Mirana
* Heroes with spells that negate invisibility such as 
Bounty Hunter, 
Zeus and 
Slardar prevent her from saving her allies with Moonlight Shadow.
Sand King
* Zeus usually stays at the back in teamfights and it is hard for Sand King to find Zeus and knock him down before Zeus deals his damage.
* All of Zeus' abilities, especially 
Thundergod's Wrath, disables Sand King's 
Blink Dagger, effectively reducing Sand King's initiation and counter-initiation potential.
* 
Lightning Bolt deals damage to Sand King in Sand Storm and reveals him. It also interrupts channeling of Epicenter.
Mirana
* Abaddon can remove Sacred Arrow's stun from his teammates with 
Aphotic Shield, or remove it from himself with 
Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's 
Aghanim's Scepter combo.
Additional:
* 
Sacred Arrow can be instantly dispelled by Aphotic Shield.
Mirana
* 
Track detects Mirana and her allies during Moonlight Shadow.
Mirana
* 
Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place 
Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
Additional:
* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Mirana
* Thirst detects Mirana or her ally at low health during 
Moonlight Shadow.
* Rupture deals high damage when Mirana uses 
Leap.
Additional:
* 
Rupture can quickly kill Mirana if she tries to Leap away.
* 
Thirst detects Mirana and her allies during Moonlight Shadow.
Mirana
* Mirana's Leap is ineffective if Lycan uses 
Shapeshift. It also allows him to dodge Sacred Arrow.
Sand King
* 
Boulder Smash will push Sand King out of Sand Storm to reveal his position or an activated Epicenter off of Earth Spirit's allies, potentially wasting his combo
* 
Rolling Boulder and 
Geomagnetic Grip allow Earth Spirit to easily stun and silence Sand King and interrupt the channeling of Epicenter, completely ruining his initiation.
Mirana
* 
Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* 
Shackleshot through tree with 
Focus Fire via Aghanim's Scepter combo can kill Mirana quickly, before using Leap or Moonlight Shadow.
Sand King
* Sand King has nothing to deal with 
Supernova, as none of his spells are effective.
* The damage-over-time abilities of Phoenix disable Sand King's Blink Dagger very often.
Sand King
* 
Ravage, being an AoE disable, cancels Epicenter's channeling from a long range, limiting his potential to counter-initiate.
* This can be remedied, however, by first using a 
Black King Bar, then channel Epicenter, then finally initiate with Blink Dagger.
Mirana
* Puck can initiate on Mirana with 
Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in 
Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with 
Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid 
Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.
Mirana
* 
Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and 
Light Strike Array can disable Mirana if she tries to Leap away.
* 
Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.
Additional:
* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Sand King
* Burrowstrike is one of the best and easiest steals for Rubick and Sand King should be careful when playing against him - it's much better to give away Sand Storm.
Sand King
* Quill Spray will hit Sand King inside 
Sand Storm, damaging him and putting Sand King's Blink Dagger on cooldown, preventing him from escaping.
* 
Epicenter's numerous damage ticks will trigger Bristleback's passive repeatedly during teamfights.
Mirana
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, 
Outworld Destroyer, 
Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like 
Storm Spirit, 
Mirana, 
Anti-Mage and others won't be able to do much if they're caught.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, 
Phantom Lancer, 
Nature's Prophet.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, 
Queen of Pain, Storm Spirit, 
Riki.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.
Mirana
* If Slark sees the Sacred Arrow before it hits him, he can use 
Dark Pact to remove it a moment later.
* 
Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter combo with 
Shadow Dance.
Sand King
* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, 
Earth Spirit, 
Faceless Void, 
Magnus, Mirana, 
Monkey King, 
Morphling, 
Pangolier, 
Phantom Assassin, 
Phoenix, 
Puck, Queen of Pain, Riki, 
Sand King, 
Spirit Breaker, 
Timbersaw, 
Tusk.
Sand King
* Slark will have a hard time killing Sand King because of the survivability he gets from Burrowstrike and Sand Storm.
* Shadow Dance, which usually allows Slark to survive fights, is ineffective against Sand King's AoE damage.
Mirana
* Heroes who rely on invisibility, such as Bounty Hunter, 
Clinkz, Mirana, 
Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Mirana
* Heroes with silences and hard stuns such as 
Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Additional:
* 
Doom completely takes Mirana out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Mirana
* The long silence of 
Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With 
Dark Ascension and 
Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Sand King
* Heroes that rely on slows to get kills: 
Lifestealer, 
Night Stalker, 
Ursa, Phantom Assassin, 
Terrorblade.
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of 
Chen or 
Enchantress.
Sand King
* 
Burrowstrike, Sand Storm, 
Caustic Finale and Epicenter will deal a large amount of damage to Chen and his creeps.
Mirana
* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys 
Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and 
Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.
Mirana
* Techies spends lots of time standing still planting stacks of 
Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use 
Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.
Sand King
* Sand King can quickly remove her 
Refraction with his Sand Storm.
* Once Refraction is down, she is very vulnerable to Epicenter's high magic damage.
Mirana
* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If 
Frostbite has already been used, Mirana can Leap away even when slowed by 
Crystal Nova or 
Freezing Field.
Sand King
* Phantom Assassin relies on her 
Blur to stay alive, but is very vulnerable to Sand King's heavy magic damage.
* With Burrowstrike, Sand King can often catch Phantom Assassin before she can use her Black King Bar.
* Sand King can dodge 
Stifling Dagger with Sandstorm.
* Phantom Assassin has a hard time killing Sand King because of his high mobility.
Mirana
* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* 
Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
Mirana
* Mirana can use Leap to jump right next to Drow Ranger or can approach her while under cover of the invisibility granted by Moonlight Shadow, which cancels the bonus granted to Drow Ranger by 
Marksmanship.
* Her low health makes her easy to burst down with Mirana's spells, especially with Aghanim's Scepter.
* Mirana can dodge 
Gust with good reaction time, or Leap away if Drow tries to slow her without Gust.
Mirana
* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build 
Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.
Mirana
* Mirana can disturb Shadow Shaman's channeling even if he is under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying towards Shadow Shaman can continue for the whole match.
Sand King
* Sand King's Sand Storm damages familiars quickly whittling them down in health, rendering them vulnerable.
* Sand King's Epicenter quickly damages and destroys familiars.
Mirana
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, Faceless Void, Magnus
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or Enchantress.
Sand King
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: Phantom Assassin, Clinkz, 
Sniper, Enchantress.
Sand King
* Heroes that rely on slows to get kills: Lifestealer, Night Stalker, Ursa, Phantom Assassin, Terrorblade.
Sand King
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: Phantom Assassin, Clinkz, Sniper, Enchantress.
Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: 
Dragon Knight, 
Jakiro, 
Pugna, 
Earthshaker.
Sand King
* Because of his massive AoE damage, Sand King is very effective against illusion heroes: 
Chaos Knight, Phantom Lancer, Terrorblade, 
Naga Siren.
Additional:
* Sand King's massive area damage output, particularly Epicenter, allows him to quickly take down Chaos Knight and his illusions.
* Sand King can also apply Caustic Finale to illusions with attacks for extra damage when they die.
Sand King
* Because of his massive AoE damage, Sand King is very effective against illusion heroes: Chaos Knight, Phantom Lancer, Terrorblade, Naga Siren.
Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, Earthshaker.
Mirana
* Heroes that cannot move in fights such as a 
Dueling Legion Commander or anyone channeling a spell like 
Bane, 
Pudge, or 
Enigma are easy Sacred Arrow targets.
Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates difficult targets to hook.
* Sacred Arrow can be used to cancel Dismember from long distances.
Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, Earthshaker.
Sand King
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: 
Sven, 
Omniknight, Enigma, 
Luna, Naga Siren, 
Mars, Jakiro, 
Venomancer, 
Elder Titan, Faceless Void, 
Rubick, 
Keeper of the Light, Pugna, 
Invoker, 
Spectre, 
Alchemist, 
Treant Protector, 
Lina, Oracle, Zeus, 
Shadow Shaman, Phoenix, 
Razor, 
Huskar, 
Batrider, 
Kunkka, 
Tidehunter, 
Wraith King, Sand King, 
Medusa, 
Dawnbreaker.
Mirana
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: 
Arc Warden, Chen, Clinkz, 
Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Sand King
* Sand King is a strong ganker, allowing him to shut down squishy heroes in the early game: Phantom Assassin, Clinkz, Sniper, Enchantress.
Mirana
* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Sand King
* Heroes that rely on slows to get kills: Lifestealer, Night Stalker, Ursa, Phantom Assassin, Terrorblade.
Sand King
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, 
Viper, Venomancer, Huskar, 
Ember Spirit, 
Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Mirana
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from 
Eclipse with Moonlight Shadow, smart Luna can buy 
Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Mirana
* A couple of long-range heroes with excellent laning like Mirana, Lina, 
Necrophos, 
Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Sand King
* Burrowstrike allows Sand King to escape from Eclipse or to close the gap on Luna and finish her off.
* Sand Storm allows Sand King to harass Luna more efficiently than she does with 
Lucent Beam, as it makes him invisible for it's duration and while in it, rendering him safe from both, Lucent Beam and Eclipse and forcing Luna to buy Dust of Appearance more often.
* Caustic Finale allows Sand King to deal serious damage to both, Luna and her allies, which is especially hazardous for Luna during the laning stage as Luna's attack range is short.
* Epicenter combined with Burrowstrike and Sand Storm can often kill Luna before she can do anything because of her low health and strength gain.
* Overall, Sand King forces Luna to play more defensively instead of offensively, and for the same reasons, Sand King makes a very powerful ally for Luna when they are in the same team.
Additional:
* Burrowstrike allows Sand King to escape from Eclipse or to close the gap on Luna and finish her off.
* Sand Storm allows Sand King to harass Luna more efficiently than she does with Lucent Beam, as it makes him invisible for it's duration and while in it, rendering him safe from both, Lucent Beam and Eclipse and forcing Luna to buy Dust of Appearance more often.
* Caustic Finale allows Sand King to deal serious damage to both, Luna and her allies, which is especially hazardous in laning stage as Luna's attack range is short.
* Epicenter combined with Burrowstrike and Sand Storm can often kill Luna before she can do anything because of her low health and strength gain.
* Overall, Sand King forces Luna to play more defensively instead of offensively, and for the same reasons, Sand King makes a very powerful ally for Luna when they are in the same team.
Sand King
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's 
Solar Guardian, 
Axe's 
Berserker's Call, Mars's 
Arena of Blood, Jakiro's 
Macropyre, 
Dual Breath and 
Ice Path, Naga Siren's 
Song of the Siren, Razor's 
Eye of the Storm and 
Plasma Field, Lina's Light Strike Array, 
Broodmother's 
Spinner's Snare from Aghanim's Scepter, Elder Titan's 
Earth Splitter and 
Echo Stomp, Alchemist's 
Unstable Concoction and 
Acid Spray, Queen of Pain's 
Sonic Wave, Dark Seer's 
Wall of Replica and 
Vacuum, Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from 
Aghanim's Shard, 
Bloodseeker's 
Blood Rite, Enigma's 
Black Hole and 
Midnight Pulse, 
Shadow Fiend's 
Requiem of Souls, Batrider's Aghanim's Scepter upgraded 
Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, 
Ancient Apparition's 
Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, 
Gyrocopter's 
Call Down, Ember Spirit's 
Sleight of Fist, Death Prophet's 
Exorcism and 
Silence, Monkey King's 
Wukong's Command, 
Crystal Maiden's Freezing Field, 
Muerta's 
The Calling, Medusa's 
Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, Pangolier's 
Swashbuckle, 
Grimstroke's 
Soulbind, 
Ink Swell and 
Stroke of Fate, Earthshaker's 
Echo Slam and 
Fissure, Puck's Dream Coil and Waning Rift, 
Winter Wyvern's 
Winter's Curse, Magnus's 
Reverse Polarity.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Sand King
* All of Sand King's abilities deal AoE damage.
* However, Epicenter is usually a non-issue against Doppelganger.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Sand King
* With Caustic Finale, Sand King can easily kill the treants from 
Nature's Call.
* Burrowstrike allows Sand King to prevent Nature's Prophet from using 
Teleportation inside of his 
Sprout.
Additional:
* Sand King's Caustic Finale combined with Sand Storm will kill Treants easily.
* Sand King can interrupt Teleportation with Burrowstrike, even through Sprout.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Counterspell does not protect Anti-Mage from Sacred Arrow.
* Moonlight Shadow can help her allies avoid Mana Break and Mana Void.
* Blink's cooldown isn't short enough to escape from Leap, especially when she has the extra charge from Aghanim's Shard.
Additional:
* Combo items for Mirana 
Rod of Atos can upgrade to 
Gleipnir and Sacred Arrow before and during Anti-Mage build item Manta Style cooldown can easy penetrates Counterspell broken.
* Charge for Leap can Mirana easily faster escaping.
* Moonlight Shadow it can disappear anytime and Anti-Mage can not fight.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Mirana
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or 
Leshrac's 
Split Earth, or combos like Kunkka's 
X Marks the Spot into 
Torrent.
Sand King
* Pugna's 
Nether Ward damages Sand King when he channels Epicenter, preventing him from using Blink Dagger afterward.
Sand King
* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, Earthshaker.
Mirana
* 
Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by 
Poof and 
Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Sand King
* Burrowstrike can stun multiple Meepos, making them vulnerable targets.
* Epicenter and Sand Storm's AoE damage ensures all Meepo clones get damaged, making it hard for Meepo to choose which one to flee as all are taking damage at the same rate.
* Just be aware when using Sand Storm to escape, as Meepo has good AoE damage and disables, which, as explained in the "Bad Against" section, works well against an invisible Sand King.
Mirana
* Low-health, normally mobile carries who rely entirely on raw attack damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, 
Juggernaut, 
Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, 
Slark, Sniper, Terrorblade, 
Troll Warlord, 
Weaver.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Sand King
* Ghostship helps your team soak up damage from Epicenter, especially if he initiates during the battle.
* Sand King can't dodge X Marks the Spot - Torrent combo by his abilities. Torrent drags him out of his Sand Storm
Mirana
* Leap allows Mirana to easily escape Torrent and Ghostship.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Mirana
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from 
Spawn Spiderlings, which in combination with the huge speed provided by 
Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys 
Orchid Malevolence and it's upgrade 
Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, and prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Sand King
* Caustic Finale allows Sand King to easily kill Broodmother's Spiderlings throughout the game.
* Sand King can usually catch a split pushing Broodmother with Blink Dagger and Burrowstrike.
Additional:
* Burrowstrike can be used as an escape or initiation against Broodmother.
* Sand Storm quickly kills any spiderlings caught inside if Sand King can manage to stun them.
Sand King
* Lifestealer's Rage negates Sand King's spells which do magical damage.
Sand King
* Heroes that rely on slows to get kills: Lifestealer, Night Stalker, Ursa, Phantom Assassin, Terrorblade.
Mirana
* Heroes with silences and hard stuns such as
Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Sand King
* Both
Arcane Curse and 
Last Word punishes casters with spammable spells such as Sand King.
Intelligence Steal reduces Sand King's mana pool even more.
Global Silence silences Sand King, effectively reducing Sand King's initiation and counter-initiation potential. It can also interrupt channeling of Epicenter.
* As a strength caster,
*