* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of Song of the Siren.
* Naga Siren is not a hero that likes to go for Black King Bar, and that makes her very vulnerable to Jakiro's damage over time in every phase of the game.
Additional:
* Jakiro's damage over time abilities can clear Naga Siren's illusions and can hurt real Naga Siren even for the duration of Song of the Siren.
* Naga Siren is not a hero that likes to go for Black King Bar, and that makes her very vulnerable to Jakiro's damage over time in every phase of the game.

* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.

* All of Leshrac's abilities, especially Pulse Nova, can easily deal with Naga Siren's illusions.

* Io is a hero who needs to be close to it's tethered target to make it effective, and that's where Leshrac gets the advantage thanks to many of his area-of-effect abilities.
* Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to both, Io and its tethered target.
Additional:
* Lightning Storm will usually hit both Io and his Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.

* Many stacks of Sticky Napalm, combined with Flamebreak and Firefly, allows Batrider to destroy illusions from Mirror Image.
* If Batrider can manage to destroy all illusions from Naga Siren, he will be able to use Flaming Lasso on the real one, and will be able to drag her toward his team, potentially preventing Naga Siren from escaping with Song of the Siren.
Additional:
* Many stacks of Sticky Napalm, combined with Flamebreak and Firefly, allows Batrider to destroy illusions from Mirror Image.
* If Batrider can manage to destroy all illusions from Naga Siren, he will be able to use Flaming Lasso on the real one, and will be able to drag her toward his team, potentially preventing Naga Siren from escaping with Song of the Siren.

* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Additional:
* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.

* Axe will destroy her illusions by proccing Counter Helix more often due to him being hit by more attacks.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Heroes with long-lasting, undispellable debuffs will pinpoint the true Naga Siren: Spirit Breaker, Bloodseeker.

* Thirst allows Bloodseeker to see where Io relocated to, should either Io or the tethered hero have low health.
* Rupture forces Io to stay in place, preventing it from using the Tether bonus movement speed to escape.

* Heroes with long-lasting, undispellable debuffs will pinpoint the true Naga Siren: Spirit Breaker, Bloodseeker.

* Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* Greater Bash and Nether Strike is devastating due to Io's low armor, and can even knock it away from tethered target.

* Heroes who are reliant on illusions or summons: Chaos Knight, Broodmother, Naga Siren.

* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.
Additional:
* Grimstroke can catch Io and his ally easily with Soulbind as Io has a tendency to tether himself with an ally frequently.
* Io is highly vulnerable to disables. Hence, Grimstroke's Phantom's Embrace is a great ability to hinder Io's potential.

* Since Naga Siren is not a hero that likes to go for Black King Bar, she is vulnerable to nukers with strong magical damage and big area-of-effect spells in every game more than any other carry heroes: Sand King, Jakiro, Leshrac, Lina, Earthshaker, Zeus.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Heroes that heavily depend on illusions or summons, (Naga Siren, Terrorblade, Phantom Lancer, Lycan,...) are vulnerable to Sleight of Fist and even more so if Ember Spirit has Battle Fury.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Living Armor can be used to save a hero from a Relocate gank.

* Burning Barrage and Searing Arrows allow Clinkz to quickly kill Io due to its low armor.
* Clinkz iz a hero that very often goes for Orchid Malevolence, and its upgrade Bloodthorn. And if Clinkz has it, he will be able to silence Io and prevent him from escaping wit either Tether or Relocate.

* Mirror Image's illusions increase Echo Slam's damage.
Additional:
* Earthshaker's strong AoE abilities can clear Naga Siren's illusions, or at least make it easier to distinguish the real one by the damage they take.
* Echo Slam deals more damage against more enemies, which can be devestating against Naga Siren and her illusions.

* Sanity's Eclipse will likely instantly kill all illusions.

* Lich's Chain Frost forces Io to either give up providing buff to his ally with Tether or suffer devastating damage with his tethered ally.
* Lich can easily use Sinister Gaze to disable Io from getting away with Tether or Relocate.

* Flak Cannon and Call Down can easily clear Naga Siren's illusions.

* Ice Blast prevents Io from healing an ally with Tether and prevents healing from Overcharge
* Io is a common Mekansm builder which is useless if he is affected by Ice Blast.
Additional:
* Ice Blast prevents Io from healing the target.

* Luna can easily cancel channeling spells with Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse, she can also buy Abyssal Blade in case they decide to buy Black King Bar: Enigma's Black Hole, Witch Doctor's Death Ward, Shadow Shaman's Shackles, Lion's Mana Drain, Bane's Fiend's Grip, Pudge's Dismember, Crystal Maiden's Freezing Field, Pugna's Life Drain, Dawnbreaker's Solar Guardian, and Naga Siren's Reel In from Aghanim's Scepter.

* Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's Diabolic Edict, Lightning Storm and Pulse Nova abilities. Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Additional:
* Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse can be used to cancel both, Tether and Relocate.
* Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.

* Zeus' abilities deal high amounts of burst magical damage, which ignores Naga Siren's high armor.
* Zeus' Arc Lightning is also a good way to destroy Naga Siren's illusions.

* Mortimer Kisses can make quick work of Naga Siren's illusions.
* Scatterblast and Firesnap Cookie's AoE damage are also decent ways to deal with Naga's illusions.

* Cold Embrace can render the extra attack speed from Overcharge meaningless.
* Splinter Blast and Winter's Curse are very affective against Io, as it has to stay close to its tethered hero.

* Fireblast is a good tool to interrupt Io during its escapes through Tether.
* Ignite can be one of the few spells with enough total damage to out-trade the sustained healing Io provides for its fellow laner.
* However, picking other supports that focus less on the laning phase is generally a better choice against Io.

* Avalanche and Toss combo makes short work of Mirror Image's illusions.
* Tiny's cleave with Tree Grab and area of effect damage with Tree Volley will easily wipe out illusions.

* Cleave heroes will clear her illusions. Such heroes include Sven, Magnus, Dragon Knight in Elder Dragon Form, Ember Spirit (via item), Phantom Assassin (via talent or item), etc.

* Phantom Strike allows Phantom Assassin jump directly to Io.
* Coup de Grace can make a short work of Io's low health and armor.

* Timbersaw's innate durability is very hard to deal with as Naga Siren as she relies on sustained damage rather than burst damage. Timbersaw's high Pure Damage and low-cooldown AoE nukes can also destroy Naga Siren's illusions very fast. Timbersaw can also build Lotus Orb reflects Ensnare

* Both Hex and Mana Drain destroy Naga Siren's illusions in an instant, making it hard to teamfight or push against a team with Lion. If Lion chooses the AoE effect talent for Hex or the shard for multi-target Mana Drain, it can negate her pushing potential entirely.
* Earth Spike is an AoE disable with good damage. If used well, it can help distinguish the true Naga Siren by the damage they take (illusions take more damage).

* Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirit's weak area-of-effect: Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock.

* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirit's weak area-of-effect: Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Heroes that rely on illusions will suffer against Ion Shell, which kills them very quickly: Phantom Lancer, Chaos Knight, Naga Siren, Meepo.

* Heroes who are reliant on illusions: Chaos Knight, Phantom Lancer, Naga Siren.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirit's weak area-of-effect: Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock.

* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirit's weak area-of-effect: Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Since Naga Siren is not a hero that likes to go for Black King Bar, she is vulnerable to nukers with strong magical damage and big area-of-effect spells in every game more than any other carry heroes: Sand King, Jakiro, Leshrac, Lina, Earthshaker, Zeus.

* Illusion heroes will struggle against Primal Beast's area damage capability, such as Chaos Knight, Naga Siren, Terrorblade.

* Heroes with long cast animations can be continuously interrupted by Battery Assault: Centaur Warrunner, Jakiro, Leshrac, Naga Siren, Underlord.

* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.

* Squishy heroes (Io, Crystal Maiden, Lina...), as Earth Spirit can deal tons of damage with Magnetize.

* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirit's weak area-of-effect: Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock.

* Keeper of the Light can stall pushes with Illuminate. This makes him strong against pushing heroes: Terrorblade Naga siren Nature's Prophet and Anti-Mage

* As long as Windranger is able to identify the real hero among the illusions, heroes relying on them can be easily tagged with Focus Fire: Chaos Knight, Terrorblade, Phantom Lancer, Naga Siren.

* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Cleave heroes will clear her illusions. Such heroes include Sven, Magnus, Dragon Knight in Elder Dragon Form, Ember Spirit (via item), Phantom Assassin (via talent or item), etc.

* Cleave heroes will clear her illusions. Such heroes include Sven, Magnus, Dragon Knight in Elder Dragon Form, Ember Spirit (via item), Phantom Assassin (via talent or item), etc.

* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.
Additional:
* Glimpse directly negates Relocate.
* Kinetic Field prevents Io from escaping with Tether.
* Static Storm can silence and damage both, Io and it's tethered target. And it can also mute both, Io and it's tethered target when upgraded with Aghanim's Scepter

* Medusa's Split Shot will whittle down all of Naga Siren's illusions, including Naga Siren herself.