* Heroes with hiding abilities can protect disabled allies: Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter.

* Tanky melee heroes that can easily be kited, which allows Outworld Destroyer to deal heavy damage with Arcane Orb from a distance: Sven, Underlord, Bristleback.

Additional:
* Arcane Orb's pure damage can do great damage to Underlord.
* Sanity's Eclipse can tear down Underlord's health by a large amount, since his mana pool is very low compare to Outworld Destroyer's high mana pool.

* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.

* Heroes with a low attack speed or are fragile will find themselves unable to deal with Troll Warlord's high physical damage and attack speed, like Crystal Maiden or Sven.

* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.

* Lifestealer is a susceptible target to Fervor due to his non-mobile nature and lack of disables. Troll Warlord's ranged Berserker's Rage can also be used to kite Lifestealer safely. The root from its melee form also pierces magic immunity, which can potentially keep Lifestealer in place even while he is in Rage.
* Both Whirling Axes (melee) and Whirling Axes (ranged) can force Lifestealer to cast Rage too quickly and allow Troll Warlord to change strategies mid-fight, especially thanks to their separate cooldowns.
* Battle Trance allows Troll Warlord to survive Lifestealer's Feast and turn the fight in his favor.
Additional:
* The passive armor provided by Berserker's Rage makes Troll Warlord resilient to Feast in early game.
* The 60% miss chance given by Whirling Axes (Melee) is useful when Rage is not active.
* Battle Trance can purge Open Wounds, negating a large amount of Lifestealer's sustain in fights.

* Arcane Orb's pure damage, making Counterspell ineffective.
* Sanity's Eclipse will hit Anti-Mage while he is disabled from Astral Imprisonment, and forces him to take heavy damage due to his low intelligence.
* Essence Flux keeps Outworld Destroyer at high mana, thus greatly reducing the damage from Mana Void.
Additional:
* Counterspell doesn't work versus Arcane Orb because it does pure damage.
* Anti-Mage cannot burn all of Outworld Destroyer's mana without disables due to Essence Flux.
* Anti-Mage's Manta Style illusions are quickly destroyed by Arcane Orb.
* However, if the enemy has multiple means of removing mana, Mana Void becomes a threat to Outworld Destroyer, Anti-Mage has better mobility than Outworld Destroyer with Blink, and Counterspell blocks a large portion of the damage from Sanity's Eclipse.

* Troll Warlord's passive root, high attack speed, and blind from Whirling Axes makes him an exceedingly difficult opponent for Anti-Mage to take down in a one-on-one fight.
* Troll Warlord's low mana causes him to take little damage from Mana Void.
Additional:
* Whirling Axes (Melee) provides a 60% miss chance, preventing Anti-Mage from burning Troll Warlord's small mana pool.
* Troll Warlord's passive root allows him to very effectively fight an Anti-Mage by preventing Anti-Mage from Blinking away. This is even more effective when combined with a Skull Basher or Abyssal Blade.
* Counterspell will do nothing to prevent Troll Warlord's high physical damage.
* Due to Troll Warlord's abysmal base intelligence and intelligence gain, he is one of the worst targets to use Mana Void on.

* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.

* Heroes that rely on right-clicks will find that their attacks will miss a lot, due to Whirling Axes (Melee)'s miss chance. Such heroes include Phantom Assassin, Terrorblade, and Morphling.

* Most Illusion based heroes (like Chaos Knight and Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.

Additional:
* Arcane Orb deals pure damage against the real Terrorblade, which allows it to bypass his high base armor.
* Arcane Orb and Sanity's Eclipse will make very short work of Terrorblade and his illusions.
* Aghanim's Shard upgraded Astral Imprisonment can be used to save an ally on which Terrorblade has used Sunder.

* Terrorblade cannot go one on one against Troll Warlord as Troll Warlord will overwhelm him faster than the other way around thanks to Whirling Axes (Melee) that will cause his attacks to miss, and Fervor that can give Troll Warlord huge amounts of attack speed to outmatch Terrorblade, even during Metamorphosis.
* Troll Warlord's high attack speed from Fervor combined with Skull Basher and Abyssal Blade means that Terrorblade will have almost no chance to use Sunder to save himself.
* Even if Terroblade manages to use Sunder on Troll Warlord, Troll Warlord will simply be able to nullify it's effect with Battle Trance.
* Overall, any attempt for Terrorblade to engage and kill Troll Warlord will hurt him more than the other way around.
Additional:
* Terrorblade cannot go one on one against Troll Warlord as Troll Warlord will overwhelm him faster than the other way around thanks to Whirling Axes (Melee) that will cause his attacks to miss, and Fervor that can give Troll Warlord huge amounts of attack speed to outmatch Terrorblade, even during Metamorphosis.
* Troll Warlord's high attack speed from Fervor combined with Skull Basher and Abyssal Blade means that Terrorblade will have almost no chance to use Sunder to save himself.
* Even if Terroblade manages to use Sunder on Troll Warlord, Troll Warlord will simply be able to nullify it's effect with Battle Trance.

* Outworld Destroyer has a huge damage from Arcane Orb, which is why in a 1 on 1 skirmish Storm Spirit simply cannot defeat him in damage. Since Outworld Destroyer will stop gank Storm Spirit with his Astral Imprisonment, and then kill him if he decides to fight
Additional:
* Outworld Destroyer has a huge damage from Arcane Orb, which is why in a 1 on 1 skirmish Storm Spirit simply cannot defeat him in damage. Since Outworld Destroyer will stop gank Storm Spirit with his Astral Imprisonment, and then kill him if he decides to fight

* Mobility heroes will often be rooted by Troll Warlord and unable to escape, like Storm Spirit.

* Primal Beast is mostly played in the offlane role, so picking a carry who can escape from him is essential. Heroes such as Troll Warlord, Lone Druid and Outworld Destroyer, or generally any carry with a stun, slow or ability to fight back will stop him from having the good start he needs.

* The ensnare from melee Berserker's Rage can prevent Primal Beast from dealing further Trample damage and can allow Troll Warlord to relentlessly build Fervor on him.
* Whirling Axes (Ranged) can slow down Primal Beast while trampling and allow Troll Warlord to better control him from range.
* Whirling Axes (Melee) can blind Primal Beast if he attempts to auto-attack Troll Warlord after a fully charged Uproar.
* Battle Trance will make Primal Beast a sitting duck should he be rooted and attacked to death.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Whirling Axes (Melee) makes it hard for Phantom Assassin to land a Coup De Grace.
* Troll Warlord often buys Silver Edge and Monkey King Bar, the items that greatly help against Phantom Assassin's Blur ability.
* Battle Trance completely negates Phantom Assassin's large damage output, preventing Troll Warlord from dying easily. The lifesteal also allows Troll Warlord to restore much of his health.
Additional:
* Troll Warlord can build a Silver Edge or a Monkey King Bar to completely ignore Blur.
* Whirling Axes (Melee) provides a 60% miss chance, making a Coup de Grace critical strike very hard to land.
* Battle Trance negates Coup de Grace, preventing Troll Warlord from dying to her critical hits.

* Astral Imprisonment prevents Legion Commander from killing her opponents in Duels.
Additional:
* Outworld Destroyer can save an ally hero caught by Duel with Astral Imprisonment, and he can inflict heavy damage on Legion Commander with Arcane Orb to aid his ally. However, if he gets caught, he is unlikely to survive the duel, due to his lack of durability.

* Troll Warlord's melee bash and high attack speed can often help him and his allies win Duels against Legion Commander.

* Tanky melee heroes that can easily be kited, which allows Outworld Destroyer to deal heavy damage with Arcane Orb from a distance: Sven, Underlord, Bristleback.

* Whirling Axes (Melee)'s blind makes Sven nearly useless in the early game and allows Troll Warlord to take him on comfortably.
* Battle Trance will mean Sven will never take Troll out in a 1vs1 with equal farm.
Additional:
* Berserker's Rage together with Troll Warlord's high attack speed gives Troll a high chance of rooting enemies, which allows Troll Warlord to man-fight Sven.
* Whirling Axes (Melee) provides a 60% miss chance, and the passive armor provided by Berserker's Rage makes Troll resilient to physical damage in early game. Sven's God's Strength is much less effective as a result.
* Beware that Sven can farm much faster than Troll Warlord by stacking ancients and clearing them with Great Cleave.

* Astral Imprisonment allows Outworld Destroyer to save himself or his teamates during Omnislash.
* Juggernaut's low mana from his low intelligence gain means that he'll take a lot of damage from Sanity's Eclipse.

* Troll Warlord's ability to attack as a ranged hero allows him to destroy Juggernaut's Healing Ward from afar.
* Battle Trance, when activated during Omnislash, allows Troll Warlord to survive the full duration of Omnislash and retaliate once it is over.

* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, Silencer.

Additional:
* Outworld Destroyer can dodge Life Break with Astral Imprisonment, leaving him unharmed while Huskar loses HP.
* Sanity's Eclipse can deal massive damage to Huskar before he builds up his Berserker's Blood stacks due to Huskar's low mana pool.

* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.

Additional:
* Whirling Axes (Melee) provides a 60% miss chance, resulting in Huskar's attacks missing a lot of the time if it isn't dispelled.
* Troll Warlord's Fervor ramps up in a very similar way as Huskar's Berserker's Blood: as soon as Huskar has high enough health regeneration, Troll Warlord has a high enough attack speed to negate it.

* Arcane Orb and Sanity's Eclipse can often kill Chen or his allies before he can save them with Hand of God.
* Arcane Orb, Astral Imprisonment and Sanity's Eclipse can clear waves of Chen's converted creeps.

* Battle Trance and Fervor can help Troll Warlord deal with Enchantress through Untouchable.
Additional:
* Untouchable's attack speed slow is easily remedied by Fervor stacks and Battle Trance.
* Troll Warlord is a natural Silver Edge carrier, disabling Enchantress' Untouchable.

* Astral Imprisonment protects an ally for much of Rolling Thunder's duration, especially at the lower levels. As Rolling Thunder has a considerable cast animation, an Outworld Destroyer with Blink Dagger can initiate on him and destroy his timing.

* Arcane Orb allows Outworld Destroyer's attacks to deal pure damage that can bypass Naga Siren's armor, and which can clear her illusions in no time.
* Astral Imprisonment can be used to harass Naga Siren by reducing her maximum mana and to prevent Naga Siren from escaping with Song of the Siren. Outworld Destroyer can also use Astral Imprisonment to protect himself from Naga Siren.
* Sanity's Eclipse will most likely instantly kill Naga Siren along with her illusions. Even if Naga Siren survives Sanity's Eclipse, it's mana allergy debuff will discourage Naga Siren from using her abilities as the mana allergy will heal Outworld Destroyer if she uses them for it's duration.

* Outworld Destroyer's high burst damage is not negated by Bristleback's passive. So, even if Bristleback turns his back on Outworld, he can decimate Bristleback quickly.
* If Bristleback attempts to flee, or tries to close the gap, Outworld can banish him with Astral Imprisonment, both reducing Bristlebacks much needed mana and allowing Outworld to move in front of him, forcing him to take the full damage from his spells. This will also allow Outworld to land a devasting Sanity's Eclipse, without it being reduced by Bristleback's passive.

* Astral Imprisonment is a versatile nuisance:
* If it is cast on a low-enough-health unit at least 1 second into Shallow Grave's duration, the Shallow Grave will end during the imprisonment, and the target will take lethal damage when released.
* It can be used remove Dazzle from the fight at a time he could have saved someone.
* It lets himself or an ally dodge all of Poison Touch's effects, for long enough to recover their Blink Dagger.

* Generally speaking, Spectre is a strong teamfighter but a weak manfighter. She has no tool to deal with troll warlord once he has his sight locked on her.
* Troll often buys Silver Edge and Monkey King Bar, which greatly countered Spectre's passive and item build (Silver Edge can disable passive while providing some damage, Monkey King Bar provides accuracy to counter Radiance and Butterfly miss chance).
* Black King Bar allows troll to bypass the damage return from Blade mail should Spectre attempts to fight back Troll. However, Black King Bar is generally not very effective against Spectre as her skills can pierce the spell immunity. Still, it offers protection against Blade mail, a common item for Spectre in the mid game.
* Troll has high lifesteal from Battle Trance and Satanic, which help him survive the damage from Desolate should the break duration is over.
* Battle Trance and Fervor mean Spectre will have a hard time fighting troll and cannot take him down, even with equal farm.

* Outworld Destroyer is not exceptionally dangerous to Necrohpos because of his Ghost Shroud, but his Astral Imprisonment can save his allies from Necrophos's Reaper's Scythe, though only if he uses it at the right time, If an Outworld Destroyer is nearby, Necrophos should not use Reaper's Scythe unless he has banished himself, or has banished two heroes within 15 seconds

* Sanity's Eclipse deals more damage the less max mana the heroes hit by it have, making Pudge an ideal target.
* Outworld Destroyer can save allies or himself caught by Dismember or Meat Hook with Astral Imprisonment.

* Outworld Destroyer can disrupt Slark's attacks with Astral Imprisonment either by banishing Slark or his target.
* Slark's low heathpool means he will die quickly to Arcane Orb if he is directly attacked by Outworld Destroyer
* Slark has low intelligence gain, making him easy to finish with Sanity's Eclipse if he tries to run with Shadow Dance
Additional:
* Arcane Orb deals pure damage, which ignores the armor granted from permanent agility stacks.
* Astral Imprisonment can disrupt any Pounce attempt by banishing the leashed ally.
* Slark's low mana pool makes him more susceptible to Sanity's Eclipse.

* Kraken Shell's dispel does not restore mana lost through Astral Imprisonment, and the stolen mana can really hurt Tidehunter's ability to initiate
* Arcane Orb high pure damage ignores Tidehunter's Armor, and is barely affected by his Kraken Shell's damage block
* It is also completely unaffected by Anchor Smash, due to it relying on Outworlds Mana pool
* Sanity's Eclipse is effective on Tidehunter's poor mana pool, While it is reduced by Kraken Shell, the damage reduction is negligible.

* Astral Imprisonment can be used to protect allies by imprisoning either them or Spirit Breaker.
* Arcane Orb will heavily drain Spirit Breaker's maximum mana, rendering him almost useless and unable to cast spells. And considering how Spirit Breaker's intelligence is very low, Sanity's Eclipse will deal a lot of damage to him.
* Even if Spirit Breaker survives Sanity's Eclipse, mana allergy applied by the Sanity's Eclipse will discourage Spirit Breaker from using his abilities as it will cause him to lose health and heal Outworld Destroyer.

* Outworld Destroyer can steal more mana with Astral Imprisonment from Skywrath Mage with Shield of the Scion (granted by Aghanim's Shard). Shield of the Scion grants Skywrath Mage bonus intelligence every time he deals magic damage to an enemy hero with his abilities. The higher his intelligence, the larger his mana pool. Since Astral Imprisonment steals based on the target's max mana, Outworld Destroyer can steal much more mana from Skywrath Mage.

* Astral Imprisonment can allow Outworld Destroyer to save himself or allies from Kunkka's full kit.
* Sanity's Eclipse deal a large amount of damage, as Kunkka's mana pool is much smaller than Outworld Destroyer's.
* Arcane Orb deals pure damage, shredding through Kunkka and his team even with Ghostship's buff.

* Outworld Destroyer's pure and magical damage is particularly effective against Earthshaker.
* Astral Imprisonment catches Earthshaker while he blinks in, preventing him from executing his combo.
* Earthshaker has mana troubles, and Outworld Destroyer's abilities can press this by stealing intelligence comes from Arcane Orb, therefore depleting his mana pool and mana regeneration.
* Sanity's Eclipse deals high damage to Earthshaker, due to his low intelligence and mana pool.

* Astral Imprisonment can save allies from a Black Hole combo. When upgraded with Aghanim's Scepter and Aghanim's Shard, it becomes exceedingly difficult for Enigma to land a good Black Hole against Outworld Destroyer and his team.
* Astral Imprisonment can also cancel Black Hole while Enigma does not have Black King Bar.
* Arcane Orb and Sanity's Eclipse can often make a short work out of Enigma and his Eidolons.

* Due to Fervor and Battle Trance, Troll Warlord has a significant attack speed, enabling him to crush Tombstone quickly.
* Undying usually stays at the front line with no disables, making him an easy target for Troll Warlord.

* Berserker's Rage will repeatedly trap Bloodseeker in a one-on-one fight.
* Whirling Axes (Melee) blinds Bloodseeker, causing him to miss 60% of the time, and therefore reduces his ability to gain the upper hand in teamfights.

* Sanity's Eclipse does massive damage to Wraith King who naturally has a low mana pool and typically doesn't build items to increase it.
* Wraithfire Blast's slow projectile speed makes it easy to avoid using Astral Imprisonment.

* The pure damage provided by Arcane Orb is a great addition for killing Ember Spirit.
* Astral Imprisonment fully negates all magic damage of Flame Guard and Searing Chains and will temporarily save himself from Sleight of Fist's physical damage, and Ember Spirit is not a hero that can counter these skills.

* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.

* Astral Imprisonment wastes Borrowed Time's duration.
* Outworld Destroyer's Sanity's Eclipse can kill Abaddon before Borrowed Time triggers due to the lack of intelligence for Abaddon.

* Heroes that can protect or dispel stunned allies such as Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.

* Any hero who can survive Magnus's initiations and manfight him: Huskar, Faceless Void, Weaver, Abaddon, Troll Warlord, Alchemist, Dragon Knight, Night Stalker, Viper.

* Any hero that can nullify effects of Chronosphere: (Keeper of the Light with Aghanim's Scepter during daytime, Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, Shadow Demon, Earth Spirit with Aghanim's Scepter) or protecting him in other ways (Dazzle, Oracle, Abaddon) can greatly limit Chronosphere's potential.

* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, Clockwerk, Drow Ranger, Abaddon, Faceless Void, Weaver, Outworld Destroyer.

* Any hero with high attack speed will be a threat to Phoenix when it initiates, as they can easily tear down a Supernova, perhaps even while debuffed by Fire Spirits: Juggernaut, Clinkz, Troll Warlord, Beastmaster, Lina.

Additional:
* Due to Fervor and Battle Trance, Troll Warlord is one of the best heroes to deal with Supernova.

* Troll Warlord can root and deal a lot of damage to a single Meepo while lifestealing through the assault from the other Meepos. Meepo needs expensive items like Ethereal Blade or Heaven's Halberd to be able to fight him.

* Ursa struggles against heroes with strong (and especially undispellable) disables (Disruptor, Puck, Shadow Demon, Outworld Destroyer and etc).

* Arcane Orb's pure damage ignores Mars' Bulwark.
* Astral Imprisonment can be used to stop Mars from being disruptive or save allies from his abilities.
* Sanity's Eclipse deals high damage to Mars, due to his low intelligence pool.

* Astral Imprisonment allows Outworld Destroyer to save himself or ally from Invoker's combo, or remove Invoker from a fight temporarily.
* Arcane Orb's pure damage will deal a lot of damage against Invoker's mediocre strength gain.
* E.M.P. is useless against Outworld Destroyer by activating Equilibrium.
* However, be aware that Sanity's Eclipse will most likely not deal any damage at all, due to Invoker's high intelligence gain compared to Outworld Destroyer's.

* Arcane Orb's constant pure damage output is devastating to Dragon Knight.
* Dragon Knight's relatively low mana pool leads to heavy damage from Sanity's Eclipse, which also bypasses his armor.

* Astral Imprisonment can be used to protect allies from Jakiro's various abilities, It can also be cast on Jakiro to break his combos (Macropyre into Ice path into Dual Breath), while at the same time, stealing his much needed mana.
* Aghanim's Shard upgraded Astral Imprisonment allows Outworld Destroyer and his allies to move while imprisoned, which allows them to leave the area of Jakiro's abilities.
* As Outworld Destroyer is prone to buying Meteor Hammer, he can combine it with Astral Imprisonment and Arcane Orb's high pure damage that can quickly decimate Jakiro, And unlike most heroes, Outworld doesn't particularly care who he targets.
* Outworld is also a common Black King's Bar carrier, and Jakiro's only tool to counter it is the Aghanim's Scepter upgraded Macropyre

* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.

* Whirling Axes (Melee) provides a 60% miss chance, which can make the attack speed bonus from Hunter in the Night largely ineffective.
* Berserker's Rage together with Battle Trance and Fervor stacks gives him a high chance of rooting Night Stalker, which allows Troll Warlord to man-fight Night Stalker in any stage of the game, regardless of whether or not it's night.
* Night Stalker is not a common Monkey King Bar carrier to counteract this problem.

* Arcane Orb's pure damage penetrates Guardian Angel's defense.
* Astral Imprisonment's mana steal is devastating to Omniknight's already low mana pool.

* Astral Imprisonment allows Outworld Destroyer to waste over half of Pierce the Veil, or protect an ally from Dead Shot's fear while also reducing Muerta's maximum mana.
* Sanity's Eclipse will deal massive damage to Muerta if her maximum mana gets too low. And even if she survives it, Sanity's Eclipse's Mana Allergy debuff will discourage her from using abilities as that will result in healing Outworld Destroyer.

* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.

* Most Illusion based heroes (like Chaos Knight and Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.

* Arcane Orb's pure damage ignores Timbersaw's Reactive Armor.
* Astral Imprisonment, if timed correctly, can interrupt Timber Chain, preventing him from escaping.
Additional:
* Arcane Orb deals constant pure damage, which bypasses Timbersaw's Reactive Armor.
* Sanity's Eclipse can hit targets inside Astral Imprisonment, which helps Outworld Destroyer finish off Timbersaw before he escapes with Timber Chain. It can also drain his mana, limiting his ability to escape should he survive.

* Outworld Destroyer doesn't care if Razor steals his damage because he does most of his damage through Arcane Orb.
* Astral Imprisonment can prevent Razor from using the stolen damage from Static Link or chasing with Eye of the Storm.
* Sanity's Eclipse will do a ton of damage to Razor due to his low mana pool.

* Outworld Destroyer's pure damage from Arcane Orb can go through Cold Embrace.
* Outworld Destroyer can negate the healing from Cold Embrace using Astral Imprisonment, and steal mana while doing so.
* Outworld Destroyer's damage during Winter's Curse is reduced due to Arcane Orb being unable to target allies.
Additional:
* Winter Wyvern must never put her allies in Cold Embrace against Outworld Destroyer as Arcane Orb will continue to deal damage to the defenseless hero.
* Arcane Orb does not hit his allies when he is taunted by Winter's Curse, making it weak against allies, but strong versus enemies.
* Astral Imprisonment can protect a target inflicted with Winter's Curse.

* Outworld Destroyer's pure and magical damage is particularly effective against Axe.
* Astral Imprisonment is an excellent way to defend against an initiating Axe.
* Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Destroyer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.