Queen of Pain
* 
Glaives of Wisdom's intelligence steal will heavily punish Queen of Pain, as the loss of intelligence means that her mana pool is also reduced, since she is heavily reliant on her abilities to be able to make an impact.
* In the laning stage, Queen of Pain's reliance on spamming Shadow Strike and Scream of Pain will be significantly hindered by 
Arcane Curse.
* 
Last Word and 
Global Silence will render Queen of Pain defenseless unless she has an item/ally to dispel the silence.
Outworld Destroyer
* Silencer's 
Intelligence Steal will heavily reduce Outworld Destroyer's damage output, particularly from Sanity's Eclipse.
* Last Word and Global Silence will take Outworld Destroyer out of the fight unless he has built Black King Bar.
Additional:
* Silencer's intelligence steal will heavily reduce Outworld Destroyer's damage output, especially if Destroyer dies a lot near Silencer and loses intelligence permanently.
* Global Silence and Last Word will render Outworld Destroyer helpless unless he has an item/ally to dispel silence.
Queen of Pain
* All of Queen of Pain's abilities are worthy choices for Rubick to 
Spell Steal. In addition, he can cast her abilities from further distances than her thanks to 
Arcane Supremacy's increased cast range and spell amplification.
Outworld Destroyer
* Rubick can use Spell Steal to steal Astral Imprisonment, and if Rubick gets 
Aghanim's Scepter he gets 2 charges of it. This can overpower Outworld Destroyer in team fights.
* Rubick can also steal Sanity's Eclipse against Outworld Destroyer's teammates.
Queen of Pain
* Night Stalker has a huge, almost instant silence through 
Crippling Fear. The main problem is that he can get it off while Queen of Pain barely has any vision of him if he creeps up to her during 
Dark Ascension. She'll have to play very carefully before she gets a 
Black King Bar or a 
Eul's Scepter of Divinity.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: 
Death Prophet, 
Night Stalker, 
Drow Ranger, 
Doom .
Queen of Pain
* In early to mid stage, Silence is also a great way to counter escape oriented heroes such as 
Anti-Mage, 
Queen of Pain, and 
Phantom Assassin to prevent them from escaping, provided that they don't have any basic dispels.
Additional:
* 
Silence will prevent Queen of Pain from using Blink to escape or chase.
* If Queen of Pain uses Blink to close the gap to Death Prophet, Death Prophet will be in range for 
Spirit Siphon and typically gain an advantage over Queen of Pain.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .
Queen of Pain
* Sonic Wave is a bad choice in abilities if he and the 
Tempest Double both use 
Blade Mail to reflect the damage to Queen of Pain, potentially killing her outright if her health is low enough.
* 
Magnetic Field protects himself or his ally from Queen of Pain's attacks unless she has 
Monkey King Bar.
* One more advantage of Tempest Double is that he can deny himself if he is close to death with Shadow Strike's debuff.
Queen of Pain
* Shadow Shaman has many disables to lock down Queen of Pain, preventing her from Blinking away, even through 
Linken's Sphere or her spell block talent.
* 
Mass Serpent Ward can tear through Queen of Pain's low health pool once she's locked down by 
Hex & 
Shackles.
Queen of Pain
* Blood Rite prevents Queen of Pain from escaping with 
Blink.
* Blink will trigger the extra damage from Rupture.
Additional:
* 
Blood Rite silences her, preventing her from initiating or escaping.
* With 
Thirst, even if she Blinks away, Bloodseeker can catch right up to her.
* 
Rupture will heavily damage Queen of Pain if she tries to Blink away.
* She is, however, one of the few heroes who can avoid the damage from Rupture if she successfully blink-walks.
Queen of Pain
* A good Centaur can catch Queen of Pain with a 
Blink Dagger and 
Hoof Stomp.
* 
Retaliate with Blade Mail reflects all of Queen of Pain's damage, especially Sonic Wave.
* 
Stampede grants a movement speed bonus, which can prevent Queen of Pain from initiating.
* 
Double Edge can shred her low health pool if she's not careful.
Queen of Pain
* Lina has a very long range of attack, which completely overlaps the range of Queen of Pain's abilities and attacks, which is why even a single 
Shadow Strike roll can become deplorable, since Lina will shoot Queen of Pain from a long distance before and after the Shadow Strike roll. And with the help of the abilities of 
Light Strike Array and 
Laguna Blade, Lina can even kill Queen of Pain because of her small health reserve if she is exposed to a blow
Additional:
* Lina has a very long range of attack, which completely overlaps the range of Queen of Pain's abilities and attacks, which is why even a single Shadow Strike roll can become deplorable, since Lina will shoot Queen of Pain from a long distance before and after the Shadow Strike roll. And with the help of Light Strike Array and Laguna Blade, Lina can even kill Queen of Pain because of her small health reserve if she is exposed to a blow.
Queen of Pain
* Chain of Earthbinds prevents her from using Blink, allowing Meepo to quickly kill her with Poof and attacks.
* Meepo tends to buy items with attributes, mitigating Queen of Pain's magical burst.
Additional:
* Meepo is the hard counter for Queen of Pain - chaining 
Earthbinds prevents her from using Blink for a long time, and without any other escape options, Queen of Pain cannot survive several 
Poofs and attacks.
* Meepo tends to build items with attributes, mitigating Queen of Pain's magical burst.
Queen of Pain
* Blink and positioning is crucial for Queen of Pain. These factors are heavily countered by a good Glimpse.
* Static Storm is devastating for Queen as she relies heavily on her spells to inflict heavy burst damage.
Additional:
* 
Thunder Strike gives vision of Queen of Pain when she's trying to escape. When combined with 
Glimpse, her mobility and hit-and-run style can be negated.
* While in a team fight, 
Static Storm forces Queen of Pain to only use right-clicks.
* When combined with the 
Kinetic Field, she can only wait until she respawns.
Queen of Pain
* Smoke Cloud prevents Queen of Pain from using any of her offensive and defensive spells, rendering her unable to effectively react to Riki's attack.
* It's easy to dodge 
Sonic Wave by using Blink Strike & Tricks of the Trade.
Outworld Destroyer
* 
Doppelganger and 
Juxtapose allow Phantom Lancer to initiate on Outworld Destroyer, and, although Arcane Orb will normally destroy his illusions instantly, Phantom Lancer will spawn too many to deal with without using Sanity's Eclipse.
* Outworld Destroyer has very little AOE ability; His Astral Imprisonment with Aghanim's Scepter is his primary AOE, and it does too little damage to eliminate Phantom Lancer's illusions.
Additional:
* Although Outworld Destroyer will typically destroy Phantom Lancer's illusions in one shot, Phantom Lancer spawns too many of them for Outworld Destroyer to deal with. However, be careful about initating on Outworld, as 
Sanity's Eclipse will erase your illusions and deal massive damage to you. He can then follow up with 
Astral Imprisonment and 
Meteor Hammer.
Outworld Destroyer
* 
Tinker's 
Laser is useful against Outworld Destroyer, as the blind prevents him from landing Arcane Orbs.
Outworld Destroyer
* Heroes with built-in spell immunity can become immune to all of Outworld Destroyer's spells: 
Lifestealer's 
Rage and 
Juggernaut's 
Blade Fury.
Outworld Destroyer
* Any heroes with high intelligence, such as 
Invoker and 
Pugna.
Queen of Pain
* Heroes with mobility spells like Queen of Pain, Anti-Mage, Phantom Assassin, 
Riki, 
Puck, and 
Spirit Breaker that are cancelled by Frostbite can suffer greatly from the presence of Crystal Maiden. It is absolutely critical, however, to have followup from teammates, as all of the above heroes can make quick work of the squishy Crystal Maiden after they are released from her grip.
Queen of Pain
* High priority targets like Queen of Pain, Drow Ranger, 
Ember Spirit can't get caught out from 
Lion's long range disables, making it harder to them fulfill their roles, and making it easy to target them.
Queen of Pain
* Heroes who rely on high mobility are especially vulnerable to Primal Roar: 
Storm Spirit, Ember Spirit, Queen of Pain.
Queen of Pain
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for 
Lucent Beam & 
Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Additional:
* Aggressively blinking is not going to end well against Luna, because Queen of Pain will be an easy target for Lucent Beam & Eclipse.
* Queen of Pain's HP is abysmal, so Luna can quickly kill Queen of Pain as soon as she initiates with Blink.
Outworld Destroyer
* Every hero that can withstand or prevent Eclipse at level 7: Juggernaut, Riki, 
Clockwerk, Drow Ranger, 
Abaddon, 
Faceless Void, 
Weaver, 
Outworld Destroyer.
Queen of Pain
* Time Dilation affects Queen of Pain's low cooldown abilities, making them unusable for a long time, rendering Queen of Pain nearly useless.
* Chronosphere provides excellent lockdown against Queen of Pain, allowing for reliable kills in all stages of the game.
Additional:
* 
Time Walk and 
Backtrack allows Faceless Void to easily negate Queen of Pain's burst damage.
* 
Chronosphere prevents Queen of Pain from escaping with Blink, and her low survivability makes her an easy kill.
* 
Time Dilation will prevent Queen of Pain from using her low-cooldown spells or force her to buy Black King Bar or a Eul's Scepter of Divinity to dispel the debuff and re-engage.
Outworld Destroyer
* Any hero that can nullify effects of Chronosphere: (
Keeper of the Light with Aghanim's Scepter during daytime, 
Winter Wyvern), banishing him or Faceless Void (Outworld Destroyer, 
Shadow Demon, 
Earth Spirit with Aghanim's Scepter) or protecting him in other ways (
Dazzle, 
Oracle, Abaddon) can greatly limit Chronosphere's potential.
Outworld Destroyer
* As Outworld Destroyer has short cast ranges, a short attack range, and no gap-closing abilities, Sniper can kite and harass Outworld Destroyer in lane with his long range and zone him out in fights. The continuous area damage from 
Shrapnel also prevents Astral-Blink escapes.
* However, in the late game, Outworld Destroyer's massive damage can overwhelm Sniper once he obtains Blink Dagger, 
Force Staff etc. to close the gap.
Queen of Pain
* Heroes with high mobility can approach Sniper: Anti-Mage, Earth Spirit, 
Io, 
Nature's Prophet, 
Pangolier, Puck, Queen of Pain and most notably Riki.
Outworld Destroyer
* 
Refraction blocks most of the damage dealt with Arcane Orb and Sanity's Eclipse if used correctly, and is difficult for Outworld Destroyer to deal with.
* If Astral Imprisonment is on cooldown, then an Outworld Destroyer slowed by 
Psionic Trap is an easy kill for Templar Assassin, especially during the laning stage.
Queen of Pain
* Weak damage but high tick rate or persist in a long time: 
Slark, 
Gyrocopter, Queen of Pain, 
Shadow Shaman (Shackles), 
Jakiro, Pugna, Doom
* Heroes that can quickly deal damage to her, regardless of how weak they are, can easily break through her Refraction:
* Multiple attackers thanks to summoned units or clones: 
Meepo, 
Witch Doctor, 
Lycan, 
Enigma, Shadow Shaman
* Multiple attackers thanks to illusions: 
Phantom Lancer, 
Chaos Knight, 
Naga Siren (bonus for her 
Ensnare). Also despite the visual effects, Templar Assassin does not spill damage against illusions or buildings, so she is not a really good hero to clean up illusions.
* Weak damage but high tick rate or persist in a long time: Slark, Gyrocopter, Queen of Pain, Shadow Shaman (Shackles), Jakiro, Pugna, Doom
Queen of Pain
* Heroes reliant on abilities to output damage or escape can be shut down by Gust: Queen of Pain.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .
Queen of Pain
* Often you can burst Drow Ranger down before she has a chance to try and 
Gust you away. Try to have a teammate bait her Gust out before you Blink and get the drop on her.
Queen of Pain
* Blink can instantly break Static Link, making it useless against her.
* Queen of Pain doesn't fully rely on her physical attack damage, so she can still fight after being hit with Static Link.
Outworld Destroyer
* Outworld Destroyer doesn't care if Razor steals his damage because he does most of his damage through 
Arcane Orb.
* Astral Imprisonment can prevent Razor from using the stolen damage from Static Link or chasing with Eye of the Storm.
* Sanity's Eclipse will do a ton of damage to Razor due to his low mana pool.
Queen of Pain
* Heroes with considerable mobility can easily escape from a rolling Pangolier: Anti-Mage, Queen of Pain, 
Void Spirit, Storm Spirit, Ember Spirit, Earth Spirit, moreover, if a player is familiar with how Rolling Thunder works, they can adjust their movement to avoid it entirely and of course outplay the Pangolier player.
Outworld Destroyer
* Astral Imprisonment protects an ally for much of Rolling Thunder's duration, especially at the lower levels. As Rolling Thunder has a considerable cast animation, an Outworld Destroyer with Blink Dagger can initiate on him and destroy his timing.
Queen of Pain
* Husker is the kind of hero that likes to remain at low health, which is perfect for Queen of Pain to burst with Sonic Wave.
* She should be able to Blink away after he jumps on her with 
Life Break.
Outworld Destroyer
* Heroes with pure damage can kill Huskar when he inevitably gets low on health: Outworld Destroyer, 
Silencer.
Additional:
* Outworld Destroyer can dodge Life Break with Astral Imprisonment, leaving him unharmed while Huskar loses HP.
* Sanity's Eclipse can deal massive damage to Huskar before he builds up his 
Berserker's Blood stacks due to Huskar's low mana pool.
Queen of Pain
* Timbersaw has a difficult time against magical and pure damage: 
Lina, 
Leshrac, 
Enchantress, Queen of Pain
Outworld Destroyer
* Arcane Orb's pure damage ignores Timbersaw's 
Reactive Armor.
* Astral Imprisonment, if timed correctly, can interrupt 
Timber Chain, preventing him from escaping.
Additional:
* Arcane Orb deals constant pure damage, which bypasses Timbersaw's Reactive Armor.
* Sanity's Eclipse can hit targets inside Astral Imprisonment, which helps Outworld Destroyer finish off Timbersaw before he escapes with Timber Chain. It can also drain his mana, limiting his ability to escape should he survive.
Queen of Pain
* Blinking heroes like Anti-Mage or Queen of Pain can often chase down an injured Brewmaster after his ultimate expires.
Outworld Destroyer
* Outworld Destroyer's pure damage will mop up Primal Split's units very quickly.
Queen of Pain
* Queen of Pain can be a good hero for dealing with Ember Spirit with 
Orchid Malevolence, her pure damage nuke in Sonic Wave and a slow in Shadow Strike. However, Queen of Pain can be punished by Ember Spirit, as his Searing Chains prevents her from getting Blink off.
Outworld Destroyer
* The pure damage provided by Arcane Orb is a great addition for killing Ember Spirit.
* Astral Imprisonment fully negates all magic damage of Flame Guard and Searing Chains and will temporarily save himself from Sleight of Fist's physical damage, and Ember Spirit is not a hero that can counter these skills.
Outworld Destroyer
* Any heroes with high intelligence, such as Invoker and Pugna.
Queen of Pain
* Queen of Pain usually outlanes Invoker, giving her team a significant early game advantage while Invoker is still farming.
* Blink allows Queen of Pain to escape from Invoker's combo if he doesn't have disables.
Outworld Destroyer
* Astral Imprisonment allows Outworld Destroyer to save himself or ally from Invoker's combo, or remove Invoker from a fight temporarily.
* Arcane Orb's pure damage will deal a lot of damage against Invoker's mediocre strength gain.
* E.M.P. is useless against Outworld Destroyer by activating 
Equilibrium.
* However, be aware that Sanity's Eclipse will most likely not deal any damage at all, due to Invoker's high intelligence gain compared to Outworld Destroyer's.
Queen of Pain
* Heroes that rely on their high mobility such as Queen of Pain, Slark and Weaver can be constantly engaged against due to your excellent ability to chase over any terrain. Make sure you carry true sight items (such as 
Dust of Appearance or 
Gem of True Sight) for invisible heroes that could potentially escape your clutches.
Queen of Pain
* Queen of Pain outlanes Storm Spirit due to the fact that it has long-range abilities: Shadow Strike and 
Scream Of Pain. Storm Spirit's damage from the 
Overload ability is not enough to interrupt her on the line, and the 
Static Remnant will never reach Queen Of Pain, as she will scatter her abilities from afar, which is why she will drive Storm Spirit off the line and get a lot of gold and level, after such a stage of the liner, Queen of Pain will very quickly buy Black King Bar and will not let Storm Spirit catch and kill her at the expense of 
Electric Vortex
Additional:
* Queen of Pain outlanes Storm Spirit due to the fact that it has long-range abilities: Shadow Strike and Scream Of Pain. Storm Spirit's damage from the Overload ability is not enough to interrupt her on the line, and the Static Remnant will never reach Queen Of Pain, as she will scatter her abilities from afar, which is why she will drive Storm Spirit off the line and get a lot of gold and level, after such a stage of the liner, Queen of Pain will very quickly buy Black King Bar and will not let Storm Spirit catch and kill her at the expense of Electric Vortex
Outworld Destroyer
* Outworld Destroyer has a huge damage from Arcane Orb, which is why in a 1 on 1 skirmish Storm Spirit simply cannot defeat him in damage. Since Outworld Destroyer will stop gank Storm Spirit with his Astral Imprisonment, and then kill him if he decides to fight
Additional:
* Outworld Destroyer has a huge damage from Arcane Orb, which is why in a 1 on 1 skirmish Storm Spirit simply cannot defeat him in damage. Since Outworld Destroyer will stop gank Storm Spirit with his Astral Imprisonment, and then kill him if he decides to fight
Queen of Pain
* Heroes with blink or movement abilities, which are disabled by Pounce's leash: Anti-Mage, Earth Spirit, Faceless Void, 
Magnus, 
Mirana, 
Monkey King, 
Morphling, Pangolier, Phantom Assassin, 
Phoenix, Puck, Queen of Pain, Riki, 
Sand King, Spirit Breaker, 
Timbersaw, 
Tusk.
Queen of Pain
* Both Scream of Pain and Sonic Wave should hit Slark during his 
Shadow Dance.
Outworld Destroyer
* Outworld Destroyer can disrupt Slark's attacks with Astral Imprisonment either by banishing Slark or his target.
* Slark's low heathpool means he will die quickly to Arcane Orb if he is directly attacked by Outworld Destroyer
* Slark has low intelligence gain, making him easy to finish with Sanity's Eclipse if he tries to run with Shadow Dance
Additional:
* Arcane Orb deals pure damage, which ignores the armor granted from permanent agility stacks.
* Astral Imprisonment can disrupt any Pounce attempt by banishing the leashed ally.
* Slark's low mana pool makes him more susceptible to Sanity's Eclipse.
Queen of Pain
* Heroes that have superior mobility that can easily catch up with Mirana even after she used Leap to escape: Anti-Mage, Queen of Pain, Storm Spirit, Riki.
Outworld Destroyer
* Heroes that can protect or dispel stunned allies such as 
Legion Commander, Outworld Destroyer, Shadow Demon and Oracle can reduce the effectiveness of Sacred Arrow.
Queen of Pain
* Heroes with strong area-of-effect damaging and/or disabling abilities will be able to intercept Underlord and his team when they exit from Fiend's Gate: 
Luna's Aghanim's Scepter upgraded Eclipse, 
Dawnbreaker's 
Solar Guardian, 
Axe's 
Berserker's Call, 
Mars's 
Arena of Blood, Jakiro's 
Macropyre, 
Dual Breath and 
Ice Path, Naga Siren's 
Song of the Siren, 
Razor's 
Eye of the Storm and 
Plasma Field, Lina's Light Strike Array, 
Broodmother's 
Spinner's Snare from Aghanim's Scepter, 
Elder Titan's 
Earth Splitter and 
Echo Stomp, 
Alchemist's 
Unstable Concoction and 
Acid Spray, Queen of Pain's Sonic Wave, 
Dark Seer's 
Wall of Replica and 
Vacuum, 
Venomancer's 
Noxious Plague and 
Poison Nova from Aghanim's Scepter, Oracle's 
Fortune's End and 
Rain of Destiny from 
Aghanim's Shard, 
Bloodseeker's Blood Rite, Enigma's 
Black Hole and 
Midnight Pulse, 
Shadow Fiend's 
Requiem of Souls, 
Batrider's Aghanim's Scepter upgraded 
Flaming Lasso, 
Firefly, 
Flamebreak and 
Sticky Napalm, 
Ancient Apparition's 
Ice Blast, Sand King's 
Epicenter, 
Sand Storm and 
Burrowstrike, Gyrocopter's 
Call Down, Ember Spirit's 
Sleight of Fist, Death Prophet's 
Exorcism and Silence, Monkey King's 
Wukong's Command, 
Crystal Maiden's 
Freezing Field, 
Muerta's 
The Calling, 
Medusa's 
Stone Gaze, 
Zeus's 
Nimbus from Aghanim's Scepter. 
Dark Willow's 
Bramble Maze, Pangolier's 
Swashbuckle, 
Grimstroke's 
Soulbind, 
Ink Swell and 
Stroke of Fate, 
Earthshaker's 
Echo Slam and 
Fissure, Puck's 
Dream Coil and 
Waning Rift, Winter Wyvern's 
Winter's Curse, Magnus's 
Reverse Polarity.
Outworld Destroyer
* Tanky melee heroes that can easily be kited, which allows Outworld Destroyer to deal heavy damage with Arcane Orb from a distance: 
Sven, 
Underlord, 
Bristleback.
Additional:
* Arcane Orb's pure damage can do great damage to Underlord.
* Sanity's Eclipse can tear down Underlord's health by a large amount, since his mana pool is very low compare to Outworld Destroyer's high mana pool.
Outworld Destroyer
* Arcane Orb deals pure damage, effectively bypassing Morphling's high armor from Attribute Shift (Agility Gain).
* Sanity's Eclipse is more effective against a low health and mana pool Morphling, enabling Outworld Destroyer to burst Morphling down before he can shift to Strength.
Additional:
* Arcane Orb deals high damage regardless of Morphling's high armor from 
Attribute Shift (Agility Gain).
* Because of Morphling's very low intelligence gain and base intelligence, Sanity's Eclipse will almost always be effective against Morphling.
Outworld Destroyer
* Arcane Orb and Sanity's Eclipse can often kill Chen or his allies before he can save them with 
Hand of God.
* Arcane Orb, Astral Imprisonment and Sanity's Eclipse can clear waves of Chen's converted creeps.
Outworld Destroyer
* Astral Imprisonment allows Outworld Destroyer to waste over half of 
Pierce the Veil, or protect an ally from Dead Shot's fear while also reducing Muerta's maximum mana.
* Sanity's Eclipse will deal massive damage to Muerta if her maximum mana gets too low. And even if she survives it, Sanity's Eclipse's Mana Allergy debuff will discourage her from using abilities as that will result in healing Outworld Destroyer.
Queen of Pain
* Blink allows Queen of Pain to avoid ganks and keep her distance, preventing Monkey King from building up Jingu Mastery.
* Scream of Pain and Sonic Wave will hit Monkey King when he is disguised, or on a tree.
* The large AoE and low cooldown also helps Queen of Pain hit the real Monkey King inside of Wukong's Command.
Outworld Destroyer
* Arcane Orb allows Outworld Destroyer's attacks to deal pure damage that can bypass Naga Siren's armor, and which can clear her illusions in no time.
* Astral Imprisonment can be used to harass Naga Siren by reducing her maximum mana and to prevent Naga Siren from escaping with Song of the Siren. Outworld Destroyer can also use Astral Imprisonment to protect himself from Naga Siren.
* Sanity's Eclipse will most likely instantly kill Naga Siren along with her illusions. Even if Naga Siren survives Sanity's Eclipse, it's mana allergy debuff will discourage Naga Siren from using her abilities as the mana allergy will heal Outworld Destroyer if she uses them for it's duration.
Outworld Destroyer
* Outworld Destroyer's high burst damage is not negated by Bristleback's passive. So, even if Bristleback turns his back on Outworld, he can decimate Bristleback quickly.
* If Bristleback attempts to flee, or tries to close the gap, Outworld can banish him with Astral Imprisonment, both reducing Bristlebacks much needed mana and allowing Outworld to move in front of him, forcing him to take the full damage from his spells. This will also allow Outworld to land a devasting Sanity's Eclipse, without it being reduced by Bristleback's passive.
Outworld Destroyer
* Arcane Orb's pure damage ignores Mars' Bulwark.
* Astral Imprisonment can be used to stop Mars from being disruptive or save allies from his abilities.
* Sanity's Eclipse deals high damage to Mars, due to his low intelligence pool.
Queen of Pain
* Blink makes it hard for Gyrocopter to pin down Queen of Pain.
* Sonic Wave is very effective at ganking Gyrocopter in the early game.
Outworld Destroyer
* Arcane Orb's constant pure damage output is devastating to Dragon Knight.
* Dragon Knight's relatively low mana pool leads to heavy damage from Sanity's Eclipse, which also bypasses his armor.
Outworld Destroyer
* Astral Imprisonment is a versatile nuisance:
* If it is cast on a low-enough-health unit at least 1 second into Shallow Grave's duration, the Shallow Grave will end during the imprisonment, and the target will take lethal damage when released.
* It can be used remove Dazzle from the fight at a time he could have saved someone.
* It lets himself or an ally dodge all of Poison Touch's effects, for long enough to recover their Blink Dagger.
Queen of Pain
* Heroes who recklessly jump on Pudge with their gap-closing abilities will be easy targets for Pudge's Meat Hook and Dismember Combo: Phantom Assassin, Faceless Void, Queen of Pain etc.
Queen of Pain
* Heroes with a high degree of mobility and invisibility are hard to catch with Meat Hook: Ember Spirit, Riki, 
Clinkz, Queen of Pain.
Outworld Destroyer
* Sanity's Eclipse deals more damage the less max mana the heroes hit by it have, making Pudge an ideal target.
* Outworld Destroyer can save allies or himself caught by Dismember or Meat Hook with Astral Imprisonment.
Outworld Destroyer
* Astral Imprisonment can be used to protect allies from Jakiro's various abilities, It can also be cast on Jakiro to break his combos (Macropyre into Ice path into Dual Breath), while at the same time, stealing his much needed mana.
* Aghanim's Shard upgraded Astral Imprisonment allows Outworld Destroyer and his allies to move while imprisoned, which allows them to leave the area of Jakiro's abilities.
* As Outworld Destroyer is prone to buying Meteor Hammer, he can combine it with Astral Imprisonment and Arcane Orb's high pure damage that can quickly decimate Jakiro, And unlike most heroes, Outworld doesn't particularly care who he targets.
* Outworld is also a common Black King's Bar carrier, and Jakiro's only tool to counter it is the Aghanim's Scepter upgraded Macropyre
Outworld Destroyer
* Kraken Shell's dispel does not restore mana lost through Astral Imprisonment, and the stolen mana can really hurt Tidehunter's ability to initiate
* Arcane Orb high pure damage ignores Tidehunter's Armor, and is barely affected by his Kraken Shell's damage block
* It is also completely unaffected by Anchor Smash, due to it relying on Outworlds Mana pool
* Sanity's Eclipse is effective on Tidehunter's poor mana pool, While it is reduced by Kraken Shell, the damage reduction is negligible.
Queen of Pain
* Heroes that rely on escapes to stay alive can be caught and locked down for a long time: Queen of Pain, Phantom Assassin
Queen of Pain
* Heroes that usually build Linken's Sphere as either a core or situational item: Weaver, Medusa, Morphling, Queen of Pain, Storm Spirit, Luna, Naga Siren.
Outworld Destroyer
* Astral Imprisonment can be used to protect allies by imprisoning either them or Spirit Breaker.
* Arcane Orb will heavily drain Spirit Breaker's maximum mana, rendering him almost useless and unable to cast spells. And considering how Spirit Breaker's intelligence is very low, Sanity's Eclipse will deal a lot of damage to him.
* Even if Spirit Breaker survives Sanity's Eclipse, mana allergy applied by the Sanity's Eclipse will discourage Spirit Breaker from using his abilities as it will cause him to lose health and heal Outworld Destroyer.
Outworld Destroyer
* Heroes with built-in spell immunity can become immune to all of Outworld Destroyer's spells: Lifestealer's Rage and Juggernaut's Blade Fury.
Queen of Pain
* Heroes with escaping and disjointing abilities can be good against Juggernaut:Anti-Mage Riki, Queen of Pain, Puck, Storm Spirit, Ember Spirit, Slark etc.
Outworld Destroyer
* Astral Imprisonment allows Outworld Destroyer to save himself or his teamates during 
Omnislash.
* Juggernaut's low mana from his low intelligence gain means that he'll take a lot of damage from Sanity's Eclipse.
Queen of Pain
* Queen of Pain, for the most part, almost exclusively deals magical damage, ignoring Windranger's evasion from 
Windrun.
* Queen of Pain is also a common wielder of Orchid Malevolence, preventing Windranger from using her abilities for a while.
* Blink, when used correctly, allows Queen of Pain to dodge 
Powershot and 
Shackleshot.
Outworld Destroyer
* Outworld Destroyer's pure and magical damage is particularly effective against Earthshaker.
* Astral Imprisonment catches Earthshaker while he blinks in, preventing him from executing his combo.
* Earthshaker has mana troubles, and Outworld Destroyer's abilities can press this by stealing intelligence comes from Arcane Orb, therefore depleting his mana pool and mana regeneration.
* Sanity's Eclipse deals high damage to Earthshaker, due to his low intelligence and mana pool.
Queen of Pain
* Blink allows Quen of Pain to easily escape ganking or initiating attempts with Hookshot and Power Cogs.
Outworld Destroyer
* Astral Imprisonment can save allies from a Black Hole combo. When upgraded with Aghanim's Scepter and Aghanim's Shard, it becomes exceedingly difficult for Enigma to land a good Black Hole against Outworld Destroyer and his team.
* Astral Imprisonment can also cancel Black Hole while Enigma does not have Black King Bar.
* Arcane Orb and Sanity's Eclipse can often make a short work out of Enigma and his Eidolons.
Queen of Pain
* Queen of Pain can easily escape Chain Frost thanks to Blink.
* His low survivability makes an easy kill for Shadow Strike, Scream of Pain & Sonic Wave.
Outworld Destroyer
* Sanity's Eclipse does massive damage to Wraith King who naturally has a low mana pool and typically doesn't build items to increase it.
* 
Wraithfire Blast's slow projectile speed makes it easy to avoid using Astral Imprisonment.
Outworld Destroyer
* Arcane Orb deals heavy damage to both Lone Druid and the Spirit Bear.
* Astral Imprisonment can prevent the Spirit Bear from attacking, which is Lone Druid's main damage output.
* Sanity's Eclipse deals heavy damage to Lone Druid.
Outworld Destroyer
* Outworld Destroyer's pure damage from Arcane Orb can go through 
Cold Embrace.
* Outworld Destroyer can negate the healing from Cold Embrace using Astral Imprisonment, and steal mana while doing so.
* Outworld Destroyer's damage during Winter's Curse is reduced due to Arcane Orb being unable to target allies.
Additional:
* Winter Wyvern must never put her allies in Cold Embrace against Outworld Destroyer as Arcane Orb will continue to deal damage to the defenseless hero.
* Arcane Orb does not hit his allies when he is taunted by Winter's Curse, making it weak against allies, but strong versus enemies.
* Astral Imprisonment can protect a target inflicted with Winter's Curse.
Outworld Destroyer
* Arcane Orb's pure damage penetrates Guardian Angel's defense.
* Astral Imprisonment's mana steal is devastating to Omniknight's already low mana pool.
Outworld Destroyer
* Astral Imprisonment wastes Borrowed Time's duration.
* Outworld Destroyer's Sanity's Eclipse can kill Abaddon before Borrowed Time triggers due to the lack of intelligence for Abaddon.
Outworld Destroyer
* Batrider prevents sharp and brazen attacks of the opponent. First he catches him in a Flaming Lasso, and then causes huge damage, in some cases even incompatible with life.
Additional:
* Batrider prevents sharp and brazen attacks of the opponent. First he catches him in a Flaming Lasso, and then causes huge damage, in some cases even incompatible with life.
Queen of Pain
* Queen of Pain can be an effective tool against Batrider in the game and on the line. She has long-range abilities such as Scream of Pain or Sonic Wave and a long-range type of attack, which is why she can keep Batrider at a distance all the time, and prevent him from attacking with Flaming Lasso or Firefly. Queen of Pain has an effective high-deceleration ability against Batrider - Shadow Strike, which is why he cannot quickly set fire to all enemies under Firefly and fly between all Queen of Pain allies. In addition, Queen of Pain has a wonderful escape in stock - Blink, which can save her at any moment in which batrider decides to attack
Additional:
* Queen of Pain can be an effective tool against Batrider in the game and on the line. She has long-range abilities such as Scream of Pain or Sonic Wave and a long-range type of attack, which is why she can keep Batrider at a distance all the time, and prevent him from attacking with Flaming Lasso or Firefly. Queen of Pain has an effective high-deceleration ability against Batrider - Shadow Strike, which is why he cannot quickly set fire to all enemies under Firefly and fly between all Queen of Pain allies. In addition, Queen of Pain has a wonderful escape in stock - Blink, which can save her at any moment in which batrider decides to attack
Outworld Destroyer
* Shadow Demon, Outworld Destroyer and Tusk can all save a Lasso'd teammate with their defensive spells.
Queen of Pain
* Heroes with mobility spells (such as Queen of Pain's Blink and Clockwerk with 
Hookshot) can easily avoid 
Lil' Shredder and 
Mortimer Kisses.
* Heroes with high movement speeds like Pugna and Meepo can run around, to, or away from Snapfire during Mortimer Kisses and dodge the projectiles easily due to their slow speed.
Outworld Destroyer
* Most Illusion based heroes (like Chaos Knight and 
Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.
Additional:
* Arcane Orb deals pure damage against the real Terrorblade, which allows it to bypass his high base armor.
* Arcane Orb and Sanity's Eclipse will make very short work of Terrorblade and his illusions.
* Aghanim's Shard upgraded Astral Imprisonment can be used to save an ally on which Terrorblade has used 
Sunder.
Queen of Pain
* Heroes that can jump on her: Slark, Queen of Pain, Anti-Mage
Additional:
* Queen of Pain often relies more on abilities than right-clicks, making 
Untouchable nearly useless against her.
* Enchantress also has a lower health pool than Queen of Pain, making her vulnerable to Queen of Pain's damage burst.
Queen of Pain
* Heroes with mobility spells can quickly escape from Stroke of Fate or break out of Soulbind: Anti-Mage, Queen of Pain, Morphling, Storm Spirit
Outworld Destroyer
* Most Illusion based heroes (like Chaos Knight and Terrorblade) can't use their illusion beneficially against Sanity's Eclipse's high AoE burst damage.
Queen of Pain
* Heroes with teleports to escape Solar Blind and Will-O-Wisp: Phantom Assassin, Puck, Queen of Pain, Storm Spirit
Queen of Pain
* Heroes with high burst damage: Lina, Lion, Luna, 
Nyx Assassin, Queen of Pain.
Outworld Destroyer
* Primal Beast is mostly played in the offlane role, so picking a carry who can escape from him is essential. Heroes such as 
Troll Warlord, 
Lone Druid and Outworld Destroyer, or generally any carry with a stun, slow or ability to fight back will stop him from having the good start he needs.
Outworld Destroyer
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.
Additional:
* Outworld Destroyer's pure damage from Arcane Orb is very effective at killing Troll Warlord quickly.
* Astral Imprisonment removes Troll Warlord from a fight for four seconds, minimizing his contribution to a teamfight, and potentially wasting over half of Battle Trance's duration.
* Troll Warlord gains a measly 1 intelligence point per level, meaning Sanity's Eclipse is especially effective, often instantly killing him.
Queen of Pain
* Heroes with mobility/escape mechanisms to dodge Ancient Apparition abilites, or to easily jump on him: Riki, Queen of Pain, Phantom Assassin, 
Windranger, 
Bounty Hunter, Spirit Breaker, Night Stalker, Storm Spirit, Juggernaut, etc.
Outworld Destroyer
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.
Queen of Pain
* Dark Seer's only disable is Vacuum. Though he starts off with high armor and health, he'll eventually have a hard time dealing with high mobility heroes such as Weaver or Queen of Pain.
Outworld Destroyer
* Tanky melee heroes that can easily be kited, which allows Outworld Destroyer to deal heavy damage with Arcane Orb from a distance: Sven, Underlord, Bristleback.
Queen of Pain
* Heroes who have a high mobility (Queen of Pain, Storm Spirit, Slark, etc.).
Queen of Pain
* Heroes with damage over time abilities can quickly eat through Gravekeeper's Cloak charges like 
Huskar, Jakiro and Queen of Pain.
Outworld Destroyer
* Ursa struggles against heroes with strong (and especially undispellable) disables (
Disruptor, Puck, Shadow Demon, Outworld Destroyer and etc).
Queen of Pain
* Heroes that have escape abilities (such as Queen of Pain, Storm Spirit or Timbersaw) can be either nullified by Reaper's Scythe or a complimentary item for Necrophos (like 
Rod of Atos or 
Scythe of Vyse). If Necrophos is quick enough and enters range, they can quickly, if not instantly, die if they are not quick enough.
Outworld Destroyer
* Outworld Destroyer is not exceptionally dangerous to Necrohpos because of his Ghost Shroud, but his Astral Imprisonment can save his allies from Necrophos's Reaper's Scythe, though only if he uses it at the right time, If an Outworld Destroyer is nearby, Necrophos should not use Reaper's Scythe unless he has banished himself, or has banished two heroes within 15 seconds
Outworld Destroyer
* Heroes who take a long time to become strong are in for a rough mid game, such as Outworld Destroyer, Magnus, Medusa, and Anti-Mage.
Queen of Pain
* Queen of Pain can Blink to both escape and initiate onto Void Spirit.
* She is also a very common Orchid Malevolence carrier, which can prevent Void Spirit from contributing much in fights.
Queen of Pain
* Heroes with gap-closing abilities will be easy targets for Berserker's Call: Phantom Assassin, Faceless Void, Slark, Chaos Knight, Morphling, Queen of Pain
Additional:
* Berserker's Call prevents Queen of Pain from escaping with Blink and also pierces her Black King Bar.
* Due to her fast attack speed from 
Mjollnir, it will quickly trigger 
Counter Helix.
* 
Culling Blade finishes off Queen of Pain's low health pool before she gets a chance to escape, preventing her from playing the hit-and-run style often associated with Queen of Pain.
Outworld Destroyer
* Outworld Destroyer's pure and magical damage is particularly effective against Axe.
* Astral Imprisonment is an excellent way to defend against an initiating Axe.
* Sanity's Eclipse deals high damage to Axe due to his low mana pool.
Additional:
* Berserker's Call bonus armor doesn't block Arcane Orb's pure damage.
* Astral Imprisonment can be used to prevent an ally or Outworld Destroyer himself from an Axe initiation.
* Axe's low mana means he's susceptible to a powerful Sanity's Eclipse.
Outworld Destroyer
* Any heroes with silences can negate the majority of Outworld Destroyer's damage output: Death Prophet, Night Stalker, Drow Ranger, Doom .
Outworld Destroyer
* Any heroes with low mana pools will die quickly or even instantly to Sanity's Eclipse: Doom, Phantom Assassin, Troll Warlord.
Queen of Pain
* Any Hero with high mobility will be neutralized by dream coil: Queen of Pain, Storm Spirit, Ember Spirit, Lycan, Bloodseeker, Anti-Mage, Timbersaw.
Additional:
* Puck will make a game of dodging as many Shadow Strikes as he can with 
Phase Shift. If he's a good player, he will also dodge Sonic Wave. If he's a great player, he will also dodge Scream of Pain, and it's all thanks to this single spell.
* Puck also has a silence in Waning Rift to prevent Queen of Pain from blinking away.
* Puck can provide vision to hunt her down if she blinks into the trees with 
Illusory Orb.
* If Queen of Pain is under the effect of Dream Coil, she will be unable to blink out.
Queen of Pain
* Once you farm up an Orchid Malevolence or a Scythe of Vyse, you're suddenly a lot more fearsome to elusive heroes like Storm Spirit or even that pesky Puck.
Queen of Pain
* Because Queen of Pain's spells cost a decent amount of mana, Anti-Mage can easily use 
Mana Void if she spams her spells recklessly.
* Anti-Mage has similar mobility through 
Blink, which can allow him to catch up to or flee from her.
* 
Counterspell will reduce the damage done by Shadow Strike and Scream of Pain. Additionally, its active component also reflects Shadow Strike back at her if Anti-Mage times it right.
Outworld Destroyer
* Arcane Orb's pure damage, making Counterspell ineffective.
* Sanity's Eclipse will hit Anti-Mage while he is disabled from Astral Imprisonment, and forces him to take heavy damage due to his low intelligence.
* 
Essence Flux keeps Outworld Destroyer at high mana, thus greatly reducing the damage from Mana Void.
Additional:
* Counterspell doesn't work versus Arcane Orb because it does pure damage.
* Anti-Mage cannot burn all of Outworld Destroyer's mana without disables due to Essence Flux.
* Anti-Mage's 
Manta Style illusions are quickly destroyed by Arcane Orb.
* However, if the enemy has multiple means of removing mana, Mana Void becomes a threat to Outworld Destroyer, Anti-Mage has better mobility than Outworld Destroyer with Blink, and Counterspell blocks a large portion of the damage from Sanity's Eclipse.
Queen of Pain
* A good Skywrath Mage with quick fingers will punish Queen of Pain for blinking aggressively. 
Ancient Seal is a six second silence with no cast time, so he can interrupt either her Shadow Strike or Sonic Wave, and a good 
Mystic Flare on top of that will seal the deal for her.
* Ancient Seal also has pretty good range so he could get it off before she blinks away.
Outworld Destroyer
* Outworld Destroyer can steal more mana with Astral Imprisonment from 
Skywrath Mage with 
Shield of the Scion (granted by Aghanim's Shard). Shield of the Scion grants Skywrath Mage bonus intelligence every time he deals magic damage to an enemy hero with his abilities. The higher his intelligence, the larger his mana pool. Since Astral Imprisonment steals based on the target's max mana, Outworld Destroyer can steal much more mana from Skywrath Mage.
Queen of Pain
* Ghostship helps your team soak up damage from Sonic Wave and Scream of Pain.
* Queen of Pain can't escape easily from X Marks the Spot - Torrent combo.
* Outlanes Queen of Pain on the midline, due to the fact that Queen of Pain has a small reserve of health at the beginning of the game, and she suffers very much from 
Tidebringer, which is why she is forced to either spend money on 
Tango, or skip creeps and run for bounty runes, and Kunkka at this time will gain an advantage in level and gold.
Additional:
* Outlanes Queen of Pain on the midline, due to the fact that Queen of Pain has a small reserve of health at the beginning of the game, and she suffers very much from Tidebringer, which is why she is forced to either spend money on Tango, or skip creeps and run for bounty runes, and Kunkka at this time will gain an advantage in level and gold.
* Kunkka will catch her in 
X Marks the Spot and allow his team to kill her for stun from 
Torrent, because Queen of Pain has no way to avoid the cross X Marks the Spot before buying Black King Bar.
Outworld Destroyer
* Astral Imprisonment can allow Outworld Destroyer to save himself or allies from Kunkka's full kit.
* Sanity's Eclipse deal a large amount of damage, as Kunkka's mana pool is much smaller than Outworld Destroyer's.
* Arcane Orb deals pure damage, shredding through Kunkka and his team even with Ghostship's buff.
Outworld Destroyer
* Shadow Demon's 
Disruption will allow his allies to maneuver around you. It can also be used to protect an ally from your abilities, or Astral Imprisonment - Meteor Hammer combo.
* 
Disseminate turns your high damage Arcane Orb and Sanitiy's Eclipse against you and your teammates.
* Scepter upgraded 
Demonic Purge will break your Essence Flux passive for 7 seconds, preventing you from regaining mana, and severely hindering your damage output.
Queen of Pain
* All of Queen of Pain's abilities are active, making Demonic Purge break from Aghanim's Scepter useless.
* However, Demonic Purge can help his allies kill a squishy Queen of Pain.
* Blink allows Queen of Pain to escape from Shadow Demon's abilities if he doesn't have disables.
* An attempt to save an ally using Disruption can easily become a perfect setup for a Sonic Wave for the enemy.
Queen of Pain
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, 
Lich, Magnus, Mars, Medusa, Outworld Destroyer, Phoenix, Puck, Queen of Pain, Shadow Fiend, 
Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.
Outworld Destroyer
* Heroes that depend on disrupting fights with ability combos or big ultimate abilities are vulnerable to the long stun of Fiend's Grip: Disruptor, Death Prophet, Enigma, Faceless Void, Invoker, Lich, Magnus, Mars, Medusa, Outworld Destroyer, Phoenix, Puck, Queen of Pain, Shadow Fiend, Treant Protector, Underlord, Winter Wyvern, Witch Doctor, Zeus.
Queen of Pain
* Heroes who commonly buy Linken's Sphere: Luna, Weaver, Morphling, Queen of Pain, Ember Spirit.
Outworld Destroyer
* Heroes with hiding abilities can protect disabled allies: Outworld Destroyer, Shadow Demon, Tusk, Phoenix with Aghanim's Scepter.
Queen of Pain
* 
Duels prevents Queen of Pain from using Blink, which may force her to purchase a Linken's Sphere
* Because Queen of Pain is also not a right-click hero, Legion won't have much difficulties in duels.
* 
Press the Attack dispels Shadow Strike's debuff.
Outworld Destroyer
* Astral Imprisonment prevents Legion Commander from killing her opponents in Duels.
Additional:
* Outworld Destroyer can save an ally hero caught by Duel with Astral Imprisonment, and he can inflict heavy damage on Legion Commander with Arcane Orb to aid his ally. However, if he gets caught, he is unlikely to survive the duel, due to his lack of durability.
Queen of Pain
* A good Nyx can reflect Queen of Pain's Sonic Wave with his
Spiked Carapace, or even initiate a gank on her in 
Vendetta while she farms a creep wave with Scream of Pain.
Dagon, provided he can get his full combo off.
* Her strength to intelligence ratio is bad enough that he should be able to kill her without even requiring a
Outworld Destroyer
* Outworld Destroyer's high intelligence gain and fragility makes him an easy target for a massive Mana Burn, as well as killing him outwards with Nyx Assassin's high burst damage.
Astral Imprisonment can be easily exploited by Nyx Assassin with his abilities. As long as Astral Imprisonment was not cast on Nyx Assassin, it will make an opportunity for an easy stun, either by Spiked Carapace (if Outworld Destroyer hid his allies or your allies) or Impale (if he hid himself). If Astral Imprisonment was cast on Nyx Assassin, using Spiked Carapace while banished will proc the stun after the disable, since Spike Carapace has a 0 second cast time and Astral Imprisonment deals damage right after the disable ends.
Sanity's Eclipse and/or well timed Spiked Carapace can deal a lot of damage to Outworld Destroyer and stun him, unless Outworld Destroyer used 
Black King Bar beforehand.
Mind Flare.
Spiked Carapace will return the full damage from Sanity's Eclipse back to Outworld Destroyer. Even a reflected Arcane Orb can deal significant damage and make him vulnerable to a follow-up from Nyx Assassin.
Spiked Carapace is also the perfect tool against Astral Imprisonment: if used on Nyx, he can reflect the damage back as he comes out of the prison by casting the ability while imprisoned.
*
* An ill-timed
Additional:
* Outworld Destroyer's high intelligence makes him a good target for
* If timed correctly,
*