* If Meepo ganks Lion with Poof and Earthbind, he will be an easy target for Earth Spike & AoE Hex from his level 25 talent.

* Medusa lacks mobility or escape mechanisms. Earth Spike and Hex can neutralize her strong damage potential and allow for Lion's team to focus her down.
* Mana Drain is a perfect ability to weaken Medusa's durability as it can quickly drain her Mana Shield, making her far less tanky. Mana Drain can also be used to restore mana of Lion's allies, which can nullify the mana steal from Mystic Snake.
* Mana Drain, along with Hex, destroy illusions instantly, which may be extremely helpfull and efficient against core builders of Manta Style, like Medusa herself.

* Quill Spray usually hits Meepo's clones, although Bristleback cannot turn his back when rooted with Earthbind.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

* E.M.P. allows Invoker to burn Medusa's mana to weaken Mana Shield.
* Medusa's lack of mobility makes her easy to kite with Invoker's spells.
Additional:
* E.M.P. is a large mana burn nuke which can hit Medusa's Mana shield with enough damage to lose even more mana.
* Deafening Blast disarms Medusa's ability to deal pseudo-AOE damage during teamfights.
* Cold Snap allows the opposing team to repeatedly stun Medusa in short succession, preventing her from successfully casting her ultimate due to its long cast time.

* Low-health, normally mobile carries who rely entirely on raw attack damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Fiend's Grip provides mana drain, which can heavily damage Mana Shield and prevent Medusa from using Stone Gaze.
* Even if she does use Stone Gaze, Nightmare can buy enough time to protect allies and reset the fight.
Additional:
* Fiend's Grip leaves Medusa defenseless, since not only does it deal damage, it also drains mana.

* Bulwark blocks the attack from Meepo and his clones.
* Spear of Mars & God's Rebuke prevents Meepo and his clones from initiation or escaping.

* Bulwark can make each of Medusa's attacks target him instead, reducing Medusa's contribution on team fights.
* Spear of Mars stuns Medusa and also pushes her away from teamfights, taking advantage of Medusa's low mobility.
* Arena Of Blood blocks Medusa's attacks from outside the arena.

* Heroes who can stun multiple units at once: Dark Willow, Spirit Breaker, Slardar, Invoker, and Tidehunter.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Dark Seer can take great advantage of Divided We Stand by putting an Ion Shell on a clone in order to harass them effectively.
* Vacuum can take a single Meepo and disable him for Dark Seer and his teammates to take out.

* Focus Fire can quickly attack target Meepo or clones instanly. Additionally, Windranger can use combinated Shackleshot and Focus Fire since Poof wrong landing and stunned from Shackleshot affected Meepo and clones collateral damege from Focus Fire.
* Escaping from Windrun make Earthbind roots can not reach.

* Each of Meepo's clones count as real heroes, meaning that an Echo Slam hitting them will deal catastrophic damage to Meepo and his team.
* Eathshaker's AoE stuns can interrupt Meepo's Poof cast animation.
Additional:
* Echo Slam will deal catastrophic damage against a cluster of Meepos and anyone nearby.
* Aftershock allows Earthshaker's abilities to potentially stun any number of Meepos for a fairly long duration, often enough to finish one off.

* Fatal Bonds links the Meepos together, which combined with area of effect damage or Cleave will be devastating.

* Echo Stomp can completely disable multiple Meepos for 5 seconds.
* Astral Spirit will affect Meepo clones, as they don’t count as illusions. Elder Titan can receive a massive amount of damage, armor and movement speed from each Meepo.
* With Natural Order, Elder Titan’s mere existence causes Meepo to be disadvantaged, due to the aura that completely negates his base armor and magic resistance. Combining Astral Spirit with Natural Order allows Elder Titan to easily kill any Meepo within a second, depending on how much damage he gains from Astral Spirit. This is highly detrimental for Meepo as he is prone to buying items that grant agility like Disperser and Eye of Skadi.
* Earth Splitter deals over 30%/40%/50% of each Meepo’s max hp, and is even stronger if the Meepos are near Elder Titan due to Natural Order.
Additional:
* Meepo lacks the disengages to escape a well-timed Echo Stomp, in particular if Elder Titan is his current target.
* Clones are counted as heroes, increasing massively the power of Astral Spirit's buffs, including Aghanim's Scepter's spell immunity buff.
* Meepo relies heavily on high agility and his mediocre strength gain makes him a very prized target for Natural Order.
* Meepo and his clones like to group up to hunt and kill in teamfights or ganks and can be easily disabled together with Echo Stomp.

* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Additional:
* Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.

* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. He can force her to use Manta Style before he has cast Global Silence and Medusa usually does not want to build Black King Bar.

* Shadow Fiend can easily focus down and kill one of the Meepos.
* The amount of damage from Shadow Fiend's AoE spells makes Meepo vulnerable in every aspect.

* Burrowstrike can stun multiple Meepos, making them vulnerable targets.
* Epicenter and Sand Storm's AoE damage ensures all Meepo clones get damaged, making it hard for Meepo to choose which one to flee as all are taking damage at the same rate.
* Just be aware when using Sand Storm to escape, as Meepo has good AoE damage and disables, which, as explained in the "Bad Against" section, works well against an invisible Sand King.

* With Static Link, Razor can effectively make Medusa useless in teamfights by reducing her main damage output. It can, however, be blocked by a Linken's Sphere.
* Plasma Field allows Razor to get on top of Medusa, slowing her already slow movement speed to a mere crawl.
* Eye of the Storm capitilizes on Medusa's low armor and causes her to be very vulnerable, even through Mana Shield.

* Winter's Curse in late game is pretty much the end for Meepo or any of his nearby allies. Natural counter for Winter's Curse like Linken's Sphere or Lotus Orb is meaningless to her if she can land it on one of Meepo's clones.
Additional:
* Meepo's clones usually gets grouped in teamfight making any of them ideal target for Winter's Curse, forcing Meepo to literally kill himself. Also, unlike other heroes he cannot protect himself with Linken's Sphere.
* While Meepo's clones are grouped up, Splinter Blast will hit almost every clone, slowing Meepo and making him easier to fight.

* All of Jakiro's skills are Area of Effect, which can easily affect all Meepos in a targeted area.

* Flaming Lasso is the perfect tool to isolate a single Meepo and focus him.

* X Marks the Spot is good to prevent a single meepo from escaping from a deadly situation.
* Tidebringer, Torrent and Ghostship destroys Meepo's clones.
Additional:
* Tidebringer's cleave damage can wear down Meepo's clones quickly. It can also give Meepo problems in the lane, due to his melee range and initially low health pool.
* Ghostship and Torrent can effectively disable Meepo while dealing heavy damage.
* X Marks the Spot prevents attempts to escape using Poof.

* Aggressively Poofing and Earthbinding is not going to end well against Venomancer, as he will be an easy target for Noxious Plague.
* Venomancer's constant slows greatly reduce Meepo's mobility.

* Pulse Nova deals an insane amount of damage in an area around him, which can quickly wear down Meepo clones.
* Leshrac can catch multiple Meepos in Split Earth and follow up with the rest of his area damage spells making Meepo unable to get close to Leshrac.
* Diabolic Edict is a strong ability that can wear down a lone Meepo clone quickly.

* Poof combo puts all of the Meepos very close together, making them vulnerable to Frost Blast's AoE slow and multiple bounces from Chain Frost.

* With Nether Swap, Vengeful Spirit can isolate one of the Meepos, making him an easier kill for the team.
* Her Magic Missile gives her an easy way to cancel Meepo's Poof, preventing isolated Meepos from fleeing.

* Medusa's tankiness doesn't help her very much against Fury Swipes in long teamfights.
* With no escape mechanism and a slow movement speed, getting jumped on by Ursa usually spells a quick end for Medusa in the early game.
Additional:
* Ursa's status resistance from Enrage reduces duration of Medusa's Stone Gaze.
* Ursa can stack damage with Fury Swipes easily against her Mana Shield in a prolonged team match.

* Avalanche and Toss prevents Meepo's from using Poof to escape.
* Tiny doesn't need to target the weakest clone while he is affected by Tree Grab.

* Tree Dance and Primal Spring allows him to chase a retreating Meepo.
* Boundless Strike gains critical strike bonuses and Wukong's Command can take down Meepo and his clones very quickly.
Additional:
* Monkey King can gain Jingu Mastery stacks on Meepo’s clones from Divided We Stand.
* Tree Dance allows him to sneak up on and gank a lone Meepo clone.

* Because multiple Meepos tend to clump up, they present an easy target for Timbersaw's many area abilities.
* Although be careful since Timbersaw cannot use Timber Chain to escape if rooted from Earthbind.

* Reactive Tazer can lock multiple Meepos in place and prevent them from Poofing.
* Proximity Mines, Sticky Bomb and Blast Off! can deal heavy magic damage to multiple Meepos.

* Medusa is a fairly immobile hero that deals damage around her with Split Shot. Sniper should outrange her and should stay out of harm's way from Split Shot.
* More importantly, Sniper should have enough attack range to fire at Medusa during her Stone Gaze without turning to stone, so the ultimate is mostly wasted against him.
Additional:
* Sniper can outrange both Medusa's arrows and Stone Gaze, allowing him to focus her down during a teamfight.

* Viper Strike prevents the lifesteal from Ransack.
* Meepo and his clones have a lack of magic resistance, so they're vulnerable to Poison Attack & Viper Strike directed onto one clone.

* Flak Cannon and Call Down will shred Meepo's clones.
* Homing Missile can catch and single out retreating Meepos, making them an easy kill.

* Burning Spear's damage over time can rapidly burn Medusa's mana and health alike.
* Inner Fire can slow and disarm Medusa and also allow Huskar to follow up with Life Break.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

* Troll Warlord can root and deal a lot of damage to a single Meepo while lifestealing through the assault from the other Meepos. Meepo needs expensive items like Ethereal Blade or Heaven's Halberd to be able to fight him.

* Melee heroes who rely on summons, illusions, or clones will trigger Counter Helix more often, thus taking more damage: Meepo, Lycan, Phantom Lancer

Additional:
* The combination of Counter Helix and Berserker's Call can disable multiple Meepos and deal heavy area damage.
* Axe's natural high survivability makes it difficult to burst him down with Poof or chip away at his health with Ransack.

* Axe can take advantage of Medusa's awfully low HP to insta-kill her with Culling Blade, making it extremely difficult for her to farm for items to compensate for the lack of strength during early and mid-game while Axe is continuously harassing around.

* Heroes who can stun multiple units at once: Dark Willow, Spirit Breaker, Slardar, Invoker, and Tidehunter.

Additional:
* Casting Bramble Maze on top of Meepo guarantees a root, as it is nearly impossible to leave the thorns with all of Meepo's clones.
* Terrorize and Cursed Crown offer great disables against the grouped Meepos and can prevent them from using Poof to escape.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* Tether helps Io escape from Earthbind even if Meepo has Blink Dagger.
* Io's Spirits can pressure Meepo while laning and will usually hit at least one of his clones.

* Medusa cannot chase Slark in any way and has no disable beyond her ultimate, making her unable to stop him getting away and regenerating before coming back to finish her off.
* Essence Shift particularly removes 1 intelligence point per hit, thus lowering Medusa's mana pool's cap and leaving her much more vulnerable in prolonged fights.
Additional:
* Medusa is especially vulnerable to Essence Shift, as both strength and intelligence contribute to her effective HP, while agility contributes to her damage.
* Dark Pact when timed right can be used to dispel Stone Gaze right after it petrifies Slark, allowing him to keep attacking Medusa throughout the duration.

* Light Strike Array can catch Meepo and his clones off-guard if he tries to gank Lina with Earthbind & Poof.
* Laguna Blade can quickly kill Meepo and his clones before they escape with Poof.

* Sleight of Fist combined with Battle Fury, Maelstrom and Daedalus will allow Ember Spirit to make a quick work of Meepo if his clones are crowded around each other.
* Searing Chains interrupts Meepo's initiating because Meepo's clones do not have spell immunity.
Additional:
* Meepo is quite fragile in the early game and can be easily taken down by Flame Guard's and Searing Chains' damage. Later on, Meepo is very vulnerable to Sleight of Fist's damage due to Battle Fury's cleave on multiple Meepos.

* He can use either his own or his double's Flux to bypass the spellblock from Linken's Sphere, using the leftover Flux + Spark Wraith to slow Medusa's already low move speed to a crawl.
* Arc Warden has a farming advantage with double Hand of Midas, and can generally bully Medusa with other items that benefit from duplication.

* Void Spirit can dodge Earthbind with Dissimilate and Astral Step, giving him a good chance to escape. If he gets caught anyways, Resonant Pulse allows him to retaliate.

* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and Anti-Mage.

* Enchantress's Untouchable slows down Meepos attacks and Impetus can deal heavy pure damage to a single Meepo, however once Meepo has closed the gap she is an easy target for Poof.

* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include Spectre, Shadow Demon, Phantom Lancer, Naga Siren, Chaos Knight, Terrorblade) or bring other units into the fight (such as Nature's Prophet, Lone Druid, Chen, Enchantress, Meepo and Arc Warden).

* Heroes who can stun multiple units at once: Dark Willow, Spirit Breaker, Slardar, Invoker, and Tidehunter.

* Lifestealer is not affected by Earthbind or Poof during Rage, making him a difficult target to work around.

* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.

* Pangolier's arsenal deals heavy damage in a wide area, make him deadly even for a Meepo with a high magic resistance.
* Shield Crash can easily give him a ridiculous 80% damage resistance (Becomes 100% if Pangolier gets his +5% Shield Crash talent, Or there is 5 Meepos), resulting in a near unkillable Pangolier in a short amount of time.
* Rolling Thunder disrupts Meepo's initiation or escaping.
* Swashbuckle can hit all of Meepo clones.
* Lucky Shot can disarm Meepo's clones.
Additional:
* Shield Crash gains its damage reduction bonus from all Meepo clones, and can be used even when rooted, allowing Pangolier to gain a massive amount of damage reduction (even more than 100%).
* With too many clone running around during combat, it is almost impossible for Meepo to avoid Rolling Thunder or Swashbuckle.
* Still, remember that a lone Pangolier can never escape from a ganking Meepo.

* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.

* Heroes who can stun multiple units at once: Dark Willow, Spirit Breaker, Slardar, Invoker, and Tidehunter.

* Other heroes who has armor and slow debuffs won't allow Medusa to disengage from combat: Tidehunter, Bristleback, Slardar.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

* Besides Lone Druid and Meepo, Doom is potentially good versus every hero since Doom will render any hero helpless for up to 16 seconds. This is particularly true for fragile heroes that heavily rely on mobility to stay alive.

* Heroes without blink mechanisms or spell immunity will have a hard time positioning against Pit of Malice: Sven, Tiny, Wraith King, Dragon Knight, Meepo, Doom, Bounty Hunter, Dark Seer, Undying, Alchemist, Legion Commander.

* Anti-Mage easily destroys Mana Shield with Mana Break, especially once he has Manta Style.
* Anti-Mage effectively avoids Stone Gaze with Blink, and can reinitiate after its duration is over.
Additional:
* Mana Break burns Medusa's mana easily, especially when coupled with a Manta Style.
* Can easily initiate on Medusa with Blink, burning her mana or forcing her to use Stone Gaze.
* Mana Void is effective against Medusa's big mana pool and mana usage, presenting a huge hazard to Medusa's allies around her since her Mana Shield still gives her some protection if she has mana.

* With Smoke Screen, Riki will silence and catch Medusa in a surprise with high miss chance flushing her from positions easily in team fights.
* He can deal a huge amount of damage through Cloak and Dagger, even through Mana Shield.

* Phantom Lancer with Diffusal Blade will very quickly burn Medusa's mana, making Mana Shield significantly less effective.
* Doppelganger's 1 second invulnerability can be used to dodge Medusa's petrification from Stone Gaze, as well as Mystic Snake.
* Phantom Lancer's illusions outnumber Medusa's targets from Split Shot, likely shielding his team in the process.

* Heroes that have doubles or clones such as Arc Warden, Meepo or Lone Druid are vulnerable to Muerta's Gunslinger.

* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.

Additional:
* Meepo is vulnerable to area damage and disables from Magnus himself as well as his team through Empower.

* Heroes with extremely slow movement speed will cripple against Solar Bind: Medusa, Viper

Additional:
* Will-O-Wisp will keep Medusa busy after she got hit by Blinding Light.

* Heroes that build Diffusal Blade or can fit it well into their item build will also make Medusa much less tanky: Riki, Naga Siren, Terrorblade, Juggernaut, Spectre, Slark.

* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away all of Medusa's mana.
Additional:
* Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.

* Every Meepo clone adds to Thirst's bonuses.
* Bloodseeker can chase down retreating clones when Meepo tries to cycle weaker clones away from combat.

* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.

* Great Cleave will devastate Meepo's clones. Against a closely packed group, Sven does not even need to target the clone with the lowest health.
Additional:
* Great Cleave and God's Strength can take down Meepo and his clones very quickly.
* The lack of spell immunity for Meepo's clones makes them vulnerable to Storm Hammer.