Mirana
* The long silence of 
Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With 
Dark Ascension and 
Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Queen of Pain
* Night Stalker has a huge, almost instant silence through Crippling Fear. The main problem is that he can get it off while Queen of Pain barely has any vision of him if he creeps up to her during Dark Ascension. She'll have to play very carefully before she gets a 
Black King Bar or a 
Eul's Scepter of Divinity.
Mirana
* Thirst detects Mirana or her ally at low health during 
Moonlight Shadow.
* Rupture deals high damage when Mirana uses 
Leap.
Additional:
* 
Rupture can quickly kill Mirana if she tries to Leap away.
* 
Thirst detects Mirana and her allies during Moonlight Shadow.
Queen of Pain
* Blood Rite prevents Queen of Pain from escaping with 
Blink.
* Blink will trigger the extra damage from Rupture.
Additional:
* 
Blood Rite silences her, preventing her from initiating or escaping.
* With Thirst, even if she Blinks away, Bloodseeker can catch right up to her.
* Rupture will heavily damage Queen of Pain if she tries to Blink away.
* She is, however, one of the few heroes who can avoid the damage from Rupture if she successfully blink-walks.
Mirana
* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Additional:
* Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and 
Light Strike Array can disable Mirana if she tries to Leap away.
* 
Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.
Queen of Pain
* Lina has a very long range of attack, which completely overlaps the range of Queen of Pain's abilities and attacks, which is why even a single 
Shadow Strike roll can become deplorable, since Lina will shoot Queen of Pain from a long distance before and after the Shadow Strike roll. And with the help of the abilities of Light Strike Array and Laguna Blade, Lina can even kill Queen of Pain because of her small health reserve if she is exposed to a blow
Additional:
* Lina has a very long range of attack, which completely overlaps the range of Queen of Pain's abilities and attacks, which is why even a single Shadow Strike roll can become deplorable, since Lina will shoot Queen of Pain from a long distance before and after the Shadow Strike roll. And with the help of Light Strike Array and Laguna Blade, Lina can even kill Queen of Pain because of her small health reserve if she is exposed to a blow.
Mirana
* 
Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.
Additional:
* 
Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by 
Poof and 
Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Queen of Pain
* Chain of Earthbinds prevents her from using Blink, allowing Meepo to quickly kill her with Poof and attacks.
* Meepo tends to buy items with attributes, mitigating Queen of Pain's magical burst.
Additional:
* Meepo is the hard counter for Queen of Pain - chaining Earthbinds prevents her from using Blink for a long time, and without any other escape options, Queen of Pain cannot survive several Poofs and attacks.
* Meepo tends to build items with attributes, mitigating Queen of Pain's magical burst.
Mirana
* Heroes with silences and hard stuns such as 
Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Queen of Pain
* 
Glaives of Wisdom's intelligence steal will heavily punish Queen of Pain, as the loss of intelligence means that her mana pool is also reduced, since she is heavily reliant on her abilities to be able to make an impact.
* In the laning stage, Queen of Pain's reliance on spamming Shadow Strike and Scream of Pain will be significantly hindered by 
Arcane Curse.
* 
Last Word and 
Global Silence will render Queen of Pain defenseless unless she has an item/ally to dispel the silence.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: 
Anti-Mage, 
Queen of Pain, 
Storm Spirit, 
Riki.
Queen of Pain
* Smoke Cloud prevents Queen of Pain from using any of her offensive and defensive spells, rendering her unable to effectively react to Riki's attack.
* It's easy to dodge 
Sonic Wave by using Blink Strike & Tricks of the Trade.
Mirana
* Heroes who rely on invisibility, such as 
Bounty Hunter, 
Clinkz, Mirana, 
Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Queen of Pain
* Time Dilation affects Queen of Pain's low cooldown abilities, making them unusable for a long time, rendering Queen of Pain nearly useless.
* Chronosphere provides excellent lockdown against Queen of Pain, allowing for reliable kills in all stages of the game.
Additional:
* 
Time Walk and 
Backtrack allows Faceless Void to easily negate Queen of Pain's burst damage.
* 
Chronosphere prevents Queen of Pain from escaping with Blink, and her low survivability makes her an easy kill.
* 
Time Dilation will prevent Queen of Pain from using her low-cooldown spells or force her to buy Black King Bar or a Eul's Scepter of Divinity to dispel the debuff and re-engage.
Mirana
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from 
Eclipse with Moonlight Shadow, smart Luna can buy 
Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade 
Sacred Arrow, giving Mirana difficulties in hitting her with it.
* 
Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Queen of Pain
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for 
Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Additional:
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Mirana
* A couple of long-range heroes with excellent laning like Mirana, 
Lina, 
Necrophos, 
Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Mirana
* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with 
Aphotic Shield, or remove it from himself with 
Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.
Mirana
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, 
Outworld Destroyer, 
Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Queen of Pain
* 
Duels prevents Queen of Pain from using Blink, which may force her to purchase a 
Linken's Sphere
* Because Queen of Pain is also not a right-click hero, Legion won't have much difficulties in duels.
* 
Press the Attack dispels Shadow Strike's debuff.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like 
Bane, 
Pudge, or 
Enigma are easy Sacred Arrow targets.
Mirana
* Though Mirana can clear waves of Broodmother's spiderlings with 
Starstorm, Broodmother will often stick with her spiderlings from 
Spawn Spiderlings, which in combination with the huge speed provided by 
Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys 
Orchid Malevolence and it's upgrade 
Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to 
Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, and prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Mirana
* 
Track detects Mirana and her allies during Moonlight Shadow.
Queen of Pain
* A good Centaur can catch Queen of Pain with a 
Blink Dagger and 
Hoof Stomp.
* 
Retaliate with 
Blade Mail reflects all of Queen of Pain's damage, especially Sonic Wave.
* 
Stampede grants a movement speed bonus, which can prevent Queen of Pain from initiating.
* 
Double Edge can shred her low health pool if she's not careful.
Queen of Pain
* A good Skywrath Mage with quick fingers will punish Queen of Pain for blinking aggressively. 
Ancient Seal is a six second silence with no cast time, so he can interrupt either her Shadow Strike or Sonic Wave, and a good 
Mystic Flare on top of that will seal the deal for her.
* Ancient Seal also has pretty good range so he could get it off before she blinks away.
Queen of Pain
* Blink and positioning is crucial for Queen of Pain. These factors are heavily countered by a good Glimpse.
* Static Storm is devastating for Queen as she relies heavily on her spells to inflict heavy burst damage.
Additional:
* 
Thunder Strike gives vision of Queen of Pain when she's trying to escape. When combined with 
Glimpse, her mobility and hit-and-run style can be negated.
* While in a team fight, 
Static Storm forces Queen of Pain to only use right-clicks.
* When combined with the 
Kinetic Field, she can only wait until she respawns.
Queen of Pain
* A good Nyx can reflect Queen of Pain's Sonic Wave with his 
Spiked Carapace, or even initiate a gank on her in 
Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a 
Dagon, provided he can get his full combo off.
Queen of Pain
* All of Queen of Pain's abilities are worthy choices for Rubick to 
Spell Steal. In addition, he can cast her abilities from further distances than her thanks to 
Arcane Supremacy's increased cast range and spell amplification.
Mirana
* Mirana's Leap is ineffective if Lycan uses 
Shapeshift. It also allows him to dodge Sacred Arrow.
Mirana
* Puck can initiate on Mirana with 
Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in 
Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with 
Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.
Queen of Pain
* Any Hero with high mobility will be neutralized by dream coil: Queen of Pain, Storm Spirit, 
Ember Spirit, 
Lycan, 
Bloodseeker, Anti-Mage, 
Timbersaw.
Additional:
* Puck will make a game of dodging as many Shadow Strikes as he can with Phase Shift. If he's a good player, he will also dodge Sonic Wave. If he's a great player, he will also dodge Scream of Pain, and it's all thanks to this single spell.
* Puck also has a silence in Waning Rift to prevent Queen of Pain from blinking away.
* Puck can provide vision to hunt her down if she blinks into the trees with 
Illusory Orb.
* If Queen of Pain is under the effect of Dream Coil, she will be unable to blink out.
Queen of Pain
* Once you farm up an Orchid Malevolence or a 
Scythe of Vyse, you're suddenly a lot more fearsome to elusive heroes like Storm Spirit or even that pesky 
Puck.
Mirana
* 
Doom completely takes Mirana out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like Storm Spirit, Mirana, Anti-Mage and others won't be able to do much if they're caught.
Queen of Pain
* Heroes with gap-closing abilities will be easy targets for Berserker's Call: 
Phantom Assassin, 
Faceless Void, 
Slark, 
Chaos Knight, 
Morphling, Queen of Pain
Additional:
* 
Berserker's Call prevents Queen of Pain from escaping with Blink and also pierces her Black King Bar.
* Due to her fast attack speed from 
Mjollnir, it will quickly trigger 
Counter Helix.
* 
Culling Blade finishes off Queen of Pain's low health pool before she gets a chance to escape, preventing her from playing the hit-and-run style often associated with Queen of Pain.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Queen of Pain
* In early to mid stage, Silence is also a great way to counter escape oriented heroes such as Anti-Mage, Queen of Pain, and Phantom Assassin to prevent them from escaping, provided that they don't have any basic dispels.
Additional:
* 
Silence will prevent Queen of Pain from using Blink to escape or chase.
* If Queen of Pain uses Blink to close the gap to Death Prophet, Death Prophet will be in range for 
Spirit Siphon and typically gain an advantage over Queen of Pain.
Mirana
* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki
Queen of Pain
* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin
Queen of Pain
* Heroes that usually build Linken's Sphere as either a core or situational item: 
Weaver, 
Medusa, Morphling, Queen of Pain, Storm Spirit, 
Luna, 
Naga Siren.
Mirana
* If Slark sees the Sacred Arrow before it hits him, he can use 
Dark Pact to remove it a moment later.
* 
Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter combo with 
Shadow Dance.
Queen of Pain
* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, 
Earth Spirit, Faceless Void, 
Magnus, Mirana, 
Monkey King, Morphling, 
Pangolier, Phantom Assassin, 
Phoenix, Puck, Queen of Pain, Riki, 
Sand King, 
Spirit Breaker, Timbersaw, 
Tusk.
Queen of Pain
* Both Scream of Pain and Sonic Wave should hit Slark during his Shadow Dance.
Queen of Pain
* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like 
Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Queen of Pain
* Because Queen of Pain's spells cost a decent amount of mana, Anti-Mage can easily use 
Mana Void if she spams her spells recklessly.
* Anti-Mage has similar mobility through 
Blink, which can allow him to catch up to or flee from her.
* 
Counterspell will reduce the damage done by Shadow Strike and Scream of Pain. Additionally, its active component also reflects Shadow Strike back at her if Anti-Mage times it right.
Mirana
* Counterspell does not protect Anti-Mage from Sacred Arrow.
* Moonlight Shadow can help her allies avoid Mana Break and Mana Void.
* Blink's cooldown isn't short enough to escape from Leap, especially when she has the extra charge from 
Aghanim's Shard.
Additional:
* Combo items for Mirana Rod of Atos can upgrade to 
Gleipnir and Sacred Arrow before and during Anti-Mage build item 
Manta Style cooldown can easy penetrates Counterspell broken.
* Charge for Leap can Mirana easily faster escaping.
* Moonlight Shadow it can disappear anytime and Anti-Mage can not fight.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, 
Zeus and 
Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Queen of Pain
* High priority targets like Queen of Pain, 
Drow Ranger, Ember Spirit can't get caught out from Lion's long range disables, making it harder to them fulfill their roles, and making it easy to target them.
Mirana
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or 
Leshrac's 
Split Earth, or combos like 
Kunkka's 
X Marks the Spot into 
Torrent.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, 
Phantom Lancer, 
Nature's Prophet.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Queen of Pain
* Heroes who rely on high mobility are especially vulnerable to Primal Roar: Storm Spirit, Ember Spirit, Queen of Pain.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Queen of Pain
* Heroes that rely on their high mobility such as Queen of Pain, Slark and Weaver can be constantly engaged against due to your excellent ability to chase over any terrain. Make sure you carry true sight items (such as Dust of Appearance or Gem of True Sight) for invisible heroes that could potentially escape your clutches.
Queen of Pain
* Queen of Pain outlanes Storm Spirit due to the fact that it has long-range abilities: Shadow Strike and 
Scream Of Pain. Storm Spirit's damage from the 
Overload ability is not enough to interrupt her on the line, and the 
Static Remnant will never reach Queen Of Pain, as she will scatter her abilities from afar, which is why she will drive Storm Spirit off the line and get a lot of gold and level, after such a stage of the liner, Queen of Pain will very quickly buy Black King Bar and will not let Storm Spirit catch and kill her at the expense of 
Electric Vortex
Additional:
* Queen of Pain outlanes Storm Spirit due to the fact that it has long-range abilities: Shadow Strike and Scream Of Pain. Storm Spirit's damage from the Overload ability is not enough to interrupt her on the line, and the Static Remnant will never reach Queen Of Pain, as she will scatter her abilities from afar, which is why she will drive Storm Spirit off the line and get a lot of gold and level, after such a stage of the liner, Queen of Pain will very quickly buy Black King Bar and will not let Storm Spirit catch and kill her at the expense of Electric Vortex
Mirana
* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.
Queen of Pain
* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, Queen of Pain, Phantom Assassin, 
Windranger, Bounty Hunter, Spirit Breaker, 
Night Stalker, Storm Spirit, 
Juggernaut, etc.
Queen of Pain
* Heroes reliant on abilities to output damage or escape can be shut down by Gust: Queen of Pain.
Mirana
* Mirana can use Leap to jump right next to Drow Ranger or can approach her while under cover of the invisibility granted by Moonlight Shadow, which cancels the bonus granted to Drow Ranger by 
Marksmanship.
* Her low health makes her easy to burst down with Mirana's spells, especially with Aghanim's Scepter.
* Mirana can dodge 
Gust with good reaction time, or Leap away if Drow tries to slow her without Gust.
Queen of Pain
* Often you can burst Drow Ranger down before she has a chance to try and Gust you away. Try to have a teammate bait her Gust out before you Blink and get the drop on her.
Queen of Pain
* Queen of Pain can be an effective tool against Batrider in the game and on the line. She has long-range abilities such as Scream of Pain or Sonic Wave and a long-range type of attack, which is why she can keep Batrider at a distance all the time, and prevent him from attacking with 
Flaming Lasso or 
Firefly. Queen of Pain has an effective high-deceleration ability against Batrider - Shadow Strike, which is why he cannot quickly set fire to all enemies under Firefly and fly between all Queen of Pain allies. In addition, Queen of Pain has a wonderful escape in stock - Blink, which can save her at any moment in which batrider decides to attack
Additional:
* Queen of Pain can be an effective tool against Batrider in the game and on the line. She has long-range abilities such as Scream of Pain or Sonic Wave and a long-range type of attack, which is why she can keep Batrider at a distance all the time, and prevent him from attacking with Flaming Lasso or Firefly. Queen of Pain has an effective high-deceleration ability against Batrider - Shadow Strike, which is why he cannot quickly set fire to all enemies under Firefly and fly between all Queen of Pain allies. In addition, Queen of Pain has a wonderful escape in stock - Blink, which can save her at any moment in which batrider decides to attack
Mirana
* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and 
Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.
Mirana
* Techies spends lots of time standing still planting stacks of 
Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use 
Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.
Queen of Pain
* Blink allows Queen of Pain to avoid ganks and keep her distance, preventing Monkey King from building up Jingu Mastery.
* Scream of Pain and Sonic Wave will hit Monkey King when he is disguised, or on a tree.
* The large AoE and low cooldown also helps Queen of Pain hit the real Monkey King inside of Wukong's Command.
Queen of Pain
* Queen of Pain usually outlanes Invoker, giving her team a significant early game advantage while Invoker is still farming.
* Blink allows Queen of Pain to escape from Invoker's combo if he doesn't have disables.
Queen of Pain
* Blink makes it hard for Gyrocopter to pin down Queen of Pain.
* Sonic Wave is very effective at ganking Gyrocopter in the early game.
Queen of Pain
* Husker is the kind of hero that likes to remain at low health, which is perfect for Queen of Pain to burst with Sonic Wave.
* She should be able to Blink away after he jumps on her with 
Life Break.
Queen of Pain
* Blink can instantly break Static Link, making it useless against her.
* Queen of Pain doesn't fully rely on her physical attack damage, so she can still fight after being hit with Static Link.
Mirana
* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* 
Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
Queen of Pain
* Queen of Pain can Blink to both escape and initiate onto Void Spirit.
* She is also a very common Orchid Malevolence carrier, which can prevent Void Spirit from contributing much in fights.
Queen of Pain
* Blink allows Quen of Pain to easily escape ganking or initiating attempts with Hookshot and Power Cogs.
Queen of Pain
* Queen of Pain can easily escape Chain Frost thanks to Blink.
* His low survivability makes an easy kill for Shadow Strike, Scream of Pain & Sonic Wave.
Mirana
* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: 
Lifestealer, Doom, Mirana, Clinkz.
Queen of Pain
* Heroes with mobility spells (such as Queen of Pain's Blink and 
Clockwerk with 
Hookshot) can easily avoid 
Lil' Shredder and 
Mortimer Kisses.
* Heroes with high movement speeds like 
Pugna and 
Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
Mirana
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: 
Arc Warden, 
Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and 
Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, Magnus
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or 
Enchantress.
Queen of Pain
* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage
Additional:
* Queen of Pain often relies more on abilities than right-clicks, making 
Untouchable nearly useless against her.
* Enchantress also has a lower health pool than Queen of Pain, making her vulnerable to Queen of Pain's damage burst.
Queen of Pain
* Heroes with considerable mobility can easily escape from a rolling Pangolier: Anti-Mage, Queen of Pain, 
Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, moreover, if a player is familiar with how Rolling Thunder works, they can adjust their movement to avoid it entirely and of course outplay the Pangolier player.
Queen of Pain
* Weak damage but high tick rate or persist in a long time: Slark, 
Gyrocopter, Queen of Pain, 
Shadow Shaman (
Shackles), 
Jakiro, Pugna, Doom
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, 
Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her 
Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna, Doom
Queen of Pain
* Heroes with mobility spells can quickly escape from Stroke of Fate or break out of Soulbind: Anti-Mage, Queen of Pain, Morphling, Storm Spirit
Queen of Pain
* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, 
Io, Nature's Prophet, Pangolier, Puck, Queen of Pain and most notably Riki.
Queen of Pain
* Heroes with teleports to escape Solar Blind and Will-O-Wisp: Phantom Assassin, Puck, Queen of Pain, Storm Spirit
Queen of Pain
* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain
Queen of Pain
* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.
Queen of Pain
* Heroes who recklessly jump on Pudge with their gap-closing abilities will be easy targets for Pudge's Meat Hook and Dismember Combo: Phantom Assassin, Faceless Void, Queen of Pain etc.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates difficult targets to hook.
* Sacred Arrow can be used to cancel Dismember from long distances.
Queen of Pain
* Heroes with a high degree of mobility and invisibility are hard to catch with Meat Hook: Ember Spirit, Riki, Clinkz, Queen of Pain.
Queen of Pain
* Blinking heroes like Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.
Queen of Pain
* Heroes with escaping and disjointing abilities can be good against Juggernaut:Anti-Mage Riki, Queen of Pain, Puck, Storm Spirit, Ember Spirit, Slark etc.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Mirana
* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.
Queen of Pain
* Dark Seer's only disable is Vacuum. Though he starts off with high armor and health, he'll eventually have a hard time dealing with high mobility heroes such as Weaver or Queen of Pain.
Queen of Pain
* Heroes who have a high mobility (Queen of Pain, Storm Spirit, Slark, etc.).
Queen of Pain
* Queen of Pain can be a good hero for dealing with Ember Spirit with Orchid Malevolence, her pure damage nuke in Sonic Wave and a slow in Shadow Strike. However, Queen of Pain can be punished by Ember Spirit, as his Searing Chains prevents her from getting Blink off.
Queen of Pain
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, 
Dawnbreaker's 
Solar Guardian, 
Axe's Berserker's Call, 
Mars's 
Arena of Blood, Jakiro's 
Macropyre, 
Dual Breath and 
Ice Path, Naga Siren's 
Song of the Siren, 
Razor's 
Eye of the Storm and 
Plasma Field, Lina's Light Strike Array, 
Broodmother's Spinner's Snare from Aghanim's Scepter, 
Elder Titan's 
Earth Splitter and 
Echo Stomp, 
Alchemist's 
Unstable Concoction and 
Acid Spray, Queen of Pain's Sonic Wave, 
Dark Seer's 
Wall of Replica and 
Vacuum, 
Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's 
Black Hole and 
Midnight Pulse, 
Shadow Fiend's 
Requiem of Souls, 
Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, 
Flamebreak and 
Sticky Napalm, 
Ancient Apparition's 
Ice Blast, Sand King's 
Epicenter, 
Sand Storm and 
Burrowstrike, Gyrocopter's 
Call Down, Ember Spirit's 
Sleight of Fist, Death Prophet's 
Exorcism and Silence, Monkey King's 
Wukong's Command, 
Crystal Maiden's 
Freezing Field, 
Muerta's 
The Calling, Medusa's 
Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, Pangolier's 
Swashbuckle, 
Grimstroke's 
Soulbind, 
Ink Swell and 
Stroke of Fate, 
Earthshaker's 
Echo Slam and 
Fissure, Puck's Dream Coil and Waning Rift, 
Winter Wyvern's 
Winter's Curse, Magnus's 
Reverse Polarity.
Queen of Pain
* Heroes with damage over time abilities can quickly eat through Gravekeeper's Cloak charges like 
Huskar, Jakiro and Queen of Pain.
Queen of Pain
* Heroes with mobility spells like Queen of Pain, Anti-Mage, Phantom Assassin, Riki, Puck, and Spirit Breaker that are cancelled by Frostbite can suffer greatly from the presence of Crystal Maiden. It is absolutely critical, however, to have followup from teammates, as all of the above heroes can make quick work of the squishy Crystal Maiden after they are released from her grip.
Mirana
* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If 
Frostbite has already been used, Mirana can Leap away even when slowed by 
Crystal Nova or Freezing Field.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Queen of Pain
* All of Queen of Pain's abilities are active, making Demonic Purge break from Aghanim's Scepter useless.
* However, Demonic Purge can help his allies kill a squishy Queen of Pain.
* Blink allows Queen of Pain to escape from Shadow Demon's abilities if he doesn't have disables.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Sonic Wave for the enemy.
Mirana
* 
Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* 
Shackleshot through tree with 
Focus Fire via Aghanim's Scepter combo can kill Mirana quickly, before using Leap or Moonlight Shadow.
Queen of Pain
* Queen of Pain, for the most part, almost exclusively deals magical damage, ignoring Windranger's evasion from Windrun.
* Queen of Pain is also a common wielder of Orchid Malevolence, preventing Windranger from using her abilities for a while.
* Blink, when used correctly, allows Queen of Pain to dodge 
Powershot and Shackleshot.
Queen of Pain
* Ghostship helps your team soak up damage from Sonic Wave and Scream of Pain.
* Queen of Pain can't escape easily from X Marks the Spot - Torrent combo.
* Outlanes Queen of Pain on the midline, due to the fact that Queen of Pain has a small reserve of health at the beginning of the game, and she suffers very much from 
Tidebringer, which is why she is forced to either spend money on 
Tango, or skip creeps and run for bounty runes, and Kunkka at this time will gain an advantage in level and gold.
Additional:
* Outlanes Queen of Pain on the midline, due to the fact that Queen of Pain has a small reserve of health at the beginning of the game, and she suffers very much from Tidebringer, which is why she is forced to either spend money on Tango, or skip creeps and run for bounty runes, and Kunkka at this time will gain an advantage in level and gold.
* Kunkka will catch her in X Marks the Spot and allow his team to kill her for stun from Torrent, because Queen of Pain has no way to avoid the cross X Marks the Spot before buying Black King Bar.
Mirana
* Leap allows Mirana to easily escape Torrent and Ghostship.
Mirana
* Low-health, normally mobile carries who rely entirely on raw attack damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, 
Terrorblade, 
Troll Warlord, Weaver.
Queen of Pain
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: 
Disruptor, Death Prophet, Enigma, Faceless Void, 
Invoker, 
Lich, Magnus, Mars, Medusa, Outworld Destroyer, Phoenix, Puck, Queen of Pain, Shadow Fiend, 
Treant Protector, 
Underlord, Winter Wyvern, Witch Doctor, Zeus.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Queen of Pain
* Heroes who commonly buy Linken's Sphere: Luna, Weaver, Morphling, Queen of Pain, Ember Spirit.
Queen of Pain
* Shadow Shaman has many disables to lock down Queen of Pain, preventing her from Blinking away, even through Linken's Sphere or her spell block talent.
* 
Mass Serpent Ward can tear through Queen of Pain's low health pool once she's locked down by 
Hex & Shackles.
Mirana
* Mirana can disturb Shadow Shaman's channeling even if he is under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying towards Shadow Shaman can continue for the whole match.
Mirana
* Arc Warden can use his summons to prevent
Sacred Arrow from hitting himself or his allies.
Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Additional:
*
* Arc Warden can place
Queen of Pain
* Sonic Wave is a bad choice in abilities if he and the
Tempest Double both use 
Blade Mail to reflect the damage to Queen of Pain, potentially killing her outright if her health is low enough.
Magnetic Field protects himself or his ally from Queen of Pain's attacks unless she has 
Monkey King Bar.
Tempest Double is that he can deny himself if he is close to death with Shadow Strike's debuff.
*
* One more advantage of