Mirana
* If Slark sees the Sacred Arrow before it hits him, he can use 
Dark Pact to remove it a moment later.
* 
Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's 
Aghanim's Scepter combo with 
Shadow Dance.
Lycan
* 
Lycan cannot escape from a Pounce even if he uses 
Shapeshift, and has no disabling abilities to stop Slark.
Mirana
* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like 
Storm Spirit, 
Mirana, 
Anti-Mage and others won't be able to do much if they're caught.
Lycan
* 
Treant Protector grants protection against his attacks with 
Living Armor and his ultimate, 
Overgrowth is a massive AoE disarm and root that pierces spell immunity, causing trouble to Lycan. You will find yourself in need of an ally's dispel or forced to pop 
Black King Bar for its dispel.
Additional:
* Lycan has no kind of teleport, being only able to walk, and heavily relies on his attacks. As Overgrowth roots and disarms the targets, Lycan can't do much in an overgrowth field.
Mirana
* Heroes who rely on invisibility, such as 
Bounty Hunter, 
Clinkz, Mirana, 
Nyx Assassin and 
Riki, as they will be revealed if caught by Chronosphere.
Lycan
* 
Faceless Void can lock Lycan down with his 
Chronosphere pinning him down as long as his ultimate is up.
Mirana
* 
Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by 
Poof and 
Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Mirana
* Abaddon can remove Sacred Arrow's stun from his teammates with 
Aphotic Shield, or remove it from himself with 
Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.
Additional:
* 
Sacred Arrow can be instantly dispelled by Aphotic Shield.
Lycan
* Lycan is a hero focused entirely on single target physical damage and lacks disables or AoE damage. Due to this, he will have difficulties dealing with illusions or Naga Siren's Ensnare.
Mirana
* Though Mirana can clear waves of Broodmother's spiderlings with 
Starstorm, Broodmother will often stick with her spiderlings from 
Spawn Spiderlings, which in combination with the huge speed provided by 
Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys 
Orchid Malevolence and it's upgrade 
Bloodthorn, which allows her to prevent Mirana from escaping with both, 
Leap and 
Moonlight Shadow and from fighting back with Starstorm.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
Lycan
* 
Arctic Burn allows Winter Wyvern to escape Lycan, even when he uses his ultimate.
* 
Splinter Blast is very effective in dealing with Lycan's summons.
* 
Cold Embrace saves allies from Lycan's raw physical damage and can buy allies enough time to turn the tide of battle.
* 
Winter's Curse stops Lycan in his tracks and is very effective because of his summons.
Additional:
* All of Lycan's damage is physical which is totally negated by Cold Embrace.
* Lycan often moves around with large amount of creeps, wolves created by 
Summon Wolves and neutral creep dominated by 
Helm of the Dominator which can be easily cleared by Splinter Blast or used as a great source of damage by Winter's Curse. If you catch Lycan with creeps nearby and affected by Shapeshift using Winter's Curse on him will most certainly end up with his death.
Lycan
* 
Stroke of Fate deals more damage when it hits more targets which makes it very effective in dealing with Lycan and his units.
* 
Soulbind prevents Lycan from running away and makes him very easy to deal with.
Lycan
* A well landed 
Fissure can potentially take Lycan out of the fight for several seconds, who heavily relies on precious seconds from Black king bar and Shapeshift to fight.
* 
Aftershock reduces the effectiveness of his summons and can prove quite irritating for Lycan.
* 
Echo Slam is very powerful with the sheer amount of Lycan's units and will cause him to think twice when pushing towers.
Mirana
* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki
Lycan
* Vision from Charge of Darkness will easier to catch Lycan Shapeshift and Charge of Darkness out of reach Lycan Summon Wolves and Lycan's other creeps. Until upgrade Aghanim's Scepter faster catching Lycan Shapeshift
* 
Howl can dispell with Bulldoze.
Additional:
* Lycan's Shapeshift can easily to catch from Spirit Breaker's with 
Charge of Darkness.
Lycan
* Heroes with summons and illusions as Spirit Breaker has no strong AoE capabilities to deal with them: 
Chaos Knight, 
Phantom Lancer, 
Terrorblade, 
Naga Siren, 
Broodmother, 
Warlock, 
Visage, 
Nature's Prophet, 
Shadow Shaman, Lycan.
Mirana
* 
Track detects Mirana and her allies during Moonlight Shadow.
Lycan
* 
Quill Spray can be used to kill Lycan's summons.
* 
Bristleback allows him to stay alive against Lycan while dishing out counter attacks
* He can overpower Lycan with his 
Warpath instead.
Additional:
* Lycan's wolves deal little damage to Bristleback, and are easily killed by Quill Spray, even when they're invisible.
* Lycan's lack of burst damage makes it very hard for him to kill Bristleback, especially when his back is turned.
Lycan
* Brewmaster can waste a large portion of Lycan's ultimate by putting him in Cyclone.
* Lycan has no way to stop Brewmaster from using Primal Split by himself.
* Lycan's team often tries to push towers as a group, and Brewmaster excels at winning teamfights while trying to defend a tower.
Mirana
* 
Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and 
Light Strike Array can disable Mirana if she tries to Leap away.
* 
Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.
Additional:
* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Lycan
* 
Kraken Shell grants him massive physical attack protection
* 
Anchor Smash will wipe the area, clearing Lycan's wolves.
Lycan
* Her 
Mana Shield is too tough for Lycan to break.
* 
Mystic Snake can hit for a massive damage once it spread between his summons.
Additional:
* Can be easily petrified despite his speed.
* Summoned wolves will be targeted by Split Shot or Mystic Snake
Lycan
* 
Great Cleave will kill Lycan's summons very rapidly.
* 
Warcry will allow Sven and his allies to tank Lycan's damage, which is mainly physical.
* 
Storm Hammer will damage and stun Lycan's as well as his summons.
Lycan
* 
Primal Roar allows Beastmaster to keep Lycan in place after he used his Shapeshift.
Lycan
* All of Timbersaw's spells deal AoE damage, killing Lycan's summons very quickly.
* 
Reactive Armor will gain stacks quickly because of Lycan's summons.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, 
Zeus and 
Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, 
Outworld Destroyer, 
Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Lycan
* Jakiro's area-of-effect abilities make him strong against heroes who rely on illusions and summons: Terrorblade, Naga Siren Chaos Knight, Phantom Lancer, Broodmother, Nature's Prophet, Lycan, 
Wraith King, Visage.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, 
Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Lycan
* 
Pugna's 
Decrepify prevents the target from taking physical damage or doing damage, which poses a huge problem for Lycan, as he mainly deals physical damage.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Lycan
* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: 
Phantom Assassin, 
Juggernaut, 
Dragon Knight, Lycan, 
Ursa, 
Troll Warlord
Additional:
* 
Guardian Angel completely negates all of Lycan's damage since Lycan mainly deals physical damage.
* 
Purification can also be a problem for Lycan, as Purification deals damage around the target, which poses a problem for him and his summons.
Lycan
* Heroes who summon multiple units that are not spell immune. Nature's Prophet,Lycan,
Beastmaster
Lycan
* Heroes who rely on physical damage output to be effective will fare badly against Muerta's 
Pierce the Veil: Phantom Assassin, Terrorblade, 
Drow Ranger, 
Lifestealer, Anti-Mage, 
Alchemist, Lycan, Clinkz, 
Sniper.
Lycan
* Melee heroes who rely on summons, illusions, or clones will trigger Counter Helix more often, thus taking more damage: 
Meepo, Lycan, Phantom Lancer
Additional:
* 
Berserker's Call can keep Lycan in place during his Shapeshift even through Black King Bar.
* 
Counter Helix is very effective against Lycan because of his summons.
* 
Culling Blade will prevent Lycan from running away with Shapeshift when he drops low.
Lycan
* Heroes that can summon units will have their summons destroyed very quickly if badly micro-managed, like 
Chen, Lycan, and Phantom Lancer.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Lycan
* Heroes who rely on summons will see them destroyed easily by Overwhelming Odds: Lycan, 
Arc Warden, Warlock, Chen
Mirana
* Heroes that cannot move in fights such as a 
Dueling Legion Commander or anyone channeling a spell like 
Bane, 
Pudge, or 
Enigma are easy Sacred Arrow targets.
Lycan
* Heroes with summoned units don't fare well against Dawnbreaker. (Phantom Lancer ,Beastmaster ,Lycan).
Mirana
* Puck can initiate on Mirana with 
Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in 
Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with 
Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.
Lycan
* Any Hero with high mobility will be neutralized by dream coil: Queen of Pain, Storm Spirit, 
Ember Spirit, Lycan, 
Bloodseeker, Anti-Mage, 
Timbersaw.
Lycan
* A Lycan with Shapeshift can always run down Puck for a very quick kill due to its low armor. It is important to abuse as many cliffs and trees as possible to escape from a Lycan.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Lycan
* Dragon Knight's insanely high armor and splash damage can cause Lycan to struggle taking him down.
Lycan
* Heroes who have summons, which can be quickly cleared by his powerful area of effect skill: Nature's Prophet, Enigma, Lycan
Lycan
* Heroes that heavily depend on illusions or summons, (Naga Siren, Terrorblade, Phantom Lancer, Lycan,...) are vulnerable to Sleight of Fist and even more so if Ember Spirit has 
Battle Fury.
Mirana
* Heroes with silences and hard stuns such as 
Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Additional:
* All abilities from Mirana can shut down with 
Doom and Mirana can not escape with Leap since Doom activated.
* Doom also catch Mirana disabled used combo items Doom from ugrade Aghanim's Scepter and 
Blink Dagger or 
Overwhelming Blink make Mirana can not move escaping notably Leap and Moonlight Shadow.
Mirana
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from 
Eclipse with Moonlight Shadow, smart Luna can buy 
Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Mirana
* A couple of long-range heroes with excellent laning like Mirana, 
Lina, 
Necrophos, 
Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Mirana
* 
Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* 
Shackleshot through tree with 
Focus Fire via Aghanim's Scepter combo can kill Mirana quickly, before using Leap or Moonlight Shadow.
Lycan
* Windranger's has bad against Hero heavily strong escape out of reach with windrun: 
Spirit Breaker, Lycan, Storm Spirit, 
Earth Spirit
Lycan
* Can cast 
Demonic Conversion on one of Lycan's Wolves, making this a numbers fight.
* 
Malefice will greatly reduce his ability to engage
* 
Midnight Pulse can steep an area making it harder for Lycan to engage in.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Lycan
* Phantom Assassin's 
Blur is a real problem for Lycan, as he relies entirely on direct attacks to deal damage.
Lycan
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Mirana
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, 
Magnus
Lycan
* Lycan relies heavily on right clicks making Untouchable very effective against him.
* If he tries to run away Impetus will do huge amounts of damage.
Additional:
* She can 
Enchant one of the wolves to her side.
* Lycan will struggle greatly to harm Enchantress through her 
Untouchable which can seriously slow down Lycan's attack speed even if Lycan is spell immune.
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or 
Enchantress.
Lycan
* Heroes with haste can negate Enchant's slow: 
Weaver, 
Dark Seer, Lycan, 
Centaur Warrunner.
Mirana
* Techies spends lots of time standing still planting stacks of 
Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use 
Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.
Lycan
* He can send wolves to defuse 
Proximity Mines, and he can catch up Techies and kill him before they can deny themselves. Even if the suicide is successful, Lycan can still survive because of his tankiness.
Mirana
* Mirana can use Leap to jump right next to Drow Ranger or can approach her while under cover of the invisibility granted by Moonlight Shadow, which cancels the bonus granted to Drow Ranger by 
Marksmanship.
* Her low health makes her easy to burst down with Mirana's spells, especially with Aghanim's Scepter.
* Mirana can dodge 
Gust with good reaction time, or Leap away if Drow tries to slow her without Gust.
Lycan
* Shapeshift allows Lycan to get close and disable Marksmanship.
* Shapeshift also makes him immune to slows like Drow Ranger's Frost Arrows.
Additional:
* The Wolves's speed causes the knockback from Gust to be ineffective.
* Drow Ranger lacks escapes and loses her Marksmanship when someone is near her. Lycan can take advantage of these weaknesses of Drow Ranger.
Mirana
* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build 
Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.
Lycan
* Shapeshift increases Lycan's movement speed and renders him unslowable, allowing him to easily avoid and escape Ancient Apparition's abilities.
* Lycan has fast summons, both his wolves from Summon Wolves can do heavy damage to Ancient Apparition due to his immobility and low armor.
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or Enchantress.
Lycan
* Lycan can clear waves of Chen's creeps with his wolves from Summon Wolves, especially once Lycan takes +2 Wolves summoned talent. And even though Chen can convert one of his wolves with 
Holy Persuasion, Lycan can counter this by buying 
Helm of the Overlord to regain control of it. Uncontrollable wolves summoned from 
Aghanim's Shard upgrade Summon Wolves cannot be converted with Holy Persuasion.
* Shapeshift allows him to chase down Chen and kill him easily.
* Howl can reduce attack damage of both, Chen and his creeps.
Mirana
* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys 
Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and 
Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.
Mirana
* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If 
Frostbite has already been used, Mirana can Leap away even when slowed by 
Crystal Nova or 
Freezing Field.
Lycan
* Shapeshift allows Lycan to chase down Earth Spirit.
Lycan
* Lycan's ultimate makes him immune to slows from Ursa's 
Earthshock as well as allowing him to outmaneuver Ursa during 
Enrage. Lycan can also easily chase down Ursa while shapeshifted, should Ursa try to flee.
Lycan
* Howl reduces a good chunk of Marci's attack damage that she relies heavily on, and the armor reduction works better on her because of her low armor.
* Shapeshift renders Lycan immune to slow from Rebound and Unleash.
Lycan
* Shapeshift allows Lycan to escape from Upheaval with maximum movement speed.
* Warlock doesn't have a good solution to deal with Lycan's wolves from Summon Wolves.
Lycan
* Lycan doesn't care much about Lich's slows thanks to Shapeshift.
* Chain Frost can bounce to the wolves that Lycan summons.
Additional:
* 
Lich possesses a lot of slows, which Lycan doesn't care about when he Shapeshifts.
* Lich has no in-built escape, which makes him a good target for Lycan.
Lycan
* Lycan's high health allows him to easily shrug off Nyx Assassin's burst damage and fend him off.
* As Lycan commonly buys Black King Bar, he can use it to freely attack Nyx Assassin and chase after him with Shapeshift.
Mirana
* Mirana can disturb Shadow Shaman's channeling even if he is under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying towards Shadow Shaman can continue for the whole match.
Lycan
* The movement speed granted from Shapeshift means that Spectre has no way to punish Lycan if he wants to splitpush or pick off supports. Furthermore, he will kite 
Haunt and cannot be slowed by 
Spectral Dagger.
* Lycan is often part of an early game push strategy which is often the best counter to Spectre because she needs a lot of time and space to come online as a late game carry.
Lycan
* Heroes who can summon illusions and summons because Terrorblade has no abilities to deal with multiple enemies at once outside Reflection: Shadow Shaman, Naga Siren, Broodmother, Lycan, Enigma, Chaos Knight, Phantom Lancer, Shadow Demon, Dark Seer, Nature's Prophet, 
Invoker, 
Morphling, Visage, 
Grimstroke with Aghanim's Scepter.
Lycan
* Multiple attackers thanks to summoned units or clones: Meepo, 
Witch Doctor, Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her 
Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: 
Slark, 
Gyrocopter, Queen of Pain, Shadow Shaman (
Shackles), 
Jakiro, Pugna, Doom
Lycan
* You can easily kill a squishy Sniper, due to your high movement speed and his lack of escape.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates difficult targets to hook.
* Sacred Arrow can be used to cancel Dismember from long distances.
Lycan
* Heroes who do not have nor rely on passive abilities make Nethertoxin much less effective: Clinkz, Pugna, Nature's Prophet, Dark Seer, Lycan, 
Tusk
Lycan
* Once you get a Black King Bar, squishy spellcasters like Zeus, 
Skywrath Mage and others will be probably easy to deal with.
Mirana
* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.
Lycan
* Heroes with summons: Lycan, Broodmother, Visage, Nature's Prophet, Warlock.
Mirana
* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, 
Luna, Meepo, Mirana, 
Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, 
Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Lycan
* Heroes with single-target abilities will be overwhelmed by Lycan and his summons: Wraith King, Bane, Phantom Assassin.
Mirana
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Lycan
* Heroes with low armor and little mobility, like 
Huskar, 
Io, etc. will also have an unfortunate fate.
Lycan
* Heroes with low armor and little mobility, like Huskar, Io, etc. will also have an unfortunate fate.
Lycan
* Heroes with single-target abilities will be overwhelmed by Lycan and his summons: Wraith King, Bane, Phantom Assassin.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Lycan
* Shapeshift is useful for killing or escaping Silencer.
* Summon Wolves, can be used to hunt and harass silencer - even when Lycan himself can't fight.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Counterspell does not protect Anti-Mage from Sacred Arrow.
* Moonlight Shadow can help her allies avoid Mana Break and Mana Void.
* Blink's cooldown isn't short enough to escape from Leap, especially when she has the extra charge from Aghanim's Shard.
Additional:
* Combo items for Mirana 
Rod of Atos can upgrade to 
Gleipnir and Sacred Arrow before and during Anti-Mage build item Manta Style cooldown can easy penetrates Counterspell broken.
* Charge for Leap can Mirana easily faster escaping.
* Moonlight Shadow it can disappear anytime and Anti-Mage can not fight.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Mirana
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or 
Leshrac's 
Split Earth, or combos like 
Kunkka's 
X Marks the Spot into 
Torrent.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Lycan
* Lycan and Weaver has abilities that allow them to move at maximum movement speed, and those abilities can't be dispelled, potentially wasting the slow from Demonic Purge.
Lycan
* 
Keeper of the Light has a blind, which causes Lycan to miss his attacks.
Lycan
* Heroes with hastes: Dark Seer, Lycan
Mirana
* The long silence of 
Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With 
Dark Ascension and 
Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Lycan
* Void's slow is useless against Lycan by activating Shapeshift.
* Night Stalker's single target abilities (with the exception of Void upgraded by Aghanim's Scepter) is not very effective against Lycan's Summon Wolves during the early and mid game.
Lycan
* Paralyzing cask bounces between him and his wolves, keeping him stunned for long amounts of time.
Mirana
* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* 
Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.
Lycan
* Zeus can deal a huge amount of damage, but he lacks defensive abilities, such as good mobility or resistance. Due to that, he doesn't like to be touched by any means. Heroes with higher damage output and good mobility will often get easily near Zeus and trade damage (eventually causing Zeus's downfall). Such Heroes include: Lycan, Slark, Storm Spirit, 
Spectre and others.
Lycan
* Tidebringer's cleave will cripple any of his summons.
* Could potentially build Heaven's Halberd to cripple Lycan even more.
Additional:
* 
Tidebringer can be used to kill Lycan's summons.
* Can also build into 
Heaven's Halberd which will disable Lycan's auto attacks, crippling him even more.
Mirana
* Leap allows Mirana to easily escape Torrent and Ghostship.
Mirana
* 
Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place 
Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
Additional:
* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Lycan
* Magnetic Field is useless against melee heroes, so Lycan can attack Arc Warden without missing.
* Flux doesn't affect Lycan that much, because Shapeshift grants immunity to slows and because he is never alone.
* If their 
Tempest Double has been called, Lycan can still kill Arc Warden before the double expires.
Mirana
* Thirst detects Mirana or her ally at low health during
Moonlight Shadow.
Leap.
Rupture can quickly kill Mirana if she tries to Leap away.
Thirst detects Mirana and her allies during Moonlight Shadow.
* Rupture deals high damage when Mirana uses
Additional:
*
*
Lycan
* Rupture completely negates Lycan's high mobility.
Rupture completely negates Lycan's high mobility.
Bloodrage.
* All of Lycan's summons are good sources of healing with Bloodrage.
Additional:
*
* All of Lycan's summons are good sources of healing with