* EMP allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* EMP is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.

* Invoker's numerous area-of-effect abilities can interrupt Primal Beast, especially while he is in the middle of a team fight, where Primal Beast thrives. (Tornado, Cold Snap, and Ice Wall all help to disable Primal Beast and control him from a distance.
* EMP disintegrates Primal Beast's low mana pool.
* However, Invoker is quite a slow paced hero and not particularly known for being survivable against a rampaging Primal Beast with Black King Bar.

* Level 4 Mana Burn burns of Medusa's mana every 5 seconds if Medusa only increases her mana pool with intelligence. Additionally, 70% of the Mana Burn damage gets mitigated by Mana Shield, burning even more mana.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* Medusa lacks mobility or escape mechanisms. Earth Spike and Hex can neutralize her strong damage potential and allow for Lion's team to focus her down.
* In addition to easily breaking her commonly bought Linken's Sphere with its low cooldown, Mana Drain can quickly drain her Mana Shield, making her far less tanky.

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* Silence can be used to interrupt Primal Beast while he is channeling Pulverize.
* Spirit Siphon can whittle down Primal Beast's health and can potentially heal back any burst damage he deals to her.
* Exorcism can shed Primal Beast's health down while he attempts to complete any skill combos during a fight with it active.

* With Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
* He can deal a huge amount of damage through Cloak and Dagger, even through Mana Shield.

* Anti-Mage easily destroys Mana Shield with Mana Break, especially once he has Manta Style.
* Anti-Mage effectively avoids Stone Gaze with Blink, and can reinitiate after its duration is over.
Additional:
* Mana Break burns Medusa's mana easily, especially when coupled with a Manta Style.
* Can easily initiate on Medusa with Blink, burning her mana or forcing her to use Stone Gaze.
* Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.

* He can use either his own or his double's Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.

* Ursa's status resistance from Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with Fury Swipes easily against her Mana Shield in a prolonged team match.
Additional:
* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.

* Oracle can negate and shut down Primal Beast simply with Fate's Edict, especially in the early game, as a majority of his damage-dealing spells are magic.
* Oracle can interrupt Primal Beast's Onslaught charge with a well-timed Fortune's End.
* Primal Beast's lethal burst damage combos can be further stalled with False Promise; combined with Fate's Edict and regen from Purifying Flames, Oracle can even completely negate Primal Beast's offense.
Additional:
* Fate's Edict completely negates all of Primal Beast's major damage-dealing spells in the early game and can render Primal Beast useless when cast on a target he is focusing, or in Oracle's defense against Primal Beast himself.
* Fortune's End keeps Primal Beast in place, especially while trampling or in the middle of an Onslaught charge.
* False Promise can interrupt Primal Beast's Pulverize, as well as further delay Primal Beast from dealing lethal burst damage. In combination with Fortune's End, Oracle can potentially save an ally from Primal Beast's spell combos.

* Shukuchi allows Weaver to have faster move-speed and can outrun Primal Beast in most instances, such as while he is trampling.
* Trample disarms Primal Beast, so casting The Swarm can make him vulnerable to ranged attacks. Primal Beast also has an innately slow attack speed and will take long destroying the latched parasite.
* Time Lapse allows Weaver to negate and heal burst damage, which Primal Beast is reliant on.

* Phantom Lancer with Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.

* The ensare from melee Berserker's Rage can prevent Primal Beast from dealing further Trample damage and can allow Troll Warlord to relentlessly build Fervor on him.
* Whirling Axes (Ranged) can slow down Primal Beast while trampling and allow Troll Warlord to better control him from range.
* Whirling Axes (Melee) can blind Primal Beast if he attempts to auto-attack Troll Warlord after a fully charged Uproar.
* Battle Trance will make Primal Beast a sitting duck should he be rooted and attacked to death. It might be wise to save Pulverize for after this spell is used so you have a defensive measure against Troll Warlord.

* Power Cogs keeps Primal Beast pinned down, preventing him from doing damage with Trample. Primal Beast's slow attack speed makes it hard for him to break the cogs and get away. In addition, Power Cogs' knockback is forced movement, and thus will intercept Primal Beast's Onslaught if placed well.
* Battery Assault on a lone Primal Beast in the early game effectively keeps him from winding up Onslaught or basic attacking.
* Rocket Flare and Jetpack (from purchasing Aghanim's Shard) give Clockwerk many options to scout for Primal Beast, whose kit benefits greatly from ambushing.

* Diabolic Edict makes Leshrac very effective at threatening early towers and objectives which can directly cause unfavourable conflicts with Primal Beast early before he has Black King Bar to deal with the magical damage.
* Pulse Nova and the rest of Leshrac's spells can overwhelm Primal Beast with magical damage.
* Leshrac has generally faster movement speed than Primal Beast, especially if he has items such as Boots of Travel and Eul's Scepter of Divinity.
* Bloodstone also makes him heal much more than Primal Beast can damage him at any stage of the game.

* Rolling Boulder and Geomagnetic Grip allows Earth Spirit to easily stun, silence and interrupt Primal Beast in fights. Rolling Boulder can also be used to escape Primal Beast.
* Boulder Smash can push Primal Beast away and disrupt his Trample. In combination with Stone Remnant, Primal Beast can be slowed from a distance.

* Glimpse can prevent Onslaught in the laning stage very easily.
* While Static Storm is not much of a threat in terms of damage, it does prevent Primal Beast from casting any spells for a long period of time if also trapped in Kinetic Field.
* Overall, Disruptor forces Primal Beast to buy a Black King Bar much earlier than he might like but becomes a major threat to Disruptor once he does.

* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.

* Time Walk makes it impossible for Primal Beast to stay on top of Faceless Void with his abilities and allows him to heal burst damage dealt to him.
* Once Faceless Void has an Aghanim's Shard, Onslaught can be easily escaped. He could also choose to get a lower cooldown on Time Walk, making it even harder for Primal Beast to catch him in fights or stop his initiations.
* Time Dilation will make Primal Beast useless for an extended time after casting his abilities if he does not have a dispel.
* Chronosphere has many uses such as stopping Primal Beast from casting abilities on him or allies or even on a teammate, since Primal Beast has no way to assist allies trapped within the sphere.

* Phantom's Embrace is very threatening due to Primal Beast being quite spell reliant, and not being able to attack during Trample and can immediately cancel Pulverize.
* Soulbind can prevent movement in a way that's very hampering for Primal Beast's Trample and Onslaught. It can also cancel Onslaught very abruptly.
* Ink Swell can stun Primal Beast and give the holder a strong dispel with the shard. The stun can easily stop Trample damage or Pulverize from continuing even if it's not Primal Beast's main target.

* Primal Beast is mostly played in the offlane role, so picking a carry who can escape from him is essential. Heroes such as Troll Warlord, Lone Druid and Outworld Destroyer, or generally any carry with a stun, slow or ability to fight back will stop him from having the good start he needs.

* Primal Beast really suffers against supports he cannot bully in the lane; this includes Dazzle, Shadow Demon and Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.

* Primal Beast really suffers against supports he cannot bully in the lane; this includes Dazzle, Shadow Demon and Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.

* Primal Beast is mostly played in the offlane role, so picking a carry who can escape from him is essential. Heroes such as Troll Warlord, Lone Druid and Outworld Destroyer, or generally any carry with a stun, slow or ability to fight back will stop him from having the good start he needs.

* Supports who can slow him to the point Trample does very little damage in lane are also not fun: Lich, Ogre Magi, Winter Wyvern.

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Supports who can slow him to the point Trample does very little damage in lane are also not fun: Lich, Ogre Magi, Winter Wyvern.

* Supports who can slow him to the point Trample does very little damage in lane are also not fun: Lich, Ogre Magi, Winter Wyvern.

* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and Anti-Mage.

* Primal Beast really suffers against supports he cannot bully in the lane; this includes Dazzle, Shadow Demon and Dark Willow since they can use their respective abilities to stop Primal Beast from dealing burst damage, or make it hard for him to stay in range.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. He can force her to use Manta Style before he has cast Global Silence and Medusa usually does not want to build Black King Bar.

* Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* Arena Of Blood blocks Medusa's attacks from outside the arena.