Mirana
* 
Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place 
Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
Additional:
* Arc Warden can use his summons to prevent 
Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Mirana
* Abaddon can remove Sacred Arrow's stun from his teammates with 
Aphotic Shield, or remove it from himself with 
Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's 
Aghanim's Scepter combo.
Additional:
* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Leshrac
* Nyx Assassin's 
Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* 
Mind Flare deals high damage due to Leshrac's high intelligence gain.
* 
Vendetta burns a large amount of Leshrac's essential mana pool.
Leshrac
* Leshrac's high magic damage is ignored by 
Rage.
* Lifestealer can get in Leshrac's face with Rage and mitigate any other damage taken by Leshrac with 
Open Wounds.
Leshrac
* Leshrac needs to be close to target in order to do damage, Pugna can outrun Leshrac with ease due to his superior movement speed.
* 
Split Earth can also be hard to land on Pugna for the same reason.
* Leshrac uses huge amounts of mana to do damage, Nether Ward forces him to either not contribute in a fight or kill himself in the process.
Additional:
* 
Nether Ward punishes Leshrac's constant mana usage from spamming spells.
* Leshrac needs to be in the thick of the fight to deal damage, and so cannot escape from 
Nether Blast nor 
Life Drain easily.
Mirana
* 
Track detects Mirana and her allies during Moonlight Shadow.
Mirana
* Thirst detects Mirana or her ally at low health during 
Moonlight Shadow.
* Rupture deals high damage when Mirana uses 
Leap.
Additional:
* 
Rupture can quickly kill Mirana if she tries to Leap away.
* 
Thirst detects Mirana and her allies during Moonlight Shadow.
Mirana
* 
Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and 
Light Strike Array can disable Mirana if she tries to Leap away.
* 
Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.
Additional:
* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Mirana
* Puck can initiate on Mirana with 
Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in 
Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with 
Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid 
Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.
Mirana
* Heroes with spells that negate invisibility such as 
Bounty Hunter, 
Zeus and 
Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like 
Storm Spirit, 
Mirana, 
Anti-Mage and others won't be able to do much if they're caught.
Leshrac
* Heroes with spell immunity: 
Juggernaut, 
Pangolier, 
Huskar.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, 
Queen of Pain, Storm Spirit, 
Riki.
Mirana
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, 
Outworld Destroyer, 
Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Heroes with silences and hard stuns such as 
Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Mirana
* Heroes who rely on invisibility, such as Bounty Hunter, 
Clinkz, Mirana, 
Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Leshrac
* Heroes who rely on burst damage with magical damage will struggle to kill Primal Beast: 
Spirit Breaker, 
Gyrocopter, 
Leshrac
Leshrac
* Heroes with spell immunity: Juggernaut, Pangolier, Huskar.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Leshrac
* Heroes with long cast animations can be continuously interrupted by Battery Assault: 
Centaur Warrunner, 
Jakiro, Leshrac, 
Naga Siren, 
Underlord.
Additional:
* Clockwerk naturally builds 
Blade Mail, reflecting Leshrac's high magic damage output back at him.
* 
Power Cogs will prevent Leshrac from reaching Clockwerk's team and dealing large AOE damage to them.
* Power Cogs will also keep Leshrac close, wasting his Diabolic Edict on just Clockwerk.
* 
Battery Assault interrupts Leshrac's long cast times of Split Earth and Lightning Storm.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Leshrac
* Heroes with spell immunity: Juggernaut, Pangolier, Huskar.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Additional:
* All abilities from Mirana can shut down with 
Doom and Mirana can not escape with Leap since Doom activated.
* Doom also catch Mirana disabled used combo items Doom from ugrade Aghanim's Scepter and 
Blink Dagger or 
Overwhelming Blink make Mirana can not move escaping notably Leap and Moonlight Shadow.
Mirana
* The long silence of 
Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With 
Dark Ascension and 
Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Leshrac
* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, 
Pugna, 
Death Prophet.
Mirana
* Mirana's Leap is ineffective if Lycan uses 
Shapeshift. It also allows him to dodge Sacred Arrow.
Leshrac
* Heroes who summon multiple units that are not spell immune. 
Nature's Prophet,
Lycan,
Beastmaster
Mirana
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from 
Eclipse with Moonlight Shadow, smart Luna can buy 
Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Mirana
* A couple of long-range heroes with excellent laning like Mirana, 
Lina, 
Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Mirana
* If Slark sees the Sacred Arrow before it hits him, he can use 
Dark Pact to remove it a moment later.
* 
Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter combo with 
Shadow Dance.
Leshrac
* Heroes with AoE abilities will hit Slark in Shadow Dance: Lina, Jakiro, Underlord, Leshrac, 
Dark Seer, 
Earthshaker, 
Timbersaw, 
Crystal Maiden.
Mirana
* 
Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* 
Shackleshot through tree with 
Focus Fire via Aghanim's Scepter combo can kill Mirana quickly, before using Leap or Moonlight Shadow.
Leshrac
* Since Windranger is bad against magical damage, heroes with continuous magical damage or magical nukes can blast her: Zeus, 
Tinker, Leshrac, 
Viper, 
Skywrath Mage, Lion, Lina, 
Venomancer.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Leshrac
* Anti-Mage can withstand magical burst damage much better than other carries, making him effective against nukers: 
Lich, Necrophos, Oracle, and Leshrac.
Additional:
* 
Counterspell severely reduces Leshrac's magical damage.Counterspell also impacted reflect Lightning Storm and send back to Leshrac's also affected from movement speed.
* Leshrac already burns through his own mana with Pulse Nova, 
Mana Break will burn through even more.
* Leshrac's high mana pool will increase the amount of damage 
Mana Void does to him when his mana is low.
Mirana
* Counterspell does not protect Anti-Mage from Sacred Arrow.
* Moonlight Shadow can help her allies avoid Mana Break and Mana Void.
* Blink's cooldown isn't short enough to escape from Leap, especially when she has the extra charge from 
Aghanim's Shard.
Additional:
* Combo items for Mirana 
Rod of Atos can upgrade to 
Gleipnir and Sacred Arrow before and during Anti-Mage build item 
Manta Style cooldown can easy penetrates Counterspell broken.
* Charge for Leap can Mirana easily faster escaping.
* Moonlight Shadow it can disappear anytime and Anti-Mage can not fight.
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of 
Chen or 
Enchantress.
Leshrac
* Leshrac's AoE abilities make quick work of Chen's creep army.
Mirana
* Heroes that cannot move in fights such as a 
Dueling Legion Commander or anyone channeling a spell like 
Bane, 
Pudge, or 
Enigma are easy Sacred Arrow targets.
Leshrac
* Heroes who can clear the waves of Enigma's Eidolons: Lina, 
Luna, 
Dawnbreaker, Jakiro, 
Shadow Shaman, Death Prophet, 
Keeper of the Light, 
Invoker, Leshrac, 
Puck.
Mirana
* Techies spends lots of time standing still planting stacks of 
Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use 
Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.
Mirana
* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys 
Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and 
Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.
Mirana
* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If 
Frostbite has already been used, Mirana can Leap away even when slowed by 
Crystal Nova or 
Freezing Field.
Leshrac
* 
Pulse Nova can easily burn Templar Assassin's 
Refraction charges quickly, and can also hit her with her 
Meld.
Mirana
* Mirana can use Leap to jump right next to Drow Ranger or can approach her while under cover of the invisibility granted by Moonlight Shadow, which cancels the bonus granted to Drow Ranger by 
Marksmanship.
* Her low health makes her easy to burst down with Mirana's spells, especially with Aghanim's Scepter.
* Mirana can dodge 
Gust with good reaction time, or Leap away if Drow tries to slow her without Gust.
Mirana
* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.
Leshrac
* All of Leshrac's abilities, especially Pulse Nova, can easily deal with Naga Siren's illusions.
* Aghanim's Scepter gives Leshrac access to 
Nihilism ability, that allows him to turn himself along with Naga Siren and her illusions to turn ethereal. And to make things worse, Nihilism can slow Naga Siren and her illusions, make them more vulnerable to magical damage and unable to fight back while Leshrac moves faster and does not take increased magical damage for it's duration.
Mirana
* Mirana can disturb Shadow Shaman's channeling even if he is under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying towards Shadow Shaman can continue for the whole match.
Mirana
* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* 
Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
Leshrac
* Lightning Storm will usually hit both Io and his 
Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.
Additional:
* Io is a hero who needs to be close to it's tethered target to make it effective, and that's where Leshrac gets the advantage thanks to many of his area-of-effect abilities.
* 
Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* 
Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to both, Io and its tethered target.
Mirana
* Leap allows Mirana to easily escape Torrent and Ghostship.
Leshrac
* Diabolic Edict and Pulse Nova hit all units around Leshrac, making it very easy for him to kill the 
Summon Familiars.
* Diabolic Edict and Pulse Nova also deal many instances of damage, nullifying 
Gravekeeper's Cloak.
* Split Earth and Lightning Storm makes it difficult for 
Visage to kite Leshrac, even while under the effects of 
Grave Chill.
Leshrac
* As Terrorblade's damage output comes mainly from direct attacks, he will struggle greatly against heroes who have abilities that give evasion, trigger on attack or which can disarm an enemy hero: Centaur Warrunner, 
Hoodwink, Huskar, Invoker, Leshrac with Nihilism from Aghanim's Scepter, 
Lifestealer with Aghanim's Scepter upgraded 
Infest, Pangolier, 
Phantom Assassin, Pugna, 
Techies, 
Windranger etc.
Leshrac
* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain
Leshrac
* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,Beastmaster
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Mirana
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or Leshrac's Split Earth, or combos like 
Kunkka's 
X Marks the Spot into 
Torrent.
Leshrac
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or Leshrac's Split Earth, or combos like Kunkka's X Marks the Spot into Torrent.
Leshrac
* Heroes with wide AoE abilities will reveal Monkey King through Mischief: Necrophos, 
Phoenix, 
Alchemist, Earthshaker, 
Razor, Tinker, Leshrac, Queen of Pain
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates difficult targets to hook.
* Sacred Arrow can be used to cancel Dismember from long distances.
Mirana
* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.
Mirana
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: 
Arc Warden, Chen, Clinkz, 
Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and 
Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, 
Phantom Lancer, Nature's Prophet.
Leshrac
* Diabolic Edict and Pulse Nova will tear apart any illusions spawned from 
Disruption
* Split Earth can punish improper usage of Disruption.
* Leshrac does not have any buffs that can be removed by 
Demonic Purge.
Additional:
* Pulse Nova makes quick work of any illusions with amplified damage, and deals damage even if Leshrac is in Disruption.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Split Earth for the enemy.
* Disruption does not stop Diabolic Edict and Pulse Nova once they start pulsing, and even worse it provides a safe shelter for Leshrac to keep pumping up his powerful AoE damage onto the battlefield.
* Shadow Demon doesn't have the burst damage to take Leshrac out of the fight quickly, although Demonic Purge can help his allies kill a squishy Leshrac.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Leshrac
* Leshrac's AoE abilities destroy Phantom Lancer's illusions.
* Diabolic Edict and Pulse Nova require no targeting, thus hitting Phantom Lancer whenever he's nearby.
Additional:
* Leshrac can easily clear Phantom Lancer's illusions with his huge area of effect damage.
Mirana
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, 
Faceless Void, 
Magnus
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or Enchantress.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Mirana
* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki
Leshrac
* Heroes who can continue dealing damage even while being stunned: Luna, Razor, 
Axe, 
Bristleback, Leshrac, Death Prophet.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Leshrac
* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,Beastmaster
Mirana
* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, 
Meepo, Mirana, 
Monkey King, 
Morphling, Phantom Assassin, Phantom Lancer, Riki, 
Shadow Fiend, 
Slark, Sniper, 
Terrorblade, 
Troll Warlord, 
Weaver.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Mirana
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from 
Spawn Spiderlings, which in combination with the huge speed provided by 
Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys 
Orchid Malevolence and it's upgrade 
Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
Leshrac
* Your AoE abilities should make quick work of her spiderlings.
Mirana
* 
Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by 
Poof and 
Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Leshrac
* Pulse Nova deals an insane amount of damage in an area around him, which can quickly wear down Meepo clones.
* Leshrac can catch multiple Meepos in Split Earth and follow up with the rest of his area damage spells making Meepo unable to get close to Leshrac.
* Diabolic Edict is a strong ability that can wear down a lone Meepo clone quickly.
Mirana
* Heroes that can protect or dispel stunned allies such as
Legion Commander, 
Outworld Destroyer, 
Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Leshrac
* Oracle's
Fate's Edict will protect an ally from Leshrac's nuking damage.
False Promise can dispel Leshrac's stun and slow from his abilities, allowing an ally to escape.
Fortune's End can stop Leshrac from chasing opponents or running away.
* Oracle's
*