Medusa
* 
Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's 
Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with 
Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive 
Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious 
Stone Gaze.
* Mana Burn quickly destroys 
Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from 
Mystic Snake and Split Shot can trigger Spiked Carapace.
* 
Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Dawnbreaker
* Spiked Carapace can stop Dawnbreaker's Solar Guardian which will eliminate her global presence and limits her movement around the map.
Additional:
* Spiked Carapace interrupts 
Starbreaker before Dawnbreaker has her Aghanim's Shard, as well as 
Solar Guardian during the initial channel, making her ineffective at joining and dealing damage in teamfights.
* The slow projectile and damage over time effect of 
Celestial Hammer makes it easy to stun Dawnbreaker if she attemps to engage or chase.
Dawnbreaker
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: 
Jakiro, 
Viper, 
Venomancer, 
Huskar, 
Ember Spirit, 
Dark Seer, 
Sand King, 
Doom, 
Dawnbreaker. However, this also means they are easily stunned.
Dawnbreaker
* Savage Roar interrupts Starbreaker.
* Dawnbreaker is a slow moving hero. Although tanky, Lone Druid can eventually wear her down with his better movement speed.
Medusa
* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, 
Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from Mana Shield fully while Broodmother can fit a 
Diffusal Blade to burn away all of Medusa's mana.
Additional:
* 
Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.
Medusa
* He can use either his own or his double's 
Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + 
Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double 
Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.
Medusa
* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* 
Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. He can force her to use 
Manta Style before he has cast 
Global Silence and Medusa usually does not want to build 
Black King Bar.
Dawnbreaker
* 
Gust can shut down most of Dawnbreaker's abilities, rendering her useless.
* 
Frost Arrows followed by a high attack speed, makes it hard for Dawnbreaker to escape.
Dawnbreaker
* 
Kinetic Field prevents Dawnbreaker from escaping with Celestial Hammer.
* Kinetic Field and 
Static Storm can pin down Dawnbreaker after she jumps in with Solar Guardian.
* 
Glimpse can force Dawnbreaker out of a fight right after she uses Solar Guardian.
Medusa
* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* 
Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.
Medusa
* Ursa's status resistance from 
Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with 
Fury Swipes easily against her Mana Shield in a prolonged team match.
Additional:
* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Medusa
* 
Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* 
Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.
Dawnbreaker
* 
Nethertoxin disables Dawnbreaker's 
Luminosity. Since she's a melee hero, she needs to close gap to attack and Nethertoxin will be bad for her since she cannot heal.
* 
Viper Strike and 
Poison Attack will severely slow her down and combined with Nethertoxin, it will be her death sentence (unless her Celestial Hammer or Solar Guardian are off cooldown). Besides that, chasing her down will be easy due to the slow.
Medusa
* With 
Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
* He can deal a huge amount of damage through 
Cloak and Dagger, even through Mana Shield.
Medusa
* With 
Static Link, Razor can effectively make Medusa useless in teamfights by reducing her main damage output. It can, however, be blocked by a 
Linken's Sphere.
* 
Plasma Field allows Razor to get on top of Medusa, slowing her already slow movement speed to a mere crawl.
* 
Eye of the Storm capitilizes on Medusa's low armor and causes her to be very vulnerable, even through Mana Shield.
Medusa
* E.M.P. allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* 
E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* 
Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* 
Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.
Medusa
* Anti-Mage easily destroys Mana Shield with Mana Break, especially once he has Manta Style.
* Anti-Mage effectively avoids Stone Gaze with Blink, and can reinitiate after its duration is over.
Additional:
* 
Mana Break burns Medusa's mana easily, especially when coupled with a Manta Style.
* Can easily initiate on Medusa with 
Blink, burning her mana or forcing her to use Stone Gaze.
* 
Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.
Medusa
* Medusa is especially vulnerable to 
Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* 
Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.
Additional:
* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift particularly removes 1 intelligence point per hit, thus lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Medusa
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.
Additional:
* Medusa is a fairly immobile hero that deals damage around her with Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: 
Tidehunter, 
Bristleback, 
Slardar.
Medusa
* Heroes who take a long time to become strong are in for a rough mid game, such as 
Outworld Destroyer, 
Magnus, Medusa, and 
Anti-Mage.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: 
Riki, 
Naga Siren, 
Terrorblade, 
Juggernaut, 
Spectre, 
Slark.
Medusa
* Heroes with extremely slow movement speed will cripple against Solar Bind: Medusa, Viper
Additional:
* 
Will-O-Wisp will keep Medusa busy after she got hit by 
Blinding Light.
Dawnbreaker
* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:
Lion, 
Crystal Maiden ,Venomancer etc.
Dawnbreaker
* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:Lion, Crystal Maiden ,Venomancer etc.
Dawnbreaker
* Heroes with channeling spells are very easy targets for Jakiro's abilities: Crystal Maiden, Dawnbreaker, 
Enigma, 
Pudge, 
Shadow Fiend, 
Shadow Shaman, 
Warlock.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Hard carries who just want to farm and be left alone will not appreciate Primal Beast, heroes such as Medusa, 
Drow Ranger...
Medusa
* Phantom Lancer with Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* 
Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.
Dawnbreaker
* Heroes with summoned units don't fare well against Dawnbreaker. (
Phantom Lancer ,
Beastmaster ,
Lycan).
Medusa
* Medusa's Split Shot can easily kill Chen's creeps.
* Mystic Snake can quickly kill Chen's creeps and deal intense damage for every killed creep while also draining their mana with each bounce. Aghanim's Scepter upgraded Mystic Snake can also disable both, Chen and his creeps upon impact.
* Mana Shield will make it impossible for Chen to burst down Medusa.
* Stone Gaze can disable Chen from using 
Hand of God to save himself or his allies.
Dawnbreaker
* Starbreaker can deal huge damage to Chen and clear waves of his creeps.
* Celestial Hammer can deal damage over time to both, Chen and his creeps, which may force Chen to use Hand of God prematurely.
* Solar Guardian allows Dawnbreaker to counter Chen's pushing attempts and to rejoin her team with Solar Guardian when they require it. Aghanim's Scepter upgraded Solar Guardian can also give Dawnbreaker's allies evasion while Dawnbreaker is airborne for it's duration, wasting much of 
Penitence's power.
Additional:
* Starbreaker can deal huge damage to Chen and clear waves of his creeps.
* Celestial Hammer can deal damage over time to both, Chen and his creeps, which may force Chen to use Hand of God prematurely.
* Solar Guardian allows Dawnbreaker to counter Chen's pushing attempts and to rejoin her team with Solar Guardian when they require it. Aghanim's Scepter upgraded Solar Guardian can also give Dawnbreaker's allies evasion while Dawnbreaker is airborne for it's duration, wasting much of Penitence's power.
Medusa
* If Medusa activates Stone Gaze before Spirit Breaker reaches her with Charge of Darkness, the charge will inevitably fail.
* Medusa has three ways to counter Spirit Breaker's Charge of Darkness: Stone Gaze can disable Spirit Breaker's Charge of Darkness if he faces Medusa directly. Aghanim's Scepter upgraded Mystic Snake can disable Spirit Breaker and cancel his Charge of Darkness if it hits him. And 
Cold Blooded provided by 
Aghanim's Shard that can cast a single-targeted Mystic Snake at Spirit Breaker if he uses Charge of Darkness on her.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation. And to make things worse, Spirit Breaker is not a common Diffusal Blade nor 
Disperser wielder to counter this problem at all.
* Overall, any attempt for Spirit Breaker to gank and kill Medusa will hurt him more than the other way around.
Dawnbreaker
* Solar Guardian can save an ally getting targeted and focused by Spirit Breaker.
Medusa
* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.
Dawnbreaker
* Solar Guardian can save allies who are being dueled and will interrupt her 
Duel initiation.
Medusa
* Any long duration disables that can pierce through both, Pierce The Veil and Black King Bar are devastating against Muerta: Enigma's 
Black Hole, Dawnbreaker's Solar Guardian, 
Axe's 
Berserker's Call, Naga Siren's Aghanim's Scepter upgraded 
Ensnare and 
Reel In from Aghanim's Scepter, Jakiro's Aghanim's Scepter upgraded 
Macropyre, 
Bane's Fiend's Grip, Pudge's 
Dismember, 
Batrider's 
Flaming Lasso, Beastmaster's 
Primal Roar, 
Grimstroke's 
Soulbind, Medusa's Stone Gaze, Magnus's 
Reverse Polarity.
Dawnbreaker
* Dawnbreaker can use Solar Guardian to help her team against Muerta whenever they are in distress against her, especially when trapped in the radius of the 
The Calling. Aghanim's Scepter upgraded Solar Guardian can also give Dawnbreaker's allies evasion against Muerta's attacks from 
Gunslinger while Dawnbreaker is airborne for it's duration.
* Solar Guardian and Starbreaker can disable Muerta even through both, 
Pierce the Veil and Black King Bar, though Starbreaker will not deal any damage to Muerta as it's damage output is physical instead of magical.
* Celestial Hammer and Solar Guardian deal magical damage which allows Dawnbreaker to fightback against Muerta whenever she has Pierce the Veil. Dawnbreaker can also buy 
Revenant's Brooch to attack Muerta through Pierce the Veil with Starbreaker.
* Dawnbreaker is also common Black King Bar wielder which allows her to protect herself against Muerta's abilities. Aghanim's Shard upgraded Starbreaker can also give Dawnbreaker debuff immunity against Muerta's abilities.
Medusa
* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake
Dawnbreaker
* Heroes with summoned units don't fare well against Dawnbreaker. (Phantom Lancer ,Beastmaster ,Lycan).
Medusa
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating and landing an effective Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult. Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.
Dawnbreaker
* Heroes who can clear the waves of Enigma's Eidolons: 
Lina, 
Luna, Dawnbreaker, Jakiro, Shadow Shaman, 
Death Prophet, 
Keeper of the Light, 
Invoker, 
Leshrac, 
Puck.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Medusa
* Medusa's Split Shot and Mystic Snake combined with 
Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of 
Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Additional:
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Dawnbreaker
* Dawnbreaker can easily clear waves of Naga Siren's illusions from 
Mirror Image with Starbreaker, Celestial Hammer and Solar Guardian.
* Aghanim's Shard upgraded Starbreaker will allow Dawnbreaker to dispel Ensnare and freely attack Naga Siren during Song of the Siren when combined with Black King Bar, a common item on Dawnbreaker.
* Solar Guardian allows Dawnbreaker to counter any attempts of Naga Siren and rejoin her team with Solar Guardian when they require it. Aghanim's Scepter upgraded Solar Guardian can also give Dawnbreaker's allies evasion while Dawnbreaker is airborne for it's duration, as Naga Siren mainly relies on direct attacks in order to deal damage.
Additional:
* Dawnbreaker can easily clear waves of Naga Siren's illusions from Mirror Image with Starbreaker, Celestial Hammer and Solar Guardian.
* Aghanim's Shard upgraded Starbreaker will allow Dawnbreaker to dispel Ensnare and freely attack Naga Siren during Song of the Siren when combined with Black King Bar, a common item on Dawnbreaker.
* Solar Guardian allows Dawnbreaker to counter any pushing attempts of Naga Siren and rejoin her team with Solar Guardian when they require it. Aghanim's Scepter upgraded Solar Guardian can also give Dawnbreaker's allies evasion while Dawnbreaker is airborne for it's duration, as Naga Siren mainly relies on direct attacks in order to deal damage. Solar Guardian can also be used after Naga Siren uses Song of the Siren near her allies to either escape from or counter-initiate against them.
Medusa
* Heroes with Linken's Sphere as core item: 
Weaver, 
Morphling, Medusa.
Dawnbreaker
* Heroes with summoned units don't fare well against Dawnbreaker. (Phantom Lancer ,Beastmaster ,Lycan).
Medusa
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: 
Sven, 
Omniknight, Enigma, Luna, Naga Siren, 
Mars, Jakiro, Venomancer, 
Elder Titan, 
Faceless Void, 
Rubick, Keeper of the Light, 
Pugna, Invoker, Spectre, 
Alchemist, 
Treant Protector, Lina, 
Oracle, 
Zeus, Shadow Shaman, 
Phoenix, 
Razor, Huskar, Batrider, 
Kunkka, Tidehunter, 
Wraith King, Sand King, Medusa, Dawnbreaker.
Dawnbreaker
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.
Medusa
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded 
Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's 
Arena of Blood, Jakiro's Macropyre, 
Dual Breath and 
Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's 
Light Strike Array, 
Broodmother's 
Spinner's Snare from Aghanim's Scepter, Elder Titan's 
Earth Splitter and 
Echo Stomp, Alchemist's 
Unstable Concoction and 
Acid Spray, 
Queen of Pain's 
Sonic Wave, Dark Seer's 
Wall of Replica and 
Vacuum, Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from Aghanim's Shard, 
Bloodseeker's 
Blood Rite, Enigma's Black Hole and 
Midnight Pulse, Shadow Fiend's 
Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, 
Ancient Apparition's 
Ice Blast, Sand King's 
Epicenter, 
Sand Storm and 
Burrowstrike, 
Gyrocopter's 
Call Down, Ember Spirit's 
Sleight of Fist, Death Prophet's 
Exorcism and 
Silence, 
Monkey King's 
Wukong's Command, Crystal Maiden's 
Freezing Field, 
Muerta's The Calling, Medusa's Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, 
Pangolier's 
Swashbuckle, Grimstroke's Soulbind, 
Ink Swell and 
Stroke of Fate, 
Earthshaker's 
Echo Slam and 
Fissure, Puck's 
Dream Coil and 
Waning Rift, 
Winter Wyvern's 
Winter's Curse, Magnus's Reverse Polarity.
Dawnbreaker
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.
Medusa
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, 
Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa, Warlock.
Dawnbreaker
* Heroes capable of perofrming interceptions who can anticipate and counter-initiate after Phantom Assassin blinks on them with Phantom Strike will often kill her than the other way around: Axe, Bane, Dawnbreaker, 
Centaur Warrunner, Luna, Medusa, Omniknight, Pudge, Razor, Terrorblade, 
Underlord.
Medusa
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Dawnbreaker
* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker, Muerta, 
Dazzle.
Medusa
* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.
Dawnbreaker
* Starbreaker and Celestial Hammer does high AoE damage which easily clears {U:Treant}, shutting down most of Nature's Prophets damage and pushing power.
* Dawnbreaker can teleport to deal with split-pushing Nature's Prophet and rejoin her team with Solar Guardian when they require it.
* Since Starbreaker clears trees in its path followed by a stun at the end Nature's Prophet will be unable to escape the dangerous situation by using 
Sprout on himself and teleporting away with either 
Teleportation or 
Town Portal Scroll.
Additional:
* Starbreaker and Celestial Hammer does high AoE damage which easily clears {U:Treant}, shutting down most of Nature's Prophets damage and pushing power.
* Dawnbreaker can teleport to deal with split-pushing Nature's Prophet and rejoin her team with Solar Guardian when they require it.
* Since Starbreaker clears trees in its path followed by a stun at the end Nature's Prophet will be unable to escape the dangerous situation by using Sprout on himself and teleporting away with either Teleportation or Town Portal Scroll.
Medusa
* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to fight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalize on his commitment in a fight.
Medusa
* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.
Medusa
* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.
Medusa
* Mana Shield can tank most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.
Medusa
* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.
Medusa
* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.
Medusa
* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.
Medusa
* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.
Dawnbreaker
* Heroes with channeling spells because Shadow Fiend has nothing to cancel channeling outside of Requiem of Souls: Bane, Enigma, Pudge, Shadow Shaman, Dawnbreaker, Warlock, Crystal Maiden.
Medusa
* 
Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* 
Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* Arena Of Blood blocks Medusa's attacks from outside the arena.
Medusa
* Medusa's Stone Gaze forces Mars to choose between getting petrified, or turning his vulnerable back on Medusa.
Dawnbreaker
* Solar Guardian can save allies caught inside Arena of Blood.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Dawnbreaker
* Luna can easily cancel channeling spells with 
Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy 
Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, 
Witch Doctor's 
Death Ward, Shadow Shaman's 
Shackles, Lion's 
Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's 
Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Medusa
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, which can cause Luna to struggle greatly in bursting down Medusa and force her to buy Diffusal Blade and it's upgrade Disperser.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Dawnbreaker
* Spectre has no innate disables or silence to stop any of Dawnbreaker's abilities
* Solar Guardian allows Dawnbreaker to quickly stand next to one of her allies, denying Spectre any of 
Desolate's bonus.
* Luminosity outheals the damage dealt by 
Dispersion.
Additional:
* Spectre has no innate disables or silence to stop any of Dawnbreaker's abilities
* Solar Guardian allows Dawnbreaker to quickly stand next to one of her allies, denying Spectre any of Desolate's bonus
* Luminosity outheals the damage dealt by Dispersion
Dawnbreaker
* 
Time Walk can easily avoid Dawnbreaker's abilities or to escape her gank attempts and backtrack any damage she deals.
* 
Time Dilation can prevent Dawnbreaker from using her abilities after initiating, and slowing her down severely.
* 
Time Lock combined with his high attack speed can lock Dawnbreaker in place, preventing her escape with Celestial Hammer.
* 
Chronosphere locks down Dawnbreaker in place right after she uses Solar Guardian.
* On the other hand, if Solar Guardian is cast beforehand from afar, it may discourage Faceless Void from casting Chronosphere in its location
Dawnbreaker
* Solar Guardian can heal allies that trapped inside Chronosphere.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Dawnbreaker
* Heroes who have channeling abilities because Terrorblade has no disables to cancel them at all besides 
Terror Wave from Aghanim's Scepter, and he does not like buying disabling items at all: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.
Medusa
* Axe can take advantage of Medusa's awfully low HP to insta-kill her with 
Culling Blade, making it extremely difficult for her to farm for items to compensate for the lack of strength during early and mid-game while Axe is continuously harassing around.
Medusa
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.
Dawnbreaker
* Being a strength hero with a high strength gain means 
Feast can give her a hard time,especially later in the game.
* However,Starbreaker's physical damage can control him in the laning phase.
Medusa
* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces 
Rage, wasting its cooldown and making Lifestealer unable to fight.
Medusa
*
Medusa lacks mobility or escape mechanisms. 
Earth Spike and 
Hex can neutralize her strong damage potential and allow for 
Lion's team to focus her down.
Mana Drain is a perfect ability to weaken Medusa's durability as it can quickly drain her 
Mana Shield, making her far less tanky. 
Mana Drain can also be used to restore mana of Lion's allies, which can nullify the mana steal from 
Mystic Snake.
Mana Drain, along with 
Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of 
Manta Style, like 
Medusa herself.
*
*
Dawnbreaker
* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:
Lion, 
Crystal Maiden ,
Venomancer etc.