* Queen of Pain usually outlanes Invoker, giving her team a significant early game advantage while Invoker is still farming.
* Blink allows Queen of Pain to escape from Invoker's combo if he doesn't have disables.

* Crippling Fear is a good way to shut down and gank Invoker in the early game..
* Void deals good damage to Invoker and makes escaping harder.
* With Hunter in the Night and Void, Invoker can't get away from Night Stalker and won't be able to catch him with Sun Strike during the night.

* Heroes with high burst damage: Lina, Lion, Luna, Nyx Assassin, Queen of Pain.

* Void can be used to cancel Requiem of Souls.
* Crippling Fear prevents Shadow Fiend from using Shadowraze or Requiem of Souls.
* With Dark Ascension and Gem of True Sight, Night Stalker can find and kill Shadow Fiend easily. He is also a tanky hero that can fight Shadow Fiend at any stage of the game.

* Heroes with teleports to escape Solar Blind and Will-O-Wisp: Phantom Assassin, Puck, Queen of Pain, Storm Spirit

* Crippling Fear prevents Keeper of the Light from using his spells to keep his team alive during team-fights.
* Dark Ascension is very strong against Keeper of the Light, as it allows Night Stalker to jump the backline and quickly kill the squishy Ezalor, especially when combined with the slow from Void.
Additional:
* Keeper of the Light's Aghanim's Scepter upgrade loses much of its power, due to Night Stalker being able to reduce the duration of daytime by a lot.

* Blink allows Quen of Pain to easily escape ganking or initiating attempts with Hookshot and Power Cogs.

* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.

* Blink makes it hard for Gyrocopter to pin down Queen of Pain.
* Sonic Wave is very effective at ganking Gyrocopter in the early game.

* Heroes with weaker mobility will struggle to keep up with Night Stalker: Gyrocopter, Ursa, Drow Ranger

* Queen of Pain can easily escape Chain Frost thanks to Blink.
* His low survivability makes an easy kill for Shadow Strike, Scream of Pain & Sonic Wave.

* Heroes with low health: Lich, Crystal Maiden, Lion.

* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.

* The long silence of Crippling Fear at night prevents Mirana from escaping with Moonlight Shadow and Leap. She also has really low base health, so Night Stalker can usually kill her during one cast of Crippling Fear at night.
* With Dark Ascension and Gem of True Sight, Night Stalker can find and kill Mirana, and he is a tanky hero capable of fighting Mirana any stage of the game.

* Both Scream of Pain and Sonic Wave should hit him during his Shadow Dance.

* With Dark Ascension he can keep vision on Slark, disabling his Shadow Dance regeneration.
* Night Stalker is very fast so without the Pounce in lane, he can simply out distance him during the night.
* Slark is matched in night vision by only a few heroes, Night Stalker happens to be one of them.

* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, Queen of Pain, Phantom Assassin, Windranger, Bounty Hunter, Spirit Breaker, Night Stalker, Storm Spirit, Juggernaut, etc.

* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, Queen of Pain, Phantom Assassin, Windranger, Bounty Hunter, Spirit Breaker, Night Stalker, Storm Spirit, Juggernaut, etc.

* Crippling Fear silences nearby heroes and cannot be dispelled, which hinders Rubick's way to retaliate when being jumped on.
* With Hunter in the Night and Dark Ascension, Night Stalker can find Rubick easily in teamfights. The two spells grants more than enough damage to hunt Rubick down without defensive items.

* Queen of Pain can Blink to both escape and initiate onto Void Spirit.
* She is also a very common Orchid Malevolence carrier, which can prevent Void Spirit from contributing much in fights.

* Once you farm up an Orchid Malevolence or a Scythe of Vyse, you're suddenly a lot more fearsome to elusive heroes like Storm Spirit or even that pesky Puck.

* Puck cannot use any of its normal means to survive should Night Stalker catch it within Crippling Fear, and goes down quickly.
Additional:
* Void is a potent nuke that is devastating to Puck's low health pool.
* Crippling Fear silence can prevent Puck from casting spells, leaving it vulnerable.

* Dark Ascension also allows Night Stalker to fly over Proximity Mines without triggering them.
* Crippling Fear is effective in stopping Techies from using Blast Off and Void is effective in stopping them from running to the safety of their mines.

* Once you farm up an Orchid Malevolence or a Scythe of Vyse, you're suddenly a lot more fearsome to elusive heroes like Storm Spirit or even that pesky Puck.

* Storm Spirit is absolutely helpless if caught within Night Stalker's silence range.
* Common items a Storm Spirit will build will not remove the AoE silence.
Additional:
* Crippling Fear is a silence that can last up to 8 seconds during night, rendering Storm Spirit tied limited to his items in a fight.
* Dark Ascension allows Night Stalker to initiate on Storm Spirit across the impassable terrain around the middle lane, rendering Storm vulnerable in the early game and prevent him from snowballing.

* The long silence of Crippling Fear at night prevents Weaver from using his Shukuchi or Time Lapse.
* With Dark Ascension and Gem of True Sight, Night Stalker can easily find and probably kill Weaver.
* Hunter In the Night's attack speed bonus removes The Swarm's beetles very quickly.

* Dark Ascension reduces vision for the enemy team, which makes it more difficult for Magnus to initiate with Blink Dagger and Reverse Polarity. It is also more likely that Night Stalker will scout out Magnus with Aghanim's Scepter and a Gem of True Sight, after which he can silence Magnus with Crippling Fear.

* Often you can burst Drow Ranger down before she has a chance to try and Gust you away. Try to have a teammate bait her Gust out before you Blink and get the drop on her.

* Heroes with weaker mobility will struggle to keep up with Night Stalker: Gyrocopter, Ursa, Drow Ranger

* The long silence at night prevents Clinkz from escaping with invisibility if Night Stalker can sneak up on him. He also has really low base health, so Night Stalker can usually kill him alone during one cast of Crippling Fear at night.

* He's the kind of hero that likes to remain at low hp, which is perfect for Queen of Pain to burst with Sonic Wave.
* You should be able to blink away after he jumps on you with Life Break.

* Night Stalker is one of the best heroes to find (and silence) Tinker in the trees during Dark Ascension.
Additional:
* Night Stalker can easily find Tinker in the trees during Dark Ascension.
* Void's mini-stun will stop Rearm and Boots of Travel.
* Crippling Fear's silence will prevent Tinker from fighting back, as Tinker relies on his spells.

* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, Io, Nature's Prophet, Pangolier, Puck, Queen of Pain and most notably Riki.

* Heroes with mobility spells can quickly escape from Stroke of Fate or break out of Soulbind: Anti-Mage, Queen of Pain, Morphling, Storm Spirit

* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage

Additional:
* Untouchable won't mitigate magic damage, and a squishy Enchantress is very vulnerable to Queen of Pain's magic burst.

* Timbersaw has a difficult time against magical and pure damage: Lina, Leshrac, Enchantress, Queen of Pain

* Heroes with considerable mobility can easily escape from a rolling Pangolier: Anti-Mage, Queen of Pain, Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, moreover, if a player is familiar with how Rolling Thunder works, they can adjust their movement to avoid it entirely and of course outplay the Pangolier player.

* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: Meepo, Witch Doctor, Lycan, Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: Phantom Lancer, Chaos Knight, Naga Siren (bonus for her Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna

* Queen of Pain can be a good hero for dealing with Ember Spirit with Orchid Malevolence, her pure damage nuke in Sonic Wave and a slow in Shadow Strike. However, Queen of Pain can be punished by Ember Spirit, as his Searing Chains prevents her from getting Blink off.

* Heroes that usually builds Linken's Sphere as a core item: Weaver, Medusa, Morphling, Queen of Pain, Storm Spirit

* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.

* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with Hookshot) can easily avoid Lil' Shredder and Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.

* Heroes with a high degree of mobility and invisibility are hard to catch with Meat Hook: Ember Spirit, Riki, Clinkz, Queen of Pain.

* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.

Additional:
* Void's mini-stun and silence from Crippling Fear will stop Pudge from using Dismember or turning off his Rot.
* Night Stalker has naturally high health, strength gain and common itemization for survivability through magic resistance, making Night Stalker a poor target for Pudge.

* Heroes with low mobility that rely on spells: Zeus, Lina, Crystal Maiden.

* Durable heroes can stand against Tusk during 1v1: Axe, Dragon Knight, Night Stalker, Centaur Warrunner, Wraith King and more.

* Heroes who have a high mobility (Queen of Pain, Storm Spirit, Slark, etc.).

* Heroes with low mobility that rely on spells: Zeus, Lina, Crystal Maiden.

* Heroes that have long silences, such as Night Stalker and Silencer, will prevent Abaddon from saving his allies effectively and disable the active component of Borrowed Time.

* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .

* Careful not to blink into Riki's Smoke Screen or Night Stalker's Crippling Fear, as these field effects will instantly silence Earthshaker and prevent him from initiating.

Additional:
* Fissure has a short stun and creates an impassable ridge. However, Night Stalker can fly over it during Dark Ascension.
* Night Stalker can find Earthshaker, disable his Blink Dagger with Void, and then take him out with Crippling Fear.
* Earthshaker may fail his blink combo against Night Stalker's team if he is not careful, as he can blink into the silence.

* Night Stalker's Crippling Fear at night prevents Shadow Walk for an extended period of time and his Void will make Phase Boots useless. If Night Stalker has True Sight, he can shutdown Bounty Hunter's sneak kill.

* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.

* Heroes with long disables, like Lion, Night Stalker, or Legion Commander, can prevent Oracle from using spells or items.

* Dark Seer's only disable is Vacuum. Though he starts off with high armor and health, he'll eventually have a hard time dealing with high mobility heroes such as Weaver or Queen of Pain.

* Blinking heroes like Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.

* Heroes with damage over time abilities can quickly eat through Gravekeeper's Cloak charges like Huskar, Jakiro and Queen of Pain.

* Heroes that have a weak laning stage: Spectre, Nyx Assassin, Clockwerk, Spirit Breaker, Omniknight, Pudge.

* All of Queen of Pain's abilities are active, making Demonic Purge break from Aghanim's Scepter useless.
* However, Demonic Purge can help his allies kill a squishy Queen of Pain.
* Blink allows Queen of Pain to escape from Shadow Demon's abilities if he doesn't have disables.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Sonic Wave for the enemy.
* Queen of Pain usually builds Eul's Scepter of Divinity to dispel Shadow Poison and Soul Catcher and Linken's Sphere or Spell Block talent to block Disruption and Demonic Purge.

* Blink allows Queen of Pain to avoid ganks and keep her distance, preventing Monkey King from building up Jingu Mastery.
* Scream of Pain and Sonic Wave will hit Monkey King when he is disguised, or on a tree.
* The large AoE and low cooldown also helps Queen of Pain hit the real Monkey King inside of Wukong's Command.

* Crippling Fear makes it so Axe might use Blink Dagger right into an AoE silence in the middle of everyone.
* Void cripples Axe's already bad movement speed and attack speed.
* Hunter in the Night makes it impossible for Axe to catch up to a fleeing or escape from Night Stalker during the night.
* Lastly, Dark Ascension gives full vision over Axe before he initiates, making the opponents all recognise his location immediately and allowing Night Stalker to prevent it or vocally tell his team if needed.
* Night Stalker has very high strength gain, even in lane, so a successful Culling Blade is very unlikely.
* Axe's Blade Mail will likely do nothing to Night Stalker because of his high health and certain requirements for him to do the most damage to be true.

* Void can interrupt Icarus Dive.
* His Crippling Fear's silence will shutdown a spell caster Phoenix.
* However, Phoenix punishes Night Stalker with Supernova because it will turn night into day, and it has a higher priority than Dark Ascension, effectively canceling the passive bonuses Night Stalker gets from Hunter in the Night.

* Blink can instantly break Static Link, making it useless against her.
* Queen of Pain doesn't fully rely on her physical attack damage, so she can still fight after being hit with Static Link.

* Heroes with low health: Lich, Crystal Maiden, Lion.

* Crippling Fear can silence Faceless Void for a long time, preventing him from using his Time Walk and Chronosphere.

* Heroes with low mobility that rely on spells: Zeus, Lina, Crystal Maiden.

* Heroes with escaping and disjointing abilities can be good against Juggernaut:Anti-Mage Riki, Queen of Pain, Puck, Storm Spirit, Ember Spirit, Slark etc.

* Heroes with weaker mobility will struggle to keep up with Night Stalker: Gyrocopter, Ursa, Drow Ranger

* Crippling Fear makes Night Stalker one of the best early game gankers to shut down Anti-Mage.
* Night Stalker's low mana pool causes him to take little damage from Mana Void.

* With Dark Ascension and Gem of True Sight, Night Stalker can easily find and kill Riki. Riki will also find it harder to kill the tanky Night Stalker than he would many other heroes.