Mirana
* 
Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.
Additional:
* 
Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by 
Poof and 
Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Broodmother
* Earthbind prevents Broodmother from escaping Meepo's attacks.
* Poof will quickly clear any nearby spiders.
* Broodmother often picks off single target heroes. With Meepo's 
Divided We Stand, it gets a lot harder once every Meepo Poofs in.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: 
Anti-Mage, 
Queen of Pain, 
Storm Spirit, 
Riki.
Broodmother
* 
Ball Lightning and 
Electric Vortex will catch Broodmother before she has a chance to retreat, and is able to catch her through the trees.
* Conversely, Ball Lightning also allows him to easily escape Broodmother, as she has no way to prevent him from using it before getting 
Orchid Malevolence.
Mirana
* Puck can initiate on Mirana with 
Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in 
Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with 
Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving 
Sacred Arrow, and also can avoid 
Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot 
Leap away.
Broodmother
* Mass summoning heroes: 
Broodmother, 
Nature's Prophet and 
Enigma all have summons Puck can clear with Illusory Orb and Waning Rift instantly, due to their summons having low health.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: 
Shadow Demon, 
Phantom Lancer, Nature's Prophet.
Broodmother
* Heroes with no AoE abilities will struggle against Phantom Lancer: 
Phantom Assassin, Broodmother
Mirana
* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with 
Aphotic Shield, or remove it from himself with 
Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's 
Aghanim's Scepter combo.
Broodmother
* 
Echo Stomp can impede Broodmother's ability to push towers due to its low cooldown and long sleep duration.
* 
Astral Spirit can provide Elder Titan large amounts of damage, armor, and movement speed from her spiderlings.
* 
Natural Order negates Broodmother and her spiderling's base armor and magic resistance, increasing most damage dealt to them.
Broodmother
* Berserker's Call can catch Broodmother in her web, as well as groups of spiderlings. This is particularly effective when Broodmother attempts to push towers with her spiderlings.
* Counter Helix destroys spiderlings very quickly and earns Axe a good deal of gold.
Additional:
* 
Berserker's Call forces Broodmother and her spiderlings to attack, allowing for large amounts of pure damage to be done through 
Counter Helix.
Broodmother
* 
Sleight of Fist keeps Ember Spirit invulnerable until he hits every unit in its area of effect allowing him to stall for large amounts of time against Broodmother and her large amounts of spiderlings, or potentially damaging them enough if equipped with an item to improve wave clearing such as 
Battle Fury or 
Maelstrom to prevent her pushes entirely.
* 
Flame Guard will damage any of Broodmother's spiders in an area, deterring her from attempting to kill him. It can also be used during Sleight of Fist to amplify damage done.
* 
Fire Remnant allows Ember Spirit an escape from Broodmother that is unaffected by her Incapacitating Bite.
Broodmother
* 
Great Cleave cleans up Spiderlings quicker than most spells, as it ignores their magic resistance.
* Sven is a natural 
Black King Bar carrier, protecting him from Silken Bola, Spawn Spiderlings and Orchid Malevolence.
* 
Warcry and 
God's Strength allow Sven to easily out-damage Broodmother.
Additional:
* Great Cleave can clear Spiderlings very quickly, and give Sven lot of gold.
* Warcry shields Sven and his allies against Broodmother and her Spiderlings.
Mirana
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, 
Outworld Destroyer, Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Broodmother
* 
Overwhelming Odds's damage stacks with each enemy unit in its radius. If this hits Broodmother and a large number of spiders it can deal significant amounts of damage.
* 
Moment of Courage has a high chance to proc if Broodmother and all of her spiders are attacking her.
* 
Duel can keep Broodmother in place long enough for Legion's team to kill her.
Additional:
* Overwhelming Odds is great at killing many stacked up spiderlings, thus giving Legion Commander a large buff.
* Duel is a reliable way to lock down Broodmother, preventing her from running into the treeline.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like 
Bane, 
Pudge, or Enigma are easy Sacred Arrow targets.
Broodmother
* 
Ion Shell zones out Broodmother in the laning phase, and can kill her spiderlings if used on one Spiderling in a group.
* 
Vacuum can pull Broodmother out of the treeline.
Additional:
* Ion Shell is a very powerful weapon against Broodmother's Spiderlings and makes her laning much harder.
Mirana
* Thirst detects Mirana or her ally at low health during 
Moonlight Shadow.
* Rupture deals high damage when Mirana uses Leap.
Additional:
* 
Rupture can quickly kill Mirana if she tries to Leap away.
* 
Thirst detects Mirana and her allies during Moonlight Shadow.
Broodmother
* 
Burrowstrike can be used as an escape or initiation against Broodmother.
* 
Sand Storm quickly kills any spiderlings caught inside if Sand King can manage to stun them.
Additional:
* Caustic Finale allows Sand King to easily kill Broodmother's Spiderlings throughout the game.
* Sand King can usually catch a split pushing Broodmother with 
Blink Dagger and Burrowstrike.
Broodmother
* 
Aftershock in combination with 
Enchant Totem prevents Broodmother from continuing to attack Earthshaker without being repeatedly stunned.
* 
Echo Slam is greatly amplified by Spiderlings, often instantly killing Broodmother, her swarm, and anyone else unfortunate enough to be nearby.
* Earthshaker's vast amount of stuns makes it difficult for Broodmother to continue attacking enemies (to continue lifestealing with Insatiable Hunger) without Black King Bar.
Additional:
* Echo Slam's damage potential increases phenomenally due to Broodmother's hordes of spiderlings and spiderites.
* Long ranged Fissures can hit Broodmother if she runs into the treeline at the edges of the map.
Broodmother
* Alchemist can easily farm Spiderlings with Acid Spray and Greevil's Greed.
* Alchemist's Chemical Rage nullifies Broodmother's 
Insatiable Hunger
Additional:
* 
Greevil's Greed makes Broodmother’s spiderlings far more valuable to Alchemist making it important that he does farm them as opposed to other heroes where the spider's bounties are negligible.
* 
Acid Spray makes it difficult to attack Alchemist in lane without losing some spiderlings to the damage over time, potentially giving him farm he wouldn't have otherwise.
Mirana
* 
Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* 
Shackleshot through tree with 
Focus Fire via Aghanim's Scepter combo can kill Mirana quickly, before using Leap or Moonlight Shadow.
Broodmother
* Your AoE abilities should make quick work of her spiderlings.
Broodmother
* 
Kraken Shell makes Tidehunter take nearly no damage from Spiderlings.
* 
Anchor Smash kills Spiderlings in one or two casts, should Broodmother try to swarm Tidehunter with them.
Broodmother
* Broodmother and her Spiderlings need to be very careful during the laning stage against Jakiro, as Jakiro can take down Broodmother's Spiderlings, preventing her from pushing as well as gaining a good amount of gold.
Mirana
* If Slark sees the Sacred Arrow before it hits him, he can use 
Dark Pact to remove it a moment later.
* 
Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter combo with 
Shadow Dance.
Broodmother
* While Broodmother can hide in the trees with 
Spin Web, Primal Beast's ability to trample trees down can give him an edge in catching her.
* Insatiable Hunger will not do much vs Primal Beast's onslaught of disables.
* While 
Silken Bola can slow Primal Beast down, it's not enough to stop Trample from doing more damage than Broodmother can do back.
* 
Spawn Spiderlings will be destroyed by Onslaught and Trample very easily.
Broodmother
* Spiderlings are a good source of farm for 
Necromastery and can be quickly killed with 
Shadowraze.
* Shadow Fiend is a natural Black King Bar carrier, protecting him from any of Broodmother's abilities.
* 
Requiem of Souls combined with 
Eul's Scepter of Divinity can potentially kill Broodmother before she gets a Black King Bar.
Broodmother
* 
Reactive Armor prevents Broodmother's spiderlings from being able to effectively harass Timbersaw in the lane.
* 
Timber Chain's high mobility makes Silken Bola's slow irrelevant, unless Broodmother already bought her Orchid.
* Silken Bola's miss chance doesnt affect Rizzrack that much because he does not rely on his autoattacks much.
* 
Lotus Orb items for Timbersaw make Silken Bola useless.
* Timbersaw's abilities can destroy any trees that Broodmother attempts to hide in and his AoE abilities can quickly clear her Spiderlings.
Additional:
* Spiderlings deal almost no damage against Reactive Armor. They also die quickly from Timbersaw's AoE abilities.
* Broodmother has no mobility ability except the movement speed buff from Spin Web, allowing Timbersaw to easily escape her Silken Bola with Timber Chain.
* Timbersaw's tree-cutting abilities make it difficult for Broodmother to hide, especially near the edges of the map.
Broodmother
* 
Death Pulse can easily wipe out Broodmother's spiderlings if they're too close while also offering Necrophos a source of regeneration for Broodmother's harass in lane.
* 
Ghost Shroud prevents Broodmother or her spiderlings from damaging Necrophos temporarily until Broodmother buys 
Nullifier or 
Revenant's Brooch.
* 
Heartstopper Aura will regenerate lost health and mana for every spiderling or spiderite Necrophos manages to kill.
Broodmother
* Illuminate wipes out Broodmother's spiders and prevents her from pushing the lane. It also gives vision to reveal where broodmother is hiding in the trees.
Mirana
* Mirana's Leap is ineffective if Lycan uses 
Shapeshift. It also allows him to dodge Sacred Arrow.
Broodmother
* Tiny can quickly clear Spiderlings with his active abilities and cleave.
Broodmother
* 
Breathe Fire will clear Broodmother's spiderites while significantly damaging her spiderlings and decreasing their damage output.
* 
Dragon Blood's added armor and regen mitigates the damage done by Broodmother and her spiders.
* 
Elder Dragon Form at level 2 and above applies splash damage to Dragon Knight's auto attacks.
Broodmother
* Quill Spray destroys spiderlings, and hits Broodmother even when she's regenerating in her webs. This makes Bristleback one of her hardest counters in lane.
Additional:
* 
Bristleback reduces most of Broodmother's and her spiderlings' damage.
* 
Quill Spray will hit any spiders in its proximity, hindering Broodmother's fighting and farming capabilities.
Broodmother
* 
Swashbuckle can be used for Pangolier to escape or kill Broodmother's spiders. Combined with 
Lucky Shot Pangolier can potentially disarm Broodmother preventing her from lifestealing off enemies.
* 
Shield Crash can be used for wave clear to deal with Broodmother's spiders.
* 
Rolling Thunder can be used as an escape or a means of initiating on Broodmother.
Additional:
* Swashbuckle and Shield Crash quickly destroys Broodmother's spiderlings and spiderites.
* Lucky Shot's disarm is very valuable when dealing with a Broodmother during her Insatiable Hunger.
Mirana
* 
Doom completely takes Mirana out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Broodmother
* Broodmother, Nature's Prophet, Phantom Lancer by their nature offer very good target for Splinter Blast and Winter's Curse.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Broodmother
* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.
Mirana
* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: 
Bounty Hunter, Mirana, Riki
Broodmother
* Charge of Darkness provides shared vision over its target, keeping track of heroes who rely on invisibility, mobility, or illusions: Riki, Broodmother, Phantom Lancer
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to 
Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, 
Nyx Assassin, Mirana, Bounty Hunter, 
Templar Assassin, Riki, 
Spirit Breaker, Anti-Mage, 
Tusk, 
Ursa, Nature's Prophet, Enigma, 
Void Spirit, 
Magnus etc.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes who rely on invisibility, such as Bounty Hunter, 
Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, 
Zeus and 
Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.
Broodmother
* Heroes who cannot fight back during Arena of Blood in the early and mid game: 
Abaddon, Anti-Mage, Broodmother, 
Luna, 
Sniper, 
Troll Warlord, 
Weaver, Clinkz.
Broodmother
* Heroes with area of effect abilities that increase in power based on the number of units struck: 
Earthshaker, Legion Commander, 
Grimstroke.
Additional:
* Stroke of Fate can deal heavy damage to Broodmother and her spiders, and with enough spiders it can kill her instantly.
* Phantom's Embrace provides vision on Broodmother when she's fleeing into the trees.
Broodmother
* Heroes reliant on illusions or summons: Broodmother, 
Chaos Knight, 
Naga Siren.
Mirana
* The long silence of 
Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With 
Dark Ascension and 
Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Broodmother
* Heroes with illusions and summons can manfight Night Stalker: 
Terrorblade, 
Beastmaster, Broodmother.
Broodmother
* Void Spirit's AoE damage can make short work of Broodmother's spiderlings
* Even if she is within the range of her spiderwebs from Spin Web Broodmother cannot escape Void Spirit's mobility.
* However, Spinner's Snare from Aghanim's Scepter can be very hazardous for Void Spirit, as it allows Broodmother to create invisible lines on her webs from Spin Web that will root Void Spirit, deal damage over time to him and reveal him if he unwittingly steps on them, disrupting Void Spirit's ganking or escaping attempts with 
Dissimilate and 
Astral Step while also alerting Broodmother on his attempts to ambush her and her allies.
Additional:
* Void Spirit's AoE damage can make short work of Broodmother's spiderlings
* Even if she is within the range of her spiderwebs from Spin Web Broodmother cannot escape Void Spirit's mobility.
* However, Spinner's Snare from Aghanim's Scepter can be very hazardous for Void Spirit, as it allows Broodmother to create invisible lines on her webs from Spin Web that will root Void Spirit, deal damage over time to him and reveal him if he unwittingly steps on them, disrupting Void Spirit's ganking or escaping attempts with Dissimilate and Astral Step while also alerting Broodmother on his attempts to ambush her and her allies.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Mirana
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from 
Eclipse with Moonlight Shadow, smart Luna can buy 
Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Mirana
* A couple of long-range heroes with excellent laning like Mirana, 
Lina, 
Necrophos, 
Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Mirana
* Mirana can use Leap to jump right next to Drow Ranger or can approach her while under cover of the invisibility granted by Moonlight Shadow, which cancels the bonus granted to Drow Ranger by 
Marksmanship.
* Her low health makes her easy to burst down with Mirana's spells, especially with Aghanim's Scepter.
* Mirana can dodge 
Gust with good reaction time, or Leap away if Drow tries to slow her without Gust.
Broodmother
* Drow Ranger's lack of mobility and area-of-effect abilities makes her easy prey for Broodmother and her Spiderlings.
Mirana
* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: 
Lifestealer, 
Doom, Mirana, Clinkz.
Broodmother
* Chen has no area-of-effect spells to deal with Broodmother's spiderlings and must rely on his creeps to take care of them.
* Spawn Spiderlings can kill Chen's creeps and spawn spiderlings in their place.
* Spin Web allows Broodmother to disrupt Chen's jungling.
* Silken Bola will cause Chen and his creeps's attack to miss more often while also making them more vulnerable to magical damage, especially if Broodmother picks 400 AoE Silken Bola talent.
* Broodmother is a natural 
Bloodthorn wielder, which will allow her to prevent Chen from trying to save himself with 
Hand of God while also making him more vulnerable to damage, and when combined with Insatiable Hunger, it will spell a quick and certain death for Chen. Bloodthorn's passive ability will also reduce any spell damage Chen tries to inflict with his creeps.
* Spinner's Snare from Aghanim's Scepter allows Broodmother to create invisible lines on her webs from Spin Web that will root Chen and his creeps, deal damage over time to them and reveal them if they unwittingly steps on them, disrupting Chen's jungling even more while also alerting Broodmother on their attempts to ambush her and her allies.
Additional:
* Chen has no area-of-effect spells to deal with Broodmother's spiderlings and must rely on his creeps to take care of them.
* Spawn Spiderlings can kill Chen's creeps and spawn spiderlings in their place.
* Spin Web allows Broodmother to disrupt Chen's jungling.
* Silken Bola will cause Chen and his creeps's attack to miss more often while also making them more vulnerable to magical damage, especially if Broodmother picks 400 AoE Silken Bola talent.
* Broodmother is a natural Bloodthorn wielder, which will allow her to prevent Chen from trying to save himself with Hand of God while also making him more vulnerable to damage, and when combined with Insatiable Hunger, it will spell a quick and certain death for Chen. Bloodthorn's passive ability will also reduce any spell damage Chen tries to inflict with his creeps.
* Spinner's Snare from Aghanim's Scepter allows Broodmother to create invisible lines on her webs from Spin Web that will root Chen and his creeps, deal damage over time to them and reveal them if they unwittingly steps on them, disrupting Chen's jungling even more while also alerting Broodmother on their attempts to ambush her and her allies.
Mirana
* Techies spends lots of time standing still planting stacks of 
Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use 
Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.
Broodmother
* Heroes with summons like Broodmother, Enigma, Nature's Prophet; or illusions, like Naga Siren, Terrorblade are effective at keeping the choke points and rune spawns safe from Proximity Mines.
Mirana
* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* 
Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
Broodmother
* Heroes with plenty of summons, such as Broodmother or Nature's Prophet can have their minions soak up most of your Paralyzing Cask.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Broodmother
* Broodmother can kill Enigma's Eidolons with Spawn Spiderlings, and spawn her spiderlings in their place. But remember that Enigma can do the same to Broodmother's spiderlings with 
Demonic Conversion and 
Midnight Pulse.
* Without the protection from Black King Bar, Broodmother can cancel Enigma's 
Black Hole with Bloodthorn and make him more vulnerable to damage. Broodmother can also buy 
Abyssal Blade to cancel Enigma's Black Hole even through Black King Bar.
* Silken Bola causes Enigma's attacks to miss a lot and renders him more vulnerable to magical damage. And if Broodmother takes 400 AoE Silken Bola, then she will be able to use to cause Enigma's Eidolons to miss their attacks as well. In addition, Enigma does not like to buy items to provide him true strike such as Bloodthorn, 
Monkey King Bar, 
Witch Blade and it's upgrade Revenant's Brooch.
* If Broodmother is lucky enough to survive being trapped in Black Hole, she will be able to recover her lost health with Insatiable Hunger.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Enigma, deal damage over time to Enigma and reveal Enigma if he unwittingly steps on them, disrupting his attempts to initiate with Black Hole, prevent him from using Blink Dagger, while also alerting Broodmother on his attempts to ambush her and her allies.
Additional:
* Broodmother can kill Enigma's Eidolons with Spawn Spiderlings, and spawn her spiderlings in their place. And Enigma can't use 
Demonic Summoning to instantly kill spiderlings at once.
* Without the protection from Black King Bar, Broodmother can cancel Enigma's Black Hole with Bloodthorn and make him more vulnerable to damage. Broodmother can also buy Abyssal Blade to cancel Enigma's Black Hole even through Black King Bar.
* Silken Bola causes Enigma's attacks to miss a lot and renders him more vulnerable to magical damage. And if Broodmother takes 400 AoE Silken Bola, then she will be able to use to cause Enigma's Eidolons to miss their attacks as well. In addition, Enigma does not like to buy items to provide him true strike such as Bloodthorn, Monkey King Bar, Witch Blade and it's upgrade Revenant's Brooch.
* If Broodmother is lucky enough to survive being trapped in Black Hole, she will be able to recover her lost health with Insatiable Hunger.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Enigma, deal damage over time to Enigma and reveal Enigma if he unwittingly steps on them, disrupting his attempts to initiate with Black Hole, prevent him from using Blink Dagger, while also alerting Broodmother on his attempts to ambush her and her allies.
Mirana
* Mirana can disturb Shadow Shaman's channeling even if he is under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with 
Ethereal Blade the bullying towards Shadow Shaman can continue for the whole match.
Broodmother
* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: 
Shadow Shaman, 
Visage, 
Dazzle, 
Rubick, 
Lich.
Mirana
* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys 
Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.
Broodmother
* Broodmother's 
Incapacitating Bite can make Nuerta's miss her attacks from 
Gunslinger more often until she buys items that require 
Javelin.
* Broodmother can still use Spawn Spiderlings to hurt Muerta while she has 
Pierce The Veil active as it deals magical damage and has a low cooldown.
* Broodmother can buy Revenant's Brooch to attack Muerta even through Pierce The Veil with Insatiable Hunger.
* Spin Web's movement speed gain for Broodmother makes it difficult for her to hit Broodmother with 
Dead Shot and keep her trapped in 
The Calling.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare which allows her to create up to 5 invisible web lines on her webs from Spin Web that can deal magical damage over time to Muerta, root her and reveal her if she unwittingly steps on them, foiling both, her escaping and ganking attempts while allowing Broodmother to alert her allies about her attempting to ambush them.
Mirana
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, 
Faceless Void, Magnus
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of 
Chen or 
Enchantress.
Broodmother
* Enchantress's lack of area-of-effect abilities allows Broodmother to swarm her with Spiderlings.
* Spawn Spiderlings can kill enchanted creeps and create Spiderlings in their place.
* However, bear in mind that 
Untouchable makes it harder for Broodmother to actually hit Enchantress, even if Broodmother is spell immune. And Broodmother's only way to counter this is either by buying 
Silver Edge, buying items that deal high magical damage like 
Dagon, or by buying items that give high attack speed like 
Moon Shard.
Additional:
* Enchantress can be easily overwhelmed with Broodmother's spiderlings from Spawn Spiderlings and Enchantress can only control one of them with 
Enchant and she has no good waveclear (Spawn Spiderlings can also kill creeps controlled with Enchant).
* However, Untouchable's attack speed reduction can make it difficult for Broodmother to kill Enchantress even with any form of spell immunity.
Broodmother
* Broodmother can kill Invoker easily in the early game with her Spawn Spiderlings and her spiderlings.
* Broodmother is both an Orchid Malevolence and a Nullifier carrier. As she can farm it early, she can kill Invoker easily.
Broodmother
* Sniper is completely helpless against Broodmother's abilities, and can be seriously damaged by Spiderlings in lane, especially when 
Shrapnel is on cooldown.
Mirana
* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If 
Frostbite has already been used, Mirana can Leap away even when slowed by 
Crystal Nova or 
Freezing Field.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Counterspell does not protect Anti-Mage from Sacred Arrow.
* Moonlight Shadow can help her allies avoid Mana Break and Mana Void.
* Blink's cooldown isn't short enough to escape from Leap, especially when she has the extra charge from 
Aghanim's Shard.
Additional:
* Combo items for Mirana 
Rod of Atos can upgrade to 
Gleipnir and Sacred Arrow before and during Anti-Mage build item 
Manta Style cooldown can easy penetrates Counterspell broken.
* Charge for Leap can Mirana easily faster escaping.
* Moonlight Shadow it can disappear anytime and Anti-Mage can not fight.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Broodmother
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Phantom Assassin, deal damage over time to Phantom Assassin and reveal Phantom Assassin if she unwittingly steps on them, disrupting her attempts to initiate or escape with with 
Phantom Strike while also alerting Broodmother on her attempts to ambush her and her allies.
Additional:
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Phantom Assassin, deal damage over time to Phantom Assassin and reveal Phantom Assassin if she unwittingly steps on them, disrupting her attempts to initiate or escape with with Phantom Strike while also alerting Broodmother on her attempts to ambush her and her allies.
Broodmother
* Viper's lack of escape and durability means he can be ran over in a laning stage by Spawn Spiderlings.
* Broodmother can bring Viper down quickly with Insatiable Hunger activated.
Mirana
* Low-health, normally mobile carries who rely entirely on raw attack damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, 
Drow Ranger, Faceless Void, 
Gyrocopter, 
Juggernaut, 
Meepo, Mirana, 
Monkey King, 
Morphling, Phantom Assassin, Phantom Lancer, Riki, 
Shadow Fiend, 
Slark, Sniper, Terrorblade, Troll Warlord, Weaver.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Broodmother
* Insatiable Hunger's attack damage amplification can reduce the effectiveness of 
Enfeeble, and the Enfeeble will not weaken the magical damage output from Silken Bola, Spawn Spiderlings and Spinner's Snare from Aghanim's Scepter, though it will still reduce their cast range.
* Bane's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to cancel 
Fiend's Grip, and completely shut Bane down.
Additional:
* Insatiable Hunger's attack damage amplification can reduce the effectiveness of Enfeeble, and the Enfeeble will not weaken the magical damage output from Silken Bola, Spawn Spiderlings and Spinner's Snare from Aghanim's Scepter, though it will still reduce their cast range.
* Bane's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to cancel Fiend's Grip, and completely shut Bane down.
Broodmother
* Broodmother can easily clear Wraith King's skeletons with Spawn Spiderlings and summon spiderlings in their place.
* With 
Diffusal Blade, Broodmother can prevent Wraith King from reincarnating unless Wraith King has his Aghanim's Shard.
Broodmother
* Webbed areas can be used to hit and run, covering distance hastily weakening her on the way and initiating ganks.
* Even though Medusa can hunt down Spiderlings easily when given enough range, Silken Bola will cause her attacks to miss and get her swarmed in no time.
* Medusa usually does not build a Black King Bar to benefit from 
Mana Shield fully while Broodmother can fit a Diffusal Blade to burn away all of Medusa's mana.
Additional:
* Spin Web will allow Broodmother to pick her own fights and sometimes slip away to ambush Medusa.
* Though Medusa's Split Shot and Mystic Snake can help Medusa deal with Broodmother's spiderlings, Broodmother will create too much of them for her to handle, allowing her to outnumber Medusa's targets from Split Shot and shield her team in process.
Broodmother
* Heroes who can summon illusions and summons because Terrorblade has no abilities to deal with multiple enemies at once outside Reflection: Shadow Shaman, Naga Siren, Broodmother, 
Lycan, Enigma, Chaos Knight, Phantom Lancer, Shadow Demon, 
Dark Seer, Nature's Prophet, 
Invoker, Morphling, Visage, Grimstroke with Aghanim's Scepter.
Broodmother
* Heroes with blind of some sort can be a bad choice for Monkey King to go on: Broodmother, Riki, 
Keeper of the Light.
Mirana
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: 
Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, 
Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Broodmother
* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.
Broodmother
* Illusion-based and multi-unit heroes can take advantage of Chaos Knight's lack of area damage: Naga Siren, Phantom Lancer, Broodmother
Broodmother
* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates difficult targets to hook.
* Sacred Arrow can be used to cancel Dismember from long distances.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Broodmother
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, 
Warlock, 
Wraith King.
Broodmother
* Clockwerk lacks burst damage, and that makes him vulnerable to heroes who can recover themselves and turn the fight around to their advantage after Clockwerk finishes his initiation. Additionally, Clockwerk hates buying Dagon and Ethereal Blade, which are the only itmes that can help him deal with heroes who can recover themselves and turn the fight around to their advantage: Faceless Void, Terrorblade, Ursa, Weaver, Broodmother, Slark, Abaddon, Wraith King, Lifestealer.
Mirana
* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.
Broodmother
* Support heroes with low mobility can be slowed further by Incapacitating Bite, and swarmed by Spiderlings for an easy kill: Shadow Shaman, Visage, Dazzle, Rubick, Lich.
Additional:
* Chain Frost can bounce to the Spiderlings that Broodmother spawns.
Broodmother
* Heroes with summons: Lycan, Broodmother, Visage, Nature's Prophet, Warlock.
Broodmother
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, 
Dawnbreaker's 
Solar Guardian, 
Axe's Berserker's Call, 
Mars's 
Arena of Blood, 
Jakiro's 
Macropyre, 
Dual Breath and 
Ice Path, Naga Siren's 
Song of the Siren, 
Razor's 
Eye of the Storm and 
Plasma Field, Lina's 
Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, 
Elder Titan's 
Earth Splitter and Echo Stomp, 
Alchemist's 
Unstable Concoction and Acid Spray, Queen of Pain's 
Sonic Wave, Dark Seer's 
Wall of Replica and Vacuum, 
Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from Aghanim's Shard, 
Bloodseeker's 
Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, 
Batrider's Aghanim's Scepter upgraded 
Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, 
Ancient Apparition's 
Ice Blast, 
Sand King's 
Epicenter, Sand Storm and Burrowstrike, Gyrocopter's 
Call Down, 
Ember Spirit's Sleight of Fist, Death Prophet's 
Exorcism and 
Silence, Monkey King's 
Wukong's Command, 
Crystal Maiden's Freezing Field, 
Muerta's The Calling, 
Medusa's 
Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, 
Pangolier's Swashbuckle, Grimstroke's 
Soulbind, 
Ink Swell and 
Stroke of Fate, Earthshaker's Echo Slam and 
Fissure, 
Puck's Dream Coil and Waning Rift, 
Winter Wyvern's 
Winter's Curse, Magnus's 
Reverse Polarity.
Broodmother
* Heroes with very little to no area-of-effect abilities will struggle greatly against Broodmother: Sniper, Phantom Assassin, Nyx Assassin, Bane, Visage, Bounty Hunter.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Broodmother
* 
Sprout cannot protect Nature's Prophet if Broodmother puts down a web.
* Nature's Prophet's low mobility means he is defenseless against Silken Bola.
* Spiderlings can absorb much of the damage from 
Wrath of Nature.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Nature's Prophet, deal damage over time to Nature's Prophet and reveal Nature's Prophet if he unwittingly steps on them, disrupting his attempts to perform surprise attacks on Broodmother's allies with Silver Edge and also prevent him from using Silver Edge to esacape, while also alerting Broodmother on his attempts to ambush her and her allies.
Additional:
* Broodmother can destroy Nature's Prophet's Treants with Spawn Spiderlings and summon spiderlings in their place.
* Broodmother loves buying Orchid Malevolence, which can prevent Nature's Prophet from escaping with Sprout and Teleportation.
Mirana
* Heroes with silences and hard stuns such as Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Broodmother
* Broodmother relies less on abilities and more on right-clicks.
* Spiderlings can overwhelm Silencer, who has mediocre armor and no escape tool.
Mirana
* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like Storm Spirit, Mirana, Anti-Mage and others won't be able to do much if they're caught.
Broodmother
* Spiderlings melt away 
Living Armor almost instantly.
* The vision from 
Eyes In The Forest may prove dangerous for Broodmother, however.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Mirana
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or 
Leshrac's 
Split Earth, or combos like 
Kunkka's 
X Marks the Spot into 
Torrent.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Broodmother
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: Phantom Assassin, Nyx Assassin, Mirana, Bounty Hunter, Templar Assassin, Riki, Spirit Breaker, Anti-Mage, Tusk, Ursa, Nature's Prophet, Enigma, Void Spirit, Magnus etc.
Broodmother
* Ice Blast prevents Insatiable Hunger lifesteal, Spin Web regeneration and quickly kills spiderlings.
Mirana
* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.
Broodmother
* X Marks the Spot prevents Broodmother from escaping.
* 
Tidebringer can clear Broodmother's spiders if they get in range.
Additional:
* Kunkka's entire kit is great for taking out multiple units at once.
* Tidebringer's cleave will split through a wave of spiderlings.
* X Marks the Spot is great for dragging Broodmother back out of her web for Kunkka's team to set up on her.
* Torrent and Ghostship will demolish any spiderlings within the radius.
Mirana
* Leap allows Mirana to easily escape Torrent and Ghostship.
Mirana
* 
Track detects Mirana and her allies during Moonlight Shadow.
Broodmother
* Bounty Hunter's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to stop Bounty Hunter from escaping with Shadow Walk.
Additional:
* Like with Bane, Bounty Hunter's single-targeted arsenal of abilities make him an easy target for Broodmother and her Spiderlings.
* Broodmother often buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to stop Bounty Hunter from escaping with 
Shadow Walk.
* Spinner's Snare from Aghanim's Scepter allows Broodmother to create invisible lines on her webs from Spin Web that will root Bounty Hunter, deal damage over time to him and reveal him if he unwittingly steps on them, disrupting Bounty Hunter's ganking attempts with Shadow Walk while also alerting Broodmother on his attempts to ambush her and her allies.
Mirana
* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Additional:
* 
Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place 
Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
Broodmother
* None of Arc Warden's abilities are very effective against Broodmother and her spiderlings.
* A good Broodmother looks to end the match early while Arc Warden, a very item reliant hero, thrives in longer matches.
* Arc Warden has no innate disables to stop Broodmother from lifestealing with Insatiable Hunger and shredding through his relatively lower armor.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Broodmother
* Oracle cannot easily deal with swarms of units, making him weak against heroes like Phantom Lancer or Broodmother.
Mirana
*
Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
Moonlight Shadow.
Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and 
Light Strike Array can disable Mirana if she tries to Leap away.
Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with
Additional:
*
*
Broodmother
*
Light Strike Array in combination with 
Dragon Slave can easily clear Broodmother's spiders.
Laguna Blade offers extensive damage that can kill Broodmother early on or before she is able to use Insatiable Hunger in attempts to salvage a fight.
*