Pugna
* Pugna's squishiness and lack of mobility make him easy prey for a Hookshot initiation.
* Clockwerk's high health, low mana costs, and lack of reliance on Blink Dagger make 
Nether Ward ineffective.
* Battery Assault shuts down 
Aghanim's Scepter upgraded 
Life Drain, as the repeated ministuns prevent Pugna from channeling for an extended length of time.
Additional:
* Clockwerk loves to 
Hookshot low health, immobile targets like Pugna.
* Pugna's Life Drain gets immediately and repeatedly (if an Aghanim's Scepter was purchased) cancelled due to 
Battery Assault, especially if Pugna is trapped inside 
Power Cogs.
* Clockwerk also loves to build 
Blade Mail, which will deal more damage to Pugna than Clockwerk due to Pugna's low health pool.
* Finally, both Hookshot and 
Rocket Flare can allow him to finish off Pugna out of range of his Nether Ward.
Meepo
* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as 
Batrider, 
Beastmaster, 
Pudge and 
Clockwerk.
Pugna
* Heroes with channeled abilities can be interrupted by a long-range Fissure: 
Crystal Maiden, 
Witch Doctor, 
Bane, 
Pugna, Pudge.
Meepo
* Each of Meepo's clones count as real heroes, meaning that an Echo Slam hitting them will deal catastrophic damage to Meepo and his team.
* Eathshaker's AoE stuns can interrupt Meepo's 
Poof cast animation.
Additional:
* 
Echo Slam will deal catastrophic damage against a cluster of Meepos and anyone nearby.
* 
Aftershock allows Earthshaker's abilities to potentially stun any number of Meepos for a fairly long duration, often enough to finish one off.
Pugna
* Puck can dodge 
Nether Blast and Life Drain with his Phase Shift, easily avoiding Pugna's strong burst magic damage.
* 
Waning Rift's silence allows Puck and its teammates to easily deal with Pugna, which cannot do the same to it, because with Puck it will be easy to avoid such an attack from the 
Decrepify.
* The Puck's combo: Waning Rift + 
Illusory Orb + 
Dream Coil doesn't have a huge amount of damage to feel the damage of the Pugna from Nether Ward, however, it may be quite enough to kill the Pugna solo at an early stage of the game with 
Witch Blade
Additional:
* Puck easily dodges the Nether Blast and the Pugna Life Drain with his 
Phase Shift, which is why he can easily avoid his strong magic damage
* The Puck's silence from the Waning Rift ability allows her team to easily cope with the Pugna, which cannot be said about the Pugna, because with the Puck it will be easy to avoid such an attack from the Decrepify
* The Puck's combo: Waning Rift + Illusory Orb + Dream Coil doesn't have a huge amount of damage to feel the damage of the Pugna from Nether Ward, however, it may be quite enough to kill the Pugna solo at an early stage of the game with Witch Blade
Meepo
* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as 
Enigma, 
Invoker, 
Magnus, 
Puck, and 
Sand King.
Pugna
* Heroes who build a Black King Bar (or have any sources of spell immunity) to channel abilities/items can still get interrupted by Dismember: Enigma, 
Juggernaut, 
Phantom Assassin, Pugna, 
Elder Titan.
Meepo
* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.
Pugna
* All of Pugna's damage is magical, which can get blocked by 
Fate's Edict's 100% magic resistance.
* Oracle has two abilities that apply a dispel, which can easily remove Decrepify on his ally or Oracle.
Pugna
* If Ursa uses 
Enrage, Pugna's Life Drain is next to worthless against him, due to Ursa taking 80% less damage, therefor Pugna heals by only 20% of the damage that the spell normally deals.
* It also dispels Decrepify, Even if you wait until he casted it, he can still dispel it with Shard upgraded 
Earthshock
* Ursa also commonly builds 
Skull Basher. With his high Attack Speed from 
Overpower. he can easily cancel Life Drain
* If Decrepify is defensivly casted, Ursa can still cast Earthshock both to slow you, and to deal amplified magic damage. He also commonly builds a 
Nullifier
* If Ursa jumps on you with a 
Blink Dagger he can easily wipe you out with Overpower.
* Ursa's Overpower can destroy a full health Nether Ward and still have a few swipes leftover, Also Ursa's low mana spells means he takes negligible damage from the Nether ward anyway.
* Ursa is also a common 
Diffusal Blade carrier, using it to both amplify his damage, but as his primary way to catch fleeing heroes
* Pugna is also the primary target of Ursa, due to him being both quite squishy, and a serious threat to his team, Ursa prioritizes the weakest link as 
Fury Swipes stacking damage will quickly demolish them, allowing Ursa to safely switch heroes
Meepo
* Poof won't damage Medusa and she can use Stone Gaze to disable all of Meepo's clones.
* Mystic Snake will easily become the bane of Meepo early game.
Meepo
* Meepo lacks the disengages to escape a well-timed Echo Stomp, in particular if Elder Titan is his current target.
* Clones are counted as heroes, increasing massively the power of 
Astral Spirit's buffs, including Aghanim's Scepter's spell immunity buff.
* Meepo relies heavily on high agility and his mediocre strength gain makes him a very prized target for Natural Order.
* Meepo and his clones like to group up to hunt and kill in teamfights or ganks and can be easily disabled together with Echo Stomp.
Additional:
* 
Echo Stomp can completely disable multiple Meepos for 5 seconds.
* Astral Spirit will affect Meepo clones, as they don’t count as illusions. Elder Titan can receive a massive amount of damage, armor and movement speed from each Meepo.
* With 
Natural Order, Elder Titan’s mere existence causes Meepo to be disadvantaged, due to the aura that completely negates his base armor and magic resistance. Combining Astral Spirit with Natural Order allows Elder Titan to easily kill any Meepo within a second, depending on how much damage he gains from Astral Spirit. This is highly detrimental for Meepo as he is prone to buying items that grant agility like 
Disperser and 
Eye of Skadi.
* 
Earth Splitter deals over 30%/40%/50% of each Meepo’s max hp, and is even stronger if the Meepos are near Elder Titan due to Natural Order.
Meepo
* With Nether Swap, Vengeful Spirit can isolate one of the Meepos, making him an easier kill for the team.
* Her Magic Missile gives her an easy way to cancel Meepo's Poof, preventing isolated Meepos from fleeing.
Meepo
* Dark Seer can take great advantage of 
Divided We Stand by putting an Ion Shell on a clone in order to harass them effectively.
* Vacuum can take a single Meepo and disable him for Dark Seer and his teammates to take out.
Meepo
* Poof combo puts all of the Meepos very close together, making them vulnerable to Frost Blast's AoE slow and multiple bounces from Chain Frost.
Meepo
* Every Meepo clone adds to Thirst's bonuses.
* Bloodseeker can chase down retreating clones when Meepo tries to cycle weaker clones away from combat.
Meepo
* Fatal Bonds links the Meepos together, which combined with area of effect damage or Cleave will be devastating.
Meepo
* X Marks the Spot is good to prevent a single meepo from escaping from a deadly situation.
* Tidebringer, Torrent and Ghostship destroys Meepo's clones.
Additional:
* 
Tidebringer's cleave damage can wear down Meepo's clones quickly. It can also give Meepo problems in the lane, due to his melee range and initially low health pool.
* 
Ghostship and 
Torrent can effectively disable Meepo while dealing heavy damage.
* 
X Marks the Spot prevents attempts to escape using Poof.
Meepo
* 
Focus Fire can quickly attack target Meepo or clones instanly. Additionally, Windranger can use combinated 
Shackleshot and Focus Fire since Poof wrong landing and stunned from Shackleshot affected Meepo and clones collateral damege from Focus Fire.
* Escaping from 
Windrun make Earthbind roots can not reach.
Meepo
* Tether helps Io escape from Earthbind even if Meepo has Blink Dagger.
* Io's Spirits can pressure Meepo while laning and will usually hit at least one of his clones.
Meepo
* Casting Bramble Maze on top of Meepo guarantees a root, as it is nearly impossible to leave the thorns with all of Meepo's clones.
* Terrorize and Cursed Crown offer great disables against the grouped Meepos and can prevent them from using Poof to escape.
Pugna
* Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel Life Drain, making him easy to hit with Impale.
Additional:
* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added 
Dagon. 
Mind Flare will deal a large amount of damage in particular, especially in the late game.
* 
Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in 
Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for 
Impale.
Pugna
* Pugna is very reliant on his abilities for damage which Silencer can take advantage off. But he has to be careful around the Nether Ward as Silencer's abilities cost a lot of mana to use.
Pugna
* Primal Beast has multiple ways to cancel Life Drain very quickly.
* Pugna has a very low strength gain and as a support does not have much gold to buy health items, making him vulnerable to Primal Beast's onslaught of magical damage.
* Ironically, Decrepify actually just increases Primal Beast's damage on the targeted ally if Trample is activated. However, it can be used to slow him down and prevent any further Trample damage.
Pugna
* Life Drain does not instantly kill the illusions from 
Phantasm
* 
Chaos Bolt and 
Reality Rift can easily interrupt the channeling from Life Drain.
* Reality Rift makes it harder for Pugna to keep his distance between Chaos Knight.
* Nether Ward barely deals any significant damage on Chaos Knight as Chaos Knight's abilities do not cost a lot of mana
* The overwhelming damage of Chaos Knight and his illusions will do a quick work on Pugna's poor HP pool, or safely remove the Nether Ward from the battlefield.
Pugna
* Sniper's huge range makes him an unviable target to use Life Drain on, forcing Pugna to risk playing out of position to use it on Sniper.
* Sniper's 
Shrapnel can be used to provide vision on Nether Ward, and his range allows him to easily take it out.
* A clumsy Pugna may accidentally boost Sniper's Shrapnel and 
Assassinate damages if he recklessly uses Decrepify on himself or his allies.
Meepo
* Flak Cannon and Call Down will shred Meepo's clones.
* Homing Missile can catch and single out retreating Meepos, making them an easy kill.
Meepo
* Quill Spray usually hits Meepo's clones, although Bristleback cannot turn his back when rooted with 
Earthbind.
Pugna
* Pugna's low health and reliance on channeled abilities make him very vulnerable to Tusk, although Pugna can win in a straight up 1v1 later in the game.
Pugna
* Heroes who rely on channeling abilities can be interrupted in teamfights by Rolling Thunder: Crystal Maiden, Pugna, Witch Doctor
Meepo
* Pangolier's arsenal deals heavy damage in a wide area, make him deadly even for a Meepo with a high magic resistance.
* 
Shield Crash can easily give him a ridiculous 80% damage resistance (Becomes 100% if Pangolier gets his +5% Shield Crash talent, Or there is 5 Meepos), resulting in a near unkillable Pangolier in a short amount of time.
* 
Rolling Thunder disrupts Meepo's initiation or escaping.
* 
Swashbuckle can hit all of Meepo clones.
* 
Lucky Shot can disarm Meepo's clones.
Additional:
* Shield Crash gains its damage reduction bonus from all Meepo clones, and can be used even when rooted, allowing Pangolier to gain a massive amount of damage reduction (even more than 100%).
* With too many clone running around during combat, it is almost impossible for Meepo to avoid Rolling Thunder or Swashbuckle.
* Still, remember that a lone Pangolier can never escape from a ganking Meepo.
Meepo
* Heroes with powerful rooting abilities will disable most of Pangolier's skills, a bonus point if it pierces spell immunity since it will also be able to stop Pangolier during his Rolling Thunder: 
Treant Protector, 
Meepo, Crystal Maiden, 
Dark Willow, 
Underlord, 
Naga Siren
Meepo
* 
Tree Dance and 
Primal Spring allows him to chase a retreating Meepo.
* 
Boundless Strike gains critical strike bonuses and 
Wukong's Command can take down Meepo and his clones very quickly.
Additional:
* Monkey King can gain 
Jingu Mastery stacks on Meepo’s clones from Divided We Stand.
* Tree Dance allows him to sneak up on and gank a lone Meepo clone.
Meepo
* 
Reactive Tazer can lock multiple Meepos in place and prevent them from Poofing.
* 
Proximity Mines, 
Sticky Bomb and 
Blast Off! can deal heavy magic damage to multiple Meepos.
Meepo
* Flaming Lasso is the perfect tool to isolate a single Meepo and focus him.
Pugna
* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:Crystal Maiden, Pugna, 
Skywrath Mage, 
Io, Witch Doctor, etc.
Pugna
* Heroes with no mobility will take some good damage from Sand King's spells: 
Dragon Knight, 
Jakiro, Pugna, 
Earthshaker.
Meepo
* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.
Additional:
* Burrowstrike can stun multiple Meepos, making them vulnerable targets.
* Epicenter and Sand Storm's AoE damage ensures all Meepo clones get damaged, making it hard for Meepo to choose which one to flee as all are taking damage at the same rate.
* Just be aware when using Sand Storm to escape, as Meepo has good AoE damage and disables, which, as explained in the "Bad Against" section, works well against an invisible Sand King.
Pugna
* Pugna's Nether Ward damages Sand King when he channels Epicenter, preventing him from using Blink Dagger afterward.
Meepo
* Low-health, normally mobile carries who rely entirely on raw attack damage are vulnerable to Bane's nukes and disables: 
Anti-Mage, 
Clinkz, 
Drow Ranger, 
Faceless Void, 
Gyrocopter, Juggernaut, Meepo, 
Mirana, 
Monkey King, 
Morphling, Phantom Assassin, 
Phantom Lancer, 
Riki, 
Shadow Fiend, 
Slark, 
Sniper, 
Terrorblade, 
Troll Warlord, 
Weaver.
Pugna
* Spirit Siphon does a lot of magical damage, especially in the early game. This allows her to demolish low health heroes such as 
Zeus, Pugna, especially when combined with her other spells.
Meepo
* Heroes who can stun multiple units at once: Dark Willow, 
Spirit Breaker, 
Slardar, Invoker, and 
Tidehunter.
Pugna
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by 
Lucent Beam if Pugna does not have 
Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and 
Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet their ablities have very high mana costs, Luna does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Additional:
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet have very high mana costs, she does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Meepo
* Illusions and summons are double-edge sword type of matchup for Luna. On one hand, they can tank damage from Eclipse, but on the other hand, she can easily clear them before Eclipse with Moon Glaives. Examples include 
Spectre, 
Shadow Demon, Phantom Lancer, Naga Siren, 
Chaos Knight, Terrorblade) or bring other units into the fight (such as 
Nature's Prophet, 
Lone Druid, 
Chen, 
Enchantress, Meepo and 
Arc Warden).
Meepo
* Even though Moon Glaives can bounce between Meepo and his clones, Meepo can tank Eclipse because of his clones.
* Earthbind takes away Luna's mobility advantage.
* Meepo can shutdown Luna's split-push ability with his global presence.
* For the same reasons, Meepo makes a very powerful ally for Luna when they are in the same team.
Meepo
* 
Tiny's Avalanche affects all Meepos and Toss can send a singular Meepo into death.
Additional:
* Avalanche and Toss prevents Meepo's from using Poof to escape.
* Tiny doesn't need to target the weakest clone while he is affected by Tree Grab.
Meepo
* Besides Lone Druid and Meepo, Doom is potentially good versus every hero since Doom will render any hero helpless for up to 16 seconds. This is particularly true for fragile heroes that heavily rely on mobility to stay alive.
Meepo
* Because only one clone needs to be killed in order to kill Meepo, heroes that excel at singling out enemies can also be a detriment to him, such as Batrider, Beastmaster, Pudge and Clockwerk.
Meepo
* Meepo is quite fragile in the early game and can be easily taken down by Flame Guard's and Searing Chains' damage. Later on, Meepo is very vulnerable to Sleight of Fist's damage due to 
Battle Fury's cleave on multiple Meepos.
Additional:
* 
Sleight of Fist combined with Battle Fury, 
Maelstrom and 
Daedalus will allow Ember Spirit to make a quick work of Meepo if his clones are crowded around each other.
* 
Searing Chains interrupts Meepo's initiating because Meepo's clones do not have spell immunity.
Meepo
* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: 
Earth Spirit, 
Ember Spirit, 
Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots
Meepo
* Light Strike Array can catch Meepo and his clones off-guard if he tries to gank Lina with Earthbind & Poof.
* Laguna Blade can quickly kill Meepo and his clones before they escape with Poof.
Pugna
* Nether Ward will be problematic for heavy nukers and spammers like Skywrath Mage, 
Lina, 
Lion and Invoker, but Pugna must not use Decrepify defensively against them as he will be helping them out more than anything.
Pugna
* Earth Spirit does not fly a small distance on 
Rolling Boulder using 
Stone Remnant, which will be a big problem for Life Drain, since Pugna will stop receiving health from breaking the distance of the ability, which will give the Earth Spirit team a chance to kill Pugna, by the way, this also works well with 
Boulder Smash, which pushes the enemy and can annoy the distance
* Earth Spirit has excellent control with a small recharge on Rolling Boulder and 
Geomagnetic Grip, which can knock down Pugna`s Life Drain, as well as completely turn him off in a fight, because he is very dependent on his abilities
* Magic damage from Earth Spirit's abilities can be disastrous for Decrepify, as it will kill him very quickly, and if Earth Spirit collects 
Ethereal Blade in such a game, it can easily destroy Pugna in one Rolling Boulder hit
* Earth Spirit also turns out to be a strong decision against Nether Ward, because he experiences it with his large amount of health, and if he collects 
Heart of Tarrasque(and 
Bracerin early game)in such a game, he may not feel it at all and calmly control Pugna with his abilities
Additional:
* Earth Spirit does not fly a small distance on Rolling Boulder using Stone Remnant, which will be a big problem for Life Drain, since Pugna will stop receiving health from breaking the distance of the ability, which will give the Earth Spirit team a chance to kill Pugna, by the way, this also works well with Boulder Smash, which pushes the enemy and can annoy the distance
* Earth Spirit has excellent control with a small recharge on Rolling Boulder and Geomagnetic Grip, which can knock down Pugna`s Life Drain, as well as completely turn him off in a fight, because he is very dependent on his abilities
* Magic damage from Earth Spirit's abilities can be disastrous for Decrepify, as it will kill him very quickly, and if Earth Spirit collects Ethereal Blade in such a game, it can easily destroy Pugna in one Rolling Boulder hit
* Earth Spirit also turns out to be a strong decision against Nether Ward, because he experiences it with his large amount of health, and if he collects Heart of Tarrasque(and Bracerin early game)in such a game, he may not feel it at all and calmly control Pugna with his abilities
Meepo
* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots
Meepo
* If Meepo ganks Lion with Poof and Earthbind, he will be an easy target for 
Earth Spike & AoE 
Hex from his level 25 talent.
Pugna
* Nether Ward will be problematic for heavy nukers and spammers like Skywrath Mage, Lina, Lion and Invoker, but Pugna must not use Decrepify defensively against them as he will be helping them out more than anything.
Meepo
* Meepo is vulnerable to area damage and disables from Magnus himself as well as his team through Empower.
Pugna
* Any hero who can counter-initiate in anticipation without getting caught in Reverse Polarity: 
Sven, 
Omniknight, Enigma, 
Luna, Naga Siren, 
Mars, Jakiro, 
Venomancer, Elder Titan, Faceless Void, 
Rubick, 
Keeper of the Light, Pugna, Invoker, Spectre, 
Alchemist, Treant Protector, Lina, 
Oracle, Zeus, 
Shadow Shaman, 
Phoenix, 
Razor, 
Huskar, Batrider, 
Kunkka, Tidehunter, 
Wraith King, Sand King, 
Medusa, 
Dawnbreaker.
Meepo
* Aggressively Poofing and Earthbinding is not going to end well against Venomancer, as he will be an easy target for 
Noxious Plague.
* Venomancer's constant slows greatly reduce Meepo's mobility.
Pugna
* Any hero that can outrange Plague Ward can neutralize them without putting themselves at risk of receiving Poison Sting: Arc Warden, Chen, Clinkz, Drow Ranger, Lina, Mirana, Nature's Prophet, Pugna and Sniper.
* Special mention to heroes that outrange Plague Ward after obtaining talents that increase attack range.
Pugna
* Even though Pugna's low HP means that he can be quickly burst down, his Nether Ward heavily punishes casters whose spells cost a lot of mana, like Zeus. Casting 4 of his active spells, including Nimbus, close to an enhanced level 4 Nether Ward, can make the ward deal up to 1750 magical damage.
* Decrepify can further increase the damage dealt by Nether Ward upon Zeus. However, if used on Pugna himself or on one of his allies, it will amplify the damage done by Zeus' abilities.
Meepo
* Thundergod's Wrath strikes only the first Meepo.
* Zeus has low mobilty so consecutive Earthbinds are easy to hit and he'll quickly die from Poofs.
Pugna
* Nether Ward causes Death Pulse to actually damage Necrophos rather than heal him. Meanwhile, Reaper Scythe's gigantic mana cost while Necrophos is near the Nether Ward can often instantly kill him.
* Nether Blast and Life Drain both make quick work of Necrophos's small healthpool, especially during Ghost Shroud. The latter also makes him an unappealing target for Reaper's Scythe, and can often force Necrophos to use it defensively as he has no other means of interrupting his channeling.
Meepo
* Necrophos struggles at clearing away durable illusions or summons. Meepo can overwhelm Necrophos with his many duplicates, especially in the later stages of the game, and his Earthbind will prevent Necrophos from getting away, even if he casts Ghost Shroud.
* Meepo's high burst damage from Poof can make it difficult for to Necrophos to stay alive, and as Necrophos excels in extended fights, he will not be able to do as much damage as he intends to.
Pugna
* All of Pugna's abilities are active, making Demonic Purge break from Aghanim's Scepter useless.
* Nether Ward punishes Shadow Demon's constant mana usage from spamming spells, especially Shadow Poison.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Nether Blast for the enemy.
* Life Drain can be used to heal Pugna or an ally to save them from Shadow Demon's abilities.
* However, it can be cancelled by Disruption unless Pugna buys defensive items.
Meepo
* Poof will destroy Shadow Demon's illusions created by 
Disruption and quickly escapes from 
Shadow Poison & 
Demonic Purge.
Pugna
* Decrepify on either hero stops Legion Commander from completing a Duel, and dissuades her from initiating Duels on ethereal allies.
* Life Drain can help Pugna's teammates win a fight, either by killing Legion Commander or replenishing her target's health.
Additional:
* Decrepify prevents Legion Commander from attacking allies during 
Duel, regardless if it's used on her or on the ally .
* Pugna can easily cast Decrepify, Nether Blast and Life Drain on Legion during the 4/4.75/5.5/8 seconds of duel
Meepo
* When Legion Commander uses Duel on one Meepo, he can use his other Meepos to kill her. If he wasn't dueled, he can help the teammate who was duelled to give the teammate the damage instead of Legion Commander.
* However, if Legion Commander picked up an Aghanim's Scepter and she duels one Meepo, that might be the end of Meepo if Legion managed to gather enough damage from previous duels.
Pugna
* Arc Warden can't use Magnetic Field to stall the damage of Nether Blast on towers, but he can buy 
Aghanim's Shard to diminish its damage.
* Arc Warden has no innate disables to stop Life Drain and Decrepify
* The short cooldown of both Life Drain and Decrepify also means Pugna can deal with Arc Warden and Arc Warden's clone simultaneously most of the time
* A good Pugna looks to end the match early while Arc Warden, a very item reliant hero, thrives in longer matches.
Meepo
* Flux is severely impaired against Meepo because of Divided We Stand.
* Meepo's farming speed and early powerspikes allows him to pressure Arc Warden before he is capable of fighting effectively.
* Without Black King Bar, Earthbind and Poof can finish Arc Warden quickly before he has time to do much.
Pugna
* Pugna's Decrepify can render Templar Assassin's physical attacks useless.
* Pugna can also cast Life Drain on Templar Assassin, burning her Refraction instances.
* On the other hand, Pugna generally has low health and armor. Use this to your advantage.
Meepo
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, 
Lycan, Enigma, Shadow Shaman
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her 
Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, 
Queen of Pain, Shadow Shaman (
Shackles), Jakiro, Pugna, 
Doom
Pugna
* Nether Blast is one of the best tower pushing abilities in the game, with a low cooldown. A competent Pugna will (at the very least) destroy tier 2 towers and make space for his team before Spectre can finally come online.
* Spectre's spells, while not spammable, have a fairly high mana cost, so Nether Ward can be fairly damaging to Spectre early game. The mana degen will also dampen Spectre's early game power significantly.
* Once Pugna gets Aghanim's Scepter, he can spam Life Drain on any illusion Spectre summons, whether it'd be from 
Haunt, 
Manta Style, or some other means.
* In addition, Pugna can disable Spectre's 
Desolate ability (although its damage is pure, it requires physical attacks) with his Decrepify ability, leaving Spectre only with 
Spectral Dagger.
Meepo
* Spectre's Haunt with Radiance may be useful for countering Meepo but if Meepo finds the real one, Spectral Dagger is useless. Non-Black King Bar heroes like her will suffer from all of Meepo's abilities. Meepo is also a very large counter as Spectre takes a long time to come online, normally farming in the jungle or in lane, which makes her an easy target for Meepo ganks.
Additional:
* Poof combined with Earthbind can be used to easily lockdown and burst Spectre down.
* As Meepo's playstyle is often to come online early to mid game and take over the whole game, Meepo will often be much further ahead of Spectre in farming.
* Meepo's global map presence allows him to effectively hunt for Spectre and disrupt her farm.
* Spectre has no strong AOE abilities or way to control or lock down Meepo.
Pugna
* Pugna easily copes on the line with the Keeper of the Light push with his Nether Blast, and in addition to Nether Ward, the Keeper of the Light is not able to throw 
Illuminate on creeps for a long time, so Pugna earns more gold and a level on the line
Additional:
* Pugna easily copes on the line with the Keeper of the Light push with his Nether Blast, and in addition to Nether Ward, the Keeper of the Light is not able to throw Illuminate on creeps for a long time, so Pugna earns more gold and a level on the line
Meepo
* Heroes that can jump and kill him: Meepo, Clinkz, 
Templar Assassin
Pugna
* Nether Blast will still hit Slark even if he is hidden during Shadow Dance.
* Even though Pugna can rarely target Slark directly with Decrepify, he can still use it defensively on an ally to prevent Slark from getting stacks.
* Despite being somewhat easy to break with Pounce, Pugna can damage Slark and provide vision over him with Life Drain.
Meepo
* Slark's Dark Pact and Pounce can deny only one Earthbind and Poof can penetrate Shadow Dance if he doesn't build Black King Bar.
Additional:
* Earthbind and Poof will still hit Slark in Shadow Dance.
* Dark Pact can only remove one Earthbind.
* 
Ransack will still affect Slark, even if he has a Black King Bar.
Pugna
* Decrepify prevents 
Omnislash damage, until Juggernaut gets a Nullifier.
* Without a disable, Pugna's high movement speed makes it harder to chase him with 
Blade Fury.
* Juggernaut has low mana and his skills cost large amount of mana. Nether Ward will hurt him more and even worse, the damage from the ward is inflicted before the Spell immunity provided by Blade Fury.
Additional:
* Decrepify is the perfect tool against Omnislash until he gets a Nullifier, and even then he will probably waste a couple of slashes before he uses it.
* Without an extra disable, Pugna's high movement speed makes it impossible to chase him with Blade Fury.
* Unlike some other carries like Slark or Phantom Assassin, Juggernaut's spells cost a hefty amount of mana and he will seriously get hurt by Nether Ward. Don't forget the damage from the ward is inflicted before the spell immunity is provided by Blade Fury.
Meepo
* Juggernaut's Omnislash is meaningless for Meepo who can share the damage across clones to save other allies.
Pugna
* Due to the high mana cost of his spells and the low cool down of them, Nether Ward can seriously damage Skywrath Mage if he isn't careful.
* Skywrath Mage's fragility makes him very susceptible to Pugna's high burst damage.
Additional:
* Nether Ward will make Skywrath Mage next to useless in fights, as his low hp pool will not allow him to sustain through the damage of the ward should he choose to cast spells. Be wary though that Skywrath's huge burst will make very quick work of Pugna's low hp should the ward be destroyed, and Decrepify won't help Pugna at all.
Meepo
* Skywrath Mage's abilities are single targeted and he can't use Mystic Flare to its fullest potential, since all Meepos spread the damage between them. He also has no disables to prevent Meepo from Poofing to another one (unless he can get 
Ancient Seal off first).
Pugna
* Nether Ward discourages Tinker from using abilities and items due to its high damage against heavy mana usage.
Meepo
* 
Tinker who can't fight multiple heroes will suffer greatly against Ransack and Earthbind.
Meepo
* Enchantress's 
Untouchable slows down Meepos attacks and 
Impetus can deal heavy pure damage to a single Meepo, however once Meepo has closed the gap she is an easy target for Poof.
Pugna
* Amazingly, Enchantress has even lower health than Pugna. Though she does pack quite a punch through Impetus, she can't use it if she is under Decrepify.
* Pugna's Magical DPS is way greater than the heal from 
Nature's Attendants, which will also harm her quite a bit if she's next to Nether Ward.
Meepo
* Meepo can quickly kill Enchantress with a Poof combo, rendering Untouchable useless.
Pugna
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during 
Mortimer Kisses and dodge the projectiles easily due to their slow speed.
* Heroes with mobility spells (such as Queen of Pain's 
Blink and Clockwerk with Hookshot) can easily avoid 
Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
Meepo
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with Hookshot) can easily avoid Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
Pugna
* Heroes who are reliant on physical damage will be nullified by Decrepify: Riki, Wraith King, Juggernaut.
Meepo
* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots
Additional:
* Root is a deadly threat to Riki, disabling both 
Blink Strike and 
Tricks of the Trade while making him fully revealed, making Earthbind a good ability against him.
* 
Smoke Screen may not be able to silence all the Meepo clones.
* Riki has no true area damage, as Tricks of the Trade's damage is distributed between all Meepo clones, so he cannot effectively fight Meepo or deal with his strong ability to push unless Riki has Battle Fury.
Pugna
* Heroes that can apply early pressure before Phantom Assassin has farm are massive threats: 
Axe, 
Viper, Meepo, Jakiro, Pugna, Slark, Venomancer etc.
Meepo
* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots
Pugna
* Heroes who are reliant on physical damage will be nullified by Decrepify: Riki, Wraith King, Juggernaut.
Meepo
* Meepo has a better advantage in farm with Divided We Stand, as well as having a higher attack speed due to his tendency to build items that give attributes. In addition, Wraithfire Blast stuns only one target, and choosing to engage one Meepo will most certainly mean engaging them all.
Pugna
* Heroes that can punish aggressive heroes, such as: 
Leshrac, Shadow Demon, Pugna, 
Death Prophet.
Meepo
* 
Night Stalker's most skills are single targeted which allows other Meepos to Poof, Earthbind and kill him.
Meepo
* Earthbind disables Waveform, effectively keeping Morphling in place for an extended period of time, allowing Meepo to deal considerable damage with Poof.
Pugna
* Nether Blast can deal high damage to Chen and clear waves of his creeps.
* Decrepify can be used to waste the duration of 
Penitence.
* Nether Ward can discourage Chen from using Penitence, 
Holy Persuasion and 
Hand of God due to their fairly high mana costs.
* Life Drain can often kill Chen or any of his allies before he can save them with Hand of God thanks to it's high damage and low cooldown.
Pugna
* Pugna can turn out to be an effective hero against Dazzle due to the fact that he does not allow him to extend his 
Poison Touch with his Decrepify, which is why Dazzle cannot keep the enemy under prolonged deceleration.
* Pugna has a very strong ability against casters with a small health reserve - Nether Ward, which is why heroes like Dazzle will not be able to constantly throw their Poison Touch 
Bad Juju and 
Shadow Wave at enemies under the action of Nether Ward or will be forced to take a lot of damage
Additional:
* Pugna can turn out to be an effective hero against Dazzle due to the fact that he does not allow him to extend his Poison Touch with his Decrepify, which is why Dazzle cannot keep the enemy under prolonged deceleration.
* Pugna has a very strong ability against casters with a small health reserve - Nether Ward, which is why heroes like Dazzle will not be able to constantly throw their Poison Touch Bad Juju and Shadow Wave at enemies under the action of Nether Ward or will be forced to take a lot of damage
Pugna
* Decrepify prevents Faceless Void from attacking trapped allies inside 
Chronosphere, wasting a large portion of its duration if Faceless Void can't dispel it.
Meepo
* Chain of Earthbinds prevents her from using Blink, allowing Meepo to quickly kill her with Poof and attacks.
* Meepo tends to buy items with attributes, mitigating Queen of Pain's magical burst.
Additional:
* Meepo is the hard counter for Queen of Pain - chaining Earthbinds prevents her from using Blink for a long time, and without any other escape options, Queen of Pain cannot survive several Poofs and attacks.
* Meepo tends to build items with attributes, mitigating Queen of Pain's magical burst.
Meepo
* Earthbind can prevent Phoenix from using 
Icarus Dive, the only escaping mechanism of this hero.
* Heavy burst damage from Poof can easily kill Phoenix even when it slows down all the Meepos with 
Fire Spirits.
* Meepo's clones destroy the Phoenix Sun from 
Supernova in no time, even when they are slowed down by Fire Spirits.
* Meepo's naturally high magic resistance gives Phoenix a hard time with bursting him down. He can even turn the tide if Icarus Dive is on cooldown.
Additional:
* Meepo is unlike any other multi-unit enemy Phoenix may face in the battlefield. Unlike illusion-based heroes like Phantom Lancer or Chaos Knight, Meepo's clones are not illusions, meaning they can deal full damage to the Phoenix Sun if all four (or five) are present.
Pugna
* Nether Ward can do a ton of damage to Disruptor because of his high mana costs.
* Life Drain can be used to heal an ally trapped by Static Storm-Kinetic Field combo (if Pugna is not a target).
Meepo
* Ogre Magi has single-targeted magical-only damage and disables and is less effective against Meepo's clones.
Meepo
* Earthbind prevents Broodmother from escaping Meepo's attacks.
* Poof will quickly clear any nearby spiders.
* Broodmother often picks off single target heroes. With Meepo's Divided We Stand, it gets a lot harder once every Meepo Poofs in.
Meepo
* With all 5 Meepos available, all of Shaman's wards will be disposed of very quickly.
* All of Shaman's disables are based around single target control, and he can at most only disable two Meepos, allowing the rest to easily lay waste to him, be it during the channel duration of Shackles or by using Earthbind.
Pugna
* As Terrorblade's damage output comes mainly from direct attacks, he will struggle greatly against heroes who have abilities that give evasion, trigger on attack or which can disarm an enemy hero: 
Centaur Warrunner, 
Hoodwink, Huskar, Invoker, Leshrac with 
Nihilism from Aghanim's Scepter, 
Lifestealer with Aghanim's Scepter upgraded 
Infest, 
Pangolier, Phantom Assassin, Pugna, 
Techies, 
Windranger etc.
Meepo
* Mirana cannot use Leap while rooted by Earthbind and her Moonlight Shadow is countered by Meepo's true sight that is provided by Earthbind.
Additional:
* Earthbind prevents Mirana from Leaping or going invisible with Moonlight Shadow. She can be easily killed by Poof and Ransack while disabled.
* Landing a Sacred Arrow on Meepo does not render him helpless, as all of the other Meepos can still fight back.
Meepo
* Naga Siren's Song of the Siren may be useful but Poof will destroy all of her illusions.
Meepo
* Nature's Prophet is heavily countered by Meepo, not only Meepo can kill the treants with a single Poof, but he can also stop Nature's Prophet from using 
Teleportation, and can gain vision inside 
Sprout.
Additional:
* Meepo can net Nature's Prophet's treants with Earthbind and then Poof them, putting an end to his pushing.
* Skilled Meepos can rival and even exceed Nature's Prophet's global presence by combining Poof with 
Boots of Travel, meaning that he can not only stop his push, but also can kill him if he is not careful.
Pugna
* Pugna's Decrepify prevents the target from taking physical damage or doing damage, which poses a huge problem for Lycan, as he mainly deals physical damage.
Pugna
* Pugna is a very fragile hero who can easily get caught and killed by Storm Spirit's long range initiation.
* This is especially true if he has 
Orchid Malevolence or 
Scythe of Vyse.
* Pugna has no disables that can prevent Storm Spirit from escaping.
* Even though 
Ball Lightning requires high amount of mana, Nether Ward is ineffective since Storm Spirit is invulnerable while using it.
* Storm Spirit's other abilities cost very insignificant amount of mana for Nether Ward to be effective.
Pugna
* Heroes with mana burn: 
Nyx Assassin, Invoker, 
Outworld Destroyer, Pugna, Lion
Meepo
* Earthbind, like any root, inhibits usage of Ball Lightning, eliminating Storm Spirit's mobility.
Meepo
* Heroes with high mobility can be prevented from using it to their advantage with Earthbind, even if they pack a dangerous arsenal: Earth Spirit, Ember Spirit, Storm Spirit, Nature's Prophet, Phantom Assassin, Riki, Anti-Mage, Weaver.
* See items and abilities disabled by roots
Pugna
* Pugna's Decrepify makes sure that either Alchemist is unable to hit anyone while also being slowed and susceptible to magical damage, or can protect an ally from physical attacks. Besides, Pugna can push early on, when Alchemist is not strong enough to repel it, so by the time Alchemist comes online, he might be forced to sit in base.
Meepo
* Meepo can quickly destroy Tombstone thanks to Divided We Stand.
Pugna
* Any heroes with high intelligence, such as Invoker and Pugna.
Pugna
* Pugna: Decrepify prevent the Spirit bear from attacking or protect allies from it.
Meepo
* Heroes that can overwhelm Visage by sheer number like Chaos Knight, Meepo, Terrorblade and Phantom Lancer.
Meepo
* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.
Pugna
* Nether Ward on its own can greatly hinder Invoker from casting many of his abilities, at least until he gets a significant amount of HP or is under the protection of spell immunity from Black King Bar
* Life Drain provides True sight, revealing Invoker through Ghost Walk, and forcing him or his allies to use an ability or item to interrupt its channeling
* Outside of Nether Ward's range, Invoker shall have the advantage, as Invoker has Tornado to purge Pugna's Decrepify when it is used defensively, Tornado or Cold Snap to prevent Pugna from channeling Life Drain
* A poorly used Decrepify on Pugna's allies means Invoker's abilities can be used to deal more damage to them.
Additional:
* Because Invoker relies on casting a large amount of spells to contribute to fights, Nether Ward can force him to not cast anything at all or take a large amount of damage to cast spells.
Meepo
* Heroes who can stun multiple units at once: Dark Willow, Spirit Breaker, Slardar, Invoker, and Tidehunter.
Meepo
* Slardar does not do well against multiple targets, as his only way to damage multiple targets is Slithereen Crush.
* Meepo's Earthbind will root Slardar, making him unable to chase/escape for the time being. Also, Poof's low cooldown and high damage can burst Slardar down rather quickly.
Meepo
* Shadow Fiend's Requiem of Souls not only slow all Meepos, but it can also kill the weakest Meepo instantly if the ultimate is released at the right position and time.
Additional:
* Shadow Fiend can easily focus down and kill one of the Meepos.
* The amount of damage from Shadow Fiend's AoE spells makes Meepo vulnerable in every aspect.
Pugna
* Decrepify prevents Shadow Fiend from attacking for its duration, potentially preventing him from getting a kill.
* Nether Ward can do heavy damage to Shadow Fiend if he tries to cast his 
Requiem of Souls and his 
Shadowraze.
Additional:
* Decrepify prevents Shadow Fiend from attacking for its duration, potentially preventing him from getting a kill.
* Nether Ward can do heavy damage to Shadow Fiend if he tries to cast his Requiem of Souls or spam Shadowraze.
Meepo
* Troll Warlord can root and deal a lot of damage to a single Meepo while lifestealing through the assault from the other Meepos. Meepo needs expensive items like Ethereal Blade or 
Heaven's Halberd to be able to fight him.
Pugna
* Troll Warlord can't switch targets at will, in order to build 
Fervor stacks, which makes it easy to use Decrepify in order to save allies
* During 
Battle Trance, Pugna can easily use Nether Blast, Decrepify and Life Drain on him
Meepo
* Heroes who can stun multiple units at once: Dark Willow, Spirit Breaker, Slardar, Invoker, and Tidehunter.
Meepo
* Earthbind's root prevents/interrupts Charge of Darkness.
* As a single-target focused hero without much damage output, Spirit Breaker is ineffective in general against Meepo.
Meepo
* 
Void Spirit can dodge Earthbind with 
Dissimilate and 
Astral Step, giving him a good chance to escape. If he gets caught anyways, 
Resonant Pulse allows him to retaliate.
Meepo
* Meepo's Earthbind can easily lockdown Void Spirit.
* Meepo and his clones can easily burst Void Spirit's Resonant Pulse.
Meepo
* Heroes with powerful area-of-effect disables can initiate on Meepo and his clones and shut him down, such as Enigma, Invoker, Magnus, Puck, and Sand King.
Pugna
* Enigma's abilities have a huge mana cost, meaning that Nether Ward will deal a lot of damage to Enigma.
* Pugna can heal allies trapped inside Black Hole thanks to Life Drain, Pugna can also damage multiple of Enigma's allies around him with Life Drain when he casts it on Aghanim's Shard upgraded Nether Ward during teamfight.
* Nether Blast can easily kill Eidolons, especially when Enigma is pushing.
* Even though Pugna cannot cancel 
Black Hole on his own, smart Pugna can buy Orchid Malevolence to stop Enigma from channeling Black Hole and make him more vulnerable to counter-attacks with Decrepify and Life Drain.
Additional:
* Enigma's abilities have a huge mana cost, meaning that Nether Ward will deal a lot of damage to Enigma.
* Pugna can heal allies trapped inside Black Hole thanks to Life Drain.
* Nether Blast can easily kill Eidolons, especially when Enigma is pushing.
Meepo
* Melee heroes who rely on summons, illusions, or clones will trigger Counter Helix more often, thus taking more damage: Meepo, Lycan, Phantom Lancer
Additional:
* The combination of 
Counter Helix and 
Berserker's Call can disable multiple Meepos and deal heavy area damage.
* Axe's natural high survivability makes it difficult to burst him down with Poof or chip away at his health with Ransack.
Pugna
* Decrepify can be used on allies to prevent them from attacking Axe and triggering Counter Helix during Berserker's Call. He can also cast it on Axe to prevent anyone from attacking him.
* Life Drain can be used to heal himself or allies caught in Berserker's Call, preventing them from dropping low enough for Axe to kill them with Culling Blade.
Pugna
* Phantom Lancer creates way too many illusions for Pugna's Life Drain to destroy, overwhelming him easily.
* 
Doppelganger can dodge Nether Blast or dispel Decrepify.
* Diffusal Blade is a common item for Phantom Lancer to burn Pugna's large mana pool and deals a large amount of damage in the process.
Additional:
* Though Life Drain instantly destroys illusions, Phantom Lancer creates way too many for Pugna to handle.
* A good Phantom Lancer will also dodge your Nether Blast with Doppelganger.
* Phantom Lancer is the most natural Diffusal Blade carrier to burn Pugna's very large pool of mana away and deal a large amount of damage in the process.
Meepo
* Poof will destroy Phantom Lancer's illusions within a short time.
* Earthbind prevents Phantom Lancer from using Doppelganger.
Additional:
* Poof from multiple Meepos will destroy illusions quickly.
* Earthbind's area root can catch Phantom Lancer in a group of illusions and prevent him from using Doppelganger for a long time.
* Meepo aims to end the game as early as possible, while Phantom Lancer is a lategame hero.
* This also means that, in the late game, Meepo stands no chance against Phantom Lancer.
Meepo
* Heroes that have doubles or clones such as Arc Warden, Meepo or Lone Druid are vulnerable to Muerta's 
Gunslinger.
Pugna
* Heroes that commonly attack ethereal units will not have any problems against Muerta's Pierce The Veil: Tinker, Jakiro, Lina, Luna, Pugna or 
Ogre Magi, Enigma, Batrider, Techies, 
Broodmother, Dawnbreaker, Shadow Shaman, Bane, Tinker, Venomancer, Arc Warden.
Meepo
* 
Bulwark blocks the attack from Meepo and his clones.
* 
Spear of Mars & 
God's Rebuke prevents Meepo and his clones from initiation or escaping.
Pugna
* Nether Blast, Decrepify and Life Drain deal high magical damage and bypasses Bulwark.
* Nether Ward reduces the amount of abilities Mars can use during fights and forces Mars to be careful about the heavy mana cost of Arena Of Blood.
* Pugna is one of few heroes that can contest Mars' ability to push and defend towers early on.
Pugna
* Pugna only deals magical damage, which Anti-Mage is exceptionally resistant due to Counterspell.
* Anti-Mage can dispel Decrepify with Manta Style.
* Pugna has a very large mana pool. This allows Anti-Mage to constantly deal bonus damage to Pugna with Mana Break and devastate Pugna's entire team with Mana Void.
Additional:
* Since Pugna relies on his teammates for protection, it is fairly common for Anti-Mage to get multiple kills with a single use of his 
Mana Void on Pugna if he's missing a considerable portion of his mana.
* Pugna's massive mana pool will result in Anti-Mage's 
Mana Break almost always dealing the bonus damage from the mana burn.
* 
Counterspell negates a large amount of Pugna's damage, as most of Pugna's damage comes from his spells.
* 
Blink can be used to get out of a bad situation, and Pugna has no way to prevent him from casting it.
Meepo
* Multiple Earthbinds allows Meepo to lock down Anti-Mage almost indefinitely.
* Meepo's clones can only use their mana for Poof, keeping their mana pool nearly full and thus making them a bad target for a Mana Void.
Additional:
* Earthbind can prevent Anti-Mage from using Blink, allowing Meepo to kill him with attacks and Ransack.
Meepo
* Because multiple Meepos tend to clump up, they present an easy target for Timbersaw's many area abilities.
* Although be careful since Timbersaw cannot use 
Timber Chain to escape if rooted from Earthbind.
Pugna
* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw.
* Decrepify can further increase all the magical damage done to Timbersaw, bypassing the enhanced physical resistance he can get from 
Reactive Armor.
Additional:
* Nether Ward can punish Timbersaw, as Timbersaw is a spell-caster with low cooldowns. Furthermore, Timbersaw usually appears in the midst of battle, placing himself in range of Nether Ward's Mana Flares.
* Timbersaw has no stuns or silences to stop Life Drain. Since all of Pugna's Spells are magical, the damage can be devastating to Timbersaw, especially when combined with Decrepify.
Meepo
* Pulse Nova deals an insane amount of damage in an area around him, which can quickly wear down Meepo clones.
* Leshrac can catch multiple Meepos in Split Earth and follow up with the rest of his area damage spells making Meepo unable to get close to Leshrac.
* Diabolic Edict is a strong ability that can wear down a lone Meepo clone quickly.
Pugna
* Nether Ward punishes Leshrac's constant mana usage from spamming spells.
* Leshrac needs to be in the thick of the fight to deal damage, and so cannot escape from Nether Blast nor Life Drain easily.
Additional:
* Leshrac needs to be close to target in order to do damage, Pugna can outrun Leshrac with ease due to his superior movement speed.
* 
Split Earth can also be hard to land on Pugna for the same reason.
* Leshrac uses huge amounts of mana to do damage, Nether Ward forces him to either not contribute in a fight or kill himself in the process.
Meepo
* 
Viper Strike prevents the lifesteal from Ransack.
* Meepo and his clones have a lack of magic resistance, so they're vulnerable to 
Poison Attack & Viper Strike directed onto one clone.
Pugna
* Pugna's Decrepify allows him to save allies from being ganked by Viper, since Viper mostly relies on direct attacks in order to deal damage.
* Nether Ward can discourage Viper from spamming his abilities.
* Viper's damage over time is not enough to kill Pugna as he will have more than enough time to save himself (or his allies) with Life Drain and Viper has no solutions to cancel it.
* Pugna has no passive abilities, which renders 
Nethertoxin nearly useless.
Meepo
* Lifestealer is not affected by Earthbind or Poof during 
Rage, making him a difficult target to work around.
Meepo
* Lifestealer's Rage and Open wounds become useless when Meepo has 4 or more clones, as Ransack will heal Meepo too quickly for Lifestealer to take down.
Meepo
* 
Great Cleave and 
God's Strength can take down Meepo and his clones very quickly.
* The lack of spell immunity for Meepo's clones makes them vulnerable to 
Storm Hammer.
Additional:
* Great Cleave will devastate Meepo's clones. Against a closely packed group, Sven does not even need to target the clone with the lowest health.
Pugna
* Pugna can save allies with both healing or by making them ethereal but needs to be careful of Sven's Aghanim's Scepter purge.
Meepo
* 
Winter's Curse in late game is pretty much the end for Meepo or any of his nearby allies. Natural counter for Winter's Curse like 
Linken's Sphere or 
Lotus Orb is meaningless to her if she can land it on one of Meepo's clones.
Additional:
* Meepo's clones usually gets grouped in teamfight making any of them ideal target for Winter's Curse, forcing Meepo to literally kill himself. Also, unlike other heroes he cannot protect himself with Linken's Sphere.
* While Meepo's clones are grouped up, Splinter Blast will hit almost every clone, slowing Meepo and making him easier to fight.
Pugna
* Cold Embrace is a death sentence against Pugna, since its the perfect setup for all his abilities, especially Life Drain.
* Decrepify can be cast to save the ally under Winter's Curse effect, wasting most of its duration.
* Winter Wyvern's abilities require a lot of mana, allowing Nether Ward to deal lots of damage.
Meepo
* Heroes without blink mechanisms or spell immunity will have a hard time positioning against 
Pit of Malice: Sven, Tiny, Wraith King, Dragon Knight, Meepo, Doom, 
Bounty Hunter, 
Dark Seer, 
Undying, Alchemist, 
Legion Commander.
Pugna
* Heroes with magical or pure damage output will not have any problems against Atrophy Aura at all: Luna, Lina, Jakiro, Pugna, Bane, 
Snapfire, 
Muerta, Nyx Assassin, Enigma, Tinker, Witch Doctor, Zeus, Crystal Maiden.
Pugna
* Both Jakiro's Ice Path and Liquid Frost can be used to cancel
Life Drain from either Jakiro or an ally.
Decrepify only makes Pugna even more vulnerable to Jakiro's magical damage, And it has no adverse effects on Jakiro himself.
Aghanim's Scepter upgraded 
Macropyre can deal pure damage-over-time and pierce debuff immunity, which can discourage Pugna from even trying to use 
Life Drain.
Nether Ward can do some considerable damage to Jakiro due to high mana costs on his abilities.
*
*
* Bear in mind, however, that
Meepo
* All of Jakiro's skills are Area of Effect, which can easily affect all Meepos in a targeted area.