Medusa
* Silencer burns easily through her effective HP from 
Mana Shield, by taking away her intelligence.
* 
Arcane Curse punishes her repeatedly casting 
Mystic Snake to keep her mana pool high. He can force her to use 
Manta Style before he has cast 
Global Silence and 
Medusa usually does not want to build 
Black King Bar.
Abaddon
* Heroes that have long silences, such as 
Night Stalker and 
Silencer, will prevent Abaddon from saving his allies effectively and disable the active component of Borrowed Time.
Medusa
* He can use either his own or his double's 
Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + 
Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double 
Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.
Medusa
* Phantom Lancer with 
Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* 
Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.
Medusa
* E.M.P. allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* 
E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* 
Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* 
Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.
Medusa
* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, 
Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away all of Medusa's mana.
Additional:
* 
Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.
Abaddon
* 
Astral Imprisonment wastes Borrowed Time's duration.
* Outworld Destroyer's 
Sanity's Eclipse can kill Abaddon before Borrowed Time triggers due to the lack of intelligence for Abaddon.
Abaddon
* Ice Blast nullifies 
Borrowed Time's and 
Mist Coil's healing.
Additional:
* 
Ice Blast's nullifies Abaddon healing from Borrowed Time and Mist Coil and it is not dispelled by Aphotic Shield.
Medusa
* With 
Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
* He can deal a huge amount of damage through 
Cloak and Dagger, even through Mana Shield.
Abaddon
* Because 
Poison Attack has no cooldown, 
Aphotic Shield is ineffective as a hard dispel.
* 
Nethertoxin prevents Borrowed Time from activating passively and blocks 
Curse of Avernus
Abaddon
* Dispel Magic can remove Abaddon's Aphotic Shield or Curse of Avernus on an allied hero.
* Cyclone's lengthy duration wastes much of Borrowed Time's duration.
Additional:
* {U:Storm} can use 
Cyclone on Abaddon when he activates Borrowed Time, wasting its duration.
* 
Drunken Brawler and 
Thunder Clap hinder Abaddon from applying Curse of Avernus' silence on him.
Medusa
* Axe can take advantage of Medusa's awfully low HP to insta-kill her with 
Culling Blade, making it extremely difficult for her to farm for items to compensate for the lack of strength during early and mid-game while Axe is continuously harassing around.
Abaddon
* Culling Blade ignores Borrowed Time should Abaddon's health falls under the threshold.
* Aphotic Shield does nothing against Berserkers Call and has to be used constantly to remove the very small mana cost of Battle Hunger in lane.
Additional:
* Culling Blade's instant kill is not prevented by Borrowed Time should Abaddon's health falls below the threshold.
Medusa
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.
Medusa
* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Additional:
* Ursa's status resistance from 
Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with 
Fury Swipes easily against her Mana Shield in a prolonged team match.
Abaddon
* Shadow Demon with an 
Aghanim's Scepter will use 
Demonic Purge to disable Curse of Avernus and the passive component of Borrowed Time. If this is combined with a silence, Borrowed Time will not trigger at all.
* Even without Aghanim's Scepter, he can still waste Borrowed Time with 
Disruption. Curse of Avernus fully works on illusions, turning the passive ability against him.
Medusa
* Medusa is a fairly immobile hero that deals damage around her with 
Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her 
Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Additional:
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.
Medusa
* With 
Static Link, Razor can effectively make Medusa useless in teamfights by reducing her main damage output. It can, however, be blocked by a 
Linken's Sphere.
* 
Plasma Field allows Razor to get on top of Medusa, slowing her already slow movement speed to a mere crawl.
* 
Eye of the Storm capitilizes on Medusa's low armor and causes her to be very vulnerable, even through Mana Shield.
Abaddon
* Abaddon can be killed without triggering his ultimate Borrowed Time due to the break applied by 
Sharpshooter.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: 
Riki, 
Naga Siren, 
Terrorblade, 
Juggernaut, 
Spectre, 
Slark.
Abaddon
* Reflection will cause Abaddon to be afflicted by his own Curse of Avernus, silencing and slowing him. The reflection is also hard to avoid, as it cannot be killed, only dispelled.
Abaddon
* Heroes who can negate effects of Sunder: 
Faceless Void's 
Time Walk, 
Weaver's 
Time Lapse, 
Broodmother's 
Insatiable Hunger, 
Abaddon's Borrowed Time and 
Troll Warlord's 
Battle Trance can nullify Sunder.
Medusa
* 
Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* 
Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* 
Arena Of Blood blocks Medusa's attacks from outside the arena.
Abaddon
* Heroes who cannot fight back during Arena of Blood in the early and mid game: Abaddon, 
Anti-Mage, Broodmother, 
Luna, 
Sniper, Troll Warlord, Weaver, 
Clinkz.
Medusa
* Medusa's Stone Gaze forces Mars to choose between getting petrified, or turning his vulnerable back on Medusa.
Abaddon
* Heroes that have long silences, such as Night Stalker and Silencer, will prevent Abaddon from saving his allies effectively and disable the active component of Borrowed Time.
Medusa
* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Additional:
* 
Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's 
Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Abaddon
* 
Nyx Assassin might not kill Abaddon with his nuke, but a support Abaddon will struggle to protect an ally from him.
Abaddon
* 
Impale and Spiked Carapace stun can be instantly dispelled by Aphotic Shield.
* Abaddon can use Borrowed Time and easily heal for the duration of Borrowed Time by Nyx's burst damage.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Abaddon
* 
Song of the Siren completely wastes Abaddon Borrowed Time while keeping him in place.
* Naga Siren is able to simply dispel Abaddon's Curse of Avernus with 
Mirror Image before getting hit 4 times consecutively.
* Although Naga Siren's illusions can be easily destroyed by Aphotic Shield, Naga Siren can resolve that issue easily by purchasing 
Heart of Tarrasque to drastically increase her durability. Plus, the said item makes Naga Siren harder to be distinguished from her illusions.
Medusa
* Medusa's Split Shot and Mystic Snake combined with 
Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Additional:
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: 
Tidehunter, 
Bristleback, 
Slardar.
Medusa
* Heroes with extremely slow movement speed will cripple against Solar Bind: Medusa, 
Viper
Additional:
* 
Will-O-Wisp will keep Medusa busy after she got hit by 
Blinding Light.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift particularly removes 1 intelligence point per hit, thus lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Additional:
* Medusa is especially vulnerable to 
Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* 
Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.
Abaddon
* Heroes that can deny Slark early kills will prevent him from snowballing: 
Dazzle, Abaddon.
Medusa
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating and landing an effective 
Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult. Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.
Abaddon
* Borrowed Time can give Abaddon a second chance after a Black Hole combo.
* Aphotic Shield can be used to save allies or Abaddon himself from Malefice.
* Abaddon can easily heal himself as well as his allies during a team fight, especially with Aghanim's Scepter upgraded Borrowed Time.
Medusa
* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.
Abaddon
* Borrowed Time makes Abaddon nearly impossible to gank.
* Aphotic Shield and Mist Coil prevents Bloodseeker from gaining his Thirst bonuses.
Additional:
* If 
Rupture is used on Abaddon, Abaddon can use Borrowed Time and easily heal for the duration of Borrowed Time by simply moving.
Medusa
* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.
Abaddon
* If he isn't broken (break), Abaddon can use Borrowed Time to waste Legion Commander's 
Duel, As Borrowed Time has a shorter cooldown, Legion Commander can't win duels, effectively reducing her targets by one, Duel also means that Borrowed Time heals Abaddon for the duration of the duel, as Legion can't stop attacking.
Additional:
* Aphotic Shield and Mist Coil makes it hard for Legion Commander to kill Abaddon's teammates in Duels.
* Borrowed Time makes Abaddon nearly impossible to kill in Duels, and often replenishes much of his health because Legion Commander cannot manually stop attacking during Duels.
Medusa
* Medusa's Split Shot can easily kill Chen's creeps.
* Mystic Snake can quickly kill Chen's creeps and deal intense damage for every killed creep while also draining their mana with each bounce. Aghanim's Scepter upgraded Mystic Snake can also disable both, Chen and his creeps upon impact.
* Mana Shield will make it impossible for Chen to burst down Medusa.
* Stone Gaze can disable Chen from using 
Hand of God to save himself or his allies.
Abaddon
* Aphotic Shield can nullify Chen's combo, while clearing Chen's creeps simultaneously.
Medusa
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with 
Lucent Beam.
* Medusa can survive 
Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Abaddon
* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, 
Clockwerk, 
Drow Ranger, Abaddon, Faceless Void, Weaver, 
Outworld Destroyer.
Medusa
* Heroes with Linken's Sphere as core item: Weaver, 
Morphling, Medusa.
Abaddon
* Aphotic Shield effectively nullifies Primal Roar's single-target initiation on allies.
* Even being initiated by Primal Roar, Borrowed Time can make Abaddon extremely difficult to kill.
Additional:
* 
Primal Roar can be instantly dispelled by Aphotic Shield.
* The debuffs from 
Wild Axes and 
Poison from 
Call of the Wild: Boar can also be dispelled by Aphotic Shield.
Medusa
* Mana Shield can tank most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.
Abaddon
* Heroes who possess abilities that can save targets from being killed by Reaper's Scythe: Abaddon, 
Bane, Outworld Destroyer, 
Shadow Demon, 
Omniknight, etc.
Additional:
* If he isn't silenced, Abaddon can use Borrowed Time to escape 
Reaper's Scythe during the delay.
Medusa
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: 
Sven, Omniknight, 
Enigma, Luna, Naga Siren, 
Mars, 
Jakiro, 
Venomancer, 
Elder Titan, Faceless Void, 
Rubick, 
Keeper of the Light, 
Pugna, 
Invoker, Spectre, 
Alchemist, 
Treant Protector, 
Lina, 
Oracle, 
Zeus, 
Shadow Shaman, 
Phoenix, 
Razor, 
Huskar, 
Batrider, 
Kunkka, Tidehunter, 
Wraith King, 
Sand King, Medusa, 
Dawnbreaker.
Abaddon
* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, 
Dragon Knight, Night Stalker, Viper.
Medusa
* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.
Abaddon
* Aphotic Shield and Borrowed Time can both dispel Flaming Lasso.
Additional:
* 
Sticky Napalm, 
Flaming Lasso, and 
Flamebreak can all be instantly dispelled by Aphotic Shield.
* 
Firefly will continuously heal Abaddon under Borrowed Time.
Abaddon
* Aphotic Shield prevents damage and dispels the slow from Snapfire's 
Mortimer Kisses.
* Borrowed Time allows Abaddon to gain HP during Snapfire's Mortimer Kisses.
Abaddon
* Aphotic Shield makes it less likely for allies to be killed by mines.
* Because they explode in very short intervals, a stack of 
Remote Mines will always trigger Borrowed Time, making them impossible to kill Abaddon unless his resistances are lowered enough or Abaddon is affected by Break.
* Abaddon can easily dispel the long-lasting root of 
Stasis Trap on himself and on an ally, while at the same also providing protection against the other mines' damage.
Additional:
* Borrowed Time's automatic activation will help Abaddon survive a field of Proximity Mines or a Blast Off combo. However, the damage from a single mine can kill him if his HP is low enough.
* Aphotic Shield's can easily break Techies' Etheral Blade combo.
Abaddon
* Aphotic Shield dispels Thunder Strike.
* Mist Coil can be used to heal an ally trapped by Static Storm-Kinetic Field combo.
* Borrowed Time makes Abaddon nearly impossible to gank.
Abaddon
* Abaddon can remove Sacred Arrow's stun from his teammates with Aphotic Shield, or remove it from himself with Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.
Additional:
* 
Sacred Arrow can be instantly dispelled by Aphotic Shield.
Abaddon
* Abaddon can activate Borrowed Time to dispel Dismember; breaking the disable and potentially allowing Abaddon to escape.
* Aphotic Shield can be cast on an ally to dispel the stun of Dismember, which can make kills difficult to secure, given that Dismember is Pudge's only reliable disable.
* Pudge lacks a mobility without a 
Blink Dagger, causing him to be easily chased with Curse of Avernus. The silence also prevents him from toggling off his Rot.
Abaddon
* Aphotic Shield is a strong dispel, meaning it can save allies from Earth Spirit's stun, slow, silence, and Magnetize.
* Borrowed Time makes it nearly impossible for Earth Spirit to kill Abaddon.
Medusa
* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.
Medusa
* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces 
Rage, wasting its cooldown and making Lifestealer unable to fight.
Abaddon
* Mist Coil and Aphotic Shield enable Abaddon to keep an ally alive during Chronosphere.
* Borrowed Time prevents Faceless Void from killing Abaddon during his Chronosphere.
Abaddon
* 
Exorcism will continuously heal Abaddon under Borrowed Time, and cannot be turned off.
* {Ability ID:Spirit Siphon|Death Prophet} will continuously heal Abaddon under Borrowed Time, for a percentage of his maximum health.
Abaddon
* Aphotic Shield removes silences, slows and stuns, possibly foiling a full-duration Mystic Flare.
* Borrowed Time makes it impossible to burst Abaddon down, even healing him up due to Mystic Flare's damage.
Medusa
* If Medusa activates Stone Gaze before Spirit Breaker reaches her with Charge of Darkness, the charge will inevitably fail.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation.
Abaddon
* Borrowed Time mitigates the damage by Pierce the Veil for most of its duration.
* Muerta has no control over Gunslinger, making her one of the best heroes for Abaddon to regenerate from via Borrowed Time.
Medusa
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to fight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalize on his commitment in a fight.
Additional:
* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Abaddon
* Borrowed Time & Aphotic Shield can dispel Venomous Gale and Poison Sting.
Medusa
* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.
Medusa
* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.
Medusa
* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake
Abaddon
* Abaddon could punish Chaos Knight for using his Phantasm and Reality Rift combo on him with Aphotic Shield. Additionally, it provides extra protection against Chaos Knight's potential to take Abaddon down quickly.
* Furthermore, Abaddon's Borrowed Time makes it utterly impossible to burst Abaddon down, effectively reducing the amount of targets Chaos Knight can threaten by 1 for the entire game.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.
Abaddon
* Abaddon can cast Aphotic Shield on any of his allies to immediately dispel Corrosive Haze and/or the stun and the slow components of Slithereen Crush.
* All of Slardar's debuffs are also removed if Abaddon's Borrowed Time triggers.
Abaddon
* 
Doom will make Abaddon unable to use Mist Coil, Aphotic Shield, and the active component of Borrowed Time, also upgraded with Aghanim's Scepter can break Curse of Avernus and the passive component of Borrowed Time ,which means his allies could be easily disabled or killed.
Medusa
* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.
Abaddon
* Heroes with the ability to heal allies, or those with good defensive abilities: 
Chen, Dazzle, 
Io, Oracle, Omniknight, 
Witch Doctor, 
Winter Wyvern, Abaddon, etc.
Abaddon
* Clockwerk lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Clockwerk finishes his initiation. Additionally, Clockwerk hates buying 
Dagon and 
Ethereal Blade, which are the only itmes that can help him deal with heroes who can recover themselves and turn the fight around to their advantage: Faceless Void, Terrorblade, 
Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, 
Lifestealer.
Abaddon
* Heroes that deal damage over time will also fail to bring down Abaddon and his allies, such as Huskar, Venomancer, or Phoenix.
Abaddon
* In general, heroes that deal burst in multiple instances will trigger Borrowed Time and heal Abaddon for a large amount, such as 
Skywrath Mage, 
Techies, Juggernaut, Shadow Shaman, or 
Ogre Magi.
Abaddon
* Abaddon with Aphotic Shield and Borrowed Time
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with 
Life Break
* Juggernaut with 
Blade Fury
* 
Legion Commander with 
Press the Attack
* Lifestealer with Rage and 
Infest
* Naga Siren with Mirror Image
* Omniknight with 
Heavenly Grace
* Oracle with 
Fortune's End and 
False Promise
* 
Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with 
Kraken Shell when damage received reaches the threshold.
Abaddon
* Omniknight can dispel Hex or Shackles with Heavenly Grace. He can also heal teammates which you disabled. The same goes to Abaddon's Aphotic Shield .
Medusa
* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: 
Axe, Enigma, 
Vengeful Spirit, 
Doom, Bane, 
Beastmaster, 
Pudge, Medusa, 
Warlock.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Medusa
* Heroes with cleave or multi-target attacks can quickly take on Familiars and reduce Visage's firepower like 
Gyrocopter, Kunkka, 
Magnus and Medusa.
Additional:
* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.
Medusa
* Hard carries who just want to farm and be left alone will not appreciate Primal Beast, heroes such as Medusa, Drow Ranger...
Abaddon
* Borrowed Time allows him to both exit his stuns prematurely and turn Trample into healing for himself. His Aghanim Scepter only prevents the automation of the spell, Abaddon himself can still manually activate it.
* Aphotic Shield will immediately debuff any stuns Primal Beast has put on allies but won't stop him from being stunned if casted on Abaddon.
Abaddon
* Lina is a common 
Eul's Scepter of Divinity carrier which can waste some duration of Borrowed Time and following up with 
Laguna Blade if timed correctly.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Abaddon
* Both 
Lion's 
Finger of Death and Lina's Laguna Blade have a 0.25 second delay before the damage is dealt.
Medusa
* Medusa lacks mobility or escape mechanisms. 
Earth Spike and 
Hex can neutralize her strong damage potential and allow for Lion's team to focus her down.
* In addition to easily breaking her commonly bought Linken's Sphere with its low cooldown, 
Mana Drain can quickly drain her Mana Shield, making her far less tanky.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.
Abaddon
* Aphotic Shield applies strong dispel on targeted allies, while Borrowed Time does the same on Abaddon himself upon both casts (manually or automatically), removing disables, such as Earth Spike and Hex.
* Abaddon may offer survivability to Lion's nuke power by shielding and healing allies and himself.
* Lack of inner escape and defensive mechanisms increases Curse of Avernus effectiveness, since it slows per stack (applied upon auto attacking), and silences when it reaches the maximum stack.
Medusa
* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and Anti-Mage.
Abaddon
* Heroes that can purge his slow and disables are very difficult to go on and their team: Abaddon, Oracle.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Abaddon
* In general, heroes that deal burst in multiple instances will trigger Borrowed Time and heal Abaddon for a large amount, such as Skywrath Mage, Techies, Juggernaut, Shadow Shaman, or Ogre Magi.
Medusa
* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* 
Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.
Abaddon
* Aphotic Shield applies a strong dispel on the allied target and can be used to remove both Fiend's Grip & Nightmare.
* Borrowed Time applies a strong dispel on Abaddon and can instantly remove both Fiend's Grip & Nightmare when activated.
* Bane, when caught by Curse of Avernus struggles to escape because of his innately low mobility.
Additional:
* 
Nightmare and Fiend's Grip can be instantly dispelled by Aphotic Shield.
* Bane lacks mobility, therefore becoming helpless when silenced by Curse of Avernus.
Medusa
* 
Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* 
Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.
Abaddon
* Huskar's damage over time gives Abaddon the opportunity to shield and heal his allies.
* Borrowed Time also makes Abaddon a hard support to gank, thus negating Huskar's early game dominance.
Medusa
* Anti-Mage easily destroys
Mana Shield with Mana Break, especially once he has 
Manta Style.
Stone Gaze with Blink, and can reinitiate after its duration is over.
Mana Break burns Medusa's mana easily, especially when coupled with a 
Manta Style.
Blink, burning her mana or forcing her to use Stone Gaze.
Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.
* Anti-Mage effectively avoids
Additional:
*
* Can easily initiate on Medusa with
*
Abaddon
* Mana Break drains Abaddon's mana, preventing him from using
Aphotic Shield to zone out enemies in lane.
Aphotic Shield and 
Mist Coil.
* Counterspell decreases the amount of damage received from