* Heroes with mana burn: Nyx Assassin, Invoker, Outworld Destroyer, Pugna, Lion

* A combination of Soulbind and Phantom's Embrace can prevent Anti-Mage from casting spells.
* If Grimstroke has Aghanim's Scepter, Dark Portrait can reflect Anti-Mage's Mana Break, making it useful in team fights.

* Heroes who rely heavily on melee attacks and lack early spell immunity are easily blocked and interrupted by Ink Swell: Lycan, Ursa, Troll Warlord.

* Heroes who are reliant on illusions or summons: Chaos Knight, Broodmother, Naga Siren.

* Hard-hitters who relies mostly on raw stats or good passive and therefore make a perfect target for Dark Portrait: Naga Siren, Faceless Void, Terrorblade, Luna, Anti-Mage

* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw.
* Decrepify can further increase all the magical damage done to Timbersaw, bypassing the enhanced physical resistance he can get from Reactive Armor.
Additional:
* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw, especially when combined with Decrepify.

* Timbersaw relies heavily on his abilities so Phantom's Embrace's silence makes it more difficult for him.
* Timbersaw cannot use Return Chakram or attack the phantom during Phantom's Embrace, forcing him to take full damage and refreshes Phantom's Embrace's cooldown.
Additional:
* Timbersaw is completely powerless against Phantom's Embrace if Chakram is out.

* Nether Ward causes Death Pulse to actually damage Necrophos rather than heal him. Meanwhile, Reaper Scythe's gigantic mana cost while Necrophos is near the Nether Ward can often instantly kill him.
* Nether Blast and Life Drain both make quick work of Necrophos's small healthpool, especially during Ghost Shroud. The latter also makes him an unappealing target for Reaper's Scythe, and can often force Necrophos to use it defensively as he has no other means of interrupting his channeling.

* Ghost Shroud amplifies damage taken from all of Grimstroke's abilities. Necrophos is particularly vulnerable to Ink Swell and Phantom's Embrace while in Ghost Shroud.
* Death Pulse works against Necrophos in lane by keeping his creeps alive and add damage to Stroke of Fate.

* Nether Blast will still hit Slark even if he is hidden during Shadow Dance.
* Even though Pugna can rarely target Slark directly with Decrepify, he can still use it defensively on an ally to prevent Slark from getting stacks.
* Despite being somewhat easy to break with Pounce, Pugna can damage Slark and provide vision over him with Life Drain.

* Phantom's Embrace cannot be dispelled by Slark's Dark Pact, and will cause him to suffer damage if he doesn't kill Phantom fast enough.
* Soulbind also cannot be dispelled by Slark's Dark Pact, and will cause Slark to suffer from a single-targeted ability used on his ally that is also affected by it.

* Decrepify prevents Faceless Void from attacking trapped allies inside Chronosphere, wasting a large portion of its duration if Faceless Void can't dispel it.

* Soulbind pierces spell immunity and prevents Faceless Void from escaping with Time Walk.

* As Terrorblade's damage output comes mainly from direct attacks, he will struggle greatly against heroes who have abilities that give evasion, trigger on attack or which can disarm an enemy hero: Centaur Warrunner, Hoodwink, Huskar, Invoker, Leshrac with Nihilism from Aghanim's Scepter, Lifestealer with Aghanim's Scepter upgraded Infest, Pangolier, Phantom Assassin, Pugna, Techies, Windranger etc.

* Terrorblade's lack of escape mechanisms makes it hard for him to escape both Ink Swell and Stroke of Fate.
* Phantom's Embrace's silence will also prevent him from casting Sunder to save himself.

* Troll Warlord can't switch targets at will, in order to build Fervor stacks, which makes it easy to use Decrepify in order to save allies
* During Battle Trance, Pugna can easily use Nether Blast, Decrepify and Life Drain on him

* Heroes who rely heavily on melee attacks and lack early spell immunity are easily blocked and interrupted by Ink Swell: Lycan, Ursa, Troll Warlord.

* Enigma's abilities have a huge mana cost, meaning that Nether Ward will deal a lot of damage to Enigma.
* Pugna can heal allies trapped inside Black Hole thanks to Life Drain, Pugna can also damage multiple of Enigma's allies around him with Life Drain when he casts it on Aghanim's Shard upgraded Nether Ward during teamfight.
* Nether Blast can easily kill Eidolons, especially when Enigma is pushing.
* Even though Pugna cannot cancel Black Hole on his own, smart Pugna can buy Orchid Malevolence to stop Enigma from channeling Black Hole and make him more vulnerable to counter-attacks with Decrepify and Life Drain.
Additional:
* Enigma's abilities have a huge mana cost, meaning that Nether Ward will deal a lot of damage to Enigma.
* Pugna can heal allies trapped inside Black Hole thanks to Life Drain.
* Nether Blast can easily kill Eidolons, especially when Enigma is pushing.

* Heroes with powerful channeling abilities are easily interrupted by Phantom's Embrace: Bane, Pudge, Witch Doctor, Crystal Maiden, Enigma.

* Pugna: Decrepify prevent the Spirit bear from attacking or protect allies from it.

* Grimstroke's Soulbind will always reliably connect onto both of them if they are close together.

* Pugna's Decrepify prevents the target from taking physical damage or doing damage, which poses a huge problem for Lycan, as he mainly deals physical damage.

* Heroes who rely heavily on melee attacks and lack early spell immunity are easily blocked and interrupted by Ink Swell: Lycan, Ursa, Troll Warlord.

Additional:
* Stroke of Fate deals more damage when it hits more targets which makes it very effective in dealing with Lycan and his units.
* Soulbind prevents Lycan from running away and makes him very easy to deal with.

* Heroes that commonly attack ethereal units will not have any problems against Muerta's Pierce The Veil: Tinker, Jakiro, Lina, Luna, Pugna or Ogre Magi, Enigma, Batrider, Techies, Broodmother, Dawnbreaker, Shadow Shaman, Bane, Tinker, Venomancer, Arc Warden.

* Any long duration disables that can pierce through both, Pierce The Veil and Black King Bar are devastating against Muerta: Enigma's Black Hole, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Naga Siren's Aghanim's Scepter upgraded Ensnare and Reel In from Aghanim's Scepter, Jakiro's Aghanim's Scepter upgraded Macropyre, Bane's Fiend's Grip, Pudge's Dismember, Batrider's Flaming Lasso, Beastmaster's Primal Roar, Grimstroke's Soulbind, Medusa's Stone Gaze, Magnus's Reverse Polarity.

* Heroes with magical or pure damage output will not have any problems against Atrophy Aura at all: Luna, Lina, Jakiro, Pugna, Bane, Snapfire, Muerta, Nyx Assassin, Enigma, Tinker, Witch Doctor, Zeus, Crystal Maiden.

* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: Luna's Aghanim's Scepter upgraded Eclipse, Dawnbreaker's Solar Guardian, Axe's Berserker's Call, Mars's Arena of Blood, Jakiro's Macropyre, Dual Breath and Ice Path, Naga Siren's Song of the Siren, Razor's Eye of the Storm and Plasma Field, Lina's Light Strike Array, Broodmother's Spinner's Snare from Aghanim's Scepter, Elder Titan's Earth Splitter and Echo Stomp, Alchemist's Unstable Concoction and Acid Spray, Queen of Pain's Sonic Wave, Dark Seer's Wall of Replica and Vacuum, Venomancer's Noxious Plague and Poison Nova from Aghanim's Scepter, Oracle's Fortune's End and Rain of Destiny from Aghanim's Shard, Bloodseeker's Blood Rite, Enigma's Black Hole and Midnight Pulse, Shadow Fiend's Requiem of Souls, Batrider's Aghanim's Scepter upgraded Flaming Lasso, Firefly, Flamebreak and Sticky Napalm, Ancient Apparition's Ice Blast, Sand King's Epicenter, Sand Storm and Burrowstrike, Gyrocopter's Call Down, Ember Spirit's Sleight of Fist, Death Prophet's Exorcism and Silence, Monkey King's Wukong's Command, Crystal Maiden's Freezing Field, Muerta's The Calling, Medusa's Stone Gaze, Zeus's Nimbus from Aghanim's Scepter. Dark Willow's Bramble Maze, Pangolier's Swashbuckle, Grimstroke's Soulbind, Ink Swell and Stroke of Fate, Earthshaker's Echo Slam and Fissure, Puck's Dream Coil and Waning Rift, Winter Wyvern's Winter's Curse, Magnus's Reverse Polarity.

* Nether Blast can deal high damage to Chen and clear waves of his creeps.
* Decrepify can be used to waste the duration of Penitence.
* Nether Ward can discourage Chen from using Penitence, Holy Persuasion and Hand of God due to their fairly high mana costs.
* Life Drain can often kill Chen or any of his allies before he can save them with Hand of God thanks to it's high damage and low cooldown.

* Amazingly, Enchantress has even lower health than Pugna. Though she does pack quite a punch through Impetus, she can't use it if she is under Decrepify.
* Pugna's Magical DPS is way greater than the heal from Nature's Attendants, which will also harm her quite a bit if she's next to Nether Ward.

* Phantom's Embrace silences Viscous Nasal Goo and Quill Spray.
* Ink Swell stuns Bristleback and gets allies in position faster with increased movement speed to attack his front, countering his passive ability.

* Arc Warden can't use Magnetic Field to stall the damage of Nether Blast on towers, but he can buy Aghanim's Shard to diminish its damage.
* Arc Warden has no innate disables to stop Life Drain and Decrepify
* The short cooldown of both Life Drain and Decrepify also means Pugna can deal with Arc Warden and Arc Warden's clone simultaneously most of the time
* A good Pugna looks to end the match early while Arc Warden, a very item reliant hero, thrives in longer matches.

* Nether Blast, Decrepify and Life Drain deal high magical damage and bypasses Bulwark.
* Nether Ward reduces the amount of abilities Mars can use during fights and forces Mars to be careful about the heavy mana cost of Arena Of Blood.
* Pugna is one of few heroes that can contest Mars' ability to push and defend towers early on.

* Phantom's Embrace can silence Crystal Maiden and disrupt Freezing Field's channeling. Her slow movement speed and fragile nature will also make her an easy target for Stroke of Fate and Ink Swell.

* Decrepify prevents Shadow Fiend from attacking for its duration, potentially preventing him from getting a kill.
* Nether Ward can do heavy damage to Shadow Fiend if he tries to cast his Requiem of Souls and his Shadowraze.
Additional:
* Decrepify prevents Shadow Fiend from attacking for its duration, potentially preventing him from getting a kill.
* Nether Ward can do heavy damage to Shadow Fiend if he tries to cast his Requiem of Souls or spam Shadowraze.

* Nether Blast is one of the best tower pushing abilities in the game, with a low cooldown. A competent Pugna will (at the very least) destroy tier 2 towers and make space for his team before Spectre can finally come online.
* Spectre's spells, while not spammable, have a fairly high mana cost, so Nether Ward can be fairly damaging to Spectre early game. The mana degen will also dampen Spectre's early game power significantly.
* Once Pugna gets Aghanim's Scepter, he can spam Life Drain on any illusion Spectre summons, whether it'd be from Haunt, Manta Style, or some other means.
* In addition, Pugna can disable Spectre's Desolate ability (although its damage is pure, it requires physical attacks) with his Decrepify ability, leaving Spectre only with Spectral Dagger.

* Pugna can save allies with both healing or by making them ethereal but needs to be careful of Sven's Aghanim's Scepter purge.

* Pugna's Decrepify allows him to save allies from being ganked by Viper, since Viper mostly relies on direct attacks in order to deal damage.
* Nether Ward can discourage Viper from spamming his abilities.
* Viper's damage over time is not enough to kill Pugna as he will have more than enough time to save himself (or his allies) with Life Drain and Viper has no solutions to cancel it.
* Pugna has no passive abilities, which renders Nethertoxin nearly useless.

* Pugna easily copes on the line with the Keeper of the Light push with his Nether Blast, and in addition to Nether Ward, the Keeper of the Light is not able to throw Illuminate on creeps for a long time, so Pugna earns more gold and a level on the line
Additional:
* Pugna easily copes on the line with the Keeper of the Light push with his Nether Blast, and in addition to Nether Ward, the Keeper of the Light is not able to throw Illuminate on creeps for a long time, so Pugna earns more gold and a level on the line

* Decrepify can be used on allies to prevent them from attacking Axe and triggering Counter Helix during Berserker's Call. He can also cast it on Axe to prevent anyone from attacking him.
* Life Drain can be used to heal himself or allies caught in Berserker's Call, preventing them from dropping low enough for Axe to kill them with Culling Blade.

* Nether Ward punishes Leshrac's constant mana usage from spamming spells.
* Leshrac needs to be in the thick of the fight to deal damage, and so cannot escape from Nether Blast nor Life Drain easily.
Additional:
* Leshrac needs to be close to target in order to do damage, Pugna can outrun Leshrac with ease due to his superior movement speed.
* Split Earth can also be hard to land on Pugna for the same reason.
* Leshrac uses huge amounts of mana to do damage, Nether Ward forces him to either not contribute in a fight or kill himself in the process.

* Nether Ward on its own can greatly hinder Invoker from casting many of his abilities, at least until he gets a significant amount of HP or is under the protection of spell immunity from Black King Bar
* Life Drain provides True sight, revealing Invoker through Ghost Walk, and forcing him or his allies to use an ability or item to interrupt its channeling
* Outside of Nether Ward's range, Invoker shall have the advantage, as Invoker has Tornado to purge Pugna's Decrepify when it is used defensively, Tornado or Cold Snap to prevent Pugna from channeling Life Drain
* A poorly used Decrepify on Pugna's allies means Invoker's abilities can be used to deal more damage to them.
Additional:
* Because Invoker relies on casting a large amount of spells to contribute to fights, Nether Ward can force him to not cast anything at all or take a large amount of damage to cast spells.

* Phantom's Embrace and Soulbind prevent Weaver from using Shukuchi or Time Lapse to escape.
* Ink Swell discourages Weaver from moving through and damaging allies with Shukuchi.

* Decrepify on either hero stops Legion Commander from completing a Duel, and dissuades her from initiating Duels on ethereal allies.
* Life Drain can help Pugna's teammates win a fight, either by killing Legion Commander or replenishing her target's health.
Additional:
* Decrepify prevents Legion Commander from attacking allies during Duel, regardless if it's used on her or on the ally .
* Pugna can easily cast Decrepify, Nether Blast and Life Drain on Legion during the 4/4.75/5.5/8 seconds of duel

* Soulbind can target both Io and its Tethered ally, allowing Grimstroke and his team to target both with single target spells. Should Io try to Relocate, Phantom's Embrace can stop its channel to prevent escape.
Additional:
* Grimstroke can catch Io and his Tethered ally easily with Soulbind as Io has a tendency to Tether himself with an ally frequently, which also makes them easier targets for Soulbind.
* Io is highly vulnerable to disables. Hence, Grimstroke's Phantom's Embrace is a great ability to hinder Io's potential.

* Nether Ward can do a ton of damage to Disruptor because of his high mana costs.
* Life Drain can be used to heal an ally trapped by Static Storm-Kinetic Field combo (if Pugna is not a target).

* Cold Embrace is a death sentence against Pugna, since its the perfect setup for all his abilities, especially Life Drain.
* Decrepify can be cast to save the ally under Winter's Curse effect, wasting most of its duration.
* Winter Wyvern's abilities require a lot of mana, allowing Nether Ward to deal lots of damage.

* Decrepify prevents Omnislash damage, until Juggernaut gets a Nullifier.
* Without a disable, Pugna's high movement speed makes it harder to chase him with Blade Fury.
* Juggernaut has low mana and his skills cost large amount of mana. Nether Ward will hurt him more and even worse, the damage from the ward is inflicted before the Spell immunity provided by Blade Fury.
Additional:
* Decrepify is the perfect tool against Omnislash until he gets a Nullifier, and even then he will probably waste a couple of slashes before he uses it.
* Without an extra disable, Pugna's high movement speed makes it impossible to chase him with Blade Fury.
* Unlike some other carries like Slark or Phantom Assassin, Juggernaut's spells cost a hefty amount of mana and he will seriously get hurt by Nether Ward. Don't forget the damage from the ward is inflicted before the spell immunity is provided by Blade Fury.

* Pugna can turn out to be an effective hero against Dazzle due to the fact that he does not allow him to extend his Poison Touch with his Decrepify, which is why Dazzle cannot keep the enemy under prolonged deceleration.
* Pugna has a very strong ability against casters with a small health reserve - Nether Ward, which is why heroes like Dazzle will not be able to constantly throw their Poison Touch Bad Juju and Shadow Wave at enemies under the action of Nether Ward or will be forced to take a lot of damage
Additional:
* Pugna can turn out to be an effective hero against Dazzle due to the fact that he does not allow him to extend his Poison Touch with his Decrepify, which is why Dazzle cannot keep the enemy under prolonged deceleration.
* Pugna has a very strong ability against casters with a small health reserve - Nether Ward, which is why heroes like Dazzle will not be able to constantly throw their Poison Touch Bad Juju and Shadow Wave at enemies under the action of Nether Ward or will be forced to take a lot of damage

* Heroes who are reliant on illusions or summons: Chaos Knight, Broodmother, Naga Siren.

* Windranger heavily relies on her abilities for any form of tactical advantage and damage. A well timed silence will make her useless: Puck,Silencer, Death Prophet, Skywrath Mage, Drow Ranger, Earth Spirit, Grimstroke.

* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: Axe, Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.

* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with Hookshot) can easily avoid Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.

* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.

* Nether Ward will be problematic for heavy nukers and spammers like Skywrath Mage, Lina, Lion and Invoker, but Pugna must not use Decrepify defensively against them as he will be helping them out more than anything.

* Heroes who are reliant on physical damage will be nullified by Decrepify: Riki, Wraith King, Juggernaut.

* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: Sven, Omniknight, Enigma, Luna, Naga Siren, Mars, Jakiro, Venomancer, Elder Titan, Faceless Void, Rubick, Keeper of the Light, Pugna, Invoker, Spectre, Alchemist, Treant Protector, Lina, Oracle, Zeus, Shadow Shaman, Phoenix, Razor, Huskar, Batrider, Kunkka, Tidehunter, Wraith King, Sand King, Medusa, Dawnbreaker.

* Heroes with powerful channeling abilities are easily interrupted by Phantom's Embrace: Bane, Pudge, Witch Doctor, Crystal Maiden, Enigma.

* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.

* Heroes who are reliant on physical damage will be nullified by Decrepify: Riki, Wraith King, Juggernaut.

* Heroes with powerful channeling abilities are easily interrupted by Phantom's Embrace: Bane, Pudge, Witch Doctor, Crystal Maiden, Enigma.

* Heroes that can punish aggressive heroes, such as: Leshrac, Shadow Demon, Pugna, Death Prophet.

* Heroes with area of effect abilities that increase in power based on the number of units struck: Earthshaker, Legion Commander, Grimstroke.

Additional:
* Stroke of Fate can deal heavy damage to Broodmother and her spiders, and with enough spiders it can kill her instantly.
* Phantom's Embrace provides vision on Broodmother when she's fleeing into the trees.

* Any heroes with high intelligence, such as Invoker and Pugna.

* Pugna's Decrepify can render Templar Assassin's physical attacks useless.
* Pugna can also cast Life Drain on Templar Assassin, burning her Refraction instances.
* On the other hand, Pugna generally has low health and armor. Use this to your advantage.

* Soulbind ignores spell immunity, forcing Pangolier to roll in place during his ultimate as well as anchoring the other victim to his vicinity.

* Due to the high mana cost of his spells and the low cool down of them, Nether Ward can seriously damage Skywrath Mage if he isn't careful.
* Skywrath Mage's fragility makes him very susceptible to Pugna's high burst damage.
Additional:
* Nether Ward will make Skywrath Mage next to useless in fights, as his low hp pool will not allow him to sustain through the damage of the ward should he choose to cast spells. Be wary though that Skywrath's huge burst will make very quick work of Pugna's low hp should the ward be destroyed, and Decrepify won't help Pugna at all.

* Even though Pugna's low HP means that he can be quickly burst down, his Nether Ward heavily punishes casters whose spells cost a lot of mana, like Zeus. Casting 4 of his active spells, including Nimbus, close to an enhanced level 4 Nether Ward, can make the ward deal up to 1750 magical damage.
* Decrepify can further increase the damage dealt by Nether Ward upon Zeus. However, if used on Pugna himself or on one of his allies, it will amplify the damage done by Zeus' abilities.

* Nether Ward discourages Tinker from using abilities and items due to its high damage against heavy mana usage.

* Stroke of Fate's damage increases the more units are hit by it, making it effective against Phantom Lancer's army of illusions.
* Phantom's Embrace and Ink Swell's stun can prevent Phantom Lancer from escaping with Doppelganger if properly timed.
* If he has already used Doppelganger, Soulbind can tie Phantom Lancer to one of his own illusions to keep him in place, or to ensure a kill if Grimstroke's team is unsure which one is the real hero.
Additional:
* Stroke of Fate clears Phantom Lancer's illusion easily as it deals bonus damage to more targets.
* Ink Swell can be used on an allied hero or Grimstoke himself to stun Phantom Lancer and his illusions.
* Soulbind has an undispellable debuff that can be used to mark the real Phantom Lancer. It also prevents him from using Doppelganger.

* Pugna's Nether Ward damages Sand King when he channels Epicenter, preventing him from using Blink Dagger afterward.

* Nether Ward will be problematic for heavy nukers and spammers like Skywrath Mage, Lina, Lion and Invoker, but Pugna must not use Decrepify defensively against them as he will be helping them out more than anything.

* Heroes with powerful channeling abilities are easily interrupted by Phantom's Embrace: Bane, Pudge, Witch Doctor, Crystal Maiden, Enigma.

* All of Pugna's abilities are active, making Demonic Purge break from Aghanim's Scepter useless.
* Nether Ward punishes Shadow Demon's constant mana usage from spamming spells, especially Shadow Poison.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Nether Blast for the enemy.
* Life Drain can be used to heal Pugna or an ally to save them from Shadow Demon's abilities.
* However, it can be cancelled by Disruption unless Pugna buys defensive items.