Medusa
* 
Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's 
Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with 
Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive 
Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious 
Stone Gaze.
* Mana Burn quickly destroys 
Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from 
Mystic Snake and Split Shot can trigger Spiked Carapace.
* 
Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Skywrath Mage
* Slow-moving projectiles: 
Skywrath Mage, 
Tinker, 
Necrophos
Additional:
* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* 
Mind Flare turns Skywrath Mage's high intelligence growth against him and deals heavy damage.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.
Medusa
* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* 
Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. He can force her to use 
Manta Style before he has cast 
Global Silence and Medusa usually does not want to build 
Black King Bar.
Skywrath Mage
* Heroes with silence such as 
Riki, 
Silencer, or 
Night Stalker prevents Skywrath Mage from using his spells.
Medusa
* Medusa lacks mobility or escape mechanisms. 
Earth Spike and 
Hex can neutralize her strong damage potential and allow for 
Lion's team to focus her down.
* 
Mana Drain is a perfect ability to weaken Medusa's durability as it can quickly drain her Mana Shield, making her far less tanky. Mana Drain can also be used to restore mana of Lion's allies, which can nullify the mana steal from Mystic Snake.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.
Skywrath Mage
* Skywrath's pitiful defences also make him easy meat to heroes with high burst like 
Juggernaut, Lion, or 
Phantom Assassin, the latter occasionally downing a support Skywrath in a single 
Stifling Dagger.
Medusa
* Phantom Lancer with 
Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* 
Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.
Skywrath Mage
* Skywrath Mage also has a terrible time fighting against anything that isn't a hero. His skills are mostly target-based and he has terrible strength and agility, he can easily be kited or harassed by illusion-based heroes like 
Chaos Knight and 
Phantom Lancer, or by Heroes that summon other units like 
Lone Druid, 
Lycan and 
Beastmaster.
Medusa
* Anti-Mage easily destroys Mana Shield with Mana Break, especially once he has Manta Style.
* Anti-Mage effectively avoids Stone Gaze with Blink, and can reinitiate after its duration is over.
Additional:
* 
Mana Break burns Medusa's mana easily, especially when coupled with a Manta Style.
* Can easily initiate on Medusa with 
Blink, burning her mana or forcing her to use Stone Gaze.
* 
Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.
Skywrath Mage
* Mana Break drains Skywrath Mage of his mana, slowing him and dealing bonus damage while rendering him unable to cast his spells.
* Blink makes it incredibly easy for Anti-Mage to close the gap between himself Skywrath Mage to right-click him down. He can also use Blink to get away and escape into fog of war.
* Anti-Mage passively reduces enemy spell damage with 
Counterspell, and can activate the ability to block and send back Skywrath's Ancient Seal or Arcane Bolt, causing him to silence himself or deal massive damage to himself.
* Skywrath Mage's large mana-costs makes him an easy target for Mana Void.
* Anti-Mage often builds Black King Bar and Manta Style which can dispel Ancient Seal and Concussive Shot.
Skywrath Mage
* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Lion, Silencer, 
Shadow Shaman, 
Grimstroke, 
Witch Doctor, Riki, 
Faceless Void, Skywrath Mage, 
Puck.
Medusa
* 
Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* 
Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.
Skywrath Mage
* Skywrath Mage's armor and agility gain is very low, so when Huskar's Burning Spears stack they can take him down very quickly at any point of the game.
* 
Berserker's Blood grants bonuses as Huskar uses Burning Spears to harass Skywrath Mage, granting him attack speed, magic resistance, and strength as health regen, making it possible that Huskar can harass Skywrath Mage out of lane and sustain through his magic burst through staying injured throughout lane, or even the game.
* 
Life Break allows Huskar to jump onto Skywrath Mage, closing the distance between them and busting him down so he cannot run. This can be combed with Inner Fire, adding a movement speed slow if Aghanim's Shard is applied so Skywrath Mage cannot escape.
Skywrath Mage
* Heroes with high magical burst can easily kill Huskar when he is at low health: Lion, 
Lina, Skywrath Mage
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, 
Naga Siren, 
Terrorblade, Juggernaut, 
Spectre, 
Slark.
Skywrath Mage
* Skywrath's pitiful defences also make him easy meat to heroes with high burst like Juggernaut, Lion, or Phantom Assassin, the latter occasionally downing a support Skywrath in a single Stifling Dagger.
Skywrath Mage
* Fate Edict can completely negate Skywrath Mage's heavy magic damage.
* Fortune End dispels 
Ancient Seal.
Medusa
* He can use either his own or his double's 
Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + 
Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double 
Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.
Medusa
* Ursa's status resistance from 
Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with 
Fury Swipes easily against her Mana Shield in a prolonged team match.
Additional:
* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Skywrath Mage
* In the early-mid game, Skywrath consistently needs to use his entire mana pool to kill a hero, but Wraith King's 
Reincarnation allows him to finish off Skywrath after the first death, as Skywrath Mage will have likely expended all his mana.
Medusa
* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, 
Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away all of Medusa's mana.
Additional:
* 
Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.
Skywrath Mage
* Outworld Destroyer can steal more mana with 
Astral Imprisonment from Skywrath Mage with 
Shield of the Scion (granted by 
Aghanim's Shard). Shield of the Scion grants Skywrath Mage bonus intelligence every time he deals magic damage to an enemy hero with his abilities. The higher his intelligence, the larger his mana pool. Since Astral Imprisonment steals based on the target's max mana, Outworld Destroyer can steal much more mana from Skywrath Mage.
Medusa
* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* 
Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.
Medusa
* With 
Static Link, Razor can effectively make Medusa useless in teamfights by reducing her main damage output. It can, however, be blocked by a 
Linken's Sphere.
* 
Plasma Field allows Razor to get on top of Medusa, slowing her already slow movement speed to a mere crawl.
* 
Eye of the Storm capitilizes on Medusa's low armor and causes her to be very vulnerable, even through Mana Shield.
Medusa
* Medusa is especially vulnerable to 
Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* 
Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.
Additional:
* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift particularly removes 1 intelligence point per hit, thus lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Skywrath Mage
* Due to the high mana cost of his spells and the low cool down of them, Nether Ward can seriously damage Skywrath Mage if he isn't careful.
* Skywrath Mage's fragility makes him very susceptible to Pugna's high burst damage.
Additional:
* 
Nether Ward will make Skywrath Mage next to useless in fights, as his low hp pool will not allow him to sustain through the damage of the ward should he choose to cast spells. Be wary though that Skywrath's huge burst will make very quick work of Pugna's low hp should the ward be destroyed, and 
Decrepify won't help Pugna at all.
Medusa
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.
Additional:
* Medusa is a fairly immobile hero that deals damage around her with Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Medusa
* E.M.P. allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* 
E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* 
Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* 
Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.
Skywrath Mage
* Templar Assassin easily withstands all the damage from Skyrwrath Mage, thanks to its first ability 
Refraction. In addition, Templar Assassin can kill Skywrath Mage with a single hit from under the second ability 
Meld.
Additional:
* Templar Assassin easily withstands all the damage from Skyrwrath Mage, thanks to its first ability Refraction. In addition, Templar Assassin can kill Skywrath Mage with a single hit from under the second ability Meld.
Skywrath Mage
* Skywrath Mage's very low health allows Monkey King to ambush and finish him off quickly.
Skywrath Mage
* In general, heroes that deal burst in multiple instances will trigger Borrowed Time and heal Abaddon for a large amount, such as Skywrath Mage, 
Techies, Juggernaut, Shadow Shaman, or 
Ogre Magi.
Additional:
* 
Aphotic Shield removes silences, slows and stuns, possibly foiling a full-duration Mystic Flare.
* 
Borrowed Time makes it impossible to burst 
Abaddon down, even healing him up due to Mystic Flare's damage.
Skywrath Mage
* Heroes with silence such as Riki, Silencer, or Night Stalker prevents Skywrath Mage from using his spells.
Skywrath Mage
* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:
Crystal Maiden, 
Pugna, Skywrath Mage, 
Io, Witch Doctor, etc.
Medusa
* Heroes who take a long time to become strong are in for a rough mid game, such as 
Outworld Destroyer, 
Magnus, Medusa, and 
Anti-Mage.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: 
Tidehunter, 
Bristleback, 
Slardar.
Medusa
* Hard carries who just want to farm and be left alone will not appreciate Primal Beast, heroes such as Medusa, 
Drow Ranger...
Skywrath Mage
* Heroes with a low health pool (Crystal Maiden, Skywrath Mage etc)
Medusa
* Heroes with extremely slow movement speed will cripple against Solar Bind: Medusa, 
Viper
Additional:
* 
Will-O-Wisp will keep Medusa busy after she got hit by 
Blinding Light.
Skywrath Mage
* Skywrath Mage also has a terrible time fighting against anything that isn't a hero. His skills are mostly target-based and he has terrible strength and agility, he can easily be kited or harassed by illusion-based heroes like Chaos Knight and Phantom Lancer, or by Heroes that summon other units like Lone Druid, Lycan and Beastmaster.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.
Skywrath Mage
* 
Mystic Flare can easily burst down Legion Commander while she is Dueling.
Medusa
* Medusa's Split Shot can easily kill Chen's creeps.
* Mystic Snake can quickly kill Chen's creeps and deal intense damage for every killed creep while also draining their mana with each bounce. Aghanim's Scepter upgraded Mystic Snake can also disable both, Chen and his creeps upon impact.
* Mana Shield will make it impossible for Chen to burst down Medusa.
* Stone Gaze can disable Chen from using 
Hand of God to save himself or his allies.
Skywrath Mage
* Heroes with either magical, physical or pure damage burst: 
Bane, 
Ember Spirit, 
Leshrac, Lina, 
Luna, 
Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, 
Ursa, 
Void Spirit.
Medusa
* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.
Skywrath Mage
* Heroes with nukes: Bane, 
Lich, Lion, Skywrath Mage
Additional:
* 
Untouchable is useless versus constant Arcane Bolts, and it doesn't help that her strength gain is the lowest in the game.
* A jungle Enchantress can weaken lanes and make Skywrath Mage's job easier.
* The magic amplification from Ancient Seal makes her even squishier to Skywrath and his allies' magic nukes.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, 
Zeus.
Skywrath Mage
* Heroes with long range abilities are also able to touch Zeus, such as 
Clockwerk, 
Kunkka, Puck, Skywrath Mage, 
Spirit Breaker, 
Tusk and others.
Medusa
* Heroes that are hard to gank: 
Axe, 
Death Prophet, Phantom Lancer, Slark, 
Centaur Warrunner, Bristleback, Medusa, 
Mars.
Skywrath Mage
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Skywrath Mage
* 
Arcane Bolt's low cooldown allows him to deal consistent damage to Morphling, and is a viable way to disable Linken's Sphere.
* Ancient Seal prevents Morphling from using any of his skills, giving Skywrath Mage and his team ample time to burst Morphling down.
* Mystic Flare coupled with a stun/root can easily burst Morphling down, especially if he has more stats shifted to Agility.
* Alternatively, Morphling can use Morph to use Skywrath Mage's own silence and nukes against him.
Medusa
* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.
Medusa
* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.
Skywrath Mage
* Similar to 
Timbersaw, Storm Spirit builds items that don't help against silences.
* An 
Orchid Malevolence will most likely silence you first. However, if you grab a 
Eul's Scepter of Divinity, you might dispel his silence and turn the tides to your favor.
* Root and silence are 
Storm Spirit's ultimate counters. Skywrath Mage has a silence in his kit, and has 
Rod of Atos as his core item. If he dispels one, you cast the other, both leaving him vulnerable.
* If he builds Black King Bar, he spends 4050 gold that doesn't help him snowball effectively.
Medusa
* Mana Shield can tank most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.
Medusa
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and 
Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with 
Lucent Beam.
* Medusa can survive 
Eclipse thanks to Mana Shield, which can cause Luna to struggle greatly in bursting down Medusa and force her to buy Diffusal Blade and it's upgrade 
Disperser.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Skywrath Mage
* Magical burst damage is Timbersaw's weakness, and Ancient Seal not only amplifies it but also prevents him from using 
Timber Chain to escape for up to 6 seconds.
* He generally doesn't build early items to deal with silences.
* 
Reactive Armor does not trigger on magic damage or spells, meaning that even a 
Pipe of Insight won't give him the massive sustain he normally gets from attacks.
Additional:
* Skywrath Mage's long range and low cooldown magic damage spells can easily harass Timbersaw out of lane.
* Ancient Seal is not only a long lasting silence, (one of Timbersaw's biggest weaknesses) but it also makes him even more vulnerable to magical burst damage.
Skywrath Mage
* A good Skywrath Mage with quick fingers will punish Queen of Pain for blinking aggressively. Ancient Seal is a six second silence with no cast time, so he can interrupt either her Shadow Strike or Sonic Wave, and a good Mystic Flare on top of that will seal the deal for her.
* Ancient Seal also has pretty good range so he could get it off before she blinks away.
Skywrath Mage
* Ancient Seal can silence Jakiro and make him vulnerable to magical spells up to 6 seconds.
* Skywrath Mage can usually burst down Jakiro with his high damage magical spells.
Medusa
* If Medusa activates Stone Gaze before Spirit Breaker reaches her with Charge of Darkness, the charge will inevitably fail.
* Medusa has three ways to counter Spirit Breaker's Charge of Darkness: Stone Gaze can disable Spirit Breaker's Charge of Darkness if he faces Medusa directly. Aghanim's Scepter upgraded Mystic Snake can disable Spirit Breaker and cancel his Charge of Darkness if it hits him. And 
Cold Blooded provided by Aghanim's Shard that can cast a single-targeted Mystic Snake at Spirit Breaker if he uses Charge of Darkness on her.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation. And to make things worse, Spirit Breaker is not a common Diffusal Blade nor Disperser wielder to counter this problem at all.
* Overall, any attempt for Spirit Breaker to gank and kill Medusa will hurt him more than the other way around.
Skywrath Mage
* Ancient Seal's instant cast time will often silence Brewmaster before he can do anything.
* Brewmaster also has no defense against Skywrath Mage's massive magical damage.
Skywrath Mage
* Ancient Seal instantly shuts down Dark Willow's abilities, rendering her defenseless against his high burst damage spells, while she cannot cast spells of her own.
* Mystic Flare deals immense burst damage in an area, damaging Dark Willow through Shadow Realm.
Skywrath Mage
* Skywrath's pitiful defences also make him easy meat to heroes with high burst like Juggernaut, Lion, or Phantom Assassin, the latter occasionally downing a support Skywrath in a single Stifling Dagger.
Medusa
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, 
Enigma, 
Vengeful Spirit, 
Doom, Bane, Beastmaster, 
Pudge, Medusa, 
Warlock.
Skywrath Mage
* While Phantom Assassin can kill Skywrath Mage in a few strikes, Skywrath Mage can also do the same to her if she is not careful.
* Arcane Bolt's long range and low cooldowns allows Skywrath Mage to severely harass Phantom Assassin in lane.
* Ancient Seal prevents Phantom Assassin from escaping or engaging with 
Phantom Strike.
* Mystic Flare's heavy magical damage nukes Phantom Assassin down quickly during the early to mid game.
Additional:
* While Phantom Assassin can kill Skywrath Mage in a few strikes, Skywrath Mage can also do the same to her if she is not careful.
* Arcane Bolt's long range and low cooldowns allows Skywrath Mage to severely harass Phantom Assassin in lane.
* Ancient Seal prevents Phantom Assassin from escaping or engaging with Phantom Strike.
* Mystic Flare's heavy magical damage nukes Phantom Assassin down quickly during the early to mid game.
Skywrath Mage
* Skywrath Mage can easily harass Alchemist in the laning phase with multiple Arcane Bolts. Additionally, if Alchemist is in the process of throwing an 
Unstable Concoction, and has no way to dispel Ancient Seal, the self stun becomes an easy set up for Mystic Flare.
* Caution, however, as a decently farmed Alchemist with {Item ID:Radiance} and {Item ID:Manta Style} can easily send illusions to harass and force Skywrath Mage out.
Skywrath Mage
* Arcane Bolt allows Skywrath Mage to harass Earthshaker out of lane.
* Ancient Seal is an instant silence that can be pre-cast onto Earthshaker to disrupt his combo, before he uses 
Blink Dagger to initiate.
* Mystic Flare will nuke Earthshaker down while he stands in place during his long cast animations.
Medusa
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating and landing an effective 
Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult. Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.
Medusa
* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.
Medusa
* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.
Medusa
* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces 
Rage, wasting its cooldown and making Lifestealer unable to fight.
Medusa
* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to fight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalize on his commitment in a fight.
Skywrath Mage
* Skywrath Mage should have the upper hand against Vengeful Spirit with Ancient Seal.
* Vengeful is highly dependant on her abilities and has no natural means to deal against silences.
* Her low attack range allows Skywrath Mage to easily bully her out of the lane.
Skywrath Mage
* 
Cold Embrace is a perfect setup for Mystic Flare.
* Winter Wyvern is a spellcaster, and the 6 second silence from Ancient Seal can prevent her from contributing much.
* Because Skywrath Mage tends to stay back in fights, Winter Wyvern will have to get close to a teamfight to cast 
Winter's Curse on him. And if she chooses to cast it on one of his allies, his low attack speed and damage means that he won't do much.
* However, bear in mind that Skywrath Mage has seriously awful armor, and that can make him an adequate target to being turned against his own team with Winter's Curse, which can result in his death quickly.
Additional:
* Cold Embrace is the perfect setup for Mystic Flare, and his 6-second silence is good against Winter Wyvern in general.
Medusa
* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.
Skywrath Mage
* Skywrath Mage stands perfectly on the center line against Tinker, thanks to his nuke and silence. Also, thanks to his abilities, he can quickly kill a victim, and Tinker is one of the most subtle heroes in the game
Additional:
* Skywrath Mage stands perfectly on the center line against Tinker, thanks to his nuke and silence. Also, thanks to his abilities, he can quickly kill a victim, and Tinker is one of the most subtle heroes in the game
Medusa
* Any long duration disables that can pierce through both, Pierce The Veil and Black King Bar are devastating against Muerta: Enigma's Black Hole, 
Dawnbreaker's 
Solar Guardian, Axe's 
Berserker's Call, Naga Siren's Aghanim's Scepter upgraded 
Ensnare and 
Reel In from Aghanim's Scepter, 
Jakiro's Aghanim's Scepter upgraded 
Macropyre, Bane's Fiend's Grip, Pudge's 
Dismember, 
Batrider's 
Flaming Lasso, Beastmaster's 
Primal Roar, Grimstroke's 
Soulbind, Medusa's Stone Gaze, Magnus's 
Reverse Polarity.
Skywrath Mage
* Heroes with powerful spammable abilities will prove problematic for Grimstroke as Ink Swell does not protect him from them: Zeus, Skywrath Mage, Tinker, Lina
Medusa
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: 
Sven, 
Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, 
Venomancer, 
Elder Titan, Faceless Void, 
Rubick, 
Keeper of the Light, Pugna, 
Invoker, Spectre, 
Alchemist, 
Treant Protector, Lina, 
Oracle, Zeus, Shadow Shaman, 
Phoenix, 
Razor, 
Huskar, Batrider, Kunkka, Tidehunter, 
Wraith King, 
Sand King, Medusa, Dawnbreaker.
Skywrath Mage
* Heroes that can easily kill Faceless Void from outside his Cronosphere; 
Sniper, Skywrath Mage, etc.
Skywrath Mage
* Silence (and mana burns) will be a persistent problem for Phoenix, as it is heavily reliant on its abilities whether defensively or offensively, so heroes like Death Prophet, Skywrath Mage, and even Nyx Assassin must be closely observed to prevent being shut down by these heroes.
* Hexes are a greater threat to Phoenix as they also disable items, preventing Phoenix from dispelling the debuff on its own.
Skywrath Mage
* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.
Skywrath Mage
* Even though Linken's Sphere will block your silence, you can cast Arcane Bolt to break it or wait until someone on your team breaks it. In addition, Linken's Sphere builders are usually squishy targets vulnerable to silences: 
Weaver, 
Queen of Pain, 
Morphling, 
Clinkz, etc. Don't forget that Ancient Seal also increases the magical damage these enemies take, along with silencing them.
Additional:
* Arcane Bolt has a long range and a low cooldown, and is a great spell to waste Linken's Sphere. It also serves as an effective spell to harass Weaver with.
* Ancient Seal prevents Weaver from using Shukuchi or Time Lapse.
Skywrath Mage
* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, Tinker, Leshrac, Viper, Skywrath Mage, Lion, Lina, Venomancer.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Skywrath Mage
* Skywrath Mage's Mystic Flare can deal huge damage to Clockwerk inside his Power Cogs.
Skywrath Mage
* Even though Linken's Sphere will block your silence, you can cast Arcane Bolt to break it or wait until someone on your team breaks it. In addition, Linken's Sphere builders are usually squishy targets vulnerable to silences: Weaver, Queen of Pain, Morphling, Clinkz, etc. Don't forget that Ancient Seal also increases the magical damage these enemies take, along with silencing them.
Skywrath Mage
* Lich is heavily reliant on his abilities to contribute to team fights, so be wary of enemies that can Silence: 
Bloodseeker, Death Prophet, Silencer, Drow Ranger, Skywrath Mage.
Medusa
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's 
Arena of Blood, Jakiro's Macropyre, 
Dual Breath and 
Ice Path, Naga Siren's 
Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's 
Light Strike Array, 
Broodmother's 
Spinner's Snare from Aghanim's Scepter, Elder Titan's 
Earth Splitter and 
Echo Stomp, Alchemist's Unstable Concoction and 
Acid Spray, Queen of Pain's 
Sonic Wave, 
Dark Seer's 
Wall of Replica and 
Vacuum, Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from Aghanim's Shard, Bloodseeker's 
Blood Rite, Enigma's Black Hole and 
Midnight Pulse, 
Shadow Fiend's 
Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, 
Ancient Apparition's 
Ice Blast, Sand King's 
Epicenter, 
Sand Storm and 
Burrowstrike, 
Gyrocopter's 
Call Down, Ember Spirit's 
Sleight of Fist, Death Prophet's 
Exorcism and 
Silence, 
Monkey King's 
Wukong's Command, Crystal Maiden's 
Freezing Field, 
Muerta's 
The Calling, Medusa's Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, 
Pangolier's 
Swashbuckle, Grimstroke's Soulbind, 
Ink Swell and 
Stroke of Fate, 
Earthshaker's 
Echo Slam and 
Fissure, Puck's 
Dream Coil and 
Waning Rift, 
Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Skywrath Mage
* Arcane Bolt can target Terrorblade's low health pool in the laning phase.
* Ancient Seal can prevent Terrorblade from casting Sunder.
* Mystic Flare can be used to great effect to burst Terrorblade down before he gets a Manta Style or a Black King Bar.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Medusa
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Additional:
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Skywrath Mage
* Once you get a Black King Bar, squishy spellcasters like Zeus, Skywrath Mage and others will be probably easy to deal with.
Medusa
* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake
Skywrath Mage
* Skywrath Mage's abilities are single targeted and he can't use Mystic Flare to its fullest potential, since all Meepos spread the damage between them. He also has no disables to prevent Meepo from Poofing to another one (unless he can get Ancient Seal off first).
Medusa
* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.
Skywrath Mage
* Skywrath Mage also has a terrible time fighting against anything that isn't a hero. His skills are mostly target-based and he has terrible strength and agility, he can easily be kited or harassed by illusion-based heroes like Chaos Knight and Phantom Lancer, or by Heroes that summon other units like Lone Druid, Lycan and Beastmaster.
Skywrath Mage
* Mystic Flare can be used to effectively ignore the Spirit Bear entirely and burst Lone Druid during the early mid game.
* 
Concussive Shot and Arcane Bolt will provide vision of Lone Druid allowing for better chase in teamfights before the Spirit Bear can do too much damage.
* Ancient Seal denies the ability to transform into 
True Form and receive bonus HP from the skill.
Medusa
* 
Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* 
Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* Arena Of Blood blocks Medusa's attacks from outside the arena.
Medusa
* Medusa's Stone Gaze forces Mars to choose between getting petrified, or turning his vulnerable back on Medusa.
Skywrath Mage
* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.
Skywrath Mage
* Skywrath Mage also has a terrible time fighting against anything that isn't a hero. His skills are mostly target-based and he has terrible strength and agility, he can easily be kited or harassed by illusion-based heroes like Chaos Knight and Phantom Lancer, or by Heroes that summon other units like Lone Druid, Lycan and Beastmaster.
Medusa
* Heroes with Linken's Sphere as core item: Weaver, Morphling, Medusa.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.
Medusa
* Axe can take advantage of Medusa's awfully low HP to insta-kill her with 
Culling Blade, making it extremely difficult for her to farm for items to compensate for the lack of strength during early and mid-game while Axe is continuously harassing around.
Medusa
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.
Medusa
* With
Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
Cloak and Dagger, even through Mana Shield.
* He can deal a huge amount of damage through
Skywrath Mage
* Due to his low health and armor, Riki can easily kill Skywrath Mage.
Black King Bar.
* Smoke Screen prevents Skywrath from using all of his abilities, as he does not tend to buy
* However, Skywrath Mage can easily kill Riki if he manages to root Riki with Rod of Atos or Gleipnir, followed by Dust of Appearance, Ancient Seal and Mystic Flare.