* Thirst detects Mirana or her ally at low health during Moonlight Shadow.
* Rupture deals high damage when Mirana uses Leap.
Additional:
* Rupture can quickly kill Mirana if she tries to Leap away.
* Thirst detects Mirana and her allies during Moonlight Shadow.

* Rupture and Blood Rite locks down Timbersaw, preventing him from escaping with Timber Chain. However, Timbersaw may reflect a good deal of damage with Blade Mail.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Timbersaw is heavily reliant on his abilities for damage and escape, allowing Silencer to effectively disable him and make him useless in both team fights and 1v1 scenarios.
Additional:
* Arcane Curse deals repeated stacks of damage to Timbersaw because he relies on constantly using his abilities.
* Glaives of Wisdom deals pure damage and when cast manually, nearby creeps will not attack silencer, making it an effective harassment tool.
* Although Last Word takes a while to trigger, it will break Timbersaw's ability combo and can be used to silence him.
* Global Silence will silence Timberaw no matter where he is on the map. This can be used to help allies get a kill on him, or prevent Timbersaw from killing someone.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Arcane Orb's pure damage ignores Timbersaw's Reactive Armor.
* Astral Imprisonment, if timed correctly, can interrupt Timber Chain, preventing him from escaping.
Additional:
* Arcane Orb deals constant pure damage, which bypasses Timbersaw's Reactive Armor.
* Sanity's Eclipse can hit targets inside Astral Imprisonment, which helps Outworld Destroyer finish off Timbersaw before he escapes with Timber Chain. It can also drain his mana, limiting his ability to escape should he survive.

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* Zeus deals enormous amounts of magic damage, being one of the best heroes to burst down Timbersaw early in the game.
* Lightning Bolt's mini-stun can stop Timbersaw's from escaping a fight with Timber Chain.
* Timbersaws tend to build health increasing items, making Zeus' Static Field deal huge amounts of damage.
Additional:
* Reactive Armor will not trigger from Zeus's spells or protect Timbersaw from their damage.
* Early game Timbersaw's strength is average and Zeus can heavily aid in bursting him down.
* Late game, if Timbersaw has built a lot of HP items, Zeus's passive Static Field will be more effective at chipping away Timbersaw's large HP pool.
* A Timbersaw who builds Pipe of Insight will be much more difficult to kill, as Zeus has no way to hold Timbersaw down, but Timbersaw will have less armor, mana, and damage than normal if he buys this item early game just to counter Zeus.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Ball Lightning makes Storm Spirit a target difficult to chase, even for a hero as mobile as Timbersaw.
* The magical damage from Static Remnant and Overload together with Storm Spirit's high mobility allows Storm Spirit to jump on Timbersaw and burst him down, even if he tries to escape.

* Puck can initiate on Mirana with Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.

* Any Hero with high mobility will be neutralized by dream coil: Queen of Pain, Storm Spirit, Ember Spirit, Lycan, Bloodseeker, Anti-Mage, Timbersaw

* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.

* Time Dilation is similar to a long duration silence, making Timbersaw useless in team fights, or forcing him to adapt his build.
* Time Walk negates Timbersaw's burst damage.
* Time Lock provides magical damage and lock down, and is effective against both Reactive Armor and Timber Chain.
* In conjunction with Time Lock's magical damage, Chronosphere can destroy Timbersaw before he has time to react, and creates a large obstacle that obstruct's Timber Chain's mobility.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Infernal Blade deals scaling damage and is useful against high HP targets such as Timbersaw.
* Timbersaw is extremely reliant on his abilities to be effective during a team fight - both for mobility, damage and crowd control. Timbersaw offers very little impactful right-click damage, and thus Doom is particularly crippling against this hero.
* Additionally, when upgraded with Aghanim's Scepter, Doom breaks Reactive Armor, which effectively removes the durability which Timbersaw is commonly known for.
Additional:
* Doom shuts down Timbersaw completely, negating his mobility and preventing him from doing any damage. It also breaks Reactive Armor's passive bonuses from Aghanim's Scepter.
* Infernal Blade can stun Timbersaw several times in a fight, potentially interrupting Timber Chain. Also it's useful since Timbersaw has high HP due to the damage scales based on max HP.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes who build mana boosting items but have low mana regeneration are especially vulnerable against Mana Break and Mana Void: Timbersaw, Slark, Shadow Fiend, Clinkz, Bristleback Nyx Assassin, Magnus

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain

* Because Timbersaw relies heavily on his spells to deal damage, Silence can easily disable him in a team fight.
* Exorcism's spirits do not count as regular attacks, and will not add stacks of Reactive Armor.

* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Additional:
* Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.

* Timbersaw's physical survivability revolves around Reactive Armor, which is largely ignored by Fury Swipes due to the extreme amounts of damage it does in a very few number of attacks.
* Timbersaw's burst damage will not do much against Enrage, although he could easily use Timber Chain to escape, wasting the duration of it.

* The long silence of Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With Dark Ascension and Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.

* If Slark sees the Sacred Arrow before it hits him, he can use Dark Pact to remove it a moment later.
* Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's Aghanim's Scepter​ combo with Shadow Dance.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Track detects Mirana and her allies during Moonlight Shadow.

* Bramble Maze prevents Timbersaw from Timber Chaining away without getting rooted.
* Cursed Crown can still catch Timbersaw if he Timber Chains away.
* Reactive Armor offers little protection against Dark Willow's high magical damage.

* Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with Aphotic Shield, or remove it from himself with Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.

* Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with Moonlight Shadow.
Additional:
* Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and Light Strike Array can disable Mirana if she tries to Leap away.
* Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.

* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain

* Magical burst damage is Timbersaw's weakness, and Ancient Seal not only amplifies it but also prevents him from using Timber Chain to escape for up to 6 seconds.
* He generally doesn't build early items to deal with silences.
* Reactive Armor does not trigger on magic damage or spells, meaning that even a Pipe of Insight won't give him the massive sustain he normally gets from attacks.
Additional:
* Skywrath Mage's long range and low cooldown magic damage spells can easily harass Timbersaw out of lane.
* Ancient Seal is not only a long lasting silence, (one of Timbersaw's biggest weaknesses) but it also makes him even more vulnerable to magical burst damage.

* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.

* Heroes who are melee but cannot fight back against Eclipse will really struggle with Luna: Monkey King, Alchemist, Timbersaw.

* Nethertoxin prevents Timbersaw from gaining stacks on Reactive Armor.

* Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* Shackleshot through tree with Focus Fire via Aghanim's Scepter​ combo can kill Mirana quickly, before using Leap or Moonlight Shadow.

* Searing Chains prevents usage of Timber Chain.
* Timbersaw is vulnerable to magical burst damage, which Ember Spirit provides with Fire Remnant and Flame Guard.
* Timbersaw's abilities deal pure damage, thus they cannot remove Flame Guard.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Brain Sap's pure damage ignores stacks of Reactive Armor.
* Nightmare prevents Timbersaw from using Timber Chain, setting him up for chain stuns and burst damage.
* Enfeeble highly reduces regeneration granted by reactive armor.
* Fiend's Grip immobilizes Timbersaw and drains his low mana pool, preventing escape afterwards. It also pierces Black King Bar.
* Bane's multiple disables often force Timbersaw or his teammates to spend gold on a Linken's Sphere.

* Cold Snap can prevent Timbersaw from using both Timber Chain and Chakram due to the frequent stuns interrupting the lengthy cast animations, as well as stopping him mid-chain. This can negate Timbersaw's attempts to escape or dole out extra ability damage.
* Later in the game, Invoker's heavy magical and pure damage can be difficult to avoid, meaning Timbersaw's armor is less useful.

* Rolling Thunder's stuns make it harder for Timbersaw to escape with Timber Chain.

* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw.
* Decrepify can further increase all the magical damage done to Timbersaw, bypassing the enhanced physical resistance he can get from Reactive Armor.
Additional:
* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw, especially when combined with Decrepify

* Timbersaw relies heavily on his abilities so Phantom's Embrace's silence makes it more difficult for him.
* Timbersaw cannot use Return Chakram or attack the phantom during Phantom's Embrace, forcing him to take full damage and refreshes Phantom's Embrace's cooldown.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Hex greatly reduces Timbersaw's mobility.
* In addition, Lion can follow up with his Earth Spike and Mana Drain combo, preventing Timbersaw to escape with Timber Chain. And he can finish Timbersaw off with Finger of Death if the latter's HP is low enough.

* Reactive Armor's armor increase does not affects Muerta's Pierce the Veil despite Muerta often building high attack speed.
* Muerta's Dead Shot destroys trees preventing Timbersaw from escaping with his Timber Chain

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.

* In general, Timbersaw struggles against highly mobile heroes that can avoid his abilities: Puck, Weaver, Ember Spirit and others.

* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like Rod of Atos or Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.

Additional:
* Heartstopper Aura effectively negates Timbersaw's large HP pool as well as HP regen.
* Death Pulse together with health and mana regeneration from killed creeps helps Necrophos and his teammates survive Timbersaw's burst damage.
* As a tanky hero that stays in the middle of teamfights, Timbersaw is an easy target for Reaper's Scythe.

* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain

* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki

* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.

* All Tinker's damage is magic/pure and completely ignores Timbersaw's Reactive Armor.
* Timbersaw very rarely builds Black King Bar, making him very vulnerable if Tinker builds Scythe of Vyse.