Mirana
* If Slark sees the Sacred Arrow before it hits him, he can use 
Dark Pact to remove it a moment later.
* 
Pounce prevents Mirana from escaping with Leap.
* Slark can survive Mirana's 
Aghanim's Scepter combo with 
Shadow Dance.
Venomancer
* Dark Pact can dispel Venomous Gale and Poison Sting.
* Shadow Dance allows Slark heightened regeneration when out of vision making DoTs effects less threatening.
Mirana
* 
Sacred Arrow can be instantly dispelled by Aphotic Shield.
Additional:
* Abaddon can remove Sacred Arrow's stun from his teammates with 
Aphotic Shield, or remove it from himself with 
Borrowed Time.
* Borrowed Time makes Abaddon almost impossible to burst down with Mirana's Aghanim's Scepter combo.
Venomancer
* Heroes that deal damage over time will also fail to bring down Abaddon and his allies, such as 
Huskar, 
Venomancer, or 
Phoenix.
Additional:
* Borrowed Time & Aphotic Shield can dispel Venomous Gale and Poison Sting.
Mirana
* Arc Warden can use his summons to prevent Sacred Arrow from hitting himself or his allies.
* Mirana doesn't build items that give armor often, so she usually can't fight against a late game Arc Warden.
Additional:
* 
Flux will slow and damage Mirana even after she Leaps, since she will likely not be near allies.
* Arc Warden can place 
Magnetic Field on an ally who has been hit by Sacred Arrow to protect them.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: 
Arc Warden, 
Chen, 
Clinkz, 
Drow Ranger, 
Lina, 
Mirana, 
Nature's Prophet, 
Pugna and 
Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: 
Shadow Demon, 
Phantom Lancer, Nature's Prophet.
Venomancer
* In the laning stage, making illusions of Venomancer will turn his 
Poison Sting back at him, making for an easy gank at level one, and for later when your mid comes for ganks.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Venomancer
* Teleportation allows Natures Prophet to save himself from the damage over time of 
Venomous Gale, Poison Sting and 
Poison Nova.
* 
Plague Wards can be destroyed with Nature's Prophet's Treants.
Mirana
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, 
Outworld Destroyer, Shadow Demon and 
Oracle can reduce the effectiveness of Sacred Arrow.
Venomancer
* Fortune's End and False Promise easily dispel many crippling debuffs, such as Venomancer's Venomous Gale, or 
Skywrath Mage's 
Ancient Seal.
Additional:
* 
Fortune's End can dispel Venomous Gale and Poison Sting from allies.
* 
Fate's Edict grants 100% magic resistance to target, inhibiting the damage from Venomancer abilities.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: 
Anti-Mage, 
Queen of Pain, 
Storm Spirit, 
Riki.
Venomancer
* Squishy heroes or heroes without hard disables or silences: Shadow Demon, 
Shadow Fiend, Venomancer, 
Ancient Apparition etc.
Mirana
* Heroes with spells that negate invisibility such as 
Bounty Hunter, 
Zeus and 
Slardar prevent her from saving her allies with Moonlight Shadow.
Venomancer
* Slardar can attack through Plague Wards and gain 
Bash of the Deep charges, and 
Templar Assassin can spill 
Psi Blades through Plague Wards too.
Mirana
* The long silence of 
Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With 
Dark Ascension and 
Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Venomancer
* While 
Reincarnation is off cooldown, Poison Nova poses less of a threat as Wraith King will return with all debuffs cleared.
* 
Vampiric Spirit can out-heal the slow {tooltip:DoT|Damage over Time} from Poison Sting.
Mirana
* Though Mirana can clear waves of Broodmother's spiderlings with 
Starstorm, Broodmother will often stick with her spiderlings from 
Spawn Spiderlings, which in combination with the huge speed provided by 
Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys 
Orchid Malevolence and it's upgrade 
Bloodthorn, which allows her to prevent Mirana from escaping with both, 
Leap and 
Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to 
Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, and prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Additional:
* Though Mirana can clear waves of Broodmother's spiderlings with Starstorm, Broodmother will often stick with her spiderlings from Spawn Spiderlings, which in combination with the huge speed provided by Spin Web can make it hard for Mirana to hit her with Sacred Arrow.
* Broodmother commonly buys Orchid Malevolence and it's upgrade Bloodthorn, which allows her to prevent Mirana from escaping with both, Leap and Moonlight Shadow and from fighting back with Starstorm.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Mirana, deal damage over time to Mirana and reveal Mirana if she or any of her allies unwittingly step on them while affected by Moonlight Shadow, disrupting her attempts to initiate with Moonlight Shadow and Sacred Arrow, prevent her to use Leap while also alerting Broodmother on her attempts to ambush her and her allies.
Venomancer
* Venomancer is a low health hero and low range hero who is easy to harass with Ion Shell on a creep in the early game.
* Venomancer depends entirely on all his slows to keep distance or chase, but since Surge ignores slows, it is nearly impossible for Venomancer to hunt or run away from Dark Seer or his surged teammates.
Mirana
* Thirst detects Mirana or her ally at low health during Moonlight Shadow.
* Rupture deals high damage when Mirana uses Leap.
Additional:
* 
Rupture can quickly kill Mirana if she tries to Leap away.
* 
Thirst detects Mirana and her allies during Moonlight Shadow.
Venomancer
* 
Corrosive Skin means Viper can often outlast Venomancer in a battle of attrition.
* Venomancer has no mobility without items, which makes him vulnerable to constant slows.
Venomancer
* Venomous Gale is a great ganking and farming skill.
* Plague Ward serves as a flexible ability for pushing, ganking, farming and scouting. The innate Poison Sting also works on the stolen Plague Ward with half the damage.
* Poison Nova, if stolen and cast, puts a huge damage-over-time debuff on the enemy team, even greater than Venomancer himself with the help of 
Arcane Supremacy.
* 
Spell Steal has a greater cast distance than the effect area of Poison Nova, allowing Rubick to steal the spell while staying at the back.
* Venomancer suffers from mana pool problems, while Rubick has relatively high intelligence gain and can cast the same set of spells at ease.
Additional:
* All of Venomancer's abilities are decent choices for Rubick's Spell Steal. Stealing Plague Wards makes them apply Poison Sting as well.
Mirana
* Mirana's Leap is ineffective if Lycan uses 
Shapeshift. It also allows him to dodge Sacred Arrow.
Venomancer
* Venomancer's damage-over-time abilities are easier to heal through with numerous Shadow Waves than other types of damage, and it's simple to time a Shallow Grave until the last possible second to save a teammate from them.
Venomancer
* Sniper can easily destroy Plague Ward from long range.
Venomancer
* Snowball can be used to save allies or himself during Venomous Gale and Poison Nova.
* Venomancer lacks mobility and has low base health, so he can be killed by Walrus PUNCH!
Mirana
* 
Doom completely takes Mirana out of a team fight, a hero who relies heavily on using abilities and items to contribute in team fights.
Mirana
* Overgrowth has a great duration, which prevents the units caught from attacking, moving and Blinking. Heroes like Storm Spirit, Mirana, Anti-Mage and others won't be able to do much if they're caught.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Venomancer
* Heroes rely on their debuff to control the opponent will have a hard time against Press the Attack: Venomancer, 
Earth Spirit, 
Ogre Magi
Additional:
* 
Press the Attack dispels Venomous Gale and Poison Sting from Legion Commander or her teammates.
* Venomancer is an ideal target for 
Duel due to his lack of mobility and low starting health.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like 
Bane, 
Pudge, or 
Enigma are easy Sacred Arrow targets.
Mirana
* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Heroes with silences and hard stuns such as 
Doom, 
Silencer, and 
Lion can keep Mirana from Leaping away.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, 
Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Mirana
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Venomancer
* Venomancer's damage-over-time abilities do little damage against Counterspell.
* Blink helps Anti-Mage get away from Venomancer's slows.
Additional:
* 
Counterspell provides magic resistance, diminishing the effectiveness of Venomancer's spells.
* Venomancer's lack of hard disable allows Anti-Mage to use 
Blink, circumventing the slows Venomancer depends on.
Mirana
* Counterspell does not protect Anti-Mage from Sacred Arrow.
* Moonlight Shadow can help her allies avoid Mana Break and Mana Void.
* Blink's cooldown isn't short enough to escape from Leap, especially when she has the extra charge from 
Aghanim's Shard.
Additional:
* Combo items for Mirana 
Rod of Atos can upgrade to 
Gleipnir and Sacred Arrow before and during Anti-Mage build item 
Manta Style cooldown can easy penetrates Counterspell broken.
* Charge for Leap can Mirana easily faster escaping.
* Moonlight Shadow it can disappear anytime and Anti-Mage can not fight.
Venomancer
* Vulnerable spellcasters with no escape mechanisms are easy targets for Huskar: 
Lich, 
Crystal Maiden, Silencer, 
Keeper of the Light, Venomancer, etc.
Additional:
* Huskar can easily regenerate lost health from DoT spells through 
Berserker's Blood rendering them ineffective
* Venomancer has little armor and mobility, and rarely builds Linken's Sphere, so he is quite vulnerable to 
Life Break.
Mirana
* Heroes with spells that negate invisibility such as Bounty Hunter, Zeus and Slardar prevent her from saving her allies with Moonlight Shadow.
Venomancer
* Heroes with damage-over-time abilities easily allow Bristleback to turn his back in order to proc 
Bristleback continuously and to massively reduce to damage dealt to him: Arc Warden, Venomancer, 
Luna.
Venomancer
* Sunder can prevent Terrorblade's or an ally's death by swapping health, making damage-over-time abilities inefficient. Heroes that rely on damage-over-time abilities like Venomancer and Huskar will have a hard time against Sunder.
Additional:
* 
Reflection illusion will apply Poison Sting back towards Venomancer.
* 
Conjure Image and 
Metamorphosis will make quick work of Plague Wards.
* While ticking down from Poison Nova, Terrorblade can wait until the last possible moment to 
Sunder a target, either friend or foe.
Mirana
* Heroes with summons or illusions makes Sacred Arrow harder to land: Shadow Demon, Phantom Lancer, Nature's Prophet.
Venomancer
* 
Dark Rift allows Underlord to transport allies from poison damage-over-time to the fountain.
* Underlord usually buys 
Pipe of Insight that gives a magic resistance to allies, inhibiting the damage from Venomancer abilities.
Venomancer
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded 
Eclipse, 
Dawnbreaker's 
Solar Guardian, 
Axe's 
Berserker's Call, 
Mars's 
Arena of Blood, 
Jakiro's 
Macropyre, 
Dual Breath and 
Ice Path, 
Naga Siren's 
Song of the Siren, 
Razor's 
Eye of the Storm and 
Plasma Field, Lina's 
Light Strike Array, 
Broodmother's Spinner's Snare from Aghanim's Scepter, 
Elder Titan's 
Earth Splitter and 
Echo Stomp, 
Alchemist's 
Unstable Concoction and 
Acid Spray, Queen of Pain's 
Sonic Wave, 
Dark Seer's 
Wall of Replica and 
Vacuum, Venomancer's 
Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and 
Rain of Destiny from Aghanim's Shard, 
Bloodseeker's 
Blood Rite, Enigma's 
Black Hole and 
Midnight Pulse, Shadow Fiend's 
Requiem of Souls, 
Batrider's Aghanim's Scepter upgraded 
Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, Ancient Apparition's 
Ice Blast, 
Sand King's 
Epicenter, 
Sand Storm and 
Burrowstrike, 
Gyrocopter's 
Call Down, 
Ember Spirit's 
Sleight of Fist, 
Death Prophet's 
Exorcism and 
Silence, 
Monkey King's 
Wukong's Command, Crystal Maiden's 
Freezing Field, 
Muerta's 
The Calling, 
Medusa's 
Stone Gaze, Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, 
Pangolier's 
Swashbuckle, 
Grimstroke's 
Soulbind, 
Ink Swell and 
Stroke of Fate, 
Earthshaker's 
Echo Slam and 
Fissure, 
Puck's 
Dream Coil and 
Waning Rift, 
Winter Wyvern's 
Winter's Curse, 
Magnus's 
Reverse Polarity.
Mirana
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy 
Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Additional:
* Even though Luna is the kind of hero that Mirana can handle due to Moonlight Shadow rendering her safe from Eclipse with Moonlight Shadow, smart Luna can buy Dust of Appearance, allowing her to provide vision on her to her team, and possibly, kill Mirana.
* Luna's high movement speed allows her to evade Sacred Arrow, giving Mirana difficulties in hitting her with it.
* Aghanim's Scepter upgraded Eclipse combined with Dust of Appearance allows Luna to cast it on a hero that is struck by Sacred Arrow and/or after Mirana jumps in with Leap.
Mirana
* A couple of long-range heroes with excellent laning like Mirana, Lina, 
Necrophos, Death Prophet. The key to success is sticking together and attacking Luna whenever she enters the range, without even giving Luna a chance to retaliate. Multiple long-range heroes is a reason to pick another hero.
Mirana
* Techies spends lots of time standing still planting stacks of 
Land Mines away from creep waves.
* Sacred Arrow can be used to scout hidden Land Mines among trees and at uphill places. It can also be used to catch Techies while he's planting them.
* If Techies is hit with a Sacred Arrow, he can be killed before he has a chance to use 
Blast Off!.
* Mirana has a high attack range to destroy his traps from a safe distance.
Venomancer
* Plague Wards may reveal a hiding Techies. If there's a sentry nearby, they may also reveal a stack of mines hidden in a juking spot.
Venomancer
* Plague Wards are very hard for Batrider to play against as they provide a lot of vision as well as disable 
Blink Dagger for a long duration.
Mirana
* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys 
Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and 
Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Heroes that can instantly kill creeps greatly reduce the effectiveness of Chen's converted army: 
Lifestealer, Doom, Mirana, Clinkz.
Venomancer
* Venomancer's damage over time can force Chen to use Hand of God prematurely, potentially wasting a chance to save his allies during a teamfight.
* Venomancer's Poison Nova, Venomous Gale and Plague Ward can easily kill Chen's creeps.
Venomancer
* Venomancer's magical damage-over-time poisons will constantly put Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Poison Nova will hit Monkey King when he is perched on a tree, or disguised with Mischief.
* However, Venomancer is also easily ganked by Monkey King if caught by surprise.
Additional:
* Venomancer's magical damage-over-time poisons putting 
Tree Dance on cooldown, greatly diminishing Monkey King's mobility.
* Venomous Gale and Posion Nova will hit Monkey King when he is perched on a tree, or disguised by 
Mischief.
Mirana
* Heroes that have an escape that doesn't disjoint projectiles: Mirana, 
Faceless Void, Magnus
Mirana
* Mirana can instantly kill creeps with Sacred Arrow, making her decent at crippling the armies of Chen or 
Enchantress.
Venomancer
* Untouchable won't mitigate Venomancer's magical damage, and Enchantress is vulnerable to magic damage.
* Both Venomous Gale and Poison Nova lower the amount of healing received by Enchantress and her allies from Nature's Attendants.
Venomancer
* Venomancer's spells all deal magical damage, ignoring Bulwark.
* Venomancer's multiple slows are especially effective at kiting Mars.
* Plague Ward can attack through Arena Of Blood.
Additional:
* Venomancer's poison attacks are all magical damage, ignoring 
Bulwark.
* Venomancer's multiple slows are especially effective against Mars' low mobility.
* Plague Wards can attack through Arena of Blood.
Venomancer
* Similar to Night Stalker, Venomancer can simultaneously scout Magnus hiding in trees and put Blink Dagger on cooldown with Plague Ward, which gives Magnus problems when trying to blink in and initiate.
Additional:
* Venomancer can simultaneously scout Magnus hiding in trees and putting Blink Dagger on cooldown with Plague Wards, which makes Magnus real problems to blink and initiate.
Venomancer
* Venomancer's poison damage over time is very effective against Spectre, who tends to lack magic resistance during the early to mid game.
* Venomancer's multiple slows greatly reduces Spectre's movement speed and mobility.
* Plague Wards can scout out Spectre while she is hiding in trees.
Additional:
* Venomancer's poison damage-over-time are very effective against Spectre, which is lack of magic resistance from early to mid game.
* Venomancer's multiple slows greatly reduces Spectre's low mobility, even through 
Spectral Dagger.
* Plague Wards reveals Spectre while she is hiding on trees.
Mirana
* Sacred Arrow can be used to interrupt Freezing Field from a safe distance, forcing her to cancel it to dodge or get hit.
* Crystal Maiden has very slow movement speed, making her an easy Sacred Arrow target.
* Crystal Maiden has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
* If 
Frostbite has already been used, Mirana can Leap away even when slowed by 
Crystal Nova or Freezing Field.
Mirana
* Leap allows Mirana to easily escape the freezing range of Cold Feet. Mirana also tends to build Manta Style which dispels Cold Feet.
* During Moonlight Shadow, the invisibility makes it hard to catch Mirana's team with Ice Blast.
* Ancient Apparition's lack of mobility/escape capabilities makes him an easy target for Mirana at any stage of the game.
Mirana
* Leap allows Mirana to easily escape Torrent and Ghostship.
Venomancer
* Venomancer's slows and magical damage-over-time works well against Earthshaker's which completes lack of mobility.
* Plague Wards are useful for slowing and kitting down Earthshaker, revealing him from initiating and re-initiating and putting his Blink Dagger on cooldown if Venomancer has vision over Earthshaker.
Additional:
* Earthshaker can be kited by Venomancer's slows, which is lack of mobility.
* Plague Wards is very useful for slowing and kitting down Earthshaker, revealing him from initiating and re-initiating and putting his Blink Dagger on cooldown.
Mirana
* Mirana can disturb Shadow Shaman's channeling even if he is under the effect of invisibility thanks to Sacred Arrow.
* Mirana armed with an Aghanim's Scepter is known to be able to quickly burst down heroes - especially supports. Together with Ethereal Blade the bullying towards Shadow Shaman can continue for the whole match.
Venomancer
* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* Plague Ward is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
Additional:
* Venomancer's slows and magical damage-over-time work well against Axe's complete lack of mobility.
* Plague Wards is especially useful for slowing down Axe, and revealing him before he initiates, as well as putting his Blink Dagger on cooldown.
* For the same reasons, Venomancer is a good ally for Axe when the situation is reversed.
Venomancer
* Venomous Gale, Poison Sting and Poison Nova deal damage over time and will chip away at Gravekeeper's Cloak in addition to slowing an already sluggish hero.
* Venomancer's normal attacks deal Poison Sting and will chip away at Gravekeeper's Cloak.
Venomancer
* Heroes that commonly attack ethereal units will not have any problems against Muerta's Pierce The Veil: 
Tinker, Jakiro, Lina, Luna, Pugna or Ogre Magi, Enigma, Batrider, 
Techies, Broodmother, Dawnbreaker, 
Shadow Shaman, Bane, Tinker, Venomancer, Arc Warden.
Venomancer
* In general, heroes that can slow down Dragon Knight's movement speed will do well against him. This includes Venomancer and others in addition to the heroes mentioned above.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Additional:
* If Meat Hook is used before Leap, Mirana may be able to escape Pudge's grasp by leaping to safety.
* The invisibility from Moonlight Shadow gives a degree of mobility, which can make Mirana or her teammates difficult targets to hook.
* Sacred Arrow can be used to cancel Dismember from long distances.
Venomancer
* Due to her slow movement speed,heroes with crowd control and slows can shut down Dawnbreaker:Lion, Crystal Maiden ,Venomancer etc.
Venomancer
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, 
Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Venomancer
* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, 
Meepo, Jakiro, Pugna, 
Slark, Venomancer etc.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Mirana
* Mirana can destroy Tombstone, and evade zombies using Leap and Moonlight Shadow's invisibility.
Venomancer
* Heroes who thrive on teamfights can be a problem, such as Venomancer, Necrophos, 
Centaur Warrunner...
Venomancer
* Heroes who can harass Omniknight out of lane will keep him weak in the mid game: Viper, Venomancer, Clinkz.
Venomancer
* Slardar can attack through Plague Wards and gain Bash of the Deep charges, and Templar Assassin can spill Psi Blades through Plague Wards too.
Venomancer
* Venomancer's entire arsenal deals lingering damage over a long time and therefore burns through her Refraction very quickly. Not only that, his persistent slow from Poison Sting (it can be re-applied again and again with Plague Ward) allows his team to catch up to her even with the disruption from her Psionic Trap.
Additional:
* Venomous Gale and Plague Wards allow to quickly melt through 
Refraction charges.
* Both Poison Nova and Venomous Gale hit invisible units, so 
Meld cannot be used defensively.
Venomancer
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Mirana
* Mirana can use Leap to jump right next to Drow Ranger or can approach her while under cover of the invisibility granted by Moonlight Shadow, which cancels the bonus granted to Drow Ranger by 
Marksmanship.
* Her low health makes her easy to burst down with Mirana's spells, especially with Aghanim's Scepter.
* Mirana can dodge 
Gust with good reaction time, or Leap away if Drow tries to slow her without Gust.
Mirana
* Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.
Additional:
* 
Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by 
Poof and 
Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Venomancer
* Aggressively Poofing and Earthbinding is not going to end well against Venomancer, as he will be an easy target for Noxious Plague.
* Venomancer's constant slows greatly reduce Meepo's mobility.
Mirana
* Puck can initiate on Mirana with Waning Rift to prevent her from going invisible or Leaping.
* A Mirana caught in Dream Coil will stun herself if she tries to Leap away.
* Puck's Burst damage takes advantage of Mirana's below average health.
* Puck can easily dodge Sacred Arrow and Starstorm with 
Phase Shift.
Additional:
* Mirana's spells are laid out to assassinate enemies. Puck can easily avoid the slow moving Sacred Arrow, and also can avoid Starstorm with Phase Shift, since the meteors have a delay.
* If Puck casts either Waning Rift or Dream Coil in the area, Mirana cannot Leap away.
Venomancer
* Unless Puck is facing the direction he wants to blink while in Phase Shift, the Venomous Gale and Noxious Plague combo consistently ticks many times over several seconds, making it very difficult to use Blink Dagger towards the other direction. Puck's slow turning rate makes this even worse.
* Venomancer can use Plague Wards to reveal Puck's position before he even gets a chance to initiate.
Mirana
* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.
Mirana
* Lion lacks mobility or escape mechanisms, making him an easy target for abilities like Mirana's Sacred Arrow or 
Leshrac's 
Split Earth, or combos like 
Kunkka's 
X Marks the Spot into 
Torrent.
Mirana
* Heroes that rely on invisibility can be tracked with Charge of Darkness opening them to team attacks: Bounty Hunter, Mirana, Riki
Venomancer
* Heroes that can slow Charge of Darkness by a huge amount: Venomancer, Viper, 
Dazzle, Arc Warden, Lion, Huskar, Shadow Shaman, 
Visage, 
Undying, Jakiro.
Venomancer
* Voodoo Restoration heals to counter damage over time of Poison Nova and Poison Sting.
Mirana
* Sacred Arrow can be used to interrupt Death Ward from a safe distance, forcing him to cancel it to dodge or get hit.
* 
Paralyzing Cask is a slow-moving stun, and Mirana can Leap away from her allies to keep it from bouncing.
* Witch Doctor has low health and can easily be killed with an Aghanim's Scepter combo or just when hit with an arrow.
Mirana
* 
Windrun quickly dodge Mirana's Sacred Arrow and misses her attacks.
* 
Shackleshot through tree with 
Focus Fire via Aghanim's Scepter combo can kill Mirana quickly, before using Leap or Moonlight Shadow.
Venomancer
* Due to lack of magic resistance, Venomancer poisons eats through Windranger's health.
Additional:
* Due to lack of magic resistance, Venomancer abilities eats through Windranger's health.
* Venomancer's multiple slows, to an extent, negates Windrun's mobility.
Mirana
* Low-health, normally mobile carries who rely entirely on raw attack damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, 
Juggernaut, Meepo, Mirana, Monkey King, 
Morphling, 
Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, 
Terrorblade, 
Troll Warlord, 
Weaver.
Mirana
* Heroes that cannot move in fights such as a Dueling Legion Commander or anyone channeling a spell like Bane, Pudge, or Enigma are easy Sacred Arrow targets.
Mirana
* 
Track detects Mirana and her allies during Moonlight Shadow.
Venomancer
* Venomancer's magical damage-over-time poisons greatly reduce Bounty Hunter's mobility.
* Venomous Gale, combined with Plague Wards and Poison Nova with True Sight items can allow Venomancer and his teammates to gank Bounty Hunter while he is roaming alone.
Mirana
*
Moonlight Shadow does little good against Dragon Slave and Light Strike Array.
Moonlight Shadow.
Eul's Scepter of Divinity is an item Lina commonly buys, which in combination with and 
Light Strike Array can disable Mirana if she tries to Leap away.
Laguna Blade's magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage takes advantage of Mirana's below average health.
* Lina's damage burst can quickly kill Mirana's teammates before she saves them with
Additional:
*
*
Venomancer
* Venomancer has low health, which makes him vulnerable to Lina's heavy magic damage.
Plague Wards easily in all stages of the game.
* Fiery Soul attack speed bonus removes