* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with Aphotic Shield, or remove it from himself with Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.

* Primal Roar can be instantly dispelled by Aphotic Shield.
* The debuffs from Wild Axes and Poison from Call of the Wild: Boar can also be dispelled by Aphotic Shield.
Additional:
* Aphotic Shield effectively nullifies Primal Roar's single-target initiation on allies.
* Even being initiated by Primal Roar, Borrowed Time can make Abaddon extremely difficult to kill.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* False Promise effectively nullifies Primal Roar's single-target initiation on allies.
* Purifying Flames kills Beastmaster's Hawk instantly and Boar with two casts.

* If Slark sees the Sacred Arrow before it hits him, he can use Dark Pact to remove it a moment later.
* Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter​ combo with Shadow Dance.

* Heroes with strong dispels can remove Primal Roar's stun: Abaddon, Slark, Oracle.

* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.

* Track detects Mirana and her allies during Moonlight Shadow.

* Having many summons out will cause Echo Slam to deal extra damage.

* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Additional:
* Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and Light Strike Array can disable Mirana if she tries to Leap away.
* Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.

* Illuminate clears Beastmaster's summons and is effective against his push.

* Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* Shackleshot through tree with Focus Fire via Aghanim's Scepter​ combo can kill Mirana quickly, before using Leap or Moonlight Shadow.

* Puck can initiate on Mirana with Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.

* Cold Embrace mitigates Primal Roar's single-target initiation on allies.
* Winter's Curse can turn Beastmaster's summons and Inner Beast against his teammate.
Additional:
* Beastmaster's summons and Inner Beast are very useful to attack his cursed teammate.
* Cold Embrace effectively mitigates Primal Roar's single-target initiation on allies.

* Reactive Armor is very effective against Beastmaster's summons during laning stage and entire game.
* Timbersaw can quickly clear Beastmaster's summons with his nukes.

* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, Magnus

* Untouchable negates Inner Beast's attack speed bonus, making her hard to kill even if stunned by Primal Roar.
* Enchantress can also take control of Beastmaster's summons.
Additional:
* Enchant can control Beastmaster's boars, mitigating his effectiveness during the laning stage and teamfights.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like Storm Spirit, Mirana, Anti-Mage and others won't be able to do much if they're caught.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Heroes with AoE abilities are a bane to Beastmaster's summons: Storm Spirit, Magnus, Pangolier.

* Heroes with summoned units don't fare well against Dawnbreaker. (Phantom Lancer ,Beastmaster ,Lycan)

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* Heroes with Linken's Sphere as core item: Weaver, Morphling, Medusa.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,Beastmaster

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes with AoE abilities are a bane to Beastmaster's summons: Storm Spirit, Magnus, Pangolier.

* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Single-target disablers will have difficulty locking down a Chaos Knight with Phantasm active: Bane, Beastmaster, Bloodseeker, Clockwerk, Doom, Shadow Shaman.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Heroes with Linken's Sphere as core item: Weaver, Morphling, Medusa.

* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Additional:
* Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.

* The long silence of Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With Dark Ascension and Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.

* Chen can take control of the Boar from Call of the wild Boar at any time.

* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.

* Thirst detects Mirana or her ally at low health during Moonlight Shadow.
* Rupture deals high damage when Mirana uses Leap.
Additional:
* Rupture can quickly kill Mirana if she tries to Leap away.
* Thirst detects Mirana and her allies during Moonlight Shadow.