* Counterspell's bonus magic resistance causes the Waveform and Adaptive Strike combo to deal significantly less damage.
* Counterspell's active component can reflect the Adaptive Strike back into Morphling, dealing significant damage or even killing him.
* Mana Break combined with Manta Style can quickly burn away Morphling's mana, leaving him unable to use his spells. Black King Bar can no longer be reliably used against Anti mage due to its 50 mana cost.

* Mana Break quickly eats away at Bristleback's small mana pool, preventing him from spamming Viscous Nasal Goo and Quill Sprays.
* Bristleback has no innate mobility. Bristleback is easily kited by Blink, ignoring the protection from Bristleback.
Additional:
* Mana Break removes both a percentage and flat amount of your mana, preventing you from using abilities in the lane.
* Blink Anti-Mage has very high mobility with this skill, and can easily escape from you since you have no way to prevent his blink. He can also use this offensively to get in front of you during fights.

* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.

* Sanity's Eclipse only triggers Bristleback's passive once, and deals high damage against Bristleback's low intelligence.
* Outworld Destroyer's high burst damage is not negated by Bristleback's passive, So even if Bristleback turns his back on Outworld, Outworld Destroyer can decimate Bristleback quickly,
* If Bristleback attempts to flee, or tries to close the gap, Outworld can banish him with Astral Imprisonment, both reducing Bristlebacks much needed mana, and allowing Outworld to move in front of him, forcing him to take the full damage from his spells, This will also allow Outworld to land a devasting Sanity's Eclipse, without it being reduced by Bristleback's passive,

* Time Dilation affects Morphling's low cooldown spells, making them unusable for a long time, rendering Morphling nearly useless.
* Morphling cannot use Attribute Shift while he is inside Chronosphere which makes it easy to kill him.

* Time Dilation prevents Bristleback from spamming his low-cooldown abilities, greatly reducing his damage and effectiveness.
* Chronosphere allows allies to reposition and hit Bristleback from the front, bypassing his defensive bonus from behind.
* Bristleback has no way to prevent Void from using Time Walk.
Additional:
* Time Dilation while Quill Spray and Viscous Nasal Goo are on cooldown will make these abilities unusable for a long time, rendering Bristleback nearly useless.
* Bristleback cannot turn inside the Chronosphere, which makes it easy to attack him from the front, completely bypassing his passive damage reduction.

* Sharpshooter can kill easy when Morphling is going on full agility strategy (Only in early and mid game).
* Scurry can help to catch up Morphling when using Waveform or for escape.

* Sharpshooter deals massive damage to Bristleback and applies a high duration disable on his passive.
* Bushwhack and Scurry can be used to easily kite Bristleback.
Additional:
* Bristleback and Warpath can be disabled by Hoodwink's Sharpshooter ability for a long period of time, reducing his both offense and defense.
* Scurry and Bushwhack can be used to kite bristleback.

* Mana Drain rapidly saps Morphling's already low mana pool, making him unable to use Waveform or Adaptive Strike. Additionally, Hex prevents these abilities as well.
* An Earth Spike and Finger of Death combo can burst an unwary Morphling down if he has his strength fully shifted to agility.

* Mana Drain is a headache for Bristleback to deal with during the laning stage, as it denies him the ability to get last hits with Quill Spray.
* Finger of Death deals high damage to Bristleback, and only triggers his passive once.

* Heroes with silencing abilities that are not blocked by Linken's Sphere, like Puck's Waning Rift, Death Prophet's Silence or Silencer's Global Silence.

* Arcane Curse stacks every time Bristleback uses an ability, forcing him to stop spamming his abilities, or take heavy health degeneration.
* Glaives of Wisdom steals intelligence both permanently and temporarily, causing mana issues for Bristleback.
* Last Word and Global Silence stops Bristleback from using his abilities altogether.
Additional:
* Bristleback will not be able to cast Viscous Nasal Goo or Quill Spray while silenced, effectively blocking a major part of the hero's damage and preventing Warpath charges from stacking.
* Arcane Curse slows Bristleback down and lasts longer the more abilities he uses. On the other hand, if he doesn't use any abilities, he will begin to lose Warpath charges.

* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, Magnus, Mirana, Monkey King, Morphling, Pangolier, Phantom Assassin, Phoenix, Puck, Queen of Pain, Riki, Sand King, Spirit Breaker, Timbersaw, Tusk.

* Essence Shift allows Slark to hit bristleback freely whether on the front or back, stealing attributes and make bristleback much less tanky.
* Pounce can be used to disengage and recover loss HP with his ultimate passive, and can return to fight in a short period while bristleback is already injured and got some of his attributes stolen.
* Dark Pact makes it near impossible to keep Viscous Nasal Goo debuff on slark.
* Although Dark Pact cannot dispel Quill Spray, means Slark will still receive quill stack damage even if he uses Shadow Dance before.
* Slark builds Silver Edge in almost every game, an item that greatly counter birstleback.

* Light Strike Array catches Morphling while he jumps in from Waveform and also prevents Morphling from using his abilities.
* Laguna Blade can kill Morphling quickly before he shifts into Attribute Shift (Strength Gain).

* Heroes who deal single instance burst damage will only proc Bristleback once: Lina, Lion.

* Ice Blast stops Morphling from gaining additional health with Attribute Shift.
* Using Attribute Shift would even bring Morphling closer to the shatter threshold.
* In the lane, Ice Vortex slows Morphling's already poor movement speed to a crawl; this, coupled with the amplification of magic damage, can set up an early kill on Morphling if Ancient Apparition has a suitable lane partner.
Additional:
* Ice Blast stops Attribute Shift (Strength Gain) from recovering adional health, and using it will even bring Morphling closer to the shatter threshold.
* In lane, Ice Vortex slows Morphling's already poor movement speed to a crawl; this, coupled with the amplification of magic damage, can set up an early kill on Morphling if Ancient Apparition has a suitable lane partner.

* Heroes that withstand damage like Timbersaw, Bristleback, Dragon Knight and others will have their durability largely reduced when hit by an Ice Blast due to the risk of shattering.

* Sacred Arrow's long stun duration can prevent Morphling from casting his Waveform or Morph Replicate, making him unable to escape and easier to gank.
* Moonlight Shadow also allows Mirana's team to surprise Morphling while he tries to push towers.
* Mirana usually buys Linken's Sphere to protect herself from single-target abilities, making Morphling's Adaptive Strike and Ethereal Blade harder to use on her.
* However, Mirana also provides a chance to become a good Morph target, allowing Morph to use Leap to run away, if necessary.

* Undying's Decay is a dangerous ability against Bristleback, as it makes him more vulnerable and reduces his tankiness.
* Undying's Tombstone together with Flesh Golem can slow Bristleback down significantly.

* Duel makes Bristleback fight Legion Commander face to face, forcing him to take full damage.
* Press the Attack dispels the slow from stacks of Viscous Nasal Goo.
Additional:
* When dueled, Bristleback will have to face Legion head on, not allowing his passive Bristleback to come into effect.

* Guardian Sprint allows Slardar to outrun Bristleback, even when slowed by Viscous Nasal Goo.
* Corrosive Haze's armor reduction makes Bristleback much less tanky.

* Morphling's high armor is primarily from morphing agility, which is reduced by Natural Order therefore making the hero very vulnerable when it has morphed a lot into agility.
* Morphling usually will Morph into high agility and low strength. This can be taken advantage of with a good stun or silence or by bursting him down before he has the time to Morph back to strength.
* Morphling is very vulnerable to Blade Mail under Natural Order and can easily burst himself down with his own auto-attacks or his magical damage combo.
Additional:
* Most of Morphling's armor comes from his high agility and it is reduced by Natural Order.
* However, the aura has only 350 range and Elder Titan can be bursted down by Morphling's nuke combo if he isn't careful.

* Shukuchi gets Weaver in front of Bristleback, negating the protection from the Bristleback passive.
* Weaver's mana break talent depletes Bristleback's mana pool, preventing him from spamming abilities.

* Necrophos's Reaper's Scythe can finish off a low-health Morphling.

* Reaper's Scythe and Heartstopper Aura deal percentage-based damage, ignoring Bristleback's high health.
* Heartstopper Aura's HP removal does not trigger Bristleback's passive.
Additional:
* Heartstopper Aura deals percentage-based damage flagged as HP removal, so it is not reduced by Bristleback, nor does it trigger passive Quill Sprays.
* Reaper's Scythe is very effective against Bristleback not only due to its percentage-based damage, but rather because it first stuns and then deals its damage, allowing Necrophos to position in front of Bristleback in time.

* Arcane Bolt's low cooldown allows him to deal consistent damage to Morphling, and is a viable way to disable Linken's Sphere.
* Ancient Seal prevents Morphling from using any of his skills, giving Skywrath Mage and his team ample time to burst Morphling down.
* Mystic Flare coupled with a stun/root can easily burst Morphling down, especially if he has more stats shifted to Agility.
* Alternatively, Morphling can use Morph to use Skywrath Mage's own silence and nukes against him.

* Morphling relies on Attribute Shift (Agility Gain) to take last-hits. Primal Beast's burst damage ability can constantly threaten Morphling, especially due to his short attack range. If forced to escape with Waveform, Primal Beast can catch up with Onslaught.

* Jumping on Axe with Waveform will make Morphling an easy target for a counter-initiation with Berserker's Call.
* Morphling is often played at low health to maximise the bonuses from Attribute Shift (Agility Gain), and also because his abilities cost health to use. This makes him especially vulnerable to Culling Blade.
* However, Morphling is common Linken's Sphere carrier to block Culling Blade forces Axe to use Battle Hunger to pop the Spell Block first.
* Attribute Shift (Agility Gain) gives Morphlig no protection against the pure damage of Culling Blade. Its attack speed bonus also means that Counter Helix will proc more often.

* Axe forces Bristleback to turn around with Berserker's Call, allowing allies to attack him without fear of his passive.

* Geomagnetic Grip is not blocked by Linken's Sphere and can silence Morphling, preventing Morphling from using Waveform or Attribute Shift to escape from ganks.
* In addition, Boulder Smash and Rolling Boulder provide a solid lockdown if used together.

* Morphling usually has low max health due to shifting strength into agility, which combined with Blast Off's silence will prevent him from using Waveform and Adaptive Strike (Strength), leaving him defenseless and making him an easy target to burst down.

* Void Spirit can greatly pressure Morphling's farm, which is very bad for a hero who needs a large amount of space.
* Waveform does not provide better mobility than Astral Step.
* If Morphling shifted all of his strength to agility, he can be bursted down by Void Spirit before he can react.
* Doing an Ethereal Blade combo on Void Spirit is incredibly difficult, as Dissimilate and Astral Step can allow him to escape or dodge the projectile.

* Whirling Death deals damage as well while reducing 15% of Bristleback's strength, which reduces Bristleback's tankiness.
* Reactive Armor can sustain through multiple Viscous Nasal Goo and Quill Spray stacks.
* Timber Chain makes it hard for Bristleback to slow down Timbersaw with Viscous Nasal Goo and build Lotus Orb can prefer reflects to Viscous Nasal Goo .

* Underlord's Atrophy Aura reduces Morphling's high base damage gained through agility shift.

* Jakiro's early pushing ability from Liquid Fire makes Jakiro very strong against heroes, that take a long time to get online: Morphling, Naga Siren, Spectre.

* While Jakiro's damage is going to be little more then average against him due to his Bristleback. His large quantity of stuns can prevent Bristleback from getting his much needed Warpath stacks, while also giving his allies a chance to counter his high defense.
* Dual Breath and Liquid Frost both reduce Movement Speed, removing one of Bristlebacks greatest strengths
* Liquid Fire reduces Bristlebacks Attack Speed, making it harder for him to burst down a hero with Warpath
* However Bristleback can generally catch and kill a lone Jakiro. Your only effective in a group

* Heroes with high health especially Strength heroes will take more damage on Sun Ray: Axe, Pudge, Bristleback, Mars.

* Heroes that rely on right-clicks will find that their attacks will miss a lot, due to Whirling Axes (Melee)'s miss chance. Such heroes include Phantom Assassin, Terrorblade, and Morphling.

* Winter Wyvern's Winter's Curse turns Morphling's high attack damage and attack speed against his targeted teammate.

* Low-health, normally mobile carries with a lot of damage are vulnerable to Bane's nukes and disables: Anti-Mage, Clinkz, Drow Ranger, Faceless Void, Gyrocopter, Juggernaut, Luna, Meepo, Mirana, Monkey King, Morphling, Phantom Assassin, Phantom Lancer, Riki, Shadow Fiend, Slark, Sniper, Terrorblade, Troll Warlord, Weaver.

* Batrider's turn rate slow from Sticky Napalm makes it harder for Bristleback to keep his back towards the enemy.

* Shadow Demon's Demonic Purge with Aghanim's Scepter disables Bristleback's passives.

* Heroes with high base damage (Morphling, Tiny, Drow Ranger), heroes with mana burning abilities (Anti-Mage), and Diffusal Blade users (Juggernaut or Riki) will suffer from Reflection's illusions.

* Terrorblade's Sunder is not affected by the Bristleback damage reduction.

* While Morphling can burst her down with Adaptive Strike (Agility), Death Prophet does have tools to disrupt him. A Morphling affected by Silence makes it unable to use Attribute Shift (Strength Gain) to increase its health pool or use Waveform to escape.

* Infernal Blade deals scaling damage and is useful against high health targets such as Bristleback.
* Doom disables Bristleback's low cooldown abilities, preventing him from triggering Warpath. With his upgraded level 25 talent, it also breaks Bristleback's passive, rendering him more vulnerable.
Additional:
* Infernal Blade deals scaling damage and is useful against high HP targets such as Bristleback.
* Doom prevents Bristleback from casting his two low cooldown abilities, which then prevents him from utilizing Warpath.
* If Doom gets an Aghanim's Scepter, he can disable Bristleback and Warpath, taking away much of his durability and damage potential in team fights.

* Phantom's Embrace silences Viscous Nasal Goo and Quill Spray.
* Ink Swell stuns Bristleback and gets allies in position faster with increased movement speed to attack his front, countering his passive ability.