* Thirst detects Mirana or her ally at low health during Moonlight Shadow.
* Rupture deals high damage when Mirana uses Leap.
Additional:
* Rupture can quickly kill Mirana if she tries to Leap away.
* Thirst detects Mirana and her allies during Moonlight Shadow.

* Rupture completely negates Lycan's high mobility.
* All of Lycan's summons are good sources of healing with Bloodrage.
Additional:
* Rupture completely negates Lycan's high mobility.
* All of Lycan's summons are good sources of healing with Bloodrage.

* If Slark sees the Sacred Arrow before it hits him, he can use Dark Pact to remove it a moment later.
* Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter​ combo with Shadow Dance.

* Lycan cannot escape from a Pounce even if he uses Shapeshift, and has no disabling abilities to stop Slark.

* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like Storm Spirit, Mirana, Anti-Mage and others won't be able to do much if they're caught.

* Treant Protector grants protection against his attacks with Living Armor and his ultimate, Overgrowth is a massive AoE disarm and root that pierces spell immunity, causing trouble to Lycan. You will find yourself in need of an ally's dispel or forced to pop Black King Bar for its dispel.

Additional:
* Lycan has no kind of teleport, being only able to walk, and heavily relies on his attacks. As Overgrowth roots and disarms the targets, Lycan can't do much in an overgrowth field.

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Faceless Void can lock Lycan down with his Chronosphere pinning him down as long as his ultimate is up.

* Guardian Angel completely negates all of Lycan's damage since Lycan mainly deals physical damage.
* Purification can also be a problem for Lycan, as Purification deals damage around the target, which poses a problem for him and his summons.

* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.

* Brewmaster can waste a large portion of Lycan's ultimate by putting him in Cyclone.
* Lycan has no way to stop Brewmaster from using Primal Split by himself.
* Lycan's team often tries to push towers as a group, and Brewmaster excels at winning teamfights while trying to defend a tower.

* Lycan is a hero focused entirely on single target physical damage and lacks disables or AoE damage. Due to this, he has difficulties dealing with illusions or Naga Siren's Ensnare.

* Track detects Mirana and her allies during Moonlight Shadow.

* A well landed Fissure can potentially take Lycan out of the fight for several seconds, who heavily relies on precious seconds from Black king bar and Shapeshift to fight.
* Aftershock reduces the effectiveness of his summons and can prove quite irritating for Lycan.
* Echo Slam is very powerful with the sheer amount of Lycan's units and will cause him to think twice when pushing towers.

* Primal Roar allows Beastmaster to keep Lycan in place after he used his Shapeshift.

* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with Aphotic Shield, or remove it from himself with Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.

* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Additional:
* Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and Light Strike Array can disable Mirana if she tries to Leap away.
* Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.

* Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* Shackleshot through tree with Focus Fire via Aghanim's Scepter​ combo can kill Mirana quickly, before using Leap or Moonlight Shadow.

* Kraken Shell grants him massive physical attack protection
* Anchor Smash will wipe the area, clearing Lycan's wolves.

* Arctic Burn allows Winter Wyvern to escape Lycan, even when he uses his ultimate.
* Splinter Blast is very effective in dealing with Lycan's summons.
* Cold Embrace saves allies from Lycan's raw physical damage and can buy allies enough time to turn the tide of battle.
* Winter's Curse stops Lycan in his tracks and is very effective because of his summons.
Additional:
* All of Lycan's damage is physical which is totally negated by Cold Embrace.
* Lycan often moves around with large amount of creeps, wolves created by Summon Wolves and neutral creep dominated by Helm of the Dominator which can be easily cleared by Splinter Blast or used as a great source of damage by Winter's Curse. If you catch Lycan with creeps nearby and affected by Shapeshift using Winter's Curse on him will most certainly end up with his death.

* Great Cleave will kill Lycan's summons very rapidly.
* Warcry will allow Sven and his allies to tank Lycan's damage, which is mainly physical.
* Storm Hammer will damage and stun Lycan's as well as his summons.

* All of Timbersaw's spells deal AoE damage, killing Lycan's summons very quickly.
* Reactive Armor will gain stacks quickly because of Lycan's summons.

* Her Mana Shield is too tough for Lycan to break.
* Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake

* Lycan's wolves deal little damage to Bristleback, and are easily killed by Quill Spray, even when they're invisible.
* Lycan's lack of burst damage makes it very hard for him to kill Bristleback, especially when his back is turned.
Additional:
* Quill Spray can be used to kill Lycan's summons.
* Bristleback allows him to stay alive against Lycan while dishing out counter attacks
* He can overpower Lycan with his Warpath instead.

* Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.

Additional:
* Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by Poof and Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Heroes who rely on summons will see them destroyed easily by Overwhelming Odds: Lycan, Arc Warden, Warlock, Chen

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, Wraith King, Visage.

* Heroes with summoned units don't fare well against Dawnbreaker. (Phantom Lancer ,Beastmaster ,Lycan)

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,Beastmaster

* Melee heroes who rely on summons, illusions or clones will trigger Counter Helix more often, thus taking more damage: Meepo, Lycan, Phantom Lancer

Additional:
* Berserker's Call can keep Lycan in place during his Shapeshift even through Black King Bar.
* Counter Helix is very effective against Lycan because of his summons.
* Culling Blade will prevent Lycan from running away with Shapeshift when he drops low.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Puck can initiate on Mirana with Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.

* Any Hero with high mobility will be neutralized by dream coil: Queen of Pain, Storm Spirit, Ember Spirit, Lycan, Bloodseeker, Anti-Mage, Timbersaw

* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki

* Heroes that heavily depend on illusions or summons, (Naga Siren, Terrorblade, Phantom Lancer, Lycan,...) are vulnerable to Sleight of Fist and even more so if Ember Spirit has Battle Fury.

* Heroes that can summon units will have their summons destroyed very quickly if badly micro-managed, like Chen, Lycan, and Phantom Lancer.

* Heroes who have summons, which can be quickly cleared by his powerful area of effect skill: Nature's Prophet, Enigma, Lycan

* Pugna's Decrepify prevents the target from taking physical damage or doing damage, which poses a huge problem for Lycan, as he mainly deals physical damage.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes who rely heavily on melee attacks and lack early spell immunity are easily blocked and interrupted by Ink Swell: Lycan, Ursa, Troll Warlord.

Additional:
* Stroke of Fate deals more damage when it hits more targets which makes it very effective in dealing with Lycan and his units.
* Soulbind prevents Lycan from running away and makes him very easy to deal with.

* Dragon Knight's insanely high armor and splash damage can cause Lycan to struggle taking him down.

* Can cast Demonic Conversion on one of Lycan's Wolves, making this a numbers fight.
* Malefice will greatly reduce his ability to engage
* Midnight Pulse can steep an area making it harder for Lycan to engage in.

* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.

* Blur is a real problem for Lycan, while she deals critical hits.

* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, Magnus

* Lycan relies heavily on right clicks making Untouchable very effective against him.
* If he tries to run away Impetus will do huge amounts of damage.
Additional:
* She can Enchant one of the wolves to her side.
* Untouchable still slows Lycan's attack speed.