* Oracle's reliance on spamming his spells can be easily hindered by Silencer's Arcane Curse.
* Last Word and Global Silence negates Oracle's attempt to save his allies with his spells.
* Fate's Edict is useless against Glaives of Wisdom's pure damage.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Heroes with low mana pools (eg.Doom andTidehunter) will feel the effects of Silencer's Intelligence Steal far more than others.

* Guardian Angel can negate all the physical damage output during Chronosphere.
* When Faceless Void Time Walk's on top of an enemy it becomes a perfect target for Purification
Additional:
* Guardian Angel can negate all the physical damage output from Faceless Void during Chronosphere.
* If Faceless Void Time Walks on top of an ally Purification + Heavenly Grace can turn the fight around.

* Global Silence has faster-cast animation than Chronosphere, making Silencer can silence Faceless Void before he can cast Chronosphere.

* The pure damage provided by Purification is a great addition for killing Ember Spirit, as well as a good way of saving teammates.
* Guardian Angel will temporarily save his allies from Sleight of Fist's physical damage, and Ember Spirit is not a hero that will get Orchid Malevolence to counter it.

* Global Silence and Last Word can prevent Ember Spirit from casting Activate Fire Remnant to escape.
* Glaives of Wisdom also provide high pure damage that is not negated by Flame Guard.
* Arcane Curse is also a potent harassing tool in the laneing stage as its cooldown is lower than Flame Guard's.

* Guardian Angel makes allies immune to all physical damage, effectively causing Tidebringer to do no damage.
* Purification is a powerful, pure damaging heal that can save Omniknight's allies after Kunkka's large damage.

* Kunkka relies on his powerful AOE spells to turn the tides of teamfights. He cannot use them while silenced.
* Last Word can mess up Kunkka's ability synergy, silencing him in the middle of his strong combo.
* Global Silence can disable Kunkka's spell casting from anywhere on the map, even if Kunkka is spell immune at the time.

* Guardian Angel protects allies from Death Ward's physical damage.
* Purification and Heavenly Grace will most likely save teammates from dying to Maledict.

* Like any hero with a channeled spell, Last Word is a counter to it.
* Global Silence goes through spell immunity and prevents Witch Doctor from casting his spells.

* Heroes who possess abilities that can save targets from being killed by Reaper's Scythe: Abaddon, Bane, Outworld Destroyer, Shadow Demon, Omniknight, etc.

* Arcane Curse punishes Necrophos if tries to spam Death Pulse, increasing the duration of the slow and damage taken over time.
* Last Word heavily damages Necrophos and also silence him for a lenghty duration.
* Glaives of Wisdom will reduce temporarily Necrophos intelligence on each hit dealing hindering his ability to spam Death Pulse, also reducing his attack damage and mana pool; dealing increasing amounts of phisical and pure damage each time. Silencer will permanently steal Necrophos intelligence if Necrophos is killed by him or if he dies nears him.
* Global Silence turns Necrophos almost useless for a long time, allowing Silencer and his team to easily dispatch him, since Necrohpos heavily relies on his spells to survive.

* Heroes with spell immunity or pseudo-blinks which provide invulnerability: Lifestealer, Juggernaut, Omniknight, Huskar, and Tusk have spells which allow them to easily escape Dream Coil.

* Generally strong against lots of spellcaster-themed heroes, Puck fully relies on its skill set and cannot do almost anything when silenced.
* Arcane Curse disables Blink Dagger for quite some time, and is also effective against Puck as it tends to use its spells a lot.
* Glaives of Wisdom can do a lot of damage against Puck due to Puck's low agility gain and armor.
* Last Word can prevent Puck from getting a full combo off, limiting its effectiveness in team fights or ganks.
* Global Silence can take Puck out of fights entirely because of its long-duration silence.

* Omniknight can dispel Hex or Shackles with Heavenly Grace. He can also heal teammates who you disabled. The same goes for Abaddon's Aphotic Shield.

* With 4 active abilities, Shadow Shaman is weak against silencing foes such as Silencer, Drow Ranger and Death Prophet.

* Timbersaw is heavily reliant on his abilities for damage and escape, allowing Silencer to effectively disable him and make him useless in both team fights and 1v1 scenarios.
Additional:
* Arcane Curse deals repeated stacks of damage to Timbersaw because he relies on constantly using his abilities.
* Glaives of Wisdom deals pure damage and when cast manually, nearby creeps will not attack silencer, making it an effective harassment tool. The intelligence steal is also especially potent against Timbersaw since he often uses up all of his mana throughout the entire game.
* Although Last Word takes a while to trigger, it will break Timbersaw's ability combo and can be used to silence him.
* Global Silence will silence Timbersaw no matter where he is on the map. This can be used to help allies get a kill on him, or prevent Timbersaw from killing someone.

* Silencer's abilities hamper Windranger's effectiveness in battle, preventing her from comboing abilities and escaping using Windrun.
Additional:
* Glaives of Wisdom's intelligence steal can prove detrimental to Windranger, as she heavily relies on her abilities to be able to make an impact.
* Silencer's abilities hamper Windranger's effectiveness in battle, preventing her from comboing abilities and escaping using Windrun.

* Both Arcane Curse and Last Word punishes casters with spammable spells such as Sand King.
* As a strength caster, Intelligence Steal reduces Sand King's mana pool even more.
* Global Silence silences Sand King, effectively reducing Sand King's initiation and counter-initiation potential. It can also interrupt channeling of Epicenter.

* Purification heals a teammate targeted by Reality Rift and heavily damages Chaos Knight and his illusions in the process.
* Guardian Angel blocks all of Chaos Knight's damage for a long duration.
Additional:
* Phantasms can be easily killed with Purification.
* Heavenly Grace dispels the stun from Chaos Bolt and the armor reduction from Reality Rift.
* Guardian Angel works well against Chaos Knight's overwhelming reliance on physical burst damage.

* Glaives of Wisdom's intelligence steal will heavily punish Queen of Pain, as the loss of intelligence means that her mana pool is also reduced, since she is heavily reliant on her abilities to be able to make an impact.
* In the laning stage, Queen of Pain's reliance on spamming Shadow Strike and Scream of Pain will be significantly hindered by Arcane Curse.
* Last Word and Global Silence will render Queen of Pain defenseless unless she has an item/ally to dispel the silence.

* Crystal Maiden is squishy, is heavily spell reliant, has low base Intelligence, and is naturally slow, making her an ideal target for Silencer.
* Crystal Maiden's Freezing Field has a similar cooldown to Global Silence, therefore, Freezing Field can almost always be canceled to ruin aggressive Crystal Maiden initiations.

* Being a cast-oriented hero, Ezalor will suffer from all of Silencer's abilities.
* Global Silence is a guaranteed lengthy silence which will render Ezalor useless in a teamfight.
* Arcane Curse and Last Word are good against any caster, since they are extremely potent.
* However, it should be worth mentioning that a smart Ezalor will buy Eul's Scepter of Divinity to dispel Silencer's abilities. Combined with the level 20 talent (Chakra Magic applies a basic dispel), Ezalor can purge Silencer's abilities off allies and himself alike.

* Terrorblade is a double-edged sword type of matchup against Silencer. Although Terrorblade is more reliant on direct attacks to be effective, he relies on Sunder to save himself and stay alive and Last Word and Global Silence prevent him from doing that.
* Arcane Curse and Aghanim's Scepter upgraded Last Word help Silencer deal with Terrorblade's illusions from Conjure Image and Manta Style.
* With Last Word Mutes talent, Silencer can not only disable Terrorblade from turning tables with Sunder, but can also prevent him from using Manta Style and Black King Bar, items Terrorblade needs to be effective in teamfights.
* Glaives of Wisdom deals pure damage against the real Terrorblade, bypassing his high base armor.
* Global Silence can silence Terrorblade even if he has Black King Bar active, though bear in mind that Terrorblade can dispel Global Silence with Manta Style and Black King Bar if the Global Silence was activated first.
Additional:
* Silencer is a double-edged sword type of matchup against Terrorblade. Although Terrorblade is more reliant on direct attacks to be effective, he relies on Sunder to save himself and stay alive and Last Word and Global Silence prevent him from doing that.
* Arcane Curse, Glaives of Wisdom upgraded with 2 Glaives of Wisdom Bounces talent and Aghanim's Scepter upgraded Last Word help Silencer deal with Terrorblade's illusions from Conjure Image and Manta Style.
* With Last Word Mutes talent, Silencer can not only disable Terrorblade from turning tables with Sunder, but can also prevent him from using Manta Style and Black King Bar, items Terrorblade needs to be effective in teamfights.
* Glaives of Wisdom deals magical damage against the real Terrorblade, bypassing his high base armor. Later it can be upgraded with 2 Glaives of Wisdom Bounces talent to deal against Terrorblade's illusions. Alternatively, Silencer is a natural Revenant's Brooch wielder, which gives him another way to damaging Terrorblade through his high base armor.
* Global Silence can silence Terrorblade even if he has Black King Bar active, though bear in mind that Terrorblade can dispel Global Silence with Manta Style and Black King Bar if the Global Silence was activated first.

* Guardian Angel nullifies the physical damage from Exorcism during teamfights. And when upgraded with Aghanim's Scepter, it also prevents Death Prophet from pushing towers. However, Death Prophet can partially counter this issue with Eul's Scepter of Divinity, a common item on Death Prophet.
* Heavenly Grace dispels Silence.
Additional:
* Exorcism's damage is blocked by Guardian Angel.
* Heavenly Grace can dispel Silence allies if Omniknight is able to cast it.

* Arcane Curse stacks every time Bristleback uses an ability, forcing him to stop spamming his abilities, or take heavy health degeneration.
* Glaives of Wisdom steals intelligence both permanently and temporarily, causing mana issues for Bristleback.
* Last Word and Global Silence stops Bristleback from using his abilities altogether.
Additional:
* Bristleback will not be able to cast Viscous Nasal Goo or Quill Spray while silenced, effectively blocking a major part of the hero's damage and preventing Warpath charges from stacking.
* Arcane Curse slows Bristleback down and lasts longer the more abilities he uses. On the other hand, if he doesn't use any abilities, he will begin to lose Warpath charges.

* Last Word and Arcane Curse have the range to hit Dark Willow beyond Bramble Maze.
* Global Silence renders Dark Willow useless in teamfights.

* Guardian Angel negates most of Gyrocopter's physical АоЕ damage.
* Heavenly Grace dispels Homing Missile stun.

* Heavenly Grace reduces Fireblast stun time and dispels Ignite.
* Purification can heal damaged heroes if needed.

* Zeus' main source of damage is his low cooldown, high damage spells - meaning Last Word and Global Silence will pretty much take him out of the game for the duration.
* Zeus likes to spam his abilities, which makes him vulnerable to Arcane Curse.
* If Zeus dies near Silencer, he will begin to lose intelligence, reducing his mana pool, mana regen, and attack damage. Furthermore, if the game is long and Zeus dies often, the intelligence losses will also reduce his spell damage.
Additional:
* Silencer's Global Silence will render Zeus useless for 6 seconds in a team fight.
* Arcane Curse will punish Zeus for casting spells, which can cause continuous damage to him should he continue to cast spells.
* Last Word can silence Zeus and prevent him from spamming his spells.
* Silencer often builds Orchid Malevolence (or Bloodthorn) which can be used on spell casters like Zeus, forcing him to invest in a Linken's Sphere.

* Global Guardian Angel will protect his allies from Spectre's Haunt, both when they are alone and in teamfights.
* Purification is a major problem for melee enemies, Spectre included, since they must be next to an enemy in order to attack. The AoE damage also allows Spectre to be singled out from her illusions.
* Degen Aura will prevent Spectre from chasing Omniknight, further exacerbated by her terrible mobility outside Haunt.

* In the early game, Omniknight can look like an easy target for Spirit Breaker, but with Purification and Hammer of Purity, what could be an opportunity could quickly turn into disaster.
* Repel can be used to counter Charge of Darkness by minimizing the damage and lowering the stun duration with status resistance.
* Spirit Breaker's Greater Bash from all sources (Charge of Darkness or normal attacks) will deal no damage at all if Omniknight and his allies are protected with presence.
* Due to this, Spirit Breaker's damage will always be lower when targeting Omniknight.

* Pugna is very reliant on his abilities for damage which Silencer can take advantage off. But he has to be careful around the Nether Ward as Silencer's abilities cost a lot of mana to use.

* Because Warlock's abilities are all active abilities, Silencer can make his impact minimal.
* Arcane Curse prevents Warlock from using his abilities without increasing it's duration, which since all of Warlock's abilities are actives it is very effective against him.
* Last Word can prevent Warlock from casting his Fatal Bonds, Chaotic Offering, and Upheaval combo.
* Global Silence can nullify Warlock's impact in fights by preventing him from casting Fatal Bonds and Chaotic Offering, or by interrupting his Upheaval.

* Omniknight's healing prevents allies from dropping low enough for Culling Blade
* Heavenly Grace dispels Battle Hunger.
* Axe also tends to get close to allied heroes in order to damage them with his Counter Helix, which can easily be punished by Purification.

* Guardian Angel's near invulnerability denies Bloodseeker the bonuses from Thirst, preventing him from gaining the upper hand in teamfights.
* Purification's pure damage makes it hard for Bloodseeker to pursue enemies, and prevents him from replenishing his health by finishing off enemies.

* Silencer will most likely disrupt an initiation with his ultimate, Global Silence, prevent escape with his Last Word, and if Phoenix happens to die to him (or near him) enough times, he would sap enough of Phoenix's much needed Intelligence to make him a stronger foe and Phoenix with less mana than it already had.

* Silencer burns easily through her effective HP from Mana Shield, by taking away her intelligence.
* Arcane Curse punishes her repeatedly casting Mystic Snake to keep her mana pool high. He can force her to use Manta Style before he has cast Global Silence and Medusa usually does not want to build Black King Bar.

* Purification allows Omniknight to keep a hero trapped in the Static Storm alive.
* Repel is a reliable source of immunity to the effects of Static Storm.

* Heroes with silences : Bloodseeker, Riki, Silencer.

* Arcane Curse can effectively discourage Undying from casting his spammable abilities in a team fight, as Undying will have to suffer more damage and the slow due to the penalty duration of Arcane Curse.
* Last Word and Global Silence are able to silence Undying for up to 6 seconds, preventing Undying from gaining strength and healing his ally or himself.

* A well-timed Global Silence prevents Dazzle from saving allies with Shallow Grave or Shadow Wave. Items that could dispel the silence are expensive, and difficult for Dazzle to farm from a support role.
* Arcane Curse and Last Word cause long damage over time, which may outlast Shallow Grave.

* Silencer can stop Rearm, preventing Tinker from spamming his abilities/items or escaping.
* Tinker heavily relies on his mana pool and has mana issues throughout the entire game and Silencer's intelligence steal does not help with that.
Additional:
* As Tinker relies heavily on his spells to be effective, Last Word and Global Silence will render him largely useless.
* Arcane Curse effectively prevents Tinker from casting spells during its duration, as he will otherwise suffer heavy damage.
* Glaives of Wisdom deal pure damage, which make quick work of fragile heroes like Tinker.
* Silencer's intelligence steal permanently weakens Tinker since he's a hero who requires lots of mana to be effective.

* Purification does great damage to Clockwerk when fighting an enemy inside Power Cogs.
* Due to Clockwerk's very low damage output, Omniknight will have more than enough time to Purification and Heavenly Grace any enemy hero Clockwerk initiates on.
* For the same reasons, Omniknight also makes a powerful ally for Clockwerk when the situation is reversed.

* Guardian Angel completely negates all physical damage, including Omnislash.
Additional:
* Omnislash (and Swiftslash) is blocked by Guardian Angel.

* Guardian Angel completely counters Winter's Curse if Omniknight is able to cast it.
Additional:
* Guardian Angel completely counters Winter's Curse, allowing his team to survive Winter Wyvern's initiation.
* Purification and Repel are very useful against Arctic Burn, Splinter Blast and Winter's Curse as well.

* Heroes that can save their allies can be a big problem for Mars: Dazzle, Omniknight.

* Basically, Heroes that heavily rely on abilities for damage or escape, such as Queen of Pain and Storm Spirit.

Additional:
* Silencer's Intelligence Steal can reduce Storm Spirit's damage output if he gets some kills on laning phase.
* Last Word and Global Silence will make Storm Spirit an easy target.
* Global Silence can be used to prevent Storm Spirit from connecting abilities after a Ball Lightning on his targets.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Heroes who rely strongly on melee physical damage will fare badly against Omniknight's Guardian Angel: Phantom Assassin, Juggernaut, Dragon Knight, Lycan, Ursa, Troll Warlord

* Heroes with silence such as Riki, Silencer, or Night Stalker prevents Skywrath Mage from using his spells.

* Slark's dependence on Pounce and close range makes him very easy to hit with Purification and Hammer of Purity.
* Slark's damage, even with a high count of Essence Shift stacks, is easily negated by Omniknight's heals and Guardian Angel.

* Heroes with silencing abilities can be particularly deadly when Slark is trying to escape: Silencer, Death Prophet, Puck, Doom.

* Omniknight with Heavenly Grace
* Heroes that can remove the Track debuff with their skills:
* Abaddon with Aphotic Shield and Borrowed Time
* Huskar with Life Break
* Juggernaut with Blade Fury
* Legion Commander with Press the Attack
* Lifestealer with Rage and Infest
* Naga Siren with Mirror Image
* Omniknight with Heavenly Grace
* Oracle with Fortune's End and False Promise
* Phantom Lancer with Doppelganger
* Slark with Dark Pact
* Ursa with Enrage
* Weaver with Time Lapse
* Tidehunter with Kraken Shell when damage received reaches the threshold.

* Heroes with silences and hard stuns such as Doom, Silencer, and Lion can keep Mirana from Leaping away.

* Heroes with low mana pools (eg.Doom andTidehunter) will feel the effects of Silencer's Intelligence Steal far more than others.

* Silencer's Global Silence and Doom's Doom makes Earthshaker temporarily useless.

* Heroes with silencing abilities that are not blocked by Linken's Sphere, like Puck's Waning Rift, Death Prophet's Silence or Silencer's Global Silence.

* Heroes that have long silences, such as Night Stalker and Silencer, will prevent Abaddon from saving his allies effectively and disable the active component of Borrowed Time.

* Silencer can reduce Muerta's damage output with his Glaives of Wisdom, and since he commonly buys Revenant's Brooch, he will be able to attack her even through Pierce the Veil.
* Silencer has reliable, long-range silences in Last Word and Global Silence, preventing Muerta from using her spells as effectively.
* As Muerta tends to use her spells, particularly Dead Shot; Arcane Curse is very effective against her as that can punish her for doing so.

* Shadow Demon's main source of damage is his low cooldown, high damage spells - meaning Last Word and Global Silence will pretty much take him out of the game for the duration.
* Shadow Demon likes to spam his abilities, which makes him vulnerable to Arcane Curse.
* If Shadow Demon dies near Silencer, he will lose intelligence, reducing his mana pool, mana regen, and attack damage. Furthermore, if the game is long and Shadow Demon dies often, the intelligence losses will also reduce his spell damage.

* Riki takes a lot of damage from Purification while ganking Omniknight's allies or himself.
* Heavenly Grace instantly purges the slow from Diffusal Blade, while also providing a large amount of survivability for his victim.
* Degen Aura can hinder Riki's positioning tactics and put a heavy toll on Riki's already poor movement speed.
* Omniknight can easily save his allies by using Guardian Angel in combat.

* Repel can be used to dispel Gust on the allies affected by it.
* In team fights, Guardian Angel renders Drow Ranger's physical damage useless, and Drow Ranger has no way to purge it. And to make thing worse, Drow Ranger is not a common Nullifier wielder to counter this problem at all.

* Purification prevents Legion Commander from killing her target, and will always hit her during Duels.
* Guardian Angel completely wastes Duel's duration and can save an ally across the map when upgraded with Aghanim's Scepter.
Additional:
* Both Guardian Angel and Purification are perfect counters against Duel.

* Invoker is heavily dependent on his spells, making him useless during Global Silence, as well as interrupting Invoker during his combo.
* Arcane Curse is particularly deadly, because Invoker will continuously lose health if he keeps invoking and casting new spells.
* Last Word will silence Invoker when he casts Invoke, interrupting his combo.

* Arcane Curse makes it too difficult Lina from using her abilities, preventing her from building up Fiery Soul stacks without causing harm to herself.
* Last Word and Global Silence are great against Lina for the same reason, as well as interrupting her combos and preventing her from casting spells.

* Purification and Hammer of Purity can easily catch Phantom Assassin once she jumps with Phantom Strike in to attack.
* Heavenly Grace can be used to dispel slow from Stifling Dagger, and disables from the items Phantom Assassin relies on.
* Phantom Assassin depends entirely on physical attacks and her damage output is 100% physical. Therefore, since she has no any sources of magical damage output and hates going for items that deal magical damage like Dagon, Ethereal Blade and Revenant's Brooch, Guardian Angel will render her completely useless.
* Purification, Heavenly Grace and Guardian Angel can be used to save an allied hero before Phantom Assassin can finish them off with Coup De Grace.
Additional:
* Purification and Hammer of Purity can easily catch Phantom Assassin once she jumps with Phantom Strike in to attack.
* Heavenly Grace can be used to dispel slow from Stifling Dagger, and disables from the items Phantom Assassin relies on.
* Phantom Assassin depends entirely on physical attacks and her damage output is 100% physical. Therefore, since she has no any sources of magical damage output and hates going for items that deal magical damage like Dagon, Ethereal Blade and Revenant's Brooch, Guardian Angel will render her completely useless.
* Purification, Heavenly Grace and Guardian Angel can be used to save an allied hero before Phantom Assassin can finish them off with Coup De Grace.

* Purification can heal allies while dealing pure damage to Sven.
* Heavenly Grace can remove Storm Hammer's debuff immediately or make it a very mediocre stun.
* Guardian Angel negates Sven's massive damage during God's Strength.
* It should also be noted Sven can remove Omniknight's active spells with Aghanim's Scepter.

* Global Silence stops Snapfire's Mortimer Kisses.
* Last Word can prevent Snapfire from casting additional spells.

* Being mostly a physical damage dealer, Sniper's effectiveness is greatly reduced by Omniknight's Guardian Angel.
* Omniknight's Degen Aura allows him to slow sniper and catch him. Sniper has to then use some escape item.
* Omniknight can also protect an ally from being finished off by Assassinate by using Purification and Repel which grants a massive strength boost.

* Silences and other types of lockdown that prevent Weaver from using his spells: Silencer, Riki, Lion, Legion Commander, Shadow Shaman, Bane.

* Lion is extremely dependent on his abilities. Silences like Silencer's Last Word, magic resistance like Oracle's Fate's Edict, and dispels like Legion Commander's Press the Attack all make his abilities less effective.

* Lich is heavily reliant on his abilities to contribute to team fights, so be wary of enemies that can Silence: Bloodseeker, Death Prophet, Silencer, Drow Ranger, Skywrath Mage.

* Guardian Angel completely negates all of Lycan's damage since Lycan mainly deals physical damage.
* Purification can also be a problem for Lycan, as Purification deals damage around the target, which poses a problem for him and his summons.

* Arcane Curse can be cast from a long range to put Enigma's Blink Dagger on cooldown.
* Global Silence can interrupt Enigma's Black Hole channeling through Black King Bar and Linken's Sphere, making Silencer one of Enigma's hard counters. But bear in mind that Global Silence can be dispelled with Black King Bar if activated first.
Additional:
* Silencer can easily ruin Enigma's initiation, as Global Silence cancels Black Hole, even through Black King Bar and Linken's Sphere.

* Heroes with abilities or items that can silence or disable Anti-Mage for long periods of time will prevent him from Blinking away: Lion, Silencer, Shadow Shaman, Grimstroke, Witch Doctor, Riki, Faceless Void, Skywrath Mage, Puck.

* Heroes with strong dispels can dispel Bane's disables from their allies: Oracle, Legion Commander, Omniknight.

* Silencer's Intelligence Steal will heavily reduce Outworld Destroyer's damage output, particularly from Sanity's Eclipse.
* Last Word and Global Silence will take Outworld Destroyer out of the fight unless he has built Black King Bar.
Additional:
* Silencer's intelligence steal will heavily reduce Outworld Destroyer's damage output, especially if Destroyer dies a lot near Silencer and loses intelligence permanently.
* Global Silence and Last Word will render Outworld Destroyer helpless unless he has an item/ally to dispel silence.

* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: Invoker, Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.

* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, Silencer.