* Any hero that can nullify effects of Chronosphere: (Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.

* Fate's Edict prevents Legion Commander from attacking for a few seconds, potentially saving Oracle's ally.
* Fortune's End dispels Press the Attack's healing and attack speed buff, as well as the movement speed bonus from Overwhelming Odds.
* False Promise protects allies and prevents Legion Commander from winning Duels and gaining bonus damage.
Additional:
* Provided that the enemy team does not have an Axe, Oracle can guarantee that his ally survives for the duration of the Duel with False Promise and has decent nuke potential to help ally to win a Duel. He can also disarm Legion Commander with Fate's Edict.
* Oracle can dispel enemy buffs like Overwhelming Odds and Press the Attack with Fortune's End.

* Nyx Assassin might not kill Abaddon with his nuke, but a support Abaddon will struggle to protect an ally from him.

* Oracle with Fortune's End and False Promise
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Heroes with abilities that can save teammates are also effective such as Shadow Demon, Dazzle, Oracle, Bane, Pugna, Tusk, Winter Wyvern, Io, Underlord, Treant Protector and Keeper of the Light.

* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity, even if Batrider is focusing on other enemy hero.

* False Promise dispels Flaming Lasso.
* Fortune's End can root Batrider after he uses Flaming Lasso. It can also dispel Sticky Napalm and Flamebreak.
* Fate's Edict when used on a Lasso'd target will leave them immune to magical damage, making it difficult to burst them quickly before the Lasso ends.

* The huge physical damage taken from Vendetta will force Necrophos to use Ghost Shroud, which is good for a followup with Dagon and Ethereal Blade, both of which are common items on Nyx Assassin.
* Using Ghost Shroud also sets Necrophos up for a Mind Flare or Impale.

* During the laning stage, Oracle's Purifying Flames nullifies any damage that Heartstopper Aura might inflict.
* Fate's Edict and False Promise can protect an ally from Reaper's Scythe.
* Oracle can dispel Ghost Shroud with Fortune's End.
Additional:
* Fortune's End can dispel Ghost Shroud, negating the skill's utility. Also it's worth noting that Necrophos takes additional magic damage when in Ethereal state, which makes Purifying Flames a powerful nuke against him.
* Fate's Edict fully negates the damage from Reaper's Scythe, which its own delayed animation makes it relatively easy to predict and nullify.

* Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel Life Drain, making him easy to hit with Impale.
Additional:
* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mind Flare will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.

* All of Pugna's damage is magical, which can get blocked by Fate's Edict's 100% magic resistance.
* Oracle has two abilities that apply a dispel, which can easily remove Decrepify on his ally or Oracle.

* Spiked Carapace reacts on any of the damage over time from Phoenix's abilities and can interrupt Sun Ray and Icarus Dive.

* Phoenix does significant magic damage over time which can either be dispelled or negated by Fate's Edict.
* Oracle's burst damage potential can prove lethal to Phoenix, as they already have to sacrifice health to cast their basic skills.

* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.

* Fortune's End not being disjointable is almost an ensured disable if Dark Willow tries to escape with Shadow Realm. Dispels Cursed Crown and Terrorize.
* Fate's Edict negates all her magic damage in case she catches a single hero.
* False Promise's strong dispel removes Dark Willow's disables.
Additional:
* Fortune's End can easily dispel Cursed Crown before it times out and stuns. He can also save a stunned ally with False Promise.
* Fate's Edict can easily negate Bedlam's over-time damage, since the spell provides no form of control. Similarly, he can also negate the magic burst from Shadow Realm.
* Fortune's End can dispel the fear effect from Terrorize, and it can remove the root from Bramble Maze if cast quick enough. Be mindful that Fortune's End only dispels your allies' debuffs on the primary target.

* Nyx Assassin's Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* Mind Flare deals high damage due to Leshrac's high intelligence gain.
* Vendetta burns a large amount of Leshrac's essential mana pool.

* Oracle's Fate's Edict will protect an ally from Leshrac's nuking damage.
* Oracle's False Promise can dispel Leshrac's stun and slow from his abilities, allowing an ally to escape.
* Fortune's End can stop Leshrac from chasing opponents or running away.

* Vendetta can deal great damage against her. However, it requires an direct attack, so Nyx Assassin may have difficulties applying Vendetta on her.
* Enchantress's lack of mobility makes her a primary target for ganking with Vendetta.
* Mind Flare can deal a great damage against her due to being an Intelligence hero.
* Spiked Carapace can reflect Impetus and stun Enchantress.
Additional:
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.

* Heroes with little health or magic resistance are easily picked off with Oracle's magic burst, such as Skywrath Mage, Crystal Maiden, or Enchantress.

* Assassinate is easy to reflect with Spiked Carapace for massive damage.
* Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.

* Fortune's End can catch out or impair position-based heroes with low mobility, such as Sniper or Razor.

* Crystal Maiden has a very bad movement speed, so Impale is easy to land against her. Furthermore, even while trapped by Frostbite, Nyx Assassin can still cast Impale.
* Crystal Maiden has very low armor, so Vendetta is very effective.
* Nyx Assassin has two ways to stop Freezing Field, provided she doesn't get a Black King Bar. He can either pop Spiked Carapace and simply walk into the field, or he can use Impale to interrupt the field, since Crystal Maiden has to channel it.
Additional:
* Spiked Carapace easily interrupts Freezing Field.
* Frostbite's damage over time sets up an easy Spiked Carapace stun.
* Crystal Maiden is extremely fragile and dies quickly to Nyx Assassin's burst damage.

* Heroes with little health or magic resistance are easily picked off with Oracle's magic burst, such as Skywrath Mage, Crystal Maiden, or Enchantress.

* Spiked Carapace can be used to reflect Illuminate damage and stun Keeper of the Light.
* Vendetta allows Nyx Assassin to follow Keeper of the Light around if he tries to split-push.
* Keeper of the Light is very squishy and will very quickly die to Vendetta and it's followup abilities.

* Heroes with dispels: Legion Commander, Oracle, Slark, Phantom Lancer

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* Oracle can negate and shut down Primal Beast simply with Fate's Edict, especially in the early game, as a majority of his damage-dealing spells are magic.
* Oracle can interrupt Primal Beast's Onslaught charge with a well-timed Fortune's End.
* Primal Beast's lethal burst damage combos can be further stalled with False Promise; combined with Fate's Edict and regen from Purifying Flames, Oracle can even completely negate Primal Beast's offense.
Additional:
* Fate's Edict completely negates all of Primal Beast's major damage-dealing spells in the early game and can render Primal Beast useless when cast on a target he is focusing, or in Oracle's defense against Primal Beast himself.
* Fortune's End keeps Primal Beast in place, especially while trampling or in the middle of an Onslaught charge.
* False Promise can interrupt Primal Beast's abilities, as well as further delay Primal Beast from dealing lethal burst damage. In combination with Fortune's End, Oracle can potentially save an ally from Primal Beast's spell combos.

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* False Promise can dispel the stun from Cold Feet and can save an ally that's about to shatter from Ice Blast, even allowing healing with Purifying Flames by delaying it until after the debuff expires.
* Purifying Flames allows Oracle to deny his allies if they're affected by Ice Blast. If he brings his allies' health to or below the shatter threshold, it will count as him denying the ally. However, this does not work on Oracle himself.
* Fate's Edict provides 100% magic resistance, making it good against all of Ancient Apparition's abilities at all stages of the game.
* Fortune's End can dispel Cold Feet from allies.
Additional:
* False Promise can prevent the shatter from Ice Blast and Fate's Edict can protect an ally from the magical damage over time for a while.
* Oracle can deny allies who are frostbitten. If he uses Purifying Flames to reach the shatter threshold, it will count as a deny.
* Fortune's End can dispel Cold Feet on affected allies, preventing them from getting frozen.

* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos

Additional:
* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* Mind Flare turns Skywrath Mage's high intelligence growth against him and deals heavy damage.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.

* Fate Edict can completely negate Skywrath Mage's heavy magic damage.
* Fortune End dispels Ancient Seal.

* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin.

* Fortune's End's AoE dispel will remove Heavenly Grace and Guardian Angel.
Additional:
* Oracle can dispel Heavenly Grace (which he can also bait out with Fate's Edict).
* With Fortune's End, Oracle can dispel Guardian Angel in an area of effect.

* With Vendetta, Nyx Assassin can move closely to Ember Spirit when he's farming with his Flame Guard and use Spiked Carapace with Impale to provide a reliable and long disable.
Additional:
* Spiked Carapace can be easily triggered by Flame Guard or Battle Fury, setting up a deadly Impale.

* Oracle can shut down both of Ember's early game abilities. Fortune's End can dispel Flame Guard on Ember Spirit and Searing Chains on allies.
* When Ember Spirit is affected by Fortune's End, his Fire Remnants move at 0 movement speed.
* Disarming him with Fate's Edict does affect Ember's Sleight of Fist ability, possibly making him useless for a few seconds in the late game without a dispel or spell immunity. This is especially good if he has a rapier or two. However, positioning for this is difficult when Ember plays far back.

* Heroes with heavy early and mid-game magical damage are also problematic for Phantom Assassin due to being able to easily kill her before she can gain an item advantage over them: Lina, Necrophos, Nyx Assassin, Gyrocopter, Jakiro, Death Prophet.

* Fate's Edict cripples many heroes who rely on attacks, such as Phantom Assassin, Sven, or Enchantress, without a dispel or a Black King Bar.

* False Promise effectively nullifies Primal Roar's single-target initiation on allies.
* Purifying Flames kills Beastmaster's Hawk instantly and Boar with two casts.

* Spiked Carapace stops Snapfire's Mortimer Kisses.

* Nyx Assassin deals large amounts of pure damage with Vendetta and magical damage with Impale and Mind Flare, allowing him to ignore Terrorblade's armor and burst his low health pool down before he can use Sunder.
* Nyx Assassin commonly buys Urn of Shadows, Dagon and Meteor Hammer which deal magic damage that ignore Terrorblade's armor.
* However, Terrorblade is a natural Eye of Skadi and Black King Bar wielder, and once he gets those items, Nyx Assassin's solo kill potential against Terrorblade will be gone.

* Nyx Assassin's high burst damage, excellent ganking potential and multiple disables pose a threat to Muerta at all stages of the game.
* Mind Flare allows Nyx Assassin to take advantage of Muerta's high intelligence and make a short work of her low health.
* Spiked Carapace and Vendetta allow Nyx to escape or initiate well against Muerta's low mobility.
* As with most retaliation based abilities, Spiked Carapace can easily take advantage of Gunslinger's stray shots.
* However, Muerta is a natural Black King Bar wielder. And if she succeeds to activate it before Nyx Assassin can ambush her, he will go down very quickly against Muerta as Spiked Carapace cannot pierce through debuff immunity at all.

* Nyx Assassin can simply activate Spiked Carapace while under many Invoker's abilities to stun him.
* Nyx Assassin takes advantage of Invoker's massive intelligence gain to do tons of damage using Mind Flare, as the spell does more damage based on the target's intelligence.
* Vendetta burns a large amount of Invoker's essential mana pool.

* Nyx's Spiked Carapace can reflect the damage of Sharpshooter, instantly killing hoodwink. Nyx can also use Vendetta to position himself in such a way to screen allies from Sharpshooter and catch Hoodwink by surprise.

* Illusory Orb is easy to reflect with Spiked Carapace, either stunning Puck and setting up an easy Impale or forcing a premature Phase Shift.
* Puck is an intelligence hero that tends to build intelligence items, making it vulnerable to Mana Burn.
* An ill-timed Phase Shift can easily set Puck up to be stunned by Impale.
* Puck's low base armor and below average agility gain mean it is always susceptible to Vendetta.
Additional:
* Nyx Assassin can take advantage of every one of Puck's weaknesses. His entire skill set is very effective in countering Puck.
* Because Illusory Orb is such a slow moving projectile, Nyx Assassin can simply walk into the orb and activate Spiked Carapace, stunning Puck and setting up an easy Impale. This can be circumvented by using Phase Shift while the orb is traveling, however, that means that Puck cannot use Phase Shift to dodge any other skill nor use it to safely blink away from a fight.
* Puck is an intelligence hero that likes to build intelligence items such as Eul's Scepter of Divinity, Scythe of Vyse, and Dagon. This makes Mind Flare that much more deadly against Puck.
* An ill-timed Phase Shift can turn into an easy setup for Impale.

* Oracle's high magic damage output can easily take down Rubick's low health pool.
* Because Oracle can combo spells in rapid succession (due to low cooldowns), it may be difficult for Rubick to Spell Steal False Promise. This scenario can even be avoided by shift queueing Fortune's End and casting it immediately, as it has no cast point, or by staying in the back line of fights if out of mana.
* As a position based hero, Rubick will have a very hard time against Fortune's End due to its absurd range and very long root duration.

* Mana Burn removes much-needed mana for Ball Lightning.
* Spiked Carapace triggers on Static Remnant for an easy stun.
Additional:
* Vendetta is capable of removing most of Storm Spirit's large mana pool, along with dealing heavy damage and quickly depleting his chances of escaping a gank or fight.

* Impale and Spiked Carapace can be used to cancel Dismember easily, and can even do so when Pudge uses it on Nyx Assassin, if timed correctly.

* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.

* Nyx Assassin has a lot of burst damage from his Impale, Mind Flare, Dagon, and the bonus damage from Vendetta. All of this damage is enough to kill Drow Ranger.
* Nyx Assassin is usually invisible most of the time thanks to his ability Vendetta, which allows him to gank Drow Ranger easily.
* However, Gust is extremely dangerous for Nyx Assassin, as it's silence can render Nyx Assassin unable to lock down Drow Ranger. And if Gust hits Nyx Assassin while he is invisible with Vendetta, Drow Ranger will be able to detect him and foil his ganking attempts on her because Gust reveals invisible units.

* Last Word is extremely easy to reflect with Spiked Carapace for large amounts damage, due to triggering when Nyx Assassin casts a spell, but can still silence Nyx Assassin. It also has the added bonus of dealing more damage the more Intelligence Silencer has.
* Glaives of Wisdom quickly builds Silencer's Intelligence, making him a particularly prime target for Mana Burn.
* Silencer rarely builds survivability items, nor is he able to steal much Intelligence while surrounded by his team, and so is an excellent target for Vendetta.
* Silencer has no reliable way of dealing with a burrowed Nyx, and also lacks the ability to prevent Nyx from escaping with Vendetta,
Additional:
* Silencer is rather squishy and has poor mobility without items, making him an easy target for Nyx.
* Silencer's intelligence steal ability is a complete disadvantage against Nyx Assassin as Mind Flare will deal increasing damage for each point of intelligence Silencer has stolen, turning Silencer's intelligence steal against him.

* Fortune's End can nullify Arcane Curse, Last Word, and Global Silence, if cast at the right time with the right targets.
* Fate's Edict can prevent Silencer from attacking, which he relies on with Glaives of Wisdom, for a lot of his damage.

* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with Spiked Carapace.
* Vendetta can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.

* Spiked Carapace allows Nyx to get an easy long-duration stun on Weaver once he uses Shukuchi, and then he can follow up with Impale.
* Vendetta works as a great setup for both Impale and Spiked Carapace and can deal decent damage to Weaver. Additionally he can neutralize The Swarm beetles due to his invisibility duration.

* Many of Nyx Assassin's abilities are good against Windranger.
* Impale is great for stunning Windranger and allowing additional disables to be landed.
* Mind Flare is useful against Windranger's decent intelligence growth.
* Spiked Carapace is easy to use against Powershot.
* Vendetta allows Nyx Assassin to sneak up on and deal massive damage to Windranger without giving Windranger a chance to use Windrun to evade it.
* Nyx Assassin's item build allows him to easily deal with Windranger.

* Fate's Edict gives full immunity from Ogre Magi's mostly magical damage.
* Fortune's End can dispel Ignite (when used on allies) and Bloodlust (when used on enemies).
* False Promise can dispel Ignite and Fireblast.

* Impale and Spiked Carapace interrupts Upheaval with ease.
* Warlock's low health pool, mobility, and high intelligence gain makes him a prime target for Nyx Assassin's burst damage.

* Fortune's End dispells Marci's Sidekick, removing additional damage and lifesteal.
* Fate's Edict disarms Marci, preventing her from attacking with Unleash. Also it is useful against Marci or her ally affected by Sidekick.
* False Promise is a great tool to save an ally focused by Marci.

* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed Sanity's Eclipse and/or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used Black King Bar beforehand.
Additional:
* Outworld Destroyer's high intelligence makes him a good target for Mind Flare.
* If timed correctly, Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.

* Vendetta disables Vengeance Aura and allows him to attack Vengeful Spirit with Impale and Mind Flare.
* Spiked Carapace is easy to use against a Wave of Terror or Magic Missile.

* Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.

* Heat-Seeking Missile allow easy Spiked Carapace stuns.
* As a fragile hero that relies on mana and intelligence items, Tinker is vulnerable to Mana Burn.
* Nyx Assassin's stuns can interrupt Rearm and leave Tinker helpless.
Additional:
* Nyx Assassin's whole skillset is good against Tinker:
* Impale prevents Tinker from blinding Nyx Assassin or fighting back, while giving Nyx' allies time to catch up to Tinker's position.
* Mind Flare generally deals more damage to intelligence based heroes like Tinker.
* Spiked Carapace can stun Tinker at a moment of Nyx Assassin's choosing if March of the Machines has been cast. It is also quite easy to time Spiked Carapace against Heat Seeking Missiles.
* Vendetta allows Nyx to approach Tinker in the trees or wait for him in common hiding spots and deal heavy damage to his low armor.

* Heroes with either magical, physical or pure damage burst can often kill Chen or his allies before he can use Hand of God: Lina, Luna, Techies, Shadow Fiend, Pugna, Nyx Assassin.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin.

* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light, Dawnbreaker.

* Fortune's End can catch out or impair position-based heroes with low mobility, such as Sniper or Razor.

* Heroes that can pick you off: Clinkz, Nyx Assassin, Puck, Riki.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Heroes that can purge his slow and disables are very difficult to go on and their team: Abaddon, Oracle.

* Heroes with strong dispels can dispel Bane's disables from their allies: Oracle, Legion Commander, Omniknight.

* Fate's Edict cripples many heroes who rely on attacks, such as Phantom Assassin, Sven, or Enchantress, without a dispel or a Black King Bar.

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill Shadow Shaman, Nyx being particularly deadly. Shadow Shaman must watch out for Slark carefully, as he can break either (but not both unless he makes a mistake) of Shadow Shaman's disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn Shadow Shaman from prey to predator.

* Heroes with area dispel can kill multiple skeletons at once: Brewmaster, Oracle.

* Heroes with magical or pure damage output will not have any problems against Atrophy Aura at all: Luna, Lina, Jakiro, Pugna, Bane, Snapfire, Muerta, Nyx Assassin, Enigma, Tinker, Witch Doctor, Zeus, Crystal Maiden.

* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.

* Oracle can negate all of Techies' skills with Fate's Edict, as they are all magic damage. Fate's Edict can also be used to search and trigger Proximity Mines when crossing mined territory.
* Oracle can dispel Reactive Tazer off Techies, as well as the silence from Blast Off!, with Fortune's End.
* Oracle can further delay Techies' burst damage capability with False Promise.
Additional:
* Fate's Edict gives 100% magic resistance, which prevents most of Techies' damage.
* Oracle's Fortune's End dispels Reactive Tazer buff from Techies allowing him to be attacked. However, Reactive Tazer will instantly perform the area of effect disarm that is normally applied at the end of the duration.
* Fortune's End will also dispel Blast Off silence, Techies' Etheral Blade, Proximity Mines' magic resistance reduction, and Sticky Bomb's slow. However beware that it will only dispel Sticky Bomb's first or second instance of slow and not the damage, which will trigger as normal.

* Spiked Carapace can stop Dawnbreaker's Solar Guardian which will eliminate her global presence and limits her movement around the map.
Additional:
* Spiked Carapace interrupts Starbreaker before Dawnbreaker has her Aghanim's Shard, as well as Solar Guardian during the initial channel, making her ineffective at joining and dealing damage in teamfights.
* The slow projectile and damage over time effect of Celestial Hammer makes it easy to stun Dawnbreaker if she attemps to engage or chase.

* Fate's Edict allows Oracle to make allies spell immune, allowing him to save allies from Jakiro's spells.
* Fate's Edict can be cast onto Jakiro to disarm him and prevent him from pushing with his Liquid Fire.
* False Promise allows Oracle to free allies from Jakiro's Ice Path.

* Fate's Edict can disarm Troll, rendering him useless in a teamfight, especially if he has already used Battle Trance.
* Fortune's End and Purifying Flames can provide ample magic damage to help burst down Troll Warlord quickly in the early to mid game.
* False Promise can save an ally from Troll Warlord's initiation, forcing him to switch targets and lose his Fervor stacks, or waste time during Battle Trance.

* It is especially easy for Oracle to negate the damage from Maledict, and even heal through it with Fate's Edict and Purifying Flames.
* If by some miracle an enemy is still about to die because of Maledict, he can still save him with False Promise.

* Mind Flare does tons of damage against Lina because of her high intelligence.
* Vendetta can deal heavy damage to Lina while also burning her mana, preventing Lina from casting her abilities.
* Spiked Carapace can easily be used to counter Lina's abilities because of their long cast animation, and could probably kill Lina outright if Laguna Blade is reflected. However, Lina can counter this with Eul's Scepter of Divinity, a common item on Lina.

* Fortune's End dispels Ion Shell and Surge, making any gank attempt on Dark Seer in the laning phase likely to succeed.
* Fate's Edict prevents all magical damage that comes from Dark Seer's abilities.
* Fortune's End dispels Ion Shell on creeps, which Dark Seer relies on to farm and zone.
Additional:
* Fortune's End can dispel Ion Shell, a skill that helps Dark Seer immensely in the laning phase, as well as Surge, a move-speed buff, effectively allowing Oracle to control Dark Seer, especially in the laning phase.

* Fortune's End and False Promise easily dispel many crippling debuffs, such as Venomancer's Venomous Gale, or Skywrath Mage's Ancient Seal.

Additional:
* Fortune's End can dispel Venomous Gale and Poison Sting from allies.
* Fate's Edict grants 100% magic resistance to target, inhibiting the damage from Venomancer abilities.

* Lion is extremely dependent on his abilities. Silences like Silencer's Last Word, magic resistance like Oracle's Fate's Edict, and dispels like Legion Commander's Press the Attack all make his abilities less effective.

* Nyx Assassin can reflect Life Break with Spiked Carapace.

* Fortune's End applies a basic dispel which can be used to dispel Corrosive Haze, or even Slardar's own Guardian Sprint.
* False Promise is able to dispel Corrosive Haze and Slithereen Crush stun/slow from any allies Oracle chooses to cast it on.
* Fate's Edict can also be cast on Slardar to prevent him from proccing his Bash of the Deep.

* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Luna, Puck, Slark, Nyx Assassin, etc.

Additional:
* Enigma's uncontrollable damage from Malefice and Midnight Pulse make him easy to stun with Spiked Carapace.
* Black Hole can be easily interrupted by Impale or Spiked Carapace.