Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: 
Anti-Mage, 
Queen of Pain, 
Storm Spirit, 
Riki.
Brewmaster
* Blinking heroes like Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.
Mirana
* Thirst detects Mirana or her ally at low health during 
Moonlight Shadow.
* Rupture deals high damage when Mirana uses 
Leap.
Additional:
* 
Rupture can quickly kill Mirana if she tries to Leap away.
* 
Thirst detects Mirana and her allies during Moonlight Shadow.
Mirana
* 
Track detects Mirana and her allies during Moonlight Shadow.
Mirana
* Puck can initiate on Mirana with 
Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in 
Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with 
Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving 
Sacred Arrow, and also can avoid 
Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.
Mirana
* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Additional:
* 
Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place 
Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
Mirana
* The long silence of 
Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With 
Dark Ascension and 
Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Mirana
* Heroes with silences and hard stuns such as 
Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Brewmaster
* 
Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Lion has used all his crowd control before entering a fight. His direct magic burst also makes Brewmaster's Drunken Brawler worthless versus Lion.
Mirana
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like 
Mirana's Sacred Arrow or 
Leshrac's 
Split Earth, or combos like 
Kunkka's 
X Marks the Spot into 
Torrent.
Brewmaster
* 
Exorcism kills Primal Split's units very quickly.
Brewmaster
* 
Ancient Seal's instant cast time will often silence Brewmaster before he can do anything.
* Brewmaster also has no defense against Skywrath Mage's massive magical damage.
Mirana
* If Slark sees the Sacred Arrow before it hits him, he can use 
Dark Pact to remove it a moment later.
* 
Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's 
Aghanim's Scepter combo with 
Shadow Dance.
Brewmaster
* Brewmaster is slow and has low armor, making his laning stage very difficult against Geminate Attack.
* Apart from the slow moving 
Hurl Boulder, which can be disjointed, he has no control to catch Weaver.
Mirana
* 
Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* 
Shackleshot through tree with 
Focus Fire via Aghanim's Scepter combo can kill Mirana quickly, before using Leap or Moonlight Shadow.
Mirana
* 
Doom completely takes Mirana out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Mirana
* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Additional:
* 
Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and 
Light Strike Array can disable Mirana if she tries to Leap away.
* 
Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.
Mirana
* Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.
Additional:
* 
Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by 
Poof and 
Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Mirana
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, 
Outworld Destroyer, 
Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Low-health, normally mobile carries who rely entirely on raw attack damage are vulnerable to Bane's nukes and disables: Anti-Mage, 
Clinkz, 
Drow Ranger, 
Faceless Void, 
Gyrocopter, 
Juggernaut, 
Meepo, Mirana, 
Monkey King, 
Morphling, 
Phantom Assassin, 
Phantom Lancer, Riki, 
Shadow Fiend, 
Slark, 
Sniper, 
Terrorblade, 
Troll Warlord, 
Weaver.
Brewmaster
* After Brewmaster has committed Thunder Clap and Cinder Brew to gank, Bane can use 
Nightmare on Brewmaster to wait out the debuffs, and might even turn the tables by buying time for allied reinforcements.
* Bane can also prevent Brewmaster from using Primal Split with his long disables.
Mirana
* Mirana can build Eul's Scepter of Divinity and Sacred Arrow can help her's allies canceled from 
Fiend's Grip.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Mirana
* Heroes with spells that negate invisibility such as 
Bounty Hunter, 
Zeus and 
Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, 
Nature's Prophet.
Mirana
* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like Storm Spirit, Mirana, Anti-Mage and others won't be able to do much if they're caught.
Brewmaster
* Heroes with strong team-fight abilities (especially ultimates) like 
Tidehunter, 
Brewmaster, 
Death Prophet, etc.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Mirana
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from 
Spawn Spiderlings, which in combination with the huge speed provided by 
Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys 
Orchid Malevolence and it's upgrade 
Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to 
Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, and prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Brewmaster
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: 
Broodmother, 
Enigma, Nature's Prophet.
Mirana
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from 
Eclipse with Moonlight Shadow, smart Luna can buy 
Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Mirana
* A couple of long-range heroes with excellent laning like Mirana, 
Lina, 
Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Brewmaster
* Blinking heroes like Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.
Mirana
* Counterspell does not protect Anti-Mage from Sacred Arrow.
* Moonlight Shadow can help her allies avoid Mana Break and Mana Void.
* Blink's cooldown isn't short enough to escape from Leap, especially when she has the extra charge from 
Aghanim's Shard.
Additional:
* Combo items for Mirana 
Rod of Atos can upgrade to 
Gleipnir and Sacred Arrow before and during Anti-Mage build item 
Manta Style cooldown can easy penetrates Counterspell broken.
* Charge for Leap can Mirana easily faster escaping.
* Moonlight Shadow it can disappear anytime and Anti-Mage can not fight.
Mirana
* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.
Brewmaster
* 
Primal Split makes Brewmaster invulnerable for the duration, rendering effects of Cold Feet and Ice Blast useless.
* 
Dispel Magic can dispel Cold Feet from allies.
* Brewmaster can easily run Ancient Apparition down with the slow from 
Thunder Clap and 
Cinder Brew.
Mirana
* Heroes that cannot move in fights such as a 
Dueling Legion Commander or anyone channeling a spell like 
Bane, 
Pudge, or Enigma are easy Sacred Arrow targets.
Brewmaster
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.
Mirana
* Techies spends lots of time standing still planting stacks of 
Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use 
Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.
Brewmaster
* Cinder Brew and 
Drunken Brawler makes it hard for Monkey King to stack Jingu Mastery.
* 
Cyclone can remove Monkey king for 6 seconds if his allies lack dispels.
* Dispel Magic can dispel Jingu Mastery's bonuses.
Mirana
* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If 
Frostbite has already been used, Mirana can Leap away even when slowed by 
Crystal Nova or 
Freezing Field.
Brewmaster
* Storm's Dispel Magic combined with Thunder Clap deals high damage against Chaos Knight's illusions even in the late game.
* Chaos Knight's reliance on physical damage is easily hindered by Drunken Brawler.
* Chaos Knight's lack of area effect and mobility makes him easily overwhelmed by Primal Split.
Additional:
* Dispel Magic from {U:Storm} can instantly kill Phantasms early on, and can still deal a lot of damage to them late game, revealing the real Chaos Knight.
Mirana
* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* 
Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
Mirana
* Leap allows Mirana to easily escape Torrent and Ghostship.
Brewmaster
* Dispel Magic from {U:Storm} instantly removes Heavenly Grace and Guardian Angel from Omniknight's allies in its radius of effect.
Mirana
* Mirana can use Leap to jump right next to Drow Ranger or can approach her while under cover of the invisibility granted by Moonlight Shadow, which cancels the bonus granted to Drow Ranger by 
Marksmanship.
* Her low health makes her easy to burst down with Mirana's spells, especially with Aghanim's Scepter.
* Mirana can dodge 
Gust with good reaction time, or Leap away if Drow tries to slow her without Gust.
Brewmaster
* The three Primal Split brewlings all attacking Templar Assassin at once will remove her 
Refraction quickly, especially with Fire's Permanent Immolation.
* Templar Assassin has no way to stop Brewmaster from using Primal Split by herself, and may get unlucky and miss her 
Meld if trying to burst him during her ally's disable.
Brewmaster
* Cyclone from Storm in Primal Split can waste Nyx's Spiked Carapace, since its duration is shorter than the Cyclone's.
Brewmaster
* If Ursa uses 
Enrage Brewmaster can use Cyclone to render him harmless during his ultimate.
* Brewmaster has two spells to slow down Ursa, allowing his team to kite around him easily.
Brewmaster
* Brewmaster can make the Spirit Bear a much smaller threat with Cinder Brew.
* Cyclone removes the bear from a fight so that his team can easily focus on the hero.
* While most heroes would be worn down by a Spirit Bear 
Radiance in the time it takes to kill Lone Druid, Brewmaster is protected in Primal Split.
Mirana
* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys 
Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and 
Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.
Brewmaster
* Brewmaster can use Cyclone to disable Huskar's healer for much longer than most other heroes can, to make Huskar vulnerable.
* Huskar has no way to stop Brewmaster from using Primal Split by himself, but can cut a good amount of his high health away if Huskar's team wants to burst Brewmaster down during a different disable.
Brewmaster
* {U:Earth} has passive 
Spell Immunity, allowing him to walk into the Echo Stomp radius to stun Elder Titan with his Hurl Boulder.
* {U:Storm}'s Cyclone can cancel the channeling of Echo Stomp and take Elder Titan out of the fight for {show:A|Storm|Cyclone|value2} seconds.
Brewmaster
* In general, Brewmaster's Cinder Brew and Thunder Clap makes him good against physical damage carries: 
Ursa, Clinkz, Faceless Void, Troll Warlord, 
Templar Assassin, Phantom Assassin.
Mirana
* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: 
Lifestealer, Doom, Mirana, Clinkz.
Brewmaster
* In general, Brewmaster's Cinder Brew and Thunder Clap makes him good against physical damage carries: Ursa, Clinkz, Faceless Void, Troll Warlord, Templar Assassin, Phantom Assassin.
Mirana
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: 
Arc Warden, 
Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, 
Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates difficult targets to hook.
* Sacred Arrow can be used to cancel Dismember from long distances.
Mirana
* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.
Brewmaster
* In general, Brewmaster's Cinder Brew and Thunder Clap makes him good against physical damage carries: Ursa, Clinkz, Faceless Void, Troll Warlord, Templar Assassin, Phantom Assassin.
Brewmaster
* Brewmaster with Primal Split
* Heroes that can dodge Glimpse:
* 
Puck with Phase Shift
* Riki with 
Tricks of the Trade
* Phantom Lancer with 
Doppelganger
* 
Ember Spirit with 
Sleight of Fist and 
Activate Fire Remnant
* 
Chaos Knight with 
Phantasm
* 
Naga Siren with 
Mirror Image
* 
Tusk with 
Snowball
* Juggernaut with 
Omnislash
* Brewmaster with Primal Split
* Lifestealer with 
Infest
* 
Phoenix with 
Supernova
Brewmaster
* Heroes with area dispel can kill multiple skeletons at once: Brewmaster, Oracle.
Mirana
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, 
Magnus
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or 
Enchantress.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Brewmaster
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.
Mirana
* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, 
Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Brewmaster
* In general, Brewmaster's Cinder Brew and Thunder Clap makes him good against physical damage carries: Ursa, Clinkz, Faceless Void, Troll Warlord, Templar Assassin, Phantom Assassin.
Additional:
* Thunder Clap and Drunken Brawler prevent Faceless Void from maximising his damage potential in fights.
* Cyclone disables Faceless Void during Chronosphere or in general.
Mirana
* Mirana's Leap is ineffective if Lycan uses 
Shapeshift. It also allows him to dodge Sacred Arrow.
Brewmaster
* Brewmaster can waste a large portion of Lycan's ultimate by putting him in Cyclone.
* Lycan has no way to stop Brewmaster from using Primal Split by himself.
* Lycan's team often tries to push towers as a group, and Brewmaster excels at winning teamfights while trying to defend a tower.
Mirana
* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with 
Aphotic Shield, or remove it from himself with 
Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.
Brewmaster
* {U:Storm} can use Cyclone on Abaddon when he activates Borrowed Time, wasting its duration.
* Drunken Brawler and Thunder Clap hinder Abaddon from applying Curse of Avernus' silence on him.
Additional:
* Dispel Magic can remove Abaddon's Aphotic Shield or 
Curse of Avernus on an allied hero.
* Cyclone's lengthy duration wastes much of Borrowed Time's duration.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Brewmaster
* 
Hex's instant cast time will force Brewmaster into the awkward situation of needing some form of spell immunity or block to prevent being immediately hex upon blinking in, or wait until Shaman has used all his crowd control before entering a fight.
* Brewmaster also has no defense against Shadow Shaman lockdowns.
Mirana
* Mirana can disturb Shadow Shaman's channeling even if he is under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying towards Shadow Shaman can continue for the whole match.
Mirana
* Heroes that can protect or dispel stunned allies such as
Legion Commander, 
Outworld Destroyer, 
Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Brewmaster
* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.