Medusa
* Ursa's status resistance from 
Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with 
Fury Swipes easily against her Mana Shield in a prolonged team match.
Additional:
* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Winter Wyvern
* Even though Ursa is a hero who relies on direct attacks to be effective, Fury Swipes does not work on allies if Ursa is affected by Winter's Curse, mitigating a majority of Ursa's damage. In addition, Ursa's unimpressive attack speed and attack damage without 
Overpower and Fury Swipes means that he deals little to no damage to allies during Winter's Curse.
* 
Aghanim's Scepter upgraded Enrage allows Ursa to survive Winter Wyvern's initiation with Winter's Curse.
Medusa
* Medusa is especially vulnerable to 
Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* 
Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.
Additional:
* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift particularly removes 1 intelligence point per hit, thus lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Winter Wyvern
* Arctic Burn and Splinter Blast debuffs are dispellable with Dark Pact. Arctic Burn is also no escape against 
Pounce.
* Cold Embrace gives Slark free Essence Shift stacks.
* However, Essence Shift works against allies, and Slark's low health pool means that if he's the target for Winter's Curse, he will go down very quickly.
Medusa
* Fiend's Grip provides mana drain, which can heavily damage 
Mana Shield and prevent Medusa from using 
Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* 
Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.
Winter Wyvern
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: 
Disruptor, 
Death Prophet, 
Enigma, 
Faceless Void, 
Invoker, 
Lich, 
Magnus, 
Mars, 
Medusa, 
Outworld Destroyer, 
Phoenix, 
Puck, 
Queen of Pain, 
Shadow Fiend, 
Treant Protector, 
Underlord, 
Winter Wyvern, 
Witch Doctor, 
Zeus.
Medusa
* He can use either his own or his double's 
Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + 
Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double 
Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.
Medusa
* 
Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* 
Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.
Medusa
* Anti-Mage easily destroys Mana Shield with Mana Break, especially once he has 
Manta Style.
* Anti-Mage effectively avoids Stone Gaze with Blink, and can reinitiate after its duration is over.
Additional:
* 
Mana Break burns Medusa's mana easily, especially when coupled with a Manta Style.
* Can easily initiate on Medusa with 
Blink, burning her mana or forcing her to use Stone Gaze.
* 
Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.
Winter Wyvern
* All of his damage is magical and pure, which makes Cold Embrace a good setup for his nukes.
* Winter's Curse is very hard to cast on Tinker because he usually stays in the back-lines in team-fights. In turn, Tinker has mediocre attack damage and will contribute very little when he is cursed to attack an ally. He can also save his ally under Winter's Curse effect with 
Ethereal Blade and 
Defense Matrix.
Medusa
* With 
Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
* He can deal a huge amount of damage through 
Cloak and Dagger, even through Mana Shield.
Medusa
* 
Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's 
Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive 
Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from 
Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Winter Wyvern
* Outworld Destroyer's pure damage from Arcane Orb can go through 
Cold Embrace.
* Outworld Destroyer can negate the healing from Cold Embrace using Astral Imprisonment, and steal mana while doing so.
* Outworld Destroyer's damage during 
Winter's Curse is reduced due to Arcane Orb being unable to target allies.
Additional:
* Winter Wyvern must never put her allies in Cold Embrace against Outworld Destroyer as 
Arcane Orb will continue to deal damage to the defenseless hero.
* Arcane Orb does not hit his allies when he is taunted by Winter's Curse, making it weak against allies, but strong versus enemies.
* 
Astral Imprisonment can protect a target inflicted with Winter's Curse.
Winter Wyvern
* Cold Embrace makes its target immovable, allowing Ancient Apparition to easily land Ice Blast, or a Cold Feet stun.
* Ice Blast also negates healing from Cold Embrace.
Additional:
* 
Ice Blast disables the healing component of Cold Embrace, making it essentially a 4 second stun on an ally and a perfect setup for Ice Blast.
* If 
Cold Feet is cast on an Allied hero affected by Cold Embrace, it will almost guarantee the Ally comes out stunned.
Winter Wyvern
* Cold Embrace is a death sentence against Pugna, since its the perfect setup for all his abilities, especially 
Life Drain.
* 
Decrepify can be cast to save the ally under Winter's Curse effect, wasting most of its duration.
* Winter Wyvern's abilities require a lot of mana, allowing 
Nether Ward to deal lots of damage.
Medusa
* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* 
Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. He can force her to use Manta Style before he has cast 
Global Silence and Medusa usually does not want to build 
Black King Bar.
Winter Wyvern
* Guardian Angel completely counters Winter's Curse if Omniknight is able to cast it.
Additional:
* 
Guardian Angel completely counters Winter's Curse, allowing his team to survive Winter Wyvern's initiation.
* 
Purification and 
Heavenly Grace are very useful against Arctic Burn, Splinter Blast and Winter's Curse as well.
Winter Wyvern
* Cold Embrace is a perfect setup for Mystic Flare.
* Winter Wyvern is a spellcaster, and the 6 second silence from Ancient Seal can prevent her from contributing much.
* Because Skywrath Mage tends to stay back in fights, Winter Wyvern will have to get close to a teamfight to cast Winter's Curse on him. And if she chooses to cast it on one of his allies, his low attack speed and damage means that he won't do much.
* However, bear in mind that Skywrath Mage has seriously awful armor, and that can make him an adequate target to being turned against his own team with Winter's Curse, which can result in his death quickly.
Additional:
* Cold Embrace is the perfect setup for 
Mystic Flare, and his 6-second silence is good against Winter Wyvern in general.
Medusa
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.
Additional:
* Medusa is a fairly immobile hero that deals damage around her with Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Medusa
* Medusa lacks mobility or escape mechanisms. 
Earth Spike and 
Hex can neutralize her strong damage potential and allow for 
Lion's team to focus her down.
* In addition to easily breaking her commonly bought 
Linken's Sphere with its low cooldown, 
Mana Drain can quickly drain her Mana Shield, making her far less tanky.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.
Medusa
* With 
Static Link, Razor can effectively make Medusa useless in teamfights by reducing her main damage output. It can, however, be blocked by a Linken's Sphere.
* 
Plasma Field allows Razor to get on top of Medusa, slowing her already slow movement speed to a mere crawl.
* 
Eye of the Storm capitilizes on Medusa's low armor and causes her to be very vulnerable, even through Mana Shield.
Winter Wyvern
* Timbersaw relies on dealing massive amounts of pure damage, making Cold Embrace a good setup for his nukes.
* If he has 
Reactive Armor stacks, Timbersaw can tank the damage from his allies if he is targeted by Winter's Curse. If he's not the target, Timbersaw's abysmal attack damage will contribute next to nothing when he is cursed to attack an ally.
* Since Timbersaw build 
Lotus Orb, Winter's Curse is very useless for Winter Wyvern makes reflected back taunted to herself and ganking.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: 
Tidehunter, 
Bristleback, 
Slardar.
Medusa
* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and 
Anti-Mage.
Medusa
* Heroes with extremely slow movement speed will cripple against Solar Bind: Medusa, 
Viper
Additional:
* 
Will-O-Wisp will keep Medusa busy after she got hit by 
Blinding Light.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Phantom Lancer with 
Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* 
Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.
Winter Wyvern
* 
Broodmother, 
Nature's Prophet, 
Phantom Lancer by their nature offer very good target for Splinter Blast and Winter's Curse.
Medusa
* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, 
Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away all of Medusa's mana.
Additional:
* 
Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.
Winter Wyvern
* Broodmother, Nature's Prophet, Phantom Lancer by their nature offer very good target for Splinter Blast and Winter's Curse.
Medusa
* 
Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* 
Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* 
Arena Of Blood blocks Medusa's attacks from outside the arena.
Medusa
* Medusa's Stone Gaze forces Mars to choose between getting petrified, or turning his vulnerable back on Medusa.
Medusa
* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to fight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalize on his commitment in a fight.
Winter Wyvern
* Cold Embrace saves any ally Sven initiates on and wastes the duration of God's Strength in team fights.
* Winter's Curse can be devastating to Sven's team, as his massive damage can take out a teammate before there is much time to react.
Medusa
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating and landing an effective 
Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult. Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.
Winter Wyvern
* Winter's Curse, when directly targeted on Enigma, goes through Black King Bar, stopping Enigma's Black Hole channeling. It also turns his team against him, potentially killing him. Even if Enigma gets Linken's Sphere on top of Black King Bar, 
Splinter Blast can be used to pop Linken's Sphere, and Winter's Curse will stop Black Hole channeling.
* Splinter Blast can be targeted on an eidolon, killing off other eidolons and damaging nearby heroes as well.
Medusa
* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.
Winter Wyvern
* Cold Embrace saves allies from dying in Duels.
* Winter's Curse turns Legion Commander's high damage against her allies, giving the enemy team little time to react.
* However, Winter Wyvern lanes very poorly against Legion Commander due to Press the Attack removing all the debuffs she can give. Winter Wyvern also has little chances of surviving if she gets Dueled herself.
Additional:
* Cold Embrace is very effective against 
Duel.
* Also, casting Winter's Curse at 
Legion Commander while an ally is in a Duel will stun her for most of the duration, possibly preventing lethal damage dealt to your ally. It can also turn her high-damage against her teammate.
Medusa
* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake
Winter Wyvern
* 
Arctic Burn allows Winter Wyvern to escape Lycan, even when he uses his ultimate.
* Splinter Blast is very effective in dealing with Lycan's summons.
* Cold Embrace saves allies from Lycan's raw physical damage and can buy allies enough time to turn the tide of battle.
* Winter's Curse stops Lycan in his tracks and is very effective because of his summons.
Additional:
* All of Lycan's damage is physical which is totally negated by Cold Embrace.
* Lycan often moves around with large amount of creeps, wolves created by 
Summon Wolves and neutral creep dominated by 
Helm of the Dominator which can be easily cleared by Splinter Blast or used as a great source of damage by Winter's Curse. If you catch Lycan with creeps nearby and affected by 
Shapeshift using Winter's Curse on him will most certainly end up with his death.
Medusa
* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.
Winter Wyvern
* Winter's Curse in late game is pretty much the end for Meepo or any of his nearby allies. Natural counter for Winter's Curse like Linken's Sphere or Lotus Orb is meaningless to her if she can land it on one of your clones.
Additional:
* Meepo's clones usually gets grouped in teamfight making any of them ideal target for Winter's Curse, forcing Meepo to literally kill himself. Also, unlike other heroes he cannot protect himself with Linken's Sphere.
* While Meepo's clones are grouped up, Splinter Blast will hit almost every clone, slowing Meepo and making him easier to fight.
Medusa
* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.
Winter Wyvern
* Heroes with the ability to heal allies, or those with good defensive abilities: 
Chen, 
Dazzle, 
Io, 
Oracle, 
Omniknight, Witch Doctor, Winter Wyvern, 
Abaddon, etc.
Medusa
* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.
Winter Wyvern
* Heroes with other kind of disables that pierce spell immunity can hold Pangolier in place during Rolling Thunder: 
Axe, 
Beastmaster, Enigma, Magnus, 
Pudge, 
Batrider, 
Bane, Winter Wyvern
Medusa
* Heroes with Linken's Sphere as core item: 
Weaver, 
Morphling, Medusa.
Winter Wyvern
* Cold Embrace mitigates Primal Roar's single-target initiation on allies.
* Winter's Curse can turn Beastmaster's summons and Inner Beast against his teammate.
Additional:
* Beastmaster's summons and 
Inner Beast are very useful to attack his cursed teammate.
* Cold Embrace effectively mitigates 
Primal Roar's single-target initiation on allies.
Medusa
* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces 
Rage, wasting its cooldown and making Lifestealer unable to fight.
Winter Wyvern
* Many physical-only single-target heroes like 
Lifestealer, 
Sven, 
Wraith King, 
Phantom Assassin, 
Templar Assassin can have their damage mitigated by Cold Embrace.
Medusa
* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, 
Vengeful Spirit, 
Doom, Bane, Beastmaster, Pudge, Medusa, 
Warlock.
Winter Wyvern
* Many physical-only single-target heroes like Lifestealer, Sven, Wraith King, Phantom Assassin, Templar Assassin can have their damage mitigated by Cold Embrace.
Medusa
* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.
Winter Wyvern
* Winter's Curse and Splinter Blast can devastate Underlord's team when they're grouped up for Dark Rift.
Medusa
* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.
Medusa
* If Medusa activates Stone Gaze before Spirit Breaker reaches her with Charge of Darkness, the charge will inevitably fail.
* Medusa has three ways to counter Spirit Breaker's Charge of Darkness: Stone Gaze can disable Spirit Breaker's Charge of Darkness if he faces Medusa directly. Aghanim's Scepter upgraded Mystic Snake can disable Spirit Breaker and cancel his Charge of Darkness if it hits him. And 
Cold Blooded provided by 
Aghanim's Shard that can cast a single-targeted Mystic Snake at Spirit Breaker if he uses Charge of Darkness on her.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation. And to make things worse, Spirit Breaker is not a common Diffusal Blade nor 
Disperser wielder to counter this problem at all.
* Overall, any attempt for Spirit Breaker to gank and kill Medusa will hurt him more than the other way around.
Winter Wyvern
* Cold Embrace can protect Troll Warlord's target, especially during Battle Trance.
* Winter's Curse can turn Troll Warlord's high physical damage and attack speed against his allies.
Additional:
* Cold Embrace will protect your ally from being damaged if he gets focused by Troll, although be careful as 
Fervor will keep gaining stacks even while Cold Embrace is active.
* Fervor works on allies.
* His high attack speed will help to kill his cursed ally faster.
Medusa
* Mana Shield can tank most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.
Winter Wyvern
* Cold Embrace can heal herself or an ally, as well as protecting them from Clinkz's physical attacks and wasting his mana if Searing Arrows is on autocast.
* Winter's Curse allows Winter Wyvern to turn Clinkz's high damage and high attack speed against his allies, or take advantage of Clinkz's fragility if he can't use Skeleton Walk.
Winter Wyvern
* Cold Embrace can render the extra attack speed from Overcharge meaningless.
* Splinter Blast and Winter's Curse are very affective against Io, as it has to stay close to its tethered hero.
Winter Wyvern
* Cold Embrace protects Reality Rift targets.
* Winter's Curse turns Phantasm illusions against Chaos Knight or a teammate.
* Splinter Blast deals decent area damage to Phantasm illusions.
* Arctic Burn's percentage-based damage quickly wears down Chaos Knight's high max health.
Additional:
* Winter Wyvern can make Chaos Knight's illusions attack the real one, provided the player knows who it is.
* Alternatively, Winter's Curse can make Chaos Knight and all his illusions attack one of his allies.
* Cold Embrace protects ally who is focused by Chaos Knight.
* Splinter Blast deals decent area damage to Chaos Knight's illusions.
* Chaos Knight's high health pool and tendency to not build magic resistance items will make Arctic Burn deal a lot of damage to him and his illusions.
Medusa
* Medusa's Split Shot can easily kill Chen's creeps.
* Mystic Snake can quickly kill Chen's creeps and deal intense damage for every killed creep while also draining their mana with each bounce. Aghanim's Scepter upgraded Mystic Snake can also disable both, Chen and his creeps upon impact.
* Mana Shield will make it impossible for Chen to burst down Medusa.
* Stone Gaze can disable Chen from using 
Hand of God to save himself or his allies.
Medusa
* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.
Winter Wyvern
* Cold Embrace can protect allies from Lone Druid and the Spirit bear, who mainly deal physical damage
* Winter's Curse can turn Lone Druid and the Spirit Bear against his teammates.
Winter Wyvern
* Winter Wyvern's Winter's Curse turns Morphling's high attack damage and attack speed against his targeted teammate.
Medusa
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, 
Luna, 
Naga Siren, Mars, 
Jakiro, 
Venomancer, 
Elder Titan, Faceless Void, 
Rubick, 
Keeper of the Light, 
Pugna, Invoker, 
Spectre, 
Alchemist, Treant Protector, 
Lina, Oracle, Zeus, 
Shadow Shaman, Phoenix, 
Razor, 
Huskar, Batrider, 
Kunkka, Tidehunter, Wraith King, 
Sand King, Medusa, 
Dawnbreaker.
Winter Wyvern
* Many physical-only single-target heroes like Lifestealer, Sven, Wraith King, Phantom Assassin, Templar Assassin can have their damage mitigated by Cold Embrace.
Medusa
* Axe can take advantage of Medusa's awfully low HP to insta-kill her with 
Culling Blade, making it extremely difficult for her to farm for items to compensate for the lack of strength during early and mid-game while Axe is continuously harassing around.
Medusa
* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.
Winter Wyvern
* Heroes who can stop Axe from getting close will severely inhibit his presence in fights: Bristleback, 
Crystal Maiden, Batrider, 
Arc Warden, Winter Wyvern, 
Clockwerk
Winter Wyvern
* Any hero that can nullify effects of Chronosphere: (Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, 
Shadow Demon, 
Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.
Winter Wyvern
* Winter Wyvern's Winter's Curse works very well against the increased attack speed from Bloodlust.
Winter Wyvern
* Broodmother, Nature's Prophet, Phantom Lancer by their nature offer very good target for Splinter Blast and Winter's Curse.
Winter Wyvern
* Winter Wyvern's Arctic Burn can also be a useful tool against Centaur, who generally has very high health. Winter's Curse on Centaur can cause Retaliate to damage allies who are forced to attack him.
Winter Wyvern
* Many physical-only single-target heroes like Lifestealer, Sven, Wraith King, Phantom Assassin, Templar Assassin can have their damage mitigated by Cold Embrace.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: 
Riki, Naga Siren, 
Terrorblade, 
Juggernaut, Spectre, 
Slark.
Medusa
* Medusa's Split Shot and Mystic Snake combined with 
Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of 
Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Additional:
* Medusa's Split Shot and Mystic Snake combined with Mjollnir, a common item for Medusa, will whittle down all of Naga Siren's illusions, including Naga Siren herself.
* Medusa's Stone Gaze can disable Naga Siren even for the duration of Song of the Siren and even if Naga Siren is spell immune, discouraging Naga Siren from even trying to use Song of the Siren to save herself or counter-initiate against Medusa.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Winter Wyvern
* Arctic Burn makes it nearly impossible for Spectre to juke into the trees.
* Cold Embrace negates all of Spectre's physical damage. Furthermore, Cold Embrace will generally outheal 
Desolate.
* Winter's Curse can taunt illusions, not only wasting the entire duration of 
Haunt but also turning its illusions against Spectre's own team.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Winter Wyvern
* Terrorblade and his illusions deal huge damage, which might used against him and his team with Winter's Curse.
Medusa
* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.
Winter Wyvern
* Heroes with abilities that can save teammates are also effective such as Shadow Demon, Dazzle, Oracle, Bane, Pugna, 
Tusk, Winter Wyvern, Io, Underlord, Treant Protector and Keeper of the Light.
Winter Wyvern
* Heavy nukers will do well against Cold Embrace (Lina, Zeus etc).
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Medusa
* Hard carries who just want to farm and be left alone will not appreciate Primal Beast, heroes such as Medusa, 
Drow Ranger...
Winter Wyvern
* Supports who can slow him to the point Trample does very little damage in the lane are also not fun: Lich, 
Ogre Magi, Winter Wyvern.
Winter Wyvern
* Winter Wyvern cannot handle the Zombies created by Undying's Tombstone very well. In most situations, Zombies will have more movement speed than her.
* Undying can gain one or two easy Decay stacks on an ally in Cold Embrace. The ally will still take the damage as well.
Additional:
* Winter Wyvern cannot handle the Zombies created by 
Tombstone very well. In most situations, Zombies will have more movement speed than her.
* Undying can gain one or two easy 
Decay stacks on an ally in Cold Embrace. The ally will still take the damage as well, since it is magical.
Medusa
* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.
Winter Wyvern
* Cold Embrace is no salvation against 
Lucent Beam and 
Eclipse.
* 
Moon Glaives will not hit a hero affected by Winter's Curse, making it weak against allies, but strong versus enemies.
* Luna has better night vision provided by 
Lunar Blessing than Winter Wyvern when affected by Arctic Burn.
Additional:
* Cold Embrace is no salvation against Lucent Beam and Eclipse.
* Moon Glaives will not hit a hero affected by Winter's Curse, making it weak against allies, but strong versus enemies.
* Luna has better night vision provided by Lunar Blessing than Winter Wyvern when affected by Arctic Burn.
Medusa
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, which can cause Luna to struggle greatly in bursting down Medusa and force her to buy Diffusal Blade and it's upgrade Disperser.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Additional:
* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that often goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.
Winter Wyvern
* Heavy nukers will do well against Cold Embrace (Lina, Zeus etc).
Additional:
* Any ally that Winter Wyvern tries to save with Cold Embrace can still be damaged by all of Zeus's spells.
* If Winter Wyvern tries to juke vision by flying up a cliff or in the trees, Zeus can gain vision there with Lightning Bolt or Thundergod's Wrath.
* If Zeus is forced to attack an ally by Winter's Curse, his unimpressive attack damage and attack speed means they won't be hurt much by him. Zeus will also stay near the back of fights away from his allies, making a deadly Curse less likely.
Medusa
* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.
Medusa
* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.
Medusa
* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.
Medusa
* E.M.P. allows Invoker to burn Medusa's mana to weaken
Mana Shield.
E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
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*
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Winter Wyvern
* Cold Embrace is the perfect setup for all his nukes -
Chaos Meteor, 
E.M.P. and especially global 
Sun Strike.