* Necrophos struggles at clearing away durable illusions or summons. Meepo can overwhelm Necrophos with his many duplicates, especially in the later stages of the game, and his Earthbind will prevent Necrophos from getting away, even if he casts Ghost Shroud.
* Meepo's high burst damage from Poof can make it difficult for to Necrophos to stay alive, and as Necrophos excels in extended fights, he will not be able to do as much damage as he intends to.

* Mana Shield tanks most of the damage from Reaper's Scythe; with sufficient mana, the kill threshold drops significantly.
* Necrophos has a movement speed equal to Medusa, and is easy to chase down with a slowing item in Medusa's inventory.

* When Legion Commander uses Duel on one Meepo, he can use his other Meepos to kill her. If he wasn't dueled, he can help the teammate who was duelled to give the teammate the damage instead of Legion Commander.
* However, if Legion Commander picked up an Aghanim's Scepter and she duels one Meepo, that might be the end of Meepo if Legion managed to gather enough damage from previous duels.

* Mana Shield makes Medusa very hard to take down in Duels.
* Stone Gaze stops Legion Commander from Dueling altogether, regardless of who she targets.

* Thundergod's Wrath strikes only the first Meepo.
* Zeus has low mobilty so consecutive Earthbinds are easy to hit and he'll quickly die from Poofs.

* Heroes with a lot of burst damage, especially those who rely on casting spells: Lina, Zeus.

* Meepo can quickly destroy Tombstone thanks to Divided We Stand.

* Split Shot can destroy Tombstone Zombies and Tombstone itself while still damaging heroes.

* Heroes that can overwhelm Visage by sheer number like Chaos Knight, Meepo, Terrorblade and Phantom Lancer.

* Visage's familiars are easy targets to Split Shot.
* Mana Shield will resist Soul Assumption instances without effort.

* Meepo can quickly kill Enchantress with a Poof combo, rendering Untouchable useless.

* Enchantress often has a small army of neutral creeps, allowing Medusa to hit her with a later bounce of her Mystic Snake.

* Earthbind's root prevents/interrupts Charge of Darkness.
* As a single target focused hero without much damage output, Spirit Breaker is ineffective in general against Meepo. Consider upgrading Nether Strike with Aghanim's Scepter to spam AoE stuns against Meepo clones.

* If Medusa activates Stone Gaze, the charge will inevitably fail.
* Mana Shield and overall tankiness allows Medusa to easily survive Spirit Breaker's initiation.

* Even though Moon Glaives can bounce between Meepo and his clones, Meepo can tank Eclipse because of his clones.
* Earthbind takes away Luna's mobility advantage.
* Meepo can shutdown Luna's split-push ability with his global presence.
* For the same reasons, Meepo makes a very powerful ally for Luna when they are in the same team.

* Should Luna choose to buy Manta Style, Medusa will be able to kill illusions from them with Split Shot and Mjollnir, which is a common item on Medusa.
* Mystic Snake allows Medusa to easily harass Luna and steal mana from her, preventing Luna from retaliating with Lucent Beam.
* Medusa can survive Eclipse thanks to Mana Shield, and since Luna is not a hero that goes for Diffusal Blade, she will struggle greatly in bursting down Medusa.
* Even with Black King Bar, Medusa's Stone Gaze will still be able to disable Luna, which could even discourage her from counter-initiating with Eclipse.
* For the same reasons, Medusa makes a very powerful ally for Luna when they are in the same team.

* Earthbind disables Waveform, effectively keeping Morphling in place for an extended period of time, allowing Meepo to deal considerable damage with Poof.

* Chain of Earthbinds prevents her from using Blink, allowing Meepo to quickly kill her with Poof and attacks.
* Meepo tends to buy items with attributes, mitigating Queen of Pain's magical burst.
Additional:
* Meepo is the hard counter for Queen of Pain - chaining Earthbinds prevents her from using Blink for a long time, and without any other escape options, Queen of Pain cannot survive several Poofs and attacks.
* Meepo tends to build items with attributes, mitigating Queen of Pain's magical burst.

* Poof will destroy Shadow Demon's illusions created by Disruption and quickly escapes from Shadow Poison & Demonic Purge.

* Ogre Magi has single-targeted magical-only damage and disables and is less effective against Meepo's clones.

* Lifestealer's Rage and Open wounds become useless when Meepo has 4 or more clones, as Ransack will heal Meepo too quickly for Lifestealer to take down.

* Lifestealer's low mobility makes him easy to kite.
* Stone Gaze pierces Rage, wasting its cooldown and making Lifestealer unable to fight.

* Earthbind, like any root, inhibits usage of Ball Lightning, eliminating Storm Spirit's mobility.

* With all 5 Meepos available, all of Shaman's wards will be disposed of very quickly.
* All of Shaman's disables are based around single target control, and he can at most only disable two Meepos, allowing the rest to easily lay waste to him, be it during the channel duration of Shackles or by using Earthbind.

* Earthbind can prevent Phoenix from using Icarus Dive, the only escaping mechanism of this hero.
* Heavy burst damage from Poof can easily kill Phoenix even when it slows down all the Meepos with Fire Spirits.
* Meepo's clones destroy the Phoenix Sun from Supernova in no time, even when they are slowed down by Fire Spirits.
* Meepo's naturally high magic resistance gives Phoenix a hard time with bursting him down. He can even turn the tide if Icarus Dive is on cooldown.
Additional:
* Meepo is unlike any other multi-unit enemy Phoenix may face in the battlefield. Unlike illusion-based heroes like Phantom Lancer or Chaos Knight, Meepo's clones are not illusions, meaning they can deal full damage to the Phoenix Sun if all four (or five) are present.

* Naga Siren's Song of the Siren may be useful but Poof will destroy all of her illusions.

* Medusa's Split Shot will whittle down all of Naga Siren's illusions, including Naga Siren herself.

* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake

* Nature's Prophet is heavily countered by Meepo, not only Meepo can kill the treants with a single Poof, but he can also stop Nature's Prophet from using Teleportation, and can gain vision inside Sprout.

Additional:
* Meepo can net Nature's Prophet's treants with Earthbind and then Poof them, putting an end to his pushing.
* Skilled Meepos can rival and even exceed Nature's Prophet's global presence by combining Poof with Boots of Travel, meaning that he can not only stop his push, but also can kill him if he is not careful.

* Pugna's Nether Ward doesn't really hurt Meepo since he usually buys attribute items to tank up and can be killed very quickly by 4 clones. Decrepify can amplify Poof's damage should Pugna use it to avoid Meepo's right clicking.

* Heroes with powerful rooting abilities will disable most of Pangolier's skills, a bonus point if it pierces spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: Treant Protector, Meepo, Crystal Maiden, Dark Willow, Underlord, Naga Siren

* Split Shot will keep attacking Pangolier even when he is rolling around.
* Stone Gaze stuns Pangolier during Rolling Thunder, or forces him to roll away.

* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna

* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with Hookshot) can easily avoid Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.

* Meepo has a better advantage in farm with Divided We Stand, as well as having a higher attack speed due to his tendency to build items that give attributes. In addition, Wraithfire Blast stuns only one target, and choosing to engage one Meepo will most certainly mean engaging them all.

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Skywrath Mage's abilities are single targeted and he can't use Mystic Flare to its fullest potential, since all Meepos spread the damage between them. He also has no disables to prevent Meepo from Poofing to another one (unless he can get Ancient Seal off first).

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Heroes with strong area-of-effect damage can make quick work of Chen's converted creeps and at same time gain farm: Magnus, Jakiro, Shadow Fiend, Kunkka, Luna, Dragon Knight, Medusa, Alchemist.

* Night Stalker's most skills are single targeted which allows other Meepos to Poof, Earthbind and kill him.

* Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.

Additional:
* Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by Poof and Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.

* Tinker who can't fight multiple heroes will suffer greatly against Ransack and Earthbind.

* Doom does not disable Mana Shield. As such, Doom's damage is largely mitigated by her mana shield. Additionally, Medusa is not reliant on her abilities to be effective during a teamfight, making Medusa an unproductive hero to target.
* Medusa is an ideal Linken's Sphere carrier. Should one be purchased, and without any additional disables, Doom may find that few opportunities exist to effectively lockdown, disable, and kill Medusa.

* Mana Shield reduces the effectiveness of Counter Helix.
* Stone Gaze makes it very difficult for Axe to initiate on Medusa and her allies.

* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* Medusa can also kill Eidolons with her Mystic Snake that can also greatly damage Enigma and drain some of his mana.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult, because Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from even trying to initiate with Black Hole.
Additional:
* Medusa's Split Shot can make quick work of Enigma's Eidolons and take advantage of their considerable bounty.
* If Medusa activates Stone Gaze at the start of a fight, it can make initiating — and landing an effective Black Hole exceedingly difficult.
* Stone Gaze can cancel Enigma's Black Hole even through spell immunity, which can discourage Enigma from initiating with Black Hole.

* Slardar does not do well against multiple targets, as his only way to damage multiple targets is Slithereen Crush.
* Meepo's Earthbind will root Slardar, making him unable to chase/escape for the time being. Also, Poof's low cooldown and high damage can burst Slardar down rather quickly.

* Medusa cares less than other heroes about armor reduction, since Mana Shield blocks 70% of all damage without taking armor/magic resistance into consideration. This makes 60% of your Corrosive Haze ineffective until Medusa's mana is drained.

* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots

* Heroes with disables that ignore spell immunity will render Phantom Assassin quite useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa.

* Stone Gaze allows Medusa to easily kite and kill Sven.
* Mana Shield negates much of Sven's burst damage.
Additional:
* Mana Shield makes it very hard for Sven to burst her within Storm Hammer's stun duration.
* Stone Gaze makes it very difficult for Sven to manfight Medusa at any stage of the game.
* Mystic Snake can slow Sven down enough for allies to capitalise on his commitment in a fight.

* Mana Shield makes it very difficult for Bloodseeker to gain his Thirst bonuses.
* Rupture rarely kills Medusa through Mana Shield.

* Heroes that can jump and kill him: Meepo, Clinkz, Templar Assassin

* Juggernaut's Omnislash is meaningless for Meepo who can share the damage across clones to save other allies.

* Poof will destroy Phantom Lancer's illusions within a short time.
* Earthbind prevents Phantom Lancer from using Doppelganger.
Additional:
* Poof from multiple Meepos will destroy illusions quickly.
* Earthbind's area root can catch Phantom Lancer in a group of illusions and prevent him from using Doppelganger for a long time.
* Meepo aims to end the game as early as possible, while Phantom Lancer is a lategame hero.
* This also means that, in the late game, Meepo stands no chance against Phantom Lancer.

* Heroes with Linken's Sphere as core item: Weaver, Morphling, Medusa.

* Spectre's Haunt with Radiance may be useful for countering Meepo but if Meepo finds the real one, Spectral Dagger is useless. Non-Black King Bar heroes like her will suffer from all of Meepo's abilities. Meepo is also a very large counter as Spectre takes a long time to come online, normally farming in the jungle or in lane, which makes her an easy target for Meepo ganks.

Additional:
* Poof combined with Earthbind can be used to easily lockdown and burst Spectre down.
* As Meepo's playstyle is often to come online early to mid game and take over the whole game, Meepo will often be much further ahead of Spectre in farming.
* Meepo's global map presence allows him to effectively hunt for Spectre and disrupt her farm.
* Spectre has no strong AOE abilities or way to control or lock down Meepo.

* Flux is severely impaired against Meepo because of Divided We Stand.
* Meepo's farming speed and early powerspikes allows him to pressure Arc Warden before he is capable of fighting effectively.
* Without Black King Bar, Earthbind and Poof can finish Arc Warden quickly before he has time to do much.

* Multiple Earthbinds allows Meepo to lock down Anti-Mage almost indefinitely.
* Meepo's clones can only use their mana for Poof, keeping their mana pool nearly full and thus making them a bad target for a Mana Void.
Additional:
* Earthbind can prevent Anti-Mage from using Blink, allowing Meepo to kill him with attacks and Ransack.

* Earthbind prevents Broodmother from escaping Meepo's attacks.
* Poof will quickly clear any nearby spiders.
* Broodmother wants to pick off single target heroes. With Meepo's Divided We Stand, it gets a lot harder once every Meepo Poofs in.