* Heroes with AoE abilities will hit Slark in Shadow Dance: Lina, Jakiro, Underlord, Leshrac, Dark Seer, Earthshaker, Timbersaw, Crystal Maiden.

Additional:
* Timbersaw can use Chakram as a scouting tool to find Slark if he tries to Pounce into the trees.
* None of Timbersaw's abilities require a target to be cast, allowing him to hit Slark inside Shadow Dance.
* Reactive Armor can be effective protection against a Slark who attacks quickly, since the strong armor and health regen cannot be stolen by Essence Shift.
* Timber Chain makes Timbersaw very mobile, meaning he is among the very few heroes who can actually give chase to a fleeing Slark.

* Spiked Carapace can be easily triggered by Flame Guard or Battle Fury, setting up a deadly Impale.
Additional:
* With Vendetta, Nyx Assassin can move closely to Ember Spirit when he's farming with his Flame Guard and use Spiked Carapace with Impale to provide a reliable and long disable.

* Nyx Assassin might not kill Abaddon with his nuke, but a support Abaddon will struggle to protect an ally from him.

* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill Shadow Shaman, Nyx being particularly deadly. Shadow Shaman must watch out for Slark carefully, as he can break either (but not both unless he makes a mistake) of Shadow Shaman's disables, with Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn Shadow Shaman from prey to predator.

* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos

Additional:
* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* Mind Flare turns Skywrath Mage's high intelligence growth against him and deals heavy damage.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.

* Special mention to Timbersaw as he has a way to deal with Axe in the laning stage, but still needs to be careful about Berserker's Call stun, the pure damage from Counter Helix and Culling Blade finishing him off before he can escape or heal from his passive.

Additional:
* Whirling Death reduces Axe's strength by 15%, which makes him less durable, especially from early game. It's also stackable.
* Blade Mail are not effective against attribute changes, and Timber Chain can wait out Blade Mail's duration to wear off.
* Reactive Armor makes it harder for Axe to finish off Timbersaw with Culling Blade.
* Chakram disarms Timbersaw, which makes Axe's Counter Helix useless against him.
* All Timbersaw skills deal pure damage, which bypass Axe's high armor or bonus armor from Berserker's Call.

* Nyx Assassin deals large amounts of pure damage with Vendetta and magical damage with Impale and Mind Flare, allowing him to ignore Terrorblade's armor and burst his low health pool down before he can use Sunder.
* Nyx Assassin commonly buys Urn of Shadows, Dagon and Meteor Hammer which deal magic damage that ignore Terrorblade's armor.

* Timbersaw can take down Terrorblade's illusions with his area damage burst.
* Reactive Armor plus another armor item reduce much of Terrorblade's damage.
Additional:
* Timbersaw's abilities combos all deal magical and pure damage, completely ignoring Terrorblade's high base armor and clearing his illusions very quickly due to the AoE damage.
* Reactive Armor negates most of Terrorblade's damage against Timbersaw, and its high health regeneration and armor bonuses can help Timbersaw survive after Terrorblade has used Sunder on him.

* Impale and Spiked Carapace can be used to cancel Dismember easily, and can even do so when Pudge uses it on Nyx Assassin, if timed correctly.

* The percentage-based primary-attribute reduction effect of Whirling Death can be devastating for Pudge due to his high strength gain through Flesh Heap.
* Reactive Armor's health regeneration and common itemization for magic resistance and durability makes Timbersaw a poor target for Pudge.
* Timber Chain's high mobility makes it difficult for Pudge to hook or deal much Rot damage to Timbersaw.

* Nyx's Spiked Carapace can reflect the damage of Sharpshooter, instantly killing hoodwink. Nyx can also use Vendetta to position himself in such a way to screen allies from Sharpshooter and catch Hoodwink by surprise.

* Timbersaw’s reliance on nearby trees means he’ll usually be close to Hoodwink.
* More significantly, Timbersaw's tree destroying abilities cut off Hoodwink's escape options, passive and easily foil Acorn Shot or Bushwhack combos.
* While channeling Sharpshooter, Timbersaw can simply sit his Chakram on top of her and unleash his full combo, forcing her to cancel and disengage.
* Timber Chain can be used to dodge Sharpshooter.

* Heroes with heavy early and mid-game magical damage are also problematic for Phantom Assassin due to being able to easily kill her before she can gain an item advantage over them: Lina, Necrophos, Nyx Assassin, Gyrocopter.

* Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger.
* Phantom Assassin has a moderate health pool and usually appears in the front line of battle, making her vulnerable to Timbersaw's magic burst.
* Timbersaw can easily escape from Phantom Assassin thanks to his Timber Chain.
Additional:
* Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger, as well as ganking attempts.
* Phantom Assassin is a hero with moderate HP pool, and usually appears in the front line of battle. Because Blur does nothing against spells, she is vulnerable to Timbersaw's skills.
* Timbersaw can easily escape from Phantom Assassin thanks to his Timber Chain.

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin.

* All three of Timbersaw’s abilities give him an easy way out of Sprout, and can also destroy nearby trees so Nature's Prophet can’t spawn Treants.
* If Prophet tries to escape with a self Sprout/Teleport, Timbersaw can easily cut down all its trees to get to him and deal increased Whirling Death damage as well.
* Chakram heavily discourages teleports.
* Timbersaw is quite well suited to clearing massive waves of Treants almost instantly with all of his area of effect pure damage abilities, preventing Nature's Prophet from pushing.
* Treants can give Reactive Armor many charges quite quickly.
Additional:
* Timbersaw can easily cut down trees from Sprout, making it very difficult for Nature's Prophet to teleport away or trap enemies.
* Timbersaw's abilities quickly clear out treants.
* Reactive Armor negates most of the damage of Nature's Prophet's treants, and Timbersaw can often allow himself to be attacked in order to heal himself.

* Heroes with either magical, physical or pure damage burst can often kill Chen or his allies before he can use Hand of God: Lina, Luna, Techies, Shadow Fiend, Pugna, Nyx Assassin.

* With Timber Chain, Timbersaw can slow, catch up with, or escape from Chen and his creeps.
* Chakram and Flamethrower from Aghanim's Shard can clear Chen's creeps and slow him.
* Attacks from multiple creeps will quickly build Reactive Armor stacks, making attacks of Chen and his creeps only tickle Timbersaw.

* Vendetta can deal great damage against her. However, it requires an direct attack, so Nyx Assassin may have difficulties applying Vendetta on her.
* Enchantress's lack of mobility makes her a primary target for ganking with Vendetta.
* Mind Flare can deal a great damage against her due to being an Intelligence hero.
* Spiked Carapace can reflect Impetus and stun Enchantress.
Additional:
* Spiked Carapace reflects the damage from Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.

* The burst damage from Timbersaw's abilities is more than enough to deal with Enchantress and her creeps.
* Timbersaw doesn't rely on his physical attacks, which makes Untouchable useless against him.
* Since Timbersaw purchase Lotus Orb, Enchant target to Timbersaw's is not efective and impacting reflect Enchantress affected movement speed useless slow too.
* Timber Chain can close the gap between them and minimize damage from Impetus.
* Bear in mind, however, that Timber Chain can also work against Timbersaw if used to escape and that Impetus can ignore Reactive Armor if Enchantress is not a primary target for Timbersaw or if he is disabled.

* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity, even if Batrider is focusing on other enemy hero.

* Spiked Carapace stops Snapfire's Mortimer Kisses.

* Reactive Armor is very effective against Beastmaster's summons during laning stage and entire game.
* Timbersaw can quickly clear Beastmaster's summons with his nukes.
* Lotus Orb item for Timbersaw can difficult for Primal Roar.

* With her passive Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious Stone Gaze.
* Mana Burn quickly destroys Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Additional:
* Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.

* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with Spiked Carapace.
* Vendetta can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.

* Timbersaw can easily cut down the tree that Monkey King is standing on, stunning him for a lengthy period.
* Timbersaw can use Timber Chain to easily escape Wukong's Command and Primal Spring's slow.
Additional:
* Timbersaw's low cooldown and low mana cost abilities destroys the trees that Monkey King depends on.
* Timber Chain allows Timbersaw to escape Wukong's Command.

* Crystal Maiden has a very bad movement speed, so Impale is easy to land against her. Furthermore, even while trapped by Frostbite, Nyx Assassin can still cast Impale.
* Crystal Maiden has very low armor, so Vendetta is very effective.
* Nyx Assassin has two ways to stop Freezing Field, provided she doesn't get a Black King Bar. He can either pop Spiked Carapace and simply walk into the field, or he can use Impale to interrupt the field, since Crystal Maiden has to channel it.
Additional:
* Spiked Carapace easily interrupts Freezing Field.
* Frostbite's damage over time sets up an easy Spiked Carapace stun.
* Crystal Maiden is extremely fragile and dies quickly to Nyx Assassin's burst damage.

* Many of Nyx Assassin's abilities are good against Windranger.
* Impale is great for stunning Windranger and allowing additional disables to be landed.
* Mind Flare is useful against Windranger's decent intelligence growth.
* Spiked Carapace is easy to use against Powershot.
* Vendetta allows Nyx Assassin to sneak up on and deal massive damage to Windranger without giving Windranger a chance to use Windrun to evade it.
* Nyx Assassin's item build allows him to easily deal with Windranger.

* Nyx Assassin has a lot of burst damage from his Impale, Mind Flare, Dagon, and the bonus damage from Vendetta. All of this damage is enough to kill Drow Ranger.
* Nyx Assassin is usually invisible most of the time thanks to his ability Vendetta, which allows him to gank Drow Ranger easily.

* Assassinate is easy to reflect with Spiked Carapace for massive damage.
* Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.

* Whirling Death deals damage while also reducing {Show:A|Timbersaw|Whirling Death|value4} of Bristleback's strength, making him less tanky.
* Reactive Armor can sustain through multiple Viscous Nasal Goo and Quill Spray stacks.
* Timber Chain makes it hard for Bristleback to slow down Timbersaw even with Viscous Nasal Goo.

* Timbersaw is often too mobile and durable for Gyrocopter to bring down with his area attacks.

* Spiked Carapace reacts on any of the damage over time from Phoenix's abilities and can interrupt Sun Ray and Icarus Dive.

* Vendetta disables Vengeance Aura and allows him to attack Vengeful Spirit with Impale and Mind Flare.
* Spiked Carapace is easy to use against a Wave of Terror or Magic Missile.

* Impale and Spiked Carapace interrupts Upheaval with ease.
* Warlock's low health pool, mobility, and high intelligence gain makes him a prime target for Nyx Assassin's burst damage.

* Timbersaw relies on dealing massive amounts of pure damage, making Cold Embrace a good setup for his nukes.
* If he has Reactive Armor stacks, Timbersaw can tank the damage from his allies if he is targeted by Winter's Curse. If he's not the target, Timbersaw's abysmal attack damage will contribute next to nothing when he is cursed to attack an ally.
* Since Timbersaw build Lotus Orb, Winter's Curse is very useless for Winter Wyvern makes reflected back taunted to herself and ganking.

* Strong area damage, particularly from Whirling Death and Chakram, lets Timbersaw clear out illusions quickly.
* Whirling Death directly reduces Strength from both Chaos Knight and his Phantasm illusions, reducing both the damage output and raw health that the hero relies on.
* Reactive Armor quickly builds stacks against Phantasm illusions, making Timbersaw hard to kill.
Additional:
* Reactive Armor helps Timbersaw to endure the damage from Chaos Bolt and Reality Rift combo.
* Timbersaw's large amount of pure damage AoE nukes clears Chaos Knight's illusions quickly, drastically reducing his damage.

* Timbersaw Defeats Kunkka on the center line, due to the fact that he has a huge resistance to physical damage by Reactive Armor, which is why Tidebringer almost does not break through Timbersaw, and due to Whirling Death Timbersaw can very much break through Kunkka and force him to leave the line, or spend money on Tango.
Additional:
* Timbersaw Defeats Kunkka on the center line, due to the fact that he has a huge resistance to physical damage by Reactive Armor, which is why Tidebringer almost does not break through Timbersaw, and due to Whirling Death Timbersaw can very much break through Kunkka and force him to leave the line, or spend money on Tango.

* Not only are all of Timbersaw's active abilities capable of cutting down trees, but Whirling Death and Timber Chain also require it to be effective, counteracting both Treant Protector's Nature's Guise and Eyes in the Forest abilities.
Additional:
* Timbersaw can use his plethora of tree cutting abilities to level entire sections of the forest, making hiding in the trees more difficult for Treant Protector and his team.
* Timbersaw can easily cut down Treant Protector's Eyes In The Forest once his team has detection. He may even do it unknowingly due to the sheer destructive and chaotic nature of his abilities.

* Because multiple Meepos tend to clump up, they present an easy target for Timbersaw's many area abilities.
* Although be careful since Timbersaw cannot use Timber Chain to escape if rooted from Earthbind.

* Heroes with high magical or pure damage will bypass Bulwark: Timbersaw, Dark Willow, Enigma, Invoker, Pugna, Skywrath Mage, Tinker, Zeus, Oracle.

* Heroes who rely on abilities to deal damage (e.g. Timbersaw, Tinker) can fight a Razor even after Static Link.

Additional:
* Razor deals mostly physical damage towards the later game, and Timbersaw is also very mobile, making him a difficult kill to earn.
* Timbersaw rarely resorts to attacks, thus does not suffer when his damage is stolen with Static Link.

* Heroes that can pick you off: Clinkz, Nyx Assassin, Puck, Riki.

* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light, Dawnbreaker.

Additional:
* Spiked Carapace can be used to reflect Illuminate damage and stun Keeper of the Light.
* Vendetta allows Nyx Assassin to follow Keeper of the Light around if he tries to split-push.
* Keeper of the Light is very squishy and will very quickly die to Vendetta and it's followup abilities.

* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.

* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin.

* Reactive Armor makes Timbersaw very effective against heroes that control a lot of units, such as Broodmother, Lycan and Undying.

* Nyx Assassin's whole skillset is good against Tinker:
* Impale prevents Tinker from blinding Nyx Assassin or fighting back, while giving Nyx' allies time to catch up to Tinker's position.
* Mind Flare generally deals more damage to intelligence based heroes like Tinker.
* Spiked Carapace can stun Tinker at a moment of Nyx Assassin's choosing if March of the Machines has been cast. It is also quite easy to time Spiked Carapace against Heat Seeking Missiles.
* Vendetta allows Nyx to approach Tinker in the trees or wait for him in common hiding spots and deal heavy damage to his low armor.
Additional:
* Heat-Seeking Missile allow easy Spiked Carapace stuns.
* As a fragile hero that relies on mana and intelligence items, Tinker is vulnerable to Mana Burn.
* Nyx Assassin's stuns can interrupt Rearm and leave Tinker helpless.

* Timbersaw's ability to destroy trees can be a serious problem for some heroes that use them, as either a way of enhancing their spells like Treant Protector, or heroes that tend to hide inside of them like Tinker and Monkey King.

* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, Skywrath Mage, Tinker, Ursa, Void Spirit.

* Heroes who are not easily crippled by Fate's Edict or Fortune's End, such as Timbersaw, or those who can dispel them, such as Phantom Lancer, can kill Oracle unhindered.

* Timbersaw: Lone Druid will have a hard time dealing with Timbersaw due to his tankiness and high Armor from Reactive Armor

* Nyx Assassin can take advantage of every one of Puck's weaknesses. His entire skill set is very effective in countering Puck.
* Because Illusory Orb is such a slow moving projectile, Nyx Assassin can simply walk into the orb and activate Spiked Carapace, stunning Puck and setting up an easy Impale. This can be circumvented by using Phase Shift while the orb is traveling, however, that means that Puck cannot use Phase Shift to dodge any other skill nor use it to safely blink away from a fight.
* Puck is an intelligence hero that likes to build intelligence items such as Eul's Scepter of Divinity, Scythe of Vyse, and Dagon. This makes Mind Flare that much more deadly against Puck.
* An ill-timed Phase Shift can turn into an easy setup for Impale.
Additional:
* Illusory Orb is easy to reflect with Spiked Carapace, either stunning Puck and setting up an easy Impale or forcing a premature Phase Shift.
* Puck is an intelligence hero that tends to build intelligence items, making it vulnerable to Mana Burn.
* An ill-timed Phase Shift can easily set Puck up to be stunned by Impale.
* Puck's low base armor and below average agility gain mean it is always susceptible to Vendetta.

* Spiked Carapace interrupts Starbreaker before Dawnbreaker has her Aghanim's Shard, as well as Solar Guardian during the initial channel, making her ineffective at joining and dealing damage in teamfights.
* The slow projectile and damage over time effect of Celestial Hammer makes it easy to stun Dawnbreaker if she attemps to engage or chase.
Additional:
* Spiked Carapace can stop Dawnbreaker's Solar Guardian which will eliminate her global presence and limits her movement around the map.

* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.

* Mind Flare does tons of damage against Lina because of her high intelligence.
* The mana burn from Vendetta also prevents Lina from casting her full combo.
* Spiked Carapace can easily be used to counter Lina's abilities because of their long cast animation, and could probably kill Lina outright if Laguna Blade is reflected.

* Heroes that can close the gap can easily chase her down, such as Timbersaw with Timber Chain and Anti-Mage with Blink.

* Spiked Carapace allows Nyx to get an easy long-duration stun on Weaver once he uses Shukuchi, and then he can follow up with Impale.
* Vendetta works as a great setup for both Impale and Spiked Carapace and can deal decent damage to Weaver. Additionally he can neutralize The Swarm beetles due to his invisibility duration.

* Nyx Assassin's Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* Mind Flare deals high damage due to Leshrac's high intelligence gain.
* Vendetta burns a large amount of Leshrac's essential mana pool.

* The huge physical damage taken from Vendetta will force Necrophos to use Ghost Shroud, which is good for a followup with Dagon and Ethereal Blade, both of which are common items on Nyx Assassin.
* Using Ghost Shroud also sets Necrophos up for a Mind Flare or Impale.

* Timber Chain can kite Troll Warlord extremely effectively.
* Whirling Death and Chakram deals lots of damage to Troll Warlord.
* Reactive Armor makes Timbersaw extremely resilient to Troll's attack damage and extreme attack speed, especially during Battle Trance.

* Timbersaw's innate durability is very hard to deal with as Naga Siren as she mostly relies on sustained damage rather than burst damage unless if she is played as Nuker. Timbersaw's high Pure Damage and low-cooldown AoE nukes can also destroy Naga Siren's illusions very fast. Timbersaw can also build Lotus Orb to reflect Ensnare back at Naga SIren.

* Reactive Armor prevents Broodmother's spiderlings from being able to effectively harass Timbersaw in the lane.
* Timber Chain's high mobility makes Silken Bola's slow irrelevant, unless Broodmother already bought her Orchid.
* Silken Bola's miss chance doesnt affect Rizzrack that much because he does not rely on his autoattacks much.
* Lotus Orb items for Timbersaw make Silken Bola useless.
* Timbersaw's abilities can destroy any trees that Broodmother attempts to hide in and his AoE abilities can quickly clear her Spiderlings.
Additional:
* Spiderlings deal almost no damage against Reactive Armor. They also die quickly from Timbersaw's AoE abilities.
* Broodmother has no mobility ability except the movement speed buff from Spin Web, allowing Timbersaw to easily escape her Silken Bola with Timber Chain.
* Timbersaw's tree-cutting abilities make it difficult for Broodmother to hide, especially near the edges of the map.

* All Timbersaw's abilities deal AoE pure damage and can easily deal with Phantom Lancer's illusions.
* Reactive Armor highly negates Phantom Lancer's physical damage, making him having a hard time killing Timbersaw.
Additional:
* Phantom Lancer's lack of burst damage and constant attacks will increase Reactive Armor to max level immediately.
* Coupled with Timber Chain, it makes an easy escape and almost impossible for Timbersaw to be killed by Phantom Lancer.
* Whirling Death and Chakram can instantly destroy large groups of illusions, negating Phantom Lancer's advantage, although Phantom Lancer usually builds Diffusal Blade. It can be a problem in late game.

* Timbersaw's pure damage will kill Dragon Knight surprisingly fast, especially if he gets caught in a bad position while laning.
* Items Lotus Orb for Timbersaw make Dragon Tail affected stunned back to Dragon Knight's although Timbersaw stricken by Dragon Tail.

* Vendetta is capable of removing most of Storm Spirit's large mana pool, along with dealing heavy damage and quickly depleting his chances of escaping a gank or fight.
Additional:
* Mana Burn removes much-needed mana for Ball Lightning.
* Spiked Carapace triggers on Static Remnant for an easy stun.

* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, Lion, Luna, Puck, Slark, Nyx Assassin, etc.

Additional:
* Enigma's uncontrollable damage from Malefice and Midnight Pulse make him easy to stun with Spiked Carapace.
* Black Hole can be easily interrupted by Impale or Spiked Carapace.

* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.

* Nyx Assassin's high burst damage, excellent ganking potential and multiple disables pose a threat to Muerta at all stages of the game.
* Mind Flare abuses Muerta's high intelligence to make short work of her low health.
* Spiked Carapace and Vendetta allow Nyx to escape or initiate well against Muerta's low mobility.
* As with most retaliation based abilities, Spiked Carapace can easily take advantage of Gunslinger's stray shots.

* Nyx Assassin can simply activate Spiked Carapace while under many Invoker's abilities to stun him.
* Nyx Assassin takes advantage of Invoker's massive intelligence gain to do tons of damage using Mind Flare, as the spell does more damage based on the target's intelligence.
* Vendetta burns a large amount of Invoker's essential mana pool.

* Silencer is rather squishy and has poor mobility without items, making him an easy target for Nyx.
* Silencer's intelligence steal ability is a complete disadvantage against Nyx Assassin as Mind Flare will deal increasing damage for each point of intelligence Silencer has stolen, turning Silencer's intelligence steal against him.
Additional:
* Last Word is extremely easy to reflect with Spiked Carapace for large amounts damage, due to triggering when Nyx Assassin casts a spell, but can still silence Nyx Assassin. It also has the added bonus of dealing more damage the more Intelligence Silencer has.
* Glaives of Wisdom quickly builds Silencer's Intelligence, making him a particularly prime target for Mana Burn.
* Silencer rarely builds survivability items, nor is he able to steal much Intelligence while surrounded by his team, and so is an excellent target for Vendetta.
* Silencer has no reliable way of dealing with a burrowed Nyx, and also lacks the ability to prevent Nyx from escaping with Vendetta,

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mind Flare will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.
Additional:
* Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel Life Drain, making him easy to hit with Impale.

* Outworld Destroyer's high intelligence makes him a good target for Mind Flare.
* If timed correctly, Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.
Additional:
* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed Sanity's Eclipse and/or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used Black King Bar beforehand.

* All of Timbersaw's spells deal AoE damage, killing Lycan's summons very quickly.
* Reactive Armor will gain stacks quickly because of Lycan's summons.

* Nyx Assassin can reflect Life Break with Spiked Carapace.

* Reactive Armor will quickly stack up from Familiar attacks, making Timbersaw hard to kill.
* Visage's low mobility makes it easy for Timbersaw to line up his abilities.