Frail heroes who lack mobility can also be an easy target to lock down with Chronosphere, such as Drow Ranger, Luna, Sniper, Terrorblade.
Luna
* Luna's Eclipse can be used for counter-attacks and interception against gap-closing heroes who use their blinking abilities without protection or who recklessly jump on her, provided that Luna is able to cast it in time. Examples include: Queen of Pain, Riki, Phantom Assassin, Faceless Void and pretty much any hero who relies on Blink Dagger to close the gap.
Outworld Destroyer
* Any hero that can nullify effects of Chronosphere: (
Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, 
Earth Spirit with Aghanim's Scepter) or protecting him in other ways (
Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.
Luna
* Even with Black King Bar, Pudge's 
Meat Hook and Dismember can still disable Luna for a fairly long time.
* Many stacks of 
Flesh Heap will make it difficult for Luna to burst down Pudge with Eclipse. Aghanim's Shard upgraded Dismember can also allow Pudge to save an allied hero from being killed by Eclipse.
* Bear in mind, however, that Luna can cancel Dismember if some of her allies are targets. Which may force Pudge to buy Black King Bar earlier.
* For the same reasons, Pudge makes a very powerful ally for Luna when they are in the same team.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Outworld Destroyer
* Sanity's Eclipse deals more damage the less max mana the heroes hit by it have, making Pudge an ideal target.
* Outworld Destroyer can save allies or himself caught by Dismember or Meat Hook with Astral Imprisonment.
Luna
* 
Shadow Dance prevents Luna from damaging Slark, and together with Silver Edge he can easily chase her or escape from her.
* Luna has no way to escape from 
Pounce's leash.
* For the same reasons, Slark makes a very powerful ally for Luna when they are in the same team.
Additional:
* Luna's lack of mobility and escape abilities makes her easily to gank for Slark.
* Shadow Dance helps avoid all the damage from Eclipse.
* For the same reasons, Slark makes a very powerful ally for Luna when they are in the same team.
Luna
* With Dust of Appearance, Luna will be able to use Eclipse on invisible heroes. Be mindful that Slark is exception because he'll be able to remove the debuff with 
Dark Pact.
Outworld Destroyer
* Outworld Destroyer can disrupt Slark's attacks with Astral Imprisonment either by banishing Slark or his target.
* Slark's low heathpool means he will die quickly to Arcane Orb if he is directly attacked by Outworld Destroyer
* Slark has low intelligence gain, making him easy to finish with Sanity's Eclipse if he tries to run with Shadow Dance
Additional:
* Arcane Orb deals pure damage, which ignores the armor granted from permanent agility stacks.
* Astral Imprisonment can disrupt any Pounce attempt by banishing the leashed ally.
* Slark's low mana pool makes him more susceptible to Sanity's Eclipse.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Outworld Destroyer
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.
Additional:
* Outworld Destroyer's pure damage from Arcane Orb is very effective at killing Troll Warlord quickly.
* Astral Imprisonment removes Troll Warlord from a fight for four seconds, minimizing his contribution to a teamfight, and potentially wasting over half of Battle Trance's duration.
* Troll Warlord gains a measly 1 intelligence point per level, meaning Sanity's Eclipse is especially effective, often instantly killing him.
Luna
* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Additional:
* Lucent Beam interrupts Death Ward from a decent range.
* With Dust of Appearance, Eclipse kills Witch Doctor during Death Ward, even through 
Glimmer Cape.
Luna
* Moon Glaives can ignore certain abilities that either trigger on attack or give evasion under the condition that the heroes who have them are not primary targets. Examples include: Centaur Warrunner, Windranger, Phantom Assassin, Hoodwink etc.
Luna
* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: Monkey King, Alchemist, Timbersaw.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Enchantress has pitiful HP, even more pitiful than Luna, so Lucent Beam and Eclipse will often harass and/or kill her through her Untouchable.
* With Moon Glaives, Luna can clear Enchantress's creep wave efficiently.
Additional:
* Though Enchantress's 
Untouchable can greatly reduce Luna's attack speed, and can go through any form of Spell Immunity, she has a pitiful HP so Lucent Beam and Eclipse can kill her very quickly.
* Moon Glaives allows Luna to clear Enchantress's creeps very efficiently.
Luna
* Heroes with damage-over-time abilities easily allow Bristleback to turn his back in order to proc 
Bristleback continuously and to massively reduce to damage dealt to him: Arc Warden, 
Venomancer, Luna.
Additional:
* 
Quill Spray and Bristleback harass Luna more efficiently than she does with Lucent Beam.
* Bristleback helps return a lot of damage to Luna’s team if she uses her nukes on him and he has his back to her.
* 
Viscous Nasal Goo and 
Warpath are enough to outrun a speedy Luna.
* Bristleback tends to be a frequent carrier of 
Crimson Guard and 
Eternal Shroud, which are good protection from Moon Glaives and Eclipse.
* For the same reasons, Bristleback makes a very powerful ally for Luna when they are in the same team.
Outworld Destroyer
* Outworld Destroyer's high burst damage is not negated by Bristleback's passive. So, even if Bristleback turns his back on Outworld, he can decimate Bristleback quickly.
* If Bristleback attempts to flee, or tries to close the gap, Outworld can banish him with Astral Imprisonment, both reducing Bristlebacks much needed mana and allowing Outworld to move in front of him, forcing him to take the full damage from his spells. This will also allow Outworld to land a devasting Sanity's Eclipse, without it being reduced by Bristleback's passive.
Luna
* Heroes who cannot fight back during Arena of Blood in the early and mid game: Abaddon, Anti-Mage, 
Broodmother, Luna, Sniper, Troll Warlord, Weaver, 
Clinkz.
Outworld Destroyer
* Arcane Orb's pure damage ignores Mars' Bulwark.
* Astral Imprisonment can be used to stop Mars from being disruptive or save allies from his abilities.
* Sanity's Eclipse deals high damage to Mars, due to his low intelligence pool.
Outworld Destroyer
* Any heroes with high intelligence, such as Invoker and Pugna.
Outworld Destroyer
* Astral Imprisonment allows Outworld Destroyer to save himself or ally from Invoker's combo, or remove Invoker from a fight temporarily.
* Arcane Orb's pure damage will deal a lot of damage against Invoker's mediocre strength gain.
* E.M.P. is useless against Outworld Destroyer by activating 
Equilibrium.
* However, be aware that Sanity's Eclipse will most likely not deal any damage at all, due to Invoker's high intelligence gain compared to Outworld Destroyer's.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Moon Glaives and Lunar Blessing help Luna quickly kill Nature's Prophet's treants.
* Luna can easily cancel Teleportation with her Lucent Beam.
* Even though Nature's Prophet can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.
Additional:
* Moon Glaives and Lunar Blessing help Luna quickly kill Nature's Prophet's treants. Aghanim's Shard upgraded Moon Glaives can also reduce damage Nature's Prophet will inflict on Luna while they are active.
* Luna can easily cancel Teleportation with her Lucent Beam.
* Even though Nature's Prophet can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Nature's Prophet to her and her team.
Luna
* Escape-type carries: Slark, Storm Spirit, Weaver.
Outworld Destroyer
* Outworld Destroyer has a huge damage from Arcane Orb, which is why in a 1 on 1 skirmish Storm Spirit simply cannot defeat him in damage. Since Outworld Destroyer will stop gank Storm Spirit with his Astral Imprisonment, and then kill him if he decides to fight
Additional:
* Outworld Destroyer has a huge damage from Arcane Orb, which is why in a 1 on 1 skirmish Storm Spirit simply cannot defeat him in damage. Since Outworld Destroyer will stop gank Storm Spirit with his Astral Imprisonment, and then kill him if he decides to fight
Outworld Destroyer
* Any heroes with high intelligence, such as Invoker and Pugna.
Luna
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* 
Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* 
Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet their ablities have very high mana costs, Luna does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Additional:
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet have very high mana costs, she does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Luna
* All assassin-type carries in a one against one situation: Meepo, Phantom Assassin, Riki, Ursa. Luna's only chances are that she buys Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.
Luna
* Luna can push very fast with Moon Glaives, which is something Riki cannot deal with well.
* Luna is naturally very fast, making it hard for Riki to trap her in Smoke Cloud.
* Even though Riki can evade Eclipse with his invisibility, smart Luna will always buy Dust of Appearance, providing vision on Riki to her allies and herself.
Additional:
* Luna can push very fast with Moon Glaives, which is something Riki cannot deal with well.
* Luna is naturally very fast, making it hard for Riki to trap her in Smoke Cloud.
* Even though Riki can evade Eclipse with his invisibility, smart Luna will always buy Dust of Appearance, providing vision on Riki to her allies and herself.
Outworld Destroyer
* Heroes with built-in spell immunity can become immune to all of Outworld Destroyer's spells: Lifestealer's Rage and Juggernaut's Blade Fury.
Luna
* Although Lifestealer can avoid Eclipse with Rage and 
Infest, Luna's physical damage can be enough to deal with him.
* Manta Style is a common pick on Luna, which can help her dispel slows from 
Ghoul Frenzy and 
Open Wounds. In addition, Lifestealer is not good against illusions created by Manta Style.
Additional:
* Although Lifestealer can avoid Eclipse with Rage and Infest, Luna's physical damage from Moon Glaives and Lunar Blessing can be enough to deal with him.
* Manta Style is a common pick on Luna, which can help her dispel slows from Ghoul Frenzy and Open Wounds. In addition, Lifestealer is not good against illusions created by Manta Style.
* Even though Aghanim's Scepter upgraded Infest can disarm Luna and allow Lifestealer to attack her from inside even if she is spell immune, Luna can easily counter this with Linken's Sphere, which is a common item on Luna.
Luna
* A couple of nukers and disablers on the same lane can finish a squishy Luna efficiently despite a teammate's assistance: Sven + Shadow Shaman.
Luna
* Luna's high magical damage burst from Lucent Beam and Eclipse can take advantage of Shadow Shaman's low health and strength gain.
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Shadow Shaman while he is channeling Shackles.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetively stun Shadow Shaman, and can even discourage him from even trying to use Shackles.
* Luna is a natural Black King Bar wielder, and almost none of Shadow Shaman's spells can bypass spell immunity, except for 
Mass Serpent Ward.
* Bear in mind, however, that if Shadow Shaman gets a jump on Luna first, he will be able to use 
Hex to disable Luna and burst her down before she can use Black King Bar, Lucent Beam or Eclipse. In addition, Moon Glaives cannot bounce on Mass Serpent Wards at all.
Additional:
* Luna's high magical damage burst from Lucent Beam and Eclipse can take advantage of Shadow Shaman's low health and strength gain.
* Without Black King Bar, Luna's Lucent Beam and 0.25 Eclipse Mini-stun talent for Eclipse can be used to disable Shadow Shaman while he is channeling Shackles.
* Aghanim's Scepter upgraded Eclipse combined with 0.25 Eclipse Mini-stun can repetitively stun Shadow Shaman, and can even discourage him from even trying to use Shackles.
* Luna is a natural Black King Bar wielder, and almost none of Shadow Shaman's spells can bypass spell immunity, except for Mass Serpent Ward.
* Bear in mind, however, that if Shadow Shaman gets a jump on Luna first, he will be able to use Hex to disable Luna and burst her down before she can use Black King Bar, Lucent Beam or Eclipse. In addition, Moon Glaives cannot bounce on Mass Serpent Wards at all.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Luna's Moon Glaives allow her to clear Arc Warden's 
Tempest Double.
* Luna's short range and fast movement speed allow her to fight Arc Warden inside his 
Magnetic Field.
Additional:
* Luna's Moon Glaives allow her to clear Arc Warden's Tempest Double.
* Luna's short range and fast movement speed allow her to fight Arc Warden inside his Magnetic Field.
Luna
* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.
Outworld Destroyer
* Astral Imprisonment wastes Borrowed Time's duration.
* Outworld Destroyer's Sanity's Eclipse can kill Abaddon before Borrowed Time triggers due to the lack of intelligence for Abaddon.
Outworld Destroyer
* 
Tinker's 
Laser is useful against Outworld Destroyer, as the blind prevents him from landing Arcane Orbs.
Luna
* Even though Luna has a hard time laning against Tinker because of 
Heat-Seeking Missile and Laser, she can win against him in late game once she buys Black King Bar, as none of Tinker's spells can bypass spell immunity.
* Lucent Beam and 0.25 Eclipse Lucent Mini-stun talent for Eclipse can be used to cancel 
Rearm and prevent Tinker's escape attempts with 
Boots of Travel. Luna can also use Lucent Beam and Eclipse if she is blinded with Laser.
* An ill-timed and ill-positioned Blink Dagger will make Tinker a very easy target for Luna's Eclipse that can quickly tear him to shreds. This can get even better if Luna buys Aghanim's Scepter and combines it with 0.25 Eclipse Lucent Mini-stun talent for Eclipse.
* However, Luna needs to approach Tinker carefully, as Tinker is a natural 
Scythe of Vyse wielder, and if he gets a jump on Luna first, he will be able to use it to disable and burst down Luna before she can use Black King Bar, Lucent Beam or Eclipse.
Additional:
* Even though Luna has a hard time laning against Tinker because of Heat-Seeking Missile and Laser, she can win against him in late game once she buys Black King Bar, as none of Tinker's spells can bypass spell immunity.
* Lucent Beam and 0.25 Eclipse Lucent Mini-stun talent for Eclipse can be used to cancel Rearm and prevent Tinker's escape attempts with Boots of Travel. Luna can also use Lucent Beam and Eclipse if she is blinded with Laser.
* An ill-timed and ill-positioned Blink Dagger will make Tinker a very easy target for Luna's Eclipse that can quickly tear him to shreds. This can get even better if Luna buys Aghanim's Scepter and combines it with 0.25 Eclipse Lucent Mini-stun talent for Eclipse.
* However, Luna needs to approach Tinker carefully, as Tinker is a natural Scythe of Vyse wielder, and if he gets a jump on Luna first, he will be able to use it to disable and burst down Luna before she can use Black King Bar, Lucent Beam or Eclipse.
Luna
* Heroes that create illusions: Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden) can cause Eclipse to strike the illusions/summons unintentionally. However, in many cases Moon Glaives can resolve this issue and eliminate them before activating Eclipse, but that will require lots of farming for right-click items.
Luna
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).
Luna
* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* 
Dual Breath and 
Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use Eclipse by casting 
Ice Path on Luna.
* Aghanim's Scepter upgraded 
Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.
Additional:
* Even though Luna can easily kill Jakiro in few strikes, he can also do the same to her is she is not careful.
* Dual Breath and Liquid Fire allow Jakiro to harass Luna more efficiently than she can harass Jakiro with her Lucent Beam.
* Jakiro can save his allies from Luna during her attempts to use Eclipse by casting Ice Path on Luna.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can make it very hard for Luna to be in teamfights without suffering too many damage.
* For the same reasons, Jakiro makes a very powerful ally for Luna when they are in the same team.
Outworld Destroyer
* Astral Imprisonment can be used to protect allies from Jakiro's various abilities, It can also be cast on Jakiro to break his combos (Macropyre into Ice path into Dual Breath), while at the same time, stealing his much needed mana.
* Aghanim's Shard upgraded Astral Imprisonment allows Outworld Destroyer and his allies to move while imprisoned, which allows them to leave the area of Jakiro's abilities.
* As Outworld Destroyer is prone to buying Meteor Hammer, he can combine it with Astral Imprisonment and Arcane Orb's high pure damage that can quickly decimate Jakiro, And unlike most heroes, Outworld doesn't particularly care who he targets.
* Outworld is also a common Black King's Bar carrier, and Jakiro's only tool to counter it is the Aghanim's Scepter upgraded Macropyre
Outworld Destroyer
* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed Sanity's Eclipse and/or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used Black King Bar beforehand.
Additional:
* Outworld Destroyer's high intelligence makes him a good target for 
Mind Flare.
* If timed correctly, 
Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.
Luna
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy 
Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though 
Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Additional:
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Luna
* A couple of nukers and disablers on the same lane can finish a squishy Luna efficiently despite a teammate's assistance: Sven + Shadow Shaman.
Outworld Destroyer
* Tanky melee heroes that can easily be kited, which allows Outworld Destroyer to deal heavy damage with Arcane Orb from a distance: Sven, Underlord, Bristleback.
Luna
* All assassin-type carries in a one against one situation: Meepo, Phantom Assassin, Riki, Ursa. Luna's only chances are that she buys Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.
Outworld Destroyer
* Ursa struggles against heroes with strong (and especially undispellable) disables (Disruptor, Puck, Shadow Demon, Outworld Destroyer and etc).
Luna
*
Telekinesis allows Rubick and his team to coordinate a gank on Luna early on. And just like 
Aghanim's Shard upgraded 
Dismember, 
Aghanim's Shard upgraded 
Telekinesis can also allow Rubick to save an allied hero from being killed by Eclipse.
Fade Bolt allows Rubick to harass Luna on lane and weaken her attack damage early on.
Lucent Beam and 
Eclipse are very useful for Rubick to steal with 
Spell Steal, Luna's only way to counter this is with 
Aghanim's Shard upgraded 
Moon Glaives. Rubick can also use them from further distances than Luna thanks to 
Arcane Supremacy that increases his cast range and when he gets 
Aghanim's Scepter.
Lucent Beam is a solid magic nuke with a stun.
Aghanim's Shard upgraded 
Lucent Beam gives Rubick bonus damage whenever he uses it
Eclipse can output massive damage if casted by 
Rubick.
Eclipse since 
Luna has only two cast abilities.
Aghanim's Scepter greatly increase the effectiveness of the ability, with more damage as well as extended cast range.
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* Both,
* For the same reasons, Rubick makes a very powerful ally for Luna when they are in the same team.
Additional:
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*
*
* Rubick has a good chance to steal
*
* For the same reasons, Rubick also makes a good ally for Luna when they are in the same team.
Outworld Destroyer
* Rubick can use
Spell Steal to steal Astral Imprisonment, and if Rubick gets 
Aghanim's Scepter he gets 2 charges of it. This can overpower Outworld Destroyer in team fights.
* Rubick can also steal Sanity's Eclipse against Outworld Destroyer's teammates.