Night Stalker
* Void's slow is useless against Lycan by activating 
Shapeshift.
* Night Stalker's single target abilities (with the exception of Void upgraded by 
Aghanim's Scepter) is not very effective against Lycan's 
Summon Wolves during the early and mid game.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: 
Beastmaster, 
Broodmother, 
Chaos Knight, 
Lycan, 
Naga Siren, 
Nature's Prophet, 
Phantom Lancer, 
Shadow Shaman, 
Terrorblade, 
Visage, 
Warlock, 
Wraith King.
Night Stalker
* Heroes that can punish aggressive heroes, such as: 
Leshrac, 
Shadow Demon, 
Pugna, 
Death Prophet.
Io
* Io is a hero who needs to be close to it's tethered target to make it effective, and that's where Leshrac gets the advantage thanks to many of his area-of-effect abilities.
* 
Lightning Storm will usually hit both Io and its tethered target since both will be close enough for the lightning to jump.
* 
Diabolic Edict and 
Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to both, Io and its tethered target.
Additional:
* Lightning Storm will usually hit both Io and his 
Tethered target since both will be close enough for the lightning to jump. It can then be followed up by Split Earth.
* Diabolic Edict and Pulse Nova hit all units near Leshrac, meaning he can do colossal damage to Io and his Tethered target.
Night Stalker
* 
Bloodseeker's 
Rupture turns Night Stalker mobility against him and 
Thirst grants movement speed bonus and vision prevents Night Stalker from initiating and re-initiating.
Io
* Thirst allows Bloodseeker to see where Io relocated to, should either Io or the tethered hero have low health.
* Rupture forces Io to stay in place, preventing it from using the Tether bonus movement speed to escape.
Night Stalker
* Heroes with illusions and summons can manfight Night Stalker: Terrorblade, Beastmaster, Broodmother.
Io
* Terrorblade can easily take advantage of Io's weak durability with 
Reflection and 
Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with 
Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* 
Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from 
Conjure Image and 
Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with 
Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and his Tethered target to escape with 
Relocate besides 
Terror Wave from Aghanim's Scepter.
Additional:
* Terrorblade can easily take advantage of Io's weak durability with Reflection and Metamorphosis.
* As Io relies on boosting his and his Tethered target's attack speed with Overcharge, Terrorblade can take advantage of this with Reflection, which can damage and slow both, Io and his Tethered target.
* Spirits's weak area-of-effect makes it a bad tool to deal with Terrorblade's illusions from Conjure Image and Manta Style.
* Io's damage output is one of the weakest, therefore Terrorblade will have plenty of time to save himself with Sunder.
* However, Terrorblade has no way of stopping Io to escape with Tether or to stop both, Io and it's Tethered target to escape with Relocate besides Terror Wave from Aghanim's Scepter.
Night Stalker
* Void's slow is dispelled by 
Doppelganger or counteracted by 
Phantom Rush.
* 
Spirit Lance's and 
Diffusal Blade's slow reduces Night Stalker's mobility and helps him or his ally escape if they're inflicted by Void or Crippling Fear.
* Night Stalker has no AoE abilites to take out Phantom Lancer's illusions. Even if Night Stalker gets an Aghanim's Scepter, there will be way too many illusions for Night Stalker to handle.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Night Stalker
* Heroes with stronger lane presence that can threaten to kill him: 
Batrider, 
Juggernaut, 
Ursa, 
Monkey King, 
Razor.
Io
* Batrider's 
Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying 
Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Additional:
* Batrider's Flaming Lasso can be used to cancel Io's attempts to escape with Relocate and drag him away from his Tethered target. And since Io doesn't like buying Linken's Sphere, he will be always vulnerable to Batrider's initiations.
* Io's tendency to stick close to it's Tethered target can make Io and it's target vulnerable to Batrider's harrasing.
* Aghanim's Scepter upgraded Flaming Lasso allows Batrider to catch and drag two heroes at once, not just one. Which can potentially turn Io's Tether against him.
Night Stalker
* Heroes with illusions and summons can manfight Night Stalker: Terrorblade, Beastmaster, Broodmother.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Night Stalker
* 
Night Stalker is all about right-clicks. His nuke, 
Void is also not that threatning once you have 
Hood of Defiance, your core item.
Io
* Heroes that are hard to gank: 
Axe, Death Prophet, Phantom Lancer, 
Slark, 
Centaur Warrunner, 
Bristleback, 
Medusa, 
Mars.
Night Stalker
* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, Pugna, Death Prophet.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Night Stalker
* Phantasm gives Chaos Knight a significant advantage against single-target damage dealers: 
Lifestealer, Wraith King, Night Stalker, 
Troll Warlord.
Additional:
* 
Chaos Bolt can stun Night Stalker outside of Crippling Fears relatively small radius.
* 
Reality Rift is a great way to force Night Stalker to fight Chaos Knight, a hero with massive health and damage output. It also forces Night Stalker's Crippling Fear off his primary target.
* Night Stalker doesn't have a lot of ways to deal with multiple targets, which makes him vulnerable to 
Phantasm illusions unless Night Stalker buys Aghanim's Scepter.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Night Stalker
* Heroes that are hard to gank: 
Dragon Knight, Mars, Centaur Warrunner.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Night Stalker
* Heroes with illusions and summons can manfight Night Stalker: Terrorblade, Beastmaster, Broodmother.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* 
Cold Embrace can render the extra attack speed from Overcharge meaningless.
* 
Splinter Blast and 
Winter's Curse are very affective against Io, as it has to stay close to his Tethered target.
Io
* 
Poison Touch allows Dazzle to harass both, Io and it's tethered target on lane. 
Aghanim's Shard upgraded Poison Touch can also hex both, Io and it's tethered target, preventing them from escaping with Relocate, and also disarming them, silencing them, muting them and rendering them helpless against Dazzle and his allies.
* Io's damage output is one of the weakest, therefore Dazzle will have plenty of time to save an ally with 
Shallow Grave from gank by Io and it's tethered target.
* 
Shadow Wave will always hit both, Io and it's tethered target if they are near the ally Dazzle uses Shadow Wave on, while healing Dazzle's allies near them. Aghanim's Scepter upgraded Shadow Wave can bounce on both, Io and it's tethered target, causing them both to take damage and to be attacked by Dazzle. And unlike Io who doesn't get healed while using Tether, Shadow Wave will always heal Dazzle no matter on which of his allies he uses it on.
* 
Bad Juju will cause both, Io and it's tethered target to lose armor every time Dazzle casts a spell while strengthening armor of Dazzle's allies.
Additional:
* Poison Touch allows Dazzle to harass both, Io and it's Tethered target on lane. Aghanim's Shard upgraded Poison Touch can also hex both, Io and it's Tethered target, preventing them from escaping with Relocate, and also disarming them, silencing them, muting them and rendering them helpless against Dazzle and his allies.
* Io's damage output is one of the weakest, therefore Dazzle will have plenty of time to save an ally with Shallow Grave from gank by Io and it's Tethered target.
* Shadow Wave will always hit both, Io and it's Tethered target if they are near the ally Dazzle uses Shadow Wave on, while healing Dazzle's allies near them. Aghanim's Scepter upgraded Shadow Wave allows Dazzle Shadow Wave directly on Io and it's Tethered target which can also bounce on both, Io and it's tethered target, causing them both to take damage and to be attacked by Dazzle. And unlike Io who doesn't get healed while using Tether, Shadow Wave will always heal Dazzle no matter on which of his allies he uses it on.
* Bad Juju will cause both, Io and it's tethered target to lose armor every time Dazzle casts a spell while strengthening armor of Dazzle's allies.
Io
* 
Quill Spray is very effective against Io, as it has very low armor and has to stay close to the fight to not break its Tether.
Io
* Fireblast is a good tool to interrupt Io during its escapes through Tether.
* Ignite can be one of the few spells with enough total damage to out-trade the sustained healing Io provides for its fellow laner.
* However, picking other supports that focus less on the laning phase is generally a better choice against Io.
Io
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* 
Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys 
Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and 
Macropyre.
Additional:
* Jakiro's area-of-effect ability arsenal allows him to affect multiple heroes at once, giving Io difficulties in saving them as he can only heal one hero at a time with Tether.
* Ice Path can be used to cancel both, Tether and Relocate.
* Jakiro commonly buys Rod of Atos that can be used to cancel Relocate, prevent Io in escaping with Tether and make Io easy target for Ice Path and Macropyre.
Io
* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.
Additional:
* Grimstroke can catch Io and his Tethered ally easily with 
Soulbind as Io has a tendency to Tether himself with an ally frequently, which also makes them easier targets for Soulbind.
* Io is highly vulnerable to disables. Hence, Grimstroke's 
Phantom's Embrace is a great ability to hinder Io's potential.
Io
* 
Living Armor and 
Leech Seed can be used to save a hero from a Relocate gank.
* 
Overgrowth can be used to cancel escape attempts with Relocate.
* Once Treant Protector buys Aghanim's Scepter, he will gain access to 
Eyes in the Forest, that will allow him to enchant a tree which will grant him unobstructed vision in that location, allowing him to keep his allies alerted on Io and his Tethered's attempts to gank them, and which can also allow Overgrowth to damage them and root them if they are within a 800 radius of an tree affected by Eyes in the Forest.
Night Stalker
* 
Whirling Axes (Melee) provides a 60% miss chance, which can make the attack speed bonus from Hunter in the Night largely ineffective.
* 
Berserker's Rage together with 
Battle Trance and 
Fervor stacks gives him a high chance of rooting Night Stalker, which allows Troll Warlord to man-fight Night Stalker in any stage of the game, regardless of whether or not it's night.
* Night Stalker is not a common 
Monkey King Bar carrier to counteract this problem.
Night Stalker
* 
Warcry makes it difficult to burst Sven down with both the passive (with Aghanim's Shard) and active component.
* Sven under the effect of 
God's Strength and his massive physical damage make Sven very dangerous to engage in the mid game.
Io
* 
Lucent Beam can be used to cancel both, Tether and Relocate.
* Like with Leshrac's Diabolic Edict, Lightning Storm and Pulse Nova abilities. Luna's 
Moon Glaives and 
Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Additional:
* Lucent Beam and 0.25s Eclipse Lucent Ministun talent for Eclipse can be used to cancel both, Tether and Relocate.
* Luna's Moon Glaives and Eclipse abilities can make short work of Io and its tethered ally, particularly when upgraded with Aghanim's Scepter.
Io
* 
Phantom Strike allows Phantom Assassin jump directly to Io.
* 
Coup de Grace can make a short work of Io's low health and armor.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes that can easily bypass Io's allies to get to Io: 
Riki, 
Tusk, 
Clinkz, 
Sniper, Slark, 
Phantom Assassin, 
Void Spirit, 
Storm Spirit, 
Ember Spirit, 
Earth Spirit, 
Spirit Breaker, Lifestealer.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Heroes whose abilities can affect multiple enemies at once: 
Dawnbreaker, Ember Spirit, 
Lina, 
Luna, 
Jakiro, Leshrac, 
Invoker, 
Muerta, 
Dazzle.
Io
* Heroes with either magical, physical or pure damage burst: 
Bane, Ember Spirit, Leshrac, Lina, Luna, 
Nyx Assassin, Phantom Assassin, 
Skywrath Mage, 
Tinker, Ursa, Void Spirit.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Io
* Squishy heroes (
Io, 
Crystal Maiden, Lina...), as Earth Spirit can deal tons of damage with Magnetize.
Night Stalker
* Heroes with stronger lane presence that can threaten to kill him: Batrider, Juggernaut, Ursa, Monkey King, Razor.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Night Stalker
* Heroes with weaker mobility will struggle to keep up with Night Stalker: 
Gyrocopter, Ursa, 
Drow Ranger
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Night Stalker
* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, Pugna, Death Prophet.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Night Stalker
* Heroes that are hard to gank: Dragon Knight, Mars, Centaur Warrunner.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Night Stalker
* Heroes that rely on slows to get kills: Lifestealer, Night Stalker, Ursa, Phantom Assassin, Terrorblade.
Night Stalker
* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, Pugna, Death Prophet.
Night Stalker
* Heroes with stronger lane presence that can threaten to kill him: Batrider, Juggernaut, Ursa, Monkey King, Razor.
Night Stalker
* Heroes with stronger lane presence that can threaten to kill him: Batrider, Juggernaut, Ursa, Monkey King, Razor.
Io
* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker, Muerta, Dazzle.
Io
* Heroes with the ability to heal allies will not be able to heal heroes affected by 
Doom: 
Chen, Dazzle, Io, 
Oracle, 
Omniknight, 
Witch Doctor, 
Winter Wyvern, 
Abaddon, etc.
Io
* Ice Blast prevents Io from healing an ally with Tether and prevents healing from Overcharge
* Io is a common 
Mekansm builder which is useless if he is affected by Ice Blast.
Additional:
* 
Ice Blast prevents Io from healing the target.
* Ancient Apparition can easily harass Io on lane with 
Chilling Touch due to it's high range and damage. This can get even worse if Ancient Apparition buys Aghanim's Scepter and combines it with items that can give him bonus attack damage and attack speed.
* Chilling Touch combined with 
Ice Vortex makes it nearly impossible for Io to escape from 
Cold Feet. Ice Vortex can also make Io and it's tethered target more vulnerable to Ancient Apparition and his allies's magical damage.
Night Stalker
* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, 
Queen of Pain, Phantom Assassin, 
Windranger, 
Bounty Hunter, Spirit Breaker, Night Stalker, Storm Spirit, Juggernaut, etc.
Io
* 
Charge of Darkness can be used to escape or counter-initiate against a Relocate gank.
* 
Greater Bash and 
Nether Strike is devastating due to Io's low armor, and can even knock it away from his Tethered target.
Night Stalker
* Heroes that have a weak laning stage: 
Spectre, Nyx Assassin, 
Clockwerk, Spirit Breaker, Omniknight, 
Pudge.
Io
* Lich's 
Chain Frost forces Io to either give up providing buff to his ally with Tether or suffer devastating damage with his Tethered ally.
* Lich can easily use 
Sinister Gaze to disable Io from getting away with Tether or Relocate.
Night Stalker
* Heroes with low health: 
Lich, Crystal Maiden, 
Lion.
Io
* 
Homing Missile can be used to cancel escape attempts with Relocate.
* 
Flak Cannon allows Gyrocopter to attack both, Io and his Tethered target, especially when upgraded with Aghanim's Scepter.
* 
Rocket Barrage and 
Call Down allow Gyrocopter to deal serious damage to both Io and his Tethered target.
Additional:
* Homing Missile can be used to cancel escape attempts with Relocate.
* Flak Cannon allows Gyrocopter to attack both, Io and his Tethered target, especially when upgraded with Aghanim's Scepter.
* Rocket Barrage and Call Down allow Gyrocopter to deal serious damage to both Io and his Tethered target.
Night Stalker
* Heroes with weaker mobility will struggle to keep up with Night Stalker: Gyrocopter, Ursa, Drow Ranger
Io
* 
Take Aim and 
Assassinate allow Sniper to reach Io even if it stays in the backline.
Io
* Heroes with high mobility can approach Sniper: 
Anti-Mage, Earth Spirit, Io, Nature's Prophet, 
Pangolier, 
Puck, Queen of Pain and most notably Riki.
Night Stalker
* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.
Additional:
* Void's mini-stun and silence from 
Crippling Fear will stop Pudge from using Dismember or turning off his Rot.
* Night Stalker has naturally high health, strength gain and common itemization for survivability through magic resistance, making Night Stalker a poor target for Pudge.
Io
* Tether and Overcharge makes it much harder for Pudge to kill a target with 
Meat Hook, and Relocate can save the Io's ally while 
Dismember is being channeled.
Night Stalker
* Heroes with weaker mobility will struggle to keep up with Night Stalker: Gyrocopter, Ursa, Drow Ranger
Io
* Drow Ranger's lack of escape abilities makes her an easy target for Relocate ganks.
Night Stalker
* 
Phoenix turns night to day, overriding Dark Ascension during 
Supernova.
Night Stalker
* Void can interrupt 
Icarus Dive.
* His Crippling Fear's silence will shutdown a spell caster Phoenix.
* However, Phoenix punishes Night Stalker with Supernova because it will turn night into day, and it has a higher priority than 
Dark Ascension, effectively canceling the passive bonuses Night Stalker gets from 
Hunter in the Night.
Io
* Phoenix's limit AoE, damage-over-time abilities give Io plenty of time to save allies with Relocate.
Night Stalker
* Dark Ascension also allows Night Stalker to fly over Proximity Mines without triggering them.
* Crippling Fear is effective in stopping Techies from using Blast Off and Void is effective in stopping them from running to the safety of their mines.
Night Stalker
* Dark Ascension reduces vision for the enemy team, which makes it more difficult for Magnus to initiate with Blink Dagger and Reverse Polarity. It is also more likely that Night Stalker will scout out Magnus with Aghanim's Scepter and a 
Gem of True Sight, after which he can silence Magnus with Crippling Fear.
Night Stalker
* Void can be used to cancel Requiem of Souls.
* Crippling Fear prevents Shadow Fiend from using Shadowraze or Requiem of Souls.
* With Dark Ascension and Gem of True Sight, Night Stalker can find and kill Shadow Fiend easily. He is also a tanky hero that can fight Shadow Fiend at any stage of the game.
Night Stalker
* Crippling Fear silences nearby heroes and cannot be dispelled, which hinders Rubick's way to retaliate when being jumped on.
* With Hunter in the Night and Dark Ascension, Night Stalker can find Rubick easily in teamfights. The two spells grants more than enough damage to hunt Rubick down without defensive items.
Io
* Io can escape from Pit of Malice with Tether or Relocate.
* Relocate can counter Dark Rift's split pushing.
Night Stalker
* Night Stalker has a huge, almost instant silence through Crippling Fear. The main problem is that he can get it off while Queen of Pain barely has any vision of him if he creeps up to her during Dark Ascension. She'll have to play very carefully before she gets a 
Black King Bar or a 
Eul's Scepter of Divinity.
Night Stalker
* Crippling Fear can silence Faceless Void for a long time, preventing him from using his Time Walk and Chronosphere.
Night Stalker
* Crippling Fear prevents Keeper of the Light from using his spells to keep his team alive during team-fights.
* Dark Ascension is very strong against Keeper of the Light, as it allows Night Stalker to jump the backline and quickly kill the squishy Ezalor, especially when combined with the slow from Void.
Additional:
* Keeper of the Light's Aghanim's Scepter upgrade loses much of its power, due to Night Stalker being able to reduce the duration of daytime by a lot.
Night Stalker
* The long silence of Crippling Fear at night prevents Weaver from using his Shukuchi or Time Lapse.
* With Dark Ascension and Gem of True Sight, Night Stalker can easily find and probably kill Weaver.
* Hunter In the Night's attack speed bonus removes The Swarm's beetles very quickly.
Night Stalker
* Puck cannot use any of its normal means to survive should Night Stalker catch it within Crippling Fear, and goes down quickly.
Additional:
* Void is a potent nuke that is devastating to Puck's low health pool.
* Crippling Fear silence can prevent Puck from casting spells, leaving it vulnerable.
Night Stalker
* The long silence of Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With Dark Ascension and Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.
Night Stalker
* Crippling Fear makes Night Stalker one of the best early game gankers to shut down Anti-Mage.
* Night Stalker's low mana pool causes him to take little damage from Mana Void.
Night Stalker
* Heroes with low mobility that rely on spells: 
Zeus, Lina, Crystal Maiden.
Night Stalker
* Heroes with low mobility that rely on spells: Zeus, Lina, Crystal Maiden.
Night Stalker
* Heroes with low health: Lich, Crystal Maiden, Lion.
Night Stalker
* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.
Night Stalker
* Heroes that have long silences, such as Night Stalker and 
Silencer, will prevent Abaddon from saving his allies effectively and disable the active component of Borrowed Time.
Night Stalker
* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.
Night Stalker
* Earthshaker must be careful not to use 
Blink Dagger or Aghanim's Scepter upgraded 
Enchant Totem to blink into Riki's 
Smoke Screen or Night Stalker's Crippling Fear, as these field effects will instantly silence Earthshaker and prevent him from initiating.
Additional:
* 
Fissure has a short stun and creates an impassable ridge. However, Night Stalker can fly over it during Dark Ascension.
* Night Stalker can find Earthshaker, disable his Blink Dagger with Void, and then take him out with Crippling Fear.
* Earthshaker may fail his blink combo against Night Stalker's team if he is not careful, as he can blink into the silence.
Night Stalker
* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.
Night Stalker
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, 
Doom .
Night Stalker
* Heroes with long disables, like Lion, Night Stalker, or 
Legion Commander, can prevent Oracle from using spells or items.
Io
* Heroes with both illusions and summons, for Io has nothing to deal with multiple enemies at once outside from Spirits's weak area-of-effect: Beastmaster, Broodmother, Chaos Knight, Lycan, Naga Siren, Nature's Prophet, Phantom Lancer, Shadow Shaman, Terrorblade, Visage, Warlock, Wraith King.
Io
* Nature's Prophet is extremely easy to gank with Relocate while he's split pushing.
* Tether on a friendly unit can destroy Nature Prophet's trees should he surround himself with 
Sprout as a defense.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Night Stalker
* Storm Spirit is absolutely helpless if caught within Night Stalker's silence range.
* Common items a Storm Spirit will build will not remove the AoE silence.
Additional:
* Crippling Fear is a silence that can last up to 8 seconds during night, rendering Storm Spirit tied limited to his items in a fight.
* Dark Ascension allows Night Stalker to initiate on Storm Spirit across the impassable terrain around the middle lane, rendering Storm vulnerable in the early game and prevent him from snowballing.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Night Stalker
* With Dark Ascension and Gem of True Sight, Night Stalker can easily find and kill Riki. Riki will also find it harder to kill the tanky Night Stalker than he would many other heroes.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Night Stalker
* With Dark Ascension he can keep vision on Slark, disabling his 
Shadow Dance regeneration.
* Night Stalker is very fast so without the Pounce in lane, he can simply out distance him during the night.
* Slark is matched in night vision by only a few heroes, Night Stalker happens to be one of them.
Io
* Heroes that are hard to gank: Axe, Death Prophet, Phantom Lancer, Slark, Centaur Warrunner, Bristleback, Medusa, Mars.
Night Stalker
* Crippling Fear makes it so Axe might use Blink Dagger right into an AoE silence in the middle of everyone.
* Void cripples Axe's already bad movement speed and attack speed.
* Hunter in the Night makes it impossible for Axe to catch up to fleeing or escape from Night Stalker during the night.
* Lastly, Dark Ascension gives full vision over Axe before he initiates, making the opponents all recognize his location immediately and allowing Night Stalker to prevent it or vocally tell his team if needed.
* Night Stalker has very high strength gain, even in the lane, so a successful Culling Blade is very unlikely.
* Axe's 
Blade Mail will likely do nothing to Night Stalker because of his high health and certain requirements for him to do the most damage to be true.
Io
* Heroes whose abilities can affect multiple enemies at once: Dawnbreaker, Ember Spirit, Lina, Luna, Jakiro, Leshrac, Invoker, Muerta, Dazzle.
Night Stalker
* Crippling Fear is a good way to shut down and gank Invoker in the early game..
* Void deals good damage to Invoker and makes escaping harder.
* With Hunter in the Night and Void, Invoker can't get away from Night Stalker and won't be able to catch him with Sun Strike during the night.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Night Stalker
* Night Stalker is one of the best heroes to find (and silence) Tinker in the trees during Dark Ascension.
Additional:
* Night Stalker can easily find Tinker in the trees during Dark Ascension.
* Void's mini-stun will stop Rearm and 
Keen Conveyance
* Crippling Fear's silence will prevent Tinker from fighting back, as Tinker relies on his spells.
Night Stalker
* Night Stalker's most skills are single targeted which allows other Meepos to Poof, Earthbind and kill him.
Io
* Tether helps Io escape from Earthbind even if Meepo has Blink Dagger.
* Io's Spirits can pressure Meepo while laning and will usually hit at least one of his clones.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Night Stalker
* Heroes with low mobility that rely on spells: Zeus, Lina, Crystal Maiden.
Io
* Heroes that can easily bypass Io's allies to get to Io: Riki, Tusk, Clinkz, Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker, Lifestealer.
Night Stalker
* Durable heroes can stand against Tusk during 1v1: Axe, Dragon Knight, Night Stalker, Centaur Warrunner, Wraith King and more.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Night Stalker
* Heroes with silence such as Riki, Silencer, or Night Stalker prevents Skywrath Mage from using his spells.
Io
* 
Strafe, 
Tar Bomb and 
Burning Barrage from Aghanim's Shard allow Clinkz to quickly kill Io due to its low armor.
* Clinkz iz a hero that very often goes for 
Orchid Malevolence, and its upgrade 
Bloodthorn. Alternatively, Clinkz also loves to buy 
Gleipnir. And if Clinkz has both of them, he will be able to root and silence Io and prevent him from escaping with either Tether or Relocate.
Night Stalker
* The long silence at night prevents Clinkz from escaping with invisibility if Night Stalker can sneak up on him. He also has really low base health, so Night Stalker can usually kill him alone during one cast of Crippling Fear at night.
Io
* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:Crystal Maiden, Pugna, Skywrath Mage, Io, Witch Doctor, etc.
Night Stalker
* Night Stalker's Crippling Fear at night prevents Shadow Walk for an extended period of time and his Void will make Phase Boots useless. If Night Stalker has True Sight, he can shutdown Bounty Hunter's sneak kill.
Io
* 
Duel is very effective against Io due to its low health and armor.
Io
* Tethered heroes are much harder for Legion Commander to kill in Duels.
* Relocate can cancel Duels and save allies.
Io
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.
Night Stalker
* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.
Io
* Disruptor can always Glimpse back Io or his target after he Relocated nearby.
* Even better, thanks to the indicator on the ground, you can even preemptively drop Static Storm and Kinetic Field on the spot they will relocate to.
* Thunder Strike and Glimpse are also good tools to bring back an Io that Tethered away in the fog of war.
Additional:
* 
Glimpse directly negates Relocate.
* 
Kinetic Field prevents Io from escaping with Tether.
* 
Static Storm can silence and damage both, Io and it's tethered target. And it can also mute both, Io and it's tethered target when upgraded with Aghanim's Scepter.
Night Stalker
* May effortlessly get to and take down Disruptor.
* Void deals heavy single target damage and slow. Lacking innate escape mechanisms justs puts Disruptor in trouble
* Crippling Fear silences, and Disruptor is extremely dependant on abilities to work and to fend for himself.
* Hunter in the Night provides Night Stalker movement speed, attack speed and strengthens his abilities during night time, allowing him to easily catch up and obliterate Disruptor
* With Black King Bar, it's mostly assured to target down Disruptor.
Night Stalker
* Heroes with stronger lane presence that can threaten to kill him: Batrider, Juggernaut, Ursa, Monkey King, Razor.
Io
* Heroes with abilities that can save teammates are also effective such as Shadow Demon, Dazzle, Oracle, Bane, Pugna, Tusk, Winter Wyvern, Io, 
Underlord, 
Treant Protector and 
Keeper of the Light.
Night Stalker
* Mirror Image can be effective since Night Stalker cannot withstand fighting illusions. If he's unable to tell which Naga Siren is real, he will have a hard time landing his
Void. However, if Night Stalker obtains an 
Aghanim's Scepter, the upgraded Void will hit and may even locate the real Naga Siren in fights.
Ensnare and 
Song of the Siren prevents Night Stalker from escaping and ganking during daytime or even nighttime.
Rip Tide reduces Night Stalker's armor, making him easier to focus down.
Mirror Image can be effective against Night Stalker, due to his single target abilities.
Additional:
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*
*
Io
*
Ensnare and 
Song of the Siren can be used to cancel both, 
Tether and 
Relocate and to close the distance on Io.
Rip Tide combined with illusions from 
Mirror Image often finish off Io before he can save himself with 
Tether or 
Relocate.
Spirits's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from 
Mirror Image.
Aghanim's Scepter, she can gain access to 
Reel In, which not only allows her to cancel both, 
Tether and 
Relocate, but also to pull Io to herself and her team while he is affected with 
Ensnare, similarly to Batrider's 
Flaming Lasso.
Aghanim's Shard upgraded 
Song of the Siren can also heal the hero Io and his 
Tethered targed try to gank.
Ensnare and 
Song of the Siren can be used to cancel both, Tether and Relocate and to close the distance on Io.
Rip Tide combined with illusions from 
Mirror Image often finish off Io before he can save himself.
Mirror Image.
Aghanim's Scepter, she can gain access to 
Reel In, which not only allows her to cancel both, Tether and Relocate, but also to pull Io to herself and her team while he is affected with 
Ensnare, similarly to Batrider's 
Flaming Lasso.
Aghanim's Shard upgraded 
Song of the Siren can also heal the hero Io and his tethered targed try to gank.
*
*
* Once Naga Siren buys
*
Additional:
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*
* Spirit's weak area-of-effect makes it a bad tool to deal with Naga Siren's illusions from
* Once Naga Siren buys
*