* Both Jakiro's Ice Path and Liquid Frost can be used to cancel Life Drain from either yourself or an ally.
* Decrepify only makes Pugna even more vulnerable to Jakiro's magical damage, And it has no adverse effects on Jakiro himself.
* Aghanim's Scepter upgraded Macropyre can deal pure damage-over-time and pierce spell immunity, which can discourage Pugna from initiating with Life Drain.
* Just be warned that Nether Ward can do some considerable damage to Jakiro due to high mana costs on his abilities.

* Jakiro's skill arsenal can ruin Nature's Prophet's gameplay: Dual Breath and Liquid Fire can clear treants from Nature's Call while simultaneously slowing Nature's Prophet, Ice Path can disrupt Nature's Prophet's escaping attempt with Teleportation, and Macropyre can easily clear treants from Nature's Call.
Additional:
* Jakiro's Macropyre can help him to escape from Sprout and quickly clears Treants.
* Jakiro can disrupt Nature's Prophet's escape attempt with Sprout and Teleportation by using Ice Path.

* Pugna's squishiness and lack of mobility make him easy prey for a Hookshot initiation.
* Clockwerk's high health, low mana costs, and lack of reliance on Blink Dagger make Nether Ward ineffective.
* Battery Assault shuts down Aghanim's Scepter upgraded Life Drain, as the repeated ministuns prevent Pugna from channeling for an extended length of time.
Additional:
* Clockwerk loves to Hookshot low health, immobile targets like Pugna.
* Pugna's Life Drain gets immediately and repeatedly (if an Aghanim's Scepter was purchased) cancelled due to Battery Assault, especially if Pugna is trapped inside Power Cogs.
* Clockwerk also loves to build Blade Mail, which will deal more damage to Pugna than Clockwerk due to Pugna's low health pool.
* Finally, both Hookshot and Rocket Flare can allow him to finish off Pugna out of range of his Nether Ward.

* Clockwerk's long range initiation and catch makes it incredibly difficult for Nature's Prophet to split push and show on the map alone.
* Rocket Flare can be used to scout Nature's Prophet if he is hiding in the forest, and can provide vision inside of Sprout.

* Spirit Siphon does a lot of magical damage, especially in the early game. This allows her to demolish low health heroes such as Zeus, Pugna, especially when combined with her other spells.

* Crypt Swarm can quickly kill any Treants. Silence also prevents him from using Teleportation to escape or Sprout to lock you down.
Additional:
* Crypt Swarm helps clear waves of Treants.
* Silence prevents Nature's Prophet from using Sprout or Teleportation.
* Exorcism kills Treants with ease.

* Pugna only deals magical damage, which Anti-Mage is exceptionally resistant due to Counterspell.
* Anti-Mage can dispel Decrepify with Manta Style.
* Pugna has a very large mana pool. This allows Anti-Mage to constantly deal bonus damage to Pugna with Mana Break and devastate Pugna's entire team with Mana Void.
Additional:
* Since Pugna relies on his teammates for protection, it is fairly common for Anti-Mage to get multiple kills with a single use of his Mana Void on Pugna if he's missing a considerable portion of his mana.
* Pugna's massive mana pool will result in Anti-Mage's Mana Break almost always dealing the bonus damage from the mana burn.
* Counterspell negates a large amount of Pugna's damage, as most of Pugna's damage comes from his spells.
* Blink can be used to get out of a bad situation, and Pugna has no way to prevent him from casting it.

* Anti-Mage's high mobility from Blink and tendency to build Battle Fury makes him strong against split-pushing heroes: Nature's Prophet, Tinker, and Arc Warden.

* Heroes with channeled abilities can be interrupted by a long-range Fissure: Crystal Maiden, Witch Doctor, Bane, Pugna, Pudge.

* Treants increase Echo Slam's damage.
* Earthshaker's AoE stuns can hit Nature's Prophet through Sprout, without having direct line of sight, in order to interrupt Teleportation.
Additional:
* Echo Slam can do a lot of damage to Nature's Prophet and his teammates if they stand close to his Treants.

* Nether Blast's animation makes it easy to time Spiked Carapace for a stun.
* Pugna has the largest intelligence gain in the game, making him a prime target for Mana Burn.
* Pugna needs to channel Life Drain, making him easy to hit with Impale.
Additional:
* Due to Pugna's incredible intelligence growth and terrible strength growth, Nyx should always be able to take you out with his combo, with or without an added Dagon. Mana Burn will deal a large amount of damage in particular, especially in the late game.
* Spiked Carapace is also a great tool versus Pugna. A good player will wait for you in Vendetta until you farm a creep wave with Nether Blast and reflect it back at you as their initiation and setup for Impale.

* Heroes with invisibility: (Riki, Clinkz, Nyx Assassin.

* Trample and Pulverize can be used to cancel Life Drain very quickly.
* Pugna has a very low strength gain and as a support does not have much gold to buy health items, making him vulnerable to Primal Beast's onslaught of magical damage.
* Ironically, Decrepify actually just increases Primal Beast's damage on the targeted ally if Trample is activated. However, it can be used to slow him down and prevent any further Trample damage.

* Heroes with unorthodox escapes will struggle against Primal Beast, such as Nature's Prophet, Tinker, and Templar Assassin.

* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet their ablities have very high mana costs, Luna does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.
Additional:
* Luna can deal constant damage to Pugna through the low-cooldown Lucent Beam and her right clicks.
* Life Drain will be always canceled by Lucent Beam if Pugna does not have Black King Bar.
* Decrepify can be suicide against Luna due to Lucent Beam and Eclipse.
* Nether Ward is rather weak against Luna because unlike other heroes who rely on magical damage to damage or kill enemies, yet have very high mana costs, she does not have abilities that cost a lot of mana and Luna mostly uses her abilities to initiate a teamfight or to finish off fleeing enemy heroes.
* Luna is a common Black King Bar carrier, which allows her to protect herself against Pugna's only-magical damage output.

* Moon Glaives and Lunar Blessing help Luna quickly kill Nature's Prophet's treants.
* Luna can easily cancel Teleportation with her Lucent Beam.
* Even though Nature's Prophet can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.
Additional:
* Moon Glaives and Lunar Blessing help Luna quickly kill Nature's Prophet's treants.
* Luna can easily cancel Teleportation with her Lucent Beam.
* Even though Nature's Prophet can evade all of Luna's abilities with Shadow Blade, a smart Luna will always buy Dust of Appearance to provide vision on Shadow Fiend to her and her team.

* Pugna is a very fragile hero who can easily get caught and killed by Storm Spirit's long range initiation.
* This is especially true if he has Orchid Malevolence or Scythe of Vyse.
* Pugna has no disables that can prevent Storm Spirit from escaping.
* Even though Ball Lightning requires high amount of mana, Nether Ward is ineffective since Storm Spirit is invulnerable while using it.
* Storm Spirit's other abilities cost very insignificant amount of mana for Nether Ward to be effective.

* Ball Lightning can be used to clear Nature's Prophet's Treants and easily destroys Sprout.
* Electric Vortex prevents Nature's Prophet's escaping using Teleportation.

* Pugna's Nether Ward doesn't really hurt Meepo since he usually buys attribute items to tank up and can be killed very quickly by 4 clones. Decrepify can amplify Poof's damage should Pugna use it to avoid Meepo's right clicking.

* Nature's Prophet is heavily countered by Meepo, not only Meepo can kill the treants with a single Poof, but he can also stop Nature's Prophet from using Teleportation, and can gain vision inside Sprout.

Additional:
* Meepo can net Nature's Prophet's treants with Earthbind and then Poof them, putting an end to his pushing.
* Skilled Meepos can rival and even exceed Nature's Prophet's global presence by combining Poof with Boots of Travel, meaning that he can not only stop his push, but also can kill him if he is not careful.

* Fragile heroes: Bounty Hunter has decent nuking capabilities with Shiruken Toss and Jinada thus making fragile heroes easy picks for ganking. Few examples of such heroes are:Crystal Maiden, Pugna, Skywrath Mage, Io, Witch Doctor, etc.

* Heroes who can provide True Sight or semi-reveal enemy heroes as Nature's Prophet is prone to buying Shadow Blade: Bounty Hunter, Slardar, Spectre, Spirit Breaker.

* Heroes who rely on channeling abilities can be interrupted in teamfights by Rolling Thunder: Crystal Maiden, Pugna, Witch Doctor

* Heroes who have summons, which can be quickly cleared by his powerful area of effect skill: Nature's Prophet, Enigma, Lycan

* Nature's Prophet has no innate way to deal with Gravekeeper's Cloak or kill {U:Familiar}s effectively.
* Familiars can fly over the trees created by Sprout. They can also use Stone Form when Nature's Prophet is trying to use Teleportation.
* Aghanim's Shard upgraded Stone Form alow allows Visage himself to stun Nature's Prophet whenever he is trying to use Teleportation.
* Aghanim's Scepter gives Visage Silent as the Grave ability, which allows him and his {U:Familiar}s to either escape from Nature's Prophet or give him a surprise attack.
Additional:
* Nature's Prophet has no natural method of dealing with Gravekeeper's Cloak and Familiars.
* Familiar's low base attack time can chip away Nature Prophet's health.
* Familiar's Stone Form destroys trees created by Sprout.
* Familiars can scout woods and foggy areas where Nature's Prophet is trying to use Teleportation.

* Sprout cannot protect Nature's Prophet if Broodmother puts down a web.
* Nature's Prophet's low mobility means he is defenseless against Incapacitating Bite.
* Spiderlings can absorb much of the damage from Wrath of Nature.
Additional:
* Broodmother can destroy Nature's Prophet's Treants with Spawn Spiderlings and summon spiderlings in their place.
* Broodmother loves buying Orchid Malevolence, which can prevent Nature's Prophet from escaping with Sprout and Teleportation.

* Sprout will not protect Nature's Prophet from Huskar if he has already locked on with Life Break.
* Even a farmed Nature's Prophet is usually not durable enough to fight Huskar alone.

* Undying's Tombstone will cheerfully chew through treants, incidentally netting you some extra income during fights.
* The above interaction tends to ensure that skirmishes are heavily populated with units, thereby buffing Soul Rip

* Pugna is very reliant on his abilities for damage which Silencer can take advantage off. But he has to be careful around the Nether Ward as Silencer's abilities cost a lot of mana to use.

* If Ursa uses Enrage, Pugna's Life Drain is next to worthless against him, due to Ursa taking 80% less damage, therefor Pugna heals by only 20% of the damage that the spell normally deals.
* It also dispels Decrepify, Even if you wait until he casted it, he can still dispel it with Shard upgraded Earthshock
* Ursa also commonly builds Skull Basher. With his high Attack Speed from Overpower. he can easily cancel Life Drain
* If Decrepify is defensivly casted, Ursa can still cast Earthshock both to slow you, and to deal amplified magic damage. He also commonly builds a Nullifier
* If Ursa jumps on you with a Blink Dagger he can easily wipe you out with Overpower.
* Ursa's Overpower can destroy a full health Nether Ward and still have a few swipes leftover, Also Ursa's low mana spells means he takes negligible damage from the Nether ward anyway.
* Ursa is also a common Diffusal Blade carrier, using it to both amplify his damage, but as his primary way to catch fleeing heroes
* Pugna is also the primary target of Ursa, due to him being both quite squishy, and a serious threat to his team, Ursa prioritizes the weakest link as Fury Swipes stacking damage will quickly demolish them, allowing Ursa to safely switch heroes

* Nature's Prophet is often by himself. Clinkz can use invisibility to hunt him down and kill him, although a Quelling Blade may be needed to cut through his Sprout. Orchid Malevolence may also be needed if 3-4 seconds are not enough time to kill him, as he can teleport away.
* Clinkz can match Nature's Prophet's ability to split push.

* All of Pugna's damage is magical, which can get blocked by Fate's Edict's 100% magic resistance.
* Oracle has two abilities that apply a dispel, which can easily remove Decrepify on his ally or Oracle.

* Naga Siren is a natural split-pusher. With Rip Tide, she will easily out-push Nature's Prophet, farming his treants in the process.
* Ensnare prevents Teleportation. Even if he hides inside Sprout, Song of the Siren lasts long enough to prevent him from escaping.
Additional:
* Naga Siren is a natural split-pusher. With a Radiance equipped, she will easily keep the lanes pushed out, therefore keeping backdoor protection enabled and preventing Nature's Prophet from dealing building damage.
* Ensnare prevents Teleportation.
* Song of the Siren will stop Nature's Prophet from escaping even if he has hidden inside of Sprout.

* Firestorm makes quick work of Treants and Atrophy Aura gives him temporary damage for every Treant killed.
* Pit of Malice can stop Teleportation channeling.
* Atrophy Aura greatly reduces Nature's Prophet's damage and he has no other good way to deal damage.
* Fiend's Gate can counter split-pushing, which is something that Nature's Prophet relies on a lot.

* Starbreaker and Celestial Hammer does high AoE damage which easily clears {U:Treant}, shutting down most of Nature's Prophets damage and pushing power.
* Dawnbreaker can teleport to deal with split-pushing Nature's Prophet and rejoin her team with Solar Guardian when they require it.
* Since Starbreaker clears trees in its path followed by a stun at the end Nature's Prophet will be unable to escape the dangerous situation by using Sprout on himself and teleporting away with either Teleportation or Town Portal Scroll.
Additional:
* Starbreaker and Celestial Hammer does high AoE damage which easily clears {U:Treant}, shutting down most of Nature's Prophets damage and pushing power.
* Dawnbreaker can teleport to deal with split-pushing Nature's Prophet and rejoin her team with Solar Guardian when they require it.
* Since Starbreaker clears trees in its path followed by a stun at the end Nature's Prophet will be unable to escape the dangerous situation by using Sprout on himself and teleporting away with either Teleportation or Town Portal Scroll.

* Astral Spirit can give Elder Titan a lot of damage and movement speed if Nature's Prophet sends all of his Treants together.
* Not only does Echo Stomp prevent Nature's Prophet from escaping using Teleportation, but Astral Spirit can be used to bypass Sprout and cancel Teleportation with it's own Echo Stomp from long distances.
* Earth Splitter can clear Nature's Prophet's Treants effectively.

* Phantom Lancer creates way too many illusions for Pugna's Life Drain to destroy, overwhelming him easily.
* Doppelganger can dodge Nether Blast or dispel Decrepify.
* Diffusal Blade is a common item for Phantom Lancer to burn Pugna's large mana pool and deals a large amount of damage in the process.
Additional:
* Though Life Drain instantly destroys illusions, Phantom Lancer creates way too many for Pugna to handle.
* A good Phantom Lancer will also dodge your Nether Blast with Doppelganger.
* Phantom Lancer is the most natural Diffusal Blade carrier to burn Pugna's very large pool of mana away and deal a large amount of damage in the process.

* Heroes with no mobility will take some good damage from Sand King's spells: Dragon Knight, Jakiro, Pugna, Earthshaker,...

* Sand King's Caustic Finale combined with Sand Storm will kill Treants easily.
* Sand King can interrupt Teleportation with Burrowstrike, even through Sprout.
Additional:
* With Caustic Finale, Sand King can easily kill the treants from Nature's Call.
* Burrowstrike allows Sand King to prevent Nature's Prophet from using Teleportation inside of his Sprout.

* Pugna's low health and reliance on channeled abilities make him very vulnerable to Tusk, although Pugna can win in a straight up 1v1 later in the game.

* Shadow Shaman's Mass Serpent Ward together with Ether Shock can easily kill lots of Treants if played defensively.
* Hex and Shackles can disrupt Nature's Prophet's escape attempts with Teleportation.
Additional:
* Mass Serpent Ward can kill lots of treants if played defensively.
* Mass Serpent Ward, Hex and Shackles can catch and kill a Nature's Prophet trying to use Teleportation.

* Spirit Breaker can chase Nature's Prophet from anywhere on the map with Charge of Darkness, making it hard for Nature's Prophet to split-push.
* Charge of Darkness and Nether Strike gives vision of Nature's Prophet when he tries to Sprout himself and teleport away.
Additional:
* Charge of Darkness allows Spirit Breaker to catch Nature's Prophet out when he tries to split push.
* Nature's Prophet can't hide in his Sprout against Spirit Breaker, as his Charge of Darkness provides vision on its target.
* Spirit Breaker can easily cancel Nature's Prophet's Teleportation.

* Ember Spirit can easily deal with Nature's Call by using his Flame Guard and with Battle Fury. He also has multiple ways of escaping Sprout. Additionally, Ember Spirit can break Sprout's trees with Activate Fire Remnant and interrupt Teleportation with Searing Chains.
Additional:
* Sleight of Fist with Battle Fury deals a lot of damage to Nature's Prophet's team if they stand close to his Treants, as well as killing all the Treants with ease.
* Ember Spirit with Fire Remnant and Boots of Travel can be very active around the map, which enables him to quickly teleport and defend the objective Nature's Prophet is attacking whenever he tries to push.

* Nature's Prophet treants can be cleared by Ignite or Multicast Hand of Midas
* Fireblast and Unrefined Fireblast prevents Nature's Prophet from using Teleportation.

* Firefly can be used to clear Nature's Prophet's Treants and allows Batrider destroy Sprout's trees.
* Flaming Lasso prevents Nature's Prophet from escaping using Teleportation.

* Sprout can't stop her to Rebound.
* Treants can be used as targets for Rebound and Dispose as well.

* Life Drain does not instantly kill the illusions from Phantasm
* Chaos Bolt and Reality Rift can easily interrupt the channeling from Life Drain.
* Reality Rift makes it harder for Pugna to keep his distance between Chaos Knight.
* Nether Ward barely deals any significant damage on Chaos Knight as Chaos Knight's abilities do not cost a lot of mana
* The overwhelming damage of Chaos Knight and his illusions will do a quick work on Pugna's poor HP pool, or safely remove the Nether Ward from the battlefield.

* Doom can eats Nature's Prophet's treants with Devour and gains lots of gold.
* Doom can buy Radiance or use his Scorched Earth to quickly wipe out a swarm of Treants.
* Doom and a ministun from Infernal Blade's prevents Nature's Prophet from escaping with Sprout and Teleportation.

* Heroes who produce many summons will have a hard time against Storm's Dispel Magic during teamfight: Broodmother, Enigma, Nature's Prophet.

* Heroes who can provide True Sight or semi-reveal enemy heroes as Nature's Prophet is prone to buying Shadow Blade: Bounty Hunter, Slardar, Spectre, Spirit Breaker.

* Keeper of the Light can stall pushes with Illuminate. This makes him strong against pushing heroes: Terrorblade Naga siren Nature's Prophet and Anti-Mage

* Most summons and illusions can barely hurt Tidehunter at all, after their attacks get reduced by Anchor Smash and blocked by Kraken Shell: Nature's Prophet, Enigma
* Also Ravage's large area of effect and damage can easily damage all those units at once, or just straight up clear them.

* Mass summoning heroes: Broodmother, Nature's Prophet and Enigma all have summons Puck can clear clear with Illusory Orb and Waning Rift instantly, due to their summons having low health.

* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.
* In general, highly mobile heroes like Earth Spirit or Storm Spirit are at a disadvantage against X Marks the Spot.
* Similarly, heroes with low cooldown teleports can be afraid to split push against X Marks the Spot, such as Tinker and Nature's Prophet.

* Heroes that have AoE damage: Lina, Keeper of the Light, Timbersaw, Leshrac, Bristleback, Axe

* Once caught in Bear's Entangle, Nature's Prophet cannot escape with Teleportation.

* Nature's Prophet is extremely easy to gank with Relocate while he's split pushing.
* Tether on a friendly unit can destroy Nature Prophet's trees should he surround himself with Sprout as a defense.

* Sprout will not protect Nature's Prophet from Tree Dance.
* Boundless Strike will interrupt attempts at Teleportation, and can reach Nature's Prophet inside the tree line.

* Nature's Prophet's low mobility and health pool allow Phantom Assassin to destroy him in the early game.
* Phantom Strike allows Phantom Assassin to jump in and out of Sprout, provided she has vision.

* Nature's Prophet's Sprout can be broken by Muerta's Dead Shot.
* Gunslinger will quickly dispatch of the Treants from Nature's Call.
* The Calling will greatly reduce the potential damage Treants can do.

* Sniper's huge range makes him an unviable target to use Life Drain on, forcing Pugna to risk playing out of position to use it on Sniper.
* Sniper's Shrapnel can be used to provide vision on Nether Ward, and his range allows him to easily take it out.
* A clumsy Pugna may accidentally boost Sniper's Shrapnel and Assassinate damages if he recklessly uses Decrepify on himself or his allies.