Phantom Assassin
* 
Hoof Stomp and 
Double Edge can often burst down Phantom Assassin from early to mid game.
* 
Retaliate makes it very unlikely for Phantom Assassin to win the lane against Warrunner. Double Edge can also be used to wear her down, as she has a much smaller health pool than that of Centaur Warrunner until purchasing a 
Ring of Health. 
Stifling Dagger will also trigger Retaliate and 
Blur cannot evade Retaliate.
* Centaur Warrunner's tankiness in combination with armour items that Axe often purchases like 
Blade Mail, 
Crimson Guard, 
Assault Cuirass and 
Shiva's Guard can make Phantom Assassin's attacks only tickle Centaur Warrunner.
* Centaur Warrunner just has to be careful about 
Fan of Knives from 
Aghanim's Shard and 
Coup De Grace, as Fan of Knives can disable Retaliate even if Centaur Warrunner is spell immune.
Additional:
* Hoof Stomp and Double Edge can often burst down Phantom Assassin from early to mid game.
* Retaliate makes it very unlikely for Phantom Assassin to win the lane against Warrunner. Double Edge can also be used to wear her down, as she has a much smaller health pool than that of Centaur Warrunner until purchasing a Ring of Health. Stifling Dagger will also trigger Retaliate and Blur cannot evade Retaliate.
* Centaur Warrunner's tankiness in combination with armour items that Centaur Warrunner often purchases like Blade Mail, Crimson Guard, Assault Cuirass and Shiva's Guard can make Phantom Assassin's attacks only tickle Centaur Warrunner.
* Centaur Warrunner just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can disable Retaliate even if Centaur Warrunner is spell immune.
Nyx Assassin
* Centaur's low Intelligence makes 
Mind Flare do low damage.
* With some creative skill builds, Centaur's Hoof Stomp stun duration should always last longer than 
Spiked Carapace stun, so escaping unscathed is hard for Nyx.
* With 
Blink Dagger and detection, Centaur can devastate Nyx in the open.
* However, bear in mind that Nyx can also easily initiate on Centaur Warrunner as well if he uses Spiked Carapace in anticipation, and with 
Vendetta. The damage from Retaliate will be reflected back to Centaur Warrunner, stunning him with no chance to react after he's revealed himself, and should guarantee a successful 
Impale.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: 
Broodmother, 
Phantom Lancer, 
Chaos Knight, 
Lycan, 
Naga Siren, 
Shadow Shaman, 
Visage, 
Nature's Prophet, 
Terrorblade, 
Warlock, 
Wraith King.
Nyx Assassin
* Even though Visage's Familiars from 
Summon Familiars are fragile and can be killed quickly with Nyx Assassin's high burst damage, they can deal many instances of damage quickly, minimizing the effectiveness of Spiked Carapace.
* 
Gravekeeper's Cloak and tanky item builds make Visage hard for Nyx to kill with his burst damage. Aghanim's Shard upgraded Gravekeeper's Cloak also allows Visage to use 
Stone Form to both recover himself and stun Nyx Assassin if he is close enough to Visage.
* Visage's long range on 
Soul Assumption and 
Grave Chill make him hard to escape from, and Soul Assumption's low cooldown outmatches Spiked Carapace.
Phantom Assassin
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without 
Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* 
Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.
* 
Aghanim's Scepter gives Broodmother access to 
Spinner's Snare, which allows her to create invisible lines on her webs from 
Spin Web that will root Phantom Assassin, deal damage over time to Phantom Assassin and reveal Phantom Assassin if she unwittingly steps on them, disrupting her attempts to initiate or escape with with 
Phantom Strike while also alerting Broodmother on her attempts to ambush her and her allies.
Additional:
* Phantom Assassin's single target abilities make her very helpless against swarms of Spiderlings without Battle Fury.
* Because Phantom Assassin is always reliant on critical strikes, Broodmother will usually have enough time to use Spin Web to save herself.
* Silken Bola can cripple Phantom Assassin greatly due to her being 100% reliant on physical attacks.
* Aghanim's Scepter gives Broodmother access to Spinner's Snare, which allows her to create invisible lines on her webs from Spin Web that will root Phantom Assassin, deal damage over time to Phantom Assassin and reveal Phantom Assassin if she unwittingly steps on them, disrupting her attempts to initiate or escape with with Phantom Strike while also alerting Broodmother on her attempts to ambush her and her allies.
Nyx Assassin
* With Aghanim's Scepter, Broodmother will gain access to Spinner's Snare, which will allow her to create invisible lines on her webs from Spin Web that will root, deal damage over time, and reveal enemy heroes if they unwittingly step on them. This allows Broodmother to keep her allies alerted on heroes who rely on invisibility-themed and movement-themed abilities and items to surprise enemy heroes and disrupt ganking attempts of enemy heroes: 
Phantom Assassin, 
Nyx Assassin, 
Mirana, 
Bounty Hunter, 
Templar Assassin, 
Riki, 
Spirit Breaker, 
Anti-Mage, 
Tusk, 
Ursa, Nature's Prophet, 
Enigma, 
Void Spirit, 
Magnus etc.
Phantom Assassin
* In general, Brewmaster's Cinder Brew and Thunder Clap makes him good against physical damage carries: Ursa, 
Clinkz, 
Faceless Void, 
Troll Warlord, Templar Assassin, Phantom Assassin.
Nyx Assassin
* 
Cyclone from Storm in 
Primal Split can waste Nyx's Spiked Carapace, since its duration is shorter than the Cyclone's.
Phantom Assassin
* Phantom Assassin relies on her Blur to stay alive, but is very vulnerable to Sand King's heavy magic damage.
* With Burrowstrike, Sand King can often catch Phantom Assassin before she can use her 
Black King Bar.
* Sand King can dodge Stifling Dagger with Sandstorm.
* Phantom Assassin has a hard time killing Sand King because of his high mobility.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: 
Jakiro, 
Viper, 
Venomancer, 
Huskar, 
Ember Spirit, 
Dark Seer, 
Sand King, 
Doom, 
Dawnbreaker. However, this also means they are easily stunned.
Phantom Assassin
* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: 
Axe, Viper, 
Meepo, Jakiro, 
Pugna, 
Slark, Venomancer etc.
Nyx Assassin
* 
Corrosive Skin minimizes the damage from Impale and Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from 
Poison Attack, 
Nethertoxin, Corrosive Skin and 
Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common 
Silver Edge wielder to counter this problem at all.
Additional:
* Corrosive Skin minimizes the damage from Impale and Mind Flare, and anything else Nyx Assassin tries to throw at Viper.
* Nyx Assassin cannot survive several poison damage-over-time output from Poison Attack, Nethertoxin, Corrosive Skin and Viper Strike, not even while he has Spiked Carapace active. And to make things worse, Nyx Assassin is not a common Silver Edge wielder to counter this problem at all.
Phantom Assassin
* 
Whirling Axes (Melee) makes it hard for Phantom Assassin to land a Coup De Grace.
* Troll Warlord often buys Silver Edge and 
Monkey King Bar, the items that greatly help against Phantom Assassin's Blur ability.
* 
Battle Trance completely negates Phantom Assassin's large damage output, preventing Troll Warlord from dying easily. The lifesteal also allows Troll Warlord to restore much of his health.
Additional:
* Troll Warlord can build a Silver Edge or a Monkey King Bar to completely ignore Blur.
* Whirling Axes (Melee) provides a 60% miss chance, making a Coup de Grace critical strike very hard to land.
* Battle Trance negates Coup de Grace, preventing Troll Warlord from dying to her critical hits.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, 
Legion Commander, 
Lina, 
Luna, Lycan, 
Slardar, Slark, Troll Warlord, 
Witch Doctor.
Phantom Assassin
* Heroes that rely on physical damage are ineffective against Dragon Knight due to his high armor: Phantom Assassin,
Bloodseeker, 
Lifestealer, Troll Warlord, 
Sven
Nyx Assassin
* Dragon Knight's heavy armor negates Vendetta's burst physical damage. His large HP pool also gives him a good chance of surviving Nyx Assassin's follow-up nuke damage.
Phantom Assassin
* Slark's 
Pounce allows him to close the gap on Phantom Assassin and prevent her from escaping with Phantom Strike.
* As a hero who typically builds Silver Edge, Slark can use it to disable Phantom Assassin's Blur and Coup de Grace, thus taking down her attack evasion and drastically reducing her damage output.
* Because Phantom Assassin is always reliant on critical strikes, Slark will have plenty of time to escape with Pounce, 
Shadow Dance and Silver Edge (provided that he purchased it already).
* 
Depth Shroud from Aghanim's Shard will allow Slark to save both, himself and his allies from Phantom Assassin with Shadow Dance, and to freely fightback against her without removing invisibility upon attacking.
* 
Essence Shift is much more harmful for Phantom Assassin than for other heroes, as losing the agility means that her physical damage will be also reduced, which can also weaken Coup de Grace if Slark manages to steal lots of agility from her.
* Overall, any attempt for Phantom Assassin to take down Slark will hurt her more than Slark.
Additional:
* Slark's Pounce allows him to close the gap on Phantom Assassin and prevent her from escaping with Phantom Strike.
* As a hero who typically builds Silver Edge, Slark can use it to disable Phantom Assassin's Blur and Coup de Grace, thus taking down her attack evasion and drastically reducing her damage output.
* Because Phantom Assassin is always reliant on critical strikes, Slark will have plenty of time to escape with Pounce, Shadow Dance and Silver Edge (provided that he purchased it already).
* Depth Shroud from Aghanim's Shard will allow Slark to save both, himself and his allies from Phantom Assassin with Shadow Dance, and to freely fightback against her without removing invisibility upon attacking.
* Essence Shift is much more harmful for Phantom Assassin than for other heroes, as losing the agility means that her physical damage will be also reduced, which can also weaken Coup de Grace if Slark manages to steal lots of agility from her.
* Overall, any attempt for Phantom Assassin to take down Slark will hurt her more than Slark.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Phantom Assassin
* 
Doom with the {ValueColor:1|Doom applies Break|25tal} {Symbol:Talent} talent can be useful against heroes with troublesome passive skills while also disabling them for a long time: Phantom Assassin, 
Enchantress, Huskar, 
Underlord.
Nyx Assassin
* A well-timed Doom prevents Nyx Assassin escaping with Vendetta and fighting back with Spiked Carapace.
* Doom's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off.
Phantom Assassin
* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned Phantom Strike will make Phantom Assassin an easy target for counter-attack with 
Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even better if Luna buys Aghanim's Scepter.
* 
Moon Glaives can ignore Blur's evasion if Luna attacks an enemy near Phantom Assassin.
* Luna can counter Blur's evasion by buying either Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can disable Moon Glaives and 
Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be solved by buying 
Ethereal Blade, which is a situational item on Luna.
Additional:
* Even though Phantom Assassin can easily kill Luna in few strikes, Luna can also do the same to Phantom Assassin if she is not careful.
* An ill-timed and ill-positioned Phantom Strike will make Phantom Assassin an easy target for counter-attack with Eclipse if she does not have Black King Bar available to use and if Phantom Assassin cannot kill Luna fast enough. This can be even worse if Luna buys Aghanim's Scepter.
* Moon Glaives can ignore Blur's evasion if Luna attacks an enemy near Phantom Assassin. Aghanim's Shard upgraded Moon Glaives can also reduce damage from Coup De Grace and Moon Glaives Phantom Assassin inflicts on Luna and damage Spirit Phantom Assassin she is close to her. And the Aghanim's Shard upgraded Moon Glaives have true strike for their duration, which renders Blur's evasion insignificant.
* Luna can counter Blur's evasion by buying either Silver Edge, or Monkey King Bar, which are common items on Luna.
* Luna just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can deal health-based damage to Luna and disable Moon Glaives and Lunar Blessing while Coup De Grace can deal serious damage to her even if she is spell immune, though this issue can be partially solved by buying Ethereal Blade, which is a situational item on Luna.
Nyx Assassin
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* 
Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy 
Eye of Skadi and 
Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy 
Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Additional:
* Even though Nyx Assassin can easily kill Luna with his high burst damage, Luna can also do the same to him if he is not careful.
* Lucent Beam can deal a fair amount of damage to Nyx Assassin if he has no Spiked Carapace available to use. Although Luna should be patient using Lucent Beam on Nyx Assassin when he uses Spiked Carapace.
* As Luna commonly buys Black King Bar, she can use it to freely attack Nyx Assassin whenever he tries to defend himself with Spiked Carapace during teamfights. Luna can also buy Eye of Skadi and Manta Style to survive Nyx Assassin's burst damage and distract him.
* Though Vendetta can deal serious damage to Luna and avoid Eclipse, smart Luna will always buy Dust of Appearance to provide vision on Nyx Assassin to her and her team.
Phantom Assassin
* All assassin-type carries in a one against one situation: Meepo, Phantom Assassin, Riki, Ursa. Luna's only chances are that she buys Ethereal Blade or Black King Bar to gain a slight edge against them, or both items if necessary.
Phantom Assassin
* Heroes with gap-closing abilities who attempt to use them for escaping Bloodseeker will suffer serious damage from Rupture: Phantom Assassin, Anti-Mage, Faceless Void, Riki, Slark, Spirit Breaker.
Nyx Assassin
* Heroes with invisibility will be detected by Thirst when they have low enough health: Bounty Hunter, Templar Assassin, Riki, Clinkz, 
Weaver, 
Treant Protector, Nyx Assassin.
Additional:
* While Burrowing, Nyx is an easy target for a 
Blood Rite, and his only way to counter it is a well-timed Spiked Carapace.
* 
Thirst is always a threat to Nyx Assassin, hindering his attempt of escape using Vendetta and rendering him unable to surprise Bloodseeker's allies.
* 
Rupture also prevents Nyx Assassin from escaping with Vendetta, as it forces him to stay still.
Phantom Assassin
* With 
Normal Punch from Aghanim's Scepter, Dark Seer can gain an advantage against heroes who rely on evasion as Normal Punch has true strike: Phantom Assassin, 
Windranger, 
Hoodwink.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Phantom Assassin
* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Phantom Assassin
* 
Ensnare prevents using any kind of movement abiilties, Making Naga Siren good against heroes who rely on gap-closing abilities to escape: Phantom Assassin, Magnus, Slark, Riki, Faceless Void, 
Storm Spirit.
Nyx Assassin
* Nyx Assassin's skillset is mostly single-targeted, therefore he will have difficulties against heroes with illusions and summons: Naga Siren, Broodmother, Lycan, Visage, Phantom Lancer. And to make things worse, Nyx Asassin is not a common Battle Fury, 
Maelstrom, 
Mjollnir, 
Gleipnir or 
Radiance wielder to counter this problem.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Nyx Assassin
* Nyx Assassin's skillset is mostly single-targeted, therefore he will have difficulties against heroes with illusions and summons: Naga Siren, Broodmother, Lycan, Visage, Phantom Lancer. And to make things worse, Nyx Asassin is not a common Battle Fury, Maelstrom, Mjollnir, Gleipnir or Radiance wielder to counter this problem.
Phantom Assassin
* With Aghanim's Scepter upgraded 
Infest, Lifestealer can use it on enemy heroes to attack them and disarm them from inside, even if they are spell immune, which can give him the edge over the heroes he's weak against like Ursa, Phantom Assassin, Terrorblade or Troll Warlord.
Nyx Assassin
* 
Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if Vendetta is on cooldown. Nyx Assassin cannot counter Rage with Spiked Carapace because Rage gives Lifestealer spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
* 
Open Wounds from Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with Dust of Appearance or a 
Gem of True Sight. Aghanim's Scepter upgraded Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. and Nyx Assassin cannot counter this with Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
* Overall, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.
Additional:
* Like with Juggernaut's 
Blade Fury, Rage allows Lifestealer to freely attack Nyx Assassin and hunt him down if Vendetta is on cooldown. Nyx Assassin cannot counter Rage with Spiked Carapace because Rage gives Lifestealer spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Lifestealer while he is spell immune.
* Open Wounds from Aghanim's Shard allows Lifestealer to severely slow down Nyx Assassin while also allowing his team to recover themselves while attacking Nyx Assassin. Open Wounds can also fester and spread if Nyx Assassin takes enough damage that will trigger the spread while he is affected with Open Wounds.
* Infest combined with an ancient creep makes Nyx Assassin an easy target to surprise with Dust of Appearance or a Gem of True Sight. And similarly to Juggernaut's 
Omnislash and 
Swiftslash from Aghanim's Scepter, Aghanim's Scepter upgraded Infest can also allow Lifestealer to infest, disarm and freely attack Nyx Assassin from within. And Nyx Assassin cannot counter this with Spiked Carapace because Lifestealer is invulnerable while attacking the infested enemy hero from within.
* Like with Juggernaut, any attempt for Nyx Assassin to gank and kill Lifestealer will hurt Nyx Assassin more than Lifestealer.
Phantom Assassin
* Lifestealer, at even farm levels, will often fall against other man-fighting non-Strength cores like Ursa, Phantom Assassin or Troll Warlord as he cannot truly rely on sustain from 
Feast.
Additional:
* Rage does absolutely nothing against Phantom Strike with items.
* Feast and 
Ghoul Frenzy are very difficult to utilise thanks to Blur.
* Lifestealer generally wants to buy items that make him hard to kill, not an Monkey King Bar which only offers damage.
Nyx Assassin
* Nyx Assassin wants to start ganking as soon as he gets his Vendetta. Keeping him Tracked prevents him from ganking, and thus from doing his job in the game.
* Nyx Assassin has a lot of armor and health regen, making the nuke damage from Shuriken Toss very good against him.
Additional:
* 
Track hinders Nyx Assassin's ganking and escaping attempts with Vendetta, making him an easy kill for gold as well.
* Bounty Hunter can also use Track on Nyx Assassin while he has Spiked Carapace active without getting stunned as Track deals no damage at all before using 
Shuriken Toss.
Nyx Assassin
* Duel's long duration prevents Nyx Assassin escaping from Vendetta. With Aghanim's Scepter, she can also bypass Spiked Carapace.
Nyx Assassin
* Blade Fury makes Juggernaut immune to all Nyx's abilities, except Vendetta.
* Omnislash. and Swiftslash can burst Nyx down, ignoring Spiked Carapace. However, Vendetta can be used to escape, canceling Omnislash/Swiftslash.
Additional:
* Juggernaut's entire skillset greatly counters Nyx Assassin's Spiked Carapace, his most important ability.
* Blade Fury allows Juggernaut to freely attack Nyx Assassin, and deal heavy damage to Nyx Assassin. Nyx Assassin cannot counter Blade Fury with Spiked Carapace because Blade Fury gives Juggernaut spell immunity. And besides Vendetta, Nyx Assassin has no other way of dealing damage to Juggernaut while he is spell immune.
* 
Healing Ward allows Juggernaut to recover himself and his allies from Nyx Assassin's damage output.
* Omnislash and Swiftslash from Aghanim's Scepter can quickly finish off Nyx Assassin. And just like Blade Fury, Nyx Assassin cannot counter neither Omnislash and Swiftslash from Aghanim's Scepter with Spiked Carapace because both abilities render Juggernaut invulnerable. And if Nyx Assassin has no Vendetta available to use for escaping, both abilities will kill him very quickly before he can do anything.
* Overall, any attempt for Nyx Assassin to gank and kill Juggernaut will hurt Nyx Assassin more than Juggernaut.
Phantom Assassin
* 
Enfeeble greatly reduces Phantom Assassin's attack damage, and if her attack damage is weak, Coup De Grace will also suffer from attack damage reduction as well. Enfeeble also reduces cast range of Phantom Assassin's abilities, making her unable to harass with Stifling Dagger and to use Phantom Strike at longer distances.
* 
Nightmare and 
Fiend's Grip can ground Phantom Assassin, who normally blinks around with Phantom Strike, and stop her from outputting damage.
* Phantom Assassin's low health pool early on makes her susceptible to {A|Brain Sap|Bane
Additional:
* Enfeeble greatly reduces Phantom Assassin's attack damage, and if her attack damage is weak, Coup De Grace will also suffer from attack damage reduction as well. Enfeeble also reduces any healing Phantom Assassin receives, making her unable to heal herself with Phantom Strike, and it also reduces cast range of Phantom Assassin's abilities, making her unable to harass with Stifling Dagger and to use Phantom Strike at longer distances.
* Nightmare and Fiend's Grip can ground Phantom Assassin, who normally blinks around with Phantom Strike, and stop her from outputting damage, even with Black King Bar.
* Phantom Assassin's low health pool early on makes her susceptible to Brain Sap and Fiend's Grip's heavy nuke damage.
Phantom Assassin
* 
Dispersion makes it hard for Phantom Assassin to burst down Spectre while also reflecting back Phantom Assassin's high burst damage against herself.
* Black King Bar is useless for Phantom Assassin against Spectre as all of her skills pierce spell immunity.
* Spectre only needs to be careful against Fan Of Knives from Aghanim's Shard, as it can disable 
Desolate and Dispersion, though this issue can be solved by buying Blade Mail, which is a common item on Spectre.
Additional:
* Dispersion makes it hard for Phantom Assassin to burst down Spectre while also reflecting back Phantom Assassin's high burst damage against herself.
* Black King Bar is useless against Spectre as all of her skills pierce spell immunity.
Phantom Assassin
* 
Firestorm can deal serious damage to Phantom Assassin during laning.
* 
Pit of Malice prevents Phantom Assassin from either escaping or engaging with Phantom Strike.
* Phantom Assassin's damage output is entirely physical, therefore 
Atrophy Aura is very hazardous for her in most of the stages, particularly since it also affects Coup De Grace, hindering Phantom Assassin's main source of damage.
* Without proper items and any area-of-effect ability/item, Phantom Assassin cannot stop Underlord and his team to escape with 
Fiend's Gate, and she has nothing to intercept Underlord and his team when they use Fiend's Gate to teleport on any area of the map outside of Fan of Knives from Aghanim's Shard.
Additional:
* Firestorm can be used to deal serious damage to Phantom Assassin during laning that ignores evasion from Blur.
* Pit of Malice prevents Phantom Assassin from either escaping or engaging with Phantom Strike.
* Phantom Assassin's damage output is entirely physical, therefore Atrophy Aura is very hazardous for her in most of the stages, particularly since it also affects Coup De Grace, hindering Phantom Assassin's main source of damage.
* Without proper items and any area-of-effect ability/item, Phantom Assassin cannot stop Underlord and his team to escape with Fiend's Gate, nor she can intercept them if Underlord chooses to teleport on any area of the map.
Nyx Assassin
* Heroes who are entirely reliant on dealing physical damage and/or have very little to no area-of-effect abilities will make Underlord tickle and will have no effect against him thanks to his Atrophy Aura, and will also be unable to ambush Underlord and his team if Underlord chooses to use Fiend's Gate to get to a designated point of the map: Phantom Assassin, Terrorblade, Troll Warlord, 
Drow Ranger, Phantom Lancer, Chaos Knight, Sven, Wraith King, Bounty Hunter, 
Alchemist, Templar Assassin, Nyx Assassin, 
Bane.
Nyx Assassin
* Heroes with magical or pure damage output will not have any problems against Atrophy Aura at all: Luna, Lina, Jakiro, Pugna, Bane, 
Snapfire, 
Muerta, Nyx Assassin, Enigma, 
Tinker, Witch Doctor, 
Zeus, 
Crystal Maiden.
Phantom Assassin
* Overgrowth prevents Phantom Assassin from using 
Blink Strike even through her spell immunity.
* Living Armor reduces Phantom Assassin's physical damage whenever she attempts to gank an allied hero.
Phantom Assassin
* Despite her high mobility, 
Hex or 
Earth Spike can lock Phantom Assassin down, make her vulnerable and mitigate her damage output.
* Lion relies entirely on his abilities to be effective, rendering Phatnom Assassin's high evasion through ineffective against him. And Phantom Assassin's low health pool makes her vulnerable to Lion's magical burst without Black King Bar.
Nyx Assassin
* 
Corrosive Haze hinders Nyx Assassin's ganking attempts with Vendetta, as well as reducing his armor and make him very vulnerable due to his low health pool.
* 
Guardian Sprint allows Slardar to catch up with Nyx Asssassin and finish him off if he has vision over him.
Phantom Assassin
* 
Static Link can lower the damage output from Coup de Grace procs, hindering Phantom Assassin's main source of damage. And Phantom Assassin is not a common 
Linken's Sphere wielder to counter this problem.
* 
Eye of the Storm strikes cannot be evaded by Blur.
* Both Static Link and Eye of the Storm pierces spell immunity, as Phantom Assassin is often reliant on Black King Bar.
Additional:
* Static Link can lower the damage output from Coup de Grace procs, hindering Phantom Assassin's main source of damage.
* Eye of the Storm strikes cannot be evaded by Blur.
* Both Static Link and Eye of the Storm pierces spell immunity, as Phantom Assassin is often reliant on Black King Bar.
Phantom Assassin
* Morphling's naturally high armor thanks to his high agility makes it hard for Phantom Assassin to take him down with Coup de Grace.
Phantom Assassin
* Phantom Assassin's high physical damage is greatly reduced by Bulwark.
* God's Rebuke has true strike, ignoring the evasion from Blur.
Phantom Assassin
* 
Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger.
* Phantom Assassin has a moderate health pool and usually appears in the front line of battle, making her vulnerable to Timbersaw's pure burst damage output.
* Timbersaw can easily escape from Phantom Assassin thanks to his 
Timber Chain.
Additional:
* Reactive Armor helps Timbersaw sustain harassment from Stifling Dagger, as well as ganking attempts.
* Phantom Assassin is a hero with moderate HP pool, and usually appears in the front line of battle. Because Blur does nothing against spells, she is vulnerable to Timbersaw's skills.
* Timbersaw can easily escape from Phantom Assassin thanks to his Timber Chain.
Phantom Assassin
* Fate's Edict cripples many heroes who rely on attacks, such as Phantom Assassin, Sven, or Enchantress, without a dispel or a Black King Bar.
Nyx Assassin
* Heroes that have a weak laning stage: 
Spectre, Nyx Assassin, 
Clockwerk, Spirit Breaker, 
Omniknight, 
Pudge.
Phantom Assassin
* Heroes who just want to farm and avoid Lone Druid early will find it very hard to do so when he starts knocking on towers: Templar Assassin, Phantom Assassin, Ember Spirit, 
Morphling.
Phantom Assassin
* Many physical-only single-target heroes like Lifestealer, Sven, Wraith King, Phantom Assassin, Templar Assassin can have their damage mitigated by Cold Embrace.
Phantom Assassin
* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: 
Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots
Phantom Assassin
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, 
Vengeful Spirit, Doom, Bane, 
Beastmaster, Pudge, 
Medusa, Warlock.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Nyx Assassin
* Enigma is fragile, and lacks escapes, being dependent on Blink Dagger for mobility. Ganking Heroes or Heroes with burst damage will likely kill him before he can do anything. Such Heroes include: Lina, 
Lion, Luna, 
Puck, Slark, Nyx Assassin, etc.
Additional:
* Enigma's uncontrollable damage from 
Malefice and 
Midnight Pulse make him easy to stun with Spiked Carapace.
* 
Black Hole can be easily interrupted by Impale or Spiked Carapace.
Phantom Assassin
* Heroes with single-target abilities will be overwhelmed by Lycan and his summons: Wraith King, Bane, Phantom Assassin.
Nyx Assassin
* Lycan's high health allows him to easily shrug off Nyx Assassin's burst damage and fend him off.
* As Lycan commonly buys Black King Bar, he can use it to freely attack Nyx Assassin and chase after him with 
Shapeshift.
* Lycan can also use his wolves from 
Summon Wolves to attack Nyx Assassin while he has Spiked Carapace active without getting stunned himself.
Phantom Assassin
* Phantom Assassin's Blur is a real problem for Lycan, as he relies entirely on direct attacks to deal damage.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Phantom Assassin
* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: 
Queen of Pain, Phantom Assassin
Phantom Assassin
* Hex abilities prevent attacking, ability and item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and 
Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility: Doom, 
Disruptor with Aghanim's Scepter, 
Dazzle with Aghanim's Shard
Phantom Assassin
* In early to mid stage, Silence is also a great way to counter escape oriented heroes such as Anti-Mage, Queen of Pain, and Phantom Assassin to prevent them from escaping, provided that they don't have any basic dispels.
Phantom Assassin
* Jakiro's reliance on his abilities can cause struggles for heroes who rely on evasion or blinds to get upper hand: Phantom Assassin, Windranger, Riki, Troll Warlord, 
Keeper of the Light.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Phantom Assassin
* Heroes with good mobility to avoid Jakiro's abilities and with good chase to punish Jakiro from pushing a tower: Bloodseeker, Ember Spirit, 
Juggernaut, Phantom Assassin, Weaver.
Phantom Assassin
* Heroes with heavy early and mid-game magical damage are also problematic for Phantom Assassin due to being able to easily kill her before she can gain an item advantage over them: Lina, 
Necrophos, Nyx Assassin, 
Gyrocopter, Jakiro, 
Death Prophet.
Phantom Assassin
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa, Warlock.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Phantom Assassin
* Heroes who can delivers a big chunk of damage in few hits will find themselves struggle against Templar Assassin's Refraction: Sven, Phantom Assassin, Ursa, Wraith King, Lifestealer
Nyx Assassin
* Heroes who rely on invisibility, such as Bounty Hunter, Clinkz, Mirana, Nyx Assassin and Riki, as they will be revealed if caught by Chronosphere.
Phantom Assassin
* Heroes who cannot prevent Sven from killing towers will often struggle from a small map very early, such as Phantom Assassin, Storm Spirit and Phantom Lancer.
Nyx Assassin
* Some abilities deals damage from an independent source and not from the hero itself, so Nyx cannot counter them with Spiked Carapace: illusions or summoning units, 
Homing Missile, 
Nimbus, 
Mass Serpent Ward, 
Death Ward and especially 
Techies's mines.
Nyx Assassin
* Impale and Spiked Carapace stun can be instantly dispelled by Aphotic Shield.
* Abaddon can use Borrowed Time and easily heal for the duration of Borrowed Time by Nyx's burst damage.
Nyx Assassin
* Nyx Assassin might not kill Abaddon with his nuke, but a support Abaddon will struggle to protect an ally from him.
Phantom Assassin
* 
Purification and 
Hammer of Purity can easily catch Phantom Assassin once she jumps with Phantom Strike in to attack.
* 
Heavenly Grace can be used to dispel slow from Stifling Dagger, and disables from the items Phantom Assassin relies on.
* Phantom Assassin depends entirely on physical attacks and her damage output is 100% physical. Therefore, since she has no any sources of magical damage output and hates going for items that deal magical damage like 
Dagon, Ethereal Blade and 
Revenant's Brooch, 
Guardian Angel will render her completely useless.
* Purification, Heavenly Grace and Guardian Angel can be used to save an allied hero before Phantom Assassin can finish them off with Coup De Grace.
Additional:
* Purification and Hammer of Purity can easily catch Phantom Assassin once she jumps with Phantom Strike in to attack.
* Heavenly Grace can be used to dispel slow from Stifling Dagger, and disables from the items Phantom Assassin relies on.
* Phantom Assassin depends entirely on physical attacks and her damage output is 100% physical. Therefore, since she has no any sources of magical damage output and hates going for items that deal magical damage like Dagon, Ethereal Blade and Revenant's Brooch, Guardian Angel will render her completely useless.
* Purification, Heavenly Grace and Guardian Angel can be used to save an allied hero before Phantom Assassin can finish them off with Coup De Grace.
Nyx Assassin
* Heroes who can drain mana can make Omniknight useless after he uses one or two abilities: Lion, Anti-Mage, Nyx Assassin.
Phantom Assassin
* Phantom Assassin is known to be weak against bursts of magical damage, something Primal Beast excels at from the beginning of the game. He can use this to his advantage by constantly hunting Phantom Assassin down, especially if she is left alone to farm.
* Primal Beast is a good carrier of Ethereal Blade, 
Vanguard and Shiva's Guard all of which are very good against Coup de Grace and Phantom Strike.
* Even though Primal Beast does a lot of physical damage early on, later once Blur becomes more potent, she may find herself being overwhelmed by Trample and Onslaught instead.
* Primal Beast's ultimate goes through spell immunity and his level 25 talent makes it even more devistating against Phantom Assassin.
* Primal Beast can dispel Stifling Dagger and any attack modifers it applies with his left level 15 talent.
Nyx Assassin
* Like above, supports with reliable stuns can be a massive problem and force Black King Bar in fights unideally, such as Shadow Shaman, Lion, Nyx Assassin.
Phantom Assassin
* Heroes capable of perofrming interceptions who can anticipate and counter-initiate after Phantom Assassin blinks on them with Phantom Strike will often kill her than the other way around: Axe, Bane, Dawnbreaker, 
Centaur Warrunner, Luna, Medusa, Omniknight, Pudge, 
Razor, Terrorblade, Underlord.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Nyx Assassin
* Spiked Carapace can stop Dawnbreaker's Solar Guardian which will eliminate her global presence and limits her movement around the map.
Additional:
* Spiked Carapace interrupts 
Starbreaker before Dawnbreaker has her Aghanim's Shard, as well as 
Solar Guardian during the initial channel, making her ineffective at joining and dealing damage in teamfights.
* The slow projectile and damage over time effect of 
Celestial Hammer makes it easy to stun Dawnbreaker if she attemps to engage or chase.
Phantom Assassin
* Sniper's lack of mobility and reliance on attack range makes him an easy target for Phantom Assassin to jump on.
Additional:
* Stifling Dagger and Phantom Strike allow Phantom Assassin to close the gap with Sniper and prevent his escape.
* Blur allows Phantom Assassin to approach Sniper while invisible and dodge much of Sniper's damage. It can also disjoint Assassinate.
* Coup De Grace quickly cuts through Sniper's low health; one or two procs will usually kill him.
* Fan of Knives from Aghanim's Shard can deal damage to Sniper's maximum health and disable 
Headshot and 
Take Aim.
Nyx Assassin
* 
Assassinate is easy to reflect with Spiked Carapace for massive damage.
* 
Shrapnel's area damage can set up an easy stun with Spiked Carapace, especially when combined with Vendetta.
* In the early game, Sniper's low health pool and high intelligence makes him easy prey for Nyx Assassin.
Phantom Assassin
* Phantom Assassin doesn't care about Silencer's spells as she relies on right-clicks more than spells.
* Phantom Assassin often builds Black King Bar, which allows her to remove Global Silence before engaging.
Nyx Assassin
* 
Last Word is extremely easy to reflect with Spiked Carapace for large amounts damage, due to triggering when Nyx Assassin casts a spell, but can still silence Nyx Assassin. It also has the added bonus of dealing more damage the more Intelligence Silencer has.
* 
Glaives of Wisdom quickly builds Silencer's Intelligence, making him a particularly prime target for Mana Burn.
* Silencer rarely builds survivability items, nor is he able to steal much Intelligence while surrounded by his team, and so is an excellent target for Vendetta.
* Silencer has no reliable way of dealing with a burrowed Nyx, and also lacks the ability to prevent Nyx from escaping with Vendetta,
Additional:
* Silencer is rather squishy and has poor mobility without items, making him an easy target for Nyx.
* Silencer's intelligence steal ability is a complete disadvantage against Nyx Assassin as Mind Flare will deal increasing damage for each point of intelligence Silencer has stolen, turning Silencer's intelligence steal against him.
Phantom Assassin
* Heroes with high burst damage and Black King Bar can take down Dark Willow quickly: Phantom Assassin, Sven, Wraith King
Nyx Assassin
* Nyx Assassin's high burst damage can be the bane of Dark Willow, as her low health makes it difficult to survive long enough to escape through Shadow Realm.
* Spiked Carapace can be triggered by walking deliberately into Bramble Maze, leaving Dark Willow stunned and defenseless.
Phantom Assassin
* Phantom Strike allows Phantom Assassin jump directly to Io.
* Coup de Grace can make a short work of Io's low health and armor.
Nyx Assassin
* Heroes with either magical, physical or pure damage burst: Bane, Ember Spirit, 
Leshrac, Lina, Luna, Nyx Assassin, Phantom Assassin, 
Skywrath Mage, Tinker, Ursa, Void Spirit.
Phantom Assassin
* Generally, heroes that can close the gap on Drow Ranger to cancel her Marksmanship such as Phantom Assassin, Spirit Breaker, and Tusk are effective at limiting her power and bursting her down.
Nyx Assassin
* Nyx Assassin has a lot of burst damage from his Impale, Mind Flare, Dagon, and the bonus damage from Vendetta. All of this damage is enough to kill Drow Ranger.
* Nyx Assassin is usually invisible most of the time thanks to his ability Vendetta, which allows him to gank Drow Ranger easily.
* However, 
Gust is extremely dangerous for Nyx Assassin, as it's silence can render Nyx Assassin unable to lock down Drow Ranger. And if Gust hits Nyx Assassin while he is invisible with Vendetta, Drow Ranger will be able to detect him and foil his ganking attempts on her because Gust reveals invisible units.
Phantom Assassin
* Heroes that can easily bypass Chen's creeps to get to Chen: Riki, Tusk, Clinkz, 
Sniper, Slark, Phantom Assassin, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, Spirit Breaker.
Nyx Assassin
* Heroes with either magical, physical or pure damage burst can often kill Chen or his allies before he can use Hand of God: Lina, Luna, Techies, 
Shadow Fiend, Pugna, Nyx Assassin.
Phantom Assassin
* Ancient Apparition has no escape or reliable control and is very fragile, which makes him an easy target for anyone who can get on top of him, like Phantom Assassin or Clinkz.
Nyx Assassin
* Heroes with silence and mana drain abilites, as Ancient Apparition relies entirely on his abilities: 
Invoker, 
Silencer, Nyx Assassin, Skywrath Mage, Shadow Shaman, Lion and etc.
Nyx Assassin
* Vendetta can deal great damage against her. However, it requires an direct attack, so Nyx Assassin may have difficulties applying Vendetta on her.
* Enchantress's lack of mobility makes her a primary target for ganking with Vendetta.
* Mind Flare can deal a great damage against her due to being an Intelligence hero.
* Spiked Carapace can reflect Impetus and stun Enchantress.
Additional:
* Spiked Carapace reflects the damage from 
Impetus.
* Enchantress is a rather squishy hero, making her fall easily to Nyx Assassin's high burst damage.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Phantom Assassin
* Nature's Prophet's low mobility and health pool allow Phantom Assassin to destroy him in the early game.
* Phantom Strike allows Phantom Assassin to jump in and out of 
Sprout, provided she has vision.
Nyx Assassin
* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin.
Phantom Assassin
* Blur makes it hard for Monkey King to stack Jingu Mastery.
* Phantom Strike allows Phantom Assassin to blink directly to Monkey King during Wukong's Command, bypassing all his clones.
* Coup de Grace's high damage can kill Monkey King quickly, thus ending Wukong's Command prematurely.
Nyx Assassin
* Spiked Carapace stops Snapfire's 
Mortimer Kisses.
Phantom Assassin
* 
Fade Bolt is not enough to burst Phantom Assassin down without the help of other stolen spells.
* 
Rubick has little armor and can be Phantom Assassin's primary target.
* 
Telekinesis is the only way for Rubick to retaliate if being jumped on, but the lockdown duration is generally not enough for Rubick to escape.
* Few of Phantom Assassin's spells grants utility for Rubick.
* Phantom Assassin's spells strengthes her assault power combined with her physical damage output, yet Rubick is not considered a physical damage dealer.
* With that said, Blur could be of use for Rubick to hide on back in teamfights waiting for the key spell without fearing of being initiated.
Nyx Assassin
* Spiked Carapace allows Nyx to get an easy long-duration stun on Weaver once he uses Shukuchi, and then he can follow up with Impale.
* Vendetta works as a great setup for both Impale and Spiked Carapace and can deal decent damage to Weaver. Additionally he can neutralize The Swarm beetles due to his invisibility duration.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Phantom Assassin
* Assuming they have not bought anti-evasion items, attack-dependent heroes such as Ursa, Terrorblade or Lifestealer can be a minor threat for Phantom Assassin early in the game, and may even be completely dominated by her thanks to her evasion.
Nyx Assassin
* Nyx Assassin deals large amounts of pure damage with Vendetta and magical damage with Impale and Mind Flare, allowing him to ignore Terrorblade's armor and burst his low health pool down before he can use 
Sunder.
* Nyx Assassin commonly buys 
Urn of Shadows, Dagon and 
Meteor Hammer which deal magic damage that ignore Terrorblade's armor.
* However, Terrorblade is a natural Eye of Skadi and Black King Bar wielder, and once he gets those items, Nyx Assassin's solo kill potential against Terrorblade will be gone.
Nyx Assassin
* A good Nyx can reflect Queen of Pain's Sonic Wave with his Spiked Carapace, or even initiate a gank on her in Vendetta while she farms a creep wave with Scream of Pain.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a Dagon, provided he can get his full combo off.
Phantom Assassin
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa, Warlock.
Additional:
* If Phantom Assassin jumps on Pudge first with Phantom Strike, she will be a very easy target for Pudge's 
Meat Hook and 
Dismember combo.
* Even though it can deal damage based on Pudge's max health, Fan of Knives from Aghanim's Shard cannot disable Pudge's 
Flesh Heap as Flesh Heap is one of the few passive abilities that cannot be disabled by break.
* Both Meat Hook and Dismember ignore spell immunity which allows Pudge to disable Phantom Assassin even while she has Black King Bar active.
* Pudge occassionally buys armor items like Blade Mail, which in combination with many stacks from Flesh Heap can make Phantom Assassin have little effect against Pudge.
Phantom Assassin
* Generally heroes who don't rely on magical damage, such as Sven, Phantom Assassin, and 
Outworld Destroyer, as they can practically ignore Flesh Heap's damage block.
Nyx Assassin
* Impale and Spiked Carapace can be used to cancel Dismember easily, and can even do so when Pudge uses it on Nyx Assassin, if timed correctly.
Phantom Assassin
* Though certainly not a "hard counter", Crystal Maiden's skillset (magical damage nukes) does pose a substantial threat to Phantom Assassin through the mid game, especially if followed up with engagement by her team.
* A quick use of Freezing Field directly after Phantom Strike can leave Phantom Assassin trapped inside the area of effect, capitalizing on Phantom Assassin's relatively low HP pool when she is not protected by Blur, and besides 
Skull Basher, Phantom Assassin hates buying disabling items like 
Scythe of Vyse or 
Eul's Scepter of Divinity.
* If Phantom Assassin chooses not to buy a Black King Bar relatively early, the attack slow from Freezing Field can greatly hinder the proc chance of Coup de Grace in a teamfight.
* However, Phantom Assassin's massive damage, and her tendency to build both Black King Bar and Skull Basher makes her a formidable foe the later the game goes, and fighting her without a team is almost never a good choice.
Phantom Assassin
* Crystal Maiden's low health pool and slow movement speed make her a tempting and easy target.
* However, it may be wise to build Black King Bar first before attempting to fight her alone, as she can disable you and retaliate with 
Freezing Field.
Nyx Assassin
* Crystal Maiden has a very bad movement speed, so Impale is easy to land against her. Furthermore, even while trapped by Frostbite, Nyx Assassin can still cast Impale.
* Crystal Maiden has very low armor, so Vendetta is very effective.
* Nyx Assassin has two ways to stop Freezing Field, provided she doesn't get a Black King Bar. He can either pop Spiked Carapace and simply walk into the field, or he can use Impale to interrupt the field, since Crystal Maiden has to channel it.
Additional:
* Spiked Carapace easily interrupts Freezing Field.
* 
Frostbite's damage over time sets up an easy Spiked Carapace stun.
* Crystal Maiden is extremely fragile and dies quickly to Nyx Assassin's burst damage.
Phantom Assassin
* 
Blink Strike does not grant Riki a mobility advantage over Phantom Assassin, as her Phantom Strike serves the same purpose, but with a higher range.
* A Carry Riki usually has a hard time dealing with Blur, as a Monkey King Bar or 
Bloodthorn are unfavourable item picks for him (or, even more unlikely, a Silver Edge).
* A Black King Bar is a very common pick for Phantom Assassin, fully countering 
Smoke Screen and 
Diffusal Blade while activated.
Nyx Assassin
* Mana Burn removes much-needed mana for 
Ball Lightning.
* Spiked Carapace triggers on 
Static Remnant for an easy stun.
Additional:
* Vendetta is capable of removing most of Storm Spirit's large mana pool, along with dealing heavy damage and quickly depleting his chances of escaping a gank or fight.
Nyx Assassin
* Nyx Assassin can simply activate Spiked Carapace while under many Invoker's abilities to stun him.
* Nyx Assassin takes advantage of Invoker's massive intelligence gain to do tons of damage using Mind Flare, as the spell does more damage based on the target's intelligence.
* Vendetta burns a large amount of Invoker's essential mana pool.
Nyx Assassin
* Nyx Assassin's Spiked Carapace will stun Leshrac when hit by any of his AOE abilities.
* Mind Flare deals high damage due to Leshrac's high intelligence gain.
* Vendetta burns a large amount of Leshrac's essential mana pool.
Phantom Assassin
* Heroes which rely exclusively on right clicks will struggle somewhat against Blinding Light: Phantom Assassin, Wraith King, Medusa
Phantom Assassin
* Heroes with teleports to escape Solar Blind and Will-O-Wisp: Phantom Assassin, Puck, Queen of Pain, Storm Spirit
Nyx Assassin
* Spiked Carapace can be used to reflect Illuminate damage and stun Keeper of the Light.
* Vendetta allows Nyx Assassin to follow Keeper of the Light around if he tries to split-push.
* Keeper of the Light is very squishy and will very quickly die to Vendetta and it's followup abilities.
Phantom Assassin
* Phantom Assassin can easily escape Lich's slows with Phantom Strike.
* Phantom Assassin's Coup De Grace can be used to burst down the squishy Lich.
Nyx Assassin
* Large area-of-effect with delay or require channeling: Enigma, Crystal Maiden, Invoker, Shadow Fiend, Pugna, Keeper of the Light, Dawnbreaker.
Phantom Assassin
* Heroes with Evasion or abilities that cause Tiny to miss like Phantom Assassin and Tinker are very effective because of Tiny's low attack speed. Additionally, Monkey King Bar is not a good item for Tiny because of its reliance on high attack speed to proc for magical damage.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Phantom Assassin
* Carries that can out damage Huskar will do well against him: Legion Commander, Faceless Void, Troll Warlord, Phantom Assassin.
Nyx Assassin
* Nyx Assassin can reflect Life Break with Spiked Carapace.
Phantom Assassin
* Assuming they have not bought anti-evasion items, attack-dependent heroes such as Ursa, Terrorblade or Lifestealer can be a minor threat for Phantom Assassin early in the game, and may even be completely dominated by her thanks to her evasion.
Phantom Assassin
* Heroes who rely on physical damage output to be effective will fare badly against Muerta's 
Pierce the Veil: Phantom Assassin, Terrorblade, Drow Ranger, Lifestealer, Anti-Mage, Alchemist, Lycan, Clinkz, Sniper.
Nyx Assassin
* Nyx Assassin's high burst damage, excellent ganking potential and multiple disables pose a threat to Muerta at all stages of the game.
* Mind Flare allows Nyx Assassin to take advantage of Muerta's high intelligence and make a short work of her low health.
* Spiked Carapace and Vendetta allow Nyx to escape or initiate well against Muerta's low mobility.
* As with most retaliation based abilities, Spiked Carapace can easily take advantage of 
Gunslinger's stray shots.
* However, Muerta is a natural Black King Bar wielder. And if she succeeds to activate it before Nyx Assassin can ambush her, he will go down very quickly against Muerta as Spiked Carapace cannot pierce through debuff immunity at all.
Phantom Assassin
* Hex abilities prevent attacking, ability and item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility: Doom, Disruptor with Aghanim's Scepter, Dazzle with Aghanim's Shard
Phantom Assassin
* Dazzle's lack of a true disable makes him a relatively vulnerable target for Phantom Assassin.
* Coup de Grace will often kill Dazzle's teammates before he has a chance to use 
Shallow Grave.
Nyx Assassin
* Heroes who rely on damage over time as Spiked Carapace can block and reflect only one instance of damage: Jakiro, Viper, Venomancer, Huskar, Ember Spirit, Dark Seer, Sand King, Doom, Dawnbreaker. However, this also means they are easily stunned.
Nyx Assassin
* With Vendetta, Nyx Assassin can move closely to Ember Spirit when he's farming with his Flame Guard and use Spiked Carapace with Impale to provide a reliable and long disable.
Additional:
* Spiked Carapace can be easily triggered by 
Flame Guard or Battle Fury, setting up a deadly Impale.
Nyx Assassin
* Heroes who build mana boosting items but have low mana regeneration are especially vulnerable against Mana Break and Mana Void: 
Timbersaw, Slark, Shadow Fiend, Clinkz, 
Bristleback Nyx Assassin, Magnus
Phantom Assassin
* Anti-Mage's low health pool making vulnerable to Phantom Assassin's burst damage and Coup De Grace critical strike, while Blink is on cooldown.
* Blur makes Anti-Mage unable to deal Mana Break to her.
* Phantom Assassin has low intelligence and low mana pool, making Mana Void do minimal damage.
Additional:
* Anti-Mage can easily withstand heavy magical bursts due to 
Counterspell, but he is still somewhat vulnerable to physical damage. Phantom Assassin's burst physical damage can destroy Anti-Mage while 
Blink is on cooldown or while he is stunned or hexed.
* Blur makes Anti-Mage unable to deal significant damage to her without buying Monkey King Bar, which means he cannot buy items to benefit his 
Mana Break.
* Phantom Assassin has an abysmal mana pool and intelligence gain, making Mana Break and 
Mana Void deal minimal damage.
Phantom Assassin
* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.
Nyx Assassin
* 
Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel 
Life Drain, making him easy to hit with Impale.
Additional:
* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mind Flare will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.
Phantom Assassin
* Heroes who rely on physical damage are easily negated by Ghost Shroud: Phantom Assassin, Wraith King, Juggernaut.
Nyx Assassin
* The huge physical damage taken from Vendetta will force Necrophos to use Ghost Shroud, which is good for a followup with Dagon and Ethereal Blade, both of which are common items on Nyx Assassin.
* Using Ghost Shroud also sets Necrophos up for a Mind Flare or Impale.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Nyx Assassin
* Impale and Spiked Carapace interrupts Upheaval with ease.
* Warlock's low health pool, mobility, and high intelligence gain makes him a prime target for Nyx Assassin's burst damage.
Phantom Assassin
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa, Warlock.
Nyx Assassin
* Vendetta disables Vengeance Aura and allows him to attack Vengeful Spirit with Impale and Mind Flare.
* Spiked Carapace is easy to use against a Wave of Terror or Magic Missile.
Phantom Assassin
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.
Nyx Assassin
* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
* 
Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
* An ill-timed 
Sanity's Eclipse and/or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used Black King Bar beforehand.
Additional:
* Outworld Destroyer's high intelligence makes him a good target for Mind Flare.
* If timed correctly, Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
* Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.
Phantom Assassin
* Heroes such as 
Lone Druid, 
Tidehunter and Viper can be very problematic for Phantom Assassin because they give her very little time to farm and become scary.
Nyx Assassin
* Ravage's travel time allows Nyx Assassin to easily stun Tidehunter with Spiked Carapace.
* Vendetta can instantly deplete Tidehunter's low mana pool, especially in the early game, potentially preventing Tidehunter from casting Ravage.
Phantom Assassin
* Heroes with disables that ignore spell immunity will render Phantom Assassin completely useless in teamfights throughout the game: Axe, Enigma, Vengeful Spirit, Doom, Bane, Beastmaster, Pudge, Medusa, Warlock.
Nyx Assassin
* Vendetta burns a significant amount of mana on hit, and the damage from the ability drains Medusa's mana pool even further.
* Due to the passive nature of Mystic Snake and Split Shot, it can possibly proc Nyx's Spiked Carapace if he's within range of Medusa's abilities and isn't invisible.
* Medusa lacks single target damage, making Nyx with Aghanim's Scepter extremely hard to deal with if Medusa is the team's main damage source.
Additional:
* With her passive 
Split Shot, Medusa can be easily interrupted by Spiked Carapace during combat, especially during her precious 
Stone Gaze.
* Mana Burn quickly destroys 
Mana Shield, especially if Medusa only increases her mana pool by bolstering intelligence (which has the added bonus of increasing Mana Burn's damage).
* Uncontrollable damage from 
Mystic Snake and Split Shot can trigger Spiked Carapace.
* Medusa lacks single target damage, making a Burrowed Nyx Assassin hard to kill.
Phantom Assassin
* While Phantom Assassin can kill Skywrath Mage in a few strikes, Skywrath Mage can also do the same to her if she is not careful.
* 
Arcane Bolt's long range and low cooldowns allows Skywrath Mage to severely harass Phantom Assassin in lane.
* 
Ancient Seal prevents Phantom Assassin from escaping or engaging with Phantom Strike.
* 
Mystic Flare's heavy magical damage nukes Phantom Assassin down quickly during the early to mid game.
Additional:
* While Phantom Assassin can kill Skywrath Mage in a few strikes, Skywrath Mage can also do the same to her if she is not careful.
* Arcane Bolt's long range and low cooldowns allows Skywrath Mage to severely harass Phantom Assassin in lane.
* Ancient Seal prevents Phantom Assassin from escaping or engaging with Phantom Strike.
* Mystic Flare's heavy magical damage nukes Phantom Assassin down quickly during the early to mid game.
Phantom Assassin
* Skywrath's pitiful defences also make him easy meat to heroes with high burst like Juggernaut, Lion, or Phantom Assassin, the latter occasionally downing a support Skywrath in a single Stifling Dagger.
Nyx Assassin
* Slow-moving projectiles: Skywrath Mage, Tinker, Necrophos
Additional:
* Skywrath Mage's low health makes him rather easy prey for Nyx Assassin and his lack of armor generally means he'll take the full brunt of a Vendetta strike.
* Mind Flare turns Skywrath Mage's high intelligence growth against him and deals heavy damage.
* Spiked Carapace gives Nyx some degree of protection against Skywrath's spells.
Phantom Assassin
* Phantom Assassin's Blur is useless against Windranger as she commonly buys items that require 
Javelin like Maelstrom, Monkey King Bar or Bloodthorn, and other than Stifling Dagger, Phantom Assassin has nothing else that can bypass Windrun.
* Additionally, Phantom Assassin doesn't like building Monkey King Bar because her crits are reliant on attack damage.
* Focus Fire can still deal considerable damage despite Blur's evasion due to the increased attack speed.
Additional:
* Phantom Assassin's Blur is useless against Windranger as she commonly buys items that require Javelin like Maelstrom, Monkey King Bar or Bloodthorn, and other than Stifling Dagger, Phantom Assassin has nothing else that can bypass Windrun.
* Additionally, Phantom Assassin doesn't like building Monkey King Bar because her crits are reliant on attack damage.
* Focus Fire can still deal considerable damage despite Blur's evasion due to the increased attack speed.
Nyx Assassin
* Many of Nyx Assassin's abilities are good against Windranger.
* Impale is great for stunning Windranger and allowing additional disables to be landed.
* Mind Flare is useful against Windranger's decent intelligence growth.
* Spiked Carapace is easy to use against Powershot.
* Vendetta allows Nyx Assassin to sneak up on and deal massive damage to Windranger without giving Windranger a chance to use Windrun to evade it.
* Nyx Assassin's item build allows him to easily deal with Windranger.
Phantom Assassin
* Phantom Assassin does not deal with early aggression very easily (especially when magical damage). A competent Batrider can make life very difficult with 
Sticky Napalm followed by any other spell.
Nyx Assassin
* Nyx can walk into Firefly with Spiked Carapace and stun Batrider if he has no Spell Immunity, even if Batrider is focusing on other enemy hero.
Phantom Assassin
* 
Sharpshooter disables both Blur and Coup De Grace, especially with the level 25 talent.
* Because Phantom Assassin is often reliant on critical strikes, Hoodwink can have enough time to simply move near a tree and escape with 
Scurry.
Additional:
* Sharpshooter disables both Blur and Coup De Grace, weakening her damage and survivability.
* Because Phantom Assassin is often reliant on critical strikes, Hoodwink can have enough time to simply move near a tree and escape with Scurry.
Nyx Assassin
* Nyx's Spiked Carapace can reflect the damage of Sharpshooter, instantly killing hoodwink. Nyx can also use Vendetta to position himself in such a way to screen allies from Sharpshooter and catch Hoodwink by surprise.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Phantom Assassin
* Fragile support heroes are all ideal targets for the Phantom Assassin. Heroes such as Lina and Witch Doctor are all prime targets that may not be able to react quickly and fight back due to Phantom Assassin's sudden appearance.
Phantom Assassin
* Puck relies mainly on magical burst damage, which Phantom Assassin is most vulnerable against.
* 
Phase Shift and 
Illusory Orb disjoint Stifling Dagger, also allowing to kite Phantom Assassin.
* 
Dream Coil will stun Phantom Assassin if she uses Phantom Strike to blink away.
Nyx Assassin
* Illusory Orb is easy to reflect with Spiked Carapace, either stunning Puck and setting up an easy Impale or forcing a premature Phase Shift.
* Puck is an intelligence hero that tends to build intelligence items, making it vulnerable to Mana Burn.
* An ill-timed Phase Shift can easily set Puck up to be stunned by Impale.
* Puck's low base armor and below average agility gain mean it is always susceptible to Vendetta.
Additional:
* Nyx Assassin can take advantage of every one of Puck's weaknesses. His entire skill set is very effective in countering Puck.
* Because Illusory Orb is such a slow moving projectile, Nyx Assassin can simply walk into the orb and activate Spiked Carapace, stunning Puck and setting up an easy Impale. This can be circumvented by using Phase Shift while the orb is traveling, however, that means that Puck cannot use Phase Shift to dodge any other skill nor use it to safely blink away from a fight.
* Puck is an intelligence hero that likes to build intelligence items such as Eul's Scepter of Divinity, Scythe of Vyse, and Dagon. This makes Mind Flare that much more deadly against Puck.
* An ill-timed Phase Shift can turn into an easy setup for Impale.
Phantom Assassin
* With Bloodthorn, Clinkz becomes a strong counter to heroes who rely on evasion and blind such as Windranger, Phantom Assassin, Troll Warlord and Keeper of the Light.
Phantom Assassin
* Heroes with high armor like 
Dragon Knight, or with abilities to cause attacks to miss like Phantom Assassin, Riki and Tinker will be hard to deal with, as Clinkz relies almost entirely on physical attacks.
Phantom Assassin
* Tinker can use Laser to save an ally or himself from Phantom Assassin's initiate Phantom Strike due to the blind, forcing her to use a Black King Bar to effectively initiate, Tinker can also use Warp Flare one he buys Aghanim's Shard to reverse Phantom Strike's blinking with Phantom Strike.
* Tinker almost never uses his physical attack, relying on his spell-spamming to deal damage which ignores Blur's Evasion
* Defense Matrix prevents Coup de Grace from triggering.
Nyx Assassin
* 
Heat-Seeking Missile allow easy Spiked Carapace stuns.
* As a fragile hero that relies on mana and intelligence items, Tinker is vulnerable to Mana Burn.
* Nyx Assassin's stuns can interrupt 
Rearm and leave Tinker helpless.
Additional:
* Nyx Assassin's whole skillset is good against Tinker:
* Impale prevents Tinker from blinding Nyx Assassin or fighting back, while giving Nyx' allies time to catch up to Tinker's position.
* Mind Flare generally deals more damage to intelligence based heroes like Tinker.
* Spiked Carapace can stun Tinker at a moment of Nyx Assassin's choosing if March of the Machines has been cast. It is also quite easy to time Spiked Carapace against Heat Seeking Missiles.
* Vendetta allows Nyx to approach Tinker in the trees or wait for him in common hiding spots and deal heavy damage to his low armor.
Phantom Assassin
* 
Laguna Blade is one of the best tools to kill Phantom Assassin before she can do anything in early-to-mid game due to its high magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage.
* Blur offers no protection against Lina's abilities. Likewise, Lina can counter Blur's evasion by buying either Silver Edge or Monkey King Bar.
* Lina just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can deal pure damage to Lina and disable 
Fiery Soul awhile Coup De Grace can deal serious damage to her even if she is spell immune, which may force Lina to buy Ethereal Blade to deal with Phantom Assassin.
Additional:
* Laguna Blade is one of the best tools to kill Phantom Assassin before she can do anything in early-to-mid game due to its high magical (pure with Laguna Blade damage is Pure and pierces Spell Immunity talent) burst damage.
* Blur offers no protection against Lina's abilities. Likewise, Lina can counter Blur's evasion by buying either Silver Edge or Monkey King Bar.
* Lina just has to be careful about Fan of Knives from Aghanim's Shard and Coup De Grace, as Fan of Knives can deal pure damage to Lina and disable Fiery Soul awhile Coup De Grace can deal serious damage to her even if she is spell immune, which may force Lina to buy Ethereal Blade to deal with Phantom Assassin.
Nyx Assassin
* Heroes who build Black King Bar as either core or situational item will be able to fight back against Nyx Assassin and freely attack him as Spiked Carapace cannot pierce spell immunity at all: Axe, Broodmother, Dawnbreaker, Enigma, Huskar, Jakiro, Legion Commander, Lina, Luna, Lycan, Slardar, Slark, Troll Warlord, Witch Doctor.
Phantom Assassin
* Fragile support heroes are all ideal targets for the Phantom Assassin. Heroes such as Lina and Witch Doctor are all prime targets that may not be able to react quickly and fight back due to Phantom Assassin's sudden appearance.
Nyx Assassin
* Mind Flare does tons of damage against Lina because of her high intelligence.
* Vendetta can deal heavy damage to Lina while also burning her mana, preventing Lina from casting her abilities.
* Spiked Carapace can easily be used to counter Lina's abilities because of their long cast animation, and could probably kill Lina outright if Laguna Blade is reflected. However, Lina can counter this with Eul's Scepter of Divinity, a common item on Lina.
Phantom Assassin
* Hex abilities prevent attacking, ability and item usage, which is a severe problem for Phantom Assassin as it prevents her from using Black King Bar, the one item that helps protect her against the aforementioned dangers. Doom and Shadow Demon with Aghanim's Scepter also disables Phantom Assassin's Evasion and Critical Strike, removing much of her damage and survivabaility: Doom, Disruptor with Aghanim's Scepter, Dazzle with Aghanim's Shard
Nyx Assassin
* Heroes that can pick you off: Clinkz, Nyx Assassin, Puck, Riki.
Phantom Assassin
* 
Fire Spirits applies a severe attack speed slow, severely hindering Phantom Assassin's damage output.
* Phantom Assassin cannot cast Phantom Strike on Phoenix during 
Supernova.
Additional:
* While her Phantom Strike does give limited extra attack speed, she cannot use the ability against the Phoenix Sun, and while her Blur may protect her from attacks, Phoenix's strong magical DPS burns away her small health pool quickly, and the attack speed slow makes her unable to fight back (provided she has no source of spell immunity).
Nyx Assassin
* Spiked Carapace reacts on any of the damage over time from Phoenix's abilities and can interrupt 
Sun Ray and 
Icarus Dive.
Phantom Assassin
* Heroes with illusions and summons can be hard for Phantom Assassin to deal with, as she lacks any AoE abilities to deal with them without items: Broodmother, Phantom Lancer, Chaos Knight, Lycan, Naga Siren, Shadow Shaman, Visage, Nature's Prophet, Terrorblade, Warlock, Wraith King.
Nyx Assassin
* Nyx Assassin, Bounty Hunter and Slark can all sneak up and kill Shadow Shaman, Nyx being particularly deadly. Shadow Shaman must watch out for Slark carefully, as he can break either (but not both unless he makes a mistake) of Shadow Shaman's disables, with 
Dark Pact and leap out of a serpent ward ring. These heroes, however, rely heavily on escape and are themselves not very durable and none of them can survive a full lockdown with Mass Serpent Ward. Having Sentry Wards can turn Shadow Shaman from prey to predator.
Phantom Assassin
*
Phantom Strike's extra attack speed will cause Phantom Assassin to trigger 
Counter Helix more often, which can be fatal for Phantom Assassin. Jumping on Axe with 
Phantom Strike is not a good idea for Phantom Assassin at all as it makes her a seriously easy target for a counter-initiation with 
Berserker's Call and 
Blade Mail.
Black King Bar, allowing him to lock down Phantom Assassin at any time.
Blade Mail. 
Berserker's Call can also affect Phantom Assassin even if she has 
Black King Bar active as 
Berserker's Call can fully pierce spell immunity, making 
Berserker's Call one of the best abilities in the game against heroes like Phantom Assassin who wants to kill opponents quickly without being interrupted.
Culling Blade can often kill Phantom Assassin before she can do anything due to her low health and strength gain. And every time 
Culling Blade successfully kills Phantom Assassin or any of her teammates, Axe gains permanent armor from it, which in combination with armor items that Axe often purchases like 
Blade Mail, 
Crimson Guard, 
Assault Cuirass and 
Shiva's Guard can make Phantom Assassin's attacks only tickle Axe. 
Aghanim's Shard upgraded 
Counter Helix can weaken Phantom Assassin's damage output, and if her attack damage is weak, 
Coup De Grace will also suffer from attack damage reduction as well.
Phantom Strike's extra attack speed will cause Phantom Assassin to trigger 
Counter Helix more often, which can be fatal for Phantom Assassin in the early game. Jumping on Axe with 
Phantom Strike is not a good idea for Phantom Assassin at all as it makes her a seriously easy target for a counter-initiation with 
Berserker's Call and 
Blade Mail.
Black King Bar, allowing him to lock down Phantom Assassin at any time.
Blade Mail. 
Berserker's Call can also affect Phantom Assassin even if she has 
Black King Bar active as 
Berserker's Call can fully pierce spell immunity, making 
Berserker's Call one of the best abilities in the game against heroes like Phantom Assassin who wants to kill opponents quickly without being interrupted.
Culling Blade can often kill Phantom Assassin before she can do anything due to her low health and strength gain. And every time 
Culling Blade successfully kills Phantom Assassin or any of her teammates, Axe gains permanent armor from it, which in combination with armour items that Axe often purchases like 
Blade Mail, 
Crimson Guard, 
Assault Cuirass and 
Shiva's Guard can make Phantom Assassin's attacks only tickle Axe.
* Most of Axe's abilities pierce
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe and may cause her to kill herself when used with
*
*
Additional:
*
* Most of Axe's abilities pierce
* Berserker's Call greatly reduces Phantom Assassin's ability to crit hard against Axe, and may cause her to kill herself when used with
*
Nyx Assassin
* A well-timed
Berserker's Call can expose Nyx Assassin while he is invisible with Vendetta, and prevent him from using Spiked Carapace.
Battle Hunger's damage over time to minimialize effects of Spiked Carapace.
Heart of Tarrasque wielder, which can completely eliminate any chance for Nyx Assassin to kill Axe alone.
Culling Blade can often kill Nyx Assassin as he is very fragile and vulnerable to damage while Spiked Carapace is on cooldown.
Berserker's Call can expose Nyx Assassin while he is invisible with 
Vendetta, and prevent him from using 
Spiked Carapace.
Battle Hunger's damage over time to minimialize effects of 
Spiked Carapace.
Heart of Tarrasque wielder, which can completely eliminate any chance for Nyx Assassin to kill Axe alone.
Culling Blade can often kill Nyx Assassin as he is very fragile and vulnerable to damage while Spiked Carapace is on cooldown.
* Axe can use
* Axe's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off. Especially since Axe is a common
*
Additional:
* A well-timed
* Axe can use
* Axe's high health also allows him to easily shrug off Nyx Assassin's burst damage and fend him off. Especially since Axe is a common
*